جست‌وجوی استاد و پژوهشگر

• Molecular Biology
• Neuroscience
• Regenerative Medicine
• +۵ مورد دیگر

Quansheng Du is an Associate Professor at the Medical College of Georgia , affiliated with the Department of Neuroscience and Regenerative Medicine and the Department of Neurology . His academic appointments include teaching responsibilities in advanced molecular biology courses such as BIOM 8230 Biology of Proteins in Disease and BIOM 8022 Molecular Cell Biology . Education: Ph.D., Molecular Biology, Wuhan University (1999) MS, Molecular Biology, Wuhan University (1995) Research Interests span molecular mechanisms in neurological diseases, regenerative medicine, and metabolic pathways in cancer cachexia. His work includes studies on genetic disorders (MRKH syndrome), microRNA roles in neuronal survival, purine synthesis inhibition in pulmonary hypertension, and TEAD1 signaling in cardiomyocyte protection. Recent Publications (2021–2024) focus on molecular biology intersections with neuroscience, cardiovascular diseases, and cancer metabolism, with recurring themes in genetic regulation, cellular reprogramming, and metabolic dysregulation.

Martin A. Vinckمشاهده پروفایل

استاد

• Computational Neuroscience
• Systems Neuroscience
• Neural Coding
• +۱۰ مورد دیگر

Prof. Dr. Martin Vinck is a Professor at the Donders Centre for Neuroscience in the Department of Neurophysics , Radboud University. He is also a Research Group Leader at the Ernst Strüngmann Institute for Neuroscience and a faculty member at the International Max Planck Research School for Neural Circuits . Current affiliations: Radboud University, ESI Frankfurt, Max Planck Research School Positions: Professor, Research Group Leader, Review Editor for eLife Research Interests span computational and systems neuroscience, focusing on predictive processing in biological and artificial neural networks. His lab investigates: How distinct excitatory/inhibitory neurons regulate plasticity and flexible information processing Neural ensemble coding via spatio-temporal patterns and spike sequences Self-supervised learning mechanisms using spatial/temporal predictions Gamma oscillations, synchronization, and their role in visual encoding Scientific Contributions include developing algorithms for high-dimensional neural data analysis, co-supervising key studies on interneuron dynamics, and pioneering work on predictive coding in V1. His grants include the ERC Starting Grant (2019) and VIDI Grant (2024) . Lab Members include PhD students Jinke Liu, Jahan Esfandiarii, Athanasia Tzanou and alumni Irene Onorato, Marius Schneider, Ana Clara Silveira Broggini . He actively promotes open science , develops the Spike Toolbox , and reviews for journals like Neuron, eLife, PLoS Computational Biology .

Sean Lawlerمشاهده پروفایل

دانشیار

• Brain Cancer Therapy
• Translational Oncology
• Blood-Brain Barrier
• +۵ مورد دیگر

Sean Lawler, Ph.D. is an Associate Professor of Pathology and Laboratory Medicine at Brown University, leading the Brain Cancer Therapy Lab. He is affiliated with the Brown Cancer Center as co-leader of the CNS Cancer Translational Disease Research Group. Specializes in translational approaches for brain tumor therapy Previous faculty appointments at Harvard, Ohio State, and University of Leeds Focus on glioblastoma and pediatric high-grade glioma Research interests include: Drug delivery across the blood-brain barrier Immunotherapy development for brain cancers Role of cytomegalovirus in glioblastoma progression His lab explores three main areas: blood-brain barrier modulation, immune system activation against brain tumors, and CMV-induced cancer growth mechanisms. Recent publications emphasize glioblastoma immunology, drug delivery innovations, and tumor microenvironment dynamics, particularly through STING activation and peptide-drug conjugates. Dr. Lawler teaches BIOL 1295 - Fundamentals of Cancer Immunotherapy at Brown University.

