جست‌وجوی استاد و پژوهشگر

• Roles of RNA-binding proteins in regulation of gene expression in bacteria
• Molecular Microbiology
• Regulatory RNAs: identification, mechanisms of regulation, functions
• +۳ مورد دیگر

Pascale Romby is a leading French molecular biologist and CNRS Researcher based at the Institute of Molecular and Cellular Biology (IBMC) in Strasbourg. She serves as Director of CNRS Unit UPR 9002 since 2016 and Team Leader of the 'Bacterial regulatory RNAs and mRNAs' group since 2004. Specializes in RNA biology and bacterial gene regulation Current focus on RNA-protein interactions and stress response networks Member of international/national scientific societies Active editorial and supervisory roles Research Interests : Romby's work centers on regulatory RNAs in bacteria, particularly their roles in virulence, stress responses, and host-pathogen interactions. Her team investigates RNA degradation machineries, translation control mechanisms, and the impact of small RNAs on bacterial persistence and metabolic adaptation. Publications Trends : Her recent work focuses on RNA targetome mapping in Gram-positive pathogens, ribosome structure-function relationships, and multi-layered regulatory networks controlling bacterial virulence. These studies employ biochemical, structural, and systems biology approaches. Scientific Honors : Recipient of the prestigious Pasteur Medal (2018) Langevin Prize by French Academy of Sciences (2010) CNRS Silver Medal (2006) and Bronze Medal (2003) FEBS Fellowship (1984) and Choucroun Prize (1984) Supervision & Leadership : Has mentored 15 PhD students, 10 postdocs, and 23 visiting researchers. Organized two major Jacques Monod Conferences on RNA regulation and delivered over 45 invited seminars worldwide.

• Microbiology
• Microbial Biotechnology
• Yeast Biotechnology
• +۷ مورد دیگر

Martin Altvater is a researcher at the Institute of Microbiology and Microbial Biotechnology within the Department of Biotechnology and Life Sciences at the University of Natural Resources and Life Sciences, Vienna (BOKU). He holds a Dr. sc. from ETH Zurich and a Dipl.-Biol., and his work focuses on microbial biotechnology, particularly yeast-based systems for sustainable bioproduction. His research spans ribosome assembly, fermentation technologies, and metabolic engineering for lactic acid production. His research interests include Microbiology, Microbial Biotechnology, Yeast Biotechnology, Ribosome Assembly, Sustainable Bioproduction, Lactic Acid Fermentation, Synthetic Biology, Industrial Biotechnology, Bioart, and Metabolic Engineering . These areas reflect a strong interdisciplinary focus on using microbial systems for industrial and environmental applications, particularly in the context of bioeconomy and sustainability. The trends in his recent publications highlight a dual focus: one on fundamental molecular mechanisms in yeast ribosome biogenesis and nuclear export, and another on applied biotechnological innovations for sustainable lactic acid production. His work integrates systems biology, metabolic engineering, and process optimization, often using Saccharomyces cerevisiae as a model and industrial host. A notable recent direction includes bioart collaborations, emphasizing science communication and public engagement. Scientific Awards: No specific awards or fellowships are listed in the available data. Advising and Grants: There is no public record of supervised theses or doctoral students. No research projects are currently listed under his name as principal investigator. However, he actively contributes to the scientific community as a reviewer for journals including Biotechnology Journal , Essays in Biochemistry , Bioengineering , BMC Biotechnology , and FEMS Microbiology Letters . Labs and Research Teams: Martin Altvater is affiliated with the Institute of Microbiology and Microbial Biotechnology at BOKU, where he conducts research in microbial systems and bioprocesses. He collaborates closely with leading researchers such as Diethard Mattanovich and Michael Sauer, known for their work in industrial biotechnology and systems biology. His work is embedded in a larger research ecosystem focused on sustainable bioproduction and synthetic biology.

• Pharmaceutical Sciences
• Biochemistry
• Molecular Biology
• +۳ مورد دیگر

Silvia Weiss is a researcher affiliated with the Faculty of Life Sciences at an unspecified institution, specifically within the Department of Pharmaceutical Sciences. Her work focuses on advanced drug delivery systems and genetic therapies. Research Interests: Utilizing splice-switching oligonucleotides for hepatic gene correction and developing degradable polypeptide architectures to enhance cellular uptake and biodistribution of therapeutic agents. Key areas include RNA processing, polymer science, and pharmacokinetics. Publications (2023-2025): Recent work explores endosomal escape mechanisms for efficient gene therapy and in vivo behavior of bottlebrush polypeptides. These studies contribute to pharmaceutical sciences, molecular biology, and biotechnology, with applications in hepatic disorders and targeted drug delivery.

