جستجوی استاد راهنمای دانشگاهی

James Briscoeمشاهده پروفایل

استاد

• Developmental Biology
• Molecular Signaling
• Transcriptional Networks
• +۴ مورد دیگر

James Briscoe is a Senior Group Leader at The Francis Crick Institute in London, where he leads a research group focused on developmental biology and morphogen signaling. He previously held positions at the Medical Research Council's National Institute for Medical Research, which later became part of the Francis Crick Institute. Education: BSc in Microbiology and Virology from the University of Warwick, UK PhD from Imperial Cancer Research Fund/King's College London Postdoctoral training at Columbia University with Thomas Jessell Dr. Briscoe's research focuses on the molecular and cellular mechanisms of graded signaling by morphogens and the role of transcriptional networks in cell fate specification. His laboratory employs a range of experimental and computational techniques using model systems including mouse and chick embryos and embryonic stem cells. His work has significant implications for understanding developmental processes and their relationship to disease. His recent publications demonstrate a continued focus on morphogen gradients, neural tube development, and computational approaches to understanding cell fate decisions. His research increasingly integrates single-cell technologies and computational modeling to unravel the complexities of developmental patterning. Scientific Awards and Honors: EMBO Young Investigator (2001) EMBO Gold Medal (2008) Elected to EMBO (2009) Fellow of the Academy of Medical Sciences (2019) Fellow of the Royal Society (2019) As Editor-in-Chief of the journal Development since 2018, Dr. Briscoe plays a significant role in shaping the field of developmental biology. His leadership extends to mentoring researchers and contributing to scientific policy discussions, as evidenced by his recent publication 'Science under siege: protecting scientific progress in turbulent times.' Dr. Briscoe's laboratory at the Crick Institute is well-equipped with access to advanced facilities including light microscopy, flow cytometry, genomics, and computational resources, enabling a multidisciplinary approach to developmental biology questions.

• Stem Cell Biology
• Genetic Engineering
• Epigenetics
• +۵ مورد دیگر

Konstantinos Anastassiadis is a Professor at the Center for Molecular and Cellular Bioengineering (CMCB) of Dresden University of Technology , leading the Stem Cell Engineering group at the Biotechnology Center (BIOTEC) . His research focuses on unraveling molecular pathways regulating stem cell self-renewal and lineage commitment, with a strong emphasis on genetic engineering tool development and epigenetic mechanisms during cellular reprogramming. The lab utilizes mouse and human embryonic stem cells, neural stem cells, mesenchymal stromal cells, and induced pluripotent stem cells (iPSCs) in their investigations. Core Research Areas: Molecular regulation of stem cell fate Epigenetic mechanisms (e.g., UTX/UTY histone demethylases) Genetic engineering tool development (Flp, Dre, Vika recombinases, CRISPR protocols) Conditional immortalization systems for rare cell expansion Publications highlight his contributions to understanding: Role of histone methyltransferases (MLL1, MLL2, Setd1b) in hematopoiesis and cancer Epigenetic regulation during mouse development and spermatogenesis Genetic tools for protein tagging, transposon-mediated BAC transgenesis Interactions between stem cells and niche microenvironments Transcriptional and mechanical markers during reprogramming Collaborations span immunology , developmental biology , and bioinformatics . The lab actively participates in teaching activities at CMCB and maintains a focus on translational applications of stem cell research.

• Applied Mathematics
• Mathematical Physics
• Neurosciences
• +۴ مورد دیگر

Professor Paul C. Bressloff holds the Chair in Applied Mathematics and Stochastic Processes at Imperial College London's Department of Mathematics within the Faculty of Natural Sciences. His research focuses on stochastic and non-equilibrium processes, particularly in molecular and cell biology, utilizing tools from probability theory, statistical physics, and dynamical systems. He authored a seminal textbook Stochastic Processes in Cell Biology (Springer), with a 2nd edition published in 2022. Previously, he led the graduate program in mathematical biology at the University of Utah from 2001 to 2023. Research interests include stochastic multi-particle systems, active particles, phase separation, and diffusion across semi-permeable interfaces. His work spans applications in neural field theory, cytoneme-mediated morphogenesis, and protein trafficking. He is affiliated with the Biomathematics Group and Mathematical Physics Group at Imperial. Recent articles explore stochastic resetting in search processes, narrow-capture problems, and hybrid models of switching diffusions. His advising includes over 20 graduate students, many now faculty in mathematical biology. His contributions bridge applied mathematics and biological systems, emphasizing interdisciplinary approaches to complex stochastic phenomena.

