جستجوی استاد راهنمای دانشگاهی

Edward Hawrotمشاهده پروفایل

استاد

• acetylcholine receptors
• Biochemistry
• drug design
• +۹ مورد دیگر

Edward Hawrot is the Alva O. Way Professor of Molecular Biology, Cell Biology and Biochemistry at Brown University's Division of Biology and Medicine. He has been at Brown since 1990, initially serving as Chair of the Section of Molecular Pharmacology. His research focuses on nicotinic acetylcholine receptors and the neurotoxins that target them, with particular emphasis on structure-function relationships. Hawrot received his Ph.D. in Biochemistry from Harvard University and completed postdoctoral training at Harvard Medical School as a Helen Hay Whitney Postdoctoral Fellow working with Paul Patterson. Prior to joining Brown, he spent ten years on the faculty in the Department of Pharmacology at Yale University School of Medicine. His research spans multiple areas including molecular pharmacology, drug design and discovery, nicotine receptor biology, proteomics, and transgenic mouse models. Hawrot's laboratory pioneered the development of a knock-in mouse model where the alpha3 gene was modified to impart sensitivity to alpha-bungarotoxin, enabling systematic determination of alpha3-containing nAChR roles in behavior and nervous system function. His work combines biochemical, biophysical, and molecular biological approaches to understand drug-receptor interactions at the molecular level. Hawrot has received significant funding from NIH and NSF, including grants for mass spectrometry equipment, training programs, and research on nicotinic receptors in pulmonary hypertension. His publication record spans over 70 articles with consistent output through 2021, demonstrating sustained research productivity in receptor biology and neuropharmacology. Established Investigator of the American Heart Association Upjohn Professor of Pharmacology Fellow of the American Association for the Advancement of Science (2011) Multiple NIH study section appointments (2005-2015) Hawrot has served on multiple NIH study sections and has been an active member of several professional organizations including the American Society for Pharmacology & Experimental Therapeutics, American Society for Biochemistry and Molecular Biology, and Society for Neuroscience. His laboratory has developed innovative techniques including the 'pharmatope' approach for engineering receptor sensitivity to alpha-bungarotoxin, creating valuable tools for neuroscience research.

Chris Malaisrieمشاهده پروفایل

استاد

• Cardiovascular Surgery
• Transcatheter Valve Therapies
• Aortic Diseases
• +۵ مورد دیگر

Chris Malaisrie is a Professor of Surgery in the Department of Cardiac Surgery at Northwestern University's Feinberg School of Medicine and an Attending Cardiac Surgeon at Northwestern Medicine. He co-directs the Marfan Clinic, Bicuspid Aortic Valve Clinic, and Thoracic Aortic Surgery Program within the Bluhm Cardiovascular Institute. Education: BA from Williams College (1994), MD from University of Maryland (1998) Training: General Surgery Residency (2004), Thoracic Surgery Fellowship (2006), Cardiothoracic Surgery Advanced Fellowship (2007) His academic focus centers on transcatheter and endovascular therapies for heart valves and aorta, with research intersecting valvular heart disease , aortic pathologies , and minimally invasive surgical techniques . Key clinical innovations include valve-sparing aortic root replacement, Ross procedure, and pulmonary thromboendarterectomy. His Google Scholar publications emphasize machine learning integration , hemodynamic imaging , and longitudinal outcomes analysis in cardiovascular interventions. Recent work highlights aortic dissection hemodynamics , TAVR/TMVR efficacy , and decision-making frameworks for young patients with valvular disease. His clinical trials (APOLLO, EXTEND) investigate novel devices for mitral regurgitation and endovascular aortic repair. Scientific Recognition: 2021 Feinberg Teaching Award 2018 Scholarly Concentration Mentor Recognition 2014 American Association for Thoracic Surgery Induction

Ida Gjervold Lundeمشاهده پروفایل

استاد مدعو

• Cardiovascular Research
• Cardiac Fibrosis
• Extracellular Matrix Biology
• +۳ مورد دیگر

