جست‌وجوی استاد و پژوهشگر

Bettina Siebersمشاهده پروفایل

استاد

• Archaea
• Central Carbohydrate Metabolism
• Extremozymes
• +۱۳ مورد دیگر

Prof. Dr. Bettina Siebers is a full Professor at the University of Duisburg-Essen, Faculty of Chemistry, where she leads the research group Molecular Enzyme Technology and Biochemistry (MEB). Her work is embedded in the Zentrum für Medizinische Biotechnologie (ZMB) and focuses on hyperthermophilic archaea, central carbohydrate metabolism, and biotechnological applications of extremozymes. She is actively involved in funded research projects, including a major €1.4 million grant from the VolkswagenStiftung for sustainable bio-production. Research Interests: Her research spans archaeal biochemistry, systems biology, metabolic engineering, and enzyme technology. She investigates the unique metabolic pathways in archaea, particularly under extreme conditions, combining classical biochemistry with genomics, transcriptomics, and computational modelling. Her group explores transcription regulation, stress responses, and protein phosphorylation in archaea as simplified models for eukaryotic processes. Publication Trends: Her recent publications emphasize enzyme cascade optimization, extremozyme discovery, metabolic pathway modelling (e.g., Weimberg pathway), and archaeal gene regulation. The interdisciplinary work bridges microbiology, biotechnology, and systems biology, with strong applications in sustainable bioproduction and industrial biocatalysis. Scientific Recognition: Lead Principal Investigator, VolkswagenStiftung 'Biofabrik' Project (€1.4 million) Active publications in high-impact journals including Nature , Nature Communications , FEMS Microbiology Reviews , and Nucleic Acids Research Member of ZMB and contributor to DFG, EU, and NRW-funded research programs Advising and Grants: While specific students are not listed, her group includes postdocs and researchers such as Dr. Christopher Bräsen. She leads major funded projects, including the VolkswagenStiftung initiative to replace microplastics with microbial lipids. Her work is supported by national and international collaborations, particularly with TU Wien. She integrates fundamental research with translational biotechnological applications. Labs and Teams: The MEB group at the University of Duisburg-Essen comprises a dedicated team including a laboratory manager, secretariat, and researchers. The group is part of the ZMB and collaborates within the Faculty of Chemistry and beyond, focusing on extremophile biochemistry and sustainable biotechnology.

Gerhard Wolberمشاهده پروفایل

استاد

• Computational Drug Design
• G-Protein Coupled Receptors (GPCRs)
• Cytochrome P450 Enzymes
• +۳ مورد دیگر

Professor Gerhard Wolber leads the Molecular Drug Design research group at the Institute of Pharmacy , Freie Universitaet Berlin. His work focuses on computational approaches to drug discovery, with expertise in G-protein coupled receptors (GPCRs) , cytochrome P450 enzymes , Toll-like receptors , and viral protease inhibitors . He supervises a team of 13 PhD candidates 3 researchers 2 Master's students engaged in projects ranging from calcium channel blockers to CYP enzyme modulators for cancer therapy. Recent publications highlight his lab's contributions to pan-coronavirus drug discovery, TLR8 antagonism, and calcium channel inhibition. The team employs advanced methodologies including Molecular dynamics simulations Fragment-based de novo design Bayesian neural networks DFT calculations 3D pharmacophore modeling to bridge computational predictions with experimental validation. Notable projects include Virtual screening for TREM2-targeted glioblastoma therapeutics Allosteric communication path analysis via MDPath Immune checkpoint inhibitors for cancer immunotherapy Biased GPCR ligand development demonstrating a multidisciplinary approach to contemporary drug design challenges.