Kunihiko Kanekoمشاهده پروفایل

استاد

• Theoretical Biophysics
• Complex Systems
• Chaos
• +۶ مورد دیگر

Kunihiko Kaneko is a Professor at the Niels Bohr Institute, University of Copenhagen, with a distinguished career in theoretical biophysics and complex systems. He received his PhD and MSc in Physics from the University of Tokyo, and has held leadership roles at the Universal Biology Institute and Center for Complex Systems Biology. PhD Physics, 1984 - University of Tokyo MSc Physics, 1981 - University of Tokyo His research spans five primary areas: Universal Biology, Evolutionary Constraints, Ecosystem Dynamics, Neural Cognition, and Universal Anthropology. He has published extensively on multi-level consistency principles, dimensional reduction in biological systems, and reciprocity between robustness and plasticity across scales. Recent publications show strong focus on microbial ecosystems (2025), evolutionary game theory (2025), neural modular architectures (2024), and dimensional reduction in cellular systems (2024). His work bridges physics and biology through dynamical systems theory applied to diverse phenomena from protocells to human societies.

Petra Schwilleمشاهده پروفایل

استاد

• Molecular Biophysics
• Cellular Biophysics
• Synthetic Biology
• +۵ مورد دیگر

Prof. Dr. Petra Schwille is a Director at the Max Planck Institute of Biochemistry and former C4 Professor of Biophysics at Dresden University of Technology . Her work spans molecular and cellular biophysics, synthetic biology, and single-molecule techniques. Academic disciplines: Natural sciences, biological sciences, physical sciences Key roles: Editorial Board member (Nature Methods, Biophysical Journal), Governing Council of Biophysical Society Research Focus includes membrane biophysics, protein interactions, and microfluidic systems. Her publications emphasize Fluorescence Correlation Spectroscopy (FCS) , receptor-ligand dynamics, and self-organization in bacterial cell division. Developed in vitro models for spatial regulation in cells Explored calmodulin availability and morphogen gradient formation Scientific Recognition includes prestigious awards like the Gottfried Wilhelm Leibniz Prize (2010) and the Biofuture grant (1998) . Max Planck Fellow (2005) Young Investigator Award (2003) Leadership & Service involves roles such as Dean of Studies for Nanobiophysics at TU Dresden and Vice Dean of the Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB) . She also contributes to editorial and advisory boards in biophysics and science policy.

• Organoid Engineering
• Systems Biology
• Developmental Biology
• +۳ مورد دیگر

Keisuke Ishihara is an Assistant Professor in the Department of Computational and Systems Biology at the University of Pittsburgh School of Medicine. His research focuses on engineering human brain and cardiac organoids using genetic, chemical, and computational approaches to uncover novel regulatory mechanisms and physical principles underlying tissue development. His lab is located at Biomedical Science Tower 3, with an office in room 10020A. Dr. Ishihara holds a PhD in Systems Biology from Harvard University. His work bridges synthetic biology, developmental biology, and biophysics to address fundamental questions in organogenesis and cellular morphogenesis. Recent research highlights include studies on BMP-mediated neural tube patterning in organoids and the biophysical dynamics of microtubule assemblies in large cells. Publications from his lab emphasize interdisciplinary approaches to understand cell size scaling, mitotic spindle dynamics, and self-organization in synthetic tissues. His team has contributed to advancements in organoid technology, uncovering dormant genetic programs and physical principles governing tissue architecture. Laboratory activities are centered at the University of Pittsburgh, collaborating with the School of Medicine's computational and systems biology initiatives. For more details, visit his lab website linked below.

