جست‌وجوی استاد و پژوهشگر

Weiqiang Chenمشاهده پروفایل

استاد

• Lab-on-a-Chip
• Organ-on-Chip
• Biomaterials
• +۷ مورد دیگر

Weiqiang Chen is a Professor of Mechanical and Biomedical Engineering at New York University's Tandon School of Engineering and Director of Research and PhD Programs. He holds a joint appointment at NYU Langone's Perlmutter Cancer Center as a Faculty Member of the Tumor Immunology Research Program. B.S. in Physics (Nanjing University, 2005) M.S. in Electrical Engineering (Shanghai Jiao Tong University, 2008) M.S. in Electrical and Computer Engineering (Purdue University, 2009) Ph.D. in Mechanical Engineering (University of Michigan, 2014) His research focuses on Lab-on-a-Chip , Organ-on-Chip systems, Biomaterials , and Mechanobiology , with applications in cancer biology, stem cell engineering, and immune monitoring. He pioneers microfabrication technologies for real-time observation of cellular interactions, including CAR T-cell immunotherapy efficacy and tumor microenvironment dynamics. Recent grants include NSF funding for leukemia bone marrow niche modeling, NIH Trailblazer Awards for glioblastoma immunotherapy research, and collaborations with the Arthritis Foundation for synovium-on-chip rheumatoid arthritis studies. His work has been supported by over $2M in federal and institutional research funding. National Science Foundation (NSF) grants for leukemia-on-chip and glioblastoma modeling National Institutes of Health (NIH) awards for immunotherapy research American Heart Association fellowships and institutional training programs Chen's scientific awards include the American Heart Association Fellow distinction, multiple Young Investigator Awards from Lab on a Chip and Biomedical Engineering Society, and recognition for his dissertation on nanotopography in stem cell differentiation. He leads the Applied Micro-Bioengineering Laboratory (AMBL) , which develops microphysiological systems for drug testing and personalized medicine. His team has created the first immunocompetent leukemia-on-a-chip for CAR T-cell therapy screening and glioblastoma models that enable patient-specific immunotherapy validation.

Christopher M. Overallمشاهده پروفایل

استاد

• Protease Proteomics
• Systems Biology
• Degradomics
• +۶ مورد دیگر

Christopher M. Overall is a Full Professor at the University of British Columbia in the Faculty of Dentistry, Department of Oral Biological and Medical Sciences . He is also a Principal Scientist at the Centre for Blood Research and holds associate memberships in UBC's Biochemistry & Molecular Biology , Obstetrics and Gynecology , and Bioinformatics Graduate Program departments. As a Canada Research Chair Laureate , he pioneered the field of degradomics to study proteases in vivo. B.D.S., University of Adelaide Ph.D., University of Toronto Postdoctoral Fellowship, UBC (with Nobel Laureate Michael Smith) Dr. Overall’s research focuses on protease proteomics and systems biology , particularly degradomics to analyze protease substrates in diseases like COVID-19 and immunodeficiency . His work on matrix metalloproteinases has revealed new therapeutic strategies for inflammatory diseases and cancer . His 15 most recent articles (2015–2008) demonstrate expertise in TAILS proteomics , protein terminomics , and protease network analysis with applications in arthritis , antiviral immunity , and precision medicine . Scientific Awards 2022 Helmut Holzer Award 2018 Royal Society of Canada Fellow 2014 Tony Pawson Canadian Proteomics Award 2013 IADR Distinguished Scientist Award Dr. Overall has mentored 61 trainees , including 9 full professors with department chairs, and received the UBC John McNeill Mentorship Award (2023). He leads the HUPO Chromosome-centric Human Proteome Project and consults for Genentech and Novartis .

