جستجوی استاد راهنمای دانشگاهی

• Immunology
• Genomics
• Multiomics Analysis
• +۳ مورد دیگر

Calliope Dendrou is an Associate Professor in Clinical Pathology and Inflammation at the Kennedy Institute of Rheumatology (KIR), University of Oxford, leading the Immune Disease Multiomics Laboratory. She previously held a Wellcome & Royal Society Sir Henry Dale Fellowship at the University of Oxford’s Centre for Human Genetics before joining KIR in 2023. Her research focuses on immune disease mechanisms using multiomics approaches, including genomic profiling to identify therapeutic targets across tissues and immune-mediated diseases. She co-leads large-scale projects like the Oxford-J&J Cartography Consortium and the Chan Zuckerberg Initiative’s LEGACY Network, and teaches on the MSc in Genomic Medicine program. Educational Background: BSc (Biology, Imperial College London, 2005; Forbes Memorial Medal Winner); PhD in Infection & Immunity (University of Cambridge, 2010). Postdoctoral training at the Weatherall Institute of Molecular Medicine under Prof. Lars Fugger. Research interests include immunogenetics, cytokine signaling pathways, drug repositioning, and cross-disease pathophysiology. Her work integrates single-cell and spatial transcriptomics to dissect immune-cell interactions in diseases like rheumatoid arthritis, inflammatory bowel disease, and celiac disease. Recent articles highlight her contributions to understanding vaccine adjuvant responses, Th17 cell roles in spondyloarthritis, and immune-epithelial networks in celiac disease. Collaborations emphasize multi-omic data analysis (e.g., Panpipes pipeline) and translational studies toward precision medicine. Awards: Forbes Memorial Medal (BSc), Wellcome & Royal Society Sir Henry Dale Fellowship. Leadership roles include Equality, Diversity, and Inclusion Champion and 'Single-Cell & Spatial Omics for Precision Medicine' Module Lead. Lab & Teams: Immune Disease Multiomics Lab at KIR. Active in collaborative initiatives such as the LEGACY Network, focusing on large-scale immune profiling in ancestrally diverse populations.

Vitaly Kheyfetsمشاهده پروفایل

دانشیار

• Pulmonary Arterial Hypertension
• Critical Care Medicine
• Pediatric Cardiology
• +۴ مورد دیگر

Vitaly Kheyfets, PhD, serves as Associate Professor in the Department of Pediatrics-Critical Care Medicine at the University of Colorado Anschutz Medical Campus School of Medicine, where he directs research at the intersection of pediatric critical care and cardiopulmonary pathophysiology with emphasis on pulmonary arterial hypertension (PAH). His primary research focuses on right ventricular adaptation to pulmonary hypertension, utilizing machine learning-driven multi-omics analysis to identify disease biomarkers and molecular networks. He pioneers computational fluid dynamics approaches for hemodynamic modeling in congenital heart conditions like Glenn physiology, while also investigating sleep oscillatory patterns as neurodegenerative biomarkers. His methodology integrates proteomics, spatial transcriptomics, and pressure waveform analysis to dissect vascular remodeling mechanisms. Publication trends reveal a strong emphasis on translating computational models into clinical applications for PAH prognostication, with recent work developing AI-cooperative diagnostic platforms and characterizing microvascular changes in the right ventricle. Cross-disciplinary collaborations span proteomics, imaging, and sleep neuroscience, demonstrating consistent innovation in both pulmonary hypertension and neurodegenerative disease biomarker discovery.

Manuel Kleinerمشاهده پروفایل

دانشیار

• Host-Microbe Interactions
• Microbial Ecology
• Metaproteomics
• +۷ مورد دیگر

Manuel Kleiner is an Associate Professor in the Department of Plant and Microbial Biology at North Carolina State University. His research focuses on metabolic and physiological interactions in host-microbe systems, microbial ecology, and the application of metagenomics and high-resolution mass spectrometry to study complex microbiota-host relationships. Research Highlights: Development of metaproteomic techniques to quantify protein expression, analyze community structure via biomass contributions, and track isotope ratios to understand nutrient flow between hosts and microbiota. Creator of the "transductomics" approach to detect horizontal gene transfer via viral transduction in intestinal systems. Collaborates with researchers such as Theriot, Sartor, Sheikh, Ziegler, and Gonzalez. Recent Trends: His 2025 publications emphasize gut microbiome dynamics, maize root-microbe interactions, transplantation biology, and advancements in metaproteomic methodologies. Key themes include dietary impacts on microbiota, stable isotope probing, and synthetic microbial communities for plant and human health. Laboratory Tools: The Kleiner Lab utilizes quantitative metagenomics, high-resolution mass spectrometry, and computational modeling to dissect functional interactions in symbiotic systems across diverse environments, from marine organisms to agricultural crops.

