جست‌وجوی استاد و پژوهشگر

• Genomics
• Non-coding RNA research
• Phenotype-genotype relationships
• +۷ مورد دیگر

Professor Marcel Dinger is a prominent academic and researcher currently serving as Professor and Head of School for Biotechnology and Biomolecular Sciences at UNSW Sydney. With over 20 years of experience in genomics, he has established himself as a leading figure in both academic and entrepreneurial spheres within the field. He has published 153 papers with over 24,000 citations and maintains an h-index of 61 on Google Scholar. His leadership extends beyond academia as he serves as President of the Australasian Genomics Technologies Association (AGTA) and holds director positions at Pryzm Health and the National Centre for Indigenous Genomics (NCIG). Professor Dinger's research laboratory focuses on establishing new links between phenotype and genotype, particularly examining rare and complex diseases in relation to underexplored regions of the genome including pseudogenes, repetitive elements, non-canonical DNA structures, and noncoding RNAs. His work harnesses population-scale genomic datasets and sophisticated data science methods to bring an objective perspective to understanding how the genome stores information and how it is transacted in biology. His research interests span genomics, non-coding RNA biology, clinical applications of genomic medicine, and the development of computational approaches for analyzing complex genomic data. Analysis of Professor Dinger's recent publications reveals a strong emphasis on non-coding RNA research, particularly long noncoding RNAs and their roles in disease mechanisms. His work spans cancer genomics, neurological disorders, and fundamental genomic mechanisms including DNA secondary structures like i-motifs and G-quadruplexes. His research combines experimental approaches with advanced bioinformatics to address fundamental questions in genomic medicine and has significant translational implications for disease diagnosis and treatment. Highly Cited Researcher in Cross-Field category (2019, 2020, 2021) Fellow of the Faculty of Science (Research), Royal Society of Pathologists of Australasia (2016) NHMRC Career Development Award (2010) Queensland Government Smart Futures Fellowship (2009) Foundation of Research, Science and Technology New Zealand Postdoctoral Fellowship (2005) Professor Dinger has been instrumental in establishing and leading several significant research initiatives including Genome.One, one of the first companies globally to provide clinical whole genome sequencing services, and the Kinghorn Centre for Clinical Genomics at the Garvan Institute of Medical Research. His entrepreneurial experience includes founding four biotechnology and IT startups. He serves on multiple governance boards including the National Centre for Indigenous Genomics, focusing on using genomics to improve health outcomes for Australia's First Peoples. His laboratory at UNSW continues to advance our understanding of genomic regulation and its implications for human health and disease.

Kai-Hsiang Chuangمشاهده پروفایل

دانشیار

• Functional brain mapping
• Brain network in learning, memory and dementia
• Brain waste clearance
• +۷ مورد دیگر

