Nervous System Evolution Professors and Supervisors

Paschalis Kratsiosمشاهده پروفایل

دانشیار

University of ChicagoUnited States

Paschalis Kratsios is an Associate Professor in the Department of Neurobiology at the University of Chicago's Biological Sciences Division. His research program investigates gene regulatory mechanisms underlying motor neuron development and dysfunction, with implications for neurodegenerative diseases like ALS. Dr. Kratsios employs C. elegans and mouse models alongside cutting-edge genomic techniques including CRISPR editing and ATAC-seq. His academic training includes a Ph.D. in Developmental Biology from the European Molecular Biology Laboratory (EMBL, 2009) and postdoctoral training in Developmental Neurobiology at Columbia University (completed 2016). Research interests center on: Motor neuron specification via transcription factor networks Chromatin dynamics in neuronal identity maintenance Evolutionarily conserved mechanisms from C. elegans to mammals Neurodegenerative pathogenesis in ALS and spinal muscular atrophy Recent publications (2021-2025) demonstrate a strong focus on Hox gene functions, neuronal identity maintenance, and CRISPR-based methodologies, with work published in Nature Communications , Cell Reports , and eLife . Awards and honors: NIH K99/R00 Pathway to Independence Award (2013-2018) Whitehall Foundation Award for Neurobiology (2017-2019) Dr. Kratsios leads multiple NIH-funded projects as Principal Investigator, including R01 grants focused on motor neuron terminal identity mechanisms. His lab emphasizes cross-species validation and genomic approaches to decode cis-regulatory elements governing neural development. The Kratsios Lab (http://kratsioslab.uchicago.edu) integrates genetics, genomics, and behavioral assays to study neurodevelopmental and neurodegenerative disorders, with active collaborations across neurobiology and genomics fields.

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Kartik Venkatachalamمشاهده پروفایل

استاد

The University of Texas Health Science Center at HoustonUnited States

Kartik Venkatachalam, PhD, is a Professor at The University of Texas Health Science Center at Houston. His research program takes a multi-tiered approach to understanding nervous system function, focusing on signal transduction mechanisms, synaptic development, vesicular trafficking, and decision-making processes in neural circuits. Research Interests: Identification of novel components regulating synaptic growth and connectivity ('synaptic developtome') Molecular mechanisms of endosomal/lysosomal trafficking relevant to neurodegeneration and cancer Neuronal network dynamics underlying decision-making in adult Drosophila TRP channel function in endolysosomal pathways and cellular homeostasis His publications demonstrate consistent focus on ion channel biology (particularly TRP channels), vesicular trafficking mechanisms, synaptic regulation, and Drosophila neurobiology. Recent work emphasizes the connection between lysosomal function, nutrient sensing (mTORC1 pathway), and neurodevelopmental processes.

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Björn Kullمشاهده پروفایل

استاد

Karolinska InstitutetSweden

Björn Kull serves as Head of Department for Joint Operational Support within the Department for Research Support and External Relations at Karolinska Institutet, one of Europe's foremost medical universities. He earned his Doctoral Degree of Medicine from Karolinska Institutet's Department of Physiology and Pharmacology in 2000, establishing a strong foundation for his career in academic research and administration. Professor Kull's research expertise spans pharmaceutical sciences, pharmacology, toxicology, and neurosciences, with a particular focus on adenosine receptor pharmacology and its interactions with dopamine signaling pathways. His work has significantly contributed to understanding receptor signaling mechanisms in the central nervous system. Analysis of his publication record from 1996-2012 reveals a consistent focus on adenosine receptors, particularly the A2A subtype, and their interactions with dopamine receptors. His research trajectory shows progression from basic receptor characterization to more complex studies of receptor interactions and signaling pathways, demonstrating increasing sophistication in experimental approaches over time. While no specific scientific awards are mentioned in the available information, Professor Kull's publication record in high-impact journals such as Nature Biotechnology, Molecular Pharmacology, and Neuroscience indicates recognition within his field. His transition from active research to research administration reflects a career evolution common among senior academics who apply their scientific expertise to institutional leadership. In his current administrative role, Professor Kull oversees research support operations at Karolinska Institutet, leveraging his deep understanding of the research process to facilitate scientific discovery across the institution. His leadership contributes to maintaining Karolinska Institutet's position at the forefront of medical research.

