جست‌وجوی استاد و پژوهشگر

• Nuclear envelope biology
• Endoplasmic reticulum biology
• Protein quality control
• +۱۰ مورد دیگر

Christian Schlieker is a Professor of Molecular Biophysics and Biochemistry and Professor of Cell Biology at Yale University School of Medicine. He serves as Director of Undergraduate Studies in the Department of Molecular Biophysics and Biochemistry and is a member of the Advisory Board of the Yale Center for Molecular Discovery. His research spans multiple interdisciplinary programs including the DNA Damage and Genome Integrity Program, Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS), and the Yale Cancer Center. Dr. Schlieker's research focuses on the cellular etiology of movement disorders, with particular emphasis on nuclear compartmentalization and biomolecular condensates. His lab explores how cells build and safeguard the nuclear envelope and endoplasmic reticulum to ensure protein quality control and cellular homeostasis. They investigate how disruptions in membrane organization and phase separation drive the formation of aberrant condensates connected to neurological diseases, particularly movement disorders like dystonia. The lab develops and applies new tools to probe and modulate these processes across scales, integrating cell biology, biochemistry, and computational approaches to uncover fundamental principles of cellular organization. Analysis of Dr. Schlieker's recent publications (2020-2025) reveals a strong focus on nuclear envelope biology, protein quality control mechanisms, and the role of biomolecular condensates in neurological disorders. His work bridges fundamental cell biology with disease mechanisms, particularly in understanding how Torsin ATPases maintain nuclear envelope integrity and how their dysfunction leads to movement disorders. The research spans from molecular mechanisms to potential therapeutic strategies, with several papers identifying small molecule modulators of pathological condensates. Scientific Recognition: NIH Director's New Innovator Award (2011) Service on scientific advisory board of Dystonia Medical Research Foundation Reviewer for NIH, Department of Defense, German Excellence Initiative, and European Research Council As Director of Undergraduate Studies, Dr. Schlieker plays a significant role in academic administration at Yale College. His lab actively recruits graduate students, postdocs, and undergraduates, emphasizing interdisciplinary training that combines biochemical, cellular, and computational approaches. The Schlieker Lab collaborates extensively through the Yale Nucleus Club with the Bahmanyar, King, and Lusk laboratories, creating a rich environment for scientific exchange and skill development. Current research directions include identifying small molecules that modulate aberrant condensates, investigating condensates in neurodevelopmental disorders using patient iPSC lines, establishing FRET-based readouts for protein folding, and elucidating the molecular function of torsin proteins in nuclear pore complex assembly.

Jaime Gnauمشاهده پروفایل

استادیار بالینی

• Nutrition and Dietetics
• Food Insecurity Intervention
• Intuitive Eating
• +۵ مورد دیگر

Jaime Gnau is a Clinical Assistant Professor in the Nutrition and Dietetics program within the School of Health Sciences at Missouri State University. She serves as a registered dietitian nutritionist at the MSU Care Clinic on campus, providing nutritional care to patients while integrating clinical practice with academic instruction. With over 20 years of healthcare experience, Dr. Gnau brings extensive practical knowledge to her teaching and research activities, focusing on evidence-based nutrition strategies to promote accessible nutrition for health improvement and well-being. Education MS, Health Promotion and Wellness Management, 2020, Missouri State University BS, Dietetics, 2017, Missouri State University CHES certification, 2020 RYT 200 certification, 2023 Research Interests Dr. Gnau's research focuses on practical nutrition applications that address community health needs. Her primary areas include food insecurity intervention strategies, intuitive eating approaches, and interprofessional education to enhance student learning in clinical settings. She emphasizes evidence-based practice and translating research into practical community applications, particularly for underserved populations. Her recent publications show a strong focus on consumer nutrition education, with articles covering food label interpretation, dietary patterns like the Nordic Diet, GMO information, and healthy food choices. These works demonstrate her commitment to translating complex nutrition science into accessible information for the general public. Professional Recognition Emerging Dietetic Leader Award (MOAND) MCHHS Dean's Award for Academic Partnership Excellence in Connecting Health to the Community Award (MOCAN) Leadership roles in Missouri Academy of Nutrition and Dietetics Academic Guidance Dr. Gnau teaches multiple undergraduate and graduate courses in the Nutrition and Dietetics program, including Social and Behavioral Applications in Human Nutrition, Food Science, Food and Culture, and specialized topics courses. Her teaching philosophy emphasizes evidence-based practice, reducing nutrition-related stress, and building positive relationships with food. She supervises student practicums in population health, food service management, and medical nutrition therapy. Community Engagement Through her work at the MSU Care Clinic, Dr. Gnau provides nutrition services to underserved populations while offering valuable clinical training opportunities for students. She actively contributes to professional organizations and has developed media content to educate the public about nutrition topics through major publications including Authority Magazine, Forbes Health, and INSIDER.