Alexandra Lusserمشاهده پروفایل

استاد

• Chromatin remodeling
• Chromatin assembly
• Epigenetics
• +۵ مورد دیگر

Professor Alexandra Lusser serves as Professor and Deputy Head in the Department of Molecular Biology at Innsbruck Medical University, where she leads the Chromatin and Epigenetics Laboratory. Her research focuses on understanding the molecular mechanisms of chromatin assembly, remodeling, and epigenetic regulation at both DNA and RNA levels. Professor Lusser completed her PhD at the University of Innsbruck in 1998, followed by postdoctoral training at the University of California, San Diego (2001-2004) in the laboratory of Professor JT Kadonaga. She joined Innsbruck Medical University as Assistant Professor in 2004, achieved her Habilitation for Molecular Biology in 2008, was promoted to Associate Professor, and became a full Professor in 2019. Her research program investigates how eukaryotic DNA is organized in chromatin and how this organization affects DNA metabolism processes including transcription, replication, repair, and recombination. A significant portion of her work examines ATP-dependent chromatin assembly and remodeling mechanisms, variant histone assembly, and epigenetic mechanisms at the mRNA level, particularly mRNA base modifications such as 5-methylcytosine and their roles in mRNA metabolism and translation. Her publications reveal a strong focus on developing and applying innovative biochemical and genomic techniques to study RNA modifications and chromatin dynamics. Professor Lusser's extensive publication record spanning from 1996 to the present demonstrates consistent contributions to the fields of chromatin biology and RNA epigenetics. Her recent work shows particular emphasis on developing novel sequencing methods for RNA modification analysis, exploring the functional consequences of RNA modifications, and investigating the relationship between chromatin remodeling factors and neurological functions. HOECHST Award (1998) APART 3-year postdoctoral fellowship from the Austrian Academy of Sciences (2001) START Prize from the Ministry of Science and Research (2005) Member of the Young Curia of the Austrian Academy of Sciences (2008-2016) Research Award from the State Capital Innsbruck (2009) As Deputy Head of the Department of Molecular Biology, Professor Lusser contributes to departmental leadership while maintaining an active research program. Her laboratory has developed several important methodologies including TUC-Seq for measuring mRNA transcription and degradation rates, bisulfite sequencing for detecting 5-methylcytosine in RNA, and other innovative approaches for studying RNA modifications. Her work bridges molecular biology, biochemistry, and genomics, with implications for understanding fundamental biological processes and potential applications in disease research.