Felix Jonasمشاهده پروفایل

استادیار

• Biochemistry
• Gene Regulation
• Transcription Factors
• +۴ مورد دیگر

Prof. Dr. Felix Jonas is an Assistant Professor of Biochemistry at the School of Science, Constructor University Bremen, Germany. He leads research on the biochemistry of gene regulation , focusing on molecular mechanisms governing transcription factor function and chromatin dynamics in Saccharomyces cerevisiae . His work integrates CRISPR-Cas9, Next-Generation Sequencing, and computational data analysis. Education: B.Sc. in Molecular Life Sciences (University of Luebeck), M.Sc. in Biology: Cell Biology (ETH Zurich), Ph.D. in Bioengineering (Imperial College London) Work Experience: Postdoc/Senior Postdoc at Weizmann Institute of Science (2017-22), Visiting Student at Weizmann Institute (2015-16), International Program Associate at RIKEN (2011) Teaching: General Biochemistry (CH-100-B), Introduction to Bioinformatics (JTMS-10), Current Topics in Life Sciences (CA-BCCB-801), Advanced Biochemistry II - Molecular Genetics (CO-403-A) His research explores transcription factor target search , histone dynamics , and chromatin structure-function relationships . Recent publications highlight discoveries in nucleosome replacement, protein disorder grammar, and histone acetylation impacts on replication. Articles emphasize interdisciplinary approaches to eukaryotic gene regulation and systems biology. Visit his lab’s PhD recruitment page or watch his Fragile Nucleosome Talk for deeper insights into his work.

Mathias Munschauerمشاهده پروفایل

پژوهشگر

• Molecular Virology
• RNA Biology
• Host-Pathogen Interactions
• +۷ مورد دیگر

Mathias Munschauer leads the Department of Molecular Virology at Heidelberg University's Faculty of Medicine, within the Center for Infectious Diseases. His research group focuses on unraveling RNA regulatory mechanisms that govern viral infection outcomes, with emphasis on HCV, HBV, and Dengue virus. His research interests lie at the intersection of RNA biology and virology, particularly in understanding how viral RNA molecules interact with host cell components. The lab employs cutting-edge methodologies including RAP-MS and SHIFTR for RNA interactomics, integrated with functional genomics, single-cell transcriptomics, and AI-driven analysis of high-dimensional data. This systems-level approach enables the identification of host factors and regulatory pathways critical for viral replication and immune evasion. The recent publications highlight a strong trend toward spatially and temporally resolved analysis of RNA-protein interactions across diverse RNA viruses. There is a consistent focus on developing and applying innovative technologies to map host-virus interfaces, with applications in identifying antiviral targets and understanding infection mechanisms. The work spans molecular, cellular, and systems biology, with increasing integration of computational and machine learning approaches. Systems virology RNA-protein interactomics Host-pathogen interactions CRISPR screening Single-cell analysis Antiviral strategies Dr. Munschauer mentors a research team and contributes to the doctoral program in Infectious Diseases. His lab develops and shares novel reagents and methods, fostering collaborative science. While specific grants are not listed, the technological sophistication suggests substantial funding support. The lab operates within a vibrant research environment alongside other virology groups such as AG Bartenschlager and AG Ruggieri. The Munschauer Lab is part of a larger virology and infectious disease research ecosystem at Heidelberg University, collaborating across disciplines to advance understanding of viral pathogenesis. The team actively develops and applies innovative tools for RNA-centric discovery, positioning the group at the forefront of molecular virology.

