Programmed Protein Modification Professors and Supervisors in Canada | ApplySharif

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استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۱-۱۵ از ۱۲۸ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Shyh-Dar Liمشاهده پروفایل

استاد

University of British ColumbiaCanada

Dr. Shyh-Dar Li is a Professor and Tong Louie Chair in Pharmaceutical Sciences at the University of British Columbia's Faculty of Pharmaceutical Sciences, where he also serves as Chair of Nanomedicine and Chemical Biology. With a BSc in pharmacy from National Taiwan University (1998) and PhD in pharmaceutical sciences from UNC Chapel Hill (2008), followed by postdoctoral training at UC San Diego's Moores Cancer Center (2009), Dr. Li has established himself as a leading researcher in advanced drug delivery systems. His research focuses on developing innovative nanomedicine platforms for targeted delivery of biological therapeutics including peptides, proteins, antibodies, and nucleic acids. Dr. Li's laboratory has pioneered several novel drug delivery approaches, particularly in lipid-based nanoparticles, phospholipid-free vesicles, and polymer systems for cancer immunotherapy, pain management, and protein delivery. His work bridges fundamental nanotechnology with translational applications for difficult-to-treat diseases. Analysis of his recent publications reveals a strong emphasis on tumor microenvironment modulation, endosomal escape mechanisms for nucleic acid delivery, and non-invasive delivery routes for protein therapeutics. His research demonstrates increasing sophistication in nanocarrier engineering, with recent work incorporating machine learning approaches to optimize nanoparticle design and expanding into immunomodulatory therapies that harness the body's immune system to fight cancer. Scientific Recognition: 2014 AFPC New Investigator Award 2013 AAPS New Investigator Award in Pharmaceutics and Pharmaceutical Technologies 2013 CIHR New Investigator Award 2013 CSPS Early Career Award 2012 Prostate Cancer Foundation Young Investigator Award Dr. Li's research program has been consistently supported by major Canadian funding agencies including CIHR, NSERC, and MITACS. He actively collaborates across disciplines and accepts graduate students into his research program, focusing on cutting-edge approaches to overcome biological barriers in drug delivery. His laboratory, the Laboratory of Targeted Drug Delivery and Nanomedicine, serves as a hub for innovation in pharmaceutical nanotechnology.

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David Vocadloمشاهده پروفایل

استاد

Simon Fraser UniversityCanada

David Vocadlo is a Distinguished Professor of Chemistry and Molecular Biology & Biochemistry at Simon Fraser University (SFU), holding the Canada Research Chair in Chemical Biology. His research focuses on Chemical Glycobiology, investigating carbohydrate-processing enzymes and developing chemical tools to study glycan roles in health and disease. His lab explores O-GlcNAc signaling, neurodegenerative disorders (e.g., Alzheimer’s, Parkinson’s), and enzyme inhibitors for therapeutic applications. Education: PhD from University of British Columbia (UBC), followed by a CIHR postdoctoral fellowship at UC Berkeley. Key roles include E.W.R. Steacie Memorial Fellow and Royal Society Fellow. Research highlights include O-GlcNAcase inhibitors for neuroprotection, glycan structure-function relationships, and enzyme activity imaging tools. Collaborates globally with experts in glycobiology and employs cutting-edge techniques like chemical synthesis, mass spectrometry, and live-cell imaging. Awards: Distinguished Professor title, Canada Research Chair, Royal Society Fellowship. Active in training researchers through SFU’s graduate programs, emphasizing interdisciplinary approaches. Lab members work on topics ranging from enzyme mechanisms to disease modeling.

