جست‌وجوی استاد و پژوهشگر

Boyd Moreau Koffmanمشاهده پروفایل

استاد

• Multiple Sclerosis
• Neuromuscular Disorders
• Neuroimmunology
• +۲ مورد دیگر

Boyd Moreau Koffman, M.D., Ph.D. is a Professor in the Department of Neurology at the University of Toledo's College of Medicine. His expertise focuses on Multiple Sclerosis and Neuromuscular Disorders , with a research emphasis on neuroimmunology and therapeutic development. Education : M.D. from George Washington University College of Medicine and Health Sciences (1990), Ph.D. in Biochemistry from the University of Maryland (1990) Training : Internship at George Washington University Hospital (1990-1991), Neurology Residency at Henry Ford Hospital (1991-1994), Fellowship in Neuromuscular Diseases at NIH (1994-1997) Dr. Koffman's research explores neuroimmunological mechanisms in autoimmune diseases like MS, with recent work targeting macrophages in experimental autoimmune encephalomyelitis. His publications span clinical studies on Guillain-Barre syndrome, West Nile virus complications, and genetic neurological conditions. Scientific recognition includes Alpha Omega Alpha Induction (2020), multiple listings in Best Doctors in America , and awards for teaching excellence. He serves as an AdHoc Reviewer for journals including Clinical Neurology and Neurosurgery and Muscle & Nerve . Contact: neurology@utoledo.edu | Academic Office: Suite 201, 2130 W. Central Ave., Toledo, OH 43606

• Diabetes
• Obesity
• Adipocyte Differentiation
• +۳ مورد دیگر

Robert Mcgehee Jr. is a Distinguished Professor of Pediatrics and Neonatology at the University of Arkansas for Medical Sciences (UAMS) College of Medicine, where he also serves as Dean of the Graduate School. He holds additional appointments as Associate Professor in the Department of Pathology and Department of Physiology and Cell Biology. As Associate Fellowship Director for Neonatal/Perinatal Medicine, he mentors pediatric fellows and oversees research training programs. He co-founded UAMS's Clinical & Translational Science training infrastructure and directed the Education Core of the Translational Research Institute. His NIH-funded research focuses on molecular mechanisms underlying diabetes, obesity, and metabolic syndrome. Key areas include: Adipocyte differentiation and retinoblastoma protein regulation Muscle-adipose tissue crosstalk in insulin resistance Inflammatory pathways in adipose tissue macrophages Pharmacological interventions (e.g., pioglitazone, omega-3 fatty acids) His publications demonstrate consistent focus on adipogenesis, insulin signaling, and inflammation across human, murine, and cell-line models. Recent work emphasizes human translational studies on adipose tissue extracellular matrix, thermogenic gene regulation, and educational methodologies in medical training. Major Grants: R25HL108825 (Co-I): Summer Undergraduate Research Program (2011-2026) UL1TR000039 (Co-I): Arkansas Clinical & Translational Research Center (2009-2016) R25GM083247 (Co-PI): Maximizing Student Development Program (2008-2024) R01DK071349 (PI): Mechanisms of Metabolic Syndrome in Obesity (2005-2015) He leads collaborative labs investigating adipose-muscle macrophage interactions using Transwell co-culture systems and human tissue samples.

