جستجوی استاد راهنمای دانشگاهی

• Microbiology
• Immunology
• Bacterial Vaccines
• +۵ مورد دیگر

James B. Kaper is a Professor and Chair of the Department of Microbiology & Immunology at the University of Maryland School of Medicine. He serves as Vice Dean for Academic Affairs and previously held leadership roles as Senior Associate Dean (2014–2019) and Chair (2007–present). His research focuses on the molecular pathogenesis of diarrheagenic Escherichia coli and Vibrio cholerae , including vaccine development and bacterial-host interactions. Education: BS (1973) and PhD (1979) in Microbiology from University of Maryland; Postdoc in Molecular Pathogenesis at University of Washington (1979–1981) Dr. Kaper’s work has led to the creation of live attenuated cholera vaccines, including CVD 103-HgR, the first licensed recombinant bacterial vaccine. His lab investigates bacterial genetics, intestinal colonization, and immune system activation, particularly TLR5 response to V. cholerae flagellin. He has authored 303 peer-reviewed articles and 68 book chapters. His research has been funded continuously by NIAID since 1982. Key publications include foundational work on V. cholerae vaccines (1984), genomic structure (1998), and quorum sensing in EHEC/EPEC (1999). His lab’s recent studies focus on phosphotyrosine proteomics (2013) and pathogenicity island regulation (2007). Scientific awards: Fellow, American Academy of Microbiology (1994); NIH Merit Award (2004); ASM DC White Award (2019) Editorial roles: Editor-in-Chief, EcoSal (2006–present); Associate Editor, International Journal of Medical Microbiology (2000–present) As an academic leader, Dr. Kaper has mentored over 60 graduate students and postdoctoral fellows. He holds multiple patents for cholera vaccines and E. coli diagnostics, including U.S. Patents 4,935,364; 5,399,494; and 6,204,004. His lab at UMSOM combines basic science with translational applications for enteric disease prevention.

• Evolutionary Biology
• Marine Biology
• Taxonomy
• +۵ مورد دیگر

Mikael Thollesson is a Senior Lecturer at Uppsala University, affiliated with the Department of Organismal Biology; Systematic Biology and Klubban’s Biological Station. His research focuses on evolutionary biology, phylogenetics, taxonomy, and molecular biology, particularly in marine and freshwater sponges (Porifera), bacterial pathogens, and computational methods in evolutionary analysis. Evolutionary Biology Marine Biology Taxonomy His recent publications highlight trends in sponge biodiversity, phylogeography, bacterial horizontal gene transfer, and mitochondrial gene evolution. Key articles include studies on Swedish demosponge faunas, Silene sect. Arenosae systematics, and computational tools like SPRIT for detecting gene transfers. No explicit awards or grants are mentioned.

• Pharmacology
• Traditional Chinese Medicine
• Cancer Therapy
• +۷ مورد دیگر

Wing Lam is an Associate Research Scientist in the Department of Pharmacology at the Yale School of Medicine. He holds a BSc in Molecular Biology and a PhD in Biochemical Pharmacology from City University of Hong Kong, followed by postdoctoral training at Yale. His research focuses on developing traditional Chinese medicine (TCM) formulations as adjuvants for cancer therapy, notably YIV-906, which enhances chemotherapy efficacy and mitigates intestinal toxicity. Lam also pioneered the STAR database for herbal drug discovery and the Mechanism-Based Quality Control (MBQC) platform for botanical drug standardization. Education: BSc (Hons) Molecular Biology, City University of Hong Kong, 1995 PhD Biochemical Pharmacology, City University of Hong Kong, 1999 Postdoc, Pharmacology, Yale University, 1999-2002 His research interests span cancer pharmacology, TCM modernization, and mitochondrial toxicity mechanisms. Key projects include YIV-906’s role in enhancing anti-PD1 and CAR T-cell therapies, developing L-nucleoside analogs like troxacitabine, and investigating tylophorine analogs’ antitumor effects. Lam has co-chaired sessions at multiple Consortium for Globalization of Chinese Medicine (CGCM) meetings and contributed to patents on herbal drug formulations and quality control methods. Recent work explores YIV-906’s potential for inflammatory bowel disease (IBD) and phase II clinical trials for colon and liver cancers. Lam’s publications highlight synergistic drug interactions, mitochondrial DNA depletion mechanisms, and TCM’s evidence-based application in chronic diseases. His grants include studies on PHY906 as an adjuvant in rectal cancer therapy and collaborations with Yiviva, Inc. He maintains active roles in editorial boards, including a special issue on herbal drug quality control in Frontiers in Pharmacology . Lam’s lab is embedded within Dr. Yung-Chi Cheng’s group, focusing on translational pharmacology and botanical drug innovation.