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Christian J. Hartmannمشاهده پروفایل

دانشیار بالینی

University DuesseldorfGermany

PD Dr. Christian J. Hartmann serves as a Clinical Associate Professor and senior physician at the Department of Neurology, Faculty of Medicine, Heinrich Heine University Düsseldorf. Renowned for his Medical Faculty Teaching Award-winning instruction in the 'Head and Nervous System' module, he embodies a student-centered educational philosophy grounded in clinical realism and innovative pedagogy. His expertise spans Clinical Neurology with specialized focus on Movement Disorders (including Wilson's disease management), EEG Diagnostics , and Deep Brain Stimulation applications. Educational innovation defines his methodology—most notably through the MIDNIGHT differential diagnosis framework (Metabolic, Inflammatory, Degenerative/Traumatic, Neoplastic, Ischemic, Genetic, Hemorrhagic, Toxic) and student-generated mnemonic techniques that transform complex neurological concepts into memorable clinical tools. Dr. Hartmann's teaching accolades include: Medical Faculty's Teaching Award for exceptional clinical instruction Consistent student nominations citing his role-model status and outpatient clinic mentorship Recognition for bridging theoretical knowledge with practical neurological assessment Through pandemic-era virtual teaching adaptation, he demonstrated commitment to educational evolution while maintaining core bedside teaching values. His vision prioritizes technology-enhanced learning platforms —particularly for EEG diagnostics and deep brain stimulation programming—that complement hands-on clinical training without replacing the irreplaceable human element of neurological examination.

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David Freisمشاهده پروفایل

پژوهشگر

University of AugsburgGermany

Dr. David Freis serves as Akademischer Rat (Academic Counselor) at the University of Augsburg's Faculty of Medicine, where he leads the Department of History of Medicine within the Institute for Ethics and History of Health in Society. His scholarly work bridges historical analysis with contemporary ethical considerations in medicine, making significant contributions to the field of Medical Humanities. His research focuses on multiple interconnected areas including contemporary history of medicine, medical future concepts and utopias, and the history of medical technologies and media in the 20th century. He has particular expertise in digitalization and telemedicine history, examining how communication technologies have transformed medical practice. His work also explores the interfaces between medical, media, and technology history, the history of medical science since the 19th century, and the history of psychiatry and psychotherapy with special attention to Jewish contributions. Analysis of Dr. Freis's recent publications (2020-2025) reveals a consistent thematic focus on how medical institutions and technologies have envisioned and shaped healthcare futures. His work demonstrates how historical perspectives on medical utopias and technological innovations provide crucial context for understanding current healthcare challenges and developments, particularly in German contexts. Förderpreis des Fachverbands Medizingeschichte (2019) William Bynum Prize of the Journal Medical History (2017) Nachwuchspreis 2015/2016 of the German Society for the History of Neurology (2017) Promotionsstipendium des Europäischen Hochschulinstituts, Florenz (2014-2015) Before joining the University of Augsburg, Dr. Freis was a research assistant at the University of Münster (2015-2021). He completed his doctoral studies at the European University Institute in Florence after earning his M.A. with distinction in history, political science, and gender studies from Ruhr University Bochum. He is actively engaged with professional organizations, serving on the board of the Society for the History of Sciences, Medicine and Technology (GWMT) and participating in the European Association for the History of Medicine and Health.

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Ollivier Hyrienمشاهده پروفایل

