جست‌وجوی استاد و پژوهشگر

Matthew John Langمشاهده پروفایل

استاد

• Biophysics
• Immunology
• Molecular Physiology
• +۴ مورد دیگر

Matthew John Lang, PhD, is a Professor in both the Department of Chemical and Biomolecular Engineering and the Department of Molecular Physiology and Biophysics at Vanderbilt University. His research focuses on probing molecular and cellular machinery through functional measurements, employing methods like optical tweezers, single-molecule fluorescence spectroscopy, and molecular simulations. Key areas include T-cell receptor (TCR) mechanobiology, cellulose degradation mechanisms, and protease dynamics. He holds dual faculty appointments and has pioneered techniques to study mechanical signaling in immune cells and enzymatic systems. Contact: matt.lang@vanderbilt.edu . Research interests emphasize understanding how mechanical forces influence molecular interactions, particularly in T-cell activation and antigen recognition. His work integrates engineering, biophysics, and immunology to unravel fundamental biological processes. Recent studies highlight the role of mechanical load in TCR-pMHC interactions, asymmetric TCR framework motions, and cellulase processivity mechanisms. Publications span biophysical mechanisms of immune receptors, enzymatic degradation pathways, and protease function. His lab develops innovative tools like combined optical trapping and fluorescence imaging for single-cell analysis. Collaborations bridge disciplines, addressing challenges in cancer immunotherapy and bioenergy applications.

• Chemical Biology
• Catalysis
• Cyclic peptides
• +۶ مورد دیگر

Andrea Robinson is a Professor in the School of Chemistry at Monash University and a member of the Victorian Heart Institute (VHI). Her research focuses on chemical biology, catalysis, cyclic peptides, disulfide replacement, and renewable chemistry. She has led numerous high-impact projects, including advancements in drug-eluting medical devices, toxin structure-function analysis, and sustainable drug discovery. Notable achievements include the development of novel photo-angioplasty devices and dicarba peptide analogs with enhanced therapeutic efficacy. Research Interests Her work bridges organic synthesis, medicinal chemistry, and biotechnology. Key areas include: - Design of bioactive peptides and peptidomimetics for pain management and diabetes treatment - Sustainable chemical processes using renewable feedstocks - Metathesis-catalyzed peptide synthesis techniques - Development of photothermal cancer theranostics - Exploring fungal pigments and their industrial applications Awards - Dean’s Excellence in Teaching Awards (2017) - Faculty of Science, Dean's Excellence in Teaching Awards (2017) - From grave to cradle: Hunting new antimicrobials through sustainable drug discovery Award (2022) Grants & Projects - ARC Training Centre for Advanced Radiochemical Technologies (2024–2029) - Collaborations on 18F-radiolabeling for cancer diagnosis (University of Melbourne, Cyclotek) - Development of novel chelating agents for medical imaging (2025–2028) - Agricultural pest monitoring systems using night vision technology (DAFF-funded) Labs & Teams Dr. Robinson leads research teams within the School of Chemistry and collaborates with the Victorian Heart Institute. Her lab specializes in: - Peptide synthesis and characterization - Metathesis reaction development - Biomedical device prototyping - Sustainable chemical engineering processes

• Embryonic Stem Cells
• Embryogenesis
• 3D Structure of Membrane Proteins
• +۵ مورد دیگر

Michael Morris is a Senior Lecturer in Embryonic Stem Cells at the School of Medical Sciences, University of Sydney. He is affiliated with the Bosch Institute and a member of the Sydney Nano Institute. His research focuses on embryonic stem cell biology and membrane protein structure prediction. Key areas include understanding stem cell differentiation mechanisms, embryo development milestones, and computational tools for membrane protein modeling. Research interests span embryogenesis (blastocyst formation, gastrulation, neurogenesis) and membrane protein structural analysis. His work combines experimental embryology with bioinformatics, addressing challenges in regenerative medicine and drug discovery. Recent publications highlight L-proline's role in stem cell differentiation and embryo viability, biomaterial-based stem cell culture systems, and phage display for anti-cancer drug development. He advises students like Kate Carey on bovine oocyte maturation projects. Grants include equipment for laser microdissection systems and studies on ES cell differentiation. His interdisciplinary approach bridges stem cell biology, bioengineering, and computational biology.