Xin Luمشاهده پروفایل

استاد

• p53 biology
• Programmed cell death
• Gene transcription
• +۵ مورد دیگر

Professor Xin Lu is Director of Research and Full Member at the Ludwig Institute for Cancer Research, Oxford Branch, and Professor of Cancer Biology at the University of Oxford. She has held prominent academic positions since 2007 at Oxford, following professorial roles at University College London (2004-2007) and Imperial College London (2000-2004). As Director of the Oxford Centre for Early Cancer Detection and Cancer Theme co-Lead at the NIHR Oxford Biomedical Research Centre, Professor Lu leads significant research initiatives focused on tumor suppression and cellular plasticity. Professor Lu received her academic training in China and the UK: BSc in Biochemistry from Sichuan University, China (1982) MSc in Cell and Molecular Biology from Cancer Institute, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing (1985) PhD in Cell and Molecular Biology from Imperial Cancer Research Fund and University College London, London, UK (1991) Professor Lu's research program centers on understanding molecular mechanisms that control cellular plasticity and suppress tumor growth. With a long-standing interest in the tumor suppressor p53 and the ASPP family of proteins, her work has revealed how cells change characteristics in response to external signals - a process fundamental to cancer initiation, metastasis, and therapy resistance. Her laboratory investigates selective transcription mechanisms, regulators of cellular plasticity in gastrointestinal cancers (particularly esophageal and gastric), and the influence of infections like Helicobacter pylori and Epstein-Barr Virus on cell plasticity and cancer development. The discovery of ASPP proteins as key regulators of p53 function represents a major contribution to the field. Analysis of Professor Lu's recent publications shows a consistent focus on cellular plasticity mechanisms, p53 family regulation, and the role of ASPP proteins in cancer and developmental disorders. Her work spans molecular, cellular, and tissue-level investigations, increasingly incorporating advanced techniques like single-cell RNA sequencing and organoid models to study cancer initiation and progression. Professor Lu's significant contributions to science have been recognized with numerous prestigious awards: Fellow of the Royal Society (2020) CDD Award for her work on cell death (2016) Elected Fellow of Academy of Medical Sciences (FMedsci) (2013) Elected Supernumerary Fellow of Magdalen College, University of Oxford (2013) Elected Member of the European Molecular Biology Organisation (EMBO) (2011) Professor Lu has served on numerous scientific advisory boards, grant committees, and editorial boards. She has been a Medical Sciences Division Board Member at the University of Oxford since 2010, serves on the European Research Council (ERC) Consolidator Panel since 2012, and has been a Receiving Editor for Cell Death and Differentiation since 2014. Her leadership extends to organizing major international conferences, including multiple Sino-British Frontier Workshops of Cancer Biology and Ludwig-Nature Conferences on Nuclear Reprogramming of the Cancer Genome. Professor Lu leads a research group at the Ludwig Institute for Cancer Research, Oxford Branch, based at the Old Road Campus Research Building. Her team investigates tumor suppression mechanisms with particular focus on cellular plasticity and selective transcription. The laboratory has made significant contributions to understanding the ASPP family of proteins and their roles in cancer and developmental disorders. Professor Lu's group collaborates extensively with researchers across Oxford University and internationally, particularly with institutions in China.

Reinhard Lührmannمشاهده پروفایل

استاد

• Cellular Biochemistry
• RNA Splicing
• Structural Biology
• +۳ مورد دیگر

Reinhard Lührmann is a leading scientist in cellular biochemistry and RNA splicing. Since 1999, he has served as Director of the Department of Cellular Biochemistry at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany. He holds Honorary Professorships at both Philipps University of Marburg (since 2007) and Georg August University of Göttingen (since 2000). His research focuses on the structure and function of the spliceosome, a critical complex in RNA processing. Education: Dr. rer. nat. (Ph.D.) in Biochemistry, University of Münster (1975) Research Interests: Lührmann’s work explores the molecular mechanisms of RNA splicing, emphasizing the dynamic architecture of spliceosomes. His team uses advanced structural biology techniques like cryo-EM to elucidate the 3D organization of spliceosomal components and their interactions. This research has profound implications for understanding gene regulation and related diseases. Scientific Awards: Max Planck Research Prize (1990) Gottfried Wilhelm Leibniz Prize of the DFG (1996) Feldberg Prize (2002) Ernst Jung Prize for Medicine (2003) Member of EMBO, Leopoldina, and Academia Europaea Contributions: His publications highlight groundbreaking work in reconstituting spliceosomal processes and mapping their structural dynamics, contributing significantly to the field of molecular biology and RNA research.

