جست‌وجوی استاد و پژوهشگر

Vadim Backmanمشاهده پروفایل

استاد

• Physical Genomics
• Chromatin Engineering
• Nanotechnology
• +۵ مورد دیگر

Dr. Vadim Backman is the Sachs Family Professor of Biomedical Engineering and Medicine at Northwestern University's McCormick School of Engineering and Applied Sciences and Feinberg School of Medicine. He holds additional roles as Professor of Medicine (Hematology/Oncology) and Biochemistry and Molecular Genetics, Associate Director of Research Technology and Infrastructure at the Robert H. Lurie Comprehensive Cancer Center, and Director of the Center for Physical Genomics and Engineering. He earned his Ph.D. in Medical Engineering from Harvard-MIT and M.S./B.S. in Physics from St. Petersburg Polytechnic Institute. His research focuses on physical and biological science intersections, developing nanoscale imaging and computational technologies to study chromatin dynamics and their role in disease. Key areas include cancer diagnostics/therapeutics, chromatin engineering, and genome nanoimaging. Dr. Backman has published over 230 papers, holds 20+ patents, and leads large-scale projects like NCI Bioengineering Research Partnerships. Education: Ph.D. (Harvard-MIT), M.S. (MIT), M.S./B.S. (St. Petersburg Polytechnic Institute) Affiliations: PhD Programs in Applied Physics and Interdisciplinary Biological Sciences Research emphasizes chromatin's role in disease, with clinical translation for diagnostics and therapy. His lab develops technologies like nano-CHIA and ChromSTEM, advancing understanding of genomic organization and epigenetic regulation. Awards include the Cozzarelli Prize and MIT Technology Review's Top 100 Innovators. Awards: Cozzarelli Prize (2017), AIMBE Fellowship (2009), NSF CAREER Award (2003) Grants and collaborations include managing multi-investigator projects and co-founding biotech companies. Courses taught: BME 302 (Quantitative Systems Physiology), BME 429 (Advanced Physical and Applied Optics).

ZHANG Yangمشاهده پروفایل

استاد

• Computational Biology
• Bioinformatics
• Algorithms
• +۶ مورد دیگر

Dr. Yang Zhang is a Professor at the National University of Singapore (NUS), holding appointments in the Department of Computer Science (School of Computing) and the Department of Biochemistry (Yong Loo Lin School of Medicine). He also leads the Zhang Lab, which focuses on AI-driven computational methods for protein structure prediction and design. Previously, he was a Professor at the University of Michigan. His research integrates artificial intelligence, deep learning, and physics-based models to address challenges in computational biology. Affiliations: School of Computing; Yong Loo Lin School of Medicine; Cancer Science Institute of Singapore Key Roles: Principal Investigator of Zhang Lab; Developer of I-TASSER algorithm Research interests span AI-driven protein design, deep learning for RNA structure prediction, and drug discovery. Projects include the EvoDesign server for protein interaction design and TripletRes for coevolution-based contact prediction. Major contributions include the I-TASSER algorithm, ranked top in CASP experiments for protein structure prediction. Awards: Alfred P. Sloan Award, NSF CAREER Award, and seven-time Highly Cited Researcher (2015–2021).