Associate Professor Kai-Hsiang Chuang is a Principal Research Fellow at the School of Biomedical Sciences within the Faculty of Health, Medicine and Behavioural Sciences at the University of Queensland. He is also affiliated with the Queensland Brain Institute and the Centre for Advanced Imaging. His research focuses on understanding brain networks, developing advanced imaging techniques, and translating these findings to improve diagnosis and intervention for neurological disorders. Dr. Chuang received his Ph.D. in electrical and biomedical engineering from the National Taiwan University, Taiwan, in 2001. His doctoral research focused on improving the detection of brain activity using functional magnetic resonance imaging (fMRI). Ph.D. in Electrical and Biomedical Engineering, National Taiwan University (2001) Dr. Chuang's research spans multiple areas of brain imaging and neuroscience. His primary focus is on functional brain mapping , where he develops in vivo imaging techniques including functional MRI and multimodal integration with optogenetics, calcium imaging, and electrophysiology. He applies these techniques in both humans and animal models to improve understanding and intervention of brain function, disease processes, and treatment effects. Another key area is brain networks in learning, memory, and dementia . His work explores how brain network wiring and activity underpin cognition and behavior, with particular focus on understanding the causal relationship between brain network activity and memory formation. He develops techniques to modulate behavior by manipulating brain network activity. More recently, Dr. Chuang has expanded into brain waste clearance research, studying the brain's fluid drainage system that clears waste and toxic molecules like amyloid plaques. His lab is developing imaging techniques to track this system's function and understand its regulatory mechanisms, which could provide new treatment targets for dementia. Analysis of Dr. Chuang's recent publications reveals a strong focus on advancing functional MRI techniques for brain network analysis, particularly in rodent models. His work consistently bridges basic neuroscience with clinical applications, especially in understanding memory formation and dementia. A notable trend is the development of multimodal approaches that combine fMRI with optogenetics, calcium imaging, and electrophysiology to establish causal relationships in brain networks. His research increasingly addresses the translation of preclinical findings to human applications, with growing emphasis on Alzheimer's disease mechanisms and potential interventions. Dr. Chuang serves on the editorial boards of multiple prestigious journals including Frontiers in Neuroscience: Brain Imaging Methods , Imaging Neuroscience , and Scientific Reports , reflecting his standing in the field. Editorial Board Member, Frontiers in Neuroscience: Brain Imaging Methods Editorial Board Member, Imaging Neuroscience Editorial Board Member, Scientific Reports Dr. Chuang is actively involved in research supervision, currently serving as Principal Advisor for one PhD student working on "Developing imaging and neuro-technologies for decoding memory formation" and Associate Advisor for two other PhD projects. He has successfully completed supervision of three PhD students on topics related to resting-state networks, memory consolidation, and functional MRI. ARC Discovery Projects (2024-2028): "Decoding the brain network of memory formation" ARC Training Centre for Innovation in Biomedical Imaging Technology (2017-2024) NHMRC-NIH BRAIN Initiative Collaborative Research Grants (2016-2023) Universities Australia - Germany Joint Research Co-operation Scheme (2017-2018) Mater Medical Research Institute Limited grant for mindfulness-based cognitive therapy research (2017-2020) Dr. Chuang leads the Functional and Molecular Neuroimaging Group at the Queensland Brain Institute. His laboratory focuses on understanding the functional connectome of the brain and developing functional and molecular imaging techniques to study brain connectivity associated with behavior. The group has developed various MRI techniques to track neuronal connections, map large-scale brain synchrony, and quantify cerebral blood flow and metabolism in vivo. His research team collaborates extensively with other experts at UQ and internationally, including collaborations with Associate Professor Darryl Eyles, Professor Jürgen Götz, Professor Tianzi Jiang, Dr. Fatima Nasrallah, Professor Linda J. Richards, Professor Pankaj Sah, Professor Elizabeth Coulson, Dr. Patricio Opazo, Professor Feng Liu, and Professor Markus Barth.

Zeynep Erson Omayمشاهده پروفایل

استادیار

• Computational Biology
• Genomics
• Epigenomics
• +۶ مورد دیگر

Dr. Zeynep Erson Omay serves as an Assistant Professor in the Department of Neurosurgery and Biomedical Informatics & Data Science at Yale School of Medicine. Her work bridges computational biology with neurosurgical oncology, focusing on precision medicine applications for brain tumors, with particular emphasis on understanding tumor heterogeneity and molecular mechanisms of CNS tumors. Dr. Erson Omay's educational background includes: PhD in Computer Science from Case Western Reserve University (2011) MS in Computer Science from Bilkent University (2005) BS in Computer Science from Bilkent University (2003) Her research focuses on computational analysis of multi-omic datasets to understand tumor heterogeneity, particularly in central nervous system tumors. Dr. Erson Omay specializes in genomic, transcriptomic, and epigenetic profiling of brain tumors, with emphasis on meningiomas, glioblastomas, and rare CNS tumor subtypes. She leads the Erson Lab, which develops bioinformatics approaches to study large datasets and reveal molecular mechanisms in tumor formation, progression, and clinical outlier subgroups. Her work in precision medicine aims to decipher the molecular architecture of individual tumors to guide personalized treatment approaches, with significant contributions to understanding tumor ecosystems and evolutionary patterns in brain cancers. Dr. Erson Omay's scientific contributions span neuro-oncology, computational biology, and precision medicine, with a strong emphasis on translating genomic findings into clinical applications. Her publications demonstrate consistent innovation in applying computational methods to complex neurosurgical problems, with particular focus on tumor heterogeneity, molecular classification, and racial disparities in tumor genomics. Her notable scientific awards include: 10x Genomics 2021 Pilot Award (2022) Mission Bio Tapestri Grant (2022) Case Western Reserve University, Research ShowCASE-Best Poster Award (2007) Dr. Erson Omay actively mentors students and researchers at various levels, including undergraduate students, graduate students, postdocs, and postgraduate associates. She collaborates extensively within Yale's neurosurgery department and across disciplines to advance computational approaches to brain tumor research. Her work is supported by various grants that enable the development of novel bioinformatics platforms for tumor genomic characterization. She leads the Erson Lab, which focuses on three major research areas: Tumor Ecosystem (studying interactions among tumor and immune cells), Tumor Evolution and Heterogeneity (understanding temporal and spatial tumor evolution), and Precision Medicine (applying genomic techniques to personalize brain tumor treatment). The lab employs diverse omics technologies to explore brain tumor biology and develop computational methods for precision medicine applications.