Maria Roblesمشاهده پروفایل

استاد

• Chronobiology
• Circadian Rhythms
• Sleep Research
• +۹ مورد دیگر

Prof. Dr. Maria Robles is a full Professor and Head of the Systems Chronobiology research group at the Institute of Medical Psychology, Ludwig-Maximilians-Universität München (LMU), Faculty of Medicine. She leads a dynamic research lab focused on circadian rhythms, sleep, and their molecular underpinnings in health and disease, using cutting-edge quantitative proteomics and mass spectrometry as core methodologies. Her research spans multiple domains, including Circadian regulation of metabolism Molecular mechanisms of sleep and synaptic function Circadian clock dysfunction in diseases such as pancreatic cancer Development of novel proteomic methods (e.g., DIA, multi-omics integration) The analysis of her 15 most recent publications reveals a strong trend toward integrating proteomics with systems biology to dissect temporal dynamics in mammalian tissues. Her work frequently explores post-translational modifications, particularly phosphorylation and ubiquitination, in circadian and sleep contexts, with increasing translational focus on cancer biology and therapeutic targeting. She actively mentors PhD students and postdoctoral researchers, contributing to training the next generation of scientists in chronobiology and proteomics. Her lab is affiliated with the Biomedical Center (BMC) at LMU and is equipped with state-of-the-art instrumentation, including Orbitrap and Q-Exactive mass spectrometers, supported by DFG and LMU funding. She collaborates extensively, notably with Dieter Saur (TUM) on pancreatic cancer research.

Jane A. McKeatingمشاهده پروفایل

استاد

• Virology
• Hepatology
• Molecular Biology
• +۳ مورد دیگر

Jane A. McKeating is a Professor of Molecular Virology at the University of Oxford's Nuffield Department of Medicine. She holds the Hans Fischer Senior Fellowship at the Technical University of Munich's Institute for Advanced Study (TUM-IAS) since 2015. Her research focuses on viral infections, particularly hepatitis B (HBV) and C (HCV), exploring how hypoxia and circadian rhythms regulate viral replication and pathogenesis. She has held roles at institutions including the University of Birmingham (2005–2017) and Rockefeller University (2000–2005). Education: BSc in Biological Sciences, University of Warwick (1982) PhD in Virology, Royal Free Hospital School of Medicine, University College London (1987) Research Interests: Her work investigates how low oxygen (hypoxia) and circadian signaling pathways influence viral replication and tropism, particularly in liver and immune cells. Recent studies include SARS-CoV-2 regulation by hypoxia-inducible factors (HIFs) and circadian clock components like BMAL1. She also examines therapies targeting these pathways to combat viral infections. Publications: Her recent work spans hepatitis virus biology, antiviral screening tools, and circadian regulation of viral infections. Key themes include viral entry mechanisms, immune evasion, and drug development. Awards: 2015 Founders Award, University of Birmingham 2006 Royal Society Wolfson Merit Award 1995 Fleming Award, Society of General Microbiology Lab & Collaborations: Her research group at Oxford focuses on viral-host interactions, with collaborations on spatial transcriptomics of HBV/HDV/HIV co-infections and antiviral drug screening platforms.

Henning Urlaubمشاهده پروفایل

استاد

• Mass Spectrometry
• Proteomics
• Protein Interactions
• +۷ مورد دیگر

Prof. Henning Urlaub is a Professor at the Faculty of Medicine at Georg August University Göttingen and Group Leader of the Bioanalytical Mass Spectrometry Group at the Max Planck Institute for Multidisciplinary Sciences (formerly Max Planck Institute for Biophysical Chemistry). His roles include leading a research group focusing on proteomics and clinical biochemistry at the University Medical Center Göttingen (UMG). He holds dual affiliations in both academic and clinical research sectors. He earned his Ph.D. in biochemistry from the Free University of Berlin (1993–1996) and conducted postdoctoral research at institutions including the Max Delbrück Center for Molecular Medicine (Berlin) and the Philipps University of Marburg. His career includes leadership roles since 2010 in both the Max Planck Institute and UMG. Research Interests : Dr. Urlaub’s work centers on modern mass spectrometry applications for analyzing proteins, post-translational modifications, and protein interactions. Key projects include: Quantitative analysis of synaptic proteins under stimulation Protein cross-linking studies in B cells and other systems Method development for protein-RNA/DNA interactions Structural elucidation of large complexes via CX-MS and cryo-EM His group operates as a core proteomics facility for the Max Planck Institute and collaborates with external institutions like the University Hospital Frankfurt. They also maintain a clinical proteomics branch at the UMG’s Institute for Clinical Chemistry. Collaborations & Infrastructure : The group provides proteomics services to researchers across disciplines, emphasizing translational and clinical applications. Their instrumentation includes advanced mass spectrometry platforms (e.g., ESI, MALDI) for high-throughput proteomic analysis.

