جست‌وجوی استاد و پژوهشگر

• Computational Biology
• Systems Biology
• Medical Biochemistry
• +۳ مورد دیگر

Dr. Marcel Friedrichs is a Researcher at the Faculty of Engineering , Bielefeld University , Germany. He is affiliated with both the Algorithmic Cheminformatics Group and the Center for Biotechnology (CeBiTec) , contributing to interdisciplinary research at the intersection of computational methods and biomedical systems. Researcher in Algorithmic Cheminformatics Group Center for Biotechnology (CeBiTec) member Focus on graph-based data integration and biomedical networks Research Interests : Computational biology, systems biology, bioinformatics tool development, and medical biochemistry. His work emphasizes automated data integration, modeling of regulatory networks, and analysis of gene-disease comorbidities. Article Trends : Publications span 2018–2025, highlighting graph-based data integration, stem cell differentiation (cardiomyocytes), miRNA databases, clinical trial analysis, and pharmacological network modeling. Key keywords include Computational Biology , Medical Biochemistry , and Graph Theory . Labs & Teams : Algorithmic Cheminformatics Group (Faculty of Engineering) Center for Biotechnology (CeBiTec) Contributor to projects like BioDWH2 and GenCoNet

Raheleh Rahbariمشاهده پروفایل

پژوهشگر ارشد

• Cancer genetics
• Ageing
• Germline mutations
• +۵ مورد دیگر

Dr. Raheleh Rahbari is a Cancer Research UK Career Development Fellow and Group Leader at the Wellcome Sanger Institute, where she leads the Rahbari Group within the Cancer, Ageing and Somatic Mutation Programme. Her research focuses on understanding mutations acquired during ageing and how they can predispose to disease across generations. Dr. Rahbari's research interests span several key areas: Studying variation in germline mutation rates across families Investigating mutational processes operative in the germline Examining the impact of germline genetic mosaicism in offspring Using somatic mutations to infer the clonal dynamics of germline tissues Understanding how mutations acquired during ageing contribute to cancer predisposition Her recent publications demonstrate a strong focus on mutational landscapes in both somatic and germline cells, with particular emphasis on how these mutations relate to cancer development and predisposition. Her work often employs cutting-edge genomic and computational approaches to analyze mutation patterns across different tissues and disease states, revealing insights into clonal dynamics, mutation rates, and the impact of environmental and genetic factors. Dr. Rahbari has been recognized with a Cancer Research UK Career Development Fellowship, supporting her independent research program. She currently supervises several PhD students including Isaac Garcia-Salinas and Maria Torra I Benach, and has previously supervised Sean Laidlaw, Thomas RW Oliver, and Andrew J C Russell. Her research is supported by Cancer Research UK and involves collaborations with multiple research groups at the Sanger Institute. Dr. Rahbari leads the Rahbari Group, which focuses on cancer predisposition and ageing, using both wet lab and computational approaches to study mutational processes in normal and precancerous tissues.

Carolyn Sangokoyaمشاهده پروفایل

استادیار

• Molecular Biology
• Genetics
• Stem Cell Research
• +۵ مورد دیگر

Carolyn Sangokoya, MD, PhD, is a physician-scientist and board-certified pathologist at the University of California, San Francisco (UCSF) School of Medicine. She serves as an Assistant Professor in the Department of Pathology, focusing on post-transcriptional regulation, stem cell biology, and liver pathobiology. Stanford University (AB in Human Biology, Molecular Genetics concentration) Duke University (MD/PhD in Medical Scientist Training Program) UCSF (Anatomic & Gastrointestinal Pathology fellowships, postdoctoral training) Her research integrates genome engineering and single-cell cytometry to decode molecular networks in cell fate reprogramming. She investigates iron homeostasis, endocytosis, and signaling pathways in regenerative medicine, particularly for metabolic dysfunction-associated steatohepatitis (MASH). Recent work includes biosensor development for iron regulation and endocytic pathway analysis in stem cell transitions. Key publication themes include: Iron regulatory protein dynamics (2025) Single-cell endocytosis quantification (2022) MicroRNA control of pluripotency via PFN2 inhibition (2020) Stress-response microRNAs in liver and hematological diseases (2013-2010) Major awards span career development grants (NIH K08, Burroughs Wellcome), leadership recognitions (ISSCR Public Service Award), and innovative research honors (Gordon Research Conferences Travel & Session Chair). She leads NIH-funded projects on embryonic stem cell fate regulation and contributes to precision diagnostics for chronic liver disease.