استاد

Fred Hutchinson Cancer CenterUnited States

Ollivier Hyrien is a Professor in the Biostatistics, Bioinformatics and Epidemiology Program within the Vaccine and Infectious Disease Division, and also a Professor in the Herbold Computational Biology Program within the Public Health Sciences Division at the Fred Hutchinson Cancer Center. He is additionally a Member of the Translational Data Science Integrated Research Center (TDS IRC) at Fred Hutch. Dr. Hyrien is a biostatistician who applies advanced technologies such as machine learning and dynamic modeling to address problems in laboratory experiments and clinical studies. His research focuses on statistical methods for flow cytometry, single-cell sequencing and other bioassays. He holds a PhD in Statistics from the University of Rennes 1, Rennes, France (2001). His research interests include: Statistical methods for bioassays (e.g., flow cytometry, sequencing) Machine learning (e.g., nonparametric clustering and classification) Dynamic modeling (e.g., B-cell repertoire) Dr. Hyrien leads the Hyrien Lab, which specializes in developing and applying statistical methods, computational tools, and mathematical models to study the immune system and other complex biological systems, such as the microbiome, the hematopoietic system, and the central nervous system, using high-dimensional, high-throughput data. A core focus of his current research is supporting the development of vaccines and passive immunization strategies against diseases caused by pathogens such as HIV, malaria, SARS-CoV-2, herpes simplex virus, as well as treatments against cancer. One exciting area of his research is the study of the evolution of the B-cell repertoire, involving the use of machine learning and statistical tools as well as stochastic processes to quantify and predict how somatic hypermutation accumulates over time in immunoglobulin genes. His recent publications demonstrate a strong focus on HIV vaccine development, statistical methods in immunology, and mathematical modeling of immune responses. His work spans across multiple disciplines including biostatistics, immunology, virology, and computational biology, with significant contributions to understanding antibody development and vaccine efficacy. Dr. Hyrien is highly collaborative, working closely with numerous research groups across various institutions to advance the understanding of complex biological systems and their interactions with human health and treatments.

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Joelle Payne Straehlaمشاهده پروفایل

استادیار

Fred Hutchinson Cancer CenterUnited States

Dr. Joelle Payne Straehla is an Assistant Professor of Pediatrics at the University of Washington School of Medicine and an Adjunct Assistant Professor of Bioengineering. She serves as a principal investigator at Seattle Children's Research Institute and as a pediatric oncologist in the Brain Tumor Program at Seattle Children's Hospital. Dr. Straehla is also a member of the Fred Hutch/University of Washington/Seattle Children's Cancer Consortium. Dr. Straehla received her MD from Northwestern University Feinberg School of Medicine and completed her pediatric residency at Seattle Children's Hospital/University of Washington. She further completed a fellowship in pediatric hematology/oncology at Dana-Farber/Boston Children's Cancer and Blood Disorders Center, where she gained additional training in biological and chemical engineering in the laboratory of Dr. Paula Hammond at Massachusetts Institute of Technology. Prior to joining Seattle Children's in 2024, she was an Instructor of Pediatrics at Harvard Medical School and a Charles W. (1955) and Jennifer C. Johnson Clinical Investigator at MIT's Koch Institute for Integrative Cancer Research. Dr. Straehla's research focuses on advancing drug delivery technologies for pediatric cancers, with a special interest in cancer nanomedicine. Her work operates at the intersection of nanotechnology and cancer biology, aiming to bridge the gap between innovative engineering tools and clinical practice. She leads the Straehla Lab, which is dedicated to designing new nanoparticle-based therapeutics, identifying biological regulators of nanoparticle drug delivery, improving delivery across challenging tissue barriers, and developing strategies to remodel the tumor microenvironment. Her research has significant implications for improving treatment of pediatric brain tumors and other difficult-to-treat childhood cancers. Dr. Straehla's publication record demonstrates expertise in nanoparticle design, blood-brain barrier penetration, and targeted cancer therapies. Her work includes developing predictive microfluidic models of glioblastoma, identifying biomarkers for nanoparticle delivery (particularly SLC46A3), and engineering layer-by-layer nanoparticles for improved brain tumor targeting. Her research combines high-throughput screening, genomic analysis, and translational approaches to accelerate the development of nanomedicine for pediatric cancer patients. Among her notable recognitions is the Charles W. (1955) and Jennifer C. Johnson Clinical Investigator position at MIT's Koch Institute for Integrative Cancer Research. Her work has been published in high-impact journals including Science, Proceedings of the National Academy of Sciences, and ACS Nano. As a clinician, Dr. Straehla cares for children with brain and spinal cord tumors and is involved in local and national consortia focused on improving brain tumor drug delivery through collaborative research. She is committed to harnessing cutting-edge engineering methods to improve outcomes for children with cancer while minimizing side effects to the developing brain. The Straehla Lab operates at the Ben Towne Center for Childhood Cancer and Blood Disorders Research and includes a diverse team of researchers working on various aspects of nanomedicine and drug delivery. Current projects include unlocking the drivers of nanoparticle delivery, engineering combination nanomedicines, and developing precision drug carriers for the central nervous system.