Stephen Mojzsisمشاهده پروفایل

استاد

• Planetary Geochemistry
• Cosmochemistry
• Biogeodynamics
• +۶ مورد دیگر

Stephen Mojzsis is an Emeritus Professor at the University of Colorado Boulder and currently holds visiting or honorary professorships at several leading European institutions, including the University of Oslo (2024–2025), Eötvös Loránd University (ELTE) Budapest, and the University of Jena. He is a 2024 Member of Academia Europaea and a Humboldt Research Professor, recognized for seminal work in planetary geochemistry, cosmochemistry and the origins of life. Education: Ph.D. Geochemistry & Solid-State Physics, Scripps Institution of Oceanography, UC San Diego, 1997 M.A. Geology & Mineralogy, Boston University, 1992 B.A. Geology & Paleobiology, Boston University, 1988 Research Interests: Stephen Mojzsis integrates geochemistry, cosmochemistry and planetary science to understand the origin and early evolution of planets and life. His work spans the chemistry of the earliest Earth and Moon, sulfur-isotope tracers of Archean subduction, the composition of late-accreted material, and the mineralogical diversity of rocky exoplanets. He also explores prebiotic chemistry on Hadean Earth and early Mars, investigating how silicate glasses and hydrothermal systems could have facilitated RNA polymerization and the emergence of life. More broadly, he pursues Geoastronomy —linking stellar abundances in the solar neighborhood to the bulk compositions and long-term geodynamic evolution of terrestrial exoplanets, thereby constraining habitable environments across the Galaxy. Scientific Awards & Distinctions: Member, Academia Europaea (2024) Humboldt Research Prize, Alexander von Humboldt Foundation (2021–2024) Ida Pfeiffer Professorship, University of Vienna (2021) Fellow, Royal Society of Chemistry (2021) Fellow, Royal Astronomical Society (2021) Fellow, Geological Society of London (2021) Honorary Professor, ELTE Budapest (2022) External Member, Hungarian Academy of Sciences (2016) Fulbright Faculty Scholar (2007) ASSETT Outstanding Teacher Award, CU Boulder (2014) Advising & Funding: Between 2001 and 2023 Mojzsis supervised 8 PhD students, 6 post-doctoral researchers, 6 MSc and 5 BSc students. He has served on numerous grant panels including ERC Synergy and Advanced Grants, DFG Schwerpunkt Programme, NASA Exobiology, and NSF Graduate Research Fellowships. His research has been supported by the U.S. National Science Foundation, NASA, the European Research Council, the Humboldt Foundation, and other international agencies. Service & Leadership: From 2020–2023 he served as President of the Division of Planetary and Solar System Sciences of the European Geosciences Union. He is (or has been) an editorial board member for Geobiology , Astrobiology , Earth and Planetary Science Letters , Annales Geophysicae , and several other journals, and reviews for Nature and Science among more than 20 journals.

• Bioprocess Science
• Bioengineering
• Vaccine Development
• +۳ مورد دیگر

Fernando De Mathia is a researcher at the Institute of Bioprocess Science and Engineering, part of the Department of Biotechnology and Food Science at the University of Natural Resources and Life Sciences, Vienna (BOKU). His work focuses on bioprocess optimization, particularly in vaccine development and protein purification technologies. Research interests include bioprocess science, bioengineering, and downstream purification techniques for viral and recombinant protein-based therapeutics. His recent publications address continuous virus filtration and antibody purification processes, with applications in biopharmaceutical manufacturing. Key projects involve optimizing affinity-based RNA purification systems and continuous bioprocessing methods. He holds an M.Sc. degree and collaborates with international research teams on biotechnological innovations.

Müller Christophمشاهده پروفایل

استاد پژوهشی

• Protein crystallography
• RNA polymerase transcription
• Integrated structural biology
• +۴ مورد دیگر

Christoph Müller is a Research Professor leading the Structural and Computational Biology Unit at EMBL Heidelberg since 2007. He previously served as Deputy Head at EMBL Grenoble (2000-2007) and has been a Senior Scientist at EMBL since 2000. His research focuses on protein crystallography, RNA polymerase mechanisms, and integrated structural biology. Key contributions include studies on RNA polymerases I/III transcription, chromatin modifying complexes, and transcription factor interactions. Education: PhD in X-ray Crystallography & Biochemistry (1991), University of Freiburg MSc in Chemistry & Biochemistry (1986), University of Freiburg Postdoctoral training at Harvard University (1992-1995) and University of Freiburg (1991) His work bridges structural biology with functional mechanisms, employing cutting-edge techniques like cryo-EM and X-ray crystallography. Major achievements include solving the structure of the 14-subunit RNA polymerase I and elucidating promoter-opening mechanisms in RNA polymerase III. Awards: ERC Advanced Investigator Grant (2013) EMBO Membership (2005) Steinhofer Award (2003) His research group investigates transcriptional regulation at molecular and structural levels, with recent work exploring BET protein interactions and tRNA modification pathways. Collaborations span structural biology, epigenetics, and developmental biology.

