جستجوی استاد راهنمای دانشگاهی

Konstantinos Anastassiadis is a Professor at the Center for Molecular and Cellular Bioengineering (CMCB) of Dresden University of Technology , leading the Stem Cell Engineering group at the Biotechnology Center (BIOTEC) . His research focuses on unraveling molecular pathways regulating stem cell self-renewal and lineage commitment, with a strong emphasis on genetic engineering tool development and epigenetic mechanisms during cellular reprogramming. The lab utilizes mouse and human embryonic stem cells, neural stem cells, mesenchymal stromal cells, and induced pluripotent stem cells (iPSCs) in their investigations. Core Research Areas: Molecular regulation of stem cell fate Epigenetic mechanisms (e.g., UTX/UTY histone demethylases) Genetic engineering tool development (Flp, Dre, Vika recombinases, CRISPR protocols) Conditional immortalization systems for rare cell expansion Publications highlight his contributions to understanding: Role of histone methyltransferases (MLL1, MLL2, Setd1b) in hematopoiesis and cancer Epigenetic regulation during mouse development and spermatogenesis Genetic tools for protein tagging, transposon-mediated BAC transgenesis Interactions between stem cells and niche microenvironments Transcriptional and mechanical markers during reprogramming Collaborations span immunology , developmental biology , and bioinformatics . The lab actively participates in teaching activities at CMCB and maintains a focus on translational applications of stem cell research.

• Stem Cell Biology
• Genetic Engineering
• Epigenetics
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Omer Bayraktar is a Group Leader at the Wellcome Sanger Institute , leading research in the Cellular Genomics Programme. His work focuses on decoding human brain cellular diversity using spatial transcriptomics , imaging , and functional screening to study neural complexity in health and disease. Bayraktar's educational background includes a PhD from HHMI under Chris Doe, investigating neural diversity development in Drosophila , followed by postdoctoral work at University of California, San Francisco and University of Cambridge as a Life Sciences Research Foundation Fellow. He developed a spatial transcriptomic pipeline during his postdoc to analyze astrocyte heterogeneity in the cerebral cortex. His research explores neural cell type mapping , glial-neuronal interactions , and cellular pathways in neurodevelopmental disorders . Recent publications emphasize 3D tissue mapping , multi-omic integration , and computational tools like Cell2fate and WebAtlas. His work bridges neurogenetics and computational biology to advance understanding of human tissue ecosystems. Bayraktar's lab collaborates with the Human Cell Atlas initiative and develops technologies such as automated histology pipelines and highly-multiplexed smFISH for molecular cell typing. His team also investigates glia-based therapies and astrocyte functional heterogeneity in neurodevelopmental contexts. Key scientific contributions include: Discovering astrocyte layer patterns independent of neuronal laminae Developing cell2location for spatial cell mapping Characterizing Drosophila neural stem cell models with human relevance Notable awards include the Life Sciences Research Foundation Fellowship during his postdoctoral training. His current group includes a PhD student , Senior Data Scientists , and Bioinformaticians .

• Neural Diversity
• Spatial Transcriptomics
• Glia Biology
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Martin Gosau is a Professor at the Clinic and Polyclinic for Oral and Maxillofacial Surgery within the Medical Faculty of the University Medical Center Hamburg-Eppendorf (UKE). His research focuses on Oral Surgery , Maxillofacial Surgery , and Regenerative Medicine , with a strong emphasis on Dental Implants , Head and Neck Cancer , and Oral Pathology . University: University Medical Center Hamburg-Eppendorf School: Medical Faculty Department: Oral and Maxillofacial Surgery Academic Rank: Professor His recent work explores: Oral Health in Genetic Disorders (e.g., hypophosphatasia) Advanced Surgical Techniques (e.g., nanosecond lasers, fluorescence angiography) Biomaterials and Tissue Engineering (e.g., silk fibroin membranes, extracellular vesicles) Cancer Prognostics (e.g., DCBLD1 overexpression in HNSCC) Key trends in his 15 most recent articles include applications of machine learning in oral diagnostics, stem cell research for bone regeneration, and biomaterials in reconstructive surgery. He frequently collaborates with Ralf Smeets and Thomas Vollkommer , with publications spanning Frontiers in Immunology , Oral Surgery , and Scientific Reports .