Henri Tiedgeمشاهده پروفایل

استاد

• RNA Biology
• Neurobiology
• Translational Regulation
• +۵ مورد دیگر

Henri Tiedge, PhD , is a Professor at the Department of Physiology and Pharmacology within SUNY Downstate Medical Center . His research focuses on regulatory brain cytoplasmic (BC) RNAs , particularly their role in translational control mechanisms at neuronal synapses and their implications in neurological disorders and tumor biology . Institutional Affiliation: SUNY Downstate Medical Center (College of Medicine, Physiology and Pharmacology) Academic Rank: Professor Research Domains: RNA Biology, Synaptic Plasticity, Neurodegeneration, Oncology Dr. Tiedge investigates how BC1 and BC200 RNAs regulate local protein synthesis in dendrites through interactions with eukaryotic initiation factors (eIF4A/B) . His work demonstrates that BC RNA dysregulation leads to neuronal hyperexcitability , epileptogenesis , and cognitive dysfunction , with therapeutic applications in neuropsychiatric lupus using RNA decoys. He also explores BC RNA expression in germ cells and tumors , aiming to develop diagnostic/prognostic tools for cancer. Key publications include studies on RNA transport via hnRNP A2 and Purα , autoantibody-induced RNA displacement , and cross-talk between BC RNAs and FMRP in fragile X syndrome. His work has been supported by NIH grants NS046769 and DA026110 .

• Biophysics
• Computational Biology
• Systems Biology
• +۲ مورد دیگر

Mathias Spliid Heltberg is an Assistant Professor at the Biocomplexity section of the Niels Bohr Institute, University of Copenhagen. His research focuses on nonlinear dynamics in biological systems, particularly oscillatory mechanisms in cellular processes and medical informatics applications. Current affiliation: Niels Bohr Institute, University of Copenhagen Research areas: Biocomplexity, Systems Biology, Chronobiology His recent publications span topics like p53 dynamics in DNA damage response, signal transmission in excitable media, and medical informatics applications. Collaborations include institutions in Denmark, USA, and China. The research integrates computational modeling with experimental validation in diverse biological contexts. Key contributions include theoretical frameworks for biological oscillations and practical applications in gestational diabetes intervention and surgical outcome prediction. His work on allelic buffering and potassium ion dynamics highlights cross-disciplinary approaches combining physics and biology.

• Biochemistry
• Rare Diseases
• Alkaptonuria
• +۴ مورد دیگر

Giulia Bernardini is an Associate Professor at the Department of Biotechnology, Chemistry and Pharmacy, University of Siena. She teaches Applied and Clinical Biochemistry in the Pharmacy program and maintains regular office hours at the Polo Scientifico San Miniato. Her research focuses on rare diseases like Alkaptonuria and Lesch-Nyhan Disease , with emphasis on biochemical pathways, proteomics, and in vitro modeling. Email: giulia.bernardini@unisi.it Phone: +39 0577 235792 Webex Virtual Room: Join Here Her recent work explores omics technologies in rare disease research, enzyme inhibition for novel therapeutics, and computational workflows targeting metabolic disorders. Publications highlight collaborations with international consortia like the DevelopAKUre project. Key research areas include: Homogentisic acid pathophysiology in Alkaptonuria Purine salvage pathway defects Induced pluripotent stem cell modeling 4-Hydroxyphenylpyruvate Dioxygenase (HPPD) inhibition Inflammatory/oxidative stress biomarkers Proteomic profiling of rare diseases

R. Michael Burgerمشاهده پروفایل

استاد

• Auditory Neuroscience
• Neural Circuitry
• Synaptic Physiology
• +۳ مورد دیگر

R. Michael Burger is a Professor in the Department of Biological Sciences at Lehigh University and serves as the Associate Dean for Research and Graduate Programs in the College of Arts and Sciences. His research focuses on auditory neuroscience, particularly how the brain processes sensory information through precise neural circuits. Education Ph.D. in Zoology (Neurobiology) from the University of Texas at Austin (2000) B.A. in Psychology and Anthropology from Ithaca College (1993) Dr. Burger's research investigates cellular, synaptic, and systems-level integration in auditory processing, with NIH-funded projects on sound localization and cholinergic modulation. He has edited books on neuromodulatory functions and serves on editorial boards of leading journals. Recent publications highlight his work on dopamine and cholinergic influences in auditory pathways, developmental synaptic plasticity, and computational auditory neuroscience. Grants include NIH R01 and R15 awards. Scientific Awards Fellow, Alexander von Humboldt Foundation Dr. Burger teaches behavioral neuroscience courses and contributes to graduate committee work, otolaryngology research, and grant review panels. He co-developed the HearMyCl app for cochlear implant simulations with Susan Perry and Brook Sawyer.