Botond Roskaمشاهده پروفایل

استاد

• Gene therapy
• Eye
• Retina
• +۷ مورد دیگر

Botond Roska is a Professor at the Faculty of Science, University of Basel, Switzerland, and previously served as Professor at the Faculty of Medicine, University of Basel since 2014. He is the Founding Director of the Institute of Molecular and Clinical Ophthalmology Basel (IOB), established in 2018. His academic career includes serving as Senior Group Leader (2010-2019) and Junior Group Leader (2005-2010) at the Friedrich Miescher Institute in Basel. Born in 1969 in Hungary, Roska obtained his M.D. at the Semmelweis Medical School, a Ph.D. in neurobiology from the University of California, Berkeley, and studied genetics and virology as a Harvard Society Fellow at Harvard University and Harvard Medical School. Dr. Roska's research focuses on understanding the visual system at the level of cell types and circuits, with particular emphasis on the retina, thalamus, and cortex. His work aims to find ways to repair visual dysfunction and restore vision in blind individuals. He investigates how the organization of cell types and circuits in the nervous system, when combined with cellular engineering, can be used to design new therapies to fight blindness. Analysis of Roska's recent publications reveals a strong focus on single-cell resolution studies of the retina, development of gene therapy approaches for vision restoration, and detailed mapping of visual neural circuits. His work spans multiple disciplines including neuroscience, ophthalmology, genetics, and molecular biology, with a clear translational focus toward developing treatments for visual impairments. Dr. Roska has received numerous prestigious awards throughout his career: 1997: Fulbright Fellow 2001: Bearden Memorial Award for Biophysics 2002: Harvard Junior Fellow 2006: Marie Curie Excellence Grant 2009: EMBO Young Investigator 2010: ERC Starting Grant and VIVA Award 2011: Alcon Award and EMBO membership 2013: Alfred Vogt Award 2015: ERC Advanced Grant 2016: Cogan Award 2018: Bressler Prize and Alden W. Spencer Award 2019: Louis-Jeantet Prize, Order of Saint Stephen of Hungary, Cloëtta Prize, and Semmelweis Budapest Award 2020: ERC Advanced Grant and Körber European Science Prize 2024: Wolf Prize in Medicine (for sight-saving and vision restoration to blind people using optogenetics) As a principal investigator, Roska has secured significant research funding including multiple ERC grants (Starting Grant in 2010, Advanced Grants in 2015 and 2020), a Marie Curie Excellence Grant, and the VIVA Award. His laboratory has mentored numerous researchers who have gone on to publish impactful work in top-tier journals. The collaborative nature of his research is evident from the multi-institutional authorship of his publications. Dr. Roska founded and directs the Institute of Molecular and Clinical Ophthalmology Basel (IOB), which brings together basic scientists and clinicians to develop treatments for eye diseases. His laboratory employs advanced techniques including single-cell analysis, viral vector engineering, optogenetics, and neural circuit mapping to advance our understanding of the visual system and develop novel therapeutic approaches.

• microRNAs in diabetes
• Cytochrome P450/soluble epoxide hydrolase
• Platelet reactivity/platelet proteomics
• +۳ مورد دیگر

Ingrid Fleming is a Professor of Vascular Signalling and Director of the Institute for Vascular Signalling at Goethe University Frankfurt, Germany, where she has served since 2008. She also directs the Centre for Molecular Medicine at the same institution since 2010. Her research focuses on molecular mechanisms underlying vascular biology, diabetes-related vascular complications, and lipid mediator signaling. BSc in Pharmacology and Biochemistry (First Class Honours), Aston University (1988) PhD in Physiology, Université Louis Pasteur (1991) Habilitation in Physiology, Goethe University Frankfurt (1999) Fleming's work explores the role of cytochrome P450/soluble epoxide hydrolase pathways in vascular function, nitric oxide synthase regulation, and microRNA mechanisms in diabetes. She investigates how lipid mediators and oxidative stress impact endothelial dysfunction and vascular repair processes. Her publications demonstrate expertise in cardiovascular physiology, angiogenesis, and ischemic injury. Key themes include molecular regulation of endothelial cells, metabolic disorders in diabetes, and therapeutic targeting of epoxyeicosanoid pathways. Greenshield Award for Biochemistry (1988) Dr. Paul und Cilli Weill-Stiftung (1996) Servier Research Prize (1999) Heinz Meise-Preis (1999) Nitric Oxide Society Young Investigator Award (2000) Arthur Weber Prize (2002) Schunk-Preis for Medicine (2003) President, European Vascular Biology Organization (2010-2013) Member, German National Academy of Sciences (2016) As a Principle Investigator at the German Centre for Cardiovascular Research (since 2011), Fleming leads multidisciplinary research on vascular signaling. She has mentored numerous students and postdocs throughout her career at Goethe University, focusing on translational approaches to cardiovascular diseases. Her laboratories at the Centre for Molecular Medicine and Institute for Vascular Signalling integrate biochemical, molecular, and physiological techniques to study vascular homeostasis and pathology, with international collaborations including guest professorship at Huazhong University (2018-2021).