Hanadi Sleimanمشاهده پروفایل

استاد

• Chemical Biology
• Materials Chemistry
• Nanotechnology
• +۳ مورد دیگر

Professor Hanadi Sleiman is a renowned academic in the Department of Chemistry at McGill University, specializing in DNA-based nanomaterials and their applications in drug delivery and supramolecular chemistry. She holds leadership roles, including Director of the NSERC CREATE training program in Nucleic Acids and President of the International DNA Nanotechnology Society (ISNSCE). Her research focuses on engineering DNA nanostructures for targeted therapies, such as cancer treatments, and advancing materials chemistry through DNA-functionalized systems. Education: Ph.D. in Chemistry, Stanford University (1990) Postdoctoral Fellow, University of Louis Pasteur (1993) Research Interests: Professor Sleiman’s work combines synthetic chemistry with DNA self-assembly to create programmable materials. Her lab designs DNA cages for drug encapsulation, explores DNA-minimal approaches to scalable materials, and integrates DNA with nanoparticles, polymers, and metals for biomedical applications. Key areas include cancer therapy, biosensors, and enzyme mimics. Awards & Honors: Fellow of the Royal Society of Canada (2017) Killam Research Fellowship (2018) R. U. Lemieux Award in Organic Chemistry (2018) William Dawson Scholar Award (2004–2012) Grants & Collaborations: She directs the NSERC CREATE program and collaborates with institutions like the Quebec Centre for Advanced Materials (QCAM) and the McGill Centre for Structural Biology (CRBS). Her training initiatives emphasize nucleic acid therapeutics and diagnostics. Labs & Teams: Her Sleiman Group at McGill develops innovative DNA architectures in the Otto Maass laboratory, with a focus on translational research for clinical applications.

Pillai Ramesh Shanmughomمشاهده پروفایل

استاد

• Epigenetics
• RNA modifications
• miRNAs
• +۵ مورد دیگر

Ramesh Shanmughom Pillai is a Full Professor at the Department of Molecular Biology, University of Geneva, Switzerland. He holds additional roles as a Visiting Professor at the University of Kumamoto, Japan, and has been a Group Leader at EMBL Grenoble and a postdoctoral fellow at the Friedrich Miescher Institute. His research focuses on RNA modifications, epigenetics, and piRNA pathways in germline biology. Pillai has received prestigious awards including the ERC Consolidator Grant and The RNA Society Scaringe Award. Education: BSc Botany (University of Kerala, India) MSc Biotechnology (IIT Roorkee, India) PhD in Cell Biology (University of Bern, Switzerland) Research Interests: Pillai’s work centers on RNA biology, particularly the role of RNA modifications (e.g., m6A, m6Am) in development and fertility. He investigates piRNA biogenesis, transposon silencing, and the molecular mechanisms of RNA-protein interactions. His studies bridge biochemistry, genetics, and structural biology to elucidate how RNA molecules regulate critical biological processes. Teaching & Service: At the University of Geneva, he teaches Molecular Biology courses (BSc/MSc levels) and advises 5 PhD students and 4 postdocs. He chairs the ERC Consolidator Grant Review Panel and organizes major conferences like the PIWI/piRNAs Meeting and Swiss RNA Workshop. Pillai also serves on editorial boards for Nucleic Acids Research and RNA . Awards: ERC Consolidator Grant (2015) Best PhD Thesis Award (2003) RNA Society Scaringe Award (2005) Grants & Labs: Funded by ERC Starting and Consolidator Grants, his lab explores RNA modification networks in germ cells. Former trainees include Professors Simon Conn (Flinders University) and Hao Wu (CAS, China).

Istvan Albertمشاهده پروفایل

استاد پژوهشی

• Bioinformatics
• Genomics
• Computational Biology
• +۵ مورد دیگر

Istvan Albert is a Research Professor of Bioinformatics at Pennsylvania State University , affiliated with the Department of Biochemistry and Molecular Biology . He leads the Bioinformatics Consulting Center and teaches BMMB 852: Applied Bioinformatics . Research Interests: Specializing in bioinformatics, large-scale biological data analysis, microarray and sequence analysis, scientific programming, algorithm development, and database-driven web development. His work spans gene ontology visualization , RNA-Seq analysis , and coronavirus research . Software Development: Created GeneScape for gene function visualization and bio for bioinformatics workflows. Maintains the Biostar Handbook series and the Biostars Q&A Forum , a leading bioinformatics resource.