Mohsen Yoosefzadeh Najafabadiمشاهده پروفایل

استادیار

• Dry Bean Breeding
• Computational Biology
• Omics-Based Selection
• +۵ مورد دیگر

Dr. Mohsen Yoosefzadeh Najafabadi is an Assistant Professor in the Department of Plant Agriculture at the University of Guelph, Ontario Agricultural College. He holds a PhD in Plant Breeding from the University of Guelph (2022), following M.Sc. and B.Sc. degrees from the University of Tehran. His research focuses on dry bean breeding, computational biology, and integrating omics technologies to enhance crop resilience and productivity. Key areas include developing stress-tolerant dry bean varieties, leveraging remote sensing for trait prediction, and optimizing genomic selection methods. He leads the Dry Bean Breeding & Computational Biology Program and has contributed to over 30 peer-reviewed publications since 2017. Education : PhD, Plant Breeding, University of Guelph (2022) M.Sc., University of Tehran B.Sc., University of Tehran Research interests emphasize computational tools development (e.g., AllInOne preprocessing framework), omics-based selection strategies, and non-Mendelian heredity mechanisms. His lab combines machine learning with field phenotyping to address agricultural challenges such as disease resistance and climate adaptation. Collaborative projects include soybean cold stress analysis and cannabinoid profile prediction in cannabis. Publications span genomic approaches to crop improvement, remote sensing applications, and transcriptomic studies. He teaches courses in plant breeding methodologies and actively engages in technology transfer initiatives. Lab activities include developing high-yielding dry bean cultivars resistant to biotic/abiotic stresses and advancing data-driven pipelines for crop breeding. Future work aims to synergize AI with multi-omics data to enhance crop resilience in diverse environments.

Jonathan Weissmanمشاهده پروفایل

استاد

• Protein Folding
• Systems Biology
• Genomics
• +۶ مورد دیگر

Jonathan Weissman is a Professor of Biology at the Massachusetts Institute of Technology (MIT) and a Member of the Whitehead Institute. He is also an Investigator of the Howard Hughes Medical Institute and the Landon T. Clay Professor of Biology. His research spans protein folding mechanisms, ribosome profiling, CRISPR-based tools (CRISPRi/a), and genetic interaction mapping. Whitehead Institute Member MIT Professor HHMI Investigator Co-founder, Maze Therapeutics & KSQ Therapeutics Research Interests focus on: Protein folding in cellular contexts Endoplasmic reticulum (ER) function and stress responses Genome-wide CRISPR screening for gene regulation High-density genetic interaction maps in mammals Mitochondrial protein targeting and quality control Epigenomic engineering with synthetic tools Scientific Awards include: Protein Society Irving Sigal Young Investigator Award (2004) Raymond & Beverly Sackler Prize (2008) National Academy of Sciences election (2009) NAS Award for Scientific Discovery (2015) Genetics Society of America Ira Herskowitz Award (2020) Labs & Collaborations : Leads the Weissman Lab at MIT/Whitehead Institute, co-leads the Laboratory for Genomic Research with GlaxoSmithKline, and chairs the Stowers Institute Scientific Advisory Board.

