جستجوی استاد راهنمای دانشگاهی

Beate Escherمشاهده پروفایل

استاد

• Environmental Toxicology
• In Vitro Bioassays
• New Approach Methods (NAMs)
• +۱۲ مورد دیگر

Prof. Dr. Beate Escher is Head of the Department of Cell Toxicology at the Helmholtz Centre for Environmental Research (UFZ) in Leipzig, Germany. She holds professorial positions at Eberhard Karls University of Tübingen , is a Privatdozent at ETH Zurich , and is affiliated with the University of Queensland and Griffith University in Australia. Her research program focuses on advancing in vitro bioassays and New Approach Methods (NAMs) for environmental and human health risk assessment of micropollutants. Her research interests lie at the intersection of environmental toxicology , molecular toxicology , and exposure science . She develops and applies bioanalytical tools for water quality assessment, with a focus on pharmaceuticals, pesticides, and transformation products. Her work includes mechanism-based toxicity assessment , toxicokinetic-toxicodynamic (TKTD) modeling , and the development of the CITEPro robotic bioassay platform for high-throughput screening. She integrates omics data , computational modeling , and machine learning to improve chemical hazard characterization. Recent publications highlight trends in chemical mixture toxicity , safe-by-design chemicals , ionic compound assessment , and machine learning applications in toxicology. Her work increasingly leverages data-driven approaches to prioritize contaminants and predict biological effects across species. Scientific Awards: Highly Cited Researcher (Web of Science/Clarivate, Top 0.1%, 2020) Outstanding Achievements in Environmental Science and Technology (ES&T & ACS ENVR, 2023) Advising and Grants: She supervises multiple doctoral students and leads major collaborative projects such as InCeTo, MibiTox, nanoINHALE, and SafePol. She received an Australian Research Council grant (2011–2014) and leads Swiss National Science Foundation-funded initiatives. She was a member of the German Science Council (2017–2024) and serves on the Board of Reviewing Editors of SCIENCE . Labs and Teams: She leads the Cell Toxicology team at UFZ, which includes researchers such as Dr. Luise Henneberger, Dr. Julia Huchthausen, and Dr. Haotian Wang. The team operates the CITEPro platform and contributes to international consortia focused on exposome research and chemical safety.

• Numerical Fourier Analysis
• Wavelet Theory
• Signal Processing
• +۳ مورد دیگر

Gerlind Plonka-Hoch is a Professor of Applied Mathematics and Deputy Director of the Institute for Numerical and Applied Mathematics (NAM) at the University of Göttingen. She leads research in numerical analysis and signal processing, with a focus on mathematical methods for image reconstruction and analysis. Her work bridges theoretical mathematics with practical applications in medical imaging and data science. Professor Plonka-Hoch's research spans several key areas in applied mathematics: Numerical Fourier analysis and fast algorithms Wavelet theory and sparse signal representation Regularization methods and nonlinear diffusion Applications in signal and image processing, particularly medical imaging Phase retrieval and parameter estimation problems Her recent publications demonstrate a strong focus on medical imaging applications, particularly using Optical Coherence Tomography (OCT) data. She has developed innovative approaches combining wavelet analysis, deep learning, and sparse representation techniques for image reconstruction and classification. Her work on ESPIRA (Estimation of Signal Parameters by Iterative Rational Approximation) has provided new methods for reconstructing exponential sums from limited data, with applications across multiple scientific domains. Professor Plonka-Hoch leads an active research group at the University of Göttingen, mentoring several doctoral students including Dr. Yurii Kolomoitsev, M.Sc. Benjamin Kocurov, M.Sc. Anahita Riahi, M.Sc. Yannick Nicola Riebe, and M.Sc. Janina Schmidt. Her working group has produced numerous publications on numerical methods and their applications, with a strong emphasis on both theoretical foundations and practical implementation.

Tamara Talمشاهده پروفایل

استاد

• Developmental Neurotoxicity
• Molecular Toxicology
• Chemical-Microbiome Interactions
• +۴ مورد دیگر

Professor Tamara Tal is a leading researcher in toxicology currently holding dual appointments as Professor of Integrated Systems Toxicology at the University of Leipzig Faculty of Medicine and Group Leader of the Molecular Toxicology Group at the Helmholtz Centre for Environmental Research - UFZ in Leipzig, Germany. Her research program focuses on developing new approach methodologies for neurotoxicity assessment, resolving molecular mechanisms of chemical toxicity, and investigating chemical-microbiome interactions affecting host outcomes. Dr. Tal received her PhD in Toxicology from the University of North Carolina Chapel Hill (2003-2008), followed by postdoctoral training at Oregon State University (2008-2011) and the US Environmental Protection Agency (2011-2015), where she later served as Principal Investigator (2015-2019). Her groundbreaking work has established zebrafish as a powerful model for high-throughput screening of environmental chemicals, particularly for developmental neurotoxicity assessment. Her research interests center on three interconnected areas: developing new approach methods (NAMs) for developmental neurotoxicity, using molecular approaches to resolve mechanisms of chemical-induced adverse outcomes, and investigating how chemical-microbiome interactions affect host toxicity. She has made significant contributions to understanding PFAS toxicity mechanisms, particularly how these 'forever chemicals' affect neurodevelopment through GABA receptor antagonism and microbiome disruption. Analysis of her recent publications (2021-2025) reveals a strong trend toward multi-behavioral phenotyping in zebrafish to identify subtle neurotoxic effects, investigation of chemical-microbiome interactions in toxicity pathways, and development of regulatory-ready testing methodologies. Her work bridges molecular mechanisms with organism-level outcomes, frequently employing the CITEPro high-throughput platform at UFZ for chemical screening. Helmholtz W2 Award (2021-2026) for NEURO-XENO-MICROBIOME project Paper of the Year Award, Society of Toxicology (2020) US EPA Science and Technological Achievement Award (2017) Multiple first-place awards from Society of Toxicology (2015) Dr. Tal leads the MibiTox project investigating the intestinal microbiome's role in pesticide-induced disease pathogenesis and contributes significantly to the PARC work package 5 project developing new neurotoxicity assessment methods for regulatory use. Her laboratory leverages the CITEPro platform for high-throughput sample preparation, automated exposure systems, and effect analysis, enabling comprehensive chemical screening while maintaining biological relevance.

Vanessa Srebnyمشاهده پروفایل

پژوهشگر

• Environmental Toxicology
• Chemical Risk Assessment
• Biodegradable Materials
• +۳ مورد دیگر

Vanessa Srebny is a Researcher in the Department of Cell Toxicology at the Helmholtz Centre for Environmental Research (UFZ), part of the Chemicals in the Environment research unit. She holds a B.Sc. in Biochemistry from the University of Heidelberg (2014–2017) and an M.Sc. in Biotechnology from Lund University. Her work focuses on developing novel hazard indicators (CTE and PTE) for chemical risk assessment under the Partnership for the Assessment of Risks from Chemicals (PARC) initiative. She also contributes to the Helmholtz Platform SynCom, fostering interdisciplinary dialogue between industry, regulators, and researchers. Her research includes a comparative toxicity study of Bisphenol A alternatives and advancing machine learning tools like MLinvitroTox for chemical hazard prioritization. Previous roles include internships at Nestlé Institute of Packaging (developing enzymatic recycling methods) and the Food Packaging Forum Foundation (science communication). She actively participates in international conferences such as SETAC Europe, presenting advancements in New Approach Methodologies (NAMs) and chemical exposome research.