Casey Giffordمشاهده پروفایل

استادیار

• Congenital Heart Disease
• Stem Cell Biology
• Epigenomics
• +۴ مورد دیگر

Casey Gifford is an Assistant Professor of Pediatrics - Cardiology and Genetics at Stanford University School of Medicine . They are actively involved in research and teaching, with affiliations to multiple institutes including the Bio-X , Cardiovascular Institute , and Institute for Stem Cell Biology and Regenerative Medicine . PhD in Stem Cell Biology and Epigenomics from Harvard Medical School (2013) Postdoctoral Fellowship in Heart Development at Gladstone Institutes, UCSF (2019) Their research focuses on genetic and epigenetic mechanisms in cardiovascular development and disease, particularly congenital heart defects and gene regulatory networks . They use human induced pluripotent stem cell (iPSC) models , single-cell multiomic analysis , and CRISPR technology to investigate molecular pathways in cardiac development, fibroblast activation, and stress response. Recent publications highlight work on: Interferon signaling in thymic epithelial cell differentiation Mitochondrial variant pathogenicity in multisystem dysfunction Gene network convergence in valvular interstitial cells Mitochondrial-Nuclear incompatibility in hybrid species Transcription factor interactions (ISL1-NKX2.5) in cardiomyocyte fate They mentor graduate students in Genetics , Pediatric Cardiology , and Stem Cell Biology programs, and lead courses including Advanced Genetics and Stem Cell Intensive . Their lab contributes to the GREGoR Consortium for rare disease genomics and uses single-cell datasets to explore regulatory mechanisms in cardiac and craniofacial development.

Gu Ja-hyeonمشاهده پروفایل

دانشیار

• Pharmacological Target Discovery
• Fatty Liver Disease Mechanisms
• Hippo Signaling Network Applications
• +۳ مورد دیگر

Gu Ja-hyeon is an Associate Professor at the College of Pharmacy, Seoul National University, specializing in pharmacology and molecular signaling mechanisms related to liver disease and metabolic regulation. His research focuses on pharmacological target discovery, Hippo signaling network applications, and the molecular basis of fatty liver disease progression. Education: B.S. (2010) and Ph.D. (2017) in Pharmacology from Seoul National University Career: Postdoctoral Fellow at UC San Diego (2017-2019), Assistant Professor at Catholic University of Korea (2019-2021), and current faculty at Seoul National University College of Pharmacy His work integrates: YAP/TAZ signaling in metabolic dysfunction-associated steatotic liver disease ER and mitochondrial stress pathways in organ injury GPCR signaling networks regulating liver fibrosis Hippo pathway applications in pharmacology Selected publications highlight his contributions to: ER stress-activated macrophage signaling (2024) Redox-regulated YAP/TAZ activation (2024) Primary cilium proteins in cell proliferation (2023) USP21 ablation effects on metabolic phenotypes (2021) His lab ( Koo Lab ) bridges basic science and translational medicine, with significant publications in Cell Death & Disease , Archives of Pharmacal Research , and FASEB Journal .

Ying H Shenمشاهده پروفایل

استاد

• Aortic aneurysms and dissections
• Diabetic vascular diseases
• Vascular biology and diseases
• +۲ مورد دیگر

Dr. Ying H Shen, M.D., Ph.D., is a Professor of Surgery at Baylor College of Medicine and serves as the Director of the Aortic Disease Research Laboratory. She is affiliated with the Division of Cardiothoracic Surgery and has joint affiliations with the Texas Heart Institute. Her work bridges clinical surgery and translational vascular biology, with a focus on aortic diseases and diabetic vascular complications. Education: Ph.D. in Biomedical Sciences — University of New South Wales, Sydney, NSW, Australia M.D. — Beijing Medical College, Beijing, China Research Interests: Dr. Shen's research is centered on understanding the molecular mechanisms underlying aortic aneurysms and dissections. Her laboratory investigates signaling pathways that regulate aortic destruction, healing, and remodeling. She has developed innovative mouse models to study these processes and applies advanced techniques to assess aortic structure and function. A key translational goal is the development of pharmacological strategies to prevent progressive aortic disease. She also explores diabetic vascular diseases and the role of inflammation and metabolic dysfunction in vascular biology. Recent Research Trends: Her recent publications (2017–2023) emphasize epigenetic regulation, single-cell transcriptomics, inflammasome signaling, and the role of innate immune pathways such as STING and NLRP3 in aortic degeneration. There is a consistent focus on identifying therapeutic targets for aortic aneurysm and dissection, including the adverse effects of drugs like ciprofloxacin in genetically predisposed individuals. Scientific Awards: Dr. Mark L. Entman Teaching Award for Excellence in Cardiovascular Education (2023) Grants & Funding: Dr. Shen has received major funding from the NHLBI, including an R01 grant awarded jointly with Dr. LeMaire, to study gender differences in aortic disease. Her lab is supported by multiple federal and institutional grants aimed at dissecting the molecular basis of vascular pathology and developing targeted therapies. Laboratory & Team: She directs the Aortic Disease Research Laboratory at Baylor College of Medicine, in collaboration with the Texas Heart Institute. Her team includes postdoctoral fellows, graduate students, and research staff working on translational vascular biology projects.

