جست‌وجوی استاد و پژوهشگر

• Neurogenetics
• Inherited Peripheral Neuropathies
• Genetic Linkage Analysis
• +۴ مورد دیگر

Professor Marina Kennerson is a leading academic at the University of Sydney , affiliated with the Faculty of Medicine and Health and the School of Medical Sciences . She serves as Director of the Northcott Neuroscience Laboratory (ANZAC Research Institute), Principal Hospital Scientist at Concord Hospital's Molecular Medicine Laboratory, and Deputy Director (Research) for the Sydney Local Health District Institute of Precision Medicine and Bioinformatics. Her work focuses on Neurogenetics , particularly identifying causative genes for Inherited Peripheral Neuropathies (IPN), with over 25 years of experience in the field. Research Interests Gene discovery for IPN using genetic linkage and next-generation sequencing Functional genomics via iPSC-derived motor neurons and C. elegans models Transition of genomic technologies to clinical neurogenetic testing Leadership in global consortia like the Peripheral Nerve Society and Asian Oceanic Inherited Neuropathy Consortium Scientific Contributions Her research program integrates multiomics approaches with AI tools to analyze genomic data. She has identified 10 causative IPN genes and two structural variation mutations (DHMN1 and CMTX3), advancing pre-clinical modeling and therapeutic development. Her lab's work has established Concord Hospital as a reference center for IPN testing in Australia. Collaborations International partnerships include collaborations with: University of Malaya (Malaysia) – Dr. Azlina Ahmad-Annuar and Dr. Nortina Shahrizaila University of Miami (USA) – Professor Stephan Zuchner

Mohammed El-Kebirمشاهده پروفایل

دانشیار

• Cancer Genomics
• Computational Biology
• Combinatorial Optimization
• +۴ مورد دیگر

Mohammed El-Kebir is an Associate Professor in the Department of Computer Science at the University of Illinois at Urbana-Champaign (UIUC) , with affiliate appointments in Electrical & Computer Engineering, the Institute of Genomic Biology, and the National Center for Supercomputing Applications. His research focuses on combinatorial optimization algorithms for fundamental challenges in cancer genomics and computational biology , particularly tumor phylogenetics , single-cell sequencing data analysis , and metastasis migration history modeling . PhD in Computer Science, Centrum Wiskunde & Informatica (Netherlands) and VU University Amsterdam (2015) Postdoctoral training at Brown University and Princeton University (2014-2017) El-Kebir's work addresses intra-tumor heterogeneity by developing mathematical models to reconstruct evolutionary trees of cancer mutations from mixed sequencing data. His lab has pioneered methods like SPhyR and MACHINA for phylogeny inference under data limitations, and PhyDOSE for optimizing single-cell sequencing experiments. His research bridges computational challenges with clinical implications for personalized medicine and therapy resistance prediction . Key contributions include: Theoretical foundations for cancer phylogenetic problems (hardness proofs, algorithm design) Single-cell sequencing algorithms accounting for data sparsity and errors Migration graph frameworks for metastasis analysis Interactive tools like ClonArch and CNAViz for tumor data visualization El-Kebir has received multiple accolades including the NSF CAREER Award (2021) and CRII Award (2019) . His group has produced 15+ peer-reviewed publications since 2020, with student collaborators securing prestigious fellowships like the NSF GRFP . He actively contributes to conference program committees (RECOMB, ISMB, WABI) and teaches graduate-level courses in Bioinformatics and Computational Cancer Genomics .

Fan Yuanمشاهده پروفایل

استاد

• Drug Delivery
• Gene Delivery
• Vaccine Development
• +۷ مورد دیگر

Dr. Fan Yuan is a Professor of Biomedical Engineering and Ophthalmology at Duke University and a Member of the Duke Cancer Institute . His research focuses on transport analysis in drug and gene delivery , cell and tissue biomechanics , and electric field-mediated gene delivery for cancer and ocular disease therapy. Ph.D. in Biomedical Engineering from City University of New York (1990) B.S. and M.S. in Physics from Peking University (1983, 1985) Research Interests: Drug, gene, and vaccine delivery systems Pharmacokinetics and transport barriers Electroporation and electrotransfer technology Tumor pathophysiology and ocular delivery Nanoparticle and macromolecule transport Scientific Contributions: Over 100 peer-reviewed publications Author of a textbook on Transport Analysis in Biological Systems Developed models for tumor microvasculature and ocular drug transport Scientific Awards: Fellow, American Institute for Medical and Biological Engineering (2007) National Science Foundation CAREER Award (2000) SPORE in Breast Cancer Career Development Award (1996) IPM Innovative Instrumentation Awards (1993, 1994) Dr. Yuan’s recent work emphasizes acoustofluidic devices for targeted drug delivery, lysosomal function modulation in vaccine efficiency, and biomechanical analysis of trabecular meshwork in glaucoma research.

