جستجوی استاد راهنمای دانشگاهی

Michelle Farkasمشاهده پروفایل

دانشیار

• Chemical Biology
• Cancer Biology
• Circadian Rhythms
• +۴ مورد دیگر

Michelle Farkas is an Associate Professor in the Department of Chemistry at the University of Massachusetts Amherst. Her work bridges chemical biology, synthetic chemistry, and cancer biology to develop molecular tools for studying circadian rhythms and macrophage phenotypes in oncology contexts. Affiliated with the Graduate Program in Molecular & Cellular Biology Faculty member at the Center for Bioactive Delivery and Models to Medicine within the Institute for Applied Life Sciences Research focuses on: Designing reporters and modulators for circadian rhythms in cancer models Engineering macrophages for anti-cancer polarization and targeted delivery Developing chemically modified cells and nanozymes for therapeutic/diagnostic applications Scientific contributions include chemical modulation of circadian clocks, bioorthogonal nanozyme systems, and novel cell-based delivery platforms. Her recent publications highlight interdisciplinary approaches combining synthetic chemistry with cancer immunology. DOD-BCRP Postdoctoral Fellow Current projects aim to translate molecular tools into clinical diagnostics and therapies, leveraging collaborations across chemistry, biology, and medicine.

Somak Duttaمشاهده پروفایل

دانشیار

• Statistics
• Machine Learning
• Genomics
• +۵ مورد دیگر

Somak Dutta is an Associate Professor at Iowa State University conducting interdisciplinary research at the intersection of statistical methodology, machine learning, and agricultural sciences. His work addresses critical challenges in plant breeding, genomics, and environmental modeling through innovative quantitative approaches. His academic foundation includes: PhD in Statistics, University of Chicago, 2015 M.Stat (First Division with Distinction), Indian Statistical Institute, Kolkata, 2010 B.Stat (Honours with Distinction), Indian Statistical Institute, Kolkata, 2008 Dr. Dutta specializes in developing advanced statistical frameworks for high-dimensional data analysis, Bayesian variable selection, and spatial modeling. His research directly impacts plant breeding programs through applications in phenotyping, haploid induction systems, drought response mechanisms, and genetic architecture studies across key crops including maize, soybean, and mungbean. He also contributes to meteorological science through machine learning applications for severe weather verification. Analysis of his 2023-2025 publications reveals two dominant research streams: (1) agricultural applications focusing on genomic selection, phenotyping technologies, and stress response modeling in crops, and (2) meteorological innovations applying machine learning to severe thunderstorm wind verification and precipitation forecasting. Both streams demonstrate his signature approach of developing novel statistical methodologies tailored to domain-specific challenges. No scientific awards were documented in the provided materials. Information regarding student advising, grant funding, laboratory infrastructure, or collaborative teams was not available in the source documentation.

Timothy D. O'Brienمشاهده پروفایل

استاد

• Veterinary Pathology
• Comparative Pathology
• Transplantation Biology
• +۴ مورد دیگر

Timothy D. O'Brien is a Professor and Division Head of Comparative Pathology in the Department of Veterinary Population Medicine at the University of Minnesota College of Veterinary Medicine. He holds multiple affiliations including the Stem Cell Institute, Masonic Cancer Center, and Institute for Engineering in Medicine. Dr. O'Brien also serves as faculty for the Masters Program in Stem Cell Biology. Dr. O'Brien earned his BS, DVM, and PhD degrees from the University of Minnesota in 1976, 1978, and 1985 respectively. He is a Diplomate of the American College of Veterinary Pathologists (Anatomic Pathology, 1984). His research spans veterinary pathology, transplantation biology, stem cell research, and cancer biology with a focus on comparative pathology models. He has made significant contributions to understanding interspecies organogenesis, islet xenotransplantation, and animal models for human diseases. His work bridges veterinary and human medicine, exploring translational applications of findings from animal models to human conditions. Recent publications highlight innovative approaches to transplantation without long-term immunosuppression and studies on hemangiosarcoma biology. Dr. O'Brien's publication record demonstrates expertise across multiple disciplines including diabetes research using feline models, lung cancer heterogeneity, and innovative transplantation techniques. His work frequently involves interdisciplinary collaborations across veterinary medicine, engineering, and human medical specialties, reflecting the integrative nature of modern biomedical research. His research program involves extensive collaborations across the University of Minnesota and beyond, working on projects related to stem cell biology, cancer research, and transplantation medicine. As Division Head of Comparative Pathology, he oversees diagnostic pathology services while maintaining an active research program that contributes to advancing our understanding of disease mechanisms through comparative approaches.