Kelly Arnoldمشاهده پروفایل

دانشیار

• Biomedical Computation and Modeling
• Drug Delivery and Therapeutics
• Systems Immunology
• +۵ مورد دیگر

Kelly Arnold is an Associate Professor in the Department of Biomedical Engineering at the University of Michigan. Her research integrates systems engineering principles with immunology to investigate variability in immune responses across infection, vaccination, and injury, with a focus on computational modeling and clinical translation. Research Focus Systems-level immune response modeling Vaccination and antibody functionality Vaginal microbiome-host interactions Chronic lung disease progression Computational serology and proteomics Recent Work Her 2025 studies examine SARS-CoV-2 vaccination responses in cancer patients and computational frameworks for vaginal probiotics. Earlier works (2024-2007) span COPD progression, lupus fibrosis, HIV susceptibility, and tissue engineering for fertility preservation. Methodologies include proteomic profiling, network modeling, and microfluidic systems.

Patricia Championمشاهده پروفایل

استاد

• Molecular Genetics
• Mycobacterial Pathogenesis
• Bacterial Genetics
• +۷ مورد دیگر

Patricia Champion is a Professor in the Department of Biological Sciences at the University of Notre Dame, where she holds the title of Notre Dame Collegiate Professor. Her research is centered on the molecular mechanisms of mycobacterial pathogenesis, with a focus on protein transport and virulence. She is affiliated with the Eck Institute for Global Health and the Center for Rare and Neglected Diseases. PhD in Molecular Biology, Princeton University (2003) B.S. in Biological Sciences, Carnegie Mellon University (1998) Her research interests lie in understanding how pathogenic mycobacteria, including Mycobacterium tuberculosis and M. marinum , cause disease through targeted protein secretion, particularly via the Type VII (ESX-1) secretion system. She investigates how secreted proteins function as effectors and regulate gene expression, and how post-translational modifications like acetylation influence virulence. Her lab employs an interdisciplinary approach combining genetics, molecular biology, proteomics, and transcriptomics. The recent publications highlight a strong focus on ESX-1-mediated secretion, identification of novel substrates, regulatory mechanisms (e.g., WhiB6, EspM), and post-translational modifications. The work spans fundamental bacterial physiology to host-pathogen interactions, contributing to the broader goal of identifying targets for anti-virulence therapeutics against tuberculosis. Her scientific recognition includes being named a Notre Dame Collegiate Professor, a distinguished honor reflecting her scholarly excellence. Dr. Champion leads an active research laboratory committed to fostering an inclusive and respectful environment, emphasizing core values such as integrity, teamwork, and excellence. Her lab's work is supported by ongoing research grants, though specific funding sources are not detailed in the text. The Champion Lab operates within the Department of Biological Sciences and collaborates with key institutes at Notre Dame focused on global and neglected diseases.

