جستجوی استاد راهنمای دانشگاهی

Vadim Cherezov, the Ester Dornsife Chair in Biological Sciences and Professor at the University of Southern California (USC), leads groundbreaking research in membrane protein structure and function. Affiliated with the Bridge Institute, Department of Chemistry, and Michelson Center for Convergent Bioscience, his work focuses on GPCRs, ion channels, and transporters—critical targets for drug discovery. His team leverages advanced techniques like Lipidic Cubic Phase (LCP) and Serial Femtosecond Crystallography (SFX) at XFEL facilities to solve high-resolution structures under physiological conditions. Institutional Affiliations: Bridge Institute, USC Michelson Center, Department of Chemistry, Department of Pharmacology and Pharmaceutical Sciences. Key Collaborations: Katritch Lab, Kuhn Lab, NIH, European XFEL. His research explores the role of lipids in modulating GPCR function, addressing diseases like Alzheimer’s, diabetes, and cancer. By solving the structure of the A 2A adenosine receptor via sulfur SAD phasing at XFEL, Cherezov’s lab demonstrated de novo phasing without heavy atoms. This breakthrough enables structural studies of previously intractable membrane proteins. Scientific Awards & Grants: NIH R01 GM108635, U54 GM094618, U54 GM094599, R01 GM095583 Science Signaling Breakthroughs of the Year (2014) Cherezov mentors a dynamic team, including postdocs (e.g., Dong-Gyun Kim), graduate students (e.g., Behnaz Davoudinasab), and alumni (e.g., Benjamin Stauch at Eli Lilly, Nairie Michaelian at Genentech). His lab’s publications span Nature , Science , and Cell , with recent work on Science Advances (2025) addressing ABEL-FRET for GPCR dynamics.

• Membrane Protein Structure and Function
• G Protein-Coupled Receptors (GPCRs)
• Lipid-Protein Interactions
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Jennifer A. Smith, PhD, MPH is an Associate Professor of Epidemiology and Research Associate Professor of Survey Research at the University of Michigan School of Public Health . She also serves as Director of the Certificate in Public Health Genetics and is Assistant Director of the Cohort Development working group for U-M Precision Health and the Michigan Genomics Initiative. Education: PhD, Epidemiology, University of Michigan (2011) MA, Statistics, University of Michigan (2009) MPH, Health Management and Policy, University of Michigan (2005) BS, Biological Sciences, Cornell University (2001) Research Interests: Dr. Smith is a genetic epidemiologist whose work lies at the intersection of genomics, epigenomics, and social epidemiology . She investigates how genetic, epigenetic, and transcriptomic variation influence age-related chronic diseases such as cardiovascular disease, hypertension, dementia, and cognitive decline. A major focus is understanding how social, psychosocial, and neighborhood determinants interact with genetic risk to shape socioeconomic and racial/ethnic health disparities . Research Projects: Her work leverages large, multi-ethnic cohorts including the Health and Retirement Study (HRS), GENOA, SWAN, MESA, and LASI. She is a core faculty member of the Center for Social Epidemiology and Population Health (CSEPH) , and affiliated with MiCDA, the Center for Midlife Science, and the PNG Program . She also collaborates with leading consortia such as CHARGE and TOPMed. Selected Trends in Publications: Her recent work (2022–2025) emphasizes epigenetic mediation of social determinants on cardiovascular and cognitive health, polygenic risk scores across diverse ancestries , and multi-omics integration in aging and disease. These studies consistently highlight how social environments and genetic architecture jointly influence health outcomes across populations. Contact: Email: smjenn@umich.edu Office: 734-615-9455 Address: 2631 SPH I, 1415 Washington Heights, Ann Arbor, MI 48109