Nick Virgilioمشاهده پروفایل

استاد

• Thermodynamics
• Multiphase systems
• Surfaces, interfaces and thin layers
• +۲ مورد دیگر

Nick Virgilio is a Full Professor in the Department of Chemical Engineering at Polytechnique Montréal . His research focuses on soft matter interfaces, polymer blends, and advanced hydrogel systems for biomedical and catalytic applications. Director, Research Laboratory on Surfaces, Interfaces and Soft Matter Member, Research Center for High-Performance Polymer and Composite Systems (CREPEC) Research interests include interfacial phenomena in multiphase systems, self-assembly of soft materials, nanoparticle-hydrogel composites, Pickering emulsions, and polymer microstructure engineering. Scientific awards include the 2010 Canadian Macromolecular Science Thesis Prize and the 2004 Polytechnique Montréal Master's Thesis Award. Recent publications highlight his work in macroporous hydrogels for cancer cell capture, nanoparticle synthesis in soft matrices, and interfacial control of polymer blends. His studies frequently appear in high-impact journals like ACS Applied Materials & Interfaces , Green Chemistry , and Macromolecules . Students under his supervision have explored topics from biofilm mechanics to lunar environment polymer systems across 4 PhD and 6 Master’s theses completed or ongoing.

Ville Paavilainenمشاهده پروفایل

پژوهشگر

• Biochemistry
• Cell Biology
• Molecular Biology
• +۹ مورد دیگر

Ville Paavilainen is a Research Director at the Institute of Biotechnology, University of Helsinki, and supervisor for doctoral programs in Biomedicine and Integrative Life Science. With a postdoctoral background at the University of California, San Francisco (2008–2014), he focuses on Biochemistry , Cell Biology , and Molecular Biology , particularly mechanisms of protein translocation, membrane biology, and structural modeling. His research includes groundbreaking work on Sec61 translocon inhibition for cancer therapy and mitochondrial gene expression noise . Recent publications address lipid scrambling pathways, glioma stem cell targeting, and actin regulation. Active projects span EU-funded drug discovery and NIH collaborations. Key scientific contributions include Elucidating Sec61-client interactions Developing computational models for signal peptide prediction Uncovering mitochondrial-ER communication mechanisms He has supervised PhD theses (e.g., Paul Carlson) and contributed to over 39 research outputs. His work bridges structural biology, computational modeling, and translational pharmacology, with applications in tumor biology and neurodegenerative disease research.

Stefano Martinianiمشاهده پروفایل

استادیار

• Computational and Statistical Physics
• Materials Science
• Artificial Intelligence for Science
• +۵ مورد دیگر

Stefano Martiniani is an Assistant Professor of Physics, Chemistry, Mathematics, and Neuroscience at New York University, affiliated with the Center for Soft Matter Research and the Simons Center for Computational Physical Chemistry. His interdisciplinary research explores computational physics of complex systems, including neural circuit theories, non-equilibrium statistical mechanics, and AI-driven materials discovery. He has pioneered methods for analyzing high-dimensional energy landscapes and received prestigious awards like the NSF CAREER Award (2024) and IUPAP Early Career Prize (2023). Education: PhD in Physics (2017), University of Cambridge MPhil in Physics (2013), University of Cambridge BSc in Physics (2012), Imperial College London Research Interests: His work bridges statistical physics and artificial intelligence, focusing on: Engineering disordered materials with tailored spectral properties Quantifying entropy production in active matter Developing open science frameworks like ColabFit for machine learning interatomic potentials Neural circuit models for cortical communication Grants & Collaborations: Funded by NSF, NIH, Chan Zuckerberg Initiative, and Simons Foundation. Leads interdisciplinary teams in computational physics, AI, and materials science. Labs/Initiatives: Core member of NYU's Center for Soft Matter Research; develops software tools like FReSCo and KLIFF-Torch for computational materials science.