Laura Spagnoloمشاهده پروفایل

استاد

• Structural Biology
• Genome Editing
• DNA Repair
• +۳ مورد دیگر

Laura Spagnolo is Professor of Biophysical Chemistry in the Molecular Biosciences department at the University of Glasgow and Group Leader at the Research Complex at Harwell. She co-founded the Scottish Centre for Macromolecular Imaging and leads research on genome editing mechanisms using integrated structural biology approaches. She holds an MSc in Pharmacy from the University of Trieste and a PhD from the University of Padova/EMBL Heidelberg. Her research focuses on: Structural mechanisms of CRISPR systems and DNA repair complexes Macromolecular assemblies in genome editing and RNA metabolism Multi-scale structural analysis from atomic to cellular resolution Her publications demonstrate consistent focus on structural biology of DNA/RNA-processing complexes, with recent work emphasizing CRISPR machinery, DNA repair systems, and archaeal biology using cryo-EM and biochemical approaches. Active grants include: BBSRC funding for Staufen protein microscopy (2024-2027) MRC support for electron microscopy modernization (2022-2023) BBSRC project on DNA recombinases (2022-2025) Scottish Funding Council grants for macromolecular imaging (2018-2021) She directs the Spagnolo research group studying genome engineering complexes and collaborates with the Scottish Macromolecular Imaging Centre.

Ryan S. Grayمشاهده پروفایل

دانشیار

• Musculoskeletal Disease
• Developmental Biology
• Genetics
• +۴ مورد دیگر

Ryan S. Gray, Ph.D. is an Associate Professor in the Department of Pediatrics at The University of Texas at Austin , with an adjunct faculty appointment in the Department of Nutritional Sciences within the College of Natural Sciences . Education: Ph.D. in Cellular and Molecular Biology from UT Austin Postdoctoral Training: Washington University School of Medicine Gray's research focuses on musculoskeletal diseases , particularly adolescent idiopathic scoliosis (AIS) and cartilage degeneration . His lab employs a multi-tiered approach combining zebrafish , mouse , and cell culture models informed by human genomics to uncover mechanisms of spine development and disease. Key areas include: Genetic regulation of spine morphogenesis Role of cilia in cerebrospinal fluid dynamics Protein assembly in vertebrate evolution ADGRG6 and SOX9 signaling in cartilage homeostasis His publications highlight novel genetic pathways in AIS, including Kif6 , Inppl1a , and dysregulated dynein genes . Awards include the Early Investigator Podium Award (2017) and Best Poster Award (2015) from leading orthopedic societies. Gray leads the Gray Lab , which emphasizes translational research for musculoskeletal disorders. The lab's work spans from basic science (e.g., kinesin motor proteins) to clinical applications in scoliosis diagnosis and treatment.

Olga Zhaxybayevaمشاهده پروفایل

دانشیار

• Microbial Evolution
• Bioinformatics
• Computational Genomics
• +۴ مورد دیگر

Olga Zhaxybayeva is an Associate Professor of Biological Sciences and Adjunct Associate Professor of Computer Science at Dartmouth College. She is a Simons Foundation Investigator in Mathematical Modeling of Living Systems, focusing on microbial evolution and bioinformatics. B.S. in Applied Mathematics (Kazakh State University, 1997) Ph.D. in Genetics (University of Connecticut, 2004) Postdoctoral Training in Microbial Evolution (Dalhousie University, 2005-2009) Her research explores how microbes evolve through horizontal gene transfer, genomic signatures of adaptation, and computational modeling of microbial systems. She investigates gene transfer agents (GTAs) as viriforms and thermoadaptation in Thermotogota phylum. Her recent articles highlight GTAs' co-evolution with stress response genes, thermoadaptation genetics, and computational methods for detecting horizontal gene transfer. These works span microbiology, evolutionary genetics, and bioinformatics. Scientific Awards Simons Foundation Investigator in Mathematical Modeling of Living Systems She has trained 16 students/postdocs and received 5 grants. Her lab at Life Sciences Center Room 333 Hanover, NH, collaborates internationally on microbial genome analysis and systematics.

