جستجوی استاد راهنمای دانشگاهی

Leonid Brownمشاهده پروفایل

استاد

• Biophysics
• Membrane proteins
• Spectroscopy
• +۷ مورد دیگر

Leonid Brown is a full Professor in the Department of Physics at the University of Guelph, Canada, specializing in biophysics with a focus on membrane proteins. His research integrates molecular biology with advanced biophysical techniques to study the structure and function of light-sensitive proteins. Dr. Brown's primary research interests include biophysics of membrane proteins , particularly microbial rhodopsins and aquaporins. His work combines molecular biology with modern biophysical methods including time-resolved spectroscopy in the visible range, Fourier-transform infrared spectroscopy, nuclear magnetic resonance, and Raman spectroscopy. His research specifically focuses on exploring novel microbial rhodopsins for optogenetic applications and studying protein-lipid interactions in membrane proteins. His recent publications (2022-2025) demonstrate a strong focus on understanding the structural foundations of ion selectivity in channelrhodopsins, proton transfer mechanisms in light-driven pumps, and the role of hydrogen-bonding networks in membrane protein function. These studies employ advanced techniques including cryo-electron microscopy, solid-state NMR, and computational modeling to elucidate atomic-level details of protein structure and function. Member of Editorial Board of the Biophysical Journal (2009-2015 and 2024) Premier's Research Excellence Award (2003) Research Innovation Award (2003) Member of the Canadian Biophysical Society Executive (2019-2022) DAAD and Ontario-Baden-Württemberg scholarships (2016) Dr. Brown has established collaborative research partnerships with institutions worldwide, including Nagoya Institute of Technology in Japan and Sogang University in Korea. His laboratory develops and utilizes high-end instrumentation including time-resolved vacuum infrared spectrometers, Raman/FTIR combination spectrometers, and time-resolved visible range laser spectrometers. His research has significant implications for optogenetics and potential medical applications, with media coverage in outlets like The Scientist and Health Canal for discoveries related to heart disease treatment.

• Neuroscience
• Biomedical Engineering
• Neural Dynamics
• +۳ مورد دیگر

Vladislav Myrov is a Postdoctoral Researcher at Aalto University's Department of Neuroscience and Biomedical Engineering. His research spans neural dynamics, brain criticality, and computational modeling of cognitive processes. Key research interests include: Neuronal oscillations and synchronization Computational neuroscience of perception Criticality in brain networks Neurogenetic influences on neural dynamics Recent publications focus on quantifying brain state transitions, modeling visual illusions, and analyzing synchronization patterns in clinical contexts. Myrov collaborates across disciplines in neurology and cognitive psychology.

Azahara Olivaمشاهده پروفایل

استادیار

• Neuroscience
• Memory Systems
• Brain Dynamics
• +۳ مورد دیگر

Azahara Oliva is an Assistant Professor in the Department of Neurobiology and Behavior at Cornell University's College of Arts and Sciences. Her research focuses on understanding how global brain states modulate local network activity during learning, memory, and sleep, with a particular emphasis on hippocampal and cortical circuits. Research Themes: Neural coordination across brain regions Role of brain states in memory consolidation Computational tools for analyzing neural dynamics Integration of experimental and theoretical approaches Key Methodologies: Large-scale depth electrodes (Neuropixels), closed-loop optogenetics, fiber photometry, and data mining techniques applied to single-cell and population-level neural activity. Scientific Recognition: Suffrage Science Award Klarman Fellow

• Opioid Receptor Pharmacology
• Pain Neurobiology
• Addiction Neuroscience
• +۳ مورد دیگر

Nicolas Massaly is an Assistant Professor in the Department of Anesthesiology , David Geffen School of Medicine at University of California, Los Angeles (UCLA) . His research focuses on the intersection of pain neurobiology, opioid pharmacology, and addiction neuroscience , with particular emphasis on opioid receptor dynamics, neural circuitry in addiction, and non-addictive pain therapies . Key research areas: Opioid receptor antagonism, pain-addiction comorbidity, neuroimmune interactions, and biomedical device development for overdose prevention Academic contributions: 15+ peer-reviewed publications (2010-2025) in journals like Nature Neuroscience , Neuron , and Science , covering opioid system dysregulation, pain-induced behavioral adaptations, and receptor-specific pharmacology Collaborative networks: Active in opioid research with co-authors including Catherine Cahill (UCLA) and J. Anthony Morón (Washington University) Current affiliations: Maintains research presence in UCLA's Department of Anesthesiology with focus on translational studies from rodent models to clinical applications His work has been cited in 100+ publications and highlighted across academic networks, news outlets, and social media , indicating significant impact in addressing the opioid epidemic through neuropharmacological and technological innovations .