Marcus Semtnerمشاهده پروفایل

استاد مهمان

• Neuroimmunology
• Physiology
• Neuroscience
• +۳ مورد دیگر

Prof. Dr. Marcus Semtner is a Visiting Professor at the Department of Biology, Chemistry, Pharmacy at Freie Universität Berlin, affiliated with the Institute of Biology and the Max Delbrück Center. His research focuses on neuroimmunology and the physiology of microglia, particularly their role in synaptic activity regulation, G protein-coupled receptor signaling, and interactions with neurons/astrocytes. He leads studies using advanced mouse models, such as GCaMP6m-expressing microglia, to dissect neuron-microglia communication in living brain tissues. Education details are not explicitly stated in the text, but his academic career includes collaborative research across institutions like the Max Delbrück Center. His work bridges immunology, neuroscience, and cell biology, with a focus on microglial dysfunction in neurodegenerative and genetic disorders like neurofibromatosis type 1 and autism spectrum disorder models. Research highlights include discoveries on microglial sensing of GABA and histamine signals, sex-specific microglial states, and the role of VGF-derived peptides in purinergic signaling. He co-developed novel techniques for in situ analysis of microglia, including Patch-seq and live imaging approaches. Teaching activities include leading the 'Neuroimmunology and Physiology of Microglia' course, emphasizing hands-on research integration. Collaborations with institutions like the Charité Berlin and international teams (e.g., with Dr. Dieter H. Gutmann in St. Louis) are central to his work.

Thomas Langerمشاهده پروفایل

استاد

• Mitochondrial Biology
• Cellular Aging
• Age-related Diseases
• +۶ مورد دیگر

Prof. Dr. Thomas Langer leads the Department of Mitochondrial Proteostasis at the Max Planck Institute for Biology of Ageing. His research focuses on mitochondrial proteases, their role in cellular aging, and age-related diseases. He investigates how mitochondrial dynamics, lipid trafficking, and proteostasis impact neurodegeneration and metabolic disorders. Key Grants: DFG CRC 1218 & 1403, German-Israel MitoBalance, Marie Sklodovska-Curie ITN Remix Notable Awards: Humboldt Foundation & EMBO Postdoctoral Fellowships His work spans mitochondrial membrane dynamics, lipid homeostasis, calcium signaling, and stress responses. Recent studies highlight connections between OMA1 protease activation, ferroptosis, and cardiomyopathy, as well as prohibitin-mediated membrane organization in neurodegenerative diseases. Collaborative projects with institutions in Germany and Japan further expand his research impact. Publications show consistent contributions to journals like Nature , Cell Metabolism , and Nature Cell Biology , with recurring themes in mitochondrial fragmentation, metabolic reprogramming, and neuroprotection. His lab trains a large cohort of PhD students and postdocs, fostering next-generation scientists in mitochondrial biology.

Xinyun Jianمشاهده پروفایل

پژوهشگر ارشد

• Natural Products Discovery
• Antibiotics
• Anti-cancer Drugs
• +۳ مورد دیگر

Xinyun Jian is a Research Fellow in the Department of Biochemistry & Molecular Biology at Monash University. Their research focuses on the chemistry and biology of bioactive natural products, including antibiotics, anticancer agents, and agrichemicals. They employ interdisciplinary approaches such as genomics-driven discovery, biosynthetic pathway elucidation, and bioengineering to create novel natural product derivatives. Education: PhD in Chemistry (2014), University of Warwick, UK MSc in Microbial and Biochemical Pharmacy (Bioengineering of aminoglycosides), Wuhan University, China Research Interests: Genomics-driven discovery of novel bioactive natural products Mechanistic characterization of enzymes in biosynthesis pathways Engineering biosynthetic pathways for antibiotic diversification Recent Projects: Primary Chief Investigator (2025–2026): 'Unlocking the Potential of Soil Bacteria to Combat Drug-Resistant Fungal Pathogens' Publications Trends: Recent work emphasizes enzymatic mechanisms in polyketide and nonribosomal peptide systems, with a focus on antibiotic skeletal diversification, glycodiversification of aminoglycosides, and HDAC inhibitor design. Articles highlight interdisciplinary methods to address antibiotic resistance and anticancer drug development. Labs/Teams: Active in Monash University's Biochemistry & Molecular Biology department, collaborating on microbial natural product research and enzymatic biosynthesis.

