RNA Modifications Professors and Supervisors in Germany | ApplySharif

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جست‌وجوی استاد و پژوهشگر

استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۱-۱۵ از ۲۷۶ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Waldemar Kolanusمشاهده پروفایل

استاد

Rhenish Friedrich Wilhelm University of BonnGermany

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

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Konstantinos Anastassiadisمشاهده پروفایل

استاد

Dresden University of TechnologyGermany

Konstantinos Anastassiadis is a Professor at the Center for Molecular and Cellular Bioengineering (CMCB) of Dresden University of Technology , leading the Stem Cell Engineering group at the Biotechnology Center (BIOTEC) . His research focuses on unraveling molecular pathways regulating stem cell self-renewal and lineage commitment, with a strong emphasis on genetic engineering tool development and epigenetic mechanisms during cellular reprogramming. The lab utilizes mouse and human embryonic stem cells, neural stem cells, mesenchymal stromal cells, and induced pluripotent stem cells (iPSCs) in their investigations. Core Research Areas: Molecular regulation of stem cell fate Epigenetic mechanisms (e.g., UTX/UTY histone demethylases) Genetic engineering tool development (Flp, Dre, Vika recombinases, CRISPR protocols) Conditional immortalization systems for rare cell expansion Publications highlight his contributions to understanding: Role of histone methyltransferases (MLL1, MLL2, Setd1b) in hematopoiesis and cancer Epigenetic regulation during mouse development and spermatogenesis Genetic tools for protein tagging, transposon-mediated BAC transgenesis Interactions between stem cells and niche microenvironments Transcriptional and mechanical markers during reprogramming Collaborations span immunology , developmental biology , and bioinformatics . The lab actively participates in teaching activities at CMCB and maintains a focus on translational applications of stem cell research.

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Oliver Seitzمشاهده پروفایل

استاد

Humboldt UniversityGermany

Prof. Oliver Seitz leads the Bioorganic Synthesis research group at the Department of Chemistry, Faculty of Mathematics and Natural Sciences, Humboldt University of Berlin. His lab focuses on cutting-edge chemical biology approaches for protein/nucleic acid interrogation, with recent work advancing DNA/RNA-programmed assemblies for cellular imaging and therapeutic applications. Research spans chemical protein synthesis, glycoprotein/phosphoprotein engineering, and nucleic acid-templated reactions. Key innovations include Forced Intercalation (FIT) probes for wash-free RNA imaging, loss-of-affinity principles for catalytic efficiency, and peptide-PNA conjugates for targeted cellular delivery. The group actively develops tools for live-cell protein labeling and biomolecular spatial screening. Recent publications (2021-2024) emphasize fluorescence-based detection systems, catalytic templated reactions, and therapeutic peptide synthesis. Trends show increasing sophistication in multi-dye probes, glycan engineering, and RNA-triggered pro-drug activation. Scientific awards include: Max Bergmann Award (2019) Prof. Seitz actively advises doctoral students, with recent graduates Marvin Björn Stutz (2023, magna cum laude ), Dino Gluhacevic von Krüchten (2023, summa cum laude ), and Sophie Schöllkopf (2023, magna cum laude ). Current PhD candidates include Ekaterina Kazakova (glycoprotein synthesis), Alina Herfort (phosphoproteins), and Lina-Marie Beck (peptide-nucleic acid conjugates), with postdocs like Dr. Mandana Oloub (viscosity sensors). The Bioorganic Synthesis lab operates within Berlin's vibrant chemical research ecosystem, utilizing specialized techniques for chemical protein synthesis and nucleic acid detection. Recent team growth reflects ongoing projects in RNA imaging, catalytic templated reactions, and therapeutic conjugate development, supported by open positions for new researchers.

