جست‌وجوی استاد و پژوهشگر

John E. Mosesمشاهده پروفایل

استاد

• Click Chemistry
• Cancer Drug Development
• Antibiotic Discovery
• +۴ مورد دیگر

John E. Moses is a Professor at Cold Spring Harbor Laboratory (CSHL), where he leads the Moses Laboratory and serves as Faculty Head of the Mass Spectrometry Shared Resource for the Cancer Center. He is also a Cancer Center Member focusing on developing chemical tools for biological discovery, particularly in cancer research. Dr. Moses earned his D.Phil. in Synthetic Organic Chemistry from the University of Oxford in 2004. His academic journey includes positions as Professor of Organic Chemistry at La Trobe University (2017-2020), Level 6 Future Fellow at the Australian Research Council (2017-2021), and Reader & Associate Professor in Organic Chemistry at the University of Nottingham (2007-2017). Moses' research focuses on click chemistry, a powerful discovery method that uses robust chemical reactions to synthesize functional molecules. His lab specializes in developing and exploiting bond-forming click reactions for rapid synthesis of small functional molecules, including cancer drugs and chemical probes. They apply these molecular tools in multidisciplinary projects spanning biology and chemistry. His recent work has led to significant advances in click chemistry methodologies, including Diversity Oriented Clicking (DOC) and Phosphorus Fluoride Exchange (PFEx). These approaches have enabled the discovery of new cancer therapeutics and antibiotics effective against multidrug-resistant bacteria like MRSA. Dr. Moses has received numerous honors including the 2021 Organic Division Horizon Prize: Robert Robinson Award in Synthetic Organic Chemistry, Fellow of the Royal Society of Chemistry (2015), Thieme Chemistry Award (2011), and UK & ROI Lilly Award for Excellence in Organic Chemistry (2011). Through his work at CSHL, Moses mentors students and postdoctoral researchers while collaborating with biologists to develop Chemistry For Biology. His lab's innovative approaches have been supported by multiple grants, including those from the National Cancer Institute. The Moses Laboratory is at the forefront of click chemistry research, developing new methodologies while applying them to solve critical problems in cancer biology and antibiotic resistance.

Markus Schwarzländerمشاهده پروفایل

استاد

• Plant Mitochondrial Physiology
• Redox Biology
• Biosensor Development
• +۳ مورد دیگر

Prof. Dr. Markus Schwarzländer leads the Arbeitsgruppe for Plant Energy Biology at the Institute for Plant Biology and Biotechnology (WWU Münster) . His research focuses on mitochondrial physiology, redox signaling, and biosensor development in Arabidopsis thaliana and other plant species, integrating molecular biology with systems-level analyses to understand energy regulation. Key Research Areas: Mitochondrial-NAD(P)H dynamics Redox-regulated signaling networks Organelle communication Stress-adaptive metabolism Recent work highlights Golgi-localized mitochondrial uncoupling proteins , chloroplast-mitochondria redox coupling , and mitochondrial calcium uniporter function . His group employs cutting-edge fluorescent biosensors and proteomic approaches to dissect energy physiology. Students benefit from hands-on training in bioimaging , metabolic modeling , and organelle biology through iMoPLANT and Life Sciences programs. Scientific Awards: DAAD Fellowship (2019) As an active member of the Faculty of Biology , he collaborates with international institutions including University of São Paulo , CEA France , and Siberian Institute of Plant Physiology , while maintaining a robust publication record in top journals like Plant Cell and Nature . His teaching emphasizes integrative plant sciences and advanced biosensing techniques for B.Sc. and M.Sc. students.

• Anthropological Genomics
• Paleogenomics
• Human Body Size Evolution
• +۷ مورد دیگر

George Perry is a Professor of Anthropology at Pennsylvania State University, with research intersections in Biology, Evolutionary Medicine, and Genomics. He is affiliated with the Huck Institutes' Center for Infectious Disease Dynamics, Ecology, Molecular Cellular and Integrative Biosciences, and Bioinformatics and Genomics programs. Perry directs the Anthropological Genomics Lab , focusing on paleogenomics and evolutionary adaptation. Research areas: anthropological genomics, parasite evolution, human body size transitions, and evolutionary medicine Key collaborations: international teams in Madagascar, Europe, and Africa Leadership: Bioinformatics and Genomics Chair (2019–2023) His 2025–2022 publications span evolutionary responses to invasive species, human migration health impacts, chemosensory gene adaptation, and primate genomic diversity. Notable methodological contributions include ancient DNA recovery and comparative paleogenomics. Perry advises graduate students like Vanessa Garcia and Annette Mercedes, with grants including NIH support for Cuban health disparity studies. Scientific leadership includes tenure-line promotions (2023) and NASA Space Grant collaborations.