Aurora Martinezمشاهده پروفایل

استاد

• Structural Biology
• Drug Discovery
• Neurometabolic Disorders
• +۷ مورد دیگر

Aurora Martinez is a Professor in the Department of Biomedicine at the University of Bergen, Faculty of Medicine. She leads the Biorecognition research group, focusing on the structural and functional aspects of biomolecules in neurometabolic disorders such as phenylketonuria (PKU) and dopamine synthesis defects. She is also a partner in the KG Jebsen Centre for Neuropsychiatric Disorders and a Toppforsk-funded project on the Arc protein, a master regulator of synaptic plasticity. Position: Professor Institution: University of Bergen Department: Department of Biomedicine Research Group: Biorecognition Email: aurora.martinez@uib.no Her research integrates structural biology, molecular recognition, and drug discovery to develop therapeutic strategies for genetic and neurodegenerative diseases. Key areas include tyrosine hydroxylase regulation, mitochondrial dysfunction in dopaminergic cells, and neurotransmitter transport mechanisms. She employs biochemical, cellular, and computational approaches to understand disease mechanisms and identify novel therapeutics. The recent publications (2023–2025) reflect a strong trend toward understanding dopamine-related pathways, protein stabilization, and therapeutic interventions in Parkinsonism and related disorders. Themes include chaperone-mediated protein stabilization, high-throughput screening for VMAT2 modulators, and computational tools for drug discovery. The work combines experimental validation with translational applications in neurodegenerative models. She has supervised multiple Master’s students, including Md. Ekhtear Mahmud, Sofie Breisnes Wormdahl, and Kristine Kippersund Brokstad, indicating active mentorship and training roles. Her involvement in large-scale collaborative projects highlights leadership and interdisciplinary engagement. While no specific awards are listed, her participation in prestigious programs like Toppforsk and the KG Jebsen Centre underscores recognition and funding success. She has no listed grants explicitly, but project affiliations suggest competitive funding support. Her research group maintains strong technical capabilities in protein analysis, cellular screening, and structural modeling. The Martinez Lab is actively involved in both fundamental and applied research, with future directions likely to expand into gene therapy, precision medicine for metabolic disorders, and neuroprotective strategies.