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Susanne Foitzikمشاهده پروفایل

استاد

University of MainzGermany

Prof. Dr. Susanne Foitzik is a Professor of Evolutionary Biology at Johannes Gutenberg University Mainz since 2010, where she leads the Evolution & Behavioral Ecology of Ants research group at the Institute of Organismic and Molecular Evolution (IOME). Previously, she was Professor in Behavioral Ecology at LMU Munich (2004-2010) and Assistant Professor in Zoology at the University of Regensburg (2000-2004). She earned her PhD in Biology from Julius Maximilian University, Würzburg in 1998. Her research integrates approaches from behavioral ecology through genomics to epigenetics, focusing on ants as model organisms to study complex social behaviors. Host-parasite coevolution and social parasitism in ants Molecular mechanisms underlying division of labor Reversal of the fecundity-longevity trade-off in social insects Gene regulation in phenotypic plasticity Evolution of chemical communication systems Analysis of her recent publications (2022-2025) reveals a strong focus on molecular mechanisms of social behavior, with particular emphasis on host-parasite interactions, epigenetic regulation of behavior, and genomic adaptations in social insects. Her work increasingly combines transcriptomic, proteomic, and functional genomic approaches to understand the molecular basis of social evolution. Among her notable scientific achievements: Speaker of Research Training Group 2626 GenEvo: Gene Regulation in Evolution (2019-present) Speaker of EES Master Program funded by VW foundation (2007-2010) DAAD Fellow at State University of New York (1992-93) Prof. Foitzik has supervised numerous PhD students and postdocs, including Maide Macit, Tom Sistermans, and Marcel Caminer. Her research is supported by multiple DFG-funded projects investigating host-parasite coevolution, the role of gene regulation in division of labor, and parasite interference in host gene expression. She serves as Handling Editor for Biology Letters and previously served on the editorial board of Insectes Sociaux. Her research group operates within the Institute of Organismic and Molecular Evolution (IOME) at Mainz, with laboratory facilities at the Biozentrum I. The group collaborates extensively with researchers across Germany and internationally, including partnerships with institutions in Frankfurt, Freiburg, Bristol, and Tel Aviv.

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Andrew Bassettمشاهده پروفایل

پژوهشگر

Leibniz Institute for Zoo and Wildlife ResearchGermany

Dr. Andrew Bassett serves as Head of the Cellular and Gene Editing Research group at the Wellcome Sanger Institute, where he develops cutting-edge genome engineering techniques using human pluripotent stem cells to investigate neurodegenerative diseases including Alzheimer's and Parkinson's. His work focuses on scaling genetic screening approaches and improving CRISPR specificity for modeling complex disease mechanisms. His academic training includes: PhD at the MRC Laboratory of Molecular Biology (MRC-LMB) with Andrew Travers on chromatin remodelling in heterochromatin formation Postdoctoral research with David Baulcombe at the University of Cambridge studying small RNA roles in chromatin modification Additional postdoctoral work with Chris Ponting at the MRC Functional Genomics Unit (MRC-FGU) in Oxford, where he pioneered CRISPR applications in Drosophila Bassett's research program centers on developing advanced genome engineering methodologies for precise modulation of gene expression networks during development and neurodegeneration. His group specializes in creating complex editing events (SNPs, paired knockouts, enhancer perturbations) within iPSC-derived models, with particular emphasis on epigenetic regulation and transcriptional control. Current projects integrate single-cell 'omics and phenotypic assays to decode genetic causes of neurodegenerative disorders through the OpenTargets consortium. Analysis of his 15 most recent publications reveals dominant trends in CRISPR technology development (35%), neurodegenerative disease modeling (30%), and single-cell functional genomics (25%). His work consistently bridges methodological innovation with disease mechanism studies, increasingly incorporating multi-omics approaches and expanding into cancer immunology and infectious disease applications since 2022. As group leader, Bassett mentors postdoctoral researchers and PhD students while securing major funding for genome engineering initiatives. His team operates within the Sanger Institute's Cellular Operations division and maintains critical partnerships with the OpenTargets consortium for therapeutic target validation. The laboratory specializes in high-throughput screening platforms using iPSC-derived neural and microglial models, with recent methodological advances including scSNV-seq and ONE-STEP tagging systems that significantly enhance precision genome editing capabilities.