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Christopher M. Overallمشاهده پروفایل

استاد

University of British ColumbiaCanada

Christopher M. Overall is a Full Professor at the University of British Columbia in the Faculty of Dentistry, Department of Oral Biological and Medical Sciences . He is also a Principal Scientist at the Centre for Blood Research and holds associate memberships in UBC's Biochemistry & Molecular Biology , Obstetrics and Gynecology , and Bioinformatics Graduate Program departments. As a Canada Research Chair Laureate , he pioneered the field of degradomics to study proteases in vivo. B.D.S., University of Adelaide Ph.D., University of Toronto Postdoctoral Fellowship, UBC (with Nobel Laureate Michael Smith) Dr. Overall’s research focuses on protease proteomics and systems biology , particularly degradomics to analyze protease substrates in diseases like COVID-19 and immunodeficiency . His work on matrix metalloproteinases has revealed new therapeutic strategies for inflammatory diseases and cancer . His 15 most recent articles (2015–2008) demonstrate expertise in TAILS proteomics , protein terminomics , and protease network analysis with applications in arthritis , antiviral immunity , and precision medicine . Scientific Awards 2022 Helmut Holzer Award 2018 Royal Society of Canada Fellow 2014 Tony Pawson Canadian Proteomics Award 2013 IADR Distinguished Scientist Award Dr. Overall has mentored 61 trainees , including 9 full professors with department chairs, and received the UBC John McNeill Mentorship Award (2023). He leads the HUPO Chromosome-centric Human Proteome Project and consults for Genentech and Novartis .

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Kibret Mequanintمشاهده پروفایل

استاد

Western UniversityCanada

Dr. Kibret Mequanint is a full Professor at Western University's Department of Chemical and Biochemical Engineering, with cross-appointments in Biomedical Engineering. Holding a PhD from University of Stellenbosch and postdoctoral experience at Technical University of Darmstadt and McMaster University, his research bridges polymer science, materials engineering, and life sciences with applications in Biomaterials , Tissue Engineering , and Regenerative Medicine . His work spans both fundamental and translational research in cell-material interactions , polymer biomaterial design , and therapeutic radiation dosimeters , with technologies transferred to commercial applications. Leading scholar and educator with awards from NSERC, CIHR, and Western University Fellow of: American Institute for Medical and Biological Engineering (AIMBE), Ethiopian Academy of Sciences, International Union of Societies for Biomaterials Science and Engineering, Canadian Academy of Engineering Extensive editorial and panel service for NSERC, CIHR, and international journals His research program has produced over 170 refereed publications, focusing on conductive hydrogels , bioadhesives , and vascular tissue engineering . Recent work on endoscopy-deliverable bioadhesives and snake venom-derived hemostatic gels has attracted global media attention. He has served in leadership roles at the Canadian Biomaterials Society and university governance bodies including Senate and Board of Governors.

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Nandika Bandaraمشاهده پروفایل