• Genetic Epidemiology
• Epigenomics
• Aging
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Dr. Yolanda Gil is a Research Professor in Computer Science and Spatial Sciences at the University of Southern California, where she serves as Principal Scientist and Senior Director for Strategic Initiatives in Artificial Intelligence and Data Science at the Information Sciences Institute (ISI). She is also the Director of AI and Data Science Initiatives in the Viterbi School of Engineering and leads the USC Center for Knowledge-Guided Interdisciplinary Data Science (CKIDS). Dr. Gil received her Licenciatura in Computer Science from the Polytechnic University of Madrid and her M.S. and Ph.D. in Computer Science from Carnegie Mellon University, with a focus on artificial intelligence and cognitive science. Her research focuses on developing AI approaches that use knowledge to accelerate scientific discovery processes. Her key research interests include knowledge capture and representation, semantic workflows, ontology tools, scientific discovery methods, task-based collaboration, provenance tracking, knowledge networks, reproducibility in science, and machine learning for data analysis. She collaborates with scientists across multiple domains to improve how scientific knowledge is created, shared, and used. Dr. Gil's work has significant impact across multiple scientific domains including climate science, neuroscience, and omics research. Her projects demonstrate her commitment to building knowledge-guided systems that transform how scientists conduct research. She has pioneered approaches to capture the provenance of scientific experiments and to automate the analysis of complex scientific data. Fellow of the Association for Computing Machinery (ACM) Fellow of the Association for the Advancement of Science (AAAS) Fellow of the Institute of Electrical and Electronics Engineers (IEEE) Fellow of the Association for the Advancement of Artificial Intelligence (AAAI) 24th President of the Association for the Advancement of Artificial Intelligence Co-chair of the CRA/AAAI 20-Year Artificial Intelligence Research Roadmap for the US Initiator and leader of the W3C Provenance Group that resulted in a widely-used standard for web trust As an educator and leader, Dr. Gil directs the Data Science Program in Computer Science and serves as Co-Director of multiple joint MSc programs including Communication Data Science, Spatial Data Science, Environmental Data Science, Public Policy Data Science, and Healthcare Data Science. She also leads the new dual degree USC-Tsinghua University on Communication Data Science. Her leadership extends to mentoring numerous students and researchers in AI and data science. Through the USC Center for Knowledge-Guided Interdisciplinary Data Science (CKIDS), Dr. Gil organizes DataFest events each semester, fostering collaboration and innovation in data science across disciplines.

• Knowledge capture
• Semantic Workflows
• Ontology Tools
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Andrea Montanari is a Professor of Mathematics and Statistics at Stanford University, affiliated with the Department of Mathematics and Statistics. His research focuses on high-dimensional statistics, machine learning theory, optimization algorithms, and statistical physics, with applications to neural networks and complex systems. He has contributed extensively to understanding generalization in overparametrized models, spin glass theory, and algorithmic methods like approximate message passing. His work bridges theoretical computer science and mathematical physics, addressing challenges in data analysis and learning from high-dimensional datasets. Notable themes include analyzing neural network dynamics, optimizing high-dimensional landscapes, and developing efficient algorithms for sparse and low-rank matrix estimation. Montanari’s publications explore topics such as the interplay between statistical and computational limits, the behavior of gradient-based methods, and the theoretical foundations of modern machine learning. His recent research demonstrates a focus on fundamental questions in learning theory, including the study of phase transitions in statistical estimation, the role of overparametrization in generalization, and the mathematical underpinnings of contemporary algorithms. While no specific awards are listed here, his contributions reflect significant impact in interdisciplinary fields.

• High-dimensional statistics
• Machine learning theory
• Statistical physics
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Mike Kirby is a Professor at the Kahlert School of Computing, University of Utah. He also holds adjunct professorships in the Department of Bioengineering and the Department of Mathematics. His current roles include leadership in scientific computing and informatics initiatives, including former directorships of the Utah Informatics Initiative (2019-2023) and the Multi-Scale Multidisciplinary Modeling of Electronic Materials (MSME) Collaborative Research Alliance (2016-2022). He has extensive experience in strategic research initiatives, including serving as Assistant Vice President for Research (2024-2025). Education: Dr. Kirby earned a PhD in Applied Mathematics (2002) and MS in Computer Science (2001) from Brown University, and a BS in Applied Mathematics and Computer Science from Florida State University (1997). Research Interests: Focus on large-scale scientific computing, physics-informed machine learning, computational science and engineering, high-order numerical methods, and visualization. His work bridges applied mathematics and computer science to address real-world engineering challenges. Publications: Over 150 peer-reviewed articles, including high-impact contributions in journals like Journal of Computational Physics and SIAM Journal on Scientific Computing . Recent work emphasizes machine learning for differential equations, topology optimization under uncertainty, and multi-fidelity modeling. Awards: Recognized for leadership in computational science and informatics, including contributions to University of Utah’s Clery Compliance Program. Advising & Grants: Supervised over 50 graduate students and postdocs. Secured funding from NSF, DOE, and industry partnerships, totaling millions in research grants. Active in interdisciplinary collaborations across engineering, materials science, and medicine. Labs/Teams: Scientific Computing and Imaging (SCI) Institute, Utah Informatics Initiative, and the Center for Multiscale Modeling of Electronic Materials (MSME).