Helma Wennemersمشاهده پروفایل

استاد

• Organic Chemistry
• Chemical Biology
• Peptide Chemistry
• +۵ مورد دیگر

Prof. Dr. Helma Wennemers serves as a Full Professor at ETH Zurich's Department of Chemistry and Applied Biosciences, leading the Laboratory for Organic Chemistry. Her research group operates from HCI H 313 at Vladimir Prelog Way 1-5/10 in Zurich, Switzerland, with active teaching responsibilities including Organic Chemistry I and Chemical Biology - Peptides for the Fall 2025 semester. Her research program centers on the intersection of organic chemistry and chemical biology , with particular emphasis on collagen triple helix engineering , peptide-catalyzed asymmetric synthesis , and development of chemical tools for tissue remodeling diagnostics . Key focus areas include designing hyperstable collagen heterotrimers for fibrosis monitoring, creating fluorophore-based probes for collagen cross-linking visualization, and pioneering organocatalytic methodologies for complex heterocycle synthesis. Her group actively explores how hydrophobic modifications and proline derivatives influence collagen stability and cellular uptake mechanisms. Analysis of her 15 most recent publications (2024-2025) reveals three dominant research trajectories: (1) collagen structural engineering for biomedical applications, (2) innovative peptide/organocatalysis enabling stereoselective transformations, and (3) chemical probe development targeting tissue remodeling processes. These works consistently integrate synthetic chemistry with biological validation, demonstrating translational potential in fibrosis diagnostics and regenerative medicine. While specific grant details aren't provided in available sources, her research program clearly supports advanced laboratory infrastructure including peptide synthesis facilities and photochemical reaction systems like the ETHos photoreactor. Her group maintains strong industry and clinical collaborations evident in applications targeting liver cancer cells and prostate cancer diagnostics. The Laboratory for Organic Chemistry functions as an interdisciplinary hub where synthetic organic chemists collaborate with biologists to develop collagen-based diagnostic platforms and catalytic systems. Current projects focus on lysyl oxidase-responsive probes for real-time tissue monitoring and engineered peptide catalysts for sustainable chemical synthesis under environmentally relevant conditions.

Ralph Bockمشاهده پروفایل

استاد

• Plant Molecular Biology
• Chloroplast Biology
• Organelle Biotechnology
• +۷ مورد دیگر

Prof. Dr. Ralph Bock serves as Director of Department 3: Organelle Biology, Biotechnology and Molecular Ecophysiology at the Max Planck Institute of Molecular Plant Physiology in Potsdam, Germany, where he also leads the Organelle Biology and Biotechnology research group. Previously, he held positions as C4 Professor for Plant Biochemistry and Biotechnology at the University of Münster (2001-2004) and Group Leader at the Institute of Biology III, University of Freiburg (1996-2001). His academic credentials include: Habilitation: University of Freiburg, 1999 Doctorate: University of Freiburg, 1996 Diploma: University of Halle, 1993 Prof. Bock's research focuses on plant molecular biology with particular emphasis on chloroplast biology, organelle biotechnology, and molecular ecophysiology. His work spans genetic engineering of plastids, photosynthesis research, plant biotechnology applications, and understanding organelle-nucleus communication. He has made significant contributions to developing chloroplast transformation systems and applying them to molecular farming, metabolic engineering, and understanding fundamental processes in plant cell biology. His research has important implications for sustainable agriculture, bioenergy, and pharmaceutical production, particularly through the development of plant-based systems for producing vaccines and therapeutic proteins. Analysis of Prof. Bock's recent publications (2023-2025) reveals a strong focus on chloroplast biology, genetic engineering, and molecular farming applications. His work spans fundamental research on organelle genetics, photosynthesis, and stress responses, as well as applied research on using plant and algal systems for biopharmaceutical production. A notable trend is the increasing use of advanced genetic engineering techniques, including CRISPR-based approaches, to manipulate organelle genomes. His research also shows growing interest in algal systems as alternative expression platforms for molecular farming, particularly red algae like Porphyridium for producing viral antigens and glycoproteins.