Knut Drescherمشاهده پروفایل

دانشیار

• Bacterial Biofilms
• Microbial Multicellularity
• Biophysics
• +۵ مورد دیگر

Prof. Knut Drescher is an Associate Professor at the Biozentrum, University of Basel , leading a research group focused on bacterial biofilms , swarming , and microbial multicellularity . Previously, he served as a Professor of Biophysics and Max Planck Research Group Leader at Philipps-Universität Marburg (2015-2021) and conducted postdoctoral research at Princeton University. Research Interests: Physical and biological mechanisms of biofilm formation Cell-cell interactions in microbial communities Antibiotic resistance in biofilms Hydrodynamics of bacterial swarms Evolution of cooperation in multispecies biofilms Development of bioimaging software (BiofilmQ, BacStalk) Scientific Awards: 2023: SNSF Consolidator Grant 2019: Heinz Maier-Leibnitz Prize (DFG), VAAM Research Prize, IUPAP Young Scientist Prize 2016: ERC Starting Grant Advising & Grants: Advises PhD and Master's students in microbiology, biophysics, and bioinformatics Secured major grants from ERC , HFSP , and DFG

Urs Jenalمشاهده پروفایل

استاد

• Bacterial Signal Transduction
• Microbiology
• Antibiotic Resistance
• +۵ مورد دیگر

Professor Urs Jenal is a Full Professor at the Biozentrum of the University of Basel, Switzerland, where he has led research on bacterial signal transduction since 2008. His laboratory investigates the molecular mechanisms of bacterial persistence and antibiotic resistance, with particular focus on pathogens causing chronic infections in humans. Previously, he served as Associate Professor (2002-2008) and Assistant Professor (1996-2002) at the same institution, and completed postdoctoral training at Stanford University and ETH Zurich. Education 2000: Habilitation and VENIA DOCENDI in Microbiology, University of Basel 1987-1991: PhD in Molecular Microbiology, ETH Zurich (supervisor: Prof. T. Leisinger) 1982-1986: Studies of Experimental Biology, ETH Zurich 1977-1981: Gymnasium with Matura Type C, Chur Research Focus Prof. Jenal's research centers on understanding how bacterial pathogens persist in the human body despite antibiotic treatments. His laboratory investigates cyclic nucleotides, particularly c-di-GMP, as signaling molecules that control bacterial biofilm formation, virulence, and antibiotic tolerance. His team studies pathogenic Escherichia coli causing recurrent urinary tract infections and Pseudomonas aeruginosa causing long-term lung infections in cystic fibrosis patients. Recent work has revealed how "sleeping" bacteria survive antibiotic treatments and how pathogens breach respiratory epithelia through goblet cell invasion. Scientific Recognition 2014: Elected member of the European Academy of Microbiology (EAM) 2013: ERC Advanced Investigator Award 2012: Elected member of the European Molecular Biology Organization (EMBO) 2011: Elected member of the American Academy of Microbiology (AAM) Mentorship and Collaborations Prof. Jenal has mentored numerous PhD students and postdocs, many receiving awards for their research. His laboratory is part of the NCCR AntiResist initiative focused on developing novel approaches against antibiotic resistance. He collaborates extensively with clinical researchers and has developed innovative models, including human mini-lungs, to investigate pathogen-host interactions. His recent publications demonstrate how understanding bacterial persistence mechanisms can lead to new therapeutic strategies against chronic infections.

Jered Haunمشاهده پروفایل

دانشیار

• Biomedical Engineering
• Molecular Medicine
• Nanotechnology
• +۴ مورد دیگر

Jered Haun is an Associate Professor at the Samueli School of Engineering , University of California, Irvine , with joint appointments in Biomedical Engineering , Chemical and Biomolecular Engineering , and Materials Science and Engineering . Based in 3107 Natural Sciences II , his research focuses on developing nanoengineering and molecular medicine technologies to improve disease diagnosis and treatment. Email: jered.haun@uci.edu Phone: (949) 824-1243 Research Interests include: Nanomaterial Probes for molecular profiling and disease detection Microfabricated Platforms for cell analysis and tissue processing Targeted Delivery Carriers that interact with unique disease molecules Technologies employed in his lab encompass: Fluorescence imaging and MRI enhancements Bioorthogonal chemistry and nanosensor development Micro-NMR for tumor analysis Quantum dot-based detection systems Awards include: NIH National Cancer Institute's Innovative Molecular Analysis Technologies Funding The Haun Laboratory actively recruits graduate and undergraduate students for projects related to nanoengineering, molecular medicine, and microfluidic device development.

