جست‌وجوی استاد و پژوهشگر

Christopher E. Nelsonمشاهده پروفایل

استادیار

• Gene therapy
• Regenerative medicine
• Genome editing
• +۷ مورد دیگر

Christopher E. Nelson is an Assistant Professor in the Department of Biomedical Engineering at the University of Arkansas, College of Engineering. His lab focuses on developing biologically inspired strategies for controlled drug and gene delivery, particularly in the context of gene therapy and regenerative medicine. He is actively supported by the NIH, DoD, and Arkansas Bioscience Institute. Education: Postdoctoral Fellow – Duke University Ph.D. – Vanderbilt University B.S. – University of Arkansas Research Focus: Dr. Nelson’s lab integrates genome editing technologies with targeted delivery systems to address challenges in treating genetic diseases and promoting tissue regeneration. Major themes include CRISPR/Cas9 delivery , gene regulation in wound healing , and safe-harbor genome integration in skeletal muscle. His work spans viral and non-viral delivery vehicles , including lipid nanoparticles and AAV vectors, with a strong emphasis on preclinical validation in models of Duchenne muscular dystrophy and inflammatory disease. Scientific Awards: Controlled Release Society Postdoctoral Fellowship The Hartwell Foundation Postdoctoral Fellowship NIH Pathway to Independence Award (K99/R00) Funding & Support: The Nelson Lab is currently funded by: NIH NIGMS R35 DoD CDMRP DMD IDEA Award Arkansas Bioscience Institute University of Arkansas Engineering & Honors Colleges Lab & Team: The Nelson Lab is a dynamic, interdisciplinary team working at the intersection of gene editing, biomaterials, and regenerative medicine. They regularly present at national conferences such as ASGCT and NCUR, and mentor undergraduate researchers through SURF and Honors College grants.

Laura Soltمشاهده پروفایل

دانشیار

• Autoimmune Disease
• Cancer Immunotherapy
• Immunometabolism
• +۵ مورد دیگر

Laura Solt, Ph.D. is an Associate Professor in the Department of Immunology and Microbiology at the Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology in Jupiter, Florida. She also serves as Associate Dean of the Skaggs Graduate School of Chemical and Biological Sciences. Dr. Solt began her independent research career at Scripps Florida in 2013 and has established herself as a leading researcher in nuclear receptor biology within the immune system. Her research focuses on understanding the biologically relevant roles of nuclear receptors, particularly RORα and REV-ERBs, in the immune system with emphasis on TH17 cell development and autoimmune disease. Her lab employs a multidisciplinary approach combining molecular biology, genetic techniques, and chemical biology coupled with mouse models of autoimmunity and chronic inflammation. Dr. Solt's laboratory has made significant contributions to understanding how nuclear receptors regulate immune cell function, particularly in TH17-mediated inflammation. Her work has demonstrated roles for RORα and REV-ERBs in TH17 cell development and has developed synthetic ligands to these receptors for potential therapeutic applications in autoimmune diseases. Her extensive publication record shows a clear trajectory of research focused on nuclear receptor signaling in immunity, with recent work expanding into applications for cancer immunotherapy, neuroimmunology, and metabolic aspects of immune cell function. Her articles demonstrate expertise in both basic nuclear receptor mechanisms and translational applications. Ruth L. Kirschstein National Research Service Awards (2010-2013) Dr. Solt actively mentors graduate students including Adrianna Wilson (recipient of NIDDK F31 and Scheller Graduate Student Fellowship) and Sarah Mosure (recipient of NIH NRSA F31 award and Wendy Havran award). Her laboratory receives substantial funding from multiple NIH institutes (NIDDK, NCI, NIAID, NIGMS) as well as the Crohn's & Colitis Foundation. Current research directions include investigating the roles of NR2F6 in TH17 cells, exploring RORα function in CD8 T cells, and developing novel nuclear receptor modulators for therapeutic applications.