• Scientific Computing
• Physics-Informed Machine Learning
• Computational Science and Engineering
• +۴ مورد دیگر

Raphael Franzini serves as Associate Professor of Medicinal Chemistry at the University of Utah, actively contributing to the Biological Chemistry PhD Program. His research pioneers innovative chemical approaches for therapeutic development, with dual focus on DNA-encoded library technologies and bioorthogonal drug delivery systems. His educational foundation includes an M.S. from the Swiss Federal Institute of Technology (Lausanne) and a Ph.D. from Stanford University. This training underpins his group's multidisciplinary methodology combining organic synthesis, bioconjugation, computational modeling, and advanced imaging techniques. Dr. Franzini's research program centers on two transformative areas: First, advancing DNA-encoded library screening through computational integration to identify leads for challenging targets like Tankyrase and Sirtuin 6, with recent work addressing false negatives in machine learning prediction. Second, developing novel bioorthogonal release chemistry using isonitrile-tetrazine reactions for spatiotemporally controlled drug activation, validated in zebrafish models. His group emphasizes both technological innovation and therapeutic translation, with chemistry designed to minimize off-target effects in solid tumors. Analysis of his 15 most recent publications reveals escalating integration of computational methods with experimental library screening, alongside refinement of bioorthogonal release kinetics. The work spans chemical biology, medicinal chemistry, and pharmaceutical sciences, with growing emphasis on machine learning for library data interpretation and in vivo validation of drug-release systems. Dr. Franzini maintains an active research laboratory that provides comprehensive training in cutting-edge drug discovery methodologies. His group culture prioritizes both scientific innovation and researcher development, with projects spanning from fundamental reaction kinetics to therapeutic applications. The lab's infrastructure supports organic synthesis, molecular imaging, and computational analysis for advancing precision therapeutics.

• Drug Discovery
• Medicinal Chemistry
• Bioorthogonal Chemistry
• +۳ مورد دیگر

Shili Lin is a Professor of Statistics at The Ohio State University's Department of Statistics, within the College of Arts and Sciences. She joined the faculty in 1995 after serving as the Neyman Visiting Assistant Professor at the University of California, Berkeley. Her expertise spans statistical genomics, bioinformatics, high-dimensional data analysis, Bayesian statistics, and Monte Carlo methods. Lin collaborates extensively with medical researchers to address challenges in genomic data such as ultra-high dimensionality, complex dependencies, and sparsity, focusing on diseases like cancer, multiple sclerosis, tuberculosis, and diabetes. She has contributed to developing computational tools for analyzing chromatin interactions, methylation patterns, and metagenomic samples. Lin holds a PhD from the University of Washington (1993). Her professional roles include serving as an Associate Editor for Biometrics , Statistical Applications in Genetics and Molecular Biology , and Statistics in Biosciences , as well as an Editorial Board member for Genetic Epidemiology . She is a standing member of NIH's Biostatistical Methods and Research Design Study Section and has served on multiple NSF and NIH grant review panels. Additionally, she is President Elect of the Caucus for Women in Statistics and has been a member of the ASA Committee on AAAS representation for six years. Her research interests emphasize statistical methodologies tailored to genomic data, including model selection, epigenetic analysis, and integrative approaches for multi-omics data. Lin's work often combines theoretical advancements with practical applications, such as predicting relapse in immune-mediated disorders and improving imputation techniques for single-cell Hi-C analysis. She has pioneered software tools like TopKLists and GrammR to facilitate ranked list aggregation and metagenomic data analysis. Lin's scientific accolades include ASA Fellowship (2004), AAAS Fellowship (2009), and membership in the International Statistical Institute (2014). Her contributions to statistical genetics and epigenomics have been recognized through grants and editorial leadership roles. While her research group focuses on cutting-edge methods, no formal advisees or students are explicitly listed in the provided materials.