• Biomedical Imaging
• Neurosciences
• Molecular Imaging
• +۶ مورد دیگر

Professor Mark Lythgoe is a distinguished academic at University College London (UCL), where he serves as Professor of Biomedical Imaging in the Department of Imaging within the Faculty of Medical Sciences. He is the Founder and Director of the Centre for Advanced Biomedical Imaging (CABI) at UCL, a multidisciplinary research center hosting 12 state-of-the-art imaging modalities and 50 researchers. Additionally, he is Co-Director of the UCL Department of Imaging and Director of Biomedical Imaging Research at the Francis Crick Institute. Mark Lythgoe earned his Doctor of Philosophy from University College London in 1999 and his Master of Science from the University of Surrey in 1993. Professor Lythgoe has a long-standing track record in the development and application of biomedical imaging techniques, with research spanning from fundamental imaging science to clinical applications. His work focuses on advancing imaging technologies for biomedical research and clinical practice, with particular emphasis on neuroimaging, molecular imaging, and the application of imaging to understand neurological disorders and cancer. He has translated his research findings into clinical radiological practice and established training programs in biomedical imaging. His extensive publication record demonstrates consistent innovation across imaging modalities, with recent work increasingly focused on the glymphatic system in neurological disorders, advanced tumor imaging techniques, and the development of novel imaging technologies for both preclinical and clinical applications. His research bridges engineering, physics, biology, and clinical medicine to solve complex biomedical challenges. Professor Lythgoe's significant contributions to the field have been recognized with numerous prestigious awards: IET Achievement Medal (2023) - for major and distinguished contribution in Medical Imaging Royal Society of Medicine Ellison-Cliffe Award (2021) - for contribution of fundamental science to the advancement of medicine Davies Medal from the Royal Photographic Society (2013) - for significant contribution to imaging science Alumni Achievement Award from the University of Salford Neuroscience Prize for Public Understanding from the British Neuroscience Association Dorothy Hodgkin Award Biosciences Federation Science Communication Award Fellow of the British Science Association Professor Lythgoe has secured substantial research funding, with £45 million awarded for his collaborative imaging research program. He is deeply committed to training the next generation of imaging scientists, serving as Co-Director of the MSc in Advanced Biomedical Imaging and Co-Founder of the UCL Centre for Doctoral Training in Medical Imaging. His public engagement efforts include directing the Cheltenham Science Festival, which has become one of the largest science festivals in the world. As Director of the Centre for Advanced Biomedical Imaging, Professor Lythgoe leads a vibrant research team of 50 researchers working across 12 state-of-the-art imaging modalities. His center fosters interdisciplinary collaboration between engineers, physicists, biologists, and clinicians to develop and apply cutting-edge imaging technologies. He has published over 300 papers including publications in Nature, Nature Photonics, Nature Medicine and The Lancet, demonstrating the high impact of his research across multiple disciplines.

• Genetics
• Cancer Predisposition
• Overgrowth Disorders
• +۷ مورد دیگر

Julian Antonio Martinez-Agosto is an Associate Professor at the UCLA School of Medicine with appointments in the Department of Human Genetics, Pediatrics, and Psychiatry and Biobehavioral Sciences. Board-certified in Medical Genetics, he has served on the UCLA faculty since 2007 after completing his MD/PhD at Yale University and pediatric training at Mattel Children's Hospital UCLA. His research focuses on novel growth regulatory pathways in progenitor and stem cell maintenance, particularly studying human growth disorders with cancer predisposition. Yale University: MD/PhD in Medicine/Neuroscience (2000) UCLA: Pediatric Residency and Medical Genetics Training Postdoctoral Fellow: Laboratory of Utpal Banerjee at UCLA Dr. Martinez-Agosto's research spans genetics, developmental biology, and neurogenetics with specific emphasis on overgrowth disorders, cancer predisposition syndromes, and autism spectrum disorders. His laboratory investigates molecular pathways including PTEN, mTOR, and other growth regulatory mechanisms using both human clinical studies and Drosophila models. His clinical practice focuses on genetic syndromes leading to overgrowth, vascular malformations, and cancer predisposition. His recent publications reveal strong trends in autism genomics, PTEN-related disorders, neurodevelopmental conditions, and molecular mechanisms of growth regulation. The research demonstrates interdisciplinary collaboration across genetics, neurology, and pediatrics with emphasis on translational applications. Cell Press 2021 Faces of Cell Pediatric Department Outstanding Research Award David W. Smith Pediatric Trainee Research Award Dr. Martinez-Agosto serves as Principal or Co-Principal Investigator on multiple NIH-funded research projects including studies on PTEN-associated autism, undiagnosed disorders, and Drosophila hematopoietic stem cell niches. His laboratory has trained numerous researchers in the field of medical genetics and developmental biology. His research is conducted through the Martinez Lab, which maintains active collaborations with multiple research groups at UCLA and other institutions, focusing on translational approaches to understanding genetic growth disorders.