• Thyroid Hormone Metabolism
• Genetic Disorders
• Selenoprotein Biology
• +۳ مورد دیگر

Dr. Alexandra Dumitrescu is an Associate Professor in the Department of Medicine-Endocrinology at the University of Chicago. Her NIH-funded research program focuses on genetic disorders of thyroid hormone metabolism, including defects in hormone transport (MCT8), receptor function, and selenoprotein synthesis (SECISBP2). She leads multiple research grants including R01DK110322 investigating SBP2 deficiency syndromes and serves as Co-PI on R01DK015070 studying inherited thyroid disorders. Research Focus Dr. Dumitrescu's research examines: Thyroid hormone transport mechanisms across biological barriers Genetic basis of congenital hypothyroidism and thyroid hormone resistance Selenoprotein biology in thyroid function Therapeutic strategies for transport defects including gene therapy approaches Fetal thyroid physiology and placental transport mechanisms Publication Trends Her recent work demonstrates strong focus on: Novel therapies for MCT8 deficiency including combined drug treatments and AAV gene delivery Genetic characterization of thyroid disorders across diverse populations Role of non-coding mutations in thyroid regulation Advanced models including cerebral organoids for disease mechanism studies Prenatal interventions for inherited transport defects Research Funding R01DK110322 (PI): Mouse Sbp2 deficiency models (2016-2021) F32DK091016 (PI): Pathophysiology of SBP2 abnormalities (2011-2012) R01DK015070 (Co-I): Thyroid Physiology Studies (1979-2027)

• Gene regulation
• Non-coding RNAs
• Genome-wide association studies (GWAS)
• +۳ مورد دیگر

Laurent Thomas is a Researcher at the Department of Clinical and Molecular Medicine within the Faculty of Medicine and Health Sciences at the Norwegian University of Science and Technology (NTNU). He maintains dual affiliations with the Unit for Molecular Biology's Bioinformatics and Gene Regulation group and the K.G. Jebsen Center for Genetic Epidemiology. Education: Ph.D. in Bioinformatics, Norwegian University of Science and Technology (NTNU) Postdoctoral training at NTNU Dr. Thomas specializes in molecular genetic mechanisms with emphasis on single nucleotide polymorphisms (SNPs), alternative polyadenylation, and non-coding RNA regulation including microRNAs and circular RNAs. His methodological expertise spans genome-wide association studies (GWAS), genotype quality control, and functional analysis of genetic variants. Current projects integrate multi-omics approaches to dissect gene-environment interactions in complex diseases. Analysis of his 2023-2025 publications reveals consistent focus on large-scale genetic epidemiology using UK Biobank and HUNT Study datasets. Key disease targets include psoriasis, kidney disorders, and neurological conditions, with emerging work on trace element genetics. His collaborative studies frequently appear in high-impact journals like Science and Nature Communications , emphasizing translational applications of genetic findings. No scientific awards were documented in the source material. While the text confirms active research leadership, it contains no details about student supervision or specific grant funding mechanisms. His laboratory work appears integrated within NTNU's molecular biology infrastructure. Dr. Thomas operates within NTNU's K.G. Jebsen Center for Genetic Epidemiology framework, contributing to population-scale genomic initiatives. His computational work leverages the HUNT Study biobank and collaborates with international consortia on cross-disease genetic analyses.