دانشیار

University of ManitobaCanada

Dr. Nandika Bandara serves as Associate Professor and Tier 2 Canada Research Chair in Food Proteins and Bioproducts at the University of Manitoba's Department of Food and Human Nutritional Sciences within the Faculty of Agricultural and Food Sciences. Her research program focuses on advancing sustainable protein technologies for food, materials, and bioproduct applications through integration of material science and nanotechnology. Education: CFS (Certified Food Scientist), Institute of Food Technologists / International Food Science Certification Council PhD (Food Science & Bioresource Technology), University of Alberta, Canada MSc (Food Science & Technology), University of Alberta, Canada BSc (Agriculture), University of Peradeniya, Sri Lanka Dr. Bandara's research explores protein and biopolymer-based nanostructures for bioactive delivery, sustainable protein extraction from Canadian crops and byproducts, and renewable biopolymers for food packaging and biomedical materials. Her lab investigates novel processing technologies' effects on protein structure-function relationships using advanced characterization techniques. Current projects include protein-lipid conjugation for nanodelivery systems, feather keratin-based wound-healing materials, and deep eutectic solvents for protein extraction. Her publication record demonstrates strong focus on plant protein valorization, nanodelivery systems, and functional materials. Key trends include development of electrospun nanofibers, protein-based packaging films reinforced with nanocellulose, and metabolomics approaches for bioactive compound analysis in Canadian berries. The research bridges fundamental protein chemistry with industrial applications in sustainable food systems. Awards and Honors: Outstanding Volunteer Service Award of the Food Chemistry Division at Institute of Food Technologists (IFT) - 2019/2020 Institute of Food Technologists (IFT) Emerging Leaders Network (ELN) Program finalist - 2019 Natural Science and Engineering Research Council (NSERC) of Canada Postdoctoral Fellowship - 2018 Agricultural Institute of Canada Foundations' (AICF) Karl C Iverson Agricultural Scholarship - 2016 MITACS Accelerate Graduate Scholarship - 2015 Queen Elizabeth II Doctoral Graduate Scholarship - 2015 American Oil Chemist Society Honored Student Award - 2015 Graduate Student Teaching Award of the Faculty of Graduate Studies and Research/ Faculty of Agricultural, Life and Environmental Sciences, University of Alberta - 2015 Alberta Innovates Technology Futures Graduate Student Doctoral Scholarship Dr. Bandara actively supervises graduate students through the University of Manitoba's Food and Human Nutritional Sciences program and holds an adjunct professorship at Dalhousie University. She serves as Associate Editor for Food Chemistry Journal and on the editorial board of Food Research International. Her research is supported by her Canada Research Chair position and industry partnerships focused on Canadian agricultural innovation. She directs the Food Proteins and Bioproducts Lab at the Richardson Centre for Food Technology and Research, which specializes in protein characterization, nanomaterial development, and sustainable extraction technologies. The lab collaborates with researchers across Canada and internationally to translate fundamental discoveries into industrial applications for food, packaging, and biomedical sectors.

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Anubhav Pratap-Singhمشاهده پروفایل

دانشیار

University of British ColumbiaCanada

Anubhav Pratap-Singh is an Associate Professor in the Food, Nutrition and Health department within the Faculty of Land and Food Systems at the University of British Columbia, where he holds the Food and Beverage Innovation Professorship. He leads the UBC Food Process Engineering Laboratory and his research spans environmental and natural resources economics, food chemistry (including fermentation), and natural resource management. His primary research interests focus on agri-food transformation, cold plasma food engineering, food processing, functional foods, heat transfer, high pressure mass transfer, novel non-thermal processing, nutraceuticals, pasteurization, and pulsed light sterilization. Dr. Pratap-Singh's work addresses fundamental questions about the impact of food processing on food quality, how technology can maximize desirable effects while minimizing deleterious ones to feed the growing global population, and how to ensure food safety and nutrition for all socioeconomic groups. His research program is organized around three main pillars: developing novel processing technologies for food preservation, developing technologies for food fortification, and modeling the human GI tract to understand the interaction between food processing and human health. He has made significant contributions to sonic mixing technology for thermal processing and pulsed UV light processing for food surface decontamination, with particular expertise in processing of liquid particulate matter. Dr. Pratap-Singh has received numerous prestigious awards throughout his career, including the Banting Fellowship (2016) and Green College Leading Scholar award (2017). His work has been recognized with the Young Entrepreneur Award (2009), IFTPS Graduate Scholar designation (2014), and Gold Medal from the Institute for Thermal Processing Specialists (2014), among other fellowships and honors. He is affiliated with the BioProducts Institute and Materials and Manufacturing Research Institute at UBC, and supervises graduate students in Food Science (MSc and PhD programs). His laboratory focuses on interdisciplinary research that addresses critical challenges in food science, with implications for feeding the projected 10 billion people by 2050 while countering negative public perceptions around processed foods.