Andy Sarlesمشاهده پروفایل

دانشیار

• biomaterials engineering
• biomimetic membranes
• neuromorphic computing
• +۳ مورد دیگر

Andy Sarles is the James Conklin Fellow and Associate Professor in the Department of Mechanical, Aerospace and Biomedical Engineering at the University of Tennessee, Knoxville. He leads the Sarles Group, which specializes in bio-inspired materials and interfaces, focusing on biomembranes and neuromorphic computing. He holds a Ph.D. (2010) and M.S. (2006) from Virginia Tech and a B.S. (2004) from the University of Tennessee, Knoxville. His research explores biomimetic membranes for sensing, energy conversion, and actuation, alongside nanomaterial interactions and soft, reconfigurable materials. Key projects include droplet interface bilayers (DIBs) for neuromorphic systems and mechanotransduction studies. Rewarded with the NSF CAREER Award (2018), Tickle College Professional Promise in Research (2018), and UT Research Foundation Innovation Award (2016), his work bridges engineering and biology. He advises Ph.D. and M.S. students like Subhadeep Koner, Colin Basham, and Joseph Tawfik, advancing interdisciplinary research in adaptive materials. The Sarles Group’s lab develops cell-inspired materials for neuromorphic computing, with applications in smart sensors and bioelectronic interfaces. Recent breakthroughs include memristive biomembranes mimicking synaptic plasticity, published in ACS Nano and other journals.

• Glaucoma Research
• Visual Field Testing
• Age-Related Macular Degeneration
• +۷ مورد دیگر

Professor David P. Crabb is a leading researcher in the Department of Optometry and Visual Science within the School of Health Sciences at City, University of London. With over 180 publications spanning from 2010 to 2025, his work has significantly contributed to the fields of glaucoma research, age-related macular degeneration, and visual field testing methodologies. He is particularly known for his involvement in the MACUSTAR study, a major international research initiative focused on developing clinical endpoints for intermediate age-related macular degeneration. Crabb's research interests span a wide range of ophthalmic topics with particular emphasis on visual field progression in glaucoma, structure-function relationships in retinal diseases, and patient-centered outcomes in eye care. His work has consistently bridged the gap between clinical practice and research methodology, developing novel approaches to visual field testing and analysis. He has made substantial contributions to understanding eye movements in patients with visual field loss and their implications for daily functioning. His recent publications (2024-2025) demonstrate continued leadership in the field, with significant contributions to MACUSTAR study reports, glaucoma progression analysis, and patient-centered research in geographic atrophy. These works showcase his dual focus on technical innovation in visual assessment and the practical implications for patient care and quality of life. Professor Crabb has collaborated extensively with international research groups across Europe and has contributed to major multicenter studies including the United Kingdom Glaucoma Treatment Study (UKGTS) and the LiGHT trial. His work frequently appears in top ophthalmology journals including Ophthalmology, Investigative Ophthalmology & Visual Science, and American Journal of Ophthalmology. His research methodology often combines traditional clinical approaches with advanced data analysis techniques, including machine learning applications for predicting visual field progression and optimizing testing protocols. This interdisciplinary approach has positioned him as a key contributor to evidence-based practice in ophthalmology.

• Proteomics
• Metabolomics
• Plant-Microbe Interactions
• +۳ مورد دیگر

Prof. Dr. Karsten Niehaus serves as Head of the Proteome and Metabolome Research Group at the Center for Biotechnology (CeBiTec) and Faculty of Biology, University of Bielefeld. His research focuses on proteomics and metabolomics applications in plant-microbe interactions, bacterial stress responses, and disease model systems. His laboratory employs advanced mass spectrometry imaging and cell phenotyping technologies to investigate molecular responses in crops like sugar beet and grapevines under abiotic stress conditions, as well as in cancer models where differentiation therapy impacts tumor malignancy. The group also explores microbial biotechnology through Xanthomonas campestris studies on xanthan production and stress adaptation. Selected publications highlight innovations in 3D microfluidics for biomarker detection and bioinformatics platforms like MetHoS for metabolomics data analysis. His work appears in journals covering Frontiers in Plant Science , Scientific Reports , and Journal of Experimental Botany . Contact: kniehaus@cebitec.uni-bielefeld.de | Office: UHG W7-117