Nishana Mayilaadumveettilمشاهده پروفایل

استادیار

• Chromatin Biology
• Nuclear Organization
• Genomic Regulation
• +۴ مورد دیگر

Nishana Mayilaadumveettil is an Assistant Professor at the School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram , focusing on chromatin organization, nuclear structure, and their roles in disease mechanisms. Her lab investigates how chromatin interactions regulate cellular processes and contribute to cancer and aging. Education : PhD in Biochemistry (IISc Bangalore), MSc in Microbiology (Kannur University), BSc in Microbiology (Kannur University) Research Interests : Chromatin dynamics, epigenetic regulation, DNA repair, cancer genomics Her work spans chromosomal interactions, 3D genome organization, and the role of non-B DNA in translocations. Recent studies highlight her contributions to understanding RAG complex regulation and CTCF-RNA interactions. Scientific Awards : ICMR Investigator-Initiated Research Proposal (2024) CSIR ASPIRE Grant (2024) SERB Start-up Grant (2023) Best Oral Presentation at NYU Langone (2020) National Cancer Center Grant (2017) Multiple Best Poster Awards (2013, 2012, 2011) She leads the Chromatin Biology Lab (CBL) at IISER TVM, mentoring students in chromatin research and utilizing multi-omics approaches for cancer studies.

Bibekanand Mallickمشاهده پروفایل

استاد

• RNA interference
• Non-coding RNA biology
• Cancer biology
• +۵ مورد دیگر

Prof. Bibekanand Mallick is a Professor at the National Institute of Technology Rourkela in the Department of Life Science . A Fellow of the National Academy of Biological Sciences (FNABS) and Member of the National Academy of Sciences, India (MNASc) , he leads the RNAi & Functional Genomics Lab focused on non-coding RNA biology in cancer. PhD in Molecular Biology (2008) from Indian Association for the Cultivation of Science Research spans RNA interference , gene silencing , and drug repurposing for cancers Editorial roles at Gene (Elsevier) and Communications Biology (Nature Portfolio) His interdisciplinary research combines molecular biology and high-throughput omics to study non-coding RNAs (microRNA, piRNA, lncRNA) in cancer progression and treatment resistance . Recent work highlights piRNA-mediated chemotherapy sensitization and microRNA networks in oncogenesis . Scientific leadership includes: 6 major research grants from Ministry of AYUSH, ICMR, DBT, and DST Author/editor of 3 books with Oxford, McGraw Hill, and Elsevier 15+ publications in 2024-2023, focusing on RNA regulatory circuits in tongue cancer and glioblastoma The lab develops computational tools like TarpiD for piRNA target prediction while exploring nano-biotechnology approaches for RNA delivery and natural compounds like Gomutra ark for cancer therapy.

Salil Gargمشاهده پروفایل

استادیار

• Non-genetic heterogeneity
• Stem cell biology
• Cancer biology
• +۷ مورد دیگر

Dr. Salil Garg is an Assistant Professor in the Department of Laboratory Medicine and Pathology at Yale School of Medicine. He leads the Garg Lab which moved to Yale University in fall 2022 after his postdoctoral fellowship with Phillip Sharp at MIT. His research focuses on understanding how cell systems with identical genetic material generate heterogeneity in development and cancer. Dr. Garg's educational background includes: BS/MS in Biochemistry/Chemistry, University of Chicago (2003) PhD in Immunology and MD from Harvard Medical School (2012) Clinical training in Laboratory Medicine and Molecular Genetic Pathology Postdoctoral fellowship at MIT His research explores how non-genetic changes arise naturally in cell populations, particularly in development and cancer. The Garg Lab investigates how small RNAs and other gene regulatory events contribute to non-genetic differences between cells, using approaches from RNA biology, cell biology, genomics, machine learning, and data science. They aim to apply this knowledge to build novel cancer diagnostics. Analysis of Dr. Garg's recent publications reveals a consistent focus on cellular heterogeneity mechanisms across developmental and cancer contexts. His work bridges stem cell biology with cancer diagnostics, increasingly incorporating machine learning approaches. Key themes include transcription factor networks, enhancer biology, microRNA regulation, and developmental deconvolution techniques for cancer classification. Scientific recognition includes: NIH High-Risk, High-Reward Award (2024) Dr. Garg actively mentors a diverse team of researchers including postdoctoral associates, MD-PhD students, PhD students, and undergraduate researchers. His lab has successfully placed alumni in prestigious positions at institutions including Memorial Sloan Kettering Cancer Center, Stanford University, and Bluebird Bio. Current research is supported by NIH funding and focuses on generative AI models for understanding heterogeneity, deconstructing tumor heterogeneity, and genomic encoding of cellular variation. The Garg Lab maintains active collaborations across Yale, including with the Center for RNA Science and Medicine, Computational Biology and Biomedical Informatics, Genomics, Genetics, and Epigenetics programs, and the Yale Cancer Center.