Sebastian Demkowiczمشاهده پروفایل

دانشیار

• Organic Chemistry
• Medicinal Chemistry
• Enzyme Inhibitors
• +۴ مورد دیگر

Sebastian Demkowicz is an Associate Professor at Gdańsk University of Technology's Faculty of Chemistry, Department of Organic Chemistry, and currently serves as Vice-Dean for Student Affairs. His academic progression includes roles as assistant (2009–2010), assistant professor (2010–2018), and associate professor since 2018. He earned his PhD in Chemical Sciences (2009) and habilitation (2018) from Gdańsk Tech. Research focuses on drug design targeting breast cancer via steroid sulfatase (STS) inhibitors, organophosphorus chemistry, and mechanochemical synthesis. Key contributions include novel enzyme inhibitors (e.g., STS inhibitors based on triazole, coumarin, and flavone scaffolds) and studies on electron attachment mechanisms in nucleic acids. Publications (45+) span Journal of Medicinal Chemistry , European Journal of Medicinal Chemistry , and Scientific Reports . Awards include Rector Awards for scientific excellence (2009, 2016, 2018). He leads projects on drug discovery and acts on university committees (e.g., Faculty Recruitment Committee, Disciplinary Committee). Labs/teams: Active in organic synthesis and medicinal chemistry labs at Gdańsk Tech, collaborating on STS inhibitor development and radiation chemistry studies.

Merran Findlayمشاهده پروفایل

پژوهشگر ارشد

• Nutrition and Dietetics
• Clinical Nutrition
• Nutritional Science
• +۳ مورد دیگر

Dr. Merran Findlay is a Senior Research Fellow at UNSW Sydney and Clinical Associate Professor at The University of Sydney, specializing in cancer nutrition for over 25 years. She serves as Board Director for the Clinical Oncology Society of Australia and Australia and New Zealand Head and Neck Cancer Society. Her work bridges clinical practice with implementation science in nutrition assessment, malnutrition management, and value-based healthcare. Senior Research Fellow – Living Better With and After Cancer, Maridulu Budyari Gumal (SPHERE) Cancer Clinical Academic Group Clinical Appointments: Royal Prince Alfred Hospital, Chris O’Brien Lifehouse Leadership Roles: Co-founder of Implementation Science networks at UNSW and The University of Sydney Her research focuses on nutrition interventions in head and neck cancer, sarcopenia assessment, and evidence-based guideline implementation. She explores how nutritional status affects clinical outcomes, treatment complications, and healthcare costs through international multicenter studies and digital health innovations. Current research trends show strong emphasis on head and neck cancer nutrition , sarcopenia biomarkers , and implementation science for guideline adoption. Her work spans nutrition assessment , enteral nutrition , and health services research , with recent articles addressing AI integration in quality indicators and sarcopenia severity quantification. Dr. Findlay leads implementation programs like the Sydney Health Partners Implementation Science Program and conducts extensive audits including INFORM (International Nutrition Audit in Foregut Tumors). Her collaborative efforts involve developing CT-based sarcopenia metrics and optimizing nutrition counseling frequency during cancer treatment.

• Mass Spectrometry
• Lipidomics
• Metabolomics
• +۳ مورد دیگر

Reuben Young is an Associate Research Fellow at the University of Wollongong's School of Chemistry and Molecular Bioscience within the Faculty of Science, Medicine and Health. His work focuses on advancing mass spectrometry-based technologies for lipidomics and metabolomics, particularly in studying disease mechanisms such as osteoarthritis, cancer, and neurodegenerative conditions. Key research themes include spatial metabolite imaging, lipid isomer characterization, and development of novel analytical techniques like ozone-induced dissociation and MALDI-2 oversampling. His research has been supported by grants such as 'Sparking and fading: Spatially linking the complex metabolic activities of neurotransmitters and lipids during cell death' (2023-2024), investigating neurodegeneration mechanisms, and an equipment grant for mass spectrometry facility maintenance (2023). He collaborates extensively with peers globally, evidenced by co-authorships on over 30 publications. Recent publications emphasize lipidomic profiling in cancer progression, enzymatic activity mapping in osteoarthritis, and peptide-based cancer therapies. His work bridges fundamental analytical chemistry with biomedical applications, contributing to both instrumentation innovation and disease biomarker discovery.