• Biostatistics
• Neuroimaging Analysis
• Causal Inference
• +۳ مورد دیگر

Brian Caffo is a Professor in the Department of Biostatistics at the Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, with an active research profile evidenced by 2024-2025 publications and GitHub contributions. He is a key contributor to Neuroconductor (an R platform for medical imaging analysis) and the Acute to Chronic Pain Signatures (A2CPS) project, while maintaining significant educational impact through Coursera data science courses and open-source textbooks. His research spans biostatistics, neuroimaging analysis, and causal inference methodology, with emphasis on functional MRI data, multi-omics integration, and machine learning applications in public health. Current work focuses on advanced neural architectures for brain imaging, causal mediation in autism research, and biomarker discovery for chronic pain and neurodegenerative diseases. Analysis of his 15 most recent publications reveals dominant themes in transformer-based neuroimaging analysis (28%), causal inference applications (27%), and multi-omics/pain signature research (20%). His work consistently bridges statistical methodology with clinical applications in HIV prevention, autism spectrum disorders, and long COVID prediction through large collaborative projects like the National COVID Cohort Collaborative. Dr. Caffo leads the JHU Data Science Lab and contributes to multiple interdisciplinary initiatives including shell MEA development for neural organoids and DREAM-02 HIV microbicide trials. His GitHub profile shows active maintenance of educational repositories like LittleInferenceBook and regmodsbook, supporting widespread adoption of data science methods in biomedical research.

• Cardiac Electrophysiology
• Cardiac Arrhythmias
• Lysosomal Calcium Signaling
• +۵ مورد دیگر

Associate Professor Rebecca Burton is a cardiac electrophysiologist in the Department of Pharmacology at the University of Oxford's Medical Sciences Division. Since completing her DPhil in 2006, she has led research on cardiac arrhythmias with focus on lysosomal calcium signaling and hydroxychloroquine's effects on heart rhythm. Her group of approximately 10 researchers employs novel imaging methods and traditional pharmacology techniques to study cardiac function. Her research interests center on cardiac arrhythmia mechanisms, particularly the role of lysosomal calcium stores in atrial fibrillation. She investigates cAMP-Ca 2+ cross talk in atrial nanodomains, IP3 receptor signaling , and acidic organelle function in cardiomyocytes. Her work bridges basic science with translational applications through collaborations with clinicians across disciplines. Her 15 most recent publications (2022-2025) demonstrate consistent focus on lysosomal calcium signaling in cardiac rhythm regulation, with particular emphasis on atrial-specific mechanisms. Key themes include compartmentalized cAMP signaling, NAADP-mediated calcium release, and the role of endolysosomal networks in atrial fibrillation pathophysiology. Scientific recognition includes: Winston Churchill Medal for contributions to Science and Technology (2015-2016) Sir Henry Dale Fellowship supporting her ambitious interdisciplinary research Beyond research, Burton serves in teaching roles including examination setting and marking, provides pastoral care at her college, and actively engages in public outreach through events like the Science Museum Lates. She has advocated for improved career pathways for early-career researchers and greater equality of opportunity in academia. Her laboratory specializes in advanced cardiac optical mapping, lysosomal calcium imaging, and multi-disciplinary approaches to studying the neuro-cardiac axis, with particular focus on how sympathetic neuronal activity affects cardiac conduction and arrhythmia susceptibility.

• Neurobiology
• Cell Biology
• Biomedical Imaging
• +۳ مورد دیگر

Dr. Simone Mortal is a Postdoctoral Researcher at the Institute of Photonic Sciences (ICFO), part of the SLN - Team Loza research group. They hold a PhD in Neurobiology from the International School for Advanced Studies (Italy). Their work focuses on advanced imaging techniques and cellular neurobiology, with specialties in super-resolution imaging, multiphoton microscopy, and confocal microscopy. Research interests include mechanisms of glioblastoma replication, neuronal mechanotransduction, microtubule dynamics in neurodegenerative diseases, and cytoskeletal roles in neuronal development. Dr. Mortal's research bridges biophysics and neuroscience, addressing fundamental questions about cellular signaling and disease mechanisms. They are based in Barcelona, Spain, and can be reached at Simone.Mortal@icfo.eu. Education: PhD in Neurobiology (International School for Advanced Studies, Italy). Research Themes: Investigating calcium signaling in neurodegeneration, mechanosensitive pathways in neurons, and actin dynamics during neuronal maturation. Their studies employ cutting-edge microscopy techniques to visualize cellular processes at high resolution, with a focus on glioma-derived exosome effects, growth cone mechanics, and cytoskeletal scaffolding in neural development. Labs/Teams: Active member of the SLN - Team Loza group at ICFO, specializing in neurobiophotonics and cellular imaging.