• Cardiovascular Physiology
• Sex Differences in Physiology
• Women's Cardiovascular Health
• +۷ مورد دیگر

Charlotte Usselman, PhD is an Associate Professor and Associate Investigator at the Research Institute of the McGill University Health Centre (RI-MUHC), where she leads research within the Cardiovascular Health Across the Lifespan Program. Her work bridges cardiovascular physiology and gender-specific medicine, with a particular focus on understanding how sex differences and gonadal hormones influence cardiovascular regulation and health outcomes across diverse populations. Dr. Usselman's research program centers on the neurovascular control of blood pressure and cardiovascular health, employing integrative physiology approaches to study mechanisms across various age groups and clinical conditions. Her laboratory investigates how perturbations to the gonadal hormone milieu—including conditions like polycystic ovary syndrome and postmenopause—affect cardiovascular regulation. Her work has established important connections between sex hormones, sympathetic nervous system activity, and vascular function, highlighting critical sex-specific differences in cardiovascular physiology that have implications for clinical practice and research design. Analysis of her recent publications reveals a strong emphasis on sex as a biological variable in cardiovascular research, with particular attention to women's health conditions. Her work spans multiple methodologies including direct neural recordings, vascular function assessments, and hormonal manipulations, consistently demonstrating how sex differences manifest in cardiovascular responses to stressors, exercise, and disease states. This body of work has contributed significantly to understanding why cardiovascular disease presents differently in women and men. Dr. Usselman has been instrumental in developing guidelines for incorporating sex and gender considerations into cardiovascular research, as evidenced by her 2024 invited review in the American Journal of Physiology - Heart and Circulatory Physiology . Her systematic reviews and meta-analyses on topics like physical fitness in women with polycystic ovary syndrome have helped synthesize complex findings across multiple studies. Her laboratory actively investigates the cardiovascular implications of polycystic ovary syndrome, examining how androgen excess and body composition affect endothelial function and blood pressure regulation. This work has important clinical implications for understanding the elevated cardiovascular risk in women with this condition. Additionally, her research on salivary versus blood hormone assessments has provided valuable methodological insights for researchers studying female participants.

Joo-Seop Parkمشاهده پروفایل

استاد

• Nephrology
• Kidney Development
• Molecular Biology
• +۳ مورد دیگر

Joo-Seop Park is a Professor in the Department of Medicine, specializing in Nephrology and Hypertension, at the Feinberg School of Medicine, Northwestern University. He maintains a primary research affiliation with the Feinberg Cardiovascular and Renal Research Institute, where his laboratory investigates molecular mechanisms underlying kidney development and disease pathogenesis. Dr. Park's research centers on transcriptional regulation during renal organogenesis, with particular emphasis on the roles of Tcf21, Hnf4a, and β-catenin in nephron formation, stromal cell differentiation, and podocyte development. His work integrates single-cell transcriptomics, genome-wide cistromic analyses, and sophisticated mouse genetic models to dissect cell fate determination processes in renal progenitors. Key investigations include the molecular basis of proximal tubule development, mechanisms of renal fibrosis, and transcriptional networks governing urinary bladder morphogenesis. His publications consistently bridge fundamental developmental biology with clinical implications for kidney disorders. Analysis of Dr. Park's recent publications (2018-2025) reveals a cohesive research trajectory focused on transcriptional control in renal development. His work demonstrates how specific transcription factors orchestrate nephron segmentation, stromal cell differentiation, and epithelial maturation. Notable contributions include elucidating Tcf21's role in renal stromal fate determination, Hnf4a's critical function in proximal tubule development, and Wnt/β-catenin signaling in nephron formation. His research increasingly incorporates single-cell technologies to resolve cellular heterogeneity in kidney fibrosis and developmental processes. Scientific Awards: No scientific awards or honors mentioned in the provided text Advising and Grants: No information regarding students, mentees, or research grants was provided in the source material Dr. Park conducts his research within the Feinberg Cardiovascular and Renal Research Institute, leveraging institutional resources for advanced genomic and imaging technologies. His laboratory maintains active collaborations with nephrology clinicians and developmental biologists to translate basic findings into potential therapeutic approaches for kidney diseases.