• Cancer Biology
• Mathematical and Computational Modeling
• Bioinformatics
• +۷ مورد دیگر

Dana Pe'er is a Professor and Chair of the Computational and Systems Biology Program at the Sloan Kettering Institute (SKI) of Memorial Sloan Kettering Cancer Center. She is also an Investigator of the Howard Hughes Medical Institute and holds the Alan and Sandra Gerry Endowed Chair. Dr. Pe'er leads an interdisciplinary research group that combines advanced genomics approaches with machine learning to address fundamental questions in biomedical science, with particular focus on cancer biology, developmental biology, and immunology. Dr. Pe'er earned her PhD from Hebrew University in Jerusalem, Israel. Her academic journey includes a postdoctoral fellowship with George Church at Harvard Medical School. Before joining Memorial Sloan Kettering Cancer Center in 2016, she held faculty positions at Columbia University. Dr. Pe'er's research focuses on understanding cellular plasticity, the consequences of intra-tumor heterogeneity, cancer evolution and metastasis, and the mechanisms by which regulatory circuits go awry in disease. Her lab combines single-cell and spatial profiling technologies with machine learning approaches to investigate gene regulation, cellular plasticity, and cell-cell communication in the contexts of cancer, immunity, and development. They are particularly interested in how organisms develop from a single cell to generate diverse cell types, how epigenetic control rewires during development, and how cells communicate to execute multicellular responses. Analysis of Dr. Pe'er's recent publications reveals a strong focus on developing computational methods for single-cell and spatial genomics data analysis. Her work spans cancer types including pancreatic, prostate, colorectal, and breast cancer, with emphasis on tumor heterogeneity, metastasis mechanisms, and cellular plasticity. A significant portion of her research involves creating novel algorithms and tools like CellRank, REUNION, and SEACells that enable researchers to extract meaningful biological insights from complex genomic datasets. 2023 Class of 2023 Inductee - American Academy of Cancer Research (AACR) Academy 2023 Innovator Award - International Society for Computational Biology (ISCB) 2021 Fellow - International Society for Computational Biology (ISCB) Howard Hughes Medical Institute Investigator (2021) 2019 Ernst W. Bertner Memorial Award - University of Texas MD Anderson Cancer Center 2016 Lenfest Distinguished Faculty Award - Columbia University 2014 Director's Pioneer Award - National Institutes of Health 2014 Overton Prize - International Society for Computational Biology (ISCB) Dr. Pe'er is known for her dedicated mentorship approach, describing herself as "a mama bear" who cares deeply about her trainees while expecting independence, innovation, and hard work. She mentors numerous PhD students and postdocs in her lab. Her HHMI Investigator award provides approximately $9 million over seven years, enabling ambitious research directions. She also collaborates extensively with the Single-cell Analytics and Innovation Lab (SAIL) at MSK to generate new data from emerging technologies, working closely with wet-lab collaborators at MSK and beyond to apply computational methods to cutting-edge datasets across multiple disease areas. The Pe'er Lab is an interdisciplinary group of computational biologists with diverse backgrounds ranging from pure mathematics to clinical medicine. They work closely with wet-lab collaborators to apply their computational methods to cutting-edge datasets across cancer, immunology, and developmental biology. The lab is described as open, supportive, collaborative, and fun, with access to world-class facilities at the Sloan Kettering Institute. Dr. Pe'er's work continues to push the boundaries of computational biology and cancer research, with the ultimate goal of developing more effective, personalized therapies for cancer patients.