Michael Boutrosمشاهده پروفایل

استاد

• Functional Genomics
• Structural Genomics
• Wnt Signaling
• +۷ مورد دیگر

Michael Boutros is a Full Professor at Heidelberg University and Head of Division at the German Cancer Research Center (DKFZ). He currently serves as Dean of the Medical Faculty at Heidelberg University (since 2023) and Director of the Marsilius Kolleg (since 2020). He has held leadership roles including Coordinator of the Functional and Structural Genomics Program at DKFZ (2014–2023) and Acting Scientific Director (2015–2016). His academic base is within the Medical Faculty, focusing on molecular oncology and functional genomics. PhD, Witten/Herdecke University (1993–1996) Postdoctoral Research, Harvard Medical School (1999–2003) MPA, John F. Kennedy School of Government, Harvard University (1999–2001) Additional training: Cold Spring Harbor Laboratory, SUNY Stony Brook His research centers on Wnt signaling, functional genomics, and cancer pathways. He leads major research initiatives such as CRC 1324 on Wnt signaling and the ERC Synergy Grant DECODE. His work integrates high-throughput screening, CRISPR, and systems biology to dissect signaling networks in cancer and development. He has pioneered genome-wide RNAi and CRISPR screens to identify novel regulators of Wnt signaling across models. The 15 most recent articles reflect a strong focus on Wnt pathway regulation using functional genomics in both Drosophila and mammalian systems. Themes include high-throughput screening, CRISPR-based validation, cross-species conservation, and therapeutic targeting. Keywords span Cancer Biology, Systems Biology, and Signal Transduction, with subfields like RNAi, ubiquitination, stem cell regulation, and machine learning in image analysis. Michael Boutros has received numerous scientific honors: Elected member, Leopoldina National Academy of Sciences (2022) Elected member, Heidelberg Academy of Sciences (2022) EMBO Member (2013) ERC Advanced Grant (2012) Johann-Georg Zimmermann Research Award (2007) EMBO Young Investigator (2005) Member, 'Die Junge Akademie' (2003) He has been a recipient of the Emmy-Noether Program, McCloy Fellowship, Boehringer Ingelheim PhD Fellowship, Studienstiftung Fellowship, and Fulbright Fellowship. As a mentor and research leader, he has supervised numerous early-career scientists and coordinated large collaborative grants including the FP7 'CancerPathways' project. He currently serves as Speaker of the Research and Strategy Commission at Heidelberg University and Managing Director of the Health and Life Science Alliance Heidelberg Mannheim. He leads the CRC 1324 on Wnt signaling and is Coordinating PI of the ERC Synergy Grant DECODE. He is also Spokesperson of DFG Research Group 1036 and Coordinator of the former FP7 Coordinated Project 'CancerPathways'. His lab employs cutting-edge functional genomics tools to decode signaling networks in cancer and development.

• Applied Mathematics
• Mathematical Biology
• Multiscale Modelling
• +۵ مورد دیگر

Prof. Radek Erban is a Professor of Applied Mathematics at the Mathematical Institute , University of Oxford. He is affiliated with the Oxford Centre for Industrial and Applied Mathematics and works across interdisciplinary fields including Mathematical Biology, Stochastic Processes, and Reaction-Diffusion Systems. His research focuses on: Multiscale modeling of biological and chemical processes Stochastic simulation algorithms for reaction-diffusion systems Mathematical analysis of collective behavior in biological systems Computational methods for chemotaxis and gene regulatory networks Partial differential equation models for biological phenomena Recent work explores multi-resolution simulations of ions, morphogen gradient modeling, and hybrid numerical methods for stochastic processes. His publications span journals in applied mathematics, computational biology, and physical sciences. Current projects involve bridging atomistic and continuum models for chemical systems.

Jianping Fuمشاهده پروفایل

استاد

• Stem Cell Bioengineering
• Developmental Bioengineering
• Mechanobiology
• +۴ مورد دیگر

Jianping Fu is a Professor in the Department of Mechanical Engineering at the University of Michigan , with joint appointments in Biomedical Engineering and Cell and Developmental Biology. His research integrates micro/nanoengineering , mechanobiology , and stem cell biology to model human development and disease. Education: PhD (MIT, 2007), BE (University of Science and Technology of China, 2000) His research interests focus on stem cell bioengineering , developmental bioengineering , and mechanobiology , particularly in modeling early post-implantation human development, neural tube formation, and pluripotent stem cell mechanoregulation. His work combines biomimetic culture systems with microfluidic gradients to study embryogenesis and organogenesis. Recent publications highlight advances in human embryo modeling (2024 Cell, Nature, Cell Stem Cell), neural tube patterning (2024 Nature), and mechanobiology of stem cells (2024 Nature Reviews Physics). These studies emphasize computational methods , single-cell analysis , and standardization of embryo models . Scientific honors include: Friedrich Wilhelm Bessel Research Award (2022) ISSCR Merit Award (2024) Fellow, American Institute for Medical and Biological Engineering (2019) NSF CAREER Award (2012) Life Member, World Association of Chinese Biomedical Engineers (2024) Dr. Fu mentors extensively, with 20+ alumni including PhD students and postdocs now in academic and industry positions. His lab has received $3M NIH funding for immunological diagnostics and MTRAC grants for translational research. Collaborations with institutions like Cincinnati Children's Hospital and Rice University enhance his interdisciplinary approach to regenerative medicine.