Marylyn D Ritchieمشاهده پروفایل

استاد

• Computational Genomics
• Bioinformatics
• Pharmacogenomics
• +۸ مورد دیگر

Marylyn D Ritchie, PhD, is the Edward Rose, M.D. and Elizabeth Kirk Rose, M.D. Professor at the Perelman School of Medicine, University of Pennsylvania. She concurrently serves as Director of the Institute for Biomedical Informatics, Vice President for Research Informatics for the University of Pennsylvania Health System, Director of the Division of Informatics in the Department of Biostatistics, Epidemiology, and Informatics, and Vice Dean of Artificial Intelligence and Computing. Education: BS in Biology, University of Pittsburgh at Johnstown, 1999 MS in Applied Statistics, Vanderbilt University, 2002 PhD in Statistical Genetics, Vanderbilt University, 2004 Research Interests Dr Ritchie’s work integrates computational genomics , bioinformatics , pharmacogenomics , and systems genomics to advance precision medicine. She develops statistical and machine-learning approaches to dissect epistasis , genetic epidemiology , and evolutionary computation in large-scale biobanks, with a special focus on cardiovascular disease and Alzheimer’s disease . Her group is also pioneering translational informatics methods that incorporate social determinants of health and fairness metrics into AI-driven clinical decision support. Publication Trends In 2025 alone, Dr Ritchie co-authored more than fifteen high-impact studies spanning vision-language models for 3D CT , multi-omics Alzheimer’s risk prediction , fairness in neuroimaging AI , ancestry-specific pharmacogenomics , and cloud-based polygenic risk score platforms . The collective work highlights a shift from single-omics discovery to integrative, equitable, and clinically actionable models across diverse ancestries. Awards & Honors While specific named awards were not detailed in the text, Dr Ritchie’s endowed professorship and multi-institutional leadership roles signify sustained recognition. Grants & Advising Dr Ritchie leads large NIH, foundation, and industry-funded initiatives that support interdisciplinary teams of postdocs, graduate students, and data scientists. Her lab actively mentors trainees from UPenn’s Cell and Molecular Biology and Genomics and Computational Biology graduate groups. Laboratories & Teams She directs the Ritchie Lab (ritchielab.org), which develops open-source visualization tools such as PhenoGram , PheWAS-View , and Synthesis-View for genome-wide and phenome-wide data exploration. The lab operates within the Institute for Biomedical Informatics and collaborates closely with the Penn Medicine BioBank and multiple clinical departments to translate big-data discoveries into precision medicine workflows.

• Autism Genetics
• Genetic Architecture
• Copy Number Variants
• +۵ مورد دیگر

Lauren Weiss, PhD is a Professor of Psychiatry at the University of California, San Francisco (UCSF) School of Medicine and a faculty member at the UCSF Weill Institute for Neurosciences. Her research focuses on understanding the genetic architecture of autism spectrum disorder through genome-wide genetic data analysis and human induced pluripotent stem cell (iPSC) models. Dr. Weiss's laboratory investigates the genetic mechanisms by which DNA variants influence autism risk, examining questions about copy number vs. SNP variation, rare vs. common variation, gene-sex interaction, gene-gene interaction, and gene-environment interaction. Her team uses rich genetic datasets to identify susceptibility loci and the physiological pathways these risk loci implicate. Additionally, they employ iPSC models to study known mutations or copy number variants predisposing to autism, first identifying the effects of genetic risk variants and then determining whether these effects can be modified at the cellular level by environmental or pharmacological agents. Analysis of Dr. Weiss's recent publications reveals a strong focus on sex differences in autism genetics, the role of specific copy number variants (particularly 16p11.2 and 22q11.2), maternal environmental factors during pregnancy, and the integration of multi-omics data to understand neurodevelopmental pathways. Her work bridges basic genetic research with potential clinical applications for improving understanding, prevention, diagnosis, and treatment of autism and related traits. Dr. Weiss has secured significant research funding as Principal Investigator on multiple NIH grants, including R01MH114924 (Decoding the Genetics of Sexual Dimorphism in Autism Spectrum Disorders), R01MH107467 (Utilizing eQTL networks to gain biological insight into multigenic CNVs), and DP2OD007449 (Dissecting Epistasis and Pleiotropy in Autism towards Personalized Medicine). Her laboratory offers research opportunities for students interested in analytical genetics projects related to gene-environment effects, gene-sex effects, gene-gene effects, and the relationship between ASD and brain size. Dr. Weiss actively collaborates with numerous researchers across institutions, particularly on large-scale genomic studies of autism and other neurodevelopmental disorders. Her work has contributed significantly to our understanding of the complex genetic architecture underlying autism spectrum disorder and related conditions.