• Stem Cell Biology
• Genetic Engineering
• Epigenetics
• +۵ مورد دیگر

Konstantinos Anastassiadis is a Professor at the Center for Molecular and Cellular Bioengineering (CMCB) of Dresden University of Technology , leading the Stem Cell Engineering group at the Biotechnology Center (BIOTEC) . His research focuses on unraveling molecular pathways regulating stem cell self-renewal and lineage commitment, with a strong emphasis on genetic engineering tool development and epigenetic mechanisms during cellular reprogramming. The lab utilizes mouse and human embryonic stem cells, neural stem cells, mesenchymal stromal cells, and induced pluripotent stem cells (iPSCs) in their investigations. Core Research Areas: Molecular regulation of stem cell fate Epigenetic mechanisms (e.g., UTX/UTY histone demethylases) Genetic engineering tool development (Flp, Dre, Vika recombinases, CRISPR protocols) Conditional immortalization systems for rare cell expansion Publications highlight his contributions to understanding: Role of histone methyltransferases (MLL1, MLL2, Setd1b) in hematopoiesis and cancer Epigenetic regulation during mouse development and spermatogenesis Genetic tools for protein tagging, transposon-mediated BAC transgenesis Interactions between stem cells and niche microenvironments Transcriptional and mechanical markers during reprogramming Collaborations span immunology , developmental biology , and bioinformatics . The lab actively participates in teaching activities at CMCB and maintains a focus on translational applications of stem cell research.

Amit R. Reddiمشاهده پروفایل

استاد

• Biochemistry
• Metalloproteins in biological regulation and disease
• Heme trafficking and signaling
• +۴ مورد دیگر

Amit R. Reddi is a Professor at the Department of Chemistry, Georgia Institute of Technology. His research focuses on metalloproteins, particularly the mechanisms of heme trafficking and redox signaling in relation to cancer, neurodegenerative disorders, and infectious diseases. He has received numerous awards for both research and teaching excellence. Education : B.A. from Carleton College (2003) Ph.D. from Columbia University (2008) NIH Postdoctoral Fellowship at Johns Hopkins University (2013) Research Interests : The Reddi laboratory investigates cellular mechanisms of metalloprotein activation and inter-biomolecular communication in metabolic and signaling pathways critical to human health. Key projects explore heme trafficking pathways and the role of Cu/Zn Superoxide Dismutase (SOD1) in redox signaling, with implications for cancer, neurodegenerative diseases, and microbial pathogenesis. Scientific Awards : Vasser Woolley Faculty Fellowship (2021) Student Recognition of Excellence in Teaching Class of 1934 Award (2021) CTL/BP Junior Faculty Excellence in Teaching Award (2019) Bergmann Memorial Award (2018) Blanchard Professorship (2016) NSF CAREER Award (2015) NIH NRSA Post-doctoral Fellowship (2008-2011) Grants & Fellowships : NSF CAREER Award (2015) Sigma Xi Grants-In-Aid-of-Research (2003) NIH Cancer Research Training Award Fellowship (1999-2001)