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Nediljko Budisaمشاهده پروفایل

استاد

University of ManitobaCanada

Nediljko Budisa is a Professor and Tier 1 Canada Research Chair in Chemical Synthetic Biology and Xenobiology at the University of Manitoba's Faculty of Science, Department of Chemistry. His research program focuses on expanding the fundamental biochemical capabilities of living systems through genetic code engineering and synthetic biology approaches. Dr. Budisa's research spans multiple cutting-edge areas in synthetic biology, with particular emphasis on genetic code expansion , non-canonical amino acid incorporation , and protein engineering . His laboratory employs both classical biochemical techniques and advanced computational methods to develop orthogonal translation systems, engineer novel enzymes, and create synthetic cells with expanded biochemical repertoires. His work bridges chemistry, biology, and engineering to address fundamental questions about life processes while developing practical applications in biotechnology and medicine. Analysis of Dr. Budisa's publication record reveals a consistent trajectory of innovation in genetic code engineering, with recent work increasingly integrating machine learning approaches for protein design. His research spans from fundamental studies of protein structure-function relationships to applied research in metabolic engineering and antiviral strategies, demonstrating the versatility of synthetic biology approaches. Tier 1 Canada Research Chair in Chemical Synthetic Biology and Xenobiology Dr. Budisa leads an active research program supported by his Canada Research Chair position, with extensive collaborations across Canada and internationally. His work has resulted in numerous patents and commercial applications in biotechnology. He actively participates in the synthetic biology community through initiatives like Prairie iGEM BioExM and has delivered public lectures on methodological challenges in expanded genetic code research. His research is conducted through the Chemical Synthetic Biology and Xenobiology laboratory at the University of Manitoba, where his team explores the social, cultural, educational, ethical and philosophical aspects of synthetic biology alongside technical innovations, reflecting a comprehensive approach to advancing this transformative field.

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Jessica Sheldonمشاهده پروفایل

استادیار

University of SaskatchewanCanada

Jessica Sheldon is an Assistant Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan's College of Medicine. She joined the university in 2022 after completing postdoctoral training at Vanderbilt University Medical Center under the mentorship of Dr. Eric Skaar. Her educational background includes: PhD in Microbiology and Immunology (2015) from the University of Western Ontario MSc in Biology (2009) from Lakehead University HBSc in Biology (2006) from Lakehead University Dr. Sheldon's research focuses on the molecular pathogenesis of multidrug resistant bacteria, particularly Acinetobacter baumannii. Her work investigates the tug of war between host nutritional immunity and bacterial nutrient acquisition strategies. She examines how pathogens overcome host-imposed nutrient limitations, with special attention to metal ion homeostasis and iron acquisition mechanisms. Her laboratory employs techniques in bacteriology, molecular genetics, transcriptomics, and infection modeling to identify virulence mechanisms. Her publication record demonstrates consistent expertise in bacterial iron acquisition and host-pathogen interactions, with recent work increasingly focused on Acinetobacter baumannii's evasion of nutritional immunity during infection. The trajectory of her research shows progression from fundamental studies of iron acquisition in Staphylococcus aureus to translational work on a WHO-designated priority pathogen. Dr. Sheldon has established an active research program on multidrug resistant bacterial pathogens, with particular emphasis on understanding the molecular mechanisms that enable pathogens like Acinetobacter baumannii to overcome host defenses. Her work has significant implications for developing novel therapeutic strategies against antibiotic-resistant infections.

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Torsten Nielsenمشاهده پروفایل

استاد

University of British ColumbiaCanada

Professor Torsten Nielsen is a clinician-scientist at the University of British Columbia 's Department of Pathology & Laboratory Medicine (Faculty of Medicine), based at Vancouver General Hospital and BC Cancer . He directs UBC's MD/PhD Program , contributes to cancer clinical trials with the Canadian Cancer Trials Group , and chairs the international Connective Tissue Oncology Society 's Research Committee. Key affiliations: UBC, Vancouver General Hospital, BC Cancer, Molecular and Advanced Pathology Core Academic focus: Translational research in sarcomas and breast cancer His research prioritizes translating genomic discoveries into clinical diagnostics and treatments, particularly for synovial sarcoma , breast cancer subtypes , and tenosynovial giant cell tumors . He develops FDA-cleared molecular assays like the PAM50 (Prosigna) test and leads pan-Canadian precision oncology initiatives . Collaborative efforts include work with Stanford, Leiden, and DKFZ Heidelberg. Recent publications highlight advancements in epigenetic therapies , immune biomarker validation , and synovial sarcoma pathogenesis . His lab's work on CSF1/CSF1R signaling inspired new treatment strategies for joint-destructive tumors. Scientific Awards: Fellow, Canadian Academy of Health Sciences Fellow, Royal Society of Canada As director of UBC's MD/PhD Program, he trains future clinician-scientists. His lab team includes experts in epigenomics , proteomics , and mouse modeling . Current projects focus on precision oncology for sarcomas and Ki67 standardization in breast cancer.

