ZHANG Yang

Dr. Yang Zhang is a Professor at the National University of Singapore (NUS), holding appointments in the Department of Computer Science (School of Computing) and the Department of Biochemistry (Yong Loo Lin School of Medicine). He also leads the Zhang Lab, which focuses on AI-driven computational methods for protein structure prediction and design. Previously, he was a Professor at the University of Michigan. His research integrates artificial intelligence, deep learning, and physics-based models to address challenges in computational biology.

• Affiliations: School of Computing; Yong Loo Lin School of Medicine; Cancer Science Institute of Singapore
• Key Roles: Principal Investigator of Zhang Lab; Developer of I-TASSER algorithm

Research interests span AI-driven protein design, deep learning for RNA structure prediction, and drug discovery. Projects include the EvoDesign server for protein interaction design and TripletRes for coevolution-based contact prediction. Major contributions include the I-TASSER algorithm, ranked top in CASP experiments for protein structure prediction.

Awards: Alfred P. Sloan Award, NSF CAREER Award, and seven-time Highly Cited Researcher (2015–2021).