• Stress Physiology
• Psychoneuroendocrinology
• Primate Behavior
• +۵ مورد دیگر

Jerrold S Meyer is a Professor in the College of Natural Sciences at the University of Massachusetts Amherst, where he maintains an active research program focused on stress physiology and neuroendocrinology. His laboratory is located in Tobin Hall (441 Tobin Hall, Amherst, MA 01003), and he can be reached at 413-545-2168. Dr. Meyer's research primarily investigates the physiological and behavioral effects of stress, with particular expertise in hair cortisol analysis as a biomarker for chronic stress exposure. His work spans multiple domains including Primate models of stress and early life adversity Developmental effects of stress on children Epigenetic changes related to early life experiences Refugee and immigrant stress physiology Methodological development for hair and nail cortisol measurement His recent publication record (2022-2025) demonstrates continued leadership in the field, with approximately 30 publications in the last three years. These works reveal several key trends: a growing emphasis on cross-generational effects of stress, increasing application of epigenetic analyses to primate models, expansion into human refugee populations, and methodological refinements in stress biomarker measurement. His research consistently bridges basic science with clinical and public health applications. Dr. Meyer maintains extensive collaborations with researchers across multiple institutions, particularly with Novak MA, Dettmer AM, and Tarullo AR in primate research, and with clinical researchers studying stress in vulnerable human populations. His work has been cited extensively, with several papers receiving over 100 citations, indicating significant impact in the fields of psychoneuroendocrinology and developmental stress research. His laboratory appears to focus on both non-human primate models (particularly rhesus macaques) and human populations across the lifespan, from infants to adults. The research integrates behavioral observation, physiological measurement, and increasingly, molecular analyses to understand the mechanisms through which early experiences shape later outcomes.

Soraya de Chadarevianمشاهده پروفایل

استاد

• History of Science
• History of Molecular Biology
• History of Medicine
• +۳ مورد دیگر

Soraya de Chadarevian serves as Professor in the Department of History and the Institute for Society and Genetics at the University of California, Los Angeles, where she bridges historical scholarship with contemporary bioscience through rigorous analysis of material practices and cultural contexts in the life sciences. Her academic trajectory spans over three decades with significant contributions to understanding molecular biology's development and human heredity's evolution from the nineteenth century to present. Her educational foundation includes a PhD in Philosophy from the University of Konstanz, Germany, and an Advanced degree (Diplom) in Biology from the University of Freiburg, Germany, providing unique interdisciplinary perspective. These qualifications enabled her dual expertise in scientific practice and philosophical inquiry that defines her scholarly approach. De Chadarevian's research centers on the intricate relationship between scientific practice and cultural context in the life sciences, with particular emphasis on visual and material dimensions of molecular biology and chromosome research. She examines how laboratory techniques, archival practices, and data systems shape biological knowledge, exploring themes like the microscope's role in heredity studies, genetic evidence in historical narratives, and pandemic responses. Her work reveals how scientific concepts like the double helix or human genome emerge through complex negotiations between technical possibilities, institutional frameworks, and societal concerns. Analysis of her recent publications shows a decisive shift toward contemporary scientific challenges including pandemic responses, data-intensive biology, and ethical dimensions of genetic research. While maintaining deep historical perspective, her scholarship increasingly engages with urgent present-day issues such as biobanking, forensic genetics, and the societal implications of genomic databases, demonstrating how historical understanding informs current scientific controversies. Her scientific recognition includes: National Science Foundation Scholar Award (2015-2021) Walther Rathenau Program Fellowship Max Planck Institute for History of Science Fellowship Fellowship at La Villette Fellowship at École des Hautes Études en Sciences Sociales Hamburg Institute for Social Research Fellowship Churchill College Cambridge Fellowship Institute for Advanced Studies in the Humanities Fellowship Research funding has been consistently secured through competitive grants, most notably the six-year NSF award supporting her chromosome history project. She actively mentors students through UCLA's graduate programs in History and the Institute for Society and Genetics, teaching specialized courses on genetics and society while supervising research on science-society intersections. Her collaborative approach extends to co-editing special journal issues and organizing international research networks. Through sustained engagement with institutions like the Max Planck Society and Cambridge University, de Chadarevian maintains active participation in global scholarly communities. Her current work involves interdisciplinary teams examining data practices in contemporary biology and historical dimensions of pandemic responses, positioning her at the forefront of science studies' engagement with pressing societal challenges.