Xiaoyu Caiمشاهده پروفایل

استادیار

• Lung Regeneration
• Inflammation Resolution
• Aging Biology
• +۵ مورد دیگر

Xiaoyu Cai is an Assistant Professor at the Department of Medicine, Loyola University Chicago, specializing in lung regeneration, aging biology, and stem cell plasticity. Her research focuses on the molecular mechanisms governing alveolar type 2 (AT2) stem cell dynamics during aging and chronic lung diseases. Education: Bachelor of Medicine (Peking University, 2012), Master of Science (Peking University, 2015), PhD in Biology of Aging (USC & Buck Institute, 2021) Key Research Areas: Lung regeneration, inflammation resolution, stem cell aging, 3D organoid cultures Methodologies: Single-cell multiome, mouse genetics, multicellular organoid systems Collaborations: Translational partnerships with clinical teams for bench-to-bedside applications Dr. Cai's recent work explores lineage plasticity in aged lung stem cells, ferroptosis suppression via CRISPR screens, and cellular aging atlases across species. She previously held a postdoctoral position at Genentech Inc. and maintains a professional lab website. Contact: xcai2@luc.edu | Office: CTRE 123

Rachel Carmodyمشاهده پروفایل

دانشیار

• Human Evolutionary Biology
• Nutrition
• Gut Microbiome
• +۳ مورد دیگر

Dr. Rachel Carmody is the Thomas D. Cabot Associate Professor of Human Evolutionary Biology at Harvard University, affiliated with the Faculty of Arts and Sciences. Her research focuses on energy metabolism, gut microbiome interactions, and their evolutionary implications. She leads the Nutritional & Microbial Ecology Lab, exploring how diet, genetics, and microbial communities influence human energy dynamics. Her work integrates evolutionary biology, physiology, and metagenomics to address questions about human uniqueness in digestion, maternal-offspring energy conflicts, and non-caloric dietary components. Office: Museum of Comparative Zoology 542; Email: carmody@fas.harvard.edu. Key research themes include gut microbiome-modulated obesity, placental hormone roles in pregnancy metabolism, and dietary digestibility frameworks. She also investigates evolutionary shifts in gut microbiota during human industrialization and animal domestication. Her lab employs mouse models, comparative studies, and multiomics approaches to dissect host-microbial interactions. Recent articles highlight microbiome effects on exercise-induced weight changes, antibiotic-induced obesity mechanisms, and cross-cultural dietary comparisons. While no awards are explicitly listed, her prolific publications reflect sustained impact in nutritional and evolutionary microbiology. No student advisees or grants are detailed in the provided text.

Lin Heمشاهده پروفایل

استاد

• Non-coding RNA Research
• Cancer Biology
• Stem Cell Biology
• +۳ مورد دیگر

Lin He is the Thomas and Stacey Siebel Distinguished Chair in Stem Cell Research and Professor of Cell Biology and Physiology at the University of California, Berkeley. His laboratory focuses on understanding the biological functions of non-coding RNAs in development and disease, with particular emphasis on microRNAs (miRNAs) in cancer, stem cell biology, and developmental processes. He developed the CRISPR-EZ method for highly efficient mouse genome editing, significantly advancing genetic research. Research interests include miRNAs' roles in tumor progression, metastasis, and pluripotency regulation in stem cells. His work bridges mouse genetics, genomics, and molecular biology to uncover mechanisms governing non-coding RNA functions. Current projects address miRNAs in oncogenesis, stem cell fate determination, and the interplay between non-coding RNAs and retrotransposons in development. Key contributions include identifying miRNA networks in cancer pathways, demonstrating miRNA requirements for ciliogenesis and lung development, and advancing CRISPR-based genome editing techniques. His interdisciplinary approach integrates genetic, genomic, and cellular tools to explore fundamental questions in biology and medicine. Lab website: helabucb.org CRISPR-EZ technology enables 100% genome editing efficiency in mouse zygotes Pioneering studies on miRNA regulation of PTEN, p53, and oncogene pathways