• Oral Surgery
• Maxillofacial Surgery
• Head and Neck Cancer
• +۱۲ مورد دیگر

Dr. Timur Alexander Yorgan is a prominent researcher at the Department of Osteology and Biomechanics at University Medical Center Hamburg-Eppendorf (UKE). Holding a Dr. rer. nat. degree, he has established himself as a leading figure in bone biology with over 60 publications spanning from 2013 to 2025. His research is deeply integrated with key institutional research areas including the Hamburg Center of Neuroscience and immunology research networks at UKE. Dr. Yorgan's research focuses on skeletal development, bone remodeling, and genetic bone disorders, with particular emphasis on Wnt signaling pathways and their role in bone homeostasis. His work spans multiple approaches from molecular genetics to translational studies, investigating osteoblast and osteocyte biology, genetic mechanisms underlying disorders like osteogenesis imperfecta, and the effects of various mutations on skeletal integrity. Recent research has expanded into the gut-bone axis, mechanobiology of bone cells, and neuro-immune interactions affecting bone metabolism. Analysis of Dr. Yorgan's publication record reveals a consistent trajectory of high-impact research in bone biology. His work increasingly explores interdisciplinary connections between bone metabolism and other physiological systems, with growing emphasis on translational approaches for therapeutic interventions. The research demonstrates sophisticated use of mouse models and molecular techniques to unravel complex bone disorders and identify potential treatment targets. Dr. Yorgan appears to be actively involved in collaborative research across multiple institutions, as evidenced by his extensive publication record with numerous co-authors from various departments and institutions. His work is frequently published in high-impact journals including Journal of Bone and Mineral Research, Nature Communications, and Bone Research. The Department of Osteology and Biomechanics at UKE, where Dr. Yorgan is based, is part of a vibrant research ecosystem that includes the Hamburg Center of Neuroscience and other key research networks focusing on immunology, oncology, and cardiovascular research. This collaborative environment enables interdisciplinary approaches to understanding skeletal disorders and developing novel therapeutic strategies.

• Bone Biology
• Skeletal Disorders
• Wnt Signaling Pathways
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Rex Hung is an Associate Professor of Pathology at Harvard Medical School and serves as an Associate Pathologist at Massachusetts General Hospital . His academic career focuses on Bone and Soft Tissue Pathology , Cardiovascular Pathology , and Pulmonary Pathology , with significant contributions to cancer research.

• Bone and Soft Tissue Pathology
• Cardiovascular Pathology
• Pulmonary Pathology
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G. Petur Nielsen, MD is a Professor of Pathology at Harvard Medical School and serves as Subspecialty Head, Bone and Soft Tissue Pathology at Massachusetts General Hospital . With a clinical focus on bone and soft tissue tumors, his expertise spans diagnostic pathology, molecular genetics of neoplasms, and ancillary testing applications. Research interests center on Pathology and biology of bone/soft tissue tumors Molecular genetics of bone and soft tissue neoplasms Chordoma and sarcoma research Epithelioid vascular tumor differentiation Mesenchymal tumors of the female genital tract His work includes landmark studies on tumor misdiagnosis rates, immunohistochemical profiling, and genomic analysis of chordomas. Scientific contributions appear in leading journals like Nature and American Journal of Surgical Pathology , with major emphasis on Molecular tumor classification Mutational signature analysis Translational oncology Diagnostic accuracy improvement Genomic instability mechanisms

• Bone and Soft Tissue Pathology
• Molecular Genetics of Bone Tumors
• Chordoma Research
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Sonja Schelhaas is a researcher affiliated with the European Institute for Molecular Imaging (EIMI) at the University of Münster. Her work focuses on molecular imaging technologies, particularly in oncology and neurological contexts. PhD in Medical Biochemistry (2007-2010) Postdoc at EIMI since 2010 Research Fellow in Anaesthesiology (2005-2006) Her research spans: PET tracer development for ion channels Molecular imaging of tumor microenvironments Applications of small animal PET in disease models Bacterial and inflammatory imaging Radiochemistry and multimodal imaging techniques Epigenetic regulation in cancer Recent publications highlight her contributions to: P2X4 receptor antagonists for PET tracers KCa31 channel imaging in cancer Bacterial detection via radiolabeled compounds FLT PET for tumor proliferation analysis Neurogenesis and blood-brain barrier studies PEGylated nanoparticle characterization Schelhaas has collaborated extensively in preclinical imaging projects, contributing to cancer research, infection monitoring, and neurodegenerative disease modeling. Her work appears in journals like Journal of Medical Chemistry , Cancer Research , and Molecular Imaging and Biology .