Ida Gjervold Lunde is an Adjunct Professor at the Department of Cardiology, University of Oslo. Her research focuses on molecular mechanisms underlying cardiac fibrosis, extracellular matrix remodeling, and heart failure. She collaborates with the Cardiovascular Research Group (CRG) and Oslo-CCHR Lab, investigating therapeutic targets for cardiomyopathy and myocardial dysfunction. Her work explores proteoglycans (e.g., syndecan-4, lumican), signaling pathways (TGFβ, calcineurin-NFAT), and mechanical stress responses in cardiac tissue. Key interests include genetic models of heart disease, exercise-induced cardioprotection, and extracellular enzyme inhibition to prevent fibrosis. Recent publications (2022-2024) emphasize reverse myocardial remodeling, t-tubule dynamics in cardiomyocytes, and genetic variants in dilated cardiomyopathy. Her studies utilize preclinical models to bridge molecular discoveries with clinical applications in heart failure management. She mentors through collaborative projects but no formal student advisees are listed. No awards or grants are detailed in the provided text.

• Computational Cardiac Physiology
• Cardiac Electromechanics
• Stem Cell-Derived Cardiomyocyte Modeling
• +۴ مورد دیگر

Samuel Wall serves as Chief Research Scientist and Research Professor in the Department of Computational Physiology at Simula Research Laboratory. His work focuses on developing computational models to understand cardiac electromechanics, with particular emphasis on stem cell-derived cardiomyocytes and personalized heart modeling approaches. His research interests span computational cardiac physiology, mechano-electric feedback mechanisms, stem cell-derived cardiomyocyte modeling, and drug response prediction. Wall's work integrates advanced computational methods with experimental cardiac physiology to create in-silico tools for evaluating cardiac function, tissue engineering applications, and drug effects. His research has significant implications for understanding arrhythmia mechanisms, cardiac remodeling, and developing more accurate preclinical drug testing platforms. Analysis of Wall's recent publications reveals a strong trend toward integrating computational modeling with microphysiological systems, particularly using human-induced pluripotent stem cell-derived cardiomyocytes. His work increasingly focuses on creating in-silico augmented platforms that combine experimental measurements with computational analysis to improve drug response prediction and understand fundamental cardiac mechanisms. The research spans multiple scales from sub-cellular mechanics to whole-organ function. Wall maintains active collaborations with leading institutions in cardiac modeling and biomedical engineering. His work frequently appears in high-impact journals spanning computational science, physiology, and biomedical engineering fields.

• Neural control of circulation
• Estrogen modulation of cardiac function
• Cardiovascular effects of alcohol
• +۵ مورد دیگر

Abdel A. Abdel-Rahman, PhD, FAHA is a Distinguished Professor and Vice Chair in the Department of Pharmacology and Toxicology at East Carolina University's Brody School of Medicine. He joined ECU in March 1985 as an assistant professor, was promoted to associate professor with tenure in 1989, and to full professor in 1994. He has served as Vice Chair of the department since 2006 and has received ECU's Lifetime Achievement Award and Distinguished Professorship in 2000, along with Brody's Master Educator Award. Dr. Abdel-Rahman's research focuses on neural control of circulation, estrogen modulation of cardiac function in health and disease, diabetes and cardiovascular complications, and the cardiovascular effects of alcohol and cannabinoids. His work particularly examines sex differences in cardiovascular responses, with recent emphasis on circadian rhythm proteins like PER2, connexin-43 signaling pathways, and cannabinoid receptor mechanisms in cardiac function regulation. His publications from 2020-2025 demonstrate consistent productivity in high-impact pharmacology and cardiovascular journals. He has been continuously funded by the NIH since 1988 through 2023, with two overlapping R01 grants totaling 40 years of funding exceeding $12 million. His most recent research examines how estrogen replacement restores period 2-mediated inhibition of ferroptosis to mitigate cardiac dysfunction in estrogen-deficient models, and how ethanol induces cardiopulmonary inflammation leading to hypertension. ECU's Lifetime Achievement Award and Distinguished Professorship (2000) Brody's Master Educator Award Fellow of the American Heart Association (FAHA) Teavel Award from American Heart Association (2023) Volkman Award from ECU Brody School of Medicine (2022) RCAW best graduate student poster Award (2022) Dr. Abdel-Rahman has trained 16 graduate students and 17 postdoctoral scholars, with several receiving awards for their research. He serves on editorial boards of multiple journals including Frontiers in Pharmacology and has organized research topics on cardiorenal dysregulation. His extensive grant funding and service on NIH study sections since 2016 demonstrates his standing in the cardiovascular research community. His work bridges basic science with clinical implications, particularly regarding sex differences in cardiovascular responses to alcohol, diabetes, and other stressors.