Karl-Heinz Wagnerمشاهده پروفایل

استاد

• Oxidative stress and DNA stability
• Molecular nutrition and phytochemicals
• Dietary antioxidants and aging
• +۵ مورد دیگر

Karl-Heinz Wagner is Full Professor of Nutrition and Food Quality at the University of Vienna, Faculty of Life Sciences, Department of Nutritional Sciences. He directs an experimental research group investigating how lifestyle factors—diet, specific food components, phytochemicals, physical activity and bioactive non-food compounds—modulate oxidative stress and DNA stability in humans, with emphasis on aging and sarcopenia. He initiated the university-wide “Active Ageing” research platform and coordinates EU projects such as SHIFT2HEALTH. Education & Affiliations: University of Vienna, Faculty of Life Sciences, Department of Nutritional Sciences – Professor and Chair of Nutrition and Food Quality Principal investigator of the Emerging Field “Oxidative Stress and DNA Stability” Head of the “Active Ageing” research platform activeageing.univie.ac.at Research Focus: Prof. Wagner’s group applies state-of-the-art biochemical and molecular techniques to quantify antioxidant compounds, ROS-induced DNA and chromosomal damage, DNA repair capacity and transcriptional regulation of antioxidant defenses. Human intervention trials, cross-sectional cohorts and in-vitro models are used to examine: Impact of plant-based vs. animal-based diets on multimorbidity risk Nitrate-rich beetroot juice effects on microbiome, vascular function and oxidative stress Bilirubin biology and metabolic health in Gilbert’s syndrome High-protein nutrition and resistance training on DNA damage and muscle quality in older adults Microbiota-derived metabolites that enhance CD8 T-cell antitumor immunity after exercise Publication Trends 2023-2025: Recent output demonstrates a strategic shift toward multi-omics integration (metabolomics, lipidomics, proteomics) to dissect diet–microbiome–immune crosstalk and to identify predictive biomarkers of healthy ageing. Papers consistently appear in top-tier journals (Cell, Lancet Healthy Longev, Redox Biol, Mol Nutr Food Res) and embrace large multinational cohorts, randomized controlled trials and mechanistic animal/cellular work. Funding & Networks: Research is mainly funded by the Austrian Science Fund (FWF), National Bank, European Commission (Horizon 2020, Horizon Europe), EU Cross-Border Co-operation and the University of Vienna. A dense national and international partner network ensures continuous biomarker development and knowledge transfer. Student Training & Citizen Science: Prof. Wagner actively involves MSc/PhD students and post-docs in externally funded projects and advertises internships via ERASMUS+. Study participant recruitment portals for projects like SHIFT2HEALTH, NUTRIAGING and bilirubin clinical studies are maintained to engage the public and foster translational impact.

Khashayarsha Khazaieمشاهده پروفایل

استاد

• Cancer Immunology
• Inflammation
• Regulatory T Cells
• +۱۲ مورد دیگر

Khashayarsha Khazaie, Ph.D., is a Professor of Immunology at Mayo Clinic in Phoenix, Arizona, with a primary appointment as a Consultant in the Department of Immunology and a joint appointment in Cancer Biology, Department of Research. He leads a research laboratory focused on cancer immunology, inflammation, and the tumor-microbiota-immune axis, with emphasis on gastrointestinal and gynecological malignancies. Education: Ph.D. in Genetics/Senescence, MRC, National Institute for Medical Research Doctor of Science, University of Paris V, René Descartes BSc (Hons) in Chemistry, Biology, Physics, University of Surrey Postdoctoral Research, CNRS; EMBL; National Institute for Medical Research Research Interests: Dr. Khazaie’s lab investigates regulatory T cells (Tregs), mast cells, circadian rhythms, fibrosis, and microbial-based cancer vaccines. His work explores how immune suppression and chronic inflammation promote tumor growth, particularly in colorectal and endometrial cancers. Key areas include Treg plasticity, epigenetic reprogramming, microbiota-driven carcinogenesis, and the immunology of metastasis. Recent Research Trends: His most recent publications highlight the role of circadian disruption in colon cancer, the therapeutic potential of biomaterial-enhanced Treg immunotherapy, and the use of single-cell and spatial-omics to dissect immune-related diseases. His studies integrate molecular, cellular, and systems-level approaches to understand immune dysregulation in cancer and chronic inflammation. Scientific Leadership: Director, Federation of Clinical Immunology Societies, Mayo Clinic Center of Excellence (2018–present) Associate Editor, Journal for ImmunoTherapy of Cancer (2013–present) Editorial Board, Cancer Immunology Research (2012–present) Associate Editor, Tumor Immunity, Frontiers in Immunology and Oncology (2011–present) Visiting Professor, University of Regensburg (2016); Université Paris-Est Créteil (2016) Grants and Advising: Dr. Khazaie has led multiple NIH-funded projects, including studies on Parvimonas micra-induced carcinogenesis, β-catenin in Treg expansion, and circadian disruption in colon cancer. He mentors researchers and contributes to the education of future physicians and scientists in immunology and cancer biology. His lab collaborates with Biomed Valley Discoveries and MD Anderson on clinical trials of bacterial vaccines for metastatic cancer. Laboratory and Collaborations: His laboratory operates at the interface of basic and translational science, using mouse models, clinical specimens, and multi-omics technologies. He is deeply involved in collaborative research networks, particularly in cancer immunology and microbiota studies.

