جست‌وجوی استاد و پژوهشگر

Arne Traulsenمشاهده پروفایل

استاد

• Evolutionary Dynamics
• Evolutionary Game Theory
• Finite Populations
• +۴ مورد دیگر

Prof. Dr. Arne Traulsen is a Scientific Member and Director of the Department of Theoretical Biology at the Max Planck Institute for Evolutionary Biology in Plön, Germany. He leads interdisciplinary research integrating biology, physics, mathematics, and computer science to study evolutionary dynamics, particularly in cancer evolution, metaorganisms, and population structure. His work often involves collaborations with clinicians, experimentalists, and bioinformaticians. Education: Diploma in Theoretical Physics (2002) Doctorate from Kiel University (summa cum laude, 2005) Research Interests: Arne’s research focuses on evolutionary game theory, finite populations, group selection, mathematical models for cancer , and population structure . His team explores how mutations accumulate, how cooperation evolves, and how eco-evolutionary dynamics shape biological systems. Recent work connects chaotic turnover in ecosystems and evolutionary responses to treatment with broader biological questions. Scientific Awards: Postgraduate Grant of Studienstiftung des Deutschen Volkes Postdoc Grant of Deutsche Akademie der Naturforscher Leopoldina Emmy-Noether Grant of Deutsche Forschungsgemeinschaft Young-Scientist Award for Socio- and Econophysics (2012) Advising and Collaborations: While specific student names are not listed, Arne has hosted numerous research groups and mentored interdisciplinary teams. His work spans collaborations with institutions like Kiel University , the CRC 1182 Metaorganisms , and global researchers in evolutionary biology and computational modeling .

Christian Kostمشاهده پروفایل

استاد

• Evolution of Cooperation
• Microbial Ecology
• Bacterial Metabolic Networks
• +۴ مورد دیگر

Prof. Dr. Christian Kost is a Professor in the Department of Ecology at the University of Osnabrück. His research focuses on the molecular and ecological mechanisms underlying cooperative interactions between organisms, particularly metabolic cross-feeding in bacteria. He leads the Experimental Ecology and Evolution group, investigating how cooperation evolves and its physiological consequences. Key research topics include the evolution of cooperation, synergistic coevolution, microbial community dynamics, bacterial multicellularity, and phenotypic heterogeneity. Methodologies employed include experimental evolution, synthetic ecology, genomics, microscopy/microfluidics, and theoretical modeling. Recent work highlights obligate cross-feeding’s role in expanding bacterial metabolic niches and the prevalence of reciprocity in mutualistic interactions. Kost’s lab has published influential studies on microbial symbiosis, including landmark papers in Nature Ecology & Evolution and Current Biology . Current projects explore ecological interaction networks, predator-prey dynamics (e.g., ciliate-bacteria), and synthetic microbial communities. The lab actively collaborates with international researchers and employs cutting-edge techniques like omics profiling and individual-based modeling (e.g., McComedy tool development). Recent lab additions include bachelor students Karmen Lohstroh, Pía-Kathleen Habekost, and Finn Dinnus. Kost’s work bridges theoretical and experimental approaches, aiming to define principles governing microbial cooperation and its ecological significance.

