جست‌وجوی استاد و پژوهشگر

Pillai Ramesh Shanmughomمشاهده پروفایل

استاد

• Epigenetics
• RNA modifications
• miRNAs
• +۵ مورد دیگر

Ramesh Shanmughom Pillai is a Full Professor at the Department of Molecular Biology, University of Geneva, Switzerland. He holds additional roles as a Visiting Professor at the University of Kumamoto, Japan, and has been a Group Leader at EMBL Grenoble and a postdoctoral fellow at the Friedrich Miescher Institute. His research focuses on RNA modifications, epigenetics, and piRNA pathways in germline biology. Pillai has received prestigious awards including the ERC Consolidator Grant and The RNA Society Scaringe Award. Education: BSc Botany (University of Kerala, India) MSc Biotechnology (IIT Roorkee, India) PhD in Cell Biology (University of Bern, Switzerland) Research Interests: Pillai’s work centers on RNA biology, particularly the role of RNA modifications (e.g., m6A, m6Am) in development and fertility. He investigates piRNA biogenesis, transposon silencing, and the molecular mechanisms of RNA-protein interactions. His studies bridge biochemistry, genetics, and structural biology to elucidate how RNA molecules regulate critical biological processes. Teaching & Service: At the University of Geneva, he teaches Molecular Biology courses (BSc/MSc levels) and advises 5 PhD students and 4 postdocs. He chairs the ERC Consolidator Grant Review Panel and organizes major conferences like the PIWI/piRNAs Meeting and Swiss RNA Workshop. Pillai also serves on editorial boards for Nucleic Acids Research and RNA . Awards: ERC Consolidator Grant (2015) Best PhD Thesis Award (2003) RNA Society Scaringe Award (2005) Grants & Labs: Funded by ERC Starting and Consolidator Grants, his lab explores RNA modification networks in germ cells. Former trainees include Professors Simon Conn (Flinders University) and Hao Wu (CAS, China).

Joan Steitzمشاهده پروفایل

استاد

• RNA Processing
• Molecular Biophysics
• Biochemistry
• +۳ مورد دیگر

Joan Steitz is the Sterling Professor of Molecular Biophysics and Biochemistry at Yale University and an Investigator at the Howard Hughes Medical Institute. She holds affiliations with the Yale School of Medicine, the Center for RNA Science and Medicine, and the Yale Cancer Center. Her career includes roles such as Department Chair and leadership in organizations like the American Society for Cell Biology. Education: PhD in Biochemistry from Harvard University (1967); BS from Antioch College (1963). Postdoctoral training at the MRC Laboratory of Molecular Biology, Cambridge. Research focuses on RNA-protein complexes, particularly snRNPs and their roles in RNA processing, viral oncogenesis, and gene expression. Notable discoveries include defining mRNA splicing mechanisms and characterizing noncoding RNAs in herpesviruses. Publications highlight advancements in RNA biology, viral RNA interactions, and stress-induced transcription. Over 300 peer-reviewed articles span molecular biology, virology, and biochemistry. Awards include the Wolf Prize (2021), Lasker Award (2018), and membership in the National Academy of Sciences (1983). Her lab at Yale explores RNA structure-function relationships and viral RNA mechanisms.

Joan A. Steitzمشاهده پروفایل

استاد

• RNA processing
• Noncoding RNA-protein complexes
• Spliceosome assembly
• +۴ مورد دیگر

Dr. Joan A. Steitz is the Sterling Professor of Molecular Biophysics and Biochemistry at Yale University, where she has held positions since 1978. Her research focuses on RNA processing , noncoding RNA-protein complexes , and post-transcriptional gene regulation in eukaryotic cells. She leads the Steitz Laboratory at Yale School of Medicine, investigating mechanisms of pre-mRNA splicing and viral RNA hijacking of host pathways. Key discoveries: snRNP roles in splicing, ENE element stabilization of PAN RNA, and microRNA activation during quiescence. 2002–present: Investigator at Howard Hughes Medical Institute (HHMI). 1996–1999: Chair of Yale's Molecular Biophysics and Biochemistry Department. Research Highlights: Structural insights into MALAT1 triple-helix stabilization, viral snRNA modulation of host miR-27, and nuclear RNA surveillance mechanisms. Her work bridges RNA biophysics , splicing , and viral oncogenesis . Scientific Awards (selected): 2021 Wolf Prize for RNA processing 2018 Lasker-Koshland Special Achievement Award 2015 Connecticut Medal of Science 2005 E.B. Wilson Medal 1992 Member, American Philosophical Society 1986 National Medal of Science Dr. Steitz mentors graduate students like Aarthi Vijayakumar and Chantaka Wongdontri , while training postdoctoral fellows and junior scientists. Her laboratory at Yale explores RNA stabilization, spliceosome assembly, and viral RNA interactions with host machinery, maintaining international collaborations in RNA biology and structural virology .

Joachim Lingnerمشاهده پروفایل

استاد

• Telomeres
• Telomerase
• Long noncoding RNA
• +۶ مورد دیگر

Joachim Lingner is a Full Professor at the Ecole Polytechnique Fédérale de Lausanne (EPFL) since 2009. He previously held positions as Associate Professor (2005–2008), Senior group leader (2002), and Junior group leader (1997–2001) at EPFL and ISREC, Switzerland. He completed his PhD at the Biozentrum of the University of Basel (1989–1992) and postdoctoral work at HHMI, University of Colorado at Boulder (1993–1997). Research Focus: Telomeres, telomerase, genome stability, DNA repair, oxidative stress, RNA biology, and aging. Key Discoveries: Discovery of the catalytic subunit of telomerase (1993–1997), identification of TERRA (telomeric long noncoding RNA), and mechanisms of telomerase regulation. Technologies Developed: Telomeric chromatin analysis protocols to study telomere protein composition and dynamics. Scientific Awards & Honors: ERC Advanced Investigator Grant (2008) EMBO Member (2005) Friedrich Miescher Prize (2002) START-fellowship (1997) Postdoctoral Fellowship SNF (1995) EMBO Long-Term Postdoctoral Fellowship (1993)