Ryan S. Grayمشاهده پروفایل

دانشیار

• Musculoskeletal Disease
• Developmental Biology
• Genetics
• +۴ مورد دیگر

Ryan S. Gray, Ph.D. is an Associate Professor in the Department of Pediatrics at The University of Texas at Austin , with an adjunct faculty appointment in the Department of Nutritional Sciences within the College of Natural Sciences . Education: Ph.D. in Cellular and Molecular Biology from UT Austin Postdoctoral Training: Washington University School of Medicine Gray's research focuses on musculoskeletal diseases , particularly adolescent idiopathic scoliosis (AIS) and cartilage degeneration . His lab employs a multi-tiered approach combining zebrafish , mouse , and cell culture models informed by human genomics to uncover mechanisms of spine development and disease. Key areas include: Genetic regulation of spine morphogenesis Role of cilia in cerebrospinal fluid dynamics Protein assembly in vertebrate evolution ADGRG6 and SOX9 signaling in cartilage homeostasis His publications highlight novel genetic pathways in AIS, including Kif6 , Inppl1a , and dysregulated dynein genes . Awards include the Early Investigator Podium Award (2017) and Best Poster Award (2015) from leading orthopedic societies. Gray leads the Gray Lab , which emphasizes translational research for musculoskeletal disorders. The lab's work spans from basic science (e.g., kinesin motor proteins) to clinical applications in scoliosis diagnosis and treatment.

Edoardo Sozziمشاهده پروفایل

پژوهشگر ارشد

• Neuroscience
• Neurobiology
• Stem Cell Research
• +۶ مورد دیگر

Edoardo Sozzi is a Visiting Research Fellow and PhD student at Lund University's Faculty of Medicine, specializing in the Developmental and Regenerative Neurobiology group under Prof. Malin Parmar. He earned a BSc in Biotechnology (2018) and a dual MSc in Neuroscience (2020) from the University of Pisa and Scuola Normale Superiore, Italy. His research focuses on the development, functionality, and diversity of human dopaminergic neurons using 3D cell culture systems like brain organoids and xenograft models, with heavy reliance on single-cell RNA sequencing. His work intersects neuroscience, developmental biology, and regenerative medicine, targeting neurodegenerative disorders such as Parkinson's disease. Key publication trends include innovations in organoid technology , single-cell transcriptomics , and WNT signaling modulation . He has contributed to 11 scientific outputs , including a 2025 doctoral thesis, peer-reviewed articles in Nature Methods and Development , and a 2023 Horizon Europe grant (OpenMIND project) for opto-electronic neural modeling in neurodegenerative diseases. Sozzi actively participates in academic events, organizing conferences like Neuroscience Day 2024 and UniStem Day 2024 , and serves as a presenter in multidisciplinary initiatives (MultiPark). His work aligns with UN Sustainable Development Goals for Medical and Health Sciences and Neurosciences .

Sylvie Friantمشاهده پروفایل

پژوهشگر

• Membrane Trafficking
• Lipid Signaling
• Yeast Model Organism
• +۴ مورد دیگر

Sylvie Friant is a Senior Researcher (DR2) at the CNRS , leading the "Membrane Trafficking and Lipid Signaling" team at the University of Strasbourg's Department of Molecular and Cellular Biology since 2006. Her research explores the intersection of cell biology , lipid signaling , and human disease modeling using yeast ( Saccharomyces cerevisiae ) as a eukaryotic model organism. Education 2006: Habilitation to Direct Research (HDR), University of Strasbourg 1997: PhD in Molecular and Cellular Biology, University Louis Pasteur 1994: Master in Molecular and Cellular Biology, University of Strasbourg 1992: Bachelor in Biochemistry, University of Strasbourg Her work focuses on membrane trafficking , phosphoinositide signaling , and yeast-based human disease models , particularly for ciliopathies and neuromuscular disorders . Recent studies investigate PYROXD1 mutations in limb-girdle muscular dystrophy, VPS15/PIK3R4's role in retinitis pigmentosa, and MTMR2/MTM1 interactions in myopathies. Scientific contributions include CNRS Bronze Medal (2005) CNRS ATIP Starting Grant (2005) AcademiaNet nominee (2016) She has directed multiple PhD projects (e.g., Matthieu Raess) and secured grants from AFM-Téléthon, IdEx, and national institutions. Her team moved to the Strasbourg Biomedical Research Center (CRBS) in 2025.