Adam Caparcoمشاهده پروفایل

استادیار

• Agricultural Biotechnology
• Environmental Biotechnology
• Enzyme Immobilization
• +۶ مورد دیگر

Adam Caparco is the DiPietro Assistant Professor of Chemical Engineering at Northeastern University, with a 25% joint appointment in the Department of Chemistry and Chemical Biology. He leads the Caparco Research Group, focusing on agricultural and environmental biotechnology, enzyme immobilization, and protein assemblies. His work integrates plant virology, nanotechnology, and molecular engineering to address sustainability challenges in agriculture and environmental remediation. He is a member of the Institute for Plant-Human Interface and holds affiliations with Northeastern’s College of Engineering and School of Arts and Sciences. Education: B.S. in Chemical and Biomolecular Engineering from UCLA (2015), Ph.D. from Georgia Tech (2020) under Julie Champion and Andreas Bommarius, followed by a USDA NIFA Postdoctoral Fellowship at UC San Diego under Nicole Steinmetz. His research spans plant immunoengineering, biomanufacturing in plants, and protein-based nanomaterials for bioremediation. Research Interests Plant excretion pathways for pathogen defense and environmental remediation Design of immobilized enzymes for green chemical synthesis Plant virus nanoparticles for nucleic acid delivery and immunity modulation Multifunctional protein engineering for sustainable agriculture Recent articles highlight advancements in plant virus-based delivery systems, enzyme immobilization strategies, and nano-enabled precision agriculture. Awards include the USDA NIFA Postdoctoral Fellowship. Caparco advises graduate and undergraduate researchers, including Julia Hilgemberg Merlin (PhD ChE), Olha Bereziuk (PhD CCB), and Paul Carter (PhD ChE). He collaborates widely and seeks to expand interdisciplinary research in plant biotechnology. Labs/Teams: Caparco Research Group (EXP 420 lab, EXP 530B office) and the Institute for Plant-Human Interface.

Qin Liمشاهده پروفایل

استادیار

• RNA Editing
• Immunology
• Genetics
• +۳ مورد دیگر

Dr. Qin Li is an Assistant Professor of Genetics at the University of Pennsylvania Perelman School of Medicine, affiliated with the Penn Institute for Immunology & Immune Health (I3H), the Penn Institute for RNA Innovation, and the Penn Center for Genomic Integrity. He earned his BS and PhD in Biological Science and Biochemistry & Molecular Biology from Peking University, followed by postdoctoral training at Stanford University. Education : BS (Peking University, 2009), PhD (Peking University, 2014) Dr. Li’s research focuses on the ADAR1-dsRNA-MDA5 axis, exploring how RNA editing mediates self/non-self discrimination in the immune system. His work connects RNA editing quantitative trait loci (edQTLs) to inflammatory disease heritability and develops computational/experimental tools for RNA editing and sensing. Recent publications highlight his contributions to understanding RNA editing’s role in autoimmune diseases, CRISPR-based regulatory principles, and novel RNA ligand engineering. He mentors PhD and Master’s students in Bioengineering, Cell and Molecular Biology, and related programs.