Olayemi O. Adeoyeمشاهده پروفایل

عضو هیئت علمی

• Vascular Biology
• Hypoxia Responses
• Drug Metabolism During Pregnancy
• +۳ مورد دیگر

Olayemi O. Adeoye, MBBS, PhD, MPH holds dual academic appointments at Loma Linda University as Assistant Professor in the Physiology Division of the School of Medicine and Associate Professor in the Pharmaceutical and Administrative Sciences department of the School of Pharmacy. His career spans clinical medicine, public health, and physiological research with a focus on vascular adaptation mechanisms. His educational background includes: MBBS (Bachelor of Medicine & Surgery) from University of Lagos (2004) Postbaccalaureate Certificate from Loma Linda University (2007) MPH (Master of Public Health) from Loma Linda University (2008) PhD in Physiology from Loma Linda University (2013) Adeoye's research centers on vascular smooth muscle responses to hypoxia, particularly in fetal development and pregnancy contexts. His work investigates cytochrome P450 regulation during pregnancy, glucocorticoid receptor homeostasis in obese pregnancies, and cerebrovascular adaptation mechanisms. Current projects include molecular markers of steroid sensitivity in fetal cells (2020-2025) and the Federal Hispanic Center of Excellence in Pharmacy (2022-2027). His 22 publications since 2010 demonstrate consistent contributions to vascular physiology, with recent work expanding into clinical guideline evaluation and cancer pharmacology. His scholarly output reveals strong focus areas: Chronic hypoxia effects on fetal cerebrovascular function (2013-2017) VEGF receptor-mediated vascular remodeling (2010-2014) Neuropeptide Y and sympathetic nervous system roles in hypoxic adaptation (2014-2015) Recent expansion into pregnancy-related metabolic research (2023-2024) Adeoye actively participates in professional development through conferences including Experimental Biology (2018), Meharry Translational Research Center Health Disparities Conference (2016), and Federation of Societies of Experimental Biology meetings. His teaching portfolio includes foundational biomedical science courses (RXPS 542/783) across multiple summer sessions from 2020-2025, reflecting commitment to medical and pharmacy education.

• Structural Glycoscience
• NMR Spectroscopy
• Structure-guided Drug Design
• +۱۲ مورد دیگر

Associate Professor Thomas Haselhorst is a research leader at the Institute for Biomedicine and Glycomics , Griffith University, with a distinguished career in structural glycoscience and NMR spectroscopy . His expertise spans glycan-virus interactions , structure-guided drug design , and targeted drug delivery for diseases like SARS-CoV-2, HIV, and Non-Hodgkin’s Lymphoma. He has pioneered NMR methodologies to study glycan-cell receptor dynamics and developed glycan-based prebiotics to reduce Campylobacter jejuni in poultry. Education: Doctor of Natural Science (Dr rer nat), Medical University Lübeck (1996-1999) Research Interests: Structural analysis of glycan-pathogen interactions Design of prebiotic supplements for agricultural applications Development of glycan-targeted therapies for viral and fungal diseases Innovative NMR approaches for ligand-binding studies Article Trends: Focus on glycan-virus binding mechanisms (SARS-CoV-2, Influenza, Rotavirus) Structural characterization of antifungal and anticancer agents Methodological advancements in NMR-based glycan analysis Exploration of glycan-glycan crosslinking in disease Scientific Awards: ARC Future Fellow Alexander von Humboldt Fellow Supervision: Principal/Associate Supervisor for 15+ doctoral students Research on glycan roles in HIV, cancer, and pathogenic fungi Collaborative Networks: International partnerships in glycomics and virology Multi-million-dollar grants from ARC, NHMRC, and industry

• Supramolecular Chemistry
• Organic Chemistry
• Materials Science
• +۴ مورد دیگر

Prof. Laura Baldini is an Associate Professor at the University of Parma's Department of Chemical, Life and Environmental Sustainability Sciences. She holds a PhD in Chemical Sciences (2002) from the University of Parma and has held postdoctoral positions at Yale University (2002–2003) and the University of Sheffield (2000–2001). Her research focuses on Supramolecular Chemistry, including calixarene and porphyrin synthesis, molecular recognition, and applications in catalysis, environmental remediation, and pharmaceuticals. Education: Bachelor's in Chemistry (cum laude), University of Parma (1998) PhD in Chemical Sciences, University of Parma (2002) Research interests emphasize calixarene functionalization for molecular recognition of metal ions, biomolecules, and CO₂ capture. Applications span non-viral gene therapy vectors, luminescent devices, and radioactive waste purification. Recent work explores energy/charge transfer phenomena in calixarene-based systems. Teaching includes courses on Supramolecular Chemistry (Master's) and Organic Chemistry Laboratory II (Bachelor's), delivered since 2015. She organized the 9th National Congress of Supramolecular Chemistry (2009) and has over 40 peer-reviewed publications.