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Mina Hosseinipourمشاهده پروفایل

استاد

University of North Carolina at Chapel HillUnited States

HIV disease management in developing countries
HIV prevention
Antiretroviral therapy
+۶ مورد دیگر

Mina Hosseinipour, MD, MPH is a Professor of Medicine at the University of North Carolina at Chapel Hill School of Medicine, where she serves as Scientific Director of UNC Project-Malawi. Her work focuses on infectious diseases research with a particular emphasis on global health initiatives in sub-Saharan Africa. She received her medical degree from Northwestern University Medical School and completed her MPH at the University of North Carolina at Chapel Hill, establishing a strong foundation in both clinical medicine and public health that informs her research approach. Dr. Hosseinipour's research interests center on HIV disease management in developing countries, including prevention strategies, interactions with endemic diseases, treatment of opportunistic infections and malignancies, and monitoring strategies for antiretroviral therapy. Her work has been instrumental in establishing antiretroviral therapy as a key HIV prevention strategy in resource-limited settings. She has led numerous large-scale clinical trials that have shaped global HIV treatment guidelines. Her recent publications demonstrate a consistent focus on improving HIV prevention and treatment in resource-limited settings, with particular attention to long-acting antiretrovirals, cryptococcal meningitis management, and tuberculosis treatment optimization. Her research spans clinical trials, epidemiological studies, and guideline development that directly impacts global health policy. As Scientific Director of UNC Project-Malawi, Dr. Hosseinipour oversees a major research initiative based at the Tidziwe Centre in Lilongwe, Malawi. This program represents a significant collaboration between UNC and Malawian institutions, focusing on clinical research that addresses the most pressing infectious disease challenges in the region. Her leadership extends to major international research consortia including the AIDS Clinical Trials Group, Tuberculosis Trials Consortium, and multiple HPTN studies. Through these collaborations, she has contributed to landmark studies that have transformed HIV prevention and treatment approaches worldwide, particularly in settings with limited healthcare resources.

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P. Frederick Sparlingمشاهده پروفایل

استاد

University of North Carolina at Chapel HillUnited States

P. Frederick Sparling, MD is a Professor of Medicine in the Division of Infectious Diseases at the University of North Carolina at Chapel Hill School of Medicine. His clinical and research work focuses on infectious diseases, particularly sexually transmitted infections. Dr. Sparling's research interests include general infectious diseases, sexually transmitted infections, emerging infections, and biodefense. His work has significantly contributed to our understanding of Neisseria gonorrhoeae, syphilis, and chlamydial infections, with research spanning several decades from the 1970s through the present day. His publication record shows consistent contributions to the field of infectious diseases, with recent work in 2024 on 'Beginnings' and earlier seminal works on antibiotic resistance in Neisseria gonorrhoeae, diagnosis of neurosyphilis, and the genetics of the gonococcus. His research has appeared in prestigious journals including the New England Journal of Medicine, Journal of the American Medical Association, and Clinical Infectious Diseases, demonstrating his expertise in bacterial pathogenesis, diagnostic methodologies, and treatment approaches for sexually transmitted infections. Dr. Sparling has maintained an active research profile for over 50 years, with publications spanning from 1965 to 2024. His work demonstrates a consistent focus on bacterial pathogens, particularly Neisseria species and Treponema pallidum (the causative agent of syphilis), with significant contributions to understanding antibiotic resistance mechanisms, diagnostic approaches, and bacterial survival strategies. His research has practical implications for clinical practice, as evidenced by publications on diagnostic algorithms for syphilis and new tools for neurosyphilis diagnosis. His work bridges basic science and clinical application, contributing to both theoretical understanding of bacterial pathogenesis and practical approaches to diagnosis and treatment.