Jason Micklefieldمشاهده پروفایل

استاد

• Biosynthesis
• Biocatalysis
• Antimicrobial Resistance (AMR)
• +۳ مورد دیگر

Jason Micklefield is a Professor of Chemical Biology at the University of Manchester's School of Chemistry and Manchester Institute of Biotechnology. His research focuses on sustainable bio-inspired molecular synthesis, integrating organic chemistry, enzymology, and molecular microbiology. He holds an honorary Visiting Professorship at East China University of Science and Technology. Micklefield earned his PhD in Chemistry from the University of Cambridge in 1993 and completed postdoctoral work at the University of Washington before joining Manchester in 1998. His lab specializes in biosynthesis pathway engineering, biocatalysis, and nucleic acid chemistry. Education: PhD in Chemistry (1993), University of Cambridge NATO Postdoctoral Fellowship, University of Washington, USA (1993–1995) Lecturer in Organic Chemistry, Birkbeck College, University of London (1995–1998) Research Themes: Biosynthesis of novel antibiotics to combat AMR, including pathway engineering for agrochemicals and drug discovery. Biocatalysis and integrated catalysis for sustainable synthesis of pharmaceuticals, focusing on amide ligases and halogenases. Nucleic acid therapeutics and riboswitch engineering for synthetic genetic control. Key Achievements: Discovered CfaL ligases enabling amide synthesis without protecting groups. Engineered vitamin K-dependent carboxylases for novel antibiotic pathways. Developed orthogonal riboswitches for synthetic biology applications. Awards: RSC Bader Award (2019) NPR Lecture Award Lab & Collaborations: The interdisciplinary Micklefield Lab includes chemists, biochemists, and bioinformaticians. Projects include MESNA (modified nucleic acid synthesis) and collaborations on sustainable chemical manufacturing.

• Materials Science
• Nanotechnology
• Photochemistry
• +۶ مورد دیگر

Elina Vuorimaa-Laukkanen is a University Lecturer at Tampere University's Faculty of Engineering and Natural Sciences, Department of Materials Science and Environmental Engineering, and a Docent in Pharmaceutical Nanotechnology at the University of Helsinki's Faculty of Pharmacy. She leads the research team Supramolecular Chemistry of Bio- and Nanomaterials , focusing on light-driven studies of biological processes, solid-phase behavior, and drug release activation. Her work spans multidisciplinary collaboration with chemists, pharmacists, biologists, and physicists. Education : Doctor of Philosophy (Technology), Tampere University, 1994 Licentiate of Philosophy (Chemistry), University of Helsinki, 1993 Research Interests : Her expertise includes Photochemistry and Nanotechnology of self-assembling materials (phospholipids, polymers, proteins, oligo/polynucleotides), Time-resolved Spectroscopy , Fluorescence Lifetime Microscopy , and Langmuir-Blodgett Films . She develops methods to track drug nanocarriers interacting with living cells and investigates Extracellular Vesicles for theranostic platforms. Recent Publications highlight advancements in Chitosan-hyaluronate polyplexes for oligonucleotide delivery, Fluorescence Anisotropy for nanocarrier analysis, and Self-assembly of copoly(2-oxazoline)s for drug encapsulation. Collaborations : She works within Tampere University's Chemistry & Advanced Materials Research Cluster , PREIN Photonics Flagship, GeneCellNano, and the EVE Extracellular Vesicle Ecosystem projects. Teaching : Responsible for Physical Chemistry and Lab Safety courses in the chemistry curriculum.

Helmut H. Streyمشاهده پروفایل

دانشیار

• Biomedical Engineering
• Biophysics
• Microfluidics
• +۶ مورد دیگر

Helmut H. Strey is an Associate Professor in the Department of Biomedical Engineering at Stony Brook University. His research focuses on micro- and nanotechnologies for quantitative biology , including single-cell analysis, cancer metabolism modeling, and functional MRI data analysis. He holds academic appointments since 2008 and has pioneered technologies like tumor-on-a-chip and optical decoders for translation stages. Education: PhD in Biophysics (Technical University München, 1993), postdoctoral training at NIH (1994-1998). Awards include the NSF CAREER Award (2000-2005), Dillon Medal (2003), and Weston Visiting Professorship (2020). Research interests span cell-to-cell variability , Warburg effect in cancer , and Bayesian analysis of time-series data . His lab develops tools for 3D tumor microenvironments, MRI-compatible drug delivery systems, and biomimetic neural circuit models. Teaching includes advanced numerical methods in biomedical engineering, quantitative biology, and biomolecular analysis. Active in open hardware projects, including microfluidics controllers and IoT devices for health monitoring.