Rebecca Bullerمشاهده پروفایل

استاد

• Biocatalysis
• Enzyme Engineering
• Computational Protein Design
• +۵ مورد دیگر

Prof. Dr. Rebecca Buller is a leading researcher at the ZHAW School of Life Sciences and Facility Management , specializing in biocatalysis and enzyme engineering. Her work bridges computational methods with industrial applications, focusing on sustainable chemical synthesis and food safety. Research Interests : Biocatalysis, enzyme design, halogenation reactions, mycotoxin reduction, 3D bioprinting inks, machine learning-driven enzyme optimization. Key Projects : National Competence Center of Research Catalysis , Microbial Epimerases for Drug Synthesis , Reduction of Mycotoxins in Food Streams , and Excelzyme (university-industry collaboration). Publications highlight advancements in: Temperature-induced enzyme stabilization (2025) Computational protein design (2024) Mutational path enrichment (2024) Mycotoxin detoxification (2024) Industrial biocatalysis (2023-2024) Collaborations span institutions like the University of Basel, ETH Zurich, and industry partners in Switzerland. Her work integrates computational analysis, directed evolution, and real-world applications in pharmaceuticals and food safety.

Luis Moroderمشاهده پروفایل

استاد پژوهشی

• Peptide Chemistry
• Bioorganic Chemistry
• Protein Chemistry
• +۳ مورد دیگر

Prof. Dr. Dr. hc. Luis Moroder was a renowned scientist and long-time leader at the Max Planck Institute of Biochemistry in Martinsried. He held positions as a researcher in the Peptide Chemistry department (1975–1991) and later as head of the Bioorganic Chemistry research group (1991–2005). His work focused on peptide synthesis, protein folding mechanisms, and structure-based drug design for enzyme inhibitors in diseases like cancer. Moroder published over 600 articles, co-edited books, and served as Editor-in-Chief of the Journal of Peptide Science . Research Contributions: Pioneered studies on gastrointestinal hormones, collagen triple helix dynamics, and light-switchable peptides. Developed synthetic methods for peptide chemistry and enzyme inhibition strategies. Awards: Honorary doctorate and multiple scientific prizes for contributions to bioorganic chemistry and drug design. Legacy: Organized the Institute’s peptide synthesis service and mentored numerous researchers. His work remains foundational in peptide science and structural biology. His research bridged chemistry and biology, addressing complex questions about protein function and disease mechanisms through innovative chemical approaches.

Ola Nilsenمشاهده پروفایل

استاد

• Inorganic Materials Chemistry
• Atomic Layer Deposition (ALD)
• Energy Storage Materials
• +۴ مورد دیگر

Ola Nilsen is a Professor of Inorganic Materials Chemistry at the University of Oslo, affiliated with the Department of Chemistry within the Faculty of Mathematics and Natural Sciences. His research focuses on atomic layer deposition (ALD) and molecular layer deposition (MLD), specializing in the synthesis and application of thin films for energy storage, biocompatible surfaces, and advanced materials. Key areas include solid-state batteries, functional oxides, and hybrid materials. He leads the NAFUMA thin film research group and has designed over 10 ALD reactors for diverse substrate applications. Beyond academia, he co-founded the Nano School outreach program, teaching nanotechnology to high school students. Research Interests: Atomic Layer Deposition (ALD) and Molecular Layer Deposition (MLD) Functional thin films for energy storage (e.g., Li-ion batteries) Bioactive surfaces and medical materials Crystal growth and thin film characterization Novel precursor development for ALD/MLD Articles Highlight Trends in: ALD-based battery materials (e.g., Si-based electrodes) Biocompatible hybrid films (e.g., Titaminates) Photoelectrocatalytic materials for water splitting Anion-ordered oxide chlorides Outreach and Education: Annual Nano School workshops for high schoolers Public lectures on nanotechnology and battery technology Key Collaborations: SOLARIS (solar photochemical H₂ projects), NAFUMA (nanostructures and functional materials), and international teams via UiO's open-access workshop infrastructure.