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Michael Boutrosمشاهده پروفایل

استاد

German Cancer Research CenterGermany

Michael Boutros is a Full Professor at Heidelberg University and Head of Division at the German Cancer Research Center (DKFZ). He currently serves as Dean of the Medical Faculty at Heidelberg University (since 2023) and Director of the Marsilius Kolleg (since 2020). He has held leadership roles including Coordinator of the Functional and Structural Genomics Program at DKFZ (2014–2023) and Acting Scientific Director (2015–2016). His academic base is within the Medical Faculty, focusing on molecular oncology and functional genomics. PhD, Witten/Herdecke University (1993–1996) Postdoctoral Research, Harvard Medical School (1999–2003) MPA, John F. Kennedy School of Government, Harvard University (1999–2001) Additional training: Cold Spring Harbor Laboratory, SUNY Stony Brook His research centers on Wnt signaling, functional genomics, and cancer pathways. He leads major research initiatives such as CRC 1324 on Wnt signaling and the ERC Synergy Grant DECODE. His work integrates high-throughput screening, CRISPR, and systems biology to dissect signaling networks in cancer and development. He has pioneered genome-wide RNAi and CRISPR screens to identify novel regulators of Wnt signaling across models. The 15 most recent articles reflect a strong focus on Wnt pathway regulation using functional genomics in both Drosophila and mammalian systems. Themes include high-throughput screening, CRISPR-based validation, cross-species conservation, and therapeutic targeting. Keywords span Cancer Biology, Systems Biology, and Signal Transduction, with subfields like RNAi, ubiquitination, stem cell regulation, and machine learning in image analysis. Michael Boutros has received numerous scientific honors: Elected member, Leopoldina National Academy of Sciences (2022) Elected member, Heidelberg Academy of Sciences (2022) EMBO Member (2013) ERC Advanced Grant (2012) Johann-Georg Zimmermann Research Award (2007) EMBO Young Investigator (2005) Member, 'Die Junge Akademie' (2003) He has been a recipient of the Emmy-Noether Program, McCloy Fellowship, Boehringer Ingelheim PhD Fellowship, Studienstiftung Fellowship, and Fulbright Fellowship. As a mentor and research leader, he has supervised numerous early-career scientists and coordinated large collaborative grants including the FP7 'CancerPathways' project. He currently serves as Speaker of the Research and Strategy Commission at Heidelberg University and Managing Director of the Health and Life Science Alliance Heidelberg Mannheim. He leads the CRC 1324 on Wnt signaling and is Coordinating PI of the ERC Synergy Grant DECODE. He is also Spokesperson of DFG Research Group 1036 and Coordinator of the former FP7 Coordinated Project 'CancerPathways'. His lab employs cutting-edge functional genomics tools to decode signaling networks in cancer and development.

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Nikolaus Rajewskyمشاهده پروفایل

استاد

Max Delbrück Center for Molecular MedicineGermany

Nikolaus Rajewsky is a leading Professor at the Max Delbrück Center for Molecular Medicine (MDC) and Charité – Universitätsmedizin Berlin , where he founded and directs the Berlin Institute for Medical Systems Biology (BIMSB) . His lab integrates experimental (biochemistry, molecular biology) and computational (bioinformatics, physics) approaches to study RNA regulation in gene expression , with applications to developmental biology, regeneration, neurodegenerative diseases, and cancer . Using model systems like C. elegans , planaria, and human brain organoids, his team pioneers cutting-edge methods such as MirDeep , DistMap , and FLAM-seq for RNA analysis. His research focuses on single-cell transcriptomics , spatial RNA sequencing , and circular RNA (circRNA) regulation , revealing novel roles for circRNAs like CDR1as in neuropsychiatric disorders. Recent work includes 3D tumor microenvironment mapping and computational modeling of RNA metabolism in diseases. Scientific Awards : Gottfried Wilhelm Leibniz Prize (2012) EMBO Membership (2010) Honorary PhD, Sapienza University of Rome (2014) Berlin Science Award (2009) His team's recent articles highlight breakthroughs in 3D spatial transcriptomics , circRNA degradation mechanisms , and mitochondrial disease modeling using human brain organoids. The lab actively collaborates with clinical partners across Charité and European institutions, driving the LifeTime initiative for cell-based interceptive medicine.