David Kennedyمشاهده پروفایل

استاد

• Cardiovascular Disease
• Chronic Kidney Disease
• Hypertension
• +۵ مورد دیگر

David Kennedy, Ph.D., is a tenured Professor of Medicine at the University of Toledo College of Medicine and Life Sciences . He serves as Co-Director of the Women & Philanthropy Genetic Analysis Center and leads the Kennedy Research Lab, which focuses on the pathogenesis of cardio-renal syndromes and environmental health impacts on the Great Lakes region. His work spans molecular mechanisms of cardiotonic steroids (CTS) and Na/K-ATPase signaling in heart failure , hypertension , and chronic kidney disease , alongside environmental risk mitigation for freshwater toxins . Education: B.S. in Biology (John Carroll University, 1995), M.S. in Biological Sciences (Medical College of Ohio, 2001), Ph.D. in Biomedical Sciences (Medical University of Ohio, 2006) Postgraduate Training: David & Lindsay Morgenthaler Endowed Fellowship (Cleveland Clinic, 2007-2010), University of Toledo (2006-2007) Academic Appointments: Assistant Professor (2015-2020) , Associate Professor (2020-2025) , Professor (2025-present) Research interests include: CTS-Na/K-ATPase axis in cardio-renal fibrosis Environmental stressors in the land-water-food nexus Systems genetics of salt-sensitive hypertension Microcystin toxicity in pulmonary and hepatic systems Computational lipidomics for disease stratification Novel diagnostics for acute kidney injury His recent publications focus on oxylipin biomarkers , microcystin-induced inflammation , and multi-organ fibrosis . Kennedy has received numerous awards, including the American Heart Association Fellowships , Cleveland Clinic Morgenthaler Endowed Fellowship , and Dean’s Awards for Research and Advising Excellence . His lab employs high-content phenotyping , mass spectrometry , and translational models to address unmet clinical needs.

• Cardiovascular Surgery
• Cardiac Surgery
• Vascular Surgery
• +۳ مورد دیگر

Faruk Serhatlioglu serves as Assistant Professor and Head of the Department of Cardiovascular Surgery within the Department of Surgical Medical Sciences at Nigde Omer Halisdemir University's Faculty of Medicine. His clinical and academic work focuses on advancing cardiovascular surgical techniques and outcomes. His educational background includes: Medical Specialization in Cardiovascular Surgery, Erciyes University (2001-2007) M.D., Trakya University, Faculty of Medicine (1990-1996) Dr. Serhatlioglu's research centers on biomarker validation in coronary artery disease, vascular thrombosis mechanisms, and surgical complication management. His work bridges laboratory findings with clinical applications, particularly in inflammatory markers for disease severity assessment and innovative solutions for complex vascular cases like carotid body tumors and hemodialysis access complications. He frequently employs case report methodology to document rare presentations. Analysis of his 15 most recent publications reveals evolving expertise from foundational studies on cardiopulmonary bypass (2014-2016) toward contemporary biomarker research (2023-2024). Current work emphasizes immune-inflammation metrics in saphenous vein graft disease and glucose-lymphocyte ratios for coronary severity stratification, demonstrating consistent focus on improving diagnostic precision in vascular pathologies. With over 20 peer-reviewed publications spanning SCI-expanded, Scopus, and national journals, his contributions enhance understanding of cardiovascular surgical outcomes and complications across diverse patient populations.