Marios Georgakisمشاهده پروفایل

پژوهشگر

• Biomedical Neuroscience
• Cerebrovascular Disease
• Stroke
• +۷ مورد دیگر

Dr. Marios Georgakis is a Clinician-Scientist and Junior Group Leader at the Institute for Stroke and Dementia Research (ISD) at Ludwig-Maximilians-Universität München (LMU Munich). He also serves as a Visiting Scientist at the Broad Institute of MIT and Harvard and is completing his clinical residency in Neurology at LMU University Hospital. As Principal Investigator of the Georgakis Lab, he leads a research team focused on developing precision medicine approaches for cerebrovascular diseases. Education: Medical studies (M.D.): Medical School, National and Kapodistrian University of Athens, Greece (2009-2015) Master studies (M.Sc.): Molecular Physiology (Neurosciences), National and Kapodistrian University of Athens, Greece (2015-2017) Doctoral studies (D.Sc.) in Epidemiology, National and Kapodistrian University of Athens, Greece (2015-2019) Doctoral studies (Ph.D.) in Graduate School of Systemic Neurosciences (GSN), LMU Munich, Germany (2017-2020) Dr. Georgakis' research focuses on leveraging big data from epidemiological studies and human biobanks to develop precise and personalized preventive and therapeutic strategies for cerebrovascular diseases. His work spans biomedical neuroscience with particular emphasis on cerebrovascular disease, stroke, atherosclerosis, cerebral small vessel disease, multi-omics, data science, epidemiology, and population genetics. He employs innovative bioinformatic tools including genome-wide association studies, Mendelian randomization, multi-omics integration, single-cell transcriptomics, spatial transcriptomics, and machine learning to discover causal mechanisms, identify therapeutic targets, develop risk stratification tools, and create accurate biomarkers for cerebrovascular diseases. His laboratory has established the AtherOMICS biobank for human atherosclerotic plaque samples and developed computational pipelines for big data analyses. Recent publication trends show a strong focus on genetic architecture of stroke, inflammatory pathways in cerebrovascular disease, and development of polygenic risk scores for clinical application. Scientific Awards: Emmy Noether Independent Group Leader Award, German Research Foundation (DFG), 2023 Early Career Achievement Award, CHARGE Consortium, 2023 Fellow of the Hertie Network of Excellence in Clinical Neuroscience, 2023 Clinician-Scientist Fellow of the Excellence Munich Cluster for Systems Neurology (SyNergy), 2023 Walter-Benjamin Fellowship for postdoctoral research by German Research Foundation (DFG), 2021-2022 Dr. Georgakis actively mentors a diverse team of 12 current students and postdocs including PhD students, MD students, and clinician scientists, with several alumni who have completed their training in his lab. His research is supported by multiple grants including the Emmy Noether program from the German Research Foundation, focusing on multi-omics characterization of immune mechanisms driving human atheroprogression, dissecting cerebrovascular atherosclerosis with population genetics, and developing personalized biomarkers using deep learning. The Georgakis Lab operates two main research platforms: the AtherOMICS Biobank for human atherosclerotic plaque samples and the Big Data Lab for computational analyses. These platforms enable his team to conduct deep phenotyping of human atherosclerosis, develop in vivo diagnostics, discover therapeutic targets, and create personalized diagnostic and risk prediction tools for cardiovascular diseases.