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Mikhail Gelfandمشاهده پروفایل

استاد

Technical University of MunichGermany

Mikhail Gelfand is a Full Professor and Director of the Center for Molecular and Cellular Biology at Skolkovo Institute of Science and Technology (Skoltech), where he also serves as Vice President for Biomedical Research. His distinguished career spans multiple prestigious institutions including Lomonosov Moscow State University and the Higher School of Economics. His educational background includes: 1985: MSc in mathematics (functional analysis) 1993: PhD in physics-mathematics (biophysics) 1998: DSc in biology (molecular biology) 2007: full professor (bioinformatics) Professor Gelfand's research focuses on molecular evolution, comparative genomics, systems biology, and metagenomics. His work examines eukaryotic processes including alternative splicing, mRNA editing, and chromatin structure, as well as bacterial genome evolution and transcription regulation. His lab combines data on three-dimensional chromatin structure, epigenetic states, and gene expression to obtain an integrated view of genome functioning across diverse organisms from humans to amoebae. One major research direction focuses on the evolution of transcript splicing and editing, while comparative analysis of bacterial genomes yields functional annotations of novel enzymes, transporters, and transcription factors. His recent publications demonstrate a strong focus on RNA editing in cephalopods, bacterial genome analysis, and computational approaches to understanding chromatin structure. The work spans molecular biology, evolutionary biology, and bioinformatics, with particular emphasis on how RNA editing contributes to adaptation and molecular evolution across metazoans. His research shows how edited adenines are more frequently substituted with guanine in evolution than their unedited counterparts, suggesting RNA editing may enhance adaptation. His notable awards include: The President of Russian Federation's Award for Young Doctors of Science (2000) The "Best Scientist of the Russian Academy of Sciences" award (2004) A. A. Baev Prize in Genomics and Genoinformatics (2007) Member of Academia Europaea (2010) As Director of the Center for Molecular and Cellular Biology, Professor Gelfand leads a research group that combines computational and experimental approaches to study genome function and evolution. His lab's work has significant implications for understanding molecular mechanisms of evolution and adaptation across diverse biological systems, from bacteria to complex eukaryotes. His research on metagenomics extends to practical applications in areas including coral disease, aphids, and oil wells.

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Anne Schaeferمشاهده پروفایل

استاد

Max Planck Institute for Biology of AgeingGermany

Anne Schaefer is a Full Professor with Tenure at the Mount Sinai School of Medicine, currently serving as Managing Director at the Max Planck Institute for Biology of Ageing in Cologne, Germany. She co-directs the Center for Glial Biology within the Friedman Brain Institute, focusing on neuroscience and psychiatry. Education: Charité University Berlin (MD/PhD), Johannes Gutenberg University Mainz (undergraduate) Research Interests: Schaefer’s work bridges neuroscience , neuroimmunology , and epigenetics , with a primary focus on microglial biology, neuronal activity regulation, and mechanisms underlying neurodegeneration. Her studies explore how microglia interact with neurons to maintain brain homeostasis and drive plasticity. Scientific Awards: Max Planck Sabbatical Award (2019) Inaugural NINDS Landis Award for Outstanding Mentorship (2018) NIH Director’s New Innovator Award (2012) Kavli Frontiers in Science Fellow (2014) German Research Foundation DFG Research Fellowship (2006–2008) Summa cum laude, Charité University Berlin (2004) Grants & Funding: Schaefer has secured significant third-party funding, including an ERC Synergy Grant (2021–2027) for the project "Micro-'COPS' - Microglia-control of physiological brain states." Labs & Teams: She leads a research team at the Max Planck Institute for Biology of Ageing and collaborates closely with the Center for Glial Biology at Mount Sinai, where she has held leadership roles since 2017.