Raymond Reynoldsمشاهده پروفایل

دانشیار

• Vestibular System
• Sensory-Motor Control
• Postural Sway
• +۵ مورد دیگر

Dr. Raymond Reynolds is an Associate Professor in the School of Sport, Exercise and Rehabilitation Sciences at the University of Birmingham . His research focuses on the Vestibular System , Sensory-Motor Control , and Postural Sway , with significant work on Ankle Stiffness and Physiological Tremor . 2025: Leading a feasibility study on Electrical Vestibular Stimulation in Children (Birmingham Women's Charitable Funds). 2023-2027: Principal Investigator for A novel diagnostic for vestibular dysfunction (Medical Research Council). 2022-2025: Co-Investigator in Mild Traumatic Brain Injury Biomarker Study (Ministry of Defence). His recent publications (2024-2025) explore haptic feedback in balance, bed rest effects on vestibular control, and ankle-calf muscle dynamics . He serves on the Editorial Board of Experimental Physiology since 2017.

Michael D Ellisمشاهده پروفایل

استاد

• Stroke Rehabilitation
• Motor Control
• Neurorehabilitation
• +۳ مورد دیگر

Michael D Ellis is a Professor in the Department of Physical Therapy and Human Movement Sciences at the Feinberg School of Medicine, Northwestern University, where he conducts pioneering research at the intersection of neuroscience, biomechanics, and rehabilitation engineering to advance stroke recovery interventions. His research program focuses on quantifying motor impairments in chronic stroke survivors, particularly flexion synergy and loss of independent joint control in the upper extremity. He employs robotic systems (including the ACT3D platform), shear wave ultrasound elastography , and EMG-based pattern recognition to develop objective assessment tools and targeted therapies. A hallmark of his work is the investigation of progressive abduction loading as a mechanism to overcome gravity-induced discoordination, with significant contributions to understanding the biomechanical basis of elbow contracture and spasticity. Analysis of his 2019-2024 publications reveals three dominant research trajectories: (1) Development of mechatronic evaluation systems for inpatient stroke assessment with established test-retest reliability; (2) Cross-validation of biomechanical measures (e.g., ultrasound elastography as proxy for passive torque); (3) Neuroengineering applications using machine learning to decode movement intent for robotic rehabilitation. His work consistently bridges laboratory findings to clinical practice through quantitative metrics that differentiate impairment subtypes.

Christopher Richardsمشاهده پروفایل

استاد

• Neuroscience
• Receptor Biology
• Nicotinic Acetylcholine Receptors
• +۸ مورد دیگر