Seval TÜRKمشاهده پروفایل

استادیار

• Histology and Embryology
• Immunohistochemistry
• Lectin Histochemistry
• +۲ مورد دیگر

Seval TÜRK serves as an Assistant Professor in the Department of Basic Sciences at the Faculty of Dentistry, Antalya Science University since 2020. Her research integrates histological, embryological, and tissue engineering approaches with expertise in lectin histochemistry and stem cell applications. Educational background: Bachelor's in Biology, Süleyman Demirel University Faculty of Science and Literature (2008) Master's Degree, Süleyman Demirel University (2008-2010) Ph.D., Süleyman Demirel University (2011-2015) Second Doctorate in Stem Cell and Tissue Engineering, İstinye University (2022-present, thesis stage) Dr. TÜRK's research focuses on structural tissue analysis using advanced histochemical techniques, with significant contributions to gastrointestinal histology, salivary gland pathology, and reproductive tissue dynamics. Her work examines glycoconjugate distributions, endoplasmic reticulum stress mechanisms, and stem cell applications across diverse animal models. Current investigations explore natural compounds' therapeutic potential against diabetic complications and environmental stressors' impacts on organ systems. Analysis of her 2022-2025 publications reveals consistent methodological rigor in lectin histochemistry and immunohistochemistry, with increasing emphasis on stem cell integration. Key thematic clusters include: 1) Chemical compound effects (cinnamic acid, acetyl L-carnitine) on tissue pathology, 2) Electromagnetic field and toxin impacts on cellular structures, and 3) Developmental biology of mammary glands and reproductive tissues. Scientific recognition: No specific awards documented in source materials Dr. TÜRK actively contributes to departmental quality assurance processes and institutional committees. Her extensive publication record indicates successful research project leadership and likely graduate student mentorship, though specific advisee details remain unreported. Current activities include dual institutional engagement between Antalya Science University and İstinye University's stem cell research programs. Her laboratory work centers on histochemical analysis of animal tissue models, particularly rodents and avian species, with recent expansion into stem cell applications through her ongoing doctoral research.

Edoardo Sozziمشاهده پروفایل

پژوهشگر ارشد

• Neuroscience
• Neurobiology
• Stem Cell Research
• +۶ مورد دیگر

Edoardo Sozzi is a Visiting Research Fellow and PhD student at Lund University's Faculty of Medicine, specializing in the Developmental and Regenerative Neurobiology group under Prof. Malin Parmar. He earned a BSc in Biotechnology (2018) and a dual MSc in Neuroscience (2020) from the University of Pisa and Scuola Normale Superiore, Italy. His research focuses on the development, functionality, and diversity of human dopaminergic neurons using 3D cell culture systems like brain organoids and xenograft models, with heavy reliance on single-cell RNA sequencing. His work intersects neuroscience, developmental biology, and regenerative medicine, targeting neurodegenerative disorders such as Parkinson's disease. Key publication trends include innovations in organoid technology , single-cell transcriptomics , and WNT signaling modulation . He has contributed to 11 scientific outputs , including a 2025 doctoral thesis, peer-reviewed articles in Nature Methods and Development , and a 2023 Horizon Europe grant (OpenMIND project) for opto-electronic neural modeling in neurodegenerative diseases. Sozzi actively participates in academic events, organizing conferences like Neuroscience Day 2024 and UniStem Day 2024 , and serves as a presenter in multidisciplinary initiatives (MultiPark). His work aligns with UN Sustainable Development Goals for Medical and Health Sciences and Neurosciences .