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Jörg Hackermüllerمشاهده پروفایل

استاد

Helmholtz Centre for Environmental ResearchGermany

Prof. Dr. Jörg Hackermüller is a computational biologist with expertise in Omics data integration Toxicology Environmental risk assessment Non-coding RNA biology . He serves as Head of the Department of Computational Biology and Chemistry at the Helmholtz Centre for Environmental Research (UFZ) since 2024 and holds a Professorship at the Faculty of Mathematics and Computer Science at Leipzig University since 2021. His research focuses on Developing AI methods for chemical toxicity prediction Multi-omics integration for mechanistic toxicology Data standardization in environmental monitoring Non-coding RNAs as biomarkers in disease and toxicity and has produced 15+ recent publications spanning tools like multiGSEA and deepFPlearn+ . He collaborates with teams across UFZ Leipzig University Novartis Fraunhofer Institute and leads projects like InCeTo and SafePol , integrating exposome research with systems biology.

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Kirsten Jungمشاهده پروفایل

استاد

Ludwig Maximilian University of MunichGermany

Bacterial Signal Transduction
Stress Response Mechanisms
Membrane Protein Structure-Function Analysis
+۳ مورد دیگر

Prof. Dr. Kirsten Jung is a faculty member at the Department of Microbiology , Faculty of Biology , Ludwig Maximilian University of Munich . Her research focuses on bacterial signal transduction, stress response mechanisms, and systems biology approaches to understand microbial regulatory networks. Key research areas include stress-dependent gene expression in bacterial populations Structural and functional analysis of membrane-integrated receptors Metabolism-based chemical communication in bacteria Integration of experimental and computational systems biology Recent publications highlight her lab's work on Escherichia coli epitranscriptomic modifications under heat stress, m 5 C rRNA dynamics, and the role of RNA methylation in host-pathogen interactions. Collaborative studies address bacterial acid stress responses and their implications for antibiotic tolerance. Her interdisciplinary work bridges microbiology with ecological studies, as evidenced by research on biodiversity conservation in forest and urban ecosystems. Publications also demonstrate expertise in advanced imaging techniques (e.g., arterial spin labeling for glioma analysis) and bioinformatics approaches. Current advisees include Gloria Gessinger and Tania P. Gonzalez-Terrazas . She can be contacted at jung@lmu.de .

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Michael Veitمشاهده پروفایل

دانشیار

Free University of BerlinGermany

PD Dr. Michael Veit is an Associate Professor (Privatdozent) at the Institute of Virology, School of Veterinary Medicine, Freie Universität Berlin , where he heads the independent Research Group Veit – Cell Biology of Viral Infections . He is a faculty member of the Center for Infection Medicine and participates in the Berlin Equine Virus Lab (BEVL). Education & Training Doctorate (Dr. rer. nat.) in Virology/Biochemistry – exact institution not stated in text. Post-doctoral qualification (Privatdozent) awarded by Freie Universität Berlin. Research Focus Veit’s laboratory investigates the molecular and cellular biology of enveloped RNA viruses , with emphasis on virus–host membrane interactions and post-translational lipid modifications (S-acylation/palmitoylation). His group combines reverse genetics, live-cell imaging, mass spectrometry and structural approaches to dissect how viral glycoproteins are modified, trafficked and assembled into infectious particles. Model pathogens include influenza A, B, C and D viruses, coronaviruses (SARS-CoV-2, MERS-like CoVs, PHEV, PDCoV), arteriviruses (PRRSV, EAV), alphaviruses (Getah, CHIKV-like), and other emerging zoonotic agents. Publication Trends From 2020 to 2025 Veit has published >30 high-impact articles that cluster around four major themes: (i) coronavirus surveillance and zoonotic risk assessment , (ii) mechanistic dissection of protein acylation in influenza and arteriviruses , (iii) structure-function analysis of viral entry receptors (ACE2, LDLR), and (iv) development of reverse-genetic tools and reporter viruses for antiviral screening. Grants & Collaborative Networks Ongoing third-party funded projects coordinated by Veit are not explicitly listed in the text, but the continuous publication output and mention of “Current Collaborations” imply active grant support. He collaborates closely with other FU Berlin groups (Osterrieder, Kaufer, Azab) and international partners on coronavirus and influenza consortia. Laboratory & Teams The Research Group Veit comprises post-docs, PhD students and technicians working in BSL-2 and BSL-3 facilities at the Institute of Virology. Core platforms include confocal & FLIM microscopy, quantitative proteomics, and reverse-genetics suites for segmented RNA viruses.

