Brendan E. Depue, Ph.D., is an Associate Professor and Endowed Chair of Behavioral Brain Imaging and Neurobiology in the Department of Psychological and Brain Sciences at the University of Louisville. He also serves as an Affiliate Assistant Professor in the Department of Anatomical Sciences and Neurobiology. His research focuses on the neuroanatomical substrates of inhibitory and cognitive control, particularly within the prefrontal cortex (PFC), using neuroimaging techniques such as fMRI and structural MRI. Depue’s work explores emotional memory regulation, PTSD, anxiety, and decision-making processes. Depue earned his Ph.D. in 2009 from the University of Colorado at Boulder. His lab, the (N)euro(I)maging (L)aboratory of (C)ognitive, (A)ffective and (M)otoric Processes (NILCAMP), investigates how brain networks regulate cognitive, emotional, and motor functions. His research has identified key neural correlates of memory suppression in PTSD, structural covariance differences in depression, and gender-specific neural connectivity during emotion regulation. Recent publications highlight his exploration of fear learning mechanisms, neural networks underlying interoceptive awareness, and the translational potential of the bed nucleus of the stria terminalis in anxiety research. Depue’s interdisciplinary approach integrates clinical neuroscience with advanced imaging methodologies to address complex mental health challenges.









