Mouse Tracking Studies Professors and Supervisors

Elaine Dzierzakمشاهده پروفایل

استاد

Max Planck Institute for Research on Collective GoodsGermany

Academic Profile Professor Elaine Dzierzak holds the Chair of Haematologic Regeneration at the University of Edinburgh since 2013. Previously, she served for 17 years at Erasmus University Medical Center in Rotterdam, where she was Professor of Developmental Biology (1996-2013) and Director of the Erasmus MC Stem Cell Institute (2008-2013). Her earlier career includes positions at the National Institute for Medical Research in London and postdoctoral training at MIT Whitehead Institute. Research Focus Professor Dzierzak leads groundbreaking research in developmental haematopoiesis, with particular expertise in: Hematopoietic stem cell origin and development Aorta-gonad-mesonephros (AGM) biology Endothelial-to-hematopoietic transition mechanisms Stem cell microenvironments in embryonic and placental tissues Transcriptional regulation of blood formation Her laboratory has developed innovative 3D imaging approaches to study blood cell emergence in vivo. Honors & Recognition ERC Advanced Grant (2013) NIH Merit Award (2006) NWO VICI Award (2003) Elected EMBO Member (1998) President, International Society for Experimental Hematology (2012) EuroSTELLS Research Award (2005) Professional Engagement Professor Dzierzak serves on editorial boards of leading journals including Cell Stem Cell , Blood , and Immunity . She has chaired international review boards for organizations including the European Science Foundation, NIH, and Leukemia Research Fund.

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Jean F. Jasminمشاهده پروفایل

استادیار

Thomas Jefferson UniversityUnited States

Jean F. Jasmin is an Assistant Professor (Tenure-Track) at Thomas Jefferson University's College of Life Sciences, focusing on molecular mechanisms in pulmonary hypertension, cardiovascular disease, and cancer biology. Her work bridges translational research and therapeutic development. Dr. Jasmin earned her PhD in Physiology from the University of Montreal in 2004, followed by post-doctoral training at Thomas Jefferson University (Cancer Biology, 2007) and Albert Einstein College of Medicine (Molecular Pharmacology, 2006). Her research program investigates: Pulmonary Hypertension: Developing Caveolin-1-mimetic peptides to treat WHO groups I, II, and III pulmonary hypertension through preclinical models Cardiovascular Disease: Elucidating Caveolin-1's role in beta-adrenergic signaling during myocardial infarction and heart failure Cancer Biology: Characterizing CAPER as a biomarker and therapeutic target in triple-negative breast cancer Her publication trends reveal a strategic shift from pulmonary/cardiac molecular pathways (2006-2011) toward cancer mechanisms, with current emphasis on CAPER-targeted therapies for aggressive breast cancer subtypes. Key contributions include establishing Caveolin-1's therapeutic potential in pulmonary hypertension regression and identifying CAPER's nuclear translocation as a cancer progression marker. Scientific recognition includes competitive post-doctoral fellowships: Thomas Jefferson University Cancer Biology Fellowship (2007) Albert Einstein College of Medicine Molecular Pharmacology Fellowship (2006) Dr. Jasmin's research program demonstrates strong translational focus, with pulmonary hypertension work progressing toward clinical applications and cancer studies developing CAPER-targeted peptides. No student advising or grant details were specified in source materials, though her laboratory likely operates within the Bluemle Life Sciences Building infrastructure.

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Priti Kumarمشاهده پروفایل

دانشیار

Max Planck Institute of Molecular Cell Biology and GeneticsGermany

Virology
Immunology
Gene therapy
+۷ مورد دیگر

Dr. Priti Kumar is an Associate Professor of Infectious Diseases and Microbial Pathogenesis at Yale University School of Medicine. She serves as Director of Graduate Admissions for the BBS Microbiology Track and Director of the Yale Predoctoral Training Program in Virology. Dr. Kumar is also a Chartered Member of the NIH NIAID Study Section on AIDS Discovery And Development Of Therapeutics. Dr. Kumar received her PhD in Immunology from the Indian Institute of Science in 2002, followed by postdoctoral training at Harvard Medical School. She joined Yale University as an Assistant Professor in 2008 and has been advancing innovative research in virology and gene therapy for over 15 years. Her laboratory conducts translational research focused on developing gene therapy and cure-based approaches for RNA viruses including HIV-1, West Nile virus, Japanese encephalitis virus, dengue, and SARS-CoV-2. Key research areas include: Overcoming in vivo biological barriers for therapeutic delivery Development of nucleic acid delivery platforms (siRNA, CRISPRs) Humanized mouse models for HIV research Live-imaging of viral pathogenesis Transvascular delivery of therapeutics to the CNS Analysis of Dr. Kumar's recent publications (2022-2025) reveals a strong focus on HIV therapeutics, SARS-CoV-2 vaccine and treatment development, and innovative approaches to nucleic acid delivery. Her work spans virology, immunology, and translational medicine, with frequent collaborations across Yale departments. As Director of graduate training programs, Dr. Kumar plays a significant role in mentoring the next generation of virologists and immunologists. Her laboratory within the Yale Virology Laboratories provides students with opportunities to work on cutting-edge translational research that bridges basic science and therapeutic development. Dr. Kumar's research has resulted in numerous high-impact publications in journals including Nature, Cell Host and Microbe, PNAS, and Science, demonstrating her significant contributions to the fields of virology and gene therapy.

