معرفی
Dr. Zeynep Erson Omay serves as an Assistant Professor in the Department of Neurosurgery and Biomedical Informatics & Data Science at Yale School of Medicine. Her work bridges computational biology with neurosurgical oncology, focusing on precision medicine applications for brain tumors, with particular emphasis on understanding tumor heterogeneity and molecular mechanisms of CNS tumors.
Dr. Erson Omay's educational background includes:
- PhD in Computer Science from Case Western Reserve University (2011)
- MS in Computer Science from Bilkent University (2005)
- BS in Computer Science from Bilkent University (2003)
Her research focuses on computational analysis of multi-omic datasets to understand tumor heterogeneity, particularly in central nervous system tumors. Dr. Erson Omay specializes in genomic, transcriptomic, and epigenetic profiling of brain tumors, with emphasis on meningiomas, glioblastomas, and rare CNS tumor subtypes. She leads the Erson Lab, which develops bioinformatics approaches to study large datasets and reveal molecular mechanisms in tumor formation, progression, and clinical outlier subgroups. Her work in precision medicine aims to decipher the molecular architecture of individual tumors to guide personalized treatment approaches, with significant contributions to understanding tumor ecosystems and evolutionary patterns in brain cancers.
Dr. Erson Omay's scientific contributions span neuro-oncology, computational biology, and precision medicine, with a strong emphasis on translating genomic findings into clinical applications. Her publications demonstrate consistent innovation in applying computational methods to complex neurosurgical problems, with particular focus on tumor heterogeneity, molecular classification, and racial disparities in tumor genomics.
Her notable scientific awards include:
- 10x Genomics 2021 Pilot Award (2022)
- Mission Bio Tapestri Grant (2022)
- Case Western Reserve University, Research ShowCASE-Best Poster Award (2007)
Dr. Erson Omay actively mentors students and researchers at various levels, including undergraduate students, graduate students, postdocs, and postgraduate associates. She collaborates extensively within Yale's neurosurgery department and across disciplines to advance computational approaches to brain tumor research. Her work is supported by various grants that enable the development of novel bioinformatics platforms for tumor genomic characterization.
She leads the Erson Lab, which focuses on three major research areas: Tumor Ecosystem (studying interactions among tumor and immune cells), Tumor Evolution and Heterogeneity (understanding temporal and spatial tumor evolution), and Precision Medicine (applying genomic techniques to personalize brain tumor treatment). The lab employs diverse omics technologies to explore brain tumor biology and develop computational methods for precision medicine applications.