Hawa Racine Thiamمشاهده پروفایل

استادیار

• Biophysics
• Cell Biology
• Immunology
• +۵ مورد دیگر

Hawa Racine Thiam is an Assistant Professor of Bioengineering and Microbiology & Immunology at Stanford University , where she holds appointments in the Bio-X, Maternal & Child Health Research Institute (MCHRI), and Sarafan ChEM-H. Her research integrates microscopy , microfabrication , and quantitative cell biology to study the cellular biophysics of immune cells , particularly NETosis - a neutrophil-mediated pathogen-trapping mechanism with implications in both infection and sterile inflammation. Ph.D. in Biophysics from Institut Curie/Paris Descartes University (2014) Postdoctoral training in Quantitative Cell Biology at National Institutes of Health (2022) Co-inventor of microfabricated devices for cellular mechanics analysis Her lab's publications reveal trends in nuclear deformation mechanics , cytoskeletal dynamics , and RNA-protein complexes in autoimmunity . Key techniques include high-resolution time-lapse microscopy , mechanical modeling , and microenvironment engineering . Chan Zuckerberg Biohub Investigator (2022-2027) Esther Ehrman Lazard Faculty Scholar (2022-2025) ASCB Porter Prize Honorable Mention (2020) NIH Fellow Award (2019) As a mentor, she serves as Doctoral Dissertation Advisor and Postdoctoral Faculty Sponsor , guiding students in Bioengineering , Biophysics , and Immunology Ph.D. programs. Her work at Stanford's HR Thiam Lab aims to engineer innate immune cells for enhanced host defense while mitigating pathological inflammation through mechanobiological insights.

Janna Hastingsمشاهده پروفایل

استادیار

• Medical Knowledge Systems
• Artificial Intelligence in Healthcare
• Ontology Development
• +۴ مورد دیگر

Janna Hastings is Assistant Professor for Medical Knowledge and Decision Support at the Institute for Implementation Science in Health Care (Faculty of Medicine) at the University of Zurich since August 2022, while also serving as Vice-Director of the School of Medicine at the University of St. Gallen. Her research focuses on digitalization in clinical contexts, examining how AI-driven knowledge systems reshape clinical practice, professional identity, and doctor-patient relationships. Education: PhD in Computational Biology (University of Cambridge, 2019), part-time MSc in Computer Science (University of South Africa, 2011), MSc in Philosophy (Open University, 2012) Prior Roles: Group Coordinator at European Bioinformatics Institute (2006-2015), Postdoctoral Researcher at Otto-von-Guericke University Magdeburg (2019-2022), Co-Leader of Human Behaviour-Change Project at University College London (2017-2022) Her research spans ontology development for biomedical domains (ChEBI, Human Behaviour Ontology), AI applications in healthcare decision-making, and behavior change interventions. Key projects include: Building ChEBI molecular ontology Developing Human Behaviour-Change Project knowledge system Ontology-driven mental health frameworks LLM applications in radiation oncology Time-series modeling of metabolism in ageing She explores the capabilities and limitations of clinical AI systems, with publications in JMIR and Lancet Digital Health , covering topics like bias prevention in generative AI and proteomic biomarker discovery. Her work bridges biomedical research with implementation science and digital ethics.

Jessica Larsenمشاهده پروفایل

دانشیار

• Biomaterials
• Drug Delivery
• Blood-Brain Barrier
• +۱۲ مورد دیگر

Jessica Larsen is the Carol and John ’63 Cromer Family Endowed Associate Professor in the Department of Chemical and Biomolecular Engineering at Clemson University. She holds a BS (2012) and PhD (2017) in Chemical Engineering from the University of Virginia and Auburn University, respectively. Research Focus: Polymeric biomaterials for blood-brain barrier (BBB) penetration in neurotherapeutics Key Techniques: Enzyme-responsive polymersomes, gene editing delivery, disease-specific stimuli response Disease Targets: Parkinson’s disease, GM1 gangliosidosis, glioblastoma, peripheral nerve injuries Publications highlight advancements in CRISPR-Cas9 delivery MRI contrast agents RNA biology in neural repair Autophagy modulation BBB bypass strategies Awards include: Phil and Mary Bradley Award for Mentoring in Creative Inquiry 2021 Outstanding Faculty Woman at Clemson University NSF CAREER Award (2021) 2022 South Carolina Governor’s Young Scientist Award Advisees include PhD candidates E. Bagwell, M. Shin, N. Henkel, and D. Migliaccio, who contribute to her lab’s work on BBB-targeted therapies. Lab: The Larsen Lab (www.thelarsenlab.com) specializes in nanotherapeutic strategies for central nervous system disorders, with a focus on polymer-based delivery systems.