Mariaelena Pierobonمشاهده پروفایل

دانشیار

• Biomedical Research
• Medical Proteomics
• Precision Medicine
• +۳ مورد دیگر

Mariaelena Pierobon is an Associate Professor at George Mason University's School of Systems Biology, affiliated with the Institute for Advanced Biomedical Research and the Center for Applied Proteomics and Molecular Medicine (CAPMM). Her research focuses on precision medicine for cancer patients, integrating translational studies and clinical trials with emphasis on metastatic disease and tumor microenvironment analysis. MD, University of Padova (Italy), School of Medicine MPH, George Mason University Her work leverages in vitro models and patient-derived specimens with state-of-the-art technologies to explore cancer dynamics and develop tailored therapies. Recent projects include proteogenomic profiling of breast and ovarian tumors, KRAS mutation targeting, and spatial heterogeneity mapping in gynecologic cancers. Scientific trends in her publications include precision oncology, signaling pathway inhibition in KRAS-mutant cancers, tumor microenvironment analysis, and multi-omic diagnostics for therapeutic response prediction. Fulbright Scholar (2019) Pierobon collaborates with clinical teams using reverse phase protein arrays (RPPA) and laser capture microdissection to dissect molecular mechanisms in pancreatic, breast, and ovarian cancers. Her lab contributes to databases like the Side-Out Foundation Metastatic Breast Cancer portal for open-access multi-omic research.

Rod Snowdonمشاهده پروفایل

استاد

• Plant Breeding
• Genomics
• Agricultural Science
• +۴ مورد دیگر

Rod Snowdon is a Professor and Chair of Plant Breeding at Justus-Liebig-Universität Giessen since 2013. He holds honorary positions at The University of Queensland, Southwest University, and Hunan Agricultural University, and leads the IRTG 2843 international research training group. Education: PhD in Biometry and Population Genetics (1997-2001), MSc in Plant Genetics (1991), BSc in Biology (1989) Key Roles: Editor-in-Chief of Theoretical and Applied Genetics, member of DFG Review Board, and scientific advisor for Julius Kühn Institute His research focuses on genomic and genetic dissection of complex traits in crops like oilseed rape, sorghum, wheat, barley, and faba bean. He specializes in trait prediction using multi-omics data and analyzing structural genome variation's impact on quantitative traits and crop evolution. Recent publications highlight his work in genotype-environment interactions , faba bean genome analysis , sorghum conservation breeding , and canola establishment strategies . Trends include crop adaptation to environmental stress, genomic resource development, and sustainable breeding methodologies. Honors: Honorary Doctorate from Iasi University, OECD Fellowship Leadership: Chair of Multinational Brassica Genome Project (2013-2015), Speaker of IRTG 2843 As Editor-in-Chief and advisory board member, he shapes global plant breeding research directions. His lab integrates molecular techniques with population genetics to enhance crop resilience and productivity.

• Computational Genomics
• Single-Cell Genomics
• Immunology
• +۳ مورد دیگر

Dr. Stephen Sansom serves as Associate Professor and Group Leader of the Computational and Single Cell Genomics Group at the University of Oxford's Kennedy Institute. His work bridges computational biology with immunology to decode inflammatory disease mechanisms through advanced genomic approaches. His academic foundation includes a BSc (Hons) in Biochemistry from the University of Dundee (2001) followed by a DPhil in Developmental Biology through the Wellcome Trust 4-year PhD programme at the University of Cambridge. Postdoctoral research at the Gurdon Institute with Dr. Rick Livesey established his expertise in genomic analysis of neural development. Dr. Sansom's research centers on computational genomics of immune processes, particularly central tolerance mechanisms and inflammatory disorders. His group pioneers single-cell genomic methodologies to dissect cellular heterogeneity in conditions like inflammatory bowel disease, rheumatoid arthritis, and atherosclerosis. Key innovations include developing frameworks for analyzing promiscuous gene expression in thymic epithelia and deconvoluting monocyte responses in immune-mediated diseases through collaborative projects with experimental immunologists. Analysis of his recent publications reveals dominant themes in macrophage biology during atherosclerosis progression, B/T cell dynamics in viral infections (including influenza and COVID-19), and stromal cell contributions to joint destruction in arthritis. His work consistently identifies novel cellular states and molecular networks driving pathogenesis, with strong emphasis on translational relevance for therapeutic targeting. Supported initially by an MRC Career Development Fellowship in Chris Ponting's CGAT program, Dr. Sansom now directs the Computational Genomics team he established at the Kennedy Institute in 2014. His collaborative model integrates computational expertise with wet-lab immunology across multiple Oxford research groups. The Sansom Group operates as the Computational and Single Cell Genomics Group within the Kennedy Institute, maintaining specialized pipelines for high-dimensional genomic data analysis. Current efforts focus on scaling single-cell multi-omics approaches to track immune cell evolution during chronic inflammation and infection.