Russell Carrمشاهده پروفایل

استاد

• Toxicology
• Neurotoxicology
• Environmental Health
• +۳ مورد دیگر

Russell Carr , PhD, is a Professor at Mississippi State University's College of Veterinary Medicine. Holding a PhD in Animal Physiology (MSU, 1994) and MS in Biological Sciences (MSU, 1990), he focuses on neurotoxicology, pesticide mechanisms, and endocannabinoid system interactions. His career spans 30+ years studying organophosphate effects on neurotransmitter systems across developmental stages. Key Research Areas: Organophosphate pesticide neurotoxicity Endocannabinoid system disruption Developmental neurochemical impacts Cross-species enzyme inhibition Recent Publications (2023-2021) reveal trends in nanochannel CBD delivery systems, chlorpyrifos-induced proteomic changes in amygdala, and multi-omics approaches to pesticide-immune interactions. Earlier works establish foundational knowledge on cholinesterase inhibition kinetics and age-dependent toxicity profiles. Notable Contributions: Elucidated mechanisms of endocannabinoid enzyme inhibition by pesticides, demonstrated neurochemical impacts of low-dose exposures, and developed comparative models across species (rodents, fish).

Jeffrey M. Chungمشاهده پروفایل

دانشیار

• Epilepsy
• Neural Signal Processing
• Neurosurgery
• +۴ مورد دیگر

Jeffrey M. Chung, MD, FAAN is an Associate Professor of Neurology at Cedars-Sinai Medical Center. He serves as Director of both the Epilepsy Program and the Neurophysiology Laboratory since 2013. His clinical practice focuses on epilepsy and neurophysiology, with 26 years of experience in neurology and clinical neurophysiology. Northwestern University Medical School (1999) - MD Evanston Hospital (2000) - Internship UCLA (2003) - Residency UCLA (2005) - Fellowship Dr. Chung's research explores epilepsy mechanisms, neural signal processing , multi-modal probabilistic mapping for surgical outcomes, and device-oriented therapies . His recent publications focus on theta phase precession in memory , single-neuron correlates of seizures , and neuroimaging in post-stroke conditions . He leads clinical trials on novel anti-seizure agents and neuromodulation techniques. Circle of Friends – Grateful Patient Donation Honoree (Cedars-Sinai) Southern California Super Doctors (Los Angeles Magazine) Falks Medical Scholar (Arthritis Foundation) Golden Apple Teaching Award (Cedars-Sinai) Dr. Chung directs the Epilepsy Program and Neurophysiology Laboratory at Cedars-Sinai, while also mentoring through journal clubs and clinical teaching. He has received multiple industry grants from companies like Marinus Pharmaceuticals and Vertex Pharmaceuticals for trials on treatment-resistant epilepsy. His work bridges clinical care with neurophysiological research and advanced neural signal processing .

• Molecular Biology
• Biochemistry
• Neurodegenerative Diseases
• +۱۰ مورد دیگر

Dr. Andrey L. Karamyshev is an Associate Professor at the School of Medicine, Texas Tech University Health Sciences Center, in the Department of Cell Biology & Biochemistry. His research focuses on molecular mechanisms of human diseases, particularly neurodegenerative disorders and cancer, through the lens of protein synthesis regulation and quality control. Academic Rank: Associate Professor Research Affiliation: Institute for One Health Innovation Research Interests include: Molecular mechanisms of translational regulation RNA and protein quality control Protein interactions in health and disease Signal Recognition Particle (SRP) dysfunction in neurodegenerative diseases Role of AGO2 in mRNA degradation Co-translational protein folding and targeting Recent Publications highlight his work on the RAPP pathway, SRP interactions in Leishmania, and protein misfolding in Parkinson’s and Alzheimer’s diseases. His studies integrate in vivo and in vitro methodologies, including photo-crosslinking and iPINCH techniques. Scientific Awards & Recognition : Featured in Trends in Biochemical Sciences (2014) Highlighted in Nature Reviews Genetics (2014) Recommended by Faculty of 1000 (F1000Prime) for multiple publications Top 5.0% viewed/downloaded article in Frontiers (2018) Dr. Karamyshev welcomes graduate students to his lab, emphasizing collaboration and innovative research in molecular biology and biomedical sciences. His lab is affiliated with the Institute for One Health Innovation, fostering interdisciplinary approaches to human disease treatment.