• Neuroscience
• Olfactory System
• Central Nervous System Development
• +۴ مورد دیگر

Charles A. Greer is Professor of Neurosurgery and Neuroscience at Yale School of Medicine, where he serves as Co-Vice Chair of Research for Neurosurgery and Director of the Yale Interdepartmental Neuroscience Graduate Program. He maintains joint appointments in both the Department of Neurosurgery and Department of Neuroscience, with additional affiliations through the Wu Tsai Institute, Yale Combined Program in the Biological and Biomedical Sciences, and Yale Stem Cell Center. Dr. Greer's research focuses on understanding the fundamental mechanisms that establish orderly topographic maps within the central nervous system during development and regeneration. His laboratory primarily investigates the complex olfactory system, studying how axons sort into functional subsets and target specific regions in the olfactory bulb. His work has significant implications for understanding neural regeneration following injury or disease, particularly through his research on ensheathing cells that support axon growth and can promote remyelination in damaged spinal cord tissue. His research spans multiple disciplines including neuroanatomy, developmental neuroscience, and neural regeneration, with particular emphasis on the molecular and cellular mechanisms of axon targeting, glial cell function, and neural circuit formation. Dr. Greer has established extensive collaborations across Yale departments including Neurology, Neurobiology, Anesthesiology, and Ophthalmology, as well as with institutions including Columbia University, Emory University, The Rockefeller University, University of Maryland, and University of Colorado. Dr. Greer has received numerous prestigious awards including the Max Mozell Award for Outstanding Achievements in the Chemical Senses, the R.H. Wright Award for Outstanding Research in Olfaction, and recognition as Distinguished Professor from Universite Pierre et Marie Curie in Paris. He has served as President of the Association for Chemoreception Sciences and as a member of NIH study sections and the Advisory Council for the National Institute on Deafness and Other Communication Disorders. As an educator, Dr. Greer has directed the Yale Interdepartmental Neuroscience Graduate Program and mentored numerous students and postdoctoral fellows. He serves as Associate Editor for The Journal of Comparative Neurology and Journal of Neuroscience, and sits on the editorial boards of several other neuroscience journals. His extensive publication record demonstrates sustained contributions to understanding the organization and development of neural systems, particularly the olfactory pathway.

• Tumor Glycocalyx Targeting
• Protease-Activated Anticancer Prodrugs
• Cancer Drug Development
• +۴ مورد دیگر