Knut Drescherمشاهده پروفایل

دانشیار

• Bacterial Biofilms
• Microbial Multicellularity
• Biophysics
• +۵ مورد دیگر

Prof. Knut Drescher is an Associate Professor at the Biozentrum, University of Basel , leading a research group focused on bacterial biofilms , swarming , and microbial multicellularity . Previously, he served as a Professor of Biophysics and Max Planck Research Group Leader at Philipps-Universität Marburg (2015-2021) and conducted postdoctoral research at Princeton University. Research Interests: Physical and biological mechanisms of biofilm formation Cell-cell interactions in microbial communities Antibiotic resistance in biofilms Hydrodynamics of bacterial swarms Evolution of cooperation in multispecies biofilms Development of bioimaging software (BiofilmQ, BacStalk) Scientific Awards: 2023: SNSF Consolidator Grant 2019: Heinz Maier-Leibnitz Prize (DFG), VAAM Research Prize, IUPAP Young Scientist Prize 2016: ERC Starting Grant Advising & Grants: Advises PhD and Master's students in microbiology, biophysics, and bioinformatics Secured major grants from ERC , HFSP , and DFG

Johannes Larschمشاهده پروفایل

استادیار

• Neuroscience
• Social Behavior
• Neuronal Circuits
• +۳ مورد دیگر

Johannes Larsch is a tenure-track Assistant Professor at the Center for Integrative Genomics within the Faculty of Biology and Medicine at Université de Lausanne (UNIL). His research focuses on understanding the neuronal mechanisms underlying social interactions, using larval zebrafish as a model organism. He employs advanced techniques like virtual reality and optical imaging to study how social signals are processed in the brain. Education: Bachelor of Biology, University of Konstanz, Germany PhD in Neurobiology, Rockefeller University, USA (lab of Cori Bargmann) Postdoc at Max Planck Institute of Neurobiology, Germany (with Herwig Baier) Research interests center on neuronal circuits driving group behavior, social recognition, and the interplay between genetics and environment in shaping behavior. His lab investigates how individual brains coordinate collective social behaviors through studies of neuronal activity and circuit dynamics. Current lab openings include fully funded PhD and PostDoc positions focused on social neuroscience and neurogenomics. Contact: johannes.larsch@unil.ch .

Patricia Championمشاهده پروفایل

استاد

• Molecular Genetics
• Mycobacterial Pathogenesis
• Bacterial Genetics
• +۷ مورد دیگر

Patricia Champion is a Professor in the Department of Biological Sciences at the University of Notre Dame, where she holds the title of Notre Dame Collegiate Professor. Her research is centered on the molecular mechanisms of mycobacterial pathogenesis, with a focus on protein transport and virulence. She is affiliated with the Eck Institute for Global Health and the Center for Rare and Neglected Diseases. PhD in Molecular Biology, Princeton University (2003) B.S. in Biological Sciences, Carnegie Mellon University (1998) Her research interests lie in understanding how pathogenic mycobacteria, including Mycobacterium tuberculosis and M. marinum , cause disease through targeted protein secretion, particularly via the Type VII (ESX-1) secretion system. She investigates how secreted proteins function as effectors and regulate gene expression, and how post-translational modifications like acetylation influence virulence. Her lab employs an interdisciplinary approach combining genetics, molecular biology, proteomics, and transcriptomics. The recent publications highlight a strong focus on ESX-1-mediated secretion, identification of novel substrates, regulatory mechanisms (e.g., WhiB6, EspM), and post-translational modifications. The work spans fundamental bacterial physiology to host-pathogen interactions, contributing to the broader goal of identifying targets for anti-virulence therapeutics against tuberculosis. Her scientific recognition includes being named a Notre Dame Collegiate Professor, a distinguished honor reflecting her scholarly excellence. Dr. Champion leads an active research laboratory committed to fostering an inclusive and respectful environment, emphasizing core values such as integrity, teamwork, and excellence. Her lab's work is supported by ongoing research grants, though specific funding sources are not detailed in the text. The Champion Lab operates within the Department of Biological Sciences and collaborates with key institutes at Notre Dame focused on global and neglected diseases.