Preet Singhمشاهده پروفایل

استاد

• Corrosion Science
• Electrochemistry
• Metals and Alloys
• +۵ مورد دیگر

Preet Singh is a Professor and Associate Chair for Graduate Studies in the School of Materials Science and Engineering at Georgia Tech, with affiliations to the College of Engineering. His research focuses on corrosion science, electrochemistry, and environmental degradation of materials, particularly metals and alloys. Prior to joining Georgia Tech in 2003, he was a faculty member at the Institute of Paper Science and Technology (IPST), where he investigated corrosion issues in the pulp and paper industry. Professor Singh's work explores fundamental mechanisms of material degradation in industrial environments, aiming to develop mitigation strategies against environment-induced failures. Key research areas include corrosion fatigue, hydrogen embrittlement, stress corrosion cracking, and oxidation behavior. His group employs experimental approaches to study material reliability under varying chemical and mechanical conditions. Recent publications demonstrate interdisciplinary collaboration across oncology, agriculture, and energy systems, reflecting broad applications of materials science principles. Research trends show increased focus on biomedical materials and sustainable technologies alongside core corrosion studies. Professor Singh advises graduate students including Abdullah Alzubail, Yousif Al Rabie, Sai Shreeya, Yara, and Sean Li. He directs the Corrosion and Materials Reliability Laboratory (CMCRL), which partners with industry to solve practical engineering challenges related to material performance.

Konstantinos Kalogeropoulosمشاهده پروفایل

استادیار

• Proteomics
• Snake Venom Research
• Protein Structure Prediction
• +۳ مورد دیگر

Konstantinos Kalogeropoulos is an Assistant Professor at the Department of Biotechnology and Biomedicine, Technical University of Denmark (DTU), leading research at the Cell Diversity Lab. His work bridges proteomics, computational biology, and snake venom research. Current projects: "The Proteomic Landscape during Influenza Infection" (2022-2025) Supervisor for PhD projects on protease network rewiring in psoriasis and wound exudate degradomics Research interests include: Proteomic analysis of inflammatory diseases Snake venom toxin structure prediction Extracellular matrix biomechanics De novo peptide sequencing algorithms Computational modeling of protease networks Recent article trends demonstrate his work in • Database-free proteomics (InstaNovo/InstaNexus) • Snake venom pathophysiology (V-ToCs clustering) • Inflammatory disease biomarkers (psoriasis, impaired healing) • Extracellular matrix mechanics (fibronectin tension, gut inflammation) Advising: Supervises PhD students Polhaus, C. J. M. and Haack, A. M., focusing on protease networks and wound healing.

Maria J. Redondoمشاهده پروفایل

استاد

• Type 1 Diabetes
• Genetics of Autoimmune Diseases
• Diabetes Heterogeneity
• +۳ مورد دیگر

Maria J. Redondo is a Professor at Baylor College of Medicine and leads the Maria J. Redondo Lab at Texas Children’s Hospital, focusing on Type 1 Diabetes across four core areas: Genetics for prediction models and trial candidate selection Heterogeneity in diabetes pathogenesis Prevention through clinical trials Atypical Diabetes and Racial/Ethnic Influences Research Trends: Her recent articles emphasize genetic risk modeling, BMI correlations in pediatric diabetes, and HLA studies. The work integrates autoimmunity , metabolic research , and epidemiological analysis . Scientific Awards: Elected to the Society for Pediatric Research (2014) JDRF Early Career Development Award (2002) JDRF Postdoctoral Fellowship (2000) Immunology of Diabetes Society Junior Investigator Award (1998) Mentoring: Dr. Redondo mentors fellows and students in projects like COVID-19 and Diabetes and Racial Differences in Insulin Pump Uptake , with grants from NIH , Medtronic , and Hemsley Charitable Trust .

Jeff Schoreyمشاهده پروفایل

استاد

• Microbiology
• Immunology
• Infectious Diseases
• +۹ مورد دیگر

Jeff Schorey is the George B. Craig Jr. Professor and a full Professor in the Department of Biological Sciences at the University of Notre Dame, where he has been a faculty member since 2004. He currently serves as Director of the Integrated Biomedical Sciences (IBMS) graduate program and previously held leadership roles including Chair of the Institutional Animal Care and Use Committee (IACUC) and Associate Director of the Eck Institute for Global Health. His research focuses on the pathobiology of mycobacterial diseases, particularly Mycobacterium tuberculosis and M. avium . His work investigates the molecular interactions between mycobacteria and host macrophages, with a special emphasis on the role of exosomes in immune modulation, diagnostics, and vaccine development. He also explores novel antibiotic development in collaboration with chemists at Notre Dame and global partners. His recent publications reveal a strong trend in extracellular vesicle biology, host-pathogen signaling, and translational applications in TB diagnostics and treatment. The articles span immunology, microbiology, and molecular biology, with recurring themes in exosome function, RNA sensing, and antimicrobial development. George B. Craig Jr. Collegiate Professor Dr. Schorey has advised graduate students and leads an active research lab focused on mycobacterial pathogenesis. His work is supported by collaborations across disciplines and institutions, particularly in drug development and clinical translation. He has contributed significantly to understanding how exosomes can serve as both biomarkers and therapeutic tools. His lab employs cellular immunology, animal models, and clinical sample analysis to study mycobacterial infections. He leads the IBMS program, shaping graduate education in biomedical sciences at Notre Dame.