David Ackerleyمشاهده پروفایل

استاد

• Enzymes
• Synthetic biology
• Microbiology
• +۴ مورد دیگر

Professor David Ackerley (Victoria University of Wellington) is a leading microbiologist and enzyme engineer specializing in directed evolution of bacterial enzymes for biotechnological applications. As Biotechnology Programme Director since 2006, he lectures in foundational courses like BTEC101 and BTEC201. Academic rank: Professor of Biotechnology Institutional affiliation: Victoria University of Wellington Research focus areas: Microbial Biotechnology, Drug Discovery, Synthetic Biology His research employs Darwinian evolutionary principles to engineer enzymes with enhanced activities, particularly targeting non-ribosomal peptide synthetases and nitroreductases for antibiotic development and cancer therapy. Recent work explores metagenomic domain substitution in pyoverdine biosynthesis and Purpuramine R from marine sponges. Key publications demonstrate innovations in metagenomic library construction , CRISPR screening for regeneration genes, and structural characterization of engineered enzymes. His team has developed NTR 2.0 , a high-efficacy nitroreductase for targeted cell ablation. Current research projects include: Clean solutions from dirty genes: Plastic-degrading enzyme discovery Engineering enzymes for CAR T-cell-chemotherapy synergy Repurposing niclosamide against Gram-negative superbugs Grants from the Health Research Council of New Zealand, Royal Society of New Zealand, and Cancer Society of NZ support his work. Collaborations span biomedical research, synthetic biology, and environmental applications.

• Genome Integrity
• Structural Molecular Biology
• CRISPR-Cas Systems
• +۳ مورد دیگر

Professor Guillermo Montoya is a Research Director and Group Leader at the Protein Structure & Function Program of the Novo Nordisk Foundation Center for Protein Research (CPR), University of Copenhagen, Denmark. His work focuses on unraveling cellular mechanisms at the atomic level through advanced methodologies including X-ray crystallography and cryo-electron microscopy. PhD in Chemistry, University of Zaragoza (1989–1993) MSc in Biochemistry, University of the Basque Country (1984–1989) Montoya's research spans Structural Molecular Biology and Genome Integrity , with specific emphasis on: Activation mechanisms of oligomeric kinases CRISPR-Cas12a conformational dynamics Macromolecular complexes in telomere maintenance His publications reveal significant contributions to CRISPR-Cas systems , kinase activation , and DNA/RNA degradation mechanisms . Scientific Awards: EMBO Member (2018) Spanish National Prize in Biomedicine (2009) Multiple Fellowships (EMBO, Marie Curie, FEBS, Marie Curie) Montoya's group integrates structural biology with cell biology to address fundamental questions in genome stability and biomedical applications. His work has been cited over 188 times for studies on CRISPR-Cas endonucleases and has attracted attention from 41 patents.

• Peptide self-assembly
• Amyloid structures
• HIV transmission mechanisms
• +۵ مورد دیگر

Bradley Nilsson is a Professor of Chemistry at the University of Rochester, Department of Chemistry. He leads the Nilsson Group, focusing on peptide self-assembly, amyloid structures, and their applications in biomedicine and materials science. His work bridges organic, biological, and materials chemistry, with notable contributions to amyloid-inspired hydrogels and HIV transmission mechanisms. He received the 2016 Goergen Award for Excellence in Teaching and the 2012 NSF CAREER Award. Education: PhD in Organic Chemistry (2003, University of Wisconsin-Madison), postdoctoral research at UC Irvine. He joined Rochester in 2006. Research interests include molecular recognition in amyloid peptides, SEVI fibrils' role in HIV transmission, and hydrogel development for tissue engineering. His lab has pioneered studies on stimulus-responsive self-assembly and co-assembly of peptides. Key achievements include the reductive trigger for peptide hydrogelation (JACS 2010), and NIH-funded work on anti-HIV microbicides. Current projects explore amyloid-β oligomer toxicity, SEVI mechanisms, and functional biomaterials from simple amino acid derivatives. Lab members include graduate students Elena Quigley, Melissa Jagrosse, Francine Yanchik, Hannah Distaffen, and Chris Jones. The lab collaborates on interdisciplinary projects funded through NIH and NSF grants.