Tobias Bonhoefferمشاهده پروفایل

استاد

• Synaptic plasticity
• Learning and memory
• Activity-dependent development
• +۴ مورد دیگر

Prof. Dr. Tobias Bonhoeffer serves as Director and Head of the Department of Synapses – Circuits – Plasticity at the Max Planck Institute for Biological Intelligence in Munich, Germany. His research focuses on synaptic plasticity, learning and memory, and the structural and functional dynamics of the visual system and hippocampus. Institution: Max Planck Institute for Biological Intelligence Department: Synapses – Circuits – Plasticity Academic Rank: Professor Research Interests encompass cellular and systems neurobiology, with specialized investigations into: Synaptic plasticity mechanisms Structural changes in dendritic spines Experience-dependent cortical circuit formation Memory relearning efficiency Functional mapping in visual cortex Neural adaptation in behaving animals Publications demonstrate expertise in neuroscience, particularly synaptic biology and neural circuit dynamics, with notable contributions to understanding cortical plasticity and hippocampal function. His lab has trained students like Sandra Reinert and Matthew McCann through the GSN program.

• DNA Damage and Repair
• Molecular Oncology
• Cancer Biology
• +۳ مورد دیگر

Peter McHugh is Professor of Molecular Oncology at the University of Oxford, serving as Director of Oncology Laboratories at the Weatherall Institute of Molecular Medicine (WIMM) and Head of the DNA Damage and Repair Group within the Department of Oncology. His research focuses on understanding DNA damage and repair mechanisms to elucidate cancer causes and improve treatment strategies. McHugh completed his D.Phil in Biochemistry at the University of Oxford in 1996, following a BSc (Hons) in Biochemistry from UMIST in 1991. His postdoctoral training included positions as a Post-Doctoral Fellow at University College London (1997-2001) and as a Royal Society Research Fellow at UCL (2001-2002). His research program centers on molecular mechanisms of DNA repair pathways, particularly investigating nucleases like SNM1A and repair processes for complex DNA damage including interstrand crosslinks. McHugh's work spans structural biology, biochemical characterization of repair enzymes, and translational applications for cancer therapy. His laboratory employs approaches ranging from single-molecule analysis to cellular and animal models to understand how DNA repair deficiencies contribute to cancer development and how these pathways can be targeted therapeutically. Analysis of his recent publications reveals a consistent focus on DNA-protein crosslink repair, nuclease mechanisms, and the development of targeted cancer therapies. His work demonstrates strong interdisciplinary connections between basic DNA repair mechanisms and clinical oncology applications, with particular emphasis on identifying novel therapeutic targets within DNA repair pathways. Royal Society Research Fellow (2001-2002) As Director of Oncology Laboratories at WIMM and Head of the DNA Damage and Repair Group, Professor McHugh oversees significant research infrastructure and leads a team investigating fundamental mechanisms of genome maintenance. His work has implications for understanding cancer predisposition syndromes and developing targeted therapies that exploit DNA repair deficiencies in cancer cells. His laboratory maintains active collaborations across molecular oncology, structural biology, and translational medicine disciplines. The McHugh Group at the WIMM operates state-of-the-art facilities for DNA repair research, with expertise in biochemical reconstitution of repair pathways, cellular DNA damage response analysis, and development of chemical tools to probe repair mechanisms. The group maintains strong connections with clinical oncology researchers to bridge basic science discoveries with therapeutic applications.

Jin Mo Chungمشاهده پروفایل

استاد

• Chronic Pain
• Neuropathic Pain
• Synaptic Plasticity
• +۷ مورد دیگر

Jin Mo Chung is a Professor and Chair at the University of Texas Medical Branch (UTMB), holding the Cecil H. and Ida M. Green Distinguished University Endowed Chair in Neuroscience and Cell Biology. His work focuses on chronic pain mechanisms, particularly neuropathic pain, where he developed the foundational 'spinal nerve ligation (SNL) Chung Model' for testing analgesics. With over 160 peer-reviewed publications and 23,000 citations, his research has been NIH-funded for 35 years, including multiple R01 and Program Project Grants. Education: BS in Physics, Sogang University PhD in Physiology, Loyola-Stritch School of Medicine Post-Doctoral in Neurophysiology, Loyola-Stritch Post-Doctoral in Somatosensory Neurophysiology, UTMB Chung's research spans synaptic plasticity in pain pathways, reactive oxygen species (ROS) in chronic pain, and treatment strategies for conditions like spinal cord injury, diabetic neuropathy, HIV infection, and chemotherapy-induced pain. He has pioneered animal models for pain research and explored interventions like spinal cord stimulation, antioxidant therapy, and electroacupuncture. The 15 most recent articles reflect a focus on pain neurobiology, ROS signaling, neuroinflammation, and neuromodulation techniques. Key subfields include FGF13 in diabetic neuropathy, Wnt5a signaling in HIV-related pain, opioid-induced hyperalgesia, circadian regulation of chemotherapy pain, and neuron-type-specific spinal cord stimulation. Scientific Contributions: Developed the 'Chung Model' of spinal nerve ligation Over 160 peer-reviewed publications NIH R01 and Program Project Grants (35 years) Co-editor of Encyclopedia of Pain Chung has mentored 30 postdoctoral fellows and 22 visiting scientists. He co-founded the Association of Korean Neuroscientists and led the Gulf Coast Consortium and Texas Pain Research Consortium. His work connects basic science to clinical applications, with global impacts on analgesic drug development.