• Molecular Biology
• CRISPR-Cas Systems
• Microbial Genetics
• +۳ مورد دیگر

Professor Lennart Randau is a leading researcher in the field of Genetics at Philipps University of Marburg, affiliated with the Faculty of Biology. His work is conducted in conjunction with the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, where he investigates molecular mechanisms underlying CRISPR-Cas systems and related biotechnological applications. Research focus on CRISPR-Cas evolution and inhibition mechanisms Investigates structural and functional diversity of prokaryotic defense systems Active in developing genome engineering tools from microbial systems His recent publications highlight CRISPR-Cas transitions from natural immunity to synthetic biology applications, with particular emphasis on anti-CRISPR proteins and transposon-associated gene integration mechanisms. Professor Randau's laboratory employs interdisciplinary approaches combining molecular biology, biochemistry, structural biology, and genomics to unravel the complexities of microbial genetic defense systems and their potential applications in biotechnology.

• Molecular Biology
• Gene Expression
• RNA Biology
• +۳ مورد دیگر

Markus Bohnsack is a Professor at the University Medical Center Göttingen, affiliated with the Department of Molecular Biology. His research focuses on the mechanisms and coordination of gene expression processes, particularly the biogenesis and dynamics of RNA-protein complexes (RNPs), RNA helicases, and RNA modifications. Research Areas: Gene expression regulation, RNP dynamics, RNA helicases, RNA modifications in gene expression, cross-regulation of cellular processes. Methods: Molecular biology, biochemistry, cell biology, transcriptome/proteome-wide approaches (CRAC, mass spectrom2etry), interdisciplinary collaborations. His work explores how RNA helicases structurally remodel RNAs/RNPs and the roles of RNA modifications in disease pathogenesis.

Stephanie Panierمشاهده پروفایل

استاد پژوهشی

• Genome Stability
• DNA Damage Response
• Aging Research
• +۴ مورد دیگر

Dr. Stephanie Panier serves as a Max Planck Research Group Leader at the Max Planck Institute for Biology of Ageing in Cologne, Germany, and as a Principal Investigator at the Institute for Genome Stability in Aging and Disease within the Medical Faculty of the University of Cologne. Her research program investigates the fundamental mechanisms by which cells maintain genome stability through sophisticated DNA damage response pathways. Her academic journey includes: PhD in Molecular Genetics from the University of Toronto (2008-2013) under Prof. Daniel Durocher Postdoctoral training at the Francis Crick Institute in London (2013-2019) with Prof. Simon Boulton Undergraduate studies in Biology at Ruprecht-Karls-Universität Heidelberg, Germany (2001-2006) Dr. Panier's laboratory focuses on two central questions in genome stability research: how DNA damage response pathways interact with telomere maintenance mechanisms, and how RNAs and RNA-binding proteins organize chromatin-based responses to DNA lesions. Her team employs cutting-edge cell biological and omics approaches to identify and characterize RNA-binding proteins at DNA damage sites, mapping their chromatin dynamics and interactions following genotoxic stress. This research has significant implications for understanding aging-associated diseases driven by genomic instability, including cancer and neurodegeneration. Analysis of her publication record reveals consistent contributions to understanding DNA repair mechanisms, with recent work expanding into cancer biology, telomere maintenance in alternative lengthening pathways, and the emerging role of RNA metabolism in genome stability. Her scientific achievements have been recognized through: Vivash Award for best PhD thesis (2013) FEBS Excellence Award (2023) EMBO Long-Term Fellowship (2013-2014) Vanier Canada Graduate Scholarship (2010-2013) Boehringer Ingelheim Fonds PhD Fellowship (2008-2010) EIRR21st Fellowship (2023) Dr. Panier actively contributes to the scientific community through leadership roles including Vice Coordinator of the DFG Research Unit FOR5504 (2023-2026), membership on the advisory board of the German Society for Research on DNA Repair since 2022, and representation on the Biology and Medicine Section of the Max Planck Society's scientific council since 2022. She also serves as a Principal Investigator in the Cologne Excellence Cluster 'Cellular Stress Responses in Aging-Associated Diseases' (CECAD). Her laboratory comprises postdoctoral researchers and PhD students working collaboratively to advance our understanding of genome stability mechanisms in aging, with current projects focusing on RNA-binding proteins in DNA damage response and telomere maintenance pathways.