David Greeningمشاهده پروفایل

استاد

• Extracellular Vesicles
• Cardiovascular Research
• Proteomics
• +۶ مورد دیگر

Professor David Greening is Head of Molecular Proteomics at Baker Heart and Diabetes Institute and leads the Baker Department of Cardiovascular Research, Translation and Implementation at La Trobe University. He holds affiliate positions at Monash University and University of Melbourne, and serves as Director of the Proteomics and Metabolomics Platform at La Trobe University. His educational background includes a BSc(Hons) and PhD from the University of Melbourne, followed by postdoctoral training at Ludwig Institute for Cancer Research, La Trobe University, and Institute for Systems Biology in Seattle. He completed Biomedical Research Management certification at the University of Melbourne in 2014. Professor Greening's research focuses on extracellular vesicle (EV) biology and their therapeutic applications in cardiovascular disease. His laboratory employs advanced proteomics, mass spectrometry, and nanobiotechnology to understand EV mechanisms and develop next-generation cell-free therapies. Key research areas include engineering EVs for cardiovascular therapeutics, developing EV-based diagnostics, understanding cardiac remodeling using human cardiac organoids, and repairing cardiac tissue through exosome-mediated regeneration. His publication record includes 148 papers with over 24,500 career citations and an h-index of 52, with work published in top journals including Nature Methods, Circulation Research, and Journal of Extracellular Vesicles. His research demonstrates strong trends toward therapeutic applications of EVs, particularly for cardiac repair, and the development of proteomic technologies to understand complex biological systems. Helen Amelia Hains Fellow and Baker Fellow Australian Field Leader (outright) – Proteins, Proteomics Chair, International Society of Extracellular Vesicles Congress (2024) Highly Cited Researchers 2020 (top 1%) by Stanford University International Protein Society Hans Neurath Outstanding Promise Award ROYAN International Research Award on Stem Cell Biomedicine Professor Greening has established significant industry collaborations with Tithon Biotech, Takeda Pharma, and Thermo Fisher Scientific. He has successfully mentored numerous students and researchers, with his lab comprising molecular biologists, cell biologists, proteomics specialists, and clinical scientists working collaboratively. His research has advanced to pre-clinical and clinical utility with several commercialization outcomes. The Molecular Proteomics laboratory operates as a multidisciplinary team focused on understanding EV function and developing innovative proteomic technologies. They collaborate extensively with national and international partners in biotechnology, proteomics, and regenerative medicine fields, maintaining strong industry networks that facilitate translation of basic research findings into clinical applications.

Kevin Huynhمشاهده پروفایل

پژوهشگر ارشد

• Lipidomics
• Mass spectrometry
• Lipid Metabolism
• +۴ مورد دیگر

Dr. Kevin Huynh is a Research Fellow and Group Leader at the Baker Heart and Diabetes Institute, holding an NHMRC Emerging Leadership Fellowship. He maintains academic appointments at both La Trobe University within the Baker Department of Cardiovascular Research, Translation and Implementation and at the University of Melbourne within the Baker Department of Cardiometabolic Health. Dr. Huynh's educational background includes: Bachelor of Science in Human Pathology from the University of Melbourne Honours year completed in 2011 at the University of Melbourne examining secretases in Alzheimer's disease PhD completed in 2019 from Monash University under Professor Peter Meikle and Associate Professor Brian Drew Dr. Huynh's research focuses on developing mass spectrometry techniques for lipid analysis, with particular emphasis on understanding lipid metabolism in neurodegenerative and metabolic diseases. His laboratory has established a comprehensive lipidomics platform that enables high-throughput profiling of lipid metabolites in human plasma. This platform has been instrumental in characterizing lipid signatures associated with Alzheimer's disease, type 2 diabetes, and cardiovascular conditions. His recent publications demonstrate a strong trend toward understanding the relationship between lipid metabolism and disease mechanisms through large cohort studies and multi-omics integration. His work increasingly incorporates machine learning approaches to analyze complex lipidomic datasets and identify biomarkers for early disease detection and risk stratification. Dr. Huynh's scientific achievements include: NHMRC EL1 Investigator grant (2021–2025) for research on lipid metabolism in Alzheimer's disease ARC Discovery Project grant as Chief Investigator A (2023–2025) for novel lipidomic analysis methods Sir Laurence Muir Prize from Baker Institute (2021) John Funder Award for Best Early Career Scientist presentation (2021) Multiple invitations to present at international conferences including the Metabolomics Society and ASMS As a Group Leader, Dr. Huynh oversees a research program that has secured significant funding and established collaborations across multiple institutions. His NHMRC fellowship supports his investigation into lipid metabolism in Alzheimer's disease using peripheral immune cells, while his ARC Discovery Project focuses on developing high-throughput lipidomic analysis approaches. Dr. Huynh leads the Metabolomics Laboratory at the Baker Heart and Diabetes Institute, where his team specializes in mass spectrometry-based lipid analysis. The laboratory has developed advanced methodologies for high-throughput lipid profiling and has contributed significantly to understanding the lipid signatures associated with various diseases, with strong connections to clinical researchers for translational applications.