Seraphine V. Wegnerمشاهده پروفایل

استاد

• Synthetic Biology
• Cell Biology
• Photochemistry
• +۵ مورد دیگر

Seraphine V. Wegner is a Full Professor at the Institute of Physiological Chemistry and Pathobiochemistry within the Medical Faculty of the University of Münster. She leads an active research group focused on the spatiotemporal control of cell-material and cell-cell interactions using visible light. Her work bridges synthetic biology, cell biology, and photochemistry to create innovative approaches for tissue engineering and minimal cellular systems. Dr. Wegner's educational background includes a PhD from the University of Chicago (2005-2010) and undergraduate studies at Middle East Technical University in Turkey (2002-2005). Her career path has taken her through prestigious institutions including the Max Planck Institutes in Mainz and Heidelberg, where she established her independent research before joining the University of Münster as a Full Professor in 2019. Her research spans several interconnected areas including light-controlled minimal cellular systems, photoswitchable cell-cell interactions for tissue engineering, light-controlled cell-material interactions, and engineering designer biofilms with light. These research themes share a common thread of using light as a non-invasive tool to precisely control biological processes with high spatial and temporal resolution. Dr. Wegner's publication record shows consistent high-impact output across leading journals in cell biology, synthetic biology, and materials science. Her recent work demonstrates increasing sophistication in multi-color light control systems and applications in both fundamental biological questions and potential therapeutic approaches. ERC Consolidator Grant (2024): LIGHTHOUSE - Light as a signal for nonchemical cell-to-cell communication ERC Starting Grant (2018): ARTIST - Artificial cell-cell interactions for light switchable cell organization and signaling Young Leaders in Science Program, Schering Foundation (2016) MaxSynBio Independent Group Leader, BMBF/MPG (2015) Her research group actively collaborates across disciplines, with projects spanning from fundamental biophysics of cell adhesion to potential medical applications in tissue engineering and bacterial therapeutics. Dr. Wegner has established herself as a leader in the emerging field of optogenetic control of multicellular systems.

• Microbial Population Biology
• Evolutionary Genetics
• Ecological Scaffolding
• +۳ مورد دیگر

Paul Rainey is a Professor and Director of the Department of Microbial Population Biology at the Max Planck Institute for Evolutionary Biology in Plön, Germany. He also serves as Professor at ESPCI Paris and holds an adjunct position at the New Zealand Institute for Advanced Study (NZIAS). His research spans microbial evolution, ecological scaffolding, and biophysics, supported by the Max Planck Society and collaborations across institutions. University of Canterbury – BSc, MSc, PhD Paul's research focuses on experimental evolution, ecological complexity, and the emergence of individuality in microbial systems. Recent work explores evolutionary rescue, biophysical mechanisms of surface colonization, and the interplay between ecological and genetic factors in adaptation. His publications highlight interdisciplinary approaches, merging microbial ecology with theoretical frameworks for evolutionary transitions. Key themes include stochastic phenotype switching, genome streamlining, and the role of environmental structure in shaping evolutionary trajectories. Fellow of the Royal Society of New Zealand Member of EMBO Paul leads the Laboratory for Evolutionary Genetics at ESPCI Paris and collaborates with institutions like Kiel University and the CRC 1182. His work addresses microbial community dynamics, evolutionary medicine, and the broader implications of eco-evolutionary feedback in biological systems.

Susann Müllerمشاهده پروفایل

دانشیار

• Microbial Ecology
• Flow Cytometry
• Environmental Biotechnology
• +۵ مورد دیگر

Prof. Dr. Susann Müller is Senior Scientist and Group Leader of the Flow Cytometry Working Group at the Department of Applied Microbial Ecology, Helmholtz Center for Environmental Research (UFZ) in Leipzig, Germany. Since 2011, she has held an Associate Professor position for Microbiology at Leipzig University’s Faculty of Life Sciences, bridging fundamental microbial ecology with environmental biotechnology applications through single-cell analytics. Education: 1985: Diploma in Biochemistry, Martin Luther University Halle-Wittenberg 1992: PhD, University of Halle-Wittenberg (Population dynamics of S. cerevisiae) 2003: Habilitation, Technical University Dresden (Multiparametric Cytometry) Her research pioneers microbial community flow cytometry to extract single-cell high-dimensional data, applying macroecological concepts to quantify stability metrics (resistance, resilience, displacement speed, elasticity) in engineered systems. Current focus includes bio-based circular economy initiatives: developing the carboxylate platform for sustainable chemical production and biological phosphate recovery from wastewater streams for resource valorization. Recent publications (2021-2025) reveal consistent innovation in flow cytometry applications, with emphasis on stability assessment in bioreactors, predator-prey dynamics in complex communities, and real-time monitoring of wastewater systems. She integrates ecological theory with multi-omics and data science to decode microbial assembly principles across environmental, agricultural, and industrial contexts. Professional roles: President, German Society of Cytometry (DGfZ, 2008-2010) Associate Editor, Microbiology for Cytometry Part A ISAC Educational Committee (2011-2012) and Scholars Program Committee (2013-2015) Current grants: PHOM project (SMWK InfraProNet 2024-2027): €449,160 for wastewater phosphorus recovery Z-PROJECT (DFG 2022-2025): €556,550 for bacterial biofilm analysis PROMICON (EU H2020 2021-2025): €200,000 for industrial microbiome consortia Moore Foundation (2020-2024): $23,000 for archaeal evolutionary tools Chinese Scholarship Council (2022-2026): Artificial community construction The Flow Cytometry Working Group under her leadership at UFZ develops standardized mock communities (Nature Protocols 2020), automated analysis tools (flowEMMi), and cytometric barcoding methods. It collaborates with Leipzig University, Technical University Dresden, and international partners including UC Santa Barbara, driving innovations in real-time environmental monitoring and wastewater treatment optimization.