Saumen Sarkarمشاهده پروفایل

استاد

• Type I Interferon Signaling
• Antiviral Innate Immunity
• IFN-Stimulated Genes
• +۴ مورد دیگر

Dr. Saumen Sarkar is a Professor in the Department of Microbiology and Immunology at the University of Maryland School of Medicine, with an additional appointment in the Program in Oncology. His research focuses on innate immune signaling during viral infections and cancer, particularly mechanisms of type I interferon (IFN) induction and modulation by host components like the OAS family genes. He has authored over 77 publications spanning virology, immunology, and molecular biology. Education: PhD in Molecular Biophysics (Indian Institute of Science), MSc in Biophysics (University of Calcutta), BSc (University of Calcutta) His work explores the dual antiviral and antibacterial functions of OAS1, interactions between RIG-I and OASL, and the role of interferon regulatory factors in tumor progression and immunotherapy. Key contributions include elucidating how OASL enhances RIG-I signaling and identifying novel immune-modulating roles for TLR3 tyrosine residues. Recent publications (2024) highlight OAS1's mechanisms in translational shutdown during viral infection and its newly discovered antibacterial functions via IRF1. Earlier work (2019-2010) addresses DNA virus immune evasion, MAVS regulation, and translational research in head/neck cancers. Dr. Sarkar's research integrates structural biology (e.g., 2003 OAS crystal structure) and systems approaches (2024 cell-type-specific networks) to understand host-pathogen interactions and tumor immunity.

Andrea De Vizcaya Ruizمشاهده پروفایل

استاد

• Environmental Toxicology
• Particulate Matter (PM2.5/PM10)
• Nanotoxicology
• +۴ مورد دیگر

Andrea De Vizcaya Ruiz is a Professor in the Department of Environmental and Occupational Health at the University of California, Irvine (UCI) School of Public Health . She is Graduate Program Director for Environmental Health Sciences and leads research at key centers including the Center for Occupational and Environmental Health (COEH) , Air Pollution Health Effects Lab (APHEL) , and AirUCI Atmospheric Integrated Research Unit . Her expertise spans environmental toxicology, nanotoxicology, and air pollution health impacts , with a focus on particulate matter (PM), microplastics, and nanomaterials. Educational Background: Bachelor's in Veterinary Medicine, National Autonomous University of Mexico (UNAM) Doctorate in Toxicology, University of Surrey, UK Research Interests center on toxic effects of environmental pollutants , including: Health impacts of particulate matter (PM2.5/PM10) Toxicokinetics of nanomaterials Oxidative stress and inflammation mechanisms Health equity in environmental exposure Neurotoxic and cardiorespiratory effects Biomarker development for toxicity assessment Recent Publications highlight her work on PM-induced nephrotoxicity, nanoparticle neurotoxicity, and synergies between urban pollutants and metabolic stressors . Her studies frequently employ in vitro and in vivo models to dissect toxicity pathways. Scientific Awards: 2011 Young Investigator Award, Society of Toxicology, USA 2015 1st place BioNanoTechnology Award, Cinvestav and Neolpharma Inc., Mexico City Student Mentorship includes advising PhD and MSc students like Aidee Solorio Rodriguez and Josefina Poblano Bata, with their work presented at international conferences including the International Nanotoxicology Congress and IUTOX Trainee Awards. Labs & Collaborations: She actively collaborates with research groups in Mexico, the Netherlands, Canada, and the US, integrating toxicology, aerosol science, and public health to address evolving biotechnology challenges. Her advisory roles for the Mexican Ministry of Health and Environment further demonstrate her policy impact.