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Nandini Hayesمشاهده پروفایل

دانشیار

Queen Mary University of LondonUnited Kingdom

Nandini Hayes is a Reader in Medical Sciences at the Centre for Medical Education, Institute of Health Sciences Education, Faculty of Medicine and Dentistry, Queen Mary University of London. She joined Barts and the London School of Medicine in 2016 after teaching positions at the University of East London, University of Roehampton, and University of Kent. Her academic roles include co-module lead for Fundamentals of Medicine (MBBS Year 1) and Practical Skills for Professionals II (CCFS course), Principle Internal Examiner for Year 2, and Joint Lead for Problem-Based Learning. Her educational background comprises a Medical Biochemistry degree from Royal Holloway College, University of London, and postgraduate research in neuronal cell biology at the University of Kent. Dr. Hayes' research demonstrates significant evolution across three decades: early work focused on neuronal cytoskeleton mechanics and spectrin-associated proteins, transitioning to cancer biology (neuregulin signaling in prostate/breast cancer, industrial protein production), and currently centering on medical education innovation. Her present work develops a 4-week transition program for medical/dental students and identifies post-pandemic teaching innovations, reflecting her adaptation to contemporary educational challenges. Analysis of her 15 publications (1991-2017) reveals a distinct trajectory from fundamental neuroscience to translational oncology and now educational scholarship. Current projects examine pandemic-driven adaptations across UK medical schools, emphasizing digital education and student support systems while maintaining rigorous assessment standards. Her scientific recognition includes: ASME Board Award (£20,000) for pandemic medical education research She actively supervises undergraduate research through BSc Module BIO603 and student-selected components while leading the MEDPRO supervision program. Her ASME-funded project investigates systemic changes in admissions, curriculum design, and widening participation across 40+ UK medical schools, positioning her at the forefront of educational reform. As a core member of the Centre for Medical Education, she drives innovation in the Faculty of Medicine and Dentistry through evidence-based teaching practices, particularly in post-pandemic educational recovery and student transition support systems.

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W.W.M. (Pim) Pijnappelمشاهده پروفایل

دانشیار

Erasmus University RotterdamNetherlands

W.W.M. (Pim) Pijnappel serves as Associate Professor in the Department of Pediatric Metabolic Diseases at Erasmus University Rotterdam and Head of Basal Research at the Center for Lysosomal and Metabolic Diseases, Erasmus MC Rotterdam, a position held since 2012. His academic credentials include: MSc in Medical Biology from Utrecht University, Netherlands PhD from Utrecht University, Netherlands (1996) Pijnappel's research integrates stem cell biology, genome engineering, and epigenetic mechanisms to address lysosomal storage disorders. His work specifically targets skeletal muscle, cartilage, and central nervous system pathologies in Pompe disease and Mucopolysaccharidoses (MPS), developing disease models and novel therapeutic approaches through genetic engineering. Publication analysis reveals a strategic research evolution from foundational molecular discoveries (epigenetic regulation, 2001; genome editing techniques, 2003) toward translational stem cell applications for rare diseases (2013). This trajectory demonstrates consistent high-impact contributions across molecular biology, regenerative medicine, and rare disease therapeutics. He directs the Molecular Stem Cell Biology of Lysosomal Storage Diseases research group, focusing on metabolic enzyme deficiencies that cause systemic accumulation of substrates and multi-organ damage, with emphasis on stem cell-based therapeutic development.

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Lars Heringمشاهده پروفایل

پژوهشگر

University of KasselGermany

Dr. Lars Hering is a Postdoctoral Researcher in the Department of Zoology at the University of Kassel, Germany. His research focuses on the evolutionary biology of Panarthropoda, with particular expertise in Onychophora (velvet worms) and Tardigrada (water bears). He collaborates with the Lund Vision Group at Lund University, Sweden, to investigate visual system evolution across these phyla. His primary research interests include evolutionary biology, comparative genomics, visual system evolution, molecular evolution, and arthropod evolution. Dr. Hering employs molecular, anatomical, and electrophysiological methods to study opsin genes, neuropeptides, and other proteins that reveal evolutionary relationships between velvet worms, tardigrades, and arthropods. His work bridges molecular biology with comparative anatomy to understand the evolutionary origins of complex traits. Analysis of Dr. Hering's publication record from 2012-2025 reveals a consistent focus on evolutionary developmental biology, particularly examining how visual and nervous systems evolved in Panarthropoda. His research combines molecular techniques with comparative approaches across multiple phyla, demonstrating interdisciplinary expertise spanning genomics, neurobiology, and evolutionary theory. Key themes include the evolution of opsins for vision, neuropeptide signaling systems, and structural proteins across evolutionary time. Preis für das beste Poster der Fachgruppe 'Zoologische Systematik' Dr. Hering has presented his research at numerous national and international conferences including the Deutsche Zoologische Gesellschaft meetings and BioSyst.EU conferences. His work receives financial support through various research grants that enable his comparative studies of Panarthropod evolution. He is actively involved in collaborative research projects examining the molecular basis of evolutionary innovations.