Anne Ephrussiمشاهده پروفایل

استاد

• Developmental Biology
• RNA transport
• Localized translation
• +۳ مورد دیگر

Anne Ephrussi is a distinguished researcher and leader at the European Molecular Biology Laboratory (EMBL), where she has served as Head of the Developmental Biology Unit since 2007. She also coordinated the EMBL International Center for Advanced Training (EICAT) starting in 2005 and previously served as Dean of Graduate Studies for the EMBL International PhD programme from 2005-2008. Her career at EMBL spans over three decades, beginning as a Group Leader in 1992 and progressing through increasingly significant leadership roles. Dr. Ephrussi's educational background includes: PhD from Massachusetts Institute of Technology (1985) Postdoctoral work at Harvard University Postdoctoral fellowship at the Whitehead Institute, MIT Her research focuses on fundamental mechanisms of developmental biology, particularly RNA transport and localized translation. She has made seminal contributions to understanding how mRNA localization controls embryonic patterning in Drosophila , with her work on the oskar gene representing landmark discoveries in the field. Her research integrates molecular, cellular, and genetic approaches to investigate how spatial regulation of gene expression establishes body patterns during development. Analysis of her publication record reveals consistent contributions to understanding RNA localization mechanisms, with particular emphasis on Drosophila oogenesis and embryogenesis. Her work spans molecular characterization of RNA-protein interactions, cytoskeletal transport mechanisms, translational control, and the coupling of nuclear processing with cytoplasmic mRNA localization. The progression of her research shows increasing sophistication in methodology while maintaining focus on fundamental questions of developmental patterning. Her distinguished career has been recognized with numerous prestigious awards: 2024 Member, German National Academy of Sciences (Leopoldina) 2015 Chevalier de la L\u00e9gion d'Honneur 2011 Chevalier dans l'Ordre National du M\u00e9rite 2010 Member of the Academia Europaea 2008 Elected member French Acad\u00e9mie des Sciences 2000 International Union of Biochemistry and Molecular Biology, E.C. Slater Lecture 1995 Elected member European Molecular Biology Organisation (EMBO) As Dean of Graduate Studies for the EMBL International PhD programme and through her leadership of the Developmental Biology Unit, Dr. Ephrussi has played a significant role in mentoring and training the next generation of scientists. Her laboratory has been consistently supported by competitive research funding, enabling her team to pursue innovative approaches to understanding developmental mechanisms. She has established EMBL as a major center for research in RNA biology and developmental genetics. At EMBL Heidelberg, Dr. Ephrussi leads the Developmental Biology Unit, which investigates the origin, development, and evolution of organisms. Her laboratory has been instrumental in developing approaches to study mRNA localization and translational control in the context of developmental patterning, creating a vibrant research environment that attracts scientists from around the world.

• Molecular Oncology
• Cancer Genetics
• Genetic Predisposition to Cancer
• +۴ مورد دیگر

Edith Olah is a Professor of Molecular Genetics and Head of the Department of Molecular Genetics at the National Institute of Oncology in Budapest, Hungary. She holds additional roles as Invited Professor at Eötvös Lorand University and Human Geneticist (h.c.) at Haynal Imre Postgraduate Medical School, reflecting her interdisciplinary expertise in cancer genetics and molecular oncology. PhD in Genetics (Eötvös Lorand University, 1974) D.Sc. in Molecular Cell Biology and Oncology (Hungarian Academy of Sciences, 1992) Member of the Hungarian Academy of Sciences (2007) Her research focuses on molecular mechanisms of oncogenesis, cancer susceptibility genes in Central-Eastern Europe, and metabolic reprogramming in tumors. She has contributed to landmark studies on BRCA1/2 mutations and Lynch syndrome, with over 4,000 citations and an H-index of 37. Her work spans genetic testing for inherited cancer risks and international collaborations like CIMBA and IBCCS. Scientific honors include Fellow of the European Academy of Cancer Sciences (2009), AACR Plaque for International Leadership (2003), and multiple European cancer research awards. She has supervised 10 PhD theses and trained 13 visiting scientists from 6 countries.