Lydia Herzelمشاهده پروفایل

استادیار

• RNA Biology
• Molecular Biology
• Biochemistry
• +۳ مورد دیگر

Lydia Herzel is an Assistant Professor in the Department of Biochemistry at the Freie Universität Berlin, affiliated with the Department of Biology, Chemistry, Pharmacy. Her research focuses on RNA dynamics, particularly mRNA regulation in fungi and bacteria, combining biochemistry, bioinformatics, and molecular biology. She leads the Herzel Group, which explores co-transcriptional RNA regulation and its impact on gene expression outcomes. The group employs advanced RNA sequencing and biochemical techniques to study transcriptome diversity and regulatory mechanisms. Her work spans topics such as RNA splicing, mRNA decay, and the interplay between transcription and post-transcriptional processes. Key areas include understanding how regulatory mechanisms influence fungal pathogenesis (e.g., Candida albicans) and bacterial gene expression. She collaborates on projects involving synthetic biology, codon usage, and functional genomics. Recent studies highlight her group’s contributions to understanding spliceosome function in morphogenesis and the development of novel clathrin inhibitors. She actively mentors students, including Javier Callís Creus, a former bachelor’s thesis student. The lab seeks motivated researchers interested in integrating biochemistry, microbiology, and bioinformatics. Her research has been published in high-impact journals such as Nature Reviews Molecular Cell Biology , Nucleic Acids Research , and mBio . Her work bridges fundamental biology with biomedical applications, aiming to translate regulatory insights into therapeutic strategies.

• Electric Vehicles
• Fuzzy Logic
• Blockchain
• +۵ مورد دیگر

Shahid Hussain is an Associate Professor at King Abdullah University of Science and Technology (KAUST) in the Computer, Electrical and Mathematical Sciences and Engineering Division. His research spans multiple domains including electric vehicle infrastructure, blockchain technology, and intelligent systems for IoT applications, with a focus on practical implementations of computational intelligence techniques. Dr. Hussain's research interests include: Electric Vehicles and Smart Grid Integration Fuzzy Logic and Intelligent Decision Systems Blockchain Applications for Security and Privacy Machine Learning for IoT and Healthcare Applications Energy Management Systems Smart City Infrastructure Development His recent publications demonstrate a strong focus on applying hybrid computational approaches to solve complex engineering problems, particularly in transportation systems and healthcare applications. Dr. Hussain has published extensively in IEEE journals, with particular emphasis on innovative approaches to electric vehicle charging infrastructure, secure IoT systems, and blockchain-enabled solutions for real-world challenges. Dr. Hussain maintains active collaborations with researchers globally, particularly with Reyazur Rashid Irshad, Young-Chon Kim, and Subhasis Thakur. His work bridges theoretical advancements with practical implementations, as evidenced by his research on fuzzy integer linear programming for EV charging stations and blockchain-enabled security frameworks for medical IoT systems.