Laura Burrusمشاهده پروفایل

استاد

• Developmental biology
• Cancer biology
• Climate change
• +۴ مورد دیگر

Laura (Kai) Burrus is a Professor in the Department of Biology within the College of Science and Engineering at San Francisco State University, where she has been a faculty member since 1997. Her research has evolved from studying Wnt signaling in developmental biology to addressing climate change resilience through microbial ecology. Education: BS in Chemistry - College of William and Mary (1986) PhD in Biochemistry - University of Wisconsin-Madison (1991) Post-doc in Developmental Biology - Harvard University (1996) Dr. Burrus' research has historically focused on the biochemical and cellular mechanisms underlying Wnt gradient formation in chick embryos, with relevance to birth defects and cancer. Her work has been funded by NIH, NSF, CSUPERB, and MDA over the last 20 years. She is currently transitioning her research to analyze the role of microbes in climate change resilience, motivated by her recognition that 'climate change is inherently racist.' She is actively involved with Lifting Black Voices in STEM and is leading an effort to launch an interdisciplinary Certificate in Climate Change Causes, Impacts, and Solutions. As one of five LGBTQIA biology faculty at SFSU, she brings unique perspectives to her work on inclusive classroom practices. Her publication record spans from 1994 to 2021, with recent work focusing on Wnt signaling mechanisms, educational approaches in STEM, and the transition to climate change research. Her research shows a clear evolution from fundamental developmental biology to applied environmental science, while maintaining a strong foundation in molecular and cellular mechanisms. Scientific Contributions: Pioneering work on Wnt protein trafficking and modification Research connecting Wnt signaling to cancer biology Leadership in developing inclusive STEM education practices Transition to climate change resilience research with focus on microbial ecology Dr. Burrus has mentored numerous undergraduate and graduate students throughout her career, with many alumni going on to pursue advanced degrees and careers in science. She has been actively involved in pedagogical innovation and is pioneering new approaches to effectively communicate research to both scientific and lay communities. Her lab has received funding from multiple sources including NIH, NSF, CSUPERB, and MDA. She is currently involved in oyster reef restoration research in the San Francisco Bay, investigating microbial communities as indicators of climate resilience. This work represents an aspirational shift from her previous focus, leveraging molecular expertise to address pressing climate challenges while mentoring students from diverse backgrounds.

Holger Knautمشاهده پروفایل

دانشیار

• Collective Cell Migration
• Actin Polymerization
• RhoA Signaling
• +۴ مورد دیگر

Holger Knaut is an Associate Professor in the Department of Cell Biology at NYU Grossman School of Medicine . His research focuses on understanding the molecular and mechanical mechanisms underlying collective cell migration, tissue morphogenesis, and cytoskeletal dynamics using zebrafish models and quantitative imaging techniques. Key research areas: Collective cell migration, RhoA signaling, focal adhesions, actin polymerization Methodologies: Genetics, live-cell imaging, biomechanical analysis Notable findings: Discovery of rear traction forces in tissue migration, integration of adhesion codes in pattern formation His publications in top journals like Nature Cell Biology and Science demonstrate his expertise in developmental biophysics and cell signaling regulation. Contact: Holger.Knaut@nyulangone.org

Peter Matthiasمشاهده پروفایل

استاد

• Biochemistry
• Cell Biology
• Cell division
• +۷ مورد دیگر

Matthias Peter is a Professor of Biochemistry at ETH Zurich, leading research into mechanisms governing cell growth and division. His laboratory focuses on ubiquitin-dependent regulation of DNA replication and mitosis, and autophagy's role in cellular quality control. He chairs the Department of Biology (2011-2015) and holds leadership roles in Switzerland's research infrastructure, including Vice Chair of ScopeM's microscopy platform. His academic career includes roles at ISREC (1996-2002) and postdoctoral training at UCSF (1991-1996). Education: PhD in Biochemistry from ISREC (1991), ETH Zurich diploma in Gene Technology (1987). Research interests span molecular mechanisms of cell division, ubiquitin systems, and autophagy. Awards include ERC Advanced Grant (2011) and UBS Excellence in Research (2002). Leadership: Member of Swiss National Research Council, SNF selection committee, and SWTR council. Over 20 years of committee service in national research programs. His lab's work is published in top journals like Science, Nature, and Molecular Cell.