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Seraphine V. Wegnerمشاهده پروفایل

استاد

University of MünsterGermany

Seraphine V. Wegner is a Full Professor at the Institute of Physiological Chemistry and Pathobiochemistry within the Medical Faculty of the University of Münster. She leads an active research group focused on the spatiotemporal control of cell-material and cell-cell interactions using visible light. Her work bridges synthetic biology, cell biology, and photochemistry to create innovative approaches for tissue engineering and minimal cellular systems. Dr. Wegner's educational background includes a PhD from the University of Chicago (2005-2010) and undergraduate studies at Middle East Technical University in Turkey (2002-2005). Her career path has taken her through prestigious institutions including the Max Planck Institutes in Mainz and Heidelberg, where she established her independent research before joining the University of Münster as a Full Professor in 2019. Her research spans several interconnected areas including light-controlled minimal cellular systems, photoswitchable cell-cell interactions for tissue engineering, light-controlled cell-material interactions, and engineering designer biofilms with light. These research themes share a common thread of using light as a non-invasive tool to precisely control biological processes with high spatial and temporal resolution. Dr. Wegner's publication record shows consistent high-impact output across leading journals in cell biology, synthetic biology, and materials science. Her recent work demonstrates increasing sophistication in multi-color light control systems and applications in both fundamental biological questions and potential therapeutic approaches. ERC Consolidator Grant (2024): LIGHTHOUSE - Light as a signal for nonchemical cell-to-cell communication ERC Starting Grant (2018): ARTIST - Artificial cell-cell interactions for light switchable cell organization and signaling Young Leaders in Science Program, Schering Foundation (2016) MaxSynBio Independent Group Leader, BMBF/MPG (2015) Her research group actively collaborates across disciplines, with projects spanning from fundamental biophysics of cell adhesion to potential medical applications in tissue engineering and bacterial therapeutics. Dr. Wegner has established herself as a leader in the emerging field of optogenetic control of multicellular systems.