Silvia De Monteمشاهده پروفایل

پژوهشگر

• Ecology
• Evolutionary Biology
• Microbial Systems
• +۳ مورد دیگر

Silvia De Monte is a Researcher at the Max Planck Institute for Evolutionary Biology in Plön, Germany, and holds affiliations with the Institute of Biology at École Normale Supérieure in Paris, France. She leads the 'Dynamics of Microbial Collectives' group, focusing on the ecological and evolutionary processes underlying collective behaviors in microbial systems. Her work integrates mathematical modeling with empirical observations to explore how selection pressures shape collective functions in heterogeneous cellular assemblies. De Monte's research spans multiple areas, including the eco-evolutionary dynamics of aggregative multicellularity, the role of phenotypic heterogeneity in bacterial populations, and the mathematical modeling of species abundance distributions in planktonic communities. She has collaborated with institutions such as the CNRS, ENS Paris, and the University of Vienna, contributing to interdisciplinary projects at the interface of biology, physics, and economics. Her educational background includes a PhD from the Technical University of Denmark (2004) and postdoctoral training at the University of Vienna and the Max Planck Institute. She has held roles as a Researcher at CNRS (since 2007) and an Attached Lecturer at École Normale Supérieure (2014–2018). Key research projects include investigating the emergence of Darwinian properties in collective systems, the evolutionary stability of microbial symbioses, and the application of game theory to microbial social dynamics. Her work emphasizes the interplay between microscale cellular interactions and macroscale ecological patterns.

• Antibiotic Resistance
• Microbial Biotechnology
• Bacterial Physiology
• +۳ مورد دیگر

Prof. Dr. Susanne Gebhard is a Full Professor of Molecular Biotechnology at the Institute for Molecular Physiology , Johannes Gutenberg University (JGU) Mainz, Germany, since 2023. Her career spans international institutions, including postdoctoral work in New Zealand and the UK, and a permanent research and teaching position at the University of Bath. She focuses on bacterial physiology, particularly antibiotic resistance mechanisms and microbially induced calcite precipitation for sustainable biotechnology applications. Education: Abitur (1996), University Degree (2003), PhD in Microbiology (2006, University of Otago, New Zealand), Habilitation (2014) Research Interests: Her work bridges two major themes: Antibiotic Resistance : Investigating how bacteria detect antibiotics and regulate resistance pathways, with implications for novel therapeutic strategies. Microbial Biomineralization : Exploring bacterial mineralization processes to reduce cement usage in construction, addressing CO 2 emissions through Solibacillus silvestris and related species. Publications & Collaborations highlight her expertise in Bacillus subtilis , Pseudomonas , and Neisseria systems, alongside contributions to journals like Nature Communications , Cell Reports , and Environmental Microbiology . She frequently collaborates with labs in Oxford, Cologne, and Australia. Scientific Engagement includes: Senior Editor for the Microbiology journal Deputy Spokesperson for the 'Regulation' specialist group of the Association for General and Applied Microbiology Active participation in international conferences and EMBO workshops Lab & Leadership : She leads the Gebhard Lab at JGU Mainz, mentoring students and postdocs while emphasizing interdisciplinary collaboration. Her hobbies include horseback riding, gardening, and exploring the intersection of science and sustainability.