Robert Falconer serves as Professor of Medicinal Chemistry and Director of the Institute of Cancer Therapeutics (ICT) at the University of Bradford. A registered pharmacist with the General Pharmaceutical Council, he leads a multidisciplinary research team focused on tumor glycocalyx targeting and protease-activated anticancer prodrugs. His academic journey spans from pharmacy training at The School of Pharmacy, University of London to establishing the medicinal chemistry program at ICT in 2005. Pharmacy Degree: The School of Pharmacy, University of London (now UCL School of Pharmacy) PhD in Medicinal Chemistry: London (2000) Professional Registration: General Pharmaceutical Council Professor Falconer's research centers on tumor glycocalyx modulation through polysialyltransferase inhibition and protease-activated drug delivery systems. His work spans osteosarcoma, neuroblastoma, breast, and prostate cancers with emphasis on developing targeted therapies that minimize systemic toxicity. The Falconer group employs computational design, solid-phase synthesis, and advanced biological evaluation techniques to develop novel anticancer agents. His publication portfolio demonstrates consistent focus on tumor-specific activation mechanisms (2023-2025), glycocalyx-targeted metastasis inhibition (2019-2021), and prodrug development (2010-2014). Recent work emphasizes theranostic applications and DNA repair targeting for pediatric cancers. Fellow of the Royal Society of Chemistry Former Honorary Treasurer, RSC Central Yorkshire Local Section Trust (2012-2018) Registered Pharmacist with General Pharmaceutical Council As principal investigator, Falconer has secured substantial funding from Breast Cancer Now, Bone Cancer Research Trust, Worldwide Cancer Research, and Neuroblastoma UK. He leads the £2m ICT Doctoral Training Centre and co-founded spin-out company Incanthera plc, which is advancing the MMP-targeted prodrug ICT2588 to clinical trials. His mentorship includes three PhD students and multiple postdoctoral researchers developing next-generation cancer therapeutics. The Falconer group operates within the ICT's state-of-the-art facilities, collaborating with Stanford University, University of Sheffield, and Ellipses Pharma. Current projects address unmet needs in pediatric oncology while developing platform technologies applicable across multiple cancer types.

Kristopher Kilianمشاهده پروفایل

استاد

• Biomaterials
• Tissue Engineering
• Cell Plasticity
• +۷ مورد دیگر

Professor Kristopher Kilian is Director of the Laboratory for Advanced Biomaterials & Matrix Engineering (LAB&ME) with a joint position across the School of Chemistry and the School of Materials Science & Engineering in the Faculty of Science at UNSW Sydney. He serves as co-Director of the Australian Centre for NanoMedicine (ACN) and is a member of the Adult Cancer Program in the Prince of Wales Clinical School. His interdisciplinary research focuses on unraveling 'matrix structure-cell function' relationships through innovative biomaterial design. After completing his PhD at the University of New South Wales, Kilian pursued NIH postdoctoral training at the University of Chicago before faculty positions at the University of Illinois at Urbana-Champaign (2011-2018). He returned to UNSW in 2018 as a Scientia Fellow, establishing his current leadership roles. Research Focus: Design of model extracellular matrices and dynamic hydrogels for cell and tissue engineering Fundamental studies in cell plasticity and matrix-directed cell fate Development of synthetic tumor microenvironments for drug testing iPSC-derived organoid bioengineering 4D biofabrication techniques Tissue engineering approaches for lab-grown meat applications His extensive publication record demonstrates consistent focus on hydrogel mechanics, dynamic biomaterials, and the role of physical cues in directing cell behavior. Recent work emphasizes mechanochemistry, spatial control of cell differentiation, and the development of sophisticated tumor models that replicate the complexity of cancer microenvironments. Scientific Recognition: Cornforth Medal (2008) NIH Ruth L. Kirchstein Award (2008) Kavli Fellow (2014) NSF CAREER Award (2015) Australian Research Council Future Fellowship (2018) Eureka Prize finalist (2023) Kilian's research program bridges fundamental cell biology with translational applications, particularly in cancer modeling and regenerative medicine. His laboratory develops innovative biomaterial platforms that enable precise control over cellular microenvironments, facilitating discoveries in cell plasticity and tissue engineering. The group's work on dynamic hydrogels and mechanochemical systems represents a significant contribution to the field of biomaterials science. As Director of LAB&ME, Kilian leads a multidisciplinary team that integrates nano- and micro-fabrication techniques with synthetic chemistry to create biomimetic materials. The laboratory's approach centers on the concept that cell state and fate are governed by inherent cell plasticity within specific multivariate signaling contexts.

