جست‌وجوی استاد و پژوهشگر

Giorgio Dieciمشاهده پروفایل

استاد

• Molecular Biology
• Biochemistry
• Epigenetics
• +۳ مورد دیگر

Giorgio Dieci is a Full Professor at the University of Parma , affiliated with the Department of Chemical, Life, and Environmental Sustainability Sciences. His academic career spans decades of teaching and research in molecular biology disciplines. Biochemistry & Molecular Biology instruction (First/Second cycle degrees) Neurochemistry and Translational Biomedical Sciences Expertise in RNA biology and gene regulation Research focuses on transcriptional mechanisms , epigenetic regulation, and chromatin organization across various biological contexts: Molecular characterization of RNA:DNA triplex structures Interaction of viral proteins with chromatin remodeling complexes Role of TFIIIC in histone acetylation dynamics Non-coding RNA epigenetic control Transcription factor-DNA binding kinetics Recent publications demonstrate interdisciplinary approaches combining atomic force microscopy , chromatin remodeling , and transcriptional dynamics . Contact available via giorgio.dieci@unipr.it at Parco Area delle Scienze 23/A, Parma, Italy.

Manja Marzمشاهده پروفایل

استاد

• Bioinformatics
• Non-coding RNAs
• Aging Research
• +۵ مورد دیگر

Manja Marz is a Full Professor for High Throughput Sequencing Analysis at the Faculty of Mathematics and Computer Science, Friedrich Schiller University Jena, and an Associated Group Leader at the Leibniz Institute for Age Research - Fritz Lipmann Institute (FLI). Her research group focuses on non-coding RNAs and their regulatory roles in aging processes through interdisciplinary approaches combining bioinformatics with wetlab techniques. Her research interests include: Non-coding RNA identification and characterization in aging RNA:DNA triplex and G-quadruplex formations in genomic regulation High-throughput sequencing analysis, particularly RNA-Seq data Virus-bioinformatics and computational analysis of viral genomes Development of bioinformatics tools for ncRNA research Dr. Marz holds leadership positions in several research initiatives: Founding member and board member of the Aging Research Center (ARC) Jena since 2013 Founding member of the Michael Stifel Centre Jena for Data-Driven and Simulation Science since 2015 Founding member, board member and managing director of the European Virus Bioinformatics Center since 2017 Scientific advisory board member of RNA Central and Rfam since 2018 Her current research projects investigate ncRNAs as biomarkers of aging in mice and humans, the role of microRNAs in the short-living fish Nothobranchius furzeri, RNA:DNA triplexes in aging and cancer, and non-coding RNA elements in X-linked dystonia-parkinsonism. Notably, Dr. Marz is also an accomplished Go player (4 dan) with leadership roles in Go federations across Germany and Europe, serving as president of the Go Federation Brandenburg-Saxony-Thuringia since 2004 and managing director of the Jena International Go School since 2018.

• Molecular Biology
• Structural Biology
• Genomics
• +۳ مورد دیگر

Claudio Rivetti serves as a Full Professor in the Department of Chemical, Life and Environmental Sustainability Sciences at the University of Parma, where he teaches Molecular Biology and Structural Biology courses for Bachelor's and Master's programs in Biology and Biomolecular Sciences. His consistent teaching record spans from the 2013/2014 academic year through the upcoming 2025/2026 term across multiple cohorts. His research focuses on Molecular Biology and Structural Biology with specialization in Genomics , Enzymology , and Protein Science . Key interests include enzyme function in phosphonate catabolism, RNA:DNA triplex structures, membrane-permeabilizing peptides, and evolutionary adaptations of metabolic enzymes like uricase. He employs advanced techniques such as atomic force microscopy and genomic analysis to investigate these complex biological systems. Recent publications (2023-2025) reveal a diverse research trajectory spanning fundamental biochemical mechanisms, evolutionary adaptations in reptilian physiology, and practical applications in university resource management. His work bridges theoretical molecular biology with tangible solutions for academic infrastructure. Professor Rivetti holds regular office hours on Tuesdays and Thursdays (3:00-5:00 PM) and serves as the reference instructor ( Docente di riferimento ) for the Master's Degree program in Biomolecular, Genomic and Cellular Sciences since 2013/2014, demonstrating sustained commitment to graduate education and program leadership.

Holger Bierhoffمشاهده پروفایل

دانشیار

• Epigenetics
• Aging Research
• Non-coding RNA
• +۶ مورد دیگر

Holger Bierhoff serves as an Associate Group Leader at Friedrich Schiller University Jena with an associated position at the Leibniz Institute on Aging (FLI), operating from the Center for Molecular Biomedicine (CMB). His research group maintains a guest status collaboration with FLI while being primarily based at the university. Professor Bierhoff's research focuses on epigenetics of aging, specifically investigating how non-coding RNAs form RNA:DNA triplex structures to regulate chromatin landscape. His lab has developed novel molecular tools to detect and characterize these triplex structures genome-wide, examining how they compete with protein binding or alternative nucleic acid structures at target sites. Current work explores connections between ribosome biogenesis, nucleolar function, and aging processes using human and mouse cell models. His publication record shows consistent high-impact output, with multiple significant papers in 2024 including research on RNA:DNA triplexes as epigenetic communication mechanisms, rRNA synthesis and longevity in C. elegans, and breast cancer mechanisms. His work appears in prestigious journals such as Nature Communications, Cell Reports, and Nucleic Acids Research. Professor Bierhoff leads two major funded projects: AgingComb (funded by European Regional Development Fund) investigating genomic alterations through high-throughput DNA analysis, and 'Nucleolus as a target' (funded by European Social Fund) developing nucleolar changes as biomarkers for healthy aging. Both projects involve interdisciplinary collaborations between university researchers and clinical partners. His lab maintains active supervision of doctoral, master's, and bachelor students, creating a collaborative research environment focused on cutting-edge epigenetic mechanisms in aging. The group is embedded within the Zentrum für Alternsforschung Jena (ZAJ) and the Leibniz Research Alliance Resilient Ageing, providing students with access to advanced facilities and interdisciplinary networks.