- Cancer Evolution
- Computational Biology
- Genomics
- +۴ مورد دیگر
Andrea Sottoriva is the Head of the Computational Biology Research Centre at Human Technopole , Milan, Italy, and holds the title of Professor of Cancer Genomics and Evolution . His work bridges computational biology, evolutionary theory, and clinical oncology to predict cancer progression and design adaptive treatment strategies. University of Bologna – BSc in Computer Science (2006) University of Amsterdam – MSc in Computational Sciences (2008) University of Cambridge – PhD in Computational Biology (2012) Dr. Sottoriva's research focuses on cancer evolution , applying machine learning and population genetics to decode tumor heterogeneity through multi-omics data. His lab integrates patient-derived organoids and spatial genomics to understand how genetic and epigenetic factors drive cancer progression. The 15 most recent publications demonstrate a consistent emphasis on subclonal dynamics (7/15), computational methods (6/15), and evolutionary modeling (5/15). Key themes include adaptive mutability in colorectal cancer , immune editing in post-transplantation relapses, and deep learning applications for tumor heterogeneity. Scientific recognition includes: Cancer Research UK Future Leaders in Cancer Research Prize (2016) His lab currently trains PhD students and postdoctoral researchers in computational oncology, maintaining a living biobank of patient-derived models while pioneering AI-mechanistic hybrid models for clinical translation.