Rongxin Fangمشاهده پروفایل

استادیار

• Genomics
• Neuroscience
• Computational Biology
• +۶ مورد دیگر

Rongxin Fang is an Assistant Professor of Neurosurgery and Genetics (by courtesy) at Stanford University. He received his Ph.D. in Bioinformatics and Systems Biology from UC San Diego (2015-2019) and completed a postdoctoral fellowship in Spatial Genomics at Harvard University (2019-2024). His work bridges high-throughput genomic technologies, computational tools, and transcriptome imaging to unravel the molecular architecture of the brain across species and developmental stages. Research Highlights: Developed 3D MERFISH imaging for thick tissues (2024), enabling spatial genomics at unprecedented resolution. Led cross-species MERFISH studies (2022) revealing conserved cortical organization with human-specific glia-neuron interactions. Created SnapATAC (2021), a pivotal tool for large-scale single-cell ATAC-seq analysis. Scientific Awards: Damon Runyon-Dale F. Frey Award for Breakthrough Scientists (2024) Next Generation Leader, Allen Institute (2024) Rising Star in Health in Engineering (2022) Advising and Collaborations: Doctoral Dissertation Advisor for Eduardo Chaparro Barriera Postdoctoral Faculty Sponsor for Ya Jiang Collaborated with Xiaowei Zhuang (Harvard), Adam Cohen (Harvard), and Bing Ren (UCSD)

Stephan Neuhaussمشاهده پروفایل

استاد

• Visual system development
• Retinal biology
• Zebrafish genetics
• +۶ مورد دیگر

Prof. Dr. Stephan Neuhauss leads the Molecular Life Sciences research group at the University of Zurich's Faculty of Science. His lab specializes in zebrafish models for studying retinal biology, visual system development, and heritable human diseases. The Neuhauss Lab has made significant contributions to understanding photoreceptor function, glutamate signaling, and ciliopathies through genetic and physiological approaches. Research Focus : Retinal phototransduction mechanisms Zebrafish models for medulloblastoma Glutamate homeostasis in CNS Evolution of vision-related gene families Scientific Trends : His 15 most recent publications (2016-2025) reveal a strong focus on zebrafish genetics, retinal disorders, and innovative biomedical technologies. Key subfields include photoreceptor biology, ciliary gene function, synaptic transmission mechanisms, and translational cancer research. Recognition : Best Presentation Awards (2025) SNF Förderprofessorship (2019) CandDoc Forschungskredit (2018) Academic Leadership : As Vice-Dean for Research and Planning (2017-), he has shaped Zurich's scientific landscape while mentoring numerous PhD and Master's students including Jingjing Zang, Irene Ojeda Naharros, and Ruxandra Bachmann-Gagescu.

Christian Klämbtمشاهده پروفایل

استاد

• Drosophila glial cell development and function
• receptor tyrosine kinase signaling and differentiation
• neuron-glial interaction
• +۲ مورد دیگر

Prof. Dr. Christian Klämbt is a distinguished faculty member at the Institute of Neuro- and Behavioral Biology , University of Münster. His work bridges developmental biology , behavioral biology , and molecular neurobiology , focusing on Drosophila melanogaster as a model organism. Research profile: Glial cell development, neuron-glial interactions, receptor tyrosine kinase signaling, and blood-brain barrier dynamics. Key technologies: FIM (Frustrated Internal Reflection Microscopy) for locomotion analysis, advanced imaging tools, and Drosophila genetic manipulation. Research Interests: Klämbt’s group investigates glial cell roles in brain function, emphasizing their involvement in axonal wrapping , blood-brain barrier integrity , and behavioral regulation . His work highlights the conserved functions of glia across species. Publication Trends: Recent articles focus on glial differentiation , neuronal signaling , and imaging technologies . Themes include Drosophila glial development , metabolic regulation , and neuroimmune interactions . Additional Roles: Active member of the Cells in Motion cluster, CiM-IMPRS graduate program , and Imaging Network . Co-inventor of a patent for animal detection systems.