• Microbiome Studies
• Computational Genomics
• Host-Microbiome Interactions
• +۳ مورد دیگر

Jethro Johnson is an Innovation Track Principal Investigator at the Kennedy Institute of Rheumatology and Deputy Director of the Oxford Centre for Microbiome Studies (OCMS) at the University of Oxford. His work integrates computational genomics and microbiome research to explore host-microbiome interactions in health and disease. PhD in Nutritional Ecology (University of Auckland, 2012) MRC Career Development Fellowship Former postdoctoral researcher at Jackson Laboratory for Genomic Medicine Research focuses on: Mechanistic understanding of gut microbiome impacts on metabolic diseases Multi-omic data integration for host-microbiome studies Computational approaches to microbiome analysis Methodological developments in 16S rRNA gene profiling Publications emphasize microbiome-disease associations, methodological innovations, and computational genomics applications across human and mouse models. Key themes include metabolic dysfunction, immune interactions, and microbial diversity analysis. Scientific recognition includes: MRC Career Development Fellowship in Computational Genomics As OCMS Deputy Director, he contributes to advancing microbiome research infrastructure and collaborative projects while leading his own computational genomics group at the Kennedy Institute.

Daniel Razanskyمشاهده پروفایل

استاد

• Biomedical Imaging
• Functional Imaging
• Molecular Imaging
• +۷ مورد دیگر

Daniel Razansky is a Full Professor at the Department of Information Technology and Electrical Engineering, ETH Zurich, leading the Professorship for Biomedical Imaging. His research spans engineering, physics, biology, and medicine, focusing on developing advanced in vivo imaging tools like optoacoustic tomography and ultrasound neuromodulation. His recent work emphasizes multi-scale functional and molecular imaging , with applications in neuroscience , Alzheimer’s disease , and stroke diagnostics . Collaborations include National Tsing Hua University and the EU Horizon consortium SWEEPICS. Current projects target hybrid imaging systems (e.g., MRI-MSOT) and image-guided neuromodulation. Scientific awards include the IPPA James Smith Prize for his contributions. His lab has secured significant grants, including a $2.5M NIH award and SNSF funding. He mentors PhD students like Quanyu Zhou and Eva Remlova, who have received accolades for their research. The Razansky Lab at ETH Zurich’s Preclinical Imaging Center explores medical microrobotics , dynamic fluid flow imaging , and neuroimaging techniques , aiming to bridge engineering with clinical applications.

Asma Zaidiمشاهده پروفایل

استاد

• Parkinson's Disease
• Calcium Signaling
• Dopaminergic Neurons
• +۴ مورد دیگر

Dr. Asma Zaidi is a Professor of Biochemistry at Kansas City University specializing in Parkinson's disease research. Her work investigates the role of plasma membrane Ca2+-ATPase (PMCA) in dopaminergic neuron degeneration. Using human postmortem tissue, cell cultures, and mouse models, her research demonstrates how aging and neurotoxins reduce PMCA function in the substantia nigra, leading to selective neuronal death in Parkinson's. Her findings identify potential therapeutic targets for neuroprotection.