W.W.M. (Pim) Pijnappelمشاهده پروفایل

دانشیار

• Stem Cell Biology
• Lysosomal Storage Diseases
• Genome Engineering
• +۳ مورد دیگر

W.W.M. (Pim) Pijnappel serves as Associate Professor in the Department of Pediatric Metabolic Diseases at Erasmus University Rotterdam and Head of Basal Research at the Center for Lysosomal and Metabolic Diseases, Erasmus MC Rotterdam, a position held since 2012. His academic credentials include: MSc in Medical Biology from Utrecht University, Netherlands PhD from Utrecht University, Netherlands (1996) Pijnappel's research integrates stem cell biology, genome engineering, and epigenetic mechanisms to address lysosomal storage disorders. His work specifically targets skeletal muscle, cartilage, and central nervous system pathologies in Pompe disease and Mucopolysaccharidoses (MPS), developing disease models and novel therapeutic approaches through genetic engineering. Publication analysis reveals a strategic research evolution from foundational molecular discoveries (epigenetic regulation, 2001; genome editing techniques, 2003) toward translational stem cell applications for rare diseases (2013). This trajectory demonstrates consistent high-impact contributions across molecular biology, regenerative medicine, and rare disease therapeutics. He directs the Molecular Stem Cell Biology of Lysosomal Storage Diseases research group, focusing on metabolic enzyme deficiencies that cause systemic accumulation of substrates and multi-organ damage, with emphasis on stem cell-based therapeutic development.

Juan Socorro Armendariz Borundaمشاهده پروفایل

پژوهشگر

• Liver Diseases
• Epigenetics
• NASH/MAFLD
• +۶ مورد دیگر

Dr. Juan Socorro Armendariz-Borunda serves as an Adjunct Researcher at Tecnológico de Monterrey's School of Medicine and Health Sciences, where he leads research in the Biomarkers and Advanced Therapies group. With a distinguished career spanning over 30 years of teaching at Universidad de Guadalajara, he holds a PhD in Biochemistry from Centro de Investigación y de Estudios Avanzados del IPN. His research program focuses on liver diseases, particularly NASH/MAFLD, epigenetic mechanisms, and the gut-liver axis, with significant contributions to nanomedicine and ophthalmology applications. His research interests center on the therapeutic applications of pirfenidone in liver fibrosis and NASH, epigenetic regulation in hepatocarcinoma, and the development of nutraceutical interventions using Mexican ancestral foods. His work bridges basic science with clinical applications, particularly in developing novel therapeutic strategies for metabolic-associated liver diseases and exploring the molecular mechanisms underlying obesity-related complications. Analysis of his recent publications reveals a strong focus on translational research, with particular emphasis on epigenetic mechanisms in liver disease, nanotechnology applications in hepatocellular carcinoma treatment, and the therapeutic potential of traditional Mexican foods for metabolic disorders. His work demonstrates significant interdisciplinary integration between hepatology, epigenetics, and nutritional science. Premio Nacional de Ciencias, José Mario Molina Pasquel y Henríquez (2023) 30 years of teaching recognition from Universidad de Guadalajara (2024) Multiple first and second place awards in national medical research competitions Honorable mentions in hepatology and metabolic disease research Recognition for contributions to molecular biology in medicine Dr. Armendariz-Borunda has supervised numerous research projects and mentored students through programs like the National Social Service in Health Research. His collaborative work extends across multiple institutions in Mexico, with significant contributions to clinical trials on pirfenidone and studies on traditional Mexican foods for metabolic health. He maintains active research laboratories focused on liver disease mechanisms and therapeutic interventions. His current work emphasizes the development of biomarker-based diagnostic approaches and advanced therapeutic strategies for metabolic-associated liver diseases.