Christopher Richards is a Professor in the Department of Chemistry at University of Kentucky, with significant affiliations including the Markey Cancer Center/Cancer Research Priority Initiative, Neuroscience Research Priority Area, Substance Use Priority Research Area, and Translational Oncology Research Program. His research spans multiple disciplines with a focus on receptor neuroscience, particularly nicotinic acetylcholine receptors, and the application of single-molecule imaging techniques to understand cellular processes. Dr. Richards earned his Doctor of Philosophy from Georgia Institute of Technology in 2009. His research profile shows significant expertise in: Receptor Neuroscience (100%) Nicotinic Acetylcholine Receptor Neuroscience (70%) Nicotinic Receptor Neuroscience (67%) Cell Membrane Neuroscience (64%) Endoplasmic Reticulum Neuroscience (63%) Stoichiometry Biochemistry, Genetics and Molecular Biology (48%) Macrophage Medicine and Dentistry (46%) Single Molecule Imaging Biochemistry, Genetics and Molecular Biology (37%) His research program is highly active with 66 publications and 54 projects and grants, including significant funding from the National Institute on Aging, National Institute of Allergy and Infectious Diseases, and Craig H. Neilsen Foundation. Recent work focuses on macrophage-engineered vesicles for cancer treatment, blood-brain barrier research related to nicotine withdrawal, and single-molecule analysis of receptor assembly in neural and cardiac tissues. His publications since 2023 reveal strong trends toward vesicle-based cancer therapeutics, particularly for ovarian cancer, and sophisticated single-molecule techniques to study receptor assembly and function. The research demonstrates significant interdisciplinary collaboration across neuroscience, cancer biology, and infectious disease fields. Dr. Richards has received research recognition including a notable award in 2023. His work contributes to UN Sustainable Development Goals, particularly in areas related to health and well-being. His research group maintains active collaborations across multiple departments, with current projects including "Blood-Brain Barrier Dysfunction in Alzheimer's Disease," "Understanding the Mechanism of SARS-CoV-2 Entry by Single-Molecule Approaches," and "Engineered Nanovesicles For Macrophage Reprogramming In Spinal Cord Injury." These projects demonstrate both fundamental scientific inquiry and translational applications.

G. Vazquezمشاهده پروفایل

استاد

• Atherosclerosis
• Cardiovascular Disease
• Ion Channels
• +۷ مورد دیگر

G. Vazquez is a tenured Professor in the Department of Physiology and Pharmacology at the University of Toledo College of Medicine, where he has held leadership roles such as Program Director of the Medical Sciences Program (MSBS-MS) and Associate Director of the Center for Hypertension and Precision Medicine since 2015. His research focuses on the molecular mechanisms of atherosclerosis and cardiovascular disease, particularly the roles of TRPC channels and nicotinic acetylcholine receptors in endothelial dysfunction, macrophage survival, and inflammation. Education: BSc and PhD in Biochemistry from National University of the South, Argentina Postdoctoral Training: CONICET (Argentina), NIEHS (USA) His lab employs in vitro and in vivo models, including transgenic and knockout mice, to investigate calcium signaling pathways in vascular pathologies. Recent studies highlight TRPC3's role in endoplasmic reticulum stress, macrophage efferocytosis, and atherosclerotic plaque stability. Notable awards include the 2017 Dean's Award for Mentoring and 2011 Dean’s Award for Research to New Investigator at the University of Toledo. He serves as an honorary mentor for the Graduate Program on Biochemistry and Pharmacology at his alma mater and actively participates in professional societies like the American Heart Association and American Society for Pharmacology & Experimental Therapeutics.

Eili Tranheim Kaseمشاهده پروفایل

دانشیار

• Pharmacology
• Physiology
• Type 2 Diabetes
• +۵ مورد دیگر

Eili Tranheim Kase is a Professor and current Associate Professor at the University of Oslo , affiliated with the Department of Pharmacology and Pharmaceutical Biosciences . Her research focuses on energy metabolism in human skeletal muscle cells, particularly its role in the pathophysiology of Type 2 diabetes and obesity . She actively teaches pharmacology, physiology, and pharmacotherapy at both bachelor's and master's levels. Education: Cand.pharm. (2002), University of Oslo PhD (2007), University of Oslo Her research explores mechanisms like the LXR pathway , SENP2 regulation , and AMPK function in metabolic disorders, with recent work on myotube models for drug testing and 3D culture systems . Key article trends include lipid-glucose interactions , exercise mimetics , and nutraceutical effects on muscle metabolism. Scientific Awards: Fulbright Research Scholar (2022/2023) She supervises master's and PhD students and collaborates with Professor Christopher Glass at UCSD. Her work is part of the MetHealth research group, which investigates metabolic regulation in health and disease.