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Scott Napperمشاهده پروفایل

استاد

University of SaskatchewanCanada

Dr. Scott Napper is a Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan, with a concurrent appointment as Senior Scientist at VIDO-Intervac. His work bridges structural biochemistry and immunology to address challenges in protein misfolding diseases, vaccine development, and host-pathogen signaling. Ph.D., Department of Biochemistry, 1999, University of Saskatchewan B.Sc. Honours, Department of Biochemistry, 1994, University of Saskatchewan Dr. Napper's research focuses on: Vaccine development for prion diseases and proteinopathies Kinome analysis for infectious disease mechanisms Peptide array technology for high-throughput signaling studies Science education outreach to secondary and undergraduate students Recent publications highlight his work in: Prion disease immunization strategies Host kinome responses to prebiotics Epitope immunogenicity prediction Comparative stress response analysis in livestock Scientific recognition includes: Three-time recipient of University of Saskatchewan Teaching Excellence Award His research program integrates computational approaches with experimental validation to identify therapeutic targets in: Infectious diseases of humans and animals Cancer signaling pathways Protein misfolding disorders Food contaminant toxicity

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Patrick O'Donoghueمشاهده پروفایل

دانشیار

Western UniversityCanada

Dr. Patrick O'Donoghue is an Associate Professor and Canada Research Chair in Chemical Biology at Western University's Department of Biochemistry, Faculty of Science. His research focuses on proteome diversity mechanisms through protein modifications and mistranslation, with implications for cancer and neurodegenerative diseases. Education: Ph.D. from University of Illinois, Postdoctoral training at Yale University Research highlights include pioneering genetic code expansion techniques for programmed protein modifications in human cells and developing fluorescent reporters to visualize translation errors. His work connects protein synthesis fidelity to disease pathways through tRNA mutant studies. Scientific Contributions: 2024 Mechanisms and Delivery of tRNA Therapeutics review in Chemical Reviews 2023 HARS Disease Therapeutics in Genes (Basel) 2022 Expanding Codon Size in eLife 2021 Fluorescent Mistranslation Reporters in Cells Contact: Office in Medical Sciences Building Room 388, Phone: 519.850.2373, Email: patrick.odonoghue@uwo.ca

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David Nataleمشاهده پروفایل

دانشیار

Queen's University at KingstonCanada

Dr. David Natale is an Associate Professor in the Department of Obstetrics and Gynaecology at Queen's University, with a cross-appointment in the Department of Biomedical and Molecular Sciences. His research focuses on placental development, particularly in pregnancies complicated by maternal disease (e.g., pre-eclampsia, diabetes) or exposures (e.g., cannabis). He uses mouse and rat models to study trophoblast stem cell differentiation and placental dysfunction. Education: Ph.D. in Physiology and Pharmacology (University of Western Ontario, 2003), B.Sc. (University of Western Ontario, 1996). Postdoctoral training under Dr. Jay Cross (University of Calgary) and later appointments include Assistant Professor roles at the University of Calgary (2008–2013) and University of California San Diego (2013–2019). Research interests span cell biology, regenerative medicine, and placental biology. His lab investigates how trophoblast populations and interactions are altered under compromised conditions, with recent emphasis on cannabinoid effects and maternal-fetal outcomes. Grants and funding include support from CIHR, NIH/NICHD, and UCSD/UCLA Diabetes Research Center. Current supervision includes postdoctoral fellow Samantha Benton. Labs/Teams: Queen's University placental research group, collaborations with human placenta research teams.