Michael Krahnمشاهده پروفایل

استاد

• biomolecular label chemistry
• RNA biochemistry
• bioorthogonal chemistry
• +۷ مورد دیگر

Michael Krahn is a University Professor at the University of Münster's Faculty of Medicine, where he leads the Medical Cell Biology research group within Medical Clinic D - Internal Medicine. Holding dual doctorates in Veterinary Medicine and Natural Sciences, he maintains an active research program focusing on molecular mechanisms of cell biology with particular emphasis on membrane dynamics and cellular structures. His research interests span biomolecular label chemistry, RNA biochemistry, bioorthogonal chemistry, RNA modifications, nucleic acid chemistry, chemical biology, and mRNA. Professor Krahn's work particularly explores how phosphoinositide lipids regulate cell polarity and membrane organization, with significant contributions to understanding slit diaphragm formation, endocytosis, and related disease mechanisms. His publication record shows consistent research output through 2023, with recent work examining tight junction formation, ER stress responses in podocytes, Hippo pathway regulation, and SEC61A1 variants in liver disease. These publications demonstrate his interdisciplinary approach bridging cell biology, molecular medicine, and disease pathology, primarily using Drosophila models and mammalian cell systems. Professor Krahn participates in the "Cells in Motion" collaborative research initiative and is a member of the Imaging Network, focusing on microscopy applications for cellular dynamics research. His work appears in high-impact journals including Nature Communications, Cell Reports, and Journal of the American Society of Nephrology, reflecting the significance of his contributions to cell polarity and membrane biology fields.

Jun Yangمشاهده پروفایل

استاد

• Photoreceptor Biology
• Retinal Degeneration
• Usher Syndrome
• +۴ مورد دیگر

Jun Yang is a Professor at the Department of Ophthalmology and Visual Sciences and Adjunct Professor in Neurobiology at University of Utah Health. His research focuses on the genetics and cell biology of photoreceptors and hair cells, particularly in relation to Usher syndrome and retinal degeneration. Education: B.S. from Nankai University, Ph.D. from University of Massachusetts Amherst Yang's lab investigates molecular mechanisms of heritable retinal degeneration, including photoreceptor trafficking, calcium regulation, and the multi-protein Usher II complex. His work explores gene therapy approaches using AAV vectors to treat mouse models of retinal diseases. The 15 most recent publications highlight studies on CFAP418-lipid interactions, USH2 complex integrity, photoreceptor disc morphogenesis, TRPV1 channel regulation, and stereocilia development. These works span molecular genetics, protein biochemistry, and translational therapies for sensory cilia disorders. His research has been published in journals like JCI Insight , Human Molecular Genetics , and PLoS Genetics , with a focus on protein-protein interactions, ciliary rootlet structure, and membrane homeostasis. Collaborative projects include studies on cytomegalovirus-induced hearing loss and therapeutic interventions. Jun Yang's laboratory at University of Utah Health employs mouse genetics, molecular biology, and advanced microscopy to understand and develop treatments for retinal and auditory degeneration diseases.

Matt Wachowiakمشاهده پروفایل

استاد

• Neurobiology
• Neural Coding
• Sensory Processing
• +۴ مورد دیگر

Matt Wachowiak is a Professor of Neurobiology at the University of Utah School of Medicine, where he leads an active research laboratory focused on neural coding and circuit mechanisms underlying sensory processing and perception. His work primarily utilizes the mouse olfactory system as a model to investigate how neural circuits transform sensory representations and how animals actively acquire sensory information to guide goal-directed behavior. Dr. Wachowiak received his B.S. from Duke University in 1990, followed by a Ph.D. from the University of Florida in 1996. He completed his postdoctoral training at Yale University School of Medicine from 1998-2002 before establishing his independent research program at the University of Utah. His research focuses on how neurons in the brain represent and process information about the external world, with particular emphasis on the dynamics of neural circuits during sensory processing. Dr. Wachowiak's laboratory employs advanced optical techniques including two-photon imaging of neural activity in awake behaving animals, combined with measurements of sampling behavior and behavioral readouts of odor perception. They use genetically-targeted optical reporters to study specific neuron populations and employ genetic and optical tools to perturb neural subpopulations to dissect circuit functions. Analysis of Dr. Wachowiak's recent publications reveals a consistent focus on the neural mechanisms of olfactory processing, with particular attention to how inhalation dynamics, neural inhibition, and circuit architecture shape odor representations. His work spans multiple levels of analysis from cellular mechanisms to systems-level processing, with increasing emphasis on computational approaches to understanding sensory coding. Dr. Wachowiak maintains an active laboratory (The Wachowiak Lab) at the University of Utah that has produced numerous publications in high-impact journals including Nature Communications, Neuron, Journal of Neuroscience, and eLife. His research program appears well-funded based on the consistent publication output and methodological sophistication of the work. The laboratory employs a range of advanced techniques including two-photon microscopy, genetic targeting, behavioral analysis, and computational modeling to address fundamental questions about sensory processing and neural coding.