C. Perry Chouمشاهده پروفایل

استاد

• biochemical engineering
• bioprocessing
• biomanufacturing
• +۷ مورد دیگر

C. Perry Chou is a full professor in the Chemical Engineering Department at the University of Waterloo, with a cross-appointment in Biology. He holds a BSc and MSc from National Taiwan University and a PhD from Rice University, all in Chemical Engineering. His research focuses on integrating biochemical, genetic, and metabolic engineering strategies to enhance biomanufacturing using microbial cell factories. Key areas include recombinant protein production, microbial biotechnology, and biofuel development. Education: PhD in Chemical Engineering, Rice University (1995) MSc in Chemical Engineering, National Taiwan University (1987) BSc in Chemical Engineering, National Taiwan University (1984) Research Interests: Dr. Chou’s work spans biochemical engineering, bioprocessing, and metabolic engineering. He develops strategies for microbial strain construction, fermentation optimization, and bioproduct purification. His research bridges fundamental biological sciences with applied engineering to advance biomanufacturing. Publications: His 90+ peer-reviewed articles highlight contributions to strain engineering, CRISPR-Cas9 tools, and microbial production of chemicals like 5-aminolevulinic acid and propionate. Recent trends emphasize nanomaterial applications (e.g., graphene oxide) and sustainable biofuel pathways. Awards: Canada Research Chair (Canada) 1000-talent Award (China) Advising & Grants: Dr. Chou actively mentors graduate students and contributes to editorial roles at journals like Biotechnology Advances and Scientific Reports . He teaches courses such as CHE 161 (Engineering Biology) and CHE 562 (Advanced Bioprocess Engineering). Labs/Teams: Collaborates with interdisciplinary teams to advance bioprocess development, though specific lab names are not explicitly mentioned in the text.

• Nutritional Systems Biology
• Food Science
• Bioactive Compounds
• +۳ مورد دیگر

Prof. Veronika Somoza is a leading academic in Nutritional Systems Biology, currently affiliated with the University of Vienna and Technical University of Munich (TUM). She holds a professorship in Molecular Food Science and has led key research groups such as the Institute of Physiological Chemistry and the Christian Doppler Laboratory for Bioactive Aromatics. Her career includes roles at institutions like the German Research Institute for Food Chemistry (Garching) and the University of Wisconsin-Madison. Education: Diplom (Justus Liebig University Giessen, 1991), PhD (University of Vienna, 1995), Habilitation (Kiel University, 2002) Research Focus: Bioactive food compounds, flavor chemistry, taste receptor signaling, and gastrointestinal physiology Her work bridges food science and human health, particularly in understanding how food ingredients influence digestion, inflammation, and disease. Notable contributions include discoveries on bitter peptide effects on gastric acid secretion and flavor perception modulation. Awards: FEMA Excellence in Flavor Science (2016), ACS AGFD Fellow (2020), Hans Adolf Krebs Prize (2004) Prof. Somoza has pioneered methodologies in atomic force microscopy for foodborne virus detection and developed bitterness-masking compounds for pharmaceuticals. Her interdisciplinary approach integrates nanobiophysics with nutrition to advance functional food design and clinical applications.

Isabella Guidoمشاهده پروفایل

مدرس ارشد

• Synthetic Biology
• Active Bioinspired Systems
• Active Matter
• +۳ مورد دیگر

Isabella Guido is a Senior Lecturer in Experimental Soft Matter Physics at the University of Surrey's School of Mathematics and Physics. She holds a PhD from TU Berlin (2010) and has conducted postdoctoral research at Peking University and the Max Planck Institute for Dynamics and Self-Organization. Her research focuses on synthetic biology, active bioinspired systems, and microtubule-motor protein dynamics. Guido's work bridges active matter physics and synthetic biology, aiming to develop minimal systems mimicking natural cellular structures. Key projects include synthetic beating structures resembling cilia, 3D active nematics, and investigations into cellular symmetry breaking via biomimetic systems. Her education includes a PhD on dielectrophoretic effects in mammalian cells, followed by postdoctoral studies on cell mechanics, microfluidics, and electroporation. Guido's interdisciplinary approach combines experimental biophysics with synthetic biology to uncover principles governing living matter. She leads the Synthetic Active Systems group and collaborates internationally on projects such as light-powered artificial cells and motor-driven microtubule networks. Her work addresses sustainable development goals through bio-inspired material design and active matter applications. Publications highlight contributions to electrotaxis mechanisms, live-cell imaging techniques (e.g., MIET), and microtubule network dynamics under depletion forces. Guido's research has advanced understanding of ciliary beating patterns, synthetic axoneme models, and biopolymer self-organization under mechanical stress.