Peter A. Jonesمشاهده پروفایل

استاد

• Epigenetics
• DNA methylation
• Cancer epigenetics
• +۷ مورد دیگر

Peter A. Jones is President and Chief Scientific Officer at the Van Andel Institute (VAI) in Grand Rapids, Michigan, where he leads the Department of Epigenetics. He previously served as Director of the USC Norris Comprehensive Cancer Center from 1993 to 2011 and has been a central figure in advancing epigenetics research, particularly in cancer. His laboratory investigates DNA methylation, chromatin dynamics, and epigenetic therapies. Research Interests: Dr. Jones's work centers on epigenetic mechanisms in cancer, including DNA methylation, histone modifications, nucleosome positioning, and the therapeutic potential of epigenetic drugs. His research has pioneered the use of DNA methylation inhibitors like 5-azacytidine and explored viral mimicry as a mechanism for immune activation in cancer. He also studies transposable elements and their role in gene regulation and immune response. Publication Trends: His recent publications (2021–2024) reveal a strong focus on the interplay between epigenetics and immunotherapy, particularly how DNA methyltransferase inhibitors (DNMTi) induce viral mimicry, enhance immune recognition, and improve responses to checkpoint blockade. Studies span hematological malignancies, solid tumors, and T cell biology, with frequent collaboration with Stephen Baylin and others. Scientific Awards: Member, National Academy of Sciences Member, National Academy of Medicine Fellow, AACR Academy Fellow, AAAS Fellow, American Academy of Arts and Sciences Kirk A. Landon Award for Basic Cancer Research (2009) Medal of Honor, American Cancer Society (2011) Outstanding Investigator Grant, NCI Harvey Prize (2024) Advising and Grants: Dr. Jones mentors multiple postdoctoral fellows, graduate students, and research scientists. His lab is supported by major grants, including the VAI-SU2C Epigenetics Dream Team, which has launched 15 clinical trials. He has received sustained funding from the National Cancer Institute and collaborates with institutions worldwide to advance epigenetic therapies. Labs and Teams: He leads the Peter Jones Laboratory at VAI, a multidisciplinary team investigating epigenetic regulation in cancer. The lab includes computational biologists, clinical researchers, and molecular biologists, working on both basic mechanisms and translational applications. The team is part of larger collaborative initiatives such as the VAI-SU2C Epigenetics Dream Team and the International Linked Clinical Trials Program.

Foteini Mourkiotiمشاهده پروفایل

دانشیار

• Muscle Stem Cell Biology
• Mechanobiology
• Aging
• +۷ مورد دیگر

Foteini Mourkioti is an Associate Professor at the University of Pennsylvania's Perelman School of Medicine , with a joint appointment in the Graduate Groups of Cell and Molecular Biology and Bioengineering . She co-directs the Musculoskeletal Regeneration Program at the Penn Institute of Regenerative Medicine and leads the McKay Orthopaedic Research Laboratory . Research Interests : Muscle Stem Cell Biology Mechanobiology Muscle Regeneration Telomere Biology in Muscular Diseases Fibrodysplasia Ossificans Progressiva (FOP) Cardiomyopathy and Aging Key Research Contributions : Developed the Pax7EGFP mouse model for real-time muscle stem cell tracking Discovered telomere shortening as a critical factor in Duchenne Muscular Dystrophy Elucidated the role of NF-κB in muscle stem cell dysfunction Identified Piezo1's role in stem cell morphological states Characterized fibro-adipogenic progenitor dynamics in FOP Scientific Awards : NIH/NHLBI R01 grant recipient (2019) NASA grant awardee (2020, 2017) American Heart Association grant (2017) Muscular Dystrophy Association grant (2019) University Research Foundation grant (2018) Publications & Collaborations : Over 25 publications in high-impact journals like Science Advances , Nature Protocols , and Cell Reports . Collaborates with Penn Cardiovascular Institute and Pennsylvania Muscle Institute.

• Neuroimaging
• Functional Neuroimaging
• Biomedical Imaging
• +۳ مورد دیگر

Evelyn Lake is an Associate Professor in the Department of Radiology and Biomedical Imaging at Yale University, with affiliations to the Wu Tsai Institute and Yale Biomedical Imaging Institute. Her research focuses on functional neuroimaging, particularly using rodent models to study brain connectivity, neurovascular coupling, and disorders like Alzheimer’s disease and autism spectrum disorder. PhD in Medical Biophysics, University of Toronto (2016) Postdoctoral Associate, Yale University (2019) BSc (Honors) in Biophysics, University of Guelph (2010) Her work spans multimodal imaging techniques (e.g., simultaneous Ca2+ and fMRI), examining how genetic mutations (e.g., PTEN, KATNAL2) affect cerebrospinal fluid dynamics and neuronal connectivity. She investigates longitudinal changes in Alzheimer’s models and methodological aspects of animal neuroimaging, such as sample size optimization and awake imaging protocols. Recent publications highlight her contributions to understanding autism-related white matter abnormalities, transdiagnostic connectome predictive modeling, and the impact of neurovascular uncoupling in awake mice. Collaborations include Todd Constable, Francesca Mandino, Xilin Shen, and Xenophon Papademetris.