Philip Bittihnمشاهده پروفایل

پژوهشگر ارشد

• Nonlinear Dynamics
• Biological Physics
• Active Matter
• +۶ مورد دیگر

Dr. Philip Bittihn serves as Group Leader and Scientist at the Max Planck Institute for Dynamics and Self-Organization in Göttingen, Germany, heading the Emergent Dynamics in Living Systems research group within the Department of Living Matter Physics. His work bridges physics and biology to decipher complex emergent behaviors in biological systems through innovative interdisciplinary approaches. His research spans nonlinear dynamics in biological systems , initially focusing on cardiac arrhythmia mechanisms where he identified novel termination strategies for life-threatening rhythms through topological defect analysis. Current work centers on growth-driven phenomena in cellular active matter , investigating mechanical interactions, expansion flows, orientational order, and shape development coupled with gene regulation and metabolism. He employs reaction-diffusion modeling, synthetic biology, and microfluidic experimentation to study pattern formation in microbial colonies and cardiac tissue. Analysis of recent publications reveals a dominant trend toward active matter physics in multicellular systems , particularly geometry-induced nematic order, phase separation in proliferating matter, and nutrient-mediated antibiotic responses. His group consistently explores how non-equilibrium growth processes generate complex patterns, with increasing emphasis on mechanical stress anisotropy and motility-induced transitions in confined cellular environments. The Emergent Dynamics in Living Systems group operates at the physics-biology interface, utilizing genetically engineered E. coli models (as demonstrated in their Nature Microbiology 2020 work on oscillating growth patterns), advanced microfluidic chambers, and computational frameworks to investigate fundamental principles of biological organization with potential biomedical applications.

• Mathematical Biology
• Computational Modeling
• Biophysics
• +۳ مورد دیگر

Sabine Fischer is a Professor for Supramolecular and Cellular Simulations at the University of Würzburg’s Center for Computational and Theoretical Biology (CCTB). She holds a PhD in Mathematics from the University of Nottingham (2009) and completed postdoctoral research at the University of Cambridge (2009-2011) and the University of Frankfurt (2011-2017). Her work focuses on mathematical modeling and data-driven simulations of biological processes across subcellular, multicellular, and multi-tissue scales. Key research areas include agent-based modeling of parasite collective behavior (e.g., Project 7 of SPP 2332 PoP), cell-cell interactions, and morphological modeling with Blender. Her group develops tools for image analysis and applies methods ranging from classical statistics to machine learning. Education: Diploma in Mathematics, University of Würzburg PhD in Mathematical Biology, University of Nottingham (2009) Professional Experience: Postdoc, University of Cambridge (2009-2011) Postdoc, University of Frankfurt (2011-2017) Development Engineer, h.a.l.m. Elektronik GmbH (2017-2018) Professor, University of Würzburg (since 2018) Her research integrates experimental data with computational models to study processes like mouse blastocyst differentiation, tissue-level organization, and parasitic locomotion. Current projects emphasize agent-based modeling of Trypanosoma collective behavior and the development of open-source tools like VESNA for 3D vessel analysis.