• Biomedicine
• Neurosciences
• Mitochondrial Diseases
• +۳ مورد دیگر

Professor Henna Tyynismaa serves as Vice Dean of Research at the Faculty of Medicine, University of Helsinki , affiliated with the Department of Medical and Clinical Genetics (Medicum). Her research focuses on Biomedicine and Neurosciences , particularly Mitochondrial Diseases and Motor Neuron Disorders . Key research areas include: Mitochondrial dysfunction in neurodegeneration Genetic mechanisms of Charcot-Marie-Tooth disease Metabolic biomarkers for neuromuscular disorders Stem cell modeling of inherited neuropathies Notable scientific awards: Best PhD thesis , Faculty of Medicine, Helsinki (2007) University of Helsinki Biomedical Thesis Award (2007) Current projects: Sigrid Juselius Foundation (2023-2026): Investigating CHCHD10 dysregulation in motor neuron disease MetaStem Centre of Excellence (2023-2025): Exploring Stem Cell Metabolism in disease contexts She actively supervises doctoral students in multiple programs and contributes to peer review for journals like European Journal of Human Genetics and Frontiers in Genetics .

• Zootechnics
• Animal Nutrition
• Pig Breeding
• +۴ مورد دیگر

Professor Wojciech Kozera works at the University of Warmia and Mazury in Olsztyn in the Department of Animal Bioengineering. His research focuses on zootechnics with particular emphasis on pig breeding, hepatoprotective effects of silymarin, transcriptome analysis, and mycotoxin research in pig feed. He is currently supervising doctoral students with available research funds and infrastructure. Scientific Discipline: Zootechnics and Fishing Supervision: 2 promoted doctors, currently no active doctoral students Research interests include: Animal Nutrition (guar meal supplementation, soybean alternatives), Feed Safety (mycotoxins, Fusarium fungi), Meat Quality (fatty acid profiles, physicochemical properties), and Animal Health (liver morphology, nitrogen balance). Scientific achievements: 12/16 WoS/Scopus publications , 149 Google Scholar citations , H-index 7 . Current projects involve hepatoprotective effects of silymarin using pig models for liver dysfunction research. Laboratory/Department Infrastructure: Confirmed availability of resources for supervising doctoral students Research Funding: Confirmed financial support for projects

• Cellular stress responses
• Functional genomics
• Cell signaling
• +۵ مورد دیگر

Peter Thorlund Haahr is an Associate Professor in the Department of Cellular and Molecular Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences. His research program focuses on Transcription, RNA, and Gene Medicine, investigating fundamental cellular processes with implications for human disease. Dr. Haahr's primary research focuses on the molecular mechanisms of cellular stress responses and functional genomics. His laboratory aims to identify and characterize new genes that play important roles in human disease by studying basic mechanisms of cellular stress responses and gene expression. The lab employs a combination of unbiased proteome- and genome-wide screens as well as targeted molecular and cell biological approaches to understand how cellular stress responses function as dynamic signaling networks controlling adaptation mechanisms against environmental challenges. His recent publications demonstrate a strong focus on cellular stress response mechanisms, particularly how these responses interact with transcriptional and translational machinery. His work spans diverse areas including DNA damage response, protein synthesis regulation during stress, and the role of specific enzymes in cellular fitness. The research has significant implications for understanding and treating cancer and age-related neurodegenerative disorders. Dr. Haahr's laboratory combines targeted cell biology, biochemistry, and synthetic biology approaches with cutting-edge systems-wide screening strategies to elucidate cellular processes in human cells. Current research specifically investigates mechanisms of translation regulation during stress, SUMO-targeted ubiquitination in proteostatic stress responses, and genetic compensation by adaptive gene expression.