Marat Yusupovمشاهده پروفایل

استاد پژوهشی

• Molecular Biology
• Structural Biology
• Ribosome Research
• +۴ مورد دیگر

Marat Yusupov is a Research Professor at the Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) in Strasbourg, France, where he has served as Directeur de Recherche du C.N.R.S. (class 1) since 2010. Previously, he held research positions at IGBMC/IBMC from 2000-2010 and was a Research Associate Biologist at the University of California, Santa Cruz from 1996-2000. His research focuses on ribosome structure and function. Dr. Yusupov's research interests span multiple areas of molecular and structural biology with emphasis on: Ribosome structure in bacteria and yeast Mechanisms of protein synthesis Regulation of translation processes Crystallography and cryo-EM of macromolecular complexes His publication record demonstrates consistent focus on ribosome structure and function over two decades. His research has evolved from foundational work on ribosome crystallography to increasingly sophisticated studies of eukaryotic ribosomes using advanced structural techniques. The research trajectory shows progression from basic structural characterization to mechanistic understanding of translation processes at atomic resolution. Dr. Yusupov has received numerous prestigious awards for his contributions to science: 2001: AAAS Newcomb-Cleveland Prize 2011: Grand Prix Emile Jungfleisch of French Academy of Sciences 2012: Gregori Aminoff Prize of Swedish Academy of Sciences 2012: Silver Medal from CNRS 2012-2016: ERC grant funding As a principal investigator at IGBMC, Dr. Yusupov has secured significant research funding including a European Research Council grant that supported his team's work from 2012-2016. His laboratory has been instrumental in advancing structural understanding of ribosomes, particularly through the integration of crystallography and cryo-EM techniques. Dr. Yusupov leads a research team at IGBMC focused on ribosome structure and function. His laboratory has made significant contributions to understanding the molecular mechanisms of protein synthesis, with particular emphasis on the structural basis of translation processes in both prokaryotic and eukaryotic systems.

Mihaela Zavolanمشاهده پروفایل

استاد

• Computational RNA Biology
• Bioinformatics
• Systems Biology
• +۵ مورد دیگر

Mihaela Zavolan is a Full Professor at the Biozentrum, University of Basel, Switzerland, where she has held continuous faculty appointments since 2003 (Assistant Professor 2003-2008, Associate Professor 2008-2014, Full Professor 2014-present). She simultaneously serves as a Group Leader at the Swiss Institute of Bioinformatics since 2004, directing research on RNA regulatory networks. Her educational background includes: PhD in Computer Science, University of New Mexico (1996-1999) M.Sc. in Computer Science, University of New Mexico (1994-1996) M.D., University of Medicine and Pharmacy, Timisoara, Romania (1986-1992) Dr. Zavolan's research centers on computational RNA biology , with pioneering work in microRNA mechanisms, RNA splicing, RNA-binding proteins, and pre-mRNA 3' end processing. Her group integrates advanced computational modeling with high-throughput experimental data to dissect post-transcriptional gene regulation networks. Key methodological contributions include quantitative analysis of CLIP techniques and biophysical models of miRNA-mRNA interactions. Analysis of her publication record reveals consistent focus on developing and applying computational frameworks for RNA regulatory networks, with increasing emphasis on genome-wide mapping of RNA-protein interactions and quantitative modeling of regulatory dynamics. Her work bridges molecular biology, genomics, and systems biology through innovative algorithm development. Her major scientific awards include: ERC Starting Grant (2012) Young Investigator of EURASNET (2006-2009) Lita Annenberg Hazen Presidential Fellowship, The Rockefeller University (2001-2003) Presidential Fellowship, The Rockefeller University (2001) Burroughs Wellcome Fellow, The Rockefeller University (2000) Dr. Zavolan has secured competitive research funding including the ERC Starting Grant and maintains active grant support through her group leadership positions. She serves on editorial boards of Genome Biology, Bioinformatics, BMC Molecular Biology, and Cells, and has organized major conferences including the European Conference on Computational Biology (2012) and Computational RNA Biology Conference (2014). She leads parallel research groups at the Biozentrum (Computational and Systems Biology) and Swiss Institute of Bioinformatics (RNA regulatory networks), employing interdisciplinary teams that combine computational biology, molecular biology, and high-throughput data analysis to investigate RNA-mediated gene regulation mechanisms.