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Mads Kaernمشاهده پروفایل

دانشیار

University of OttawaCanada

Mads Kaern is an Associate Professor in the Department of Cellular and Molecular Medicine, specializing in synthetic biology, gene regulation, and systems biology. His research integrates computational modeling with experimental approaches to understand cellular processes and design genetic circuits for biomedical applications. Key areas of focus include epistasis analysis, gene expression variability, and the development of educational programs in BIOSTEM. Research interests span molecular mechanisms of gene regulation, synthetic biology applications, and quantitative analysis of genetic interactions. His work emphasizes interdisciplinary methods combining genomics, bioinformatics, and engineering principles to address complex biological questions. Publications highlight contributions to understanding cellular heterogeneity, improving DNA assembly techniques, and advancing therapeutic strategies through synthetic biology. Educational efforts include initiatives like iGEM-inspired programs to enhance undergraduate research and skill development in biotechnology.

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Keith Wheatonمشاهده پروفایل

استادیار

University of OttawaCanada

Dr. Keith Wheaton is an Assistant Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa , and serves as the Director of the Translational Molecular Medicine (TMM) Undergraduate Program . He is actively involved in curriculum development and science education, with a focus on active learning and student engagement in molecular medicine and aging biology. Education: BSc, Biochemistry – University of Guelph BEd, Adult Education – Brock University PhD, Biochemistry & Molecular Biology – University of Calgary Post-doctoral Research – University of Toronto & York University Research Interests: Dr. Wheaton’s research spans molecular biology , cellular senescence , and cancer biology , with a particular emphasis on the p53 tumor suppressor pathway and its role in aging and Hutchinson-Gilford Progeria Syndrome . His work has contributed to understanding how replication stress and genomic instability drive premature aging phenotypes. He is also a leader in science education , developing inquiry-based laboratory courses and integrating active learning strategies into biology and biochemistry curricula. He has taught in the Ottawa-Shanghai Joint School of Medicine and participates in the SEA PHAGES program, which engages undergraduates in genomics research. Scientific Contributions: Dr. Wheaton has published extensively in high-impact journals such as Molecular and Cellular Biology , Journal of Biological Chemistry , and Aging Cell . His work explores the molecular underpinnings of aging, the role of p53 in cellular senescence, and epigenetic regulation via ubiquitination and chromatin modification. Teaching & Outreach: He leads the TMM undergraduate program and teaches courses on aging, cancer biology, and molecular biology. He encourages undergraduate research and welcomes students to contact him for opportunities in the TMM program.

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Nicolas Bordenaveمشاهده پروفایل

دانشیار

University of OttawaCanada

Associate Professor Nicolas Bordenave is a cross-appointed member at the School of Nutrition Sciences, University of Ottawa, focusing on molecular interactions between macronutrients and phytonutrients in food systems. His research explores how these interactions affect glycemic response and phenolic bioavailability in cereal, fruit, and vegetable-based systems. Education: Ph.D. in Food Science (specific institution not mentioned in text) Prior Roles: Research positions at PepsiCo (Chicago, UK) and postdoctoral training at Purdue University's Whistler Center Professional Involvement: Board member of Feeding Tomorrow (IFT Foundation), contributor to Radio Canada's Moteur de recherche program His research spans starch/phenolic interactions , nutritional functionality , and biodegradable packaging materials , with applications in metabolic health and food formulation . Recent publications highlight trends in beta-glucan viscosity , starch digestibility , and phytonutrient delivery . Scientific contributions include methodological advancements in glycemic response assessment and chitosan-based packaging . Key collaborations include work with researchers at Purdue, PepsiCo, and industry partners. His lab investigates macronutrient-phytonutrient interactions , nutritional biochemistry , and functional food design . Current projects align with improving metabolic health through optimized food structures.

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