• Molecular Imaging
• Optical Imaging
• Molecular Biology
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Prof. Dr. Jörn Walter serves as a Senior Professor for Genetics and Epigenetics at Saarland University's Faculty of Natural Sciences and Technology. His laboratory investigates epigenetic mechanisms across development and disease states, with particular emphasis on DNA methylation, chromatin dynamics, and epigenomic mapping of cell types. Member of the International Human Epigenome Consortium (IHEC) Coordinator of the German Epigenome Program Director of an in-house Sequencing Facility (HiSeq2500, Mi-Seq, Nextseq-500) Research focuses include: Epigenetic programming during cellular differentiation DNA methylation dynamics in disease contexts Stem cell epigenetics and reprogramming Evolution of epigenetic mechanisms Recent publications highlight interdisciplinary approaches combining next-generation sequencing , bioinformatic modeling , and clinical epigenetics , with particular attention to immune cell development , metabolic disease epigenetics , and computational epigenomics . The group maintains collaborations with the West German Sequencing Center and contributes to epigenetic data standardization efforts. Lab members include active researchers like Dr. Nina Gasparoni , Dr. Gilles Gasparoni , and M.Sc. Alea Leismann , alongside an extensive alumni network of former advisees who have advanced epigenetic research in various institutions.

• Epigenetics
• Genetics
• Epigenomics
• +۵ مورد دیگر

Thorsten Schinke is a full-time faculty member and Professor at the Department of Osteology and Biomechanics , University of Hamburg-Eppendorf (UKE). His research focuses on molecular mechanisms of bone remodeling, Wnt/Notch signaling, osteoimmunology, and genetic factors in skeletal disorders. Key Research Themes: Wnt Signaling, Osteoporosis, Osteoimmunology, Skeletal Metastasis, Genetic Bone Diseases, Osteal Macrophages Scientific Contributions: Schinke has led 8 DFG-funded projects (2010-2021) exploring interactions between bone remodeling and disease states. His work includes identifying novel roles for Rsk2, PLS3, and Notch2 in osteosarcoma progression, X-linked osteoporosis, and Hajdu-Cheney syndrome. Using genetically engineered mouse models, he established connections between cytokine signaling (e.g., IL17, S1P), lysosomal dysfunction, and skeletal pathology. Recent Trends: Analysis of 15 recent publications (2017-2021) reveals expertise in in vivo bone modeling, histomorphometry, and cross-disciplinary approaches combining immunology and bone biology. Key subfields include tumor-bone interactions, Wnt-stimulated anabolism, and metabolic regulation of osteoblast/osteoclast balance. Scientific Awards: DFG Project 401122336 (2018-2021) DFG Project 385501541 (2017-2021) DFG Project 278045702 (2015-2019) DFG Project 235869912 (2013-2017) DFG Project 27463524 (2010-2014) Contact: Research conducted at Campus Lehre N55, Martinistrasse 52, Hamburg. Email: fis@uke.de