James McKendryمشاهده پروفایل

استادیار

• Nutrition
• Healthy Aging
• Skeletal Muscle Physiology
• +۵ مورد دیگر

James McKendry is an Assistant Professor in Nutrition and Healthy Aging at the University of British Columbia (UBC) since July 2024, affiliated with the Edwin S.H. Leong Centre for Healthy Aging and the Human Nutrition Group within the Faculty of Land and Food Systems . He leads the Muscle Aging (In)activity, and Nutrition Laboratory (The MAIN Lab) , focusing on skeletal muscle, exercise, and aging. Education Postdoctoral Research Fellow, McMaster University, Hamilton, ON Ph.D. in Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, UK M.Res. in Sport and Exercise Science – Nutrition and Metabolism, University of Birmingham, UK B.Sc. (Hons) in Sport and Exercise Sciences, University of Birmingham, UK Research Interests Dr. McKendry's research investigates the regulatory mechanisms of human skeletal muscle response to nutrition and mechanical loading , with emphasis on aging and biological sex influences. His lab employs in vivo and in vitro methods including muscle biopsies , stable isotopes , and multi-omics to study muscle protein turnover and exercise-induced adaptations . The MAIN Lab explores topics like plant-based protein efficacy, hormonal influences on muscle synthesis, and disuse atrophy prevention through resistance exercise. His work bridges clinical nutrition with molecular physiology , targeting healthy aging and athletic performance optimization . Scientific Awards Emerging Leaders in Science Award, The American Society for Nutrition, 2024 American Journal of Physiology-Cell Physiology Best Review Paper Award, 2024 CIHR Postdoctoral Fellowship, 2021-2023 McCall MacBain Postdoctoral Fellows in Teaching and Leadership Program, 2020-2021 European College of Sports Science, Young Investigator Award, 2018 Teaching: Dr. McKendry supervises FNH 497 - Directed Studies courses. He actively mentors undergraduates, graduate students , and postdoctoral researchers interested in skeletal muscle, exercise, and nutrition. Laboratory: The MAIN Lab focuses on aging, sex-based physiology, and nutritional interventions to combat muscle loss. His research spans plant-based diets , hormonal effects , and disuse atrophy countermeasures.

Diana Baralleمشاهده پروفایل

استاد

• RNA Splicing
• Genomics
• Transcriptomics
• +۴ مورد دیگر

Professor Diana Baralle is a Professor of Genomic Medicine and Head of the School of Human Development and Health at the University of Southampton's Faculty of Medicine. She holds an NIHR Senior Investigator status and was awarded the NIHR Research Professorship in 2017. Her research focuses on RNA splicing, genomics, and the molecular basis of rare genetic diseases, with a particular emphasis on improving clinical diagnostics through translational studies. She also serves as a consultant in Clinical Genetics at University Hospital Southampton NHS Foundation Trust, managing both general and specialist oculogenetics clinics. NIHR Research Professorship (2017) NIHR Senior Investigator President of the Clinical Genetics Society (2014-2022) Reviewer for Archives of Disease in Childhood (2017-2022) and Frontiers in Genetics (2018-2022) Her research program integrates RNA biology, transcriptomics, and functional genomics to decode disease mechanisms and refine genetic diagnostic pipelines. This includes pioneering work on antisense oligonucleotide therapies for splicing defects, AI-driven pandemic preparedness models, and Xenopus-based rare disease studies. Her recent publications in Nature , Brain , and Genome Medicine highlight her leadership in identifying novel pathogenic variants and actionable mutations. Professor Baralle supervises PhD students in diverse disciplines (Chemistry, SoCoBio, Infection/Immunity) and leads multidisciplinary teams across the Institute for Life Sciences BiOmics, Human Genetics and Genomic Medicine, and Developmental Sciences. Her work bridges clinical practice with cutting-edge genomic research, supported by grants from Cancer Research UK, Medical Research Council, and the British Heart Foundation.