• Statistical Genomics and Bioinformatics
• High-Dimensional Data Analysis
• Bayesian Statistics
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Yize Zhao is an Associate Professor in the Department of Biostatistics at Yale School of Public Health and an Associate Professor in the Department of Biomedical Informatics & Data Science at Yale University. She holds affiliations with multiple Yale research centers including the Yale Center for Analytical Sciences, Yale Alzheimer's Disease Research Center, Yale Wu Tsai Institute, Yale Center for Brain and Mind Health, and Yale Computational Biology and Bioinformatics. Dr. Zhao's research focuses on developing statistical and AI methods to analyze large-scale complex biomedical data including medical imaging, genomics, and electronic health records. Her methodological expertise spans Bayesian statistics, feature selection, predictive modeling, data integration, missing data analysis, and network analysis. Her research interests span multiple biomedical domains with a strong focus on mental health, psychiatry, neurodegenerative diseases, and aging. Her recent work includes brain-to-behavior modeling, multi-layer biomedical networks, imaging genetics and genomics, and the integration of multi-modal biomedical data with real-world data. Dr. Zhao's work has resulted in numerous high-impact publications, with recent research focusing on Alzheimer's disease, brain network analysis, and advanced statistical methods for neuroimaging. Her publications show a strong trend toward integrating multi-modal data sources and developing sophisticated statistical approaches to address complex biomedical questions. Thelma and Marvin Zelen Emerging Women Leaders in Data Science Award from the Institute of Mathematical Statistics (IMS) COPSS Emerging Leader Award from the Committee of Presidents of Statistical Societies (COPSS) YSPH Investigator Research Award Yale Alzheimer's Disease Research Center Research Scholar Award Elected member of the International Statistical Institute Dr. Zhao serves as an Associate Editor for Biometrics and is a standing member of the NIH Biodata Management and Analysis (BDMA) study section. Her research is supported by multiple NIH grants, highlighting the significance and impact of her work in biostatistics and biomedical data science.

• Biostatistics
• Data Science
• Neuroimaging Analysis
• +۷ مورد دیگر

Matteo Bolner is a Post-Doctoral Research Fellow at the University of Bologna's Department of Agricultural and Food Sciences, specializing in livestock genomics and metabolomics. He holds a PhD in Agricultural and Food Sciences (defended March 2025) and an International Master in Bioinformatics from the University of Bologna. His research integrates genomic and metabolomic data to improve livestock sustainability, particularly in pig production systems. Key focuses include identifying metabolic pathways influencing production traits, analyzing pig viromes for disease outbreaks, and leveraging big data for One Health applications. His educational background includes a Biological Sciences degree (2018) and a bioinformatics master's (2021). He interned at CINECA's SCAI department, focusing on HPC software containerization. Current affiliations include membership in the Animal and Food Genomics group, where he explores genomic solutions for breed conservation and sustainable production. Research trends in his articles emphasize multi-omics integration to understand pig metabolism, stress responses, and breed-specific adaptations. He also applies genomics to authenticate food products and enhance conservation strategies for endangered livestock breeds like the Mora Romagnola pig. His work bridges animal science, computational biology, and agricultural sustainability. Notable contributions include developing genomic tools for honey bee population analysis and creating a catalog of mitochondrial insertions in pig genomes. Future directions involve advancing metabolomics-based precision livestock farming and applying big data analytics to livestock One Health challenges.