Vasilis Ntziachristosمشاهده پروفایل

استاد

• Biomedical Imaging
• Optoacoustic Imaging
• Medical Diagnostics
• +۳ مورد دیگر

Prof. Vasilis Ntziachristos is a Professor and Chair of Biological Imaging at the Technical University of Munich (TUM), leading the Institute of Biological and Medical Imaging at the Helmholtz Centre Munich. His research focuses on developing novel optical and optoacoustic imaging techniques for early disease detection, diagnostics, and theranostics. He holds a PhD in Bioengineering from the University of Pennsylvania and previously served as an Assistant Professor at Harvard University and Massachusetts General Hospital. Affiliations: TUM School of Medicine and Health, Helmholtz Munich, Institute of Biological and Medical Imaging. Key Research Themes: Non-invasive imaging methods, molecular imaging, optoacoustic technology, and clinical translation. His work bridges theoretical developments with clinical applications, including advancements in glucose monitoring, cancer imaging, and drug delivery systems. Notable awards include the Leibniz Prize (2013) and the World Molecular Imaging Society Gold Medal (2015). Labs/Teams: Imaging to Sensing I2S, Optoacoustic Mesoscopy, Fluorescence Imaging, and AI in Optoacoustics. Grants/Projects: Involvement in Horizon Europe initiatives and collaborations with TranslaTUM and Helmholtz Munich. Prof. Ntziachristos actively contributes to education via courses like 'Biological Imaging' and 'Introduction to Bioengineering', fostering the next generation of imaging scientists.

• Virology
• Molecular Biology
• Genomics
• +۶ مورد دیگر

James Van Etten is the William Allington Distinguished Professor of Plant Pathology at the University of Nebraska-Lincoln, affiliated with the School of Biological Sciences and Nebraska Center for Virology. His research focuses on chloroviruses—large dsDNA viruses infecting Chlorella-like algae—with emphasis on DNA replication, restriction systems, and membrane transport proteins. Key research themes include: Viral DNA modification systems Host-virus interactions Structural virology Evolution of organellar genomes Recent work analyzed: SMRT sequencing of viral methylation patterns Chlorovirus cryopreservation methods Potassium channel biophysics Host chemical signaling mechanisms Lab webpage: vanettenlab.unl.edu

• Biosensors
• Functional Nucleic Acids
• Sol-Gel Materials
• +۳ مورد دیگر

John D Brennan is a Professor in the Department of Chemistry & Chemical Biology at McMaster University. He is affiliated with the Biointerfaces Institute and focuses on developing innovative biosensing technologies and functional nucleic acid-based assays. His research integrates materials science, biochemistry, and analytical chemistry to create practical diagnostic tools for healthcare applications. Key research areas include the design of DNA aptamers and DNAzymes for detecting biomarkers (e.g., eosinophil peroxidase, SARS-CoV-2 spike proteins), development of paper-based diagnostic platforms, and optimization of sol-gel materials for enzyme entrapment. His work emphasizes high-throughput screening, point-of-care testing, and CRISPR-based biosensing systems. Notable contributions include a rapid sputum-based assay for asthma biomarkers and a universal DNA aptamer for SARS-CoV-2 variants. His lab also explores functional nucleic acid circuits and their integration into scalable diagnostic devices. Brennan’s teaching includes advanced courses in analytical chemistry and biochemical assay development. His work has been featured in journals like *Angewandte Chemie*, *Analytical Chemistry*, and *ChemBioChem*, with a focus on translating fundamental research into practical clinical applications.

Dan A. Dixonمشاهده پروفایل

استاد

• Cancer Biology
• Molecular Oncology
• RNA Biology
• +۳ مورد دیگر

Dan A. Dixon is a Professor and Associate Director of Community Outreach and Engagement at the Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences (UAMS), where his research focuses on post-transcriptional gene regulation mechanisms in cancer pathogenesis. His academic credentials include: Ph.D. from Northwestern University B.A. from Augustana University Dr. Dixon's research centers on RNA-binding proteins (notably HuR and tristetraprolin) and their role in destabilizing oncogenic mRNA networks. His laboratory investigates how dysregulation of these post-transcriptional controllers permits overexpression of tumor-promoting genes involved in proliferation, angiogenesis, and metastasis. Key focus areas include colorectal cancer mechanisms, autophagy regulation via Rab27B, stress granule dynamics in mutant p53 contexts, and extracellular vesicle-mediated tumor microenvironment activation. Analysis of his 2022-2025 publications reveals intensifying work on XPO1 inhibition for colorectal cancer chemoprevention, Rab27B-autophagy axis characterization, and mutant p53 vulnerabilities. His studies consistently employ molecular techniques, mouse models (APC Min/+ ), and translational approaches to identify biomarkers and therapeutic targets. Dr. Dixon maintains active laboratory facilities at WPRCI 947 and 951, directing research that bridges fundamental RNA biology with clinical oncology applications. His leadership in community outreach complements his bench-to-bedside research philosophy.