• Molecular Biology
• Genetics
• Cell Biology
• +۶ مورد دیگر

Ingolf Bach is a Professor at the UMass Chan Medical School , affiliated with multiple departments including Molecular, Cell and Cancer Biology , NeuroNexus Institute , and Program in Molecular Medicine . His research focuses on LIM domain proteins and their associated cofactors, such as RLIM/Rnf12 and CLIM/Ldb , which play critical roles in cell fate specification, X chromosome inactivation , and mammary gland development . Education: University of Konstanz , Germany: BA in Biology, MA in Molecular Biology Paris Diderot University , France: PhD in Biotechnology Research Interests: Dr. Bach investigates how protein complexes regulate gene expression during development and disease. Key areas include X chromosome inactivation in female mice, neuronal differentiation , and breast cancer mechanisms. His lab employs molecular , biochemical , and genetic approaches using mouse models. Publications: His recent work spans Xist gene regulation , germ cell specification , and metabolic control via RLIM , with studies in journals like Nature , Cell , and EMBO J . Keywords include Molecular Biology , Genetics , and Developmental Biology . Advising and Collaborations: Dr. Bach mentors students in PhD rotation projects and offers postdoctoral positions . He collaborates with institutions such as the Pasteur Institute and University of Hamburg . Labs and Teams: His laboratory at UMass Chan explores X chromosome inactivation , neuronal development , and mammary gland biology , utilizing mouse genetics and biochemical techniques.

Shane Crandallمشاهده پروفایل

استادیار

• Neuroscience
• Systems Neuroscience
• Cortical Circuits
• +۴ مورد دیگر

Shane Crandall serves as Assistant Professor in the Department of Physiology and BioMolecular Science Gateway at Michigan State University, where he directs research in the Neuroscience Program. His laboratory operates from the Biomedical Physical Sciences Building (Room 2100) in East Lansing, Michigan. His academic training includes: B.A. in Neuroscience, Boston University (2005) Ph.D. in Neuroscience, University of Illinois Urbana-Champaign (2012) Postdoctoral Fellowship, Brown University (2012-2017) Dr. Crandall's research program investigates neural circuit mechanisms underlying sensory perception, with primary focus on dynamic neocortex-thalamus interactions. His laboratory examines how these circuits process signals essential for sensation, movement, and cognition, and how their dysfunction contributes to neurological disorders including epilepsy and Tuberous Sclerosis Complex (TSC). Key methodologies include: Electrophysiological and optical recording in awake behaving mice Multi-scale circuit analysis from single neurons to network dynamics Studies of corticothalamic and intracortical pathway modulation TSC-related circuit abnormality characterization Analysis of recent publications (2022-2024) reveals intensifying focus on layer 6 corticothalamic feedback circuits and motor-sensory integration. His team employs selective optical stimulation to dissect parallel pathways, demonstrating how specific interneuron subtypes (particularly somatostatin-expressing) mediate top-down modulation of somatosensory processing. This work establishes critical links between circuit dynamics and neurological disease mechanisms. Dr. Crandall actively mentors postdoctoral researchers, Ph.D. students, and undergraduates, with current recruitment ongoing for all levels. His laboratory maintains strong collaborative ties within MSU's Neuroscience Program and Department of Physiology. The research facility in Biomedical Physical Sciences Building integrates advanced electrophysiology with optical techniques for comprehensive neural circuit analysis in both in vitro and awake behaving preparations, supporting investigations into fundamental sensory processing mechanisms and disease models.