Britta Trappmannمشاهده پروفایل

پژوهشگر

• biomaterials
• synthetic hydrogels
• cell-matrix interactions
• +۴ مورد دیگر

Britta Trappmann is a researcher at the Max Planck Institute for Molecular Biomedicine and a member of the Cells in Motion Cluster of Excellence. She leads the Bioactive Materials Laboratory , focusing on biomaterials , synthetic hydrogels , and the interplay between cell-matrix interactions and cellular mechanotransduction to understand angiogenesis and tissue engineering . Trappmann’s research develops synthetic extracellular matrices with tunable properties (mechanics, degradability, adhesiveness) to study cell migration , endothelial cell behavior , and vascular morphogenesis . Her work bridges biomedical engineering , cell biology , and materials science , emphasizing interdisciplinary collaboration. Her 15 most recent publications span angiogenesis (e.g., Adv Sci 2024, Nat Commun 2021), cell mechanotransduction (e.g., Angew Chem Int Ed 2006), and biomaterials engineering (e.g., Nat Mater 2012). These studies often employ 3D organotypic cell culture models and synthetic hydrogels to dissect how material properties influence cell behavior , including endothelial cell migration , collective cell dynamics , and vascular junction stability . Trappmann is a board member of the CiM-IMPRS Graduate Programme , mentoring junior scientists. Her lab utilizes advanced tools like spinning-disc microscopes to observe 3D cell migration in real-time and creates engineered tissue platforms for angiogenesis studies. She emphasizes translating basic research into medical applications , envisioning implantable artificial tissues .

Seraphine Wegnerمشاهده پروفایل

استاد

• Cell Biology
• Molecular Biology
• Biochemistry
• +۶ مورد دیگر

Prof. Seraphine Wegner is a Full Professor at the Institute of Physiological Chemistry and Pathobiochemistry within the Faculty of Medicine at the University of Münster. Her research focuses on developing light-controlled systems for precise spatiotemporal manipulation of cellular processes, with applications in synthetic biology, tissue engineering, and cell-material interactions. Dr. Wegner received her PhD in Chemistry from the University of Chicago (2005-2010), followed by postdoctoral training at the Max Planck Institute for Intelligent Systems and the University of Heidelberg (2011-2015). She served as an Independent Group Leader at the Max Planck Institute for Polymer Research (2016-2020) before joining the University of Münster as a Full Professor in 2019. Her research program centers on the spatiotemporal control of cell-material and cell-cell interactions using visible light. This innovative approach enables non-invasive remote control over cell adhesions, self-assembly of cells into multicellular architectures, regulation of interactions with synthetic materials, and the study of underlying biological processes. Her work bridges multiple disciplines including synthetic biology, optogenetics, and tissue engineering, with specific focus areas on light-controlled minimal cellular systems, photoswitchable cell-cell interactions, and engineering designer biofilms with light. Analysis of her recent publications reveals a strong focus on light-controlled synthetic biology, with particular emphasis on developing tools for precise spatial and temporal control of cellular behaviors. Her work spans from fundamental studies of cell adhesion and motility to applications in tissue engineering and synthetic cell communities, demonstrating consistent innovation in using light as a non-invasive control mechanism for cellular processes. ERC Consolidator Grant (2024) for 'LIGHTHOUSE - Light as a signal for nonchemical cell-to-cell communication' ERC Starting Grant (2018) for 'ARTIST - Artificial cell-cell interactions for light switchable cell organization' Young Leaders in Science Program (2016) by the Schering Foundation MaxSynBio Independent Group Leader position (2015) Alexander von Humboldt Postdoctoral Fellowship (2012) Prof. Wegner actively mentors numerous PhD students and postdoctoral researchers in her lab at the University of Münster. Her research is supported by multiple grants including ERC funding and foundation support. She has established a strong research program that bridges synthetic biology, cell biology, and materials science, with applications in tissue engineering and synthetic cell communities. The Wegner Lab at the University of Münster comprises a multidisciplinary team of postdoctoral researchers, PhD students, and technical staff working at the intersection of cell biology, synthetic biology, and materials science. The lab maintains strong collaborations with the Max Planck Society and participates in research networks such as CRC 1348, focusing on developing light-controlled systems for engineering synthetic cells and multicellular architectures with precise spatial and temporal control.