Sachdev Sidhuمشاهده پروفایل

استاد پژوهشی

• Synthetic Antibodies
• Protein Engineering
• Biotechnology
• +۵ مورد دیگر

Sachdev Sidhu is a Research Professor and Entrepreneur in Residence at the University of Waterloo. His research focuses on synthetic antibodies, protein engineering, and biotechnological applications. He leads efforts in developing novel therapeutic antibodies, engineered protein systems, and molecular tools for biomedical research. His work spans cancer therapy, viral infection countermeasures, and regenerative medicine. Sidhu is also involved in translational research, bridging academic discoveries with commercial applications through entrepreneurial ventures. Key research interests include synthetic antibody libraries, CAR T-cell engineering, ubiquitin-based therapeutics, and phage display technologies. He has contributed to advancements in targeted therapies for glioblastoma, leukemia, and ocular diseases. His team develops innovative methods for protein design, such as engineered ubiquitin variants and modular antibody architectures. Publications highlight breakthroughs in antibody-based treatments, including synNotch CAR T cells for glioblastoma and neutralizing antibodies against SARS-CoV-2. His work integrates structural biology, molecular biology, and computational approaches to address complex biomedical challenges. Sidhu collaborates with industry partners to advance technologies into clinical and commercial settings.

David Graingerمشاهده پروفایل

استاد

• Bacterial Chromosome Biology
• Pathogenicity
• Antibiotic Resistance Mechanisms
• +۳ مورد دیگر

Professor David Grainger is a faculty member at the University of Birmingham's School of Biosciences, specializing in Molecular Microbiology. He leads the Grainger Lab, focusing on bacterial chromosome biology, pathogenicity, and antibiotic resistance. His research integrates high-throughput techniques and single-molecule analysis to study gene regulation and bacterial pathogenesis. Education: PhD (2004), PGCE (2000), BSc (1999) in Biochemistry from the University of Birmingham. Affiliations: Part of the Institute of Microbiology and Infection (IMI), collaborating with experts in genomics, proteomics, and structural biology. Research Interests: Deciphering chromosome biology of pathogenic bacteria, including transcriptional regulation, toxin production control, and antibiotic resistance pathways. Utilizes cutting-edge methods like Hi-C for 3D chromatin analysis and single-molecule microscopy. Recent Articles: Focused on transposon capture mechanisms, bacterial promoter diversity, and quorum sensing signaling. Highlights include studies on Salmonella regulons and Vibrio cholerae biofilm suppression. Awards: Wellcome Trust Career Development Fellowship (2008), Runner-up in 'Science Snaps' competition for scientific communication. Grants: Career Development Fellowship-funded establishment of his research group at the University of Warwick (2008). Labs/Teams: Grainger Lab at the University of Birmingham, part of the IMI network. Engages in public science outreach via Twitter and lab website.

• Nanomedicine
• Therapeutic Targeting
• Drug Delivery Systems
• +۴ مورد دیگر

Dr. Susan Hua is an Associate Professor at the University of Newcastle's School of Biomedical Sciences and Pharmacy, specializing in translational nanopharmaceutics and therapeutic targeting. She established the first translational nanopharmaceutics laboratory in the Hunter region, focusing on drug delivery systems for gastrointestinal, musculoskeletal, and reproductive pathologies. Education: Bachelor of Pharmacy with Honours, University of Queensland (UQ) PhD in Neuroscience and Nanotechnology, UQ Research Interests: Her work centers on using nanotechnology to create targeted drug delivery systems for diseases such as chronic pain, inflammatory conditions, and obstetric complications. Key focuses include oxytocin receptor-targeted liposomes for uterine therapies and localized drug delivery to bypass biological barriers. Awards & Recognition: 2020 DVC(A) Educator Innovation Award 2017 NSW Premier's Early Career Researcher of the Year 2015 HMRI Early Career Researcher of the Year Grants & Collaborations: A/Prof Hua has secured over $5.5M in grants, including NHMRC and ARC funding. She collaborates with institutions like HMRI, John Hunter Hospital, and global teams on projects like nanoparticle-based treatments for preterm labor and uterine hemorrhage. Teaching & Leadership: She coordinates pharmacy programs, emphasizing clinical application and innovation. Her courses include Pharmacotherapeutics and Pharmacy Practice, with awards for teaching excellence (2020, 2011). Labs & Programs: Head of Therapeutic Targeting Program, University of Newcastle Director, Translational Pharmaceutics & Medical Technologies Theme (HMRI)