Caetano Reis e Sousaمشاهده پروفایل

استاد

• Immunology
• Infectious Disease
• Cancer Immunotherapy
• +۳ مورد دیگر

Caetano Reis e Sousa is a Professor of Immunology at Imperial College London and Senior Group Leader/Assistant Research Director at the Francis Crick Institute. He leads the Immunobiology Laboratory, focusing on dendritic cell biology, immune responses to pathogens, and cancer immunotherapy. His research explores how dendritic cells detect pathogens and dying cells, triggering adaptive immunity. Key roles include investigating cross-presentation mechanisms, C-type lectin receptors (e.g., DNGR-1), and vaccine development strategies. Education: BSc (Hons) Biology from Imperial College London (1989), DPhil in Immunology from University of Oxford (1992). Postdoctoral training at NIH under Ron Germain. Career milestones include founding the Immunobiology Lab at CRUK London Research Institute (1998–2015) before joining the Crick. Awards & Recognition: Highly Cited Researcher (Thomson Reuters), BD Biosciences Prize (2002), Liliane Bettencourt Award (2008), Louis-Jeantet Prize (2017), Fellowships at Royal Society (2019), Academy of Medical Sciences (2006), and EMBO (2006). Named Officer of the Order of Sant'Iago da Espada (Portugal, 2009). Research Themes: Dendritic cell activation pathways, cross-presentation of tumor antigens, microbiome-cancer immunity links, and immune evasion mechanisms. Collaborations involve institutions like UCL, King's College London, and global health networks. Labs/Teams: Head of Immunobiology Lab at Crick, with expertise in immunology, cell biology, and virology. Facilities include Flow Cytometry, Genomics, and Light Microscopy cores. Active in pandemic response (e.g., SARS-CoV-2 testing initiatives).

Thomas Maguireمشاهده پروفایل

پژوهشگر ارشد

• International Relations
• Intelligence Studies
• Security Cooperation
• +۳ مورد دیگر

Dr Thomas Maguire is a Visiting Fellow with the King's Intelligence and Security Group in the Department of War Studies at King's College London, and Assistant Professor of Intelligence and Security at Leiden University. His research focuses on intelligence-propaganda interactions and international security cooperation, particularly in Cold War Southeast Asia and counter-terrorism contexts. Education: PhD in International Relations (POLIS, University of Cambridge) MPhil in International Relations (POLIS, University of Cambridge) BA (Hons) in History (Durham University) Maguire's research examines the intersection of intelligence operations and propaganda dissemination in foreign policy contexts, with specialized focus on British and American covert action in Southeast Asia. He also investigates post-colonial security relationships and international counter-terrorism cooperation frameworks. His work spans historical analysis and contemporary security challenges. Maguire's publications demonstrate interdisciplinary research across public health, virology, and immunology, particularly addressing COVID-19 diagnostics, vaccine development, and immune responses. This reflects methodological versatility in addressing complex global security and health challenges through both historical analysis and biomedical research. Scientific Awards: Lisa Smirl Prize for best thesis (University of Cambridge) Maguire leads the Dutch Government-funded 'Sharing Secrets' project investigating intelligence disclosure decision-making. He teaches intelligence studies courses and co-convenes the Cambridge Intelligence Seminar. At Leiden, he coordinates undergraduate and postgraduate programs in Intelligence Studies and Crisis Management. Maguire previously served as Research Fellow at Darwin College and the Department of Politics and International Studies (University of Cambridge), and as John Garnett Visiting Fellow at the Royal United Services Institute focusing on East African security challenges.