• Osteology
• Biomechanics
• Bone Remodeling
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Professor Jochen Gaedcke is an active surgical oncology specialist at University Medical Center Göttingen's Faculty of Medicine, Department of Surgery. His supervisory role spans 15 doctoral theses from 2017-2025, demonstrating his sustained academic leadership in gastrointestinal and cancer research. Position: Professor of Surgery Supervision Period: 2017-2025 (ongoing) Thesis Topics: Primarily focused on gastrointestinal malignancies and surgical outcomes Professor Gaedcke's research centers on surgical oncology with particular emphasis on pancreatic and colorectal cancers. His work investigates tumor microenvironment characteristics (particularly fibrosis in pancreatic cancer), molecular mechanisms of treatment response (KRAS mutations, p53 pathways), and clinical outcomes following gastrointestinal procedures. His supervision portfolio reveals a consistent focus on improving diagnostic methods, treatment efficacy, and complication management in visceral surgery. Analysis of his supervised publications shows a strong trend toward translational research bridging basic science discoveries with clinical applications. Approximately 60% of the theses focus on gastrointestinal cancers (pancreatic, colorectal, gastric), 25% on surgical complications and outcomes, and 15% on diagnostic innovations. The work demonstrates increasing sophistication in molecular analysis techniques over time, with recent theses incorporating advanced biomarker discovery and personalized treatment approaches. Professor Gaedcke has supervised 15 doctoral candidates to completion between 2017-2025, indicating a robust mentoring program. His students have investigated diverse aspects of surgical oncology, with several focusing on pancreatic cancer (3 theses), colorectal cancer (4 theses), and diagnostic methods (3 theses). This mentoring activity demonstrates his central role in training the next generation of surgical researchers in Germany. His laboratory work appears to focus on tumor microenvironment analysis, particularly the role of fibrosis in pancreatic cancer progression and treatment response. The collaborative nature of his work is evident from co-authorship on multiple publications with colleagues across pathology, molecular biology, and clinical departments.

• Surgical Oncology
• Gastrointestinal Surgery
• Pancreatic Cancer
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Professor Stefan Fröhling serves as Managing Director of the National Center for Tumor Diseases (NCT) Heidelberg and heads the Division of Translational Medical Oncology at the German Cancer Research Center (DKFZ). His research focuses on precision oncology, molecular characterization of tumors, and clinical trials for targeted therapies. 2020: Managing Director, NCT Heidelberg 2019: Head of Division, Translational Medical Oncology, DKFZ 2012–present: Attending Physician, NCT Heidelberg/DKFZ and Heidelberg University Hospital Fröhling’s research emphasizes precision oncology through molecular profiling and functional characterization of tumors. Key areas include: Development of tools for tumor molecular analysis Clinical trials on molecularly targeted therapies Investigation of bone/soft-tissue sarcomas and leukemias Integration of genomic/transcriptomic data in treatment strategies His recent publications highlight work on: Targeting oncogenic dependencies in leukemia (e.g., RET-mediated autophagy) Molecular characterization of sarcomas (e.g., leiomyosarcoma genomics) Exploiting genetic alterations (KIT, FGFR1, BRAF) for therapeutic interventions Fröhling has received prestigious awards including: Uncommon Collaboration Award (2018) Young Investigator Fellowship (2009–2011) Research Fellowship from German Research Foundation (2005–2007) Leukemia Research Award (2004) As a clinician-scientist, Fröhling bridges translational research with clinical practice, contributing to advancing therapies for hematologic malignancies and sarcomas through interdisciplinary collaboration.

• Precision Oncology
• Molecular Targeted Therapies
• Sarcoma Biology
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Dr. Johannes Greiner is a researcher at the Faculty of Biology at University of Bielefeld, Germany, with a strong research focus on stem cell biology, particularly neural crest-derived stem cells and their molecular regulation. His work bridges fundamental cellular mechanisms with potential clinical applications in regenerative medicine and cancer therapy. Dr. Greiner's primary research interests include: Neural crest-derived stem cell characterization and differentiation pathways NF-κB signaling mechanisms in stem cells and disease contexts Sex-specific differences in stem cell behavior and differentiation potential Osteogenic and neuronal differentiation processes Cancer stem cell biology and therapeutic targeting strategies Analysis of Dr. Greiner's publication record from 2011-2024 reveals a consistent research trajectory focused on molecular mechanisms governing stem cell behavior, with particular emphasis on NF-κB pathway regulation and sex-based differences in cellular responses. His work demonstrates methodological diversity, employing techniques ranging from single-cell analysis to molecular pathway interrogation, reflecting a comprehensive approach to understanding stem cell function in both health and disease contexts. Dr. Greiner has contributed to numerous publications in specialized journals focusing on molecular biology, regenerative medicine, and cancer research, with collaborative work spanning multiple research groups. His research output demonstrates sustained productivity and evolving focus toward understanding the fundamental mechanisms that govern stem cell behavior and their implications for human health.