• Functional Genomics
• Non-coding Genome Analysis
• Developmental Genomics
• +۳ مورد دیگر

Julia Metzger is a Research Group Leader at the Max Planck Institute for Molecular Genetics in Berlin, heading the Heisenberg Research Group Veterinary Functional Genomics . Her group investigates the genetic architecture of mammalian genomes, focusing on non-coding variations and their role in genotype-phenotype relationships , particularly through multi-omics approaches and high-throughput sequencing . Her research integrates computational genomics with experimental biology to study structural variations in pigs and horses, such as body size determination and curly hair phenotypes . Current projects include the Heisenberg-funded MEASURE initiative on regulatory genetics in growth biology. Recent publications highlight her expertise in transcriptome analysis , evolutionary genomics , and veterinary genetics , with co-authorship on studies involving equine , porcine models , and lemur population dynamics . She mentors students like Nima Khaveh (PhD, 2025) and Ward Al Raei (Master’s, 2024), who explore polyploid genomics and tandem repeat genotyping . Awards include the DFG Heisenberg grant .

Sutapa Chakrabartiمشاهده پروفایل

پژوهشگر

• Post-transcriptional Gene Regulation
• mRNA Degradation Pathways
• RNA Binding Proteins
• +۳ مورد دیگر

Sutapa Chakrabarti is a Group Leader at the Biochemistry Department, Freie Universität Berlin , focusing on mRNA metabolism and post-transcriptional gene regulation . Her research investigates how cis-acting signals in mRNA interact with protein factors to direct transcripts toward specific degradation pathways , using biochemical and structural approaches . Current Research: Elucidating mechanisms of mRNA decay via Nonsense-Mediated Decay (NMD) , ARE-mRNA decay , and Staufen-mediated decay . Funding: Supported by the German Research Foundation (DFG) and Freie Universität Berlin research commission . Recent Publications: 2025 study on MOV10 helicase in NMD, 2024 analysis of SARS-CoV-2 N protein’s role in mRNA decay, and 2022 work on UPF1-UPF2 interactions.

Michael Krahnمشاهده پروفایل

استاد

• biomolecular label chemistry
• RNA biochemistry
• bioorthogonal chemistry
• +۷ مورد دیگر

Michael Krahn is a University Professor at the University of Münster's Faculty of Medicine, where he leads the Medical Cell Biology research group within Medical Clinic D - Internal Medicine. Holding dual doctorates in Veterinary Medicine and Natural Sciences, he maintains an active research program focusing on molecular mechanisms of cell biology with particular emphasis on membrane dynamics and cellular structures. His research interests span biomolecular label chemistry, RNA biochemistry, bioorthogonal chemistry, RNA modifications, nucleic acid chemistry, chemical biology, and mRNA. Professor Krahn's work particularly explores how phosphoinositide lipids regulate cell polarity and membrane organization, with significant contributions to understanding slit diaphragm formation, endocytosis, and related disease mechanisms. His publication record shows consistent research output through 2023, with recent work examining tight junction formation, ER stress responses in podocytes, Hippo pathway regulation, and SEC61A1 variants in liver disease. These publications demonstrate his interdisciplinary approach bridging cell biology, molecular medicine, and disease pathology, primarily using Drosophila models and mammalian cell systems. Professor Krahn participates in the "Cells in Motion" collaborative research initiative and is a member of the Imaging Network, focusing on microscopy applications for cellular dynamics research. His work appears in high-impact journals including Nature Communications, Cell Reports, and Journal of the American Society of Nephrology, reflecting the significance of his contributions to cell polarity and membrane biology fields.

Kuberan Balagurunathanمشاهده پروفایل

استاد

• Glycobiology
• Proteoglycan Biology
• Glycosaminoglycan (GAG) Biosynthesis
• +۳ مورد دیگر

Kuberan Balagurunathan is a Professor of Medicinal Chemistry at the University of Utah, affiliated with the Biological Chemistry Program. His research focuses on glycosaminoglycan (GAG) biosynthesis and proteoglycan biology, developing chemical tools to understand heparan sulfate interactions. Education: B.S. from St. Joseph's College, India; Ph.D. from University of Iowa Research interests center on GAG biosynthetic pathways , heparan sulfate structural analysis , and click-xyloside applications . Key work includes the GAGOSOME model for dynamic biosynthesis regulation and enzymatic synthesis of defined GAG structures. Recent publications highlight microbial production of heparosan, bioinformatics tools for RNA analysis, and nanosensor development for pharmaceutical contaminants. These works span molecular engineering, structural glycobiology, and biomedical informatics.