Zhe Jiمشاهده پروفایل

استادیار

• Data Science
• Computational Biology
• Functional Genomics
• +۴ مورد دیگر

Zhe Ji is an Assistant Professor in the Department of Biomedical Engineering at McCormick School of Engineering and the Department of Pharmacology at Feinberg School of Medicine, Northwestern University. His research integrates computational and experimental genomics to study gene transcription and RNA translation in cell fate commitment and oncogenic processes, aiming to develop precision medicine strategies. **Education**: Postdoctoral Fellow in Cancer Systems Biology, Harvard Medical School Postdoctoral Fellow in Computational Biology, Broad Institute of MIT and Harvard Ph.D. in Computational Genomics, Rutgers University B.S. in Biotechnology, Nanjing University, China **Research Focus**: Keywords include Data Science, Computational Biology, Functional Genomics, RNA, Cancer, Inflammation, and Machine Learning. The lab explores regulatory mechanisms underlying disease, with a focus on translational control, cancer metastasis, and inflammatory networks. **Grants & Advising**: No specific grants or student advisees listed. The lab emphasizes collaborative projects and computational-experimental approaches. **Lab Affiliations**: Zhe Ji’s lab is part of Northwestern’s interdisciplinary environment, bridging engineering and medicine to advance genomic technologies and therapeutic strategies.

Sara Galliniمشاهده پروفایل

استادیار

• Cancer Biology
• Cellular Dynamics
• Epithelial Biology
• +۳ مورد دیگر

Sara Gallini is an Assistant Professor at EPFL, leading the Gallini Lab within the ISREC Department of the School of Engineering (SV). Her research focuses on understanding how healthy and oncogenic cells compete in skin epithelium, aiming to identify therapeutic targets for skin cancer prevention. She holds a Tenure Track position and teaches in the Life Sciences Engineering program. Her lab employs advanced in vivo imaging and single-cell analysis techniques. Education details are not explicitly provided, but her career includes a postdoctoral fellowship with the HFSP. Her research integrates molecular, cellular, and systems-level approaches to study cancer initiation and tissue homeostasis, particularly in injury-driven dynamics. Lab Members: Includes PhD student Mustafa Öztürk and technical staff Mélanie Sipion. Key Research Themes: Oncogenic cell competition, epidermal regeneration, EGFR/ERK signaling, and therapeutic target discovery. Her lab collaborates with clinical teams and uses models like mouse skin to study tumor suppression mechanisms. Future work aims to leverage healthy cell dynamics for cancer treatment strategies. Contact: SV 2527 office, +41216936764, sara.gallini@epfl.ch .

• Machine Learning
• Computational Neuroscience
• Artificial Intelligence
• +۷ مورد دیگر

Aapo Hyvärinen is a Professor of Computer Science at the University of Helsinki , affiliated with the Helsinki Institute for Information Technology and the Helsinki Probabilistic Machine Learning Lab . He previously held the position of Professor of Machine Learning at the Gatsby Computational Neuroscience Unit, University College London (2016-2019). Education : Undergraduate Mathematics at University of Helsinki, Vienna, and Paris; Ph.D. in Information Science from Helsinki University of Technology (1997) His research focuses on machine learning and computational neuroscience , particularly: Independent Component Analysis (ICA) Natural Image Statistics Causal Representation Learning Neural Signal Processing Applications to brain imaging (MEG, CryoEM) Recent publications emphasize causal discovery , identifiable machine learning , and nonlinear ICA . Key projects include: VETURI (AI for health) DIGIMIND (AI in mental health) CIFAR grants (2022-2025) Scientific awards : Highly Cited Researcher (2010) He serves as Action Editor for the Journal of Machine Learning Research and Neural Computation , and has held Area Chair roles at NeurIPS, ICML, ICLR, AISTATS, and UAI conferences. His work bridges theoretical machine learning with neuroscience and philosophical implications of artificial intelligence .