• Livestock Systems
• Animal Breeding
• Genetics
• +۳ مورد دیگر

Luca Sebastiani is a Full Professor in Horticultural Sciences (AGR/03) at Scuola Superiore Sant'Anna in Pisa, Italy, since 2014. He currently coordinates the PhD Course in AgroBioSciences and has previously served as Director of the Institute of Life Sciences (2016-2021). His academic career includes roles as Associate Professor (2002-2014) and Assistant Professor (1998-2002) at the same institution. PhD in Plant Biology from Scuola Superiore Sant'Anna (1996) MSc in Agricultural Sciences from University of Pisa (cum laude, 1991) Postdoctoral research in agricultural biotechnology (1996-1998) Research Interests: Focus on plant-environment interactions, particularly abiotic and biotic stress responses in crops. Key areas include: Physiological and molecular responses to climate change stressors Nutraceutical enhancement of food crops Plant germplasm conservation using molecular markers Agriculture 4.0 integrating AI, IoT, and robotics Phytoremediation using poplar and Brassica species Scientific Contributions: His work bridges molecular mechanisms (aquaporin function, heavy metal transport) with ecosystem-level applications (precision irrigation, contaminant phytoremediation). Recent publications emphasize genome sequencing, stress tolerance modeling, and nutraceutical food development. ISHS Medal for SapFlow Workshop organization (2011) Giovanni Spitali Foundation Award for PhD dissertation (1998) Collaborations: Extensive international collaborations with institutions like Beijing Forestry University, Comenius University, and Purdue University. Currently supervises projects in plant phenotyping, omics technologies, and sustainable crop management.

• Plant Physiology
• Molecular Plant Stress Responses
• Nutraceuticals in Plants
• +۳ مورد دیگر

Dr. Andre Kahles is a Lecturer in the Department of Computer Science at ETH Zürich, specializing in biomedical informatics. His research focuses on computational methods for analyzing large-scale genomic and transcriptomic data, with applications in cancer genomics, metagenomics, and precision medicine. He has contributed to the development of tools such as SplAdder for alternative splicing analysis, MetaGraph for petascale genomic data exploration, and SECEDO for subclone detection in cancer genomes. His work bridges algorithmic innovation with biological insights, addressing challenges in single-cell analysis, genome graph alignment, and multi-omics integration. Key research themes include: Developing scalable algorithms for processing nanopore sequencing and metagenomic data Characterizing somatic mutations and non-coding drivers in cancer genomes Advancing genome graph-based alignment and annotation methods Integrating multi-omics data for clinical decision-making and tumor profiling His publications span topics like RNA-seq analysis, chromothripsis in cancers, and global urban microbiome tracking through the MetaSUB consortium. Kahles has collaborated on landmark projects including the Pan-Cancer Analysis of Whole Genomes (PCAWG) and the Tumor Profiler Study.

• Bioinformatics
• Genomics
• Cancer Genomics
• +۷ مورد دیگر

Gary M. Shaw is the Rosemarie Hess Professor and Professor (Research) at Stanford University , with courtesy appointments in the Department of Epidemiology and Population Health and Department of Obstetrics & Gynecology - Maternal Fetal Medicine . He serves as Co-PI of the March of Dimes Prematurity Research Center at Stanford and PI of the California Center for Finding Causes and Preventives of Birth Defects . His research focuses on the Epidemiology of birth defects Gene-environment interactions in perinatal outcomes Nutritional factors in reproductive health . He has developed machine learning approaches for precision parenteral nutrition and predictive models for preterm birth, while investigating persistent metabolomic signatures following hypertensive pregnancy disorders. Shaw's recent work explores Climate change impacts on reproductive health Maternal-fetal immune interactions Epigenetic mechanisms in perinatal disease with applications of multiomics to neonatal intensive care units. As a member of Bio-X and the Maternal & Child Health Research Institute , he contributes to translational research networks while serving as Associate Editor for Birth Defects Research and American Journal of Medical Genetics . He supervises Med Scholar Project student Richard Liang Doctoral co-advisor for Saskia Comess and Richard Liang Master's advisor for Lenae Joe while leading the Division of Neonatology as Associate Chair for Clinical Research (2012-2025). His laboratory work integrates Metabolomic profiling Proteomic analysis Computational modeling Machine learning for biomedical data to advance neonatal care through precision medicine approaches.

• Epidemiology of Birth Defects
• Gene-Environment Interactions in Perinatal Health
• Nutrition and Reproductive Outcomes
• +۴ مورد دیگر

