معرفی
Jean F. Jasmin is an Assistant Professor (Tenure-Track) at Thomas Jefferson University's College of Life Sciences, focusing on molecular mechanisms in pulmonary hypertension, cardiovascular disease, and cancer biology. Her work bridges translational research and therapeutic development.
Dr. Jasmin earned her PhD in Physiology from the University of Montreal in 2004, followed by post-doctoral training at Thomas Jefferson University (Cancer Biology, 2007) and Albert Einstein College of Medicine (Molecular Pharmacology, 2006). Her research program investigates:
- Pulmonary Hypertension: Developing Caveolin-1-mimetic peptides to treat WHO groups I, II, and III pulmonary hypertension through preclinical models
- Cardiovascular Disease: Elucidating Caveolin-1's role in beta-adrenergic signaling during myocardial infarction and heart failure
- Cancer Biology: Characterizing CAPER as a biomarker and therapeutic target in triple-negative breast cancer
Her publication trends reveal a strategic shift from pulmonary/cardiac molecular pathways (2006-2011) toward cancer mechanisms, with current emphasis on CAPER-targeted therapies for aggressive breast cancer subtypes. Key contributions include establishing Caveolin-1's therapeutic potential in pulmonary hypertension regression and identifying CAPER's nuclear translocation as a cancer progression marker.
Scientific recognition includes competitive post-doctoral fellowships:
- Thomas Jefferson University Cancer Biology Fellowship (2007)
- Albert Einstein College of Medicine Molecular Pharmacology Fellowship (2006)
Dr. Jasmin's research program demonstrates strong translational focus, with pulmonary hypertension work progressing toward clinical applications and cancer studies developing CAPER-targeted peptides. No student advising or grant details were specified in source materials, though her laboratory likely operates within the Bluemle Life Sciences Building infrastructure.