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Michael Walter Jakowecمشاهده پروفایل

استاد آموزشی

University of Southern CaliforniaUnited States

Michael Walter Jakowec, PhD, serves as Professor of Clinical Pharmacy (Teaching Track) in the Titus Family Department of Clinical Pharmacy at the University of Southern California's School of Pharmacy and Pharmaceutical Sciences, a position he assumed in May 2024. Previously, he held the role of Professor of Research Neurology at USC's Keck School of Medicine. His research centers on molecular mechanisms of neuroplasticity in brain disorders, with emphasis on Parkinson's disease and drug addiction, particularly investigating exercise-induced synaptogenesis and pharmacological interventions for brain repair. Education PhD, University of California, Davis MSc, University of Toronto BSc (Institution unspecified) Postdoctoral Fellow, Columbia University Department of Neurology Postdoctoral Fellow, Yale University Department of Neurology Postdoctoral Fellow, Yale University Department of Molecular Biophysics and Biochemistry Postdoctoral Fellow, University of Southern California Dr. Jakowec's research program investigates neuroplasticity mechanisms in the basal ganglia and prefrontal cortex using rodent models of Parkinson's disease. His laboratory employs diverse methodologies including molecular biology, neuroimaging, and behavioral analysis to study exercise-induced synaptogenesis, astrocyte-neuron interactions, and mitochondrial function. A key translational focus involves bridging basic science findings to clinical applications through collaborations with neurologists and physical therapists. His recent publications (2021-2024) demonstrate consistent emphasis on Parkinson's disease mechanisms and exercise interventions, with growing integration of neuroimaging, molecular biomarkers, and health disparity research. The work reveals how physical activity intensity correlates with cognitive function and brain connectivity, while exploring novel therapeutic targets like mitochondrial peptides and astrocytic transporters. Dr. Jakowec actively mentors undergraduate, Master's, and Doctoral students through laboratory research and classroom instruction. He designs and teaches specialized courses including Comparative Neuropharmacology and Neuropharmacology of Drug Addiction, emphasizing translational pathways from molecular mechanisms to therapeutic development. His educational philosophy centers on training future scientists through hands-on research experiences across the academic spectrum. His laboratory operates within USC's collaborative neuroscience ecosystem, maintaining strong ties with the Department of Neurology, Division of Biokinesiology and Physical Therapy, and Institute for Addiction Sciences. Current projects focus on translating exercise neuroscience findings into clinical practice, particularly through partnerships examining biokinematics and cognitive testing in Parkinson's patients.

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Joakim Bergströmمشاهده پروفایل

پژوهشگر

Uppsala UniversitySweden

Joakim Bergström serves as an Associate Researcher at Uppsala University's Department of Public Health and Care Sciences within the Faculty of Medicine, specifically at the Molecular Geriatrics/Rudbeck Laboratory. He concurrently holds a Research Advisor position at the University Administration's Office of Medicine and Pharmacy. Faculty of Medicine, Uppsala University Department of Public Health and Care Sciences Molecular Geriatrics/Rudbeck Laboratory Office of Medicine and Pharmacy (Research Support Unit) His primary research focuses on alpha-synuclein pathology mechanisms in Parkinson's disease, with particular emphasis on oligomer formation, propagation pathways, and immunotherapeutic interventions. Bergström investigates how alpha-synuclein aggregates interact with cellular components like SNARE proteins and glial cells, and develops antibody-based strategies to mitigate neurodegeneration in transgenic models. Analysis of his 15 most recent publications reveals consistent investigation of alpha-synuclein oligomerization mechanisms, transgenic mouse modeling of Parkinson's symptoms, and therapeutic antibody development. His work spans molecular neuroscience, neuroimmunology, and translational neuropharmacology, with increasing focus on imaging techniques and cross-amyloid interactions in recent years. Bergström actively collaborates with leading researchers in the field including Martin Ingelsson, Veronica Lindström, and Gunilla Westermark, contributing to studies that bridge basic molecular mechanisms with potential clinical applications for synucleinopathies.

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