• Stem Cell Research
• Neural Crest-Derived Stem Cells
• NF-κB Signaling
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Sibylle Maria Kneissl serves as Professor of Diagnostic Imaging at the University of Veterinary Medicine Vienna, holding concurrent roles as senior clinician (Oberarzt) since 2011 and Specialty Chief Editor for Veterinary Imaging at Frontiers in Veterinary Science. Appointed Professor in 2008 after serving as Assistant Professor, she maintains active research and editorial leadership within veterinary academic medicine. Her educational foundation includes graduation from the University of Veterinary Medicine Vienna in 1992 with specialized training in anatomy, oncology, and diagnostic imaging. This background established her trajectory in veterinary clinical sciences and imaging diagnostics. Research centers on advanced veterinary imaging techniques for small animals, with significant contributions to feline oncology , canine orthopedic diagnostics , and neuroanatomical studies . Her work bridges clinical practice and educational innovation, particularly through flipped classroom methodologies for veterinary imaging education. Current investigations focus on autoimmune disease modeling, craniocervical pathologies, and thoracic computed tomography validation against surgical findings. Recent publications (2022-2025) reveal concentrated expertise in imaging technology evolution, with 81 total publications demonstrating consistent output in veterinary diagnostic journals. Key trends include species-specific imaging protocols (dogs/cats), translational oncology models, and educational assessment frameworks for veterinary curricula. As Specialty Chief Editor for Veterinary Imaging at Frontiers in Veterinary Science, she shapes scholarly discourse in her field while maintaining active clinical and research engagement. Her editorial leadership complements ongoing clinical work as senior clinician in diagnostic imaging.

• Veterinary Diagnostic Imaging
• Veterinary Oncology
• Veterinary Anatomy
• +۲ مورد دیگر

Lydia Sorokin is a Professor at the Institute of Physiological Chemistry and Pathobiochemistry within the University of Münster , Germany. She serves as Spokesperson for the Cells in Motion Interfaculty Centre and actively contributes to the Imaging Network and CiM-IMPRS graduate program . Research Focus: Cell-matrix interactions, leukocyte extravasation, blood vessel biology, secondary lymphoid organs, and neuroinflammatory processes. Key Contributions: Elucidating laminin functions in vascular integrity, neuroinflammatory disease mechanisms, and extracellular matrix regulation of immune cell migration. Publication Trends: Recent studies (2022-2024) explore CNS macrophage heterogeneity , endothelial-laminin interactions , and neurovascular unit dysfunction in diseases like multiple sclerosis and cerebral small vessel disease. Earlier work (2012-2020) established roles for laminins and matrix metalloproteinases in blood-brain barrier regulation, immune cell trafficking, and tissue-specific matrix responses. Collaborations & Networks: Active in Cells in Motion , Imaging Network , and CiM-IMPRS graduate program. Collaborates with institutions across Europe on neurovascular and immunology research. Contact: sorokin@uni-muenster.de

• cell-matrix interactions
• leukocyte extravasation
• blood vessels
• +۴ مورد دیگر

Katharina Harms-Effenberger is the Head of Research Group at the Institute of Tumor Biology within the Center for Experimental Medicine at the University Medical Center Hamburg-Eppendorf (UKE). She specializes in oncology and molecular diagnostics, focusing on cancer biomarkers, liquid biopsy techniques, and metastasis mechanisms. Her work spans multiple cancers including cervical, pancreatic, esophageal, and lung cancers, with a strong emphasis on clinical applications and prognostic modeling. Her research integrates molecular pathology, genomic analysis, and clinical outcomes to improve diagnostic accuracy and patient stratification. Key areas include circulating tumor cells (CTCs), disseminated tumor cells (DTCs), and epigenetic biomarkers like DNA methylation. She collaborates with institutions like the European Liquid Biopsy Society (ELBS) to advance translational research. Publications highlight contributions to CTC-based risk stratification, liquid biopsy validation, and the role of genetic markers in cancer progression. Her work bridges basic science and clinical practice, aiming to translate molecular findings into actionable diagnostics and therapies.

• Cancer Research
• Oncology
• Molecular Biology
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