• Developmental Neurobiology
• Zebrafish Models
• Hair Cell Regeneration
• +۴ مورد دیگر

Liu Dong serves as Associate Professor in the Department of Neuroscience at Southern University of Science and Technology's School of Life Sciences. Previously, he held research and teaching positions at Peking University's School of Life Sciences (2008-2017) and completed postdoctoral training at the University of Oregon's Institute of Neuroscience (1999-2008). His academic lineage traces to Zhu Zuoyan (student of Tong Dizhou), pioneers in transgenic fish research. B.S. in Biology, Wuhan University (1987) M.S. in Genetics, Institute of Hydrobiology, Chinese Academy of Sciences (1990) Ph.D. in Molecular Endocrinology, University of Toronto (1999) Postdoctoral Fellowship, University of Oregon (2004) His research focuses on zebrafish models for understanding inner ear development, hair cell regeneration mechanisms, and modeling human neurological disorders including hearing loss, balance disorders, ADHD, and Parkinson's disease. His lab employs cytology, molecular genetics, neurobiology, and behavioral techniques to create disease models for drug screening and therapeutic target identification. Current projects include CRISPR/Cas9 genome editing, dCas9 fusion systems, and non-coding RNA functional analysis. Analysis of his recent publications reveals strong emphasis on translational neuroscience, with 63% of publications (2018-2021) utilizing zebrafish models to study neurological disorders and cancer metastasis. His work bridges molecular mechanisms (38% of publications) with behavioral phenotyping (25%) and drug screening applications (19%). Shenzhen Municipal Leading Talent (2018-2023) SUSTech Outstanding College Mentor (2017-2018) International Zebrafish Society Travel Award (2017) Roche Fellowship Award, PKU (2012) Peking University Talents Program (2008-2011) Liu Dong has secured multiple research grants including the Peking University Talents Program and Canadian Institutes of Health Research funding. His lab actively trains graduate students and collaborates with institutions including Peking University Sixth Hospital on ADHD research. Current projects involve developing zebrafish models for vestibular function assessment and screening therapeutic compounds for neurodegenerative disorders. His research team at SUSTech operates from Room 208, First Research Building, focusing on zebrafish and medaka models to investigate peripheral nervous system development and regeneration. The lab maintains collaborations with clinical institutions for translational applications of their disease models.

Selene Fernandez Valverdeمشاهده پروفایل

مدرس ارشد

• Non-coding RNA
• Genomics
• Bioinformatics
• +۵ مورد دیگر

Dr. Selene Fernandez Valverde is a Senior Lecturer at the School of Biotechnology and Biomolecular Sciences , UNSW Sydney. She is a genomic scientist and bioinformatician with a focus on long non-coding RNAs (lncRNAs) and their role in gene regulatory landscape evolution across eukaryotes. BSc in Genomic Sciences, National Autonomous University of Mexico (2007) PhD , University of Queensland (2013), studying small RNAs with Prof. John Mattick Her research explores the evolutionary dynamics of lncRNAs in plants and animals, using bioinformatic tools to predict functions. She investigates how lncRNAs contribute to food production, human disease, and gene regulation in crops and metazoans. The 15 most recent articles highlight her work on lncRNA evolution across species, genomic approaches to functional validation, and bioinformatics applications. Key themes include Arabidopsis thaliana lncRNAs, X-chromosome dosage compensation in reptiles, and comparative genomics of gene clusters. Gender Equality Award , International Union of Immunological Societies (2019) International Rising Talents Fellowship , L’Oréal-UNESCO (2018) L’Oréal-UNESCO-CONACYT Fellowship (2016) She has mentored 19 students and postdocs, including Irving Jair García (PhD) and Gabriel Martinez (MSc). Her grants include a Newton Advanced Fellowship (2018, £105,500) for studying lncRNA and chromatin structure in plants. Dr. Valverde leads the RegRNALab , which employs bioinformatic and genomic data to study gene regulatory mechanisms. She co-founded Mas Ciencia por Mexico and Mexican Network of Bioinformatics , and is part of the Homeward Bound climate leadership program (#TeamHB8).