Pau Formosa-Jordanمشاهده پروفایل

استاد

• Plant Developmental Biology
• Multicellular Dynamics
• Pattern Formation in Plants
• +۴ مورد دیگر

Dr. Pau Formosa-Jordan is a Group Leader in the Department of Plant Developmental Biology at the Max Planck Institute for Plant Breeding Research in Cologne, Germany. He leads a multidisciplinary research group that combines theoretical and experimental approaches to understand multicellular dynamics in plant development. His work spans mathematical modeling, microscopy, and quantitative image analysis to study cellular pattern formation and developmental transitions in plants. Dr. Formosa-Jordan's educational background is in physics, having earned his Ph.D. with Cum Laude distinction from the University of Barcelona. He completed postdoctoral research at the Sainsbury Laboratory, University of Cambridge, working with the Locke, Jönsson, and Meyerowitz groups. His research has been recognized with several awards, including the Herchel Smith Fellowship and the XIX Premi Claustre de Doctors de la Universitat de Barcelona. His research focuses on understanding how multicellular dynamics drive plant developmental processes at different scales, from single-cell resolution to the tissue and whole-plant level. His group primarily studies Arabidopsis thaliana , investigating cellular patterning in tissues such as the leaf and sepal epidermis, and the dynamics of gene expression during the floral transition in the shoot apical meristem. His work integrates mathematical modeling with experimental approaches to uncover the quantitative principles underlying these complex biological processes. Analysis of Dr. Formosa-Jordan's recent publications reveals a strong focus on the intersection of developmental biology, mathematical modeling, and quantitative image analysis. His work frequently addresses fundamental questions about pattern formation in plants, the dynamics of transcription factors, and the role of environmental signals in modulating developmental processes. A recurring theme across his publications is the use of Arabidopsis thaliana as a model system to uncover general principles of multicellular dynamics in plant development. Herchel Smith Fellowship, University of Cambridge XIX Premi Claustre de Doctors de la Universitat de Barcelona Post-Doctoral Research Associate at Queens' College, Cambridge Dr. Formosa-Jordan actively mentors several students and postdocs in his lab, including PhD students and postdoctoral researchers with backgrounds in physics, biology, and engineering. His collaborative work with the Coupland group at the MPIPZ focuses on understanding the floral transition in Arabidopsis . The lab maintains strong connections with both theoretical and experimental research groups worldwide, reflecting the interdisciplinary nature of his work. His research group utilizes advanced imaging platforms and computational tools to study plant development. They have developed specialized software for image analysis and modeling of developmental processes, which are available through their website. The group's work has significant implications for understanding how plants adapt their development to environmental conditions, with potential applications in plant breeding and agriculture.

Vasily Zaburdaevمشاهده پروفایل

استاد

• Theoretical biophysics
• Statistical physics
• Non-equilibrium phenomena
• +۵ مورد دیگر

Professor Vasily Zaburdaev is a Principal Investigator leading the Department of Immunophysics at the Max Planck Center for Physics and Medicine, which is affiliated with Friedrich-Alexander University Erlangen-Nuremberg. His research group develops theoretical models to understand complex biological phenomena and their impact on disease, with expertise in theoretical biophysics, statistical physics, and numerical methods. His research spans several interconnected areas: Bacterial biofilms as complex materials, focusing on their mechanical properties and wound healing capabilities Immunophysics, studying how physical interactions govern immune cell behavior and response to pathogens Statistical physics of active systems, developing new theoretical approaches for understanding biological processes outside thermal equilibrium Zaburdaev's work combines theoretical modeling with close collaboration with experimental groups, utilizing approaches from stochastic processes and continuum theory of active hydrodynamics. His research has significant implications for understanding organizational principles that operate across various biological scales, from chromatin in the nucleus to multicellular aggregates. His recent publications demonstrate a strong focus on cellular organization, cytoplasmic dynamics, and the physical mechanisms governing biological systems. The research shows how concepts from statistical physics can reveal analogies and general behaviors in biologically diverse systems. Scientific Recognition While specific awards aren't listed in the provided information, Zaburdaev's research has been published in high-impact journals including Nature Communications, Physical Review Letters, and Nature Cell Biology, indicating significant recognition in his field. Academic Service Professor Zaburdaev is actively involved in teaching, offering courses such as "Stochastic Models for Life Sciences" and "Physics and biology of active systems" at the university level. His commitment to education complements his research activities, helping to train the next generation of scientists working at the intersection of physics and biology. Research Infrastructure His department is part of the Max Planck Center for Physics and Medicine, which includes various core facilities such as the Core Facility In-vivo Model Systems, Core Facility Microscopy, and Core Facility Lab-on-a-Chip, providing comprehensive research infrastructure for interdisciplinary work.