• Biophysics
• Theoretical Physics
• Developmental Biology
• +۲ مورد دیگر

Edouard Hannezo is a Professor at the Institute of Science and Technology Austria (ISTA) since 2022, focusing on the application of theoretical physics to elucidate design principles of self-organization in biological systems. His research spans multiple scales, from cytoskeletal dynamics to tissue architecture, with key collaborations in developmental and cell biology. The Hannezo Group integrates solid/fluid mechanics, statistical physics, and soft materials engineering to address fundamental questions in morphogenesis. Current Research: Investigates stochastic branching in mammalian organs, active fluids in cytoskeletal organization, and fate selection during development. Key Contributions: Developed biophysical frameworks for intestinal organoid morphogenesis, branching morphogenesis, and mechanochemical feedback loops. Scientific Awards: EMBO Young Investigator Award (2019) ERC Starting Grant (2019) Wellcome Trust Fellowship (2015) Bettencourt-Schuller Young Researcher Prize (2014) Team: Leads a multidisciplinary team including PhD students (Zuzana Dunajova, Andreas Ehrmann, Kasumi Kishi) and postdocs (Oliver Drozdowski, Yuting Li), with technical support from image analyst Suyash Naik.

Albert Erivesمشاهده پروفایل

دانشیار

• Regulatory Genomics
• Evolutionary Genomics
• Evolution of Metazoa
• +۶ مورد دیگر

Albert Erives is an Associate Professor in the Department of Biology at the University of Iowa , specializing in regulatory genomics, evolutionary genomics, and the evolution of metazoans. His research focuses on decoding gene regulatory logic in DNA sequences, particularly during animal embryogenesis, using comparative genomics to identify regulatory modules driving phylogenetic transitions. PhD from University of California, Berkeley His work spans eukaryotic gene regulation, integrating biochemistry, molecular genetics, and computational biology to uncover principles of organismal evolution. Recent studies include viral nucleosome structure, Notch signaling pathway evolution, and enhancer organization in model organisms like Drosophila and Ciona . Notable scientific awards include the NSF CAREER Award (2012, 2010) . He actively seeks graduate students and postdoctoral researchers for his laboratory, which utilizes core facilities such as the Carver Center for Genomics.

Berta Verdمشاهده پروفایل

پژوهشگر ارشد

• Evolution of Development
• Dynamical Systems Theory in Biology
• Embryonic Axial Elongation and Segmentation
• +۳ مورد دیگر

Berta Verd is the Peter Brunet Fellow in Biological Sciences at Jesus College, University of Oxford. She holds a BSc in Mathematics from the Polytechnic University of Catalonia, followed by an MSc in Medicine, Science and Society from King’s College London, an MRes in Systems and Synthetic Biology from Imperial College London, and a PhD in Biomedicine from Pompeu Fabra University. Her research focuses on evolutionary developmental biology, applying dynamical systems theory to biological problems such as embryonic axial elongation, segmentation, and cichlid fish evolution. She teaches Biology courses at Jesus College and actively contributes to interdisciplinary research in developmental dynamics. Her work explores the modularity of segmentation clocks, the role of cell movements in pattern formation, and evolutionary processes in African cichlids. Recent studies include analyses of skeletal diversity in Lake Malawi cichlids using micro-CT imaging and computational modeling of gene regulatory networks. She also investigates critical transitions in developmental systems and the interplay between morphogen gradients and positional information. Advising and grants: No student advisees or grant details are explicitly listed in the provided texts. Her research is supported through her fellowship and institutional affiliations. She is associated with labs focused on systems biology and evolutionary developmental biology at the University of Oxford and collaborating institutions. Labs/Teams: While specific lab names are not mentioned, her research aligns with interdisciplinary teams studying developmental dynamics, evolutionary biology, and systems approaches in the Biological Sciences department at Oxford.