Caroline Samer is an Associate Professor at the University of Geneva (UNIGE) Faculty of Medicine and serves as the Head of the Division of Clinical Pharmacology and Toxicology at the Hôpitaux Universitaires de Genève (HUG) . She also acts as the Delegate to the Dean's Office for Data Issues since July 2023. Medical Degree (2001), PhD in Pharmacogenomics, Postdoctoral Fellowship in Molecular Pharmacology (Sydney) President of the Swiss Society for Clinical Pharmacology and Toxicology (SSPTC) and Swiss Society of Pharmacology and Toxicology (SSPT) Vice-President of Swissethics and the Geneva Research Ethics Committee (CCER) Her research focuses on personalizing drug therapy through pharmacogenomics and precision medicine , emphasizing gene-environment-disease interactions and omic technologies . Key themes include drug interactions , pharmacokinetic modeling , and therapeutic information . Recent publications highlight her work in pharmacogenomics , drug safety , and clinical pharmacology , with a focus on opioids , antiaggregants , and drug metabolism . Her collaborations span oncopediatrics , internal medicine , medical informatics , and pharmaceutical sciences . She leads the Samer-Daali Research Group , which integrates in vitro , in vivo , and in silico models to advance personalized therapy . Her work is supported by institutional affiliations with the Faculty Center of Translational Investigation in Biomarkers and CIOMS .

• Pharmacogenomics
• Precision Medicine
• Clinical Pharmacology
• +۳ مورد دیگر

Professor Nick Paul is a marine scientist at the University of the Sunshine Coast (UniSC), leading applied research in seaweed and algae for sustainable product development. He holds a PhD and BSc (Hons) from UNSW and a Graduate Certificate in Tertiary Education Management from the University of Melbourne. His work focuses on seaweed aquaculture innovations, including waste-to-resource biotechnology, functional foods, and environmental remediation. He leads international projects funded by organizations like ACIAR, CSIRO, and Advance Queensland. Research interests include seaweed-based solutions for livestock health, wastewater treatment, and sustainable aquaculture expansion near the Great Barrier Reef. He has pioneered commercial land-based seaweed farming and developed intellectual property in this field. Awards include the 2015 UNAA World Environment Day Award for Sustainable Water Management and the 2015 Queensland Water Innovation Forum Best Paper. He serves on the Asian Fisheries Society Council and Fiji’s National Seaweed Taskforce. Key publications span seaweed cultivation methods, marine genomics, and socio-economic impacts of aquaculture in the Pacific. Grants total over A$3.7 million for projects like diversifying Pacific Island seaweed industries and improving Indonesian seaweed production.

• Marine Science
• Seaweed Aquaculture
• Functional Foods
• +۵ مورد دیگر

Dr. Andrew Bassett serves as Head of the Cellular and Gene Editing Research group at the Wellcome Sanger Institute, where he develops cutting-edge genome engineering techniques using human pluripotent stem cells to investigate neurodegenerative diseases including Alzheimer's and Parkinson's. His work focuses on scaling genetic screening approaches and improving CRISPR specificity for modeling complex disease mechanisms. His academic training includes: PhD at the MRC Laboratory of Molecular Biology (MRC-LMB) with Andrew Travers on chromatin remodelling in heterochromatin formation Postdoctoral research with David Baulcombe at the University of Cambridge studying small RNA roles in chromatin modification Additional postdoctoral work with Chris Ponting at the MRC Functional Genomics Unit (MRC-FGU) in Oxford, where he pioneered CRISPR applications in Drosophila Bassett's research program centers on developing advanced genome engineering methodologies for precise modulation of gene expression networks during development and neurodegeneration. His group specializes in creating complex editing events (SNPs, paired knockouts, enhancer perturbations) within iPSC-derived models, with particular emphasis on epigenetic regulation and transcriptional control. Current projects integrate single-cell 'omics and phenotypic assays to decode genetic causes of neurodegenerative disorders through the OpenTargets consortium. Analysis of his 15 most recent publications reveals dominant trends in CRISPR technology development (35%), neurodegenerative disease modeling (30%), and single-cell functional genomics (25%). His work consistently bridges methodological innovation with disease mechanism studies, increasingly incorporating multi-omics approaches and expanding into cancer immunology and infectious disease applications since 2022. As group leader, Bassett mentors postdoctoral researchers and PhD students while securing major funding for genome engineering initiatives. His team operates within the Sanger Institute's Cellular Operations division and maintains critical partnerships with the OpenTargets consortium for therapeutic target validation. The laboratory specializes in high-throughput screening platforms using iPSC-derived neural and microglial models, with recent methodological advances including scSNV-seq and ONE-STEP tagging systems that significantly enhance precision genome editing capabilities.

• Genome Engineering
• Neurodegenerative Diseases
• Stem Cell Research
• +۵ مورد دیگر