Tal Daganمشاهده پروفایل

استاد

• Microbial Evolution
• Plasmid Genetics
• Horizontal Gene Transfer
• +۳ مورد دیگر

Prof. Dr. Tal Dagan is a Professor at the Christian-Albrechts-University of Kiel, Germany, within the Biology Center. Her research focuses on microbial evolution, plasmid dynamics, horizontal gene transfer, and bacterial symbiosis. Education: Habilitation in Microbiology (2011, Heinrich-Heine-University Düsseldorf), Ph.D. in Molecular Evolution (2005, Tel-Aviv University), M.Sc. & B.Sc. in Molecular Evolution and Biology (Tel-Aviv University). Her research explores the evolutionary mechanisms of plasmids, antibiotic resistance gene transfer, and microbial symbiosis in marine and plant-associated systems. She investigates how genetic elements like plasmids evolve under environmental pressures and contribute to bacterial adaptability. Recent publications highlight computational tools for DNA duplication detection, plasmid fitness optimization through toxin-antitoxin systems, and the role of natural transformation in cyanobacteria. Her work bridges theoretical models with experimental validation in microbial genomics. Grants from collaborative projects like CRC 754, CRC 1182, and SPP 2002 support her research. She leads a multidisciplinary team analyzing microbial interactions in extreme environments and synthetic biology applications.

Simon Magesمشاهده پروفایل

استاد پژوهشی

• Spatial Omics
• Bioinformatics
• High-Dimensional Data Analysis
• +۳ مورد دیگر

Dr. Simon Mages serves as Group Leader at the Gene Center and Department of Biochemistry, Ludwig Maximilians University Munich (LMU), within the Faculty of Medicine. His research bridges bioinformatics, high-performance computing, and theoretical physics to develop computational frameworks for spatial omics data analysis. Previously, he held positions as Scientist at LMU (2021-2022), Visiting Scientist at the Broad Institute of MIT and Harvard (2020-present), and Research Scientist at Siemens Corporation (2019). His research focuses on the physics of high-dimensional biological data , specifically developing methods to analyze cellular dynamics in joint position-internal state spaces using spatial omics. Key areas include spatial transcriptomics, single-cell data integration, and physics-inspired algorithm development. The Mages Lab collaborates extensively with clinical researchers to translate computational insights into biological understanding, particularly in cancer progression and tissue organization. Analysis of his publication record reveals a strong trajectory from theoretical physics ( 2015-2017 lattice QCD work ) to computational biology ( 2022-present spatial omics leadership ). His recent work demonstrates expertise in algorithm development (TACCO, SlideCNA), multi-omics integration, and clinical applications in oncology. The publications consistently emphasize scalable computational frameworks and physical modeling approaches. Selected scientific awards: German Research Foundation (DFG) Research Fellowship (2020-2022) Studienstiftung des Deutschen Volkes PhD Fellowship (2012-2015) Studienstiftung des Deutschen Volkes Scholarship (2008-2011) Mages advises doctoral researchers including Antonia Eicher and collaborates with major institutions like the Broad Institute. His lab develops open-source tools (BoReMi) and participates in high-impact consortia such as the Regev Lab collaborations. Current research integrates physics-based modeling with cutting-edge spatial technologies to decode multicellular functional units in cancer and tissue organization. The Mages Lab operates within LMU's BioSysM infrastructure at Butenandtstraße 1, leveraging high-performance computing resources for large-scale biological data analysis. The group maintains strong ties with both computational physics (through prior Jülich Supercomputing Centre work) and clinical research communities.