Meden F. Isaac-Lamمشاهده پروفایل

استاد

• Drug therapeutics for cancer
• Photodynamic therapy
• Triple-negative breast cancer treatment
• +۱۰ مورد دیگر

Meden F. Isaac-Lam is a Professor of Chemistry in the College of Engineering and Sciences at Purdue University Northwest, where she teaches organic chemistry, biochemistry and general chemistry. Her research spans multiple interdisciplinary fields with significant contributions to cancer therapeutics and molecular imaging. Her primary research interests focus on the development and discovery of drug therapeutics for photodynamic therapy as cancer treatment and for neurodegenerative diseases, the use of MRI/MRS (magnetic resonance imaging and spectroscopy) to study brain diseases and disorders, and understanding the effect of calorie restriction in human health . Additional research areas include plastic degradation, environmental protection, and STEM education innovation. Dr. Isaac-Lam's scholarly work demonstrates a strong trend toward translational research with clinical applications, particularly in cancer treatment. Her publications show expertise in chemical synthesis, molecular imaging, and therapeutic development with a focus on practical applications for human health conditions. Senior Fulbright Scholar United States Patent No. 11,191,835 B2 for Chlorin-Vitamin Conjugates (Therapeutics for Cancer) Dr. Isaac-Lam is deeply committed to mentoring undergraduate students, believing that "mentoring is extremely critical in student success." She emphasizes individualized teaching approaches and has developed well-structured mentoring programs that consider students' career paths and intellectual abilities. Her patent work serves as an inspiration for students, demonstrating the real-world applications of chemistry research and the possibility of becoming an inventor. She leads interdisciplinary research initiatives including a project studying American military veterans afflicted with post-traumatic stress disorder (PTSD), collaborating with statisticians, social workers, psychologists, radiologists, MRI technicians and medical physics students to understand how brain molecules affect feelings and behavior.

Tom Wenseleersمشاهده پروفایل

استاد

• Theoretical Biology
• Evolutionary Biology
• Behavioural Ecology
• +۷ مورد دیگر

Tom Wenseleers is a Professor at KU Leuven's Department of Biology within the Faculty of Science, where he leads the Laboratory of Socioecology and Social Evolution. His research spans theoretical and experimental approaches to evolutionary biology, with particular focus on social insect systems. Research spans social insects (ants, bees, wasps), microbes, viruses, and human systems Primary model organisms: social insects studying major evolutionary transitions Current projects examine caste determination, chemical communication, and evolutionary conflicts His research integrates theoretical modeling with experimental, behavioral, and comparative studies. Recent work combines genomic techniques and high-throughput GC/MS analysis to decipher chemical communication systems. Current trends show increasing interdisciplinary work spanning virology (SARS-CoV-2 variants), microbial ecology (antibiotic resistance), and robotics (pollinator behavior monitoring). The research demonstrates consistent application of evolutionary theory to diverse biological systems while maintaining social insects as the core model. Wenseleers actively mentors PhD students and postdocs, with recent graduates including Kamiel Debeuckelaere and Viviana Di Pietro. His lab receives substantial funding through multiple concurrent research projects, including Promotor roles on grants examining caste development in bee societies and microbial metabolite screening. The laboratory maintains strong international collaborations across Europe and South America. The lab operates within the Ecology, Evolution and Biodiversity Conservation unit at KU Leuven, with physical location at Naamsestraat 59, box 2466, 3000 Leuven. The research group maintains active outreach programs including science workshops for schools and public engagement events focused on insect conservation.