Dagmar Wirthمشاهده پروفایل

استاد پژوهشی

• Virology
• Immunology
• Gene Regulation
• +۴ مورد دیگر

Prof. Dagmar Wirth is a Research Professor and Head of the 'Model Systems for Infection and Immunity' research group at the Helmholtz Centre for Infection Research (HZI). Her work focuses on gene regulation, viral infections, and immune evasion mechanisms, with a particular emphasis on developing genetically modified mouse models for studying infectious diseases and immune responses. She leads the Service Unit 'Transgenic Mice' (TGSM), providing expertise in transgenic model systems to the HZI community. Affiliations: HZI (since 2004), previously at the Medical University of Hannover. Education: Chemistry studies in Braunschweig, PhD at GBF (now HZI), postdoctoral research on viral recombination and gene therapy. Her research interests include viral pathogenesis (e.g., Kaposi's sarcoma-associated herpesvirus), engineered cell-based therapies, and controlled drug delivery systems using macrophages and nanoparticles. She has pioneered models for hepatitis C virus infection in mice and developed biosensors to detect bacterial infections. Publications: Over 150 peer-reviewed articles, focusing on virology, immunology, and genetic engineering. Recent work includes studies on antibacterial coatings for implants, ultrasound-activated drug release, and the role of senescence in herpesvirus infection. Labs/Teams: Leads the MSYS group and collaborates with teams in virology, immunology, and biomedical engineering. Active in developing 3D in vitro models for studying infection and immune responses.

Dario Leisterمشاهده پروفایل

استاد

• Regulation of Photosynthesis
• Retrograde Signaltransduction
• Bio-Hybridsystems for Photovoltaik and Photokatalyse
• +۳ مورد دیگر

Prof. Dr. Dario Leister is a Chair of Plant Molecular Biology/Botany at the Ludwig-Maximilians-University Munich (LMU) , where he leads research on photosynthesis regulation, retrograde signaling, and bio-hybrid systems for photovoltaics. His lab focuses on chloroplast functions, stress responses, and synthetic biology to enhance photosynthetic efficiency. Education: Diploma in Biochemistry (University of Tübingen, 1993); PhD in Genetics (Max-Planck-Institute, 1995); Habilitation in Genetics (University of Tübingen, 2003). Recent research trends include optimizing photosynthesis under fluctuating light, engineering cyanobacterial systems for stress tolerance, and exploring chloroplast-mitochondria interactions. His work spans molecular genetics, RNA biology, and nanotechnology-based applications. Scientific Awards: Top Author Award (ASPB, 2015); Karl-Lohmann-Prize (2003); Heisenberg Scholarship (DFG, 2003-2005); EMBO Long-Term Fellowship (1997-1998). He chairs the Transregio 175 consortium ( The Green Hub ) and serves on the Faculty Board of LMU's Faculty of Biology. His lab investigates chloroplast development, redox signaling, and adaptive evolution in plants.

• Molecular Biology
• Microbiology
• Biochemistry
• +۴ مورد دیگر

Stefan Irniger serves as a faculty member at a German-speaking academic institution, where he has supervised numerous doctoral candidates between 2004 and 2014. His academic position as a Privatdozent (PD) indicates he has completed the habilitation process, the highest academic qualification in the German system. Dr. Irniger's research spans multiple areas of molecular and cellular biology, with particular emphasis on: Microbial pathogenesis and host-pathogen interactions Fungal and yeast molecular genetics Protein regulation and post-translational modifications Enzyme structure and function Cellular metabolism and signaling pathways His doctoral students have published work examining diverse biological systems including Toxoplasma gondii, Saccharomyces cerevisiae, Aspergillus nidulans, and various plant-pathogen interactions. The publications demonstrate a consistent focus on molecular mechanisms underlying cellular processes, with particular attention to protein regulation, metabolic pathways, and host-microbe interactions. His students' work appears across multiple subdisciplines including parasitology, fungal genetics, enzymology, and membrane biology. Dr. Irniger has guided 18 doctoral students to completion, with dissertation topics spanning from 2004-2014. His students have investigated fundamental biological questions with implications for infectious disease, agricultural pathology, and basic cellular mechanisms. While specific awards are not documented in the available records, the breadth and quality of supervised research indicates significant scholarly contribution to his fields of expertise.