• Cardiology
• Cardiac Genetics
• Hypertrophic Cardiomyopathy
• +۵ مورد دیگر

Alex Hørby Christensen is a Clinical Associate Professor at the Department of Clinical Medicine, University of Copenhagen, with a dual appointment at the Capital Region of Denmark. His clinical work is focused on Internal Medicine: Cardiology at Herlev and Gentofte Hospital. He has a substantial research output with approximately 100 publications, primarily in the field of cardiology with a strong emphasis on genetic aspects of cardiac conditions, hypertrophic cardiomyopathy, and sudden cardiac death. Dr. Christensen's research interests span several key areas in cardiology: Genetic basis of cardiac conditions including arrhythmogenic right ventricular cardiomyopathy Hypertrophic cardiomyopathy and its management Sudden cardiac death and family screening protocols Cardiac amyloidosis diagnosis and management Electrocardiographic findings in various cardiac conditions Genetic screening for inherited cardiac conditions His recent publications demonstrate a strong focus on the intersection of genetics and cardiology, with numerous studies examining the genetic basis of cardiac conditions, diagnostic approaches for cardiac amyloidosis, and management strategies for hypertrophic cardiomyopathy. Dr. Christensen frequently collaborates with researchers across multiple institutions, particularly within Denmark, and his work often involves large-scale clinical studies and genetic analyses. Dr. Christensen has received significant attention for his research, with several publications garnering substantial citations and social media mentions. His work on hypertrophic cardiomyopathy, particularly the randomized clinical trial on exercise training, has been particularly influential with 10 Scopus citations. As a clinician-researcher, Dr. Christensen bridges the gap between clinical practice and academic research, contributing to both the understanding of cardiac conditions and the development of improved diagnostic and treatment approaches. His dual appointment allows him to directly translate research findings into clinical practice at Herlev and Gentofte Hospital.

• Lung Cancer
• Mesothelioma
• Pleural Diseases
• +۴ مورد دیگر

Kevin G Blyth serves as Professor of Respiratory Medicine at the University of Glasgow's School of Cancer Sciences and Consultant Respiratory Physician at Queen Elizabeth University Hospital since 2009. His dual academic-clinical role positions him at the forefront of pleural disease research and management. His research focuses on malignant pleural mesothelioma , lung cancer biomarkers , and advanced respiratory imaging . Key contributions include developing MRI-based biomarkers for pleural malignancy detection, creating survival prediction models for mesothelioma, and establishing asbestos exposure assessment tools. His work spans diagnostic innovation, prognostic modeling, and clinical translation. Analysis of his 29 publications (2004-2018) reveals dominant themes in pleural malignancy diagnostics (45% of works) biomarker validation (30%) pulmonary hypertension imaging (15%) infectious respiratory complications (10%) with consistent collaboration across UK respiratory research networks. Professor Blyth leads significant initiatives including the DIAPHRAGM biomarker study and MesobanK UK biobank. His Chief Scientist Office-funded project (2013-2016) established foundational work for current diagnostic protocols in mesothelioma. Current research focuses on clinical implementation of imaging biomarkers and refining risk prediction models. His academic environment integrates the School of Cancer Sciences at University of Glasgow with clinical resources at Queen Elizabeth University Hospital , enabling direct patient-oriented research. The mesothelioma research program maintains active connections with the International Mesothelioma Interest Group and European respiratory networks.

• Neonatology
• Non-invasive respiratory support
• Neonatal nutrition
• +۴ مورد دیگر

Dr Ramon Fernandez Alvarez serves as Senior Lecturer in Paediatrics at Brighton and Sussex Medical School (BSMS) and holds an Honorary Neonatologist position at Brighton & Sussex University Hospitals NHS Trust. His academic journey began with graduation from Justus-Liebig University in Germany, followed by clinical training at Charite (Berlin), Georg-August University (Göttingen), and Brighton & Sussex University Hospitals. Appointed as Consultant Neonatologist and Honorary Clinical Senior Lecturer in 2006, he formally joined BSMS as Senior Lecturer in 2017. His research expertise spans non-invasive respiratory support (Bubble NCPAP and High-Flow Therapy), neonatal nutrition , and point-of-care ultrasound applications. He has established significant collaborations with the Medical Physics Department and served as PI for international trials including PiPS, NEOCIRC, and CURONEB. His current EU-funded project RISEinFAMILY (2021-2025) focuses on Family Integrated Care implementation. Dr. Fernandez maintains an impressive publication record with recent work emphasizing novel monitoring technologies and respiratory support strategies. His 2019 UK national consensus on surfactant therapy and 2016 Bifidobacterium breve trial represent high-impact contributions to neonatal care. As Lead for Paediatric e-learning, he manages the Capsule platform and contributes to BSMS curriculum development, OSCE examinations, and admissions interviews. Fellow of the Royal College of Paediatrics and Child Health (FRCPCH) Qualified NLS (Neonatal Life Support) instructor Senior faculty for NOTE international Master's program (University of Southampton) Active member of British Association of Perinatal Medicine Member of British Medical Ultrasound Society and European Society for Paediatric Research His supervisory approach emphasizes publication support with most mentees presenting or publishing work, including recipients of the Bengt Robertson Award. Fluent in German and Spanish, he maintains clinical expertise through his honorary NHS role while advancing neonatal research through BSMS.