Elizabeth T Bartomمشاهده پروفایل

دانشیار

• Computational Biology
• Genomics
• Transcriptional Regulation
• +۳ مورد دیگر

Elizabeth T Bartom, PhD is an Associate Professor in the Department of Biochemistry and Molecular Genetics at the Feinberg School of Medicine, Northwestern University. She is affiliated with the Simpson Querrey Institute for Epigenetics, Center for Genetic Medicine, and Robert H. Lurie Comprehensive Cancer Center. PhD: Cold Spring Harbor Laboratory (2004) Postdoctoral Fellow: Harvard University and Broad Institute (2006–2010) Her research focuses on chromatin organization , transcriptional regulation , and genomic integrity in cancer and immunobiology. Recent work explores 3D genome effects in bladder cancer and pediatric brain tumors, lipid metabolism in breast cancer, and novel genomic labeling techniques. R50 Research Specialist Award, National Cancer Institute (2023) Outstanding Teacher Award, Feinberg School of Medicine (2021) Dean’s Teaching Award, Driskill Graduate Program (2019) She is a member of the Robert H Lurie Comprehensive Cancer Center (2020–present) and Simpson Querrey Center for Epigenetics (2018–present), with expertise in computational biology and genomics.

Lee Fergusonمشاهده پروفایل

استاد

• Environmental Analytical Chemistry
• High-Resolution Mass Spectrometry
• Per- and Polyfluoroalkyl Substances (PFAS)
• +۳ مورد دیگر

Lee Ferguson is a Professor of Civil and Environmental Engineering at Duke University, with additional appointments as Associate Professor in the Division of Marine Science and Policy. His research focuses on environmental analytical chemistry, particularly using high-resolution mass spectrometry to study per- and polyfluoroalkyl substances (PFAS) , microplastics , and endocrine disruptors . Ferguson Lab develops methods for contaminant detection in water systems and investigates chemical leaching from polymers. Ph.D. in Chemistry from Stony Brook University (2002) Former Assistant Professor at University of South Carolina (2003-2009) Recent work includes PFAS analysis in lithium-ion batteries, glyphosate detection in hard waters, and microplastic dye toxicity studies. Key publications explore urban watershed contamination, Sri Lankan drinking water CKDu links, and novel analytical methods for environmental pollutants. Applied Research Fellowship (2022), Kavli Frontiers of Science Fellow (2011) Testified before U.S. Senate on nanotechnology risks Co-founder of NC PFAS Testing Network As an advisor, he mentors Doctoral Candidates Patrick Faught and Anna Lewis , who investigate microplastic dyes and polymer additives. Lab research spans environmental fate of nanomaterials, contaminant bioavailability, and exposomics for health outcomes.

Niklas Mattsson-Carlgrenمشاهده پروفایل

دانشیار

• Alzheimer's Disease
• Neurodegenerative Diseases
• Tau Pathology
• +۷ مورد دیگر

Niklas Mattsson-Carlgren serves as an Associate Professor and Senior Lecturer at Lund University's Faculty of Medicine, Department of Clinical Sciences. He holds multiple significant roles including Deputy Research Team Manager and Principal Investigator for several major research projects. His affiliations extend to the Wallenberg Centre for Molecular Medicine (WCMM), LU Profile Area: Proactive Ageing, and MultiPark: Multidisciplinary Research Focused on Parkinson's Disease. Dr. Mattsson-Carlgren's research primarily focuses on Alzheimer's disease and other neurodegenerative conditions, with additional work on acute brain injuries such as those following cardiac arrest. His expertise spans neurochemistry, including the regulation of pain and sleep. He employs biochemical measurements, neuroimaging, and cognitive testing to study disease processes in vivo across the spectrum from preclinical disease to advanced dementia. His work aims to improve diagnostic and prognostic methods in clinical practice, enhance clinical trial design for novel therapies, and deepen understanding of disease mechanisms. His recent publications demonstrate a strong emphasis on plasma biomarkers for Alzheimer's disease detection and monitoring, with particular focus on tau and amyloid pathology. The research shows increasing integration of machine learning approaches with traditional biomarker analysis, reflecting a trend toward more sophisticated diagnostic tools that combine multiple data sources for improved accuracy in predicting disease progression. As Principal Investigator for multiple significant projects including 'Longitudinal plasma biomarkers, cognitive data and amyloid PET to improve early prevention of Alzheimer's disease' and 'Validation of an MTBR tau immunoassay for CSF and plasma,' he leads substantial research efforts funded by organizations including Familjen Rönströms stiftelse, Eli Lilly and Company, and the Knut and Alice Wallenberg Foundation. He also serves as supervisor for PhD students, notably for 'Studies of induced neuronal cells in Alzheimer's disease.' Dr. Mattsson-Carlgren is actively involved in the neuroscience community, serving on the program committee for Neuroscience Day 2025. His research contributes to UN Sustainable Development Goals related to health and wellbeing. His work has gained significant attention, with multiple papers being picked up by news outlets and referenced across social media platforms including X (Twitter) and Bluesky.