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Chris Meierمشاهده پروفایل

استاد

University of HamburgGermany

Prof. Chris Meier is a distinguished Professor of Organic Chemistry at the University of Hamburg, Germany, where he leads the research group AG Meier within the Institute of Organic Chemistry, Department of Chemistry, Faculty of Mathematics, Informatics and Natural Sciences (MIN Faculty). With over two decades of academic leadership, he serves as Co-Speaker of Collaborative Research Center 1648 "Emerging Infections" and has held significant roles including Scientific Director of the Centre for Structural Systems Biology (CSSB) and President of the International Society for Nucleosides, Nucleotides and Nucleic Acids (IS3NA). Dr. Meier's educational background includes a Chemistry degree (Dipl. Chem.) from the University of Marburg/Lahn (1982-1987), followed by his doctorate in Organic Chemistry from the same institution (1987-1989). He completed postdoctoral research at the Pasteur Institute in Paris (1990-1991) and habilitated at Goethe University Frankfurt (1996) before his appointment as C4/W3 Professor at the University of Hamburg in 1999. Professor Meier's research program focuses on nucleoside and nucleotide chemistry, with particular emphasis on pronucleotide development, antisense oligonucleotide chemistry, and stereoselective synthesis of carbocyclic nucleoside analogs. His laboratory investigates molecular mechanisms of chemical carcinogenesis through synthesis of arylamine-modified oligonucleotides and develops innovative organic synthesis methods based on solid support. The group's work bridges fundamental organic chemistry with biomedical applications, particularly in antiviral and anticancer drug development. Recent publications highlight advancements in TriPPP ro -technology for nucleoside triphosphate delivery and metabolic labeling applications. 2018: Antonín Holý Memorial Award from the International Society for Antiviral Research (ISAR) 2007: William Prusoff Award from ISAR 1995: Adolf-Messer Prize for Interdisciplinary Research 1992-1996: Habilitation Scholarship from the German Research Foundation (DFG) 1990-1992: Liebig Postdoctoral Fellowship Professor Meier has successfully mentored numerous doctoral students and postdoctoral researchers, many of whom have gone on to establish independent research careers. His laboratory maintains active collaborations with virology and immunology groups across Europe, particularly with institutions in France (Pasteur Institute, University of Aix-Marseille) and Belgium (KU Leuven). The group has secured substantial funding through multiple Collaborative Research Centers (SFBs) and has developed several patented technologies related to pronucleotide delivery systems. The Meier laboratory operates state-of-the-art organic synthesis facilities within the Institute of Organic Chemistry and maintains close ties with the Centre for Structural Systems Biology (CSSB), where they utilize advanced imaging and structural biology techniques to characterize their compounds. The research group actively participates in the International Society for Antiviral Research and contributes to the development of novel antiviral strategies through both basic research and translational applications.

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Christian Freundمشاهده پروفایل

استاد

Heidelberg UniversityGermany

Christian Freund is Professor of Protein Biochemistry at the Institute for Chemistry & Biochemistry, Freie Universität Berlin, holding this W2 professorship since 2011. He serves as Coordinator of the FU Berlin-UCSF Collaborative Initiative and Founding Member/Vice-chair of the DFG Collaborative Research Centre SFB/TRR 186 on Molecular Switches in Cellular Signal Transmission, leading interdisciplinary research across Berlin and Heidelberg institutions. His academic foundation includes Chemistry studies at Heinrich-Heine-Universität Düsseldorf (1983-1986) and Ludwig-Maximilians-Universität München (1986-1989), followed by a PhD in Structural Biology at the Max-Planck-Institute of Biochemistry (1994) and Habilitation in Biochemistry at Freie Universität Berlin (2005). Freund's research integrates structural biology, biophysics, and immunology to investigate molecular mechanisms of antigen presentation and cellular signaling. His work centers on MHC class II dynamics, protein conformational switches, and nanoscale organization of signaling complexes, employing NMR spectroscopy, quantitative proteomics, and molecular engineering to dissect immune recognition pathways and neuronal signaling mechanisms. Analysis of his 2010-2019 publications reveals consistent focus on MHC-mediated antigen presentation (60% of works), with significant contributions to understanding peptide exchange dynamics and HLA-DM editing functions. Secondary research streams explore synaptic protein networks (25%) and T cell signaling machinery (15%), demonstrating methodological breadth across structural biology, proteomics, and cell biological approaches. His scientific recognition includes: Biofuture award from the German Ministry of Education and Research (1999) Swiss National Funds Post-doctoral Scholarship (1997) Innovationswettbewerb Medizintechnik grant (2009) As research group leader at Leibniz-Institute of Molecular Pharmacology (2000-2011) and current FU Berlin professor, Freund has secured major collaborative funding through DFG SFB/TRR 186 and the UCSF partnership. His mentorship spans postdoctoral fellows at Harvard/Dana-Farber and Leibniz-Institute, with current supervision of graduate students in the Berlin biochemistry program. Freund directs a research group within FU Berlin's Institute for Chemistry & Biochemistry, operating as core component of SFB/TRR 186. His laboratory maintains active collaborations with UCSF's QBI (Nevan Krogan) and Heidelberg-based structural biology teams, utilizing advanced NMR, cryo-EM, and single-molecule imaging facilities across the Berlin-Heidelberg research alliance.

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