Jennifer E. Phillips-Creminsمشاهده پروفایل

دانشیار

• 3D Genome Organization
• Chromatin Biology
• Neurogenetics
• +۵ مورد دیگر

Jennifer E. Phillips-Cremins, Ph.D. , is an Associate Professor of Genetics and Bioengineering at the University of Pennsylvania, where she leads the Laboratory of Chromatin and Spatial Neurobiology. A member of the Penn Epigenetics Institute and NIH 4D Nucleome Consortium, her research investigates how three-dimensional chromatin organization governs neural specification, synaptic plasticity, and disease pathogenesis. Her lab integrates 3D genome mapping, single-cell imaging, and computational tools to dissect chromatin-synapse communication in Alzheimer's disease, fragile X syndrome, and schizophrenia. Education : B.S. in Chemical Engineering (Clarkson University, 1999), Ph.D. in Biomedical Engineering (Georgia Tech, 2007) Postdoctoral Training : University of Massachusetts (Dekker Lab) and Emory University (Corces Lab, 2008-2013) Her lab has developed groundbreaking technologies including LADL for optogenetic chromatin control, FISHnet for single-cell spatial genomics, and MASTR-seq for repeat expansion analysis. Key discoveries demonstrate that cohesin-mediated loops regulate replication origins and synaptic gene expression, while BREACHes link repeat instability to neurodevelopmental defects. Scientific Recognition : NIH Pioneer Award (2021) NSF CAREER Award (2020) Chan-Zuckerberg Neurodegenerative Disease Awardee (2020) New York Stem Cell Foundation Robertson Investigator (2015-2020) Mentorship : Creator of the SEEDs program for undergraduate/post-baccalaureate training, with 100% of alumni pursuing advanced scientific degrees. Her lab currently trains 3 SEEDs scholars and advises graduate students in Cell and Molecular Biology, Neuroscience, and Bioengineering programs.

Jennifer Lachowiecمشاهده پروفایل

دانشیار

• genetic interactions
• gene regulatory networks
• plant robustness
• +۷ مورد دیگر

Jennifer Lachowiec serves as Associate Professor in the Department of Plant Sciences and Plant Pathology at Montana State University's College of Agriculture. Her research program focuses on understanding genetic robustness in plants through interdisciplinary approaches spanning quantitative genetics, genomics, and molecular biology. She teaches foundational courses in biometry and research design while leading a technology-driven laboratory that utilizes unoccupied aerial systems for large-scale phenotyping. Educational background: Ph.D. in Molecular and Cellular Biology, University of Washington (2014) B.S. in Genetics and Anthropology, University of Wisconsin - Madison (2008) Her research centers on predicting phenotypes from genetic sequences with emphasis on plant robustness—the capacity to maintain phenotypes despite genetic mutations and environmental fluctuations. The Lachowiec Lab integrates quantitative genetics, molecular biology, and evolutionary approaches to study gene regulatory networks and genetic interactions. A key innovation involves deploying UAVs and automated imaging systems to quantify robustness across plant populations, enabling high-throughput analysis of crop resiliency traits. This work bridges fundamental genetic mechanisms with practical agricultural applications for developing climate-resilient crops. Recent publications (2022-2025) reveal consistent focus on UAV-based phenotyping, polyploid genomics, and crop stress adaptation. Key trends include development of robust phenomic databases, genetic dissection of barley malting traits, herbicide resistance mechanisms in aquatic weeds, and metabolic responses to environmental stress. The work demonstrates strong translational impact through USDA-funded projects addressing nitrogen-efficient camelina production and heat stress tolerance in cereal crops. Scientific recognition includes: Nominated for USDA Teaching Award (2023) Phi Kappa Phi Anna K. Fridley Award (2023) College of Agriculture Teaching Award of Merit (2023) Transformative Teaching Award (2022) Open Education Resources Adoption Award (2021) Research is supported by multiple USDA NIFA and DOE grants including 'Enhancing Camelina Oilseed Production with Minimum Nitrogen Fertilization,' 'Uncovering developmental mechanisms to sustain grain number during heat stress,' and 'Genetic controls for crop microbiome recruitment.' Dr. Lachowiec serves on the North American Plant Phenotyping Network DEI Committee and has organized outreach events including MSU Family Science Day. Her laboratory, located in the Plant Bioscience Building on traditional Amskapii Pikani, Apsaalooke, Tsétsêhéstâhese, and Seliš lands, maintains specialized facilities for UAV-based phenotyping and growth room imaging systems to advance plant robustness research.