Paul Rothemundمشاهده پروفایل

دانشگاهی

• DNA Nanotechnology
• Molecular Biology
• Biochemistry
• +۴ مورد دیگر

Paul Rothemund is a Visiting Associate in Computing and Mathematical Sciences and Computation & Neural Systems at the California Institute of Technology . His research focuses on expanding the toolkit of DNA nanotechnology , particularly through the development of DNA origami and its integration into fields like biological engineering and translational research . He is part of the Biology and Biological Engineering divisions and collaborates with the Winfree and Qian labs. B.S., Caltech (1994) Ph.D., University of Southern California (2001) Research Interests Rothemund’s work centers on programmable molecular systems , with a focus on DNA origami for creating nanoscale shapes, RNA nanostructures , and lipid nanodiscs . His lab develops methods for molecular self-assembly , nanophotonic architectures , and single-molecule assays . Key applications include hybrid nanodevices , precision biomolecular placement , and dynamic DNA/RNA systems . Publication Trends Over 15 recent articles, Rothemund’s research spans DNA/RNA origami , lipid bilayer engineering , nanoarray fabrication , and biomolecular sensing . Themes include modular design , co-transcriptional folding , and programmable nanoscale materials . Scientific Recognition Beckman Senior Research Fellow (2001-04) Bryan R. Coles Prize (2017) Advising & Collaborations Rothemund has advised doctoral students and postdocs such as Anya Mitskovets (now at KLA) and Tyler Ross (MIT/Harvard). His lab forms a DNA nanotechnology supergroup and engages in interdisciplinary collaborations.

Hans-Guido Wendelمشاهده پروفایل

دانشیار

• Cancer Biology
• Lymphoma
• Leukemia
• +۷ مورد دیگر

Hans-Guido Wendel is an Associate Professor at the Graduate School of Medical Sciences, Weill Cornell Medicine, and a Member at the Sloan-Kettering Institute. His research is centered on uncovering biological vulnerabilities in cancer cells, particularly in aggressive lymphomas and leukemias, to develop novel therapeutics. His research interests span several critical areas in cancer biology, including: Immune receptor signaling in lymphoma Oncogenic RNA translation programs Epigenetic and transcriptional regulation in cancer Metabolic control of gene expression CRISPR-based discovery of cancer dependencies He leverages cutting-edge tools such as unbiased CRISPR/Cas9 screens and patient-derived xenograft models to validate therapeutic targets. The trends in his research, as reflected in key publications, emphasize the translation of molecular discoveries into clinical strategies. His work bridges basic mechanisms—such as glucose-regulated transcription and RNA helicase function—with therapeutic innovation, including small molecule inhibitors and engineered immune cells like CAR T 'micro-pharmacies'. These efforts highlight a consistent focus on target identification and validation in hematologic malignancies. Scientific recognition includes: National Cancer Institute Outstanding Investigator Dr. Wendel leads an active research program supported by institutional and federal funding. His lab mentors trainees and collaborates across disciplines to advance cancer therapeutics. Though no specific students are listed, his team conducts high-impact research in target discovery and preclinical validation. Future work includes developing inhibitors for glucose-regulated transcription and refining immune cell engineering for solid and hematologic tumors. His laboratory, known as the VIVO Lab, operates at the interface of molecular oncology and translational medicine, contributing to both fundamental understanding and therapeutic innovation in cancer biology.