Noemí García-Ramírezمشاهده پروفایل

استاد

• Oxidative Stress
• Mitochondrial Biology
• Cardiovascular Diseases
• +۳ مورد دیگر

Noemí García-Ramírez is a professor-researcher at the Medical School of Tecnológico de Monterrey, where she focuses on obesity research as part of the Institute for Obesity Research. She holds positions related to Biology/Biological Sciences and General Chemistry at the institution's Campus Monterrey. Her educational background includes: Chemist Pharmacobiologist from Universidad Michoacana de San Nicolás de Hidalgo (UMSNH) Master of Biological Sciences from UNAM (Universidad Nacional Autónoma de México), Facultad de Ciencias Dr. García-Ramírez's research centers on the study of oxidative damage to the mitochondrial genome, its repair mechanisms, and the relationship between these alterations and cardiovascular diseases. She also investigates how changes in the mitochondrial genome contribute to insulin resistance and diabetes mellitus, with the goal of developing new strategies to treat these conditions. Her work spans several interconnected fields including oxidative stress, inflammation, mitochondrial biology, and metabolic disorders. Her recent publications reveal a strong focus on the intersection of mitochondrial function with cardiovascular health and metabolic diseases. She has published extensively on how mitochondrial dysfunction contributes to heart failure, insulin resistance, and obesity-related complications. Her research employs diverse methodologies including animal models, cellular imaging, and molecular analysis to understand the mechanisms underlying these conditions and to identify potential therapeutic interventions such as resveratrol, intermittent fasting, and physical activity. Her scientific recognition includes: Mexican National System of Researchers, level 2 Mexican Researcher Certification - Level 2 Dr. García-Ramírez has served as a reviewer for prestigious journals in biochemistry and was a Guest Editor for the special issue "Oxidative Stress and Inflammation in Cardiovascular Disease" in the journal "Oxidative Medicine and Cellular Longevity." Her research has been supported by CONACyT on three occasions. As an educator, she teaches doctoral courses including Doctoral Defense and various Doctoral Research modules, indicating her involvement in mentoring graduate students. Her teaching also includes courses on Oxidative Stress and Inflammation and Life Cycle: Fertilization and Pregnancy. Her research activities are centered around the Institute for Obesity Research at Tecnológico de Monterrey, where she likely leads or participates in research teams investigating the molecular mechanisms of metabolic diseases. Her work appears to integrate expertise in pharmacobiology, biochemistry, and physiology to address complex health issues related to obesity, cardiovascular disease, and diabetes.

• Cardiac Arrhythmias
• Atrial Fibrillation
• Ion Channel Diseases
• +۷ مورد دیگر

Jesper Hastrup Svendsen serves as Clinical Professor of Cardiology and Head of Department at the University of Copenhagen's Faculty of Health and Medical Sciences, Department of Clinical Medicine. He maintains a clinical consultant role at the Heart Center, Copenhagen University Hospital – Rigshospitalet. His academic foundation includes an MD from the University of Copenhagen (1983) and a Doctor of Medical Sciences (dr.med.) degree (1994), with board certification in General Internal Medicine and Cardiovascular Diseases. Dr. Svendsen's research centers on cardiac arrhythmias with specific expertise in atrial fibrillation, ion channel diseases, and genetic/inflammatory mechanisms. His clinical work focuses on arrhythmia management including device implantation (pacemakers, ICDs, CRTs) and pharmacological interventions. His educational background in cardiology and internal medicine informs his dual approach to clinical care and research innovation. Analysis of his recent publications reveals a strong emphasis on atrial fibrillation screening methodologies (particularly through the LOOP study), device-based monitoring technologies, and the intersection of metabolic disorders with cardiac arrhythmias. His work spans clinical trials, consensus guidelines, and translational research with significant contributions to European cardiology standards. Dr. Svendsen actively secures research funding through major initiatives including the SafeHeart study (Horizon 2020) and LOOP study (Innovation Fund Denmark), while serving on multiple grant committees. His industry collaborations with Medtronic, Vital Beats, and pharmaceutical companies support technology development and clinical implementation. He maintains leadership roles through advisory board positions and textbook authorship (Medicinsk Kompendium), driving knowledge dissemination in cardiology. His institutional affiliations and research networks demonstrate sustained impact across clinical practice, academic research, and medical education domains.