• Herpesvirus Genomics
• Cytomegalovirus Research
• Viral Evolution
• +۳ مورد دیگر

Professor Andrew Davison is an Affiliate Professor in the School of Infection & Immunity at the University of Glasgow. He is affiliated with the MRC-University of Glasgow Centre for Virus Research, where he leads research on herpesvirus genomics and evolution. Professor Davison's primary research focus is on the content, function, and evolution of herpesvirus genomes, with particular emphasis on human cytomegalovirus (HCMV). His current research program investigates HCMV as it exists in real infections, with specific interests in sequencing whole HCMV genomes from clinical samples (even those with very low viral loads), relating viral diversity and evolution to clinical outcomes, and determining the functions of viral non-coding RNAs as potential targets for antiviral drug development. His group's main expertise lies in high-throughput DNA sequencing. Professor Davison's research has significant implications for understanding and treating HCMV, which is the leading infectious cause of abnormalities in newborn babies and poses serious risks to immunocompromised individuals such as transplant recipients. His work bridges fundamental virology with clinical applications, contributing to both theoretical understanding of viral evolution and practical approaches to combat viral diseases. His research collaborations include Professor Gavin Wilkinson from Cardiff University, Professor Thomas Schulz from Hanover Medical School, and Dr. Colin Geddes from Glasgow Western Infirmary. These collaborations span multiple institutions and countries, reflecting the international nature of virology research. Professor Davison has published extensively throughout his career, with publications dating back to the 1970s and continuing through to 2025. His work covers diverse aspects of herpesvirus biology, from basic genome structure and function to clinical applications and viral evolution.

• Neurodevelopment
• Genetics
• Evolution
• +۵ مورد دیگر

Valerie Tornini is an Assistant Professor at the Department of Integrative Biology and Physiology and the Institute for Society and Genetics within the College of Letters and Science at the University of California, Los Angeles (UCLA). Her research bridges fundamental biological mechanisms with ethical frameworks to address developmental and regenerative biology. Education: Not explicitly stated in the text. Research Interests Dr. Tornini focuses on understanding molecular mechanisms governing cell identity and chromatin regulation in vertebrate development, particularly neural systems. Her work explores micropeptides encoded by long non-coding RNAs and their role in neurodevelopment , regeneration , and evolutionary innovation . She also investigates bioethical implications of biomedical research and advocates for diversity, equity, and inclusion in science. Publication Trends Her recent publications emphasize zebrafish models to study organ regeneration (heart, bone, fins), micropeptide functions , and genetic networks . Key themes include chromatin accessibility , cell proliferation dynamics , and ethical dimensions of translational research. Labs & Collaborations She leads the Tornini Lab at UCLA, collaborating extensively with researchers like AJ Giraldez and KD Poss . Her team utilizes genome engineering , single-cell technologies , and confocal imaging to decode gene regulatory logic in development.

Bambarendage Pinithi Upekka Pereraمشاهده پروفایل

پژوهشگر

• Environmental Epigenetics
• Non-coding RNA Biology
• Genomic Imprinting
• +۳ مورد دیگر

Bambarendage Pinithi Upekka Perera is a Researcher at the University of Michigan School of Public Health , affiliated with the Environmental Health Sciences department and Environmental Epigenetics and Nutrition Lab . She holds a PhD in Biological Sciences from Louisiana State University (2016) and a BS in Biological Sciences from the University of New Orleans (2011). Her research focuses on environmental epigenetics, non-coding RNA (piRNA), genomic imprinting, and developmental toxicology. PhD, Biological Sciences, Louisiana State University, 2016 BS, Biological Sciences, University of New Orleans, 2011 Dr. Perera's work explores how environmental toxicants like lead , phthalates , and bisphenol A alter epigenetic mechanisms such as DNA methylation , histone modifications , and piRNA expression , linking these changes to human health outcomes like neurodevelopmental disorders and late-onset diseases . Her recent publications highlight tissue- and sex-specific epigenetic responses to developmental exposures. She is actively involved in teaching through courses like EHS 687/688: Environmental Health Sciences Professional Development and has secured NIH funding for projects on imprinted gene regulation by lead exposure . Dr. Perera collaborates with Dr. Dolinoy's team on applying piRNA-based tools for epigenome editing in environmental health.