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Yoojin J. Choiمشاهده پروفایل

استاد

Point Loma Nazarene UniversityUnited States

Cell Biology
Neurobiology
Neuroscience
+۴ مورد دیگر

Yoojin J. Choi, Ph.D., serves as Professor of Biology at Point Loma Nazarene University (PLNU), joining the institution in 2022 after accumulating 15 years of diverse teaching experience. Previously, she held faculty positions at North Park University (2014-2022), California Baptist University, Korea University, and Seoul National University, with her academic journey beginning at Phillips Exeter Academy. Her educational background includes: Ph.D. in Neurobiology from Harvard University B.S. in Biological Sciences from the University of California, Irvine Dr. Choi's research integrates cell biology and neurobiology , particularly through studies of developing neurons and Chlamydomonas reinhardtii flagellar proteins. She actively incorporates faith-science dialogue into her scholarship, emphasizing student-centered and collaborative learning environments that extend from classroom instruction to undergraduate research mentorship. Her publication trajectory reveals an evolution from foundational neurodevelopmental research (2001-2009) toward contemporary scholarship in science education and faith integration (2014-2021), demonstrating consistent engagement with both scientific rigor and pedagogical innovation. Recognition for her contributions includes: 2024 Excellence in Teaching Award Dr. Choi has mentored student researchers since 2015 through PLNU's Summer Research Program and previous institutions, while presenting extensively at conferences including the Society for Neuroscience and National Science Teachers Association. Her professional engagement spans the Partnership for Undergraduate Life Science Education and the Lilly Fellows Program, reflecting commitment to both scientific advancement and educational community building. At PLNU, she directs a cell biology research laboratory focused on undergraduate participation and maintains active membership in the American Scientific Affiliation and Society for College Science Teachers, fostering interdisciplinary connections between scientific inquiry and broader intellectual frameworks.

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Kelly Monkمشاهده پروفایل

استاد پژوهشی

Oregon Health & Science UniversityUnited States

Kelly Monk is a senior scientist and co-director of the Vollum Institute at Oregon Health & Science University (OHSU), where she also directs the Vollum/OHSU Neuroscience Graduate Program. Her research focuses on glial cell biology and myelin dynamics in the nervous system using zebrafish and mouse models. Her educational background includes: B.S. in Biochemistry from Elmira College (2001) Ph.D. in Cell Biology from the University of Cincinnati (2006) Dr. Monk's research investigates how glial cells form, maintain, and repair myelin sheaths through neuron-glial and glial-glial interactions. She addresses fundamental questions about axonal ensheathment, membrane spiraling, and signaling pathways in developmental myelination versus regenerative remyelination. Her work bridges molecular mechanisms with functional outcomes in nervous system development and disease. Analysis of her 15 most recent publications reveals a consistent focus on molecular regulators of myelination (e.g., Dock1, FBXW7, TMEM63A) across vertebrate models. Her research spans from basic glial cell biology to translational applications for demyelinating disorders like multiple sclerosis, with increasing emphasis on calcium signaling, receptor function, and drug screening approaches. Her significant contributions have been recognized through prestigious awards: NIH BIRCWH Scholar Award (2012) Washington University Outstanding Faculty Mentor Award (2015) ASCB Emerging Leader Prize Finalist (2015) Washington University Distinguished Faculty Award (2016) National MS Society Harry Weaver Scholar Award (2016) As co-director of the Vollum Institute and leader of the Monk lab, she oversees a multidisciplinary team employing advanced genetic, imaging, and biochemical approaches to study glial cell development. Her lab's work on Schwann cells, oligodendrocytes, and astrocytes provides critical insights into nervous system development, injury response, and potential therapeutic interventions for myelin disorders.

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