Li Tangمشاهده پروفایل

دانشیار

• Immunoengineering
• Cancer Immunotherapy
• Immune Metabolism
• +۷ مورد دیگر

Li Tang is an Associate Professor with tenure at École polytechnique fédérale de Lausanne (EPFL), affiliated with the Institute of Bioengineering (IBI) and the Institute of Materials Science and Engineering (IMX) within the School of Engineering (STI). She leads the Laboratory of Biomaterials for Immunoengineering, focusing on developing innovative strategies at the intersection of immunology, materials science, and cancer therapy. Her work bridges fundamental research and clinical translation, with multiple ongoing clinical trials based on CAR-T cell therapies developed in her lab. B.S. in Chemistry, Peking University (2003–2007) Ph.D. in Materials Science and Engineering, University of Illinois at Urbana-Champaign (2007–2012) Postdoctoral Fellow, MIT (2013–2016) Her research lies at the forefront of immunoengineering, integrating chemical, metabolic, and mechanical approaches to modulate immune responses. Key areas include cancer immunotherapy, immune metabolism, mechano-immunology, and biomaterials. She investigates how physical and biochemical cues can reprogram T cells, overcome exhaustion, and enhance tumor targeting. Her work emphasizes multidimensional immunity-disease interactions, aiming to develop safer and more effective therapies for cancer and autoimmune diseases. The recent publications highlight a strong trend in engineering immune cells (especially CAR-T) for enhanced durability and function, using advanced biomaterials and metabolic reprogramming. There is a clear focus on overcoming challenges in solid tumors, modulating the tumor microenvironment, and translating findings into clinical applications. The use of nanoparticle delivery, single-cell analysis, and biomechanical cues are recurring themes across her work. Notable scientific awards include: Friedrich Miescher Award (2025) ERC Starting Grant (2018) MIT TR35 Innovators Under 35 (China Region, 2020) Nano Research Young Innovator Award (2018) Biomaterials Science Emerging Investigator (2019) Materials Horizons Emerging Investigator (2020) Li Tang actively mentors PhD students across multiple doctoral programs (EDBB, EDMS, EDMX) and has advised numerous graduates who have gone on to prestigious postdoctoral and faculty positions. She is involved in significant research grants, including an Innosuisse project with Novochizol SA, and her lab is supported by competitive funding. She teaches core courses such as Immunoengineering and Next-Generation Biomaterials, shaping the next generation of scientists. Her lab fosters interdisciplinary collaboration and innovation, with active projects in chemical, metabolic, and mechanical immunoengineering, as well as CAR-T cell development. She is the Principal Investigator of the Tang Lab, which includes postdoctoral fellows, PhD students, and technical staff. The lab is actively recruiting and has a strong publication and clinical translation record. Tang Lab is also involved in multiple MA/BA training projects and promotes student engagement in cutting-edge research. The lab’s discoveries are being translated into clinical trials, reflecting a strong commitment to translational science.

• Medical Genetics
• Nephrology
• Genomics
• +۳ مورد دیگر

Dr. Ian Wilson is a researcher at Newcastle University with a focus on medical genetics, nephrology, and genomic analysis. His work spans genetic determinants of kidney diseases, mitochondrial disorders, and biomarker development. Notable contributions include studies on uromodulin genetics in African populations, copy-number variations in rare diseases, and kidney ciliopathies. He has collaborated extensively on projects involving genome sequencing, mitochondrial replacement therapy, and muscular dystrophy biomarkers. Wilson's research integrates computational tools like machine learning for predictive modeling in urolithiasis and employs advanced imaging techniques for disease progression monitoring. Key areas: Genetic epidemiology, renal genomics, mitochondrial DNA analysis Focus on translational applications: Biomarker development for kidney stones and muscular dystrophies Interdisciplinary collaborations in ophthalmology and orthopedics His publications reflect a commitment to advancing diagnostic accuracy and understanding complex genetic disorders through multi-omics approaches.

Wei-Jen Tangمشاهده پروفایل

استاد

• Structural Biology
• Biochemistry
• Molecular Biology
• +۴ مورد دیگر

Wei-Jen Tang is a Professor at the University of Chicago, affiliated with the Ben May Department of Cancer Research. His work integrates structural biology and biochemistry to study protein interactions critical to human health, particularly in Alzheimer's disease, diabetes, and bacterial pathogenesis. Education: B.S. in Zoology, National Taiwan University; Ph.D. in Biological Sciences, University of Texas, Austin; Postdoctoral training in Virology and Pharmacology at University of Texas Southwestern. His research focuses on: Amyloid Peptide-Degrading Proteases: IDE and PreP for Alzheimer's and diabetes. Chemokines: CCL5 and CCL3 in inflammation and HIV. Bacterial Toxins: Edema factor in anthrax and bio-defense. Recent publications highlight structural insights into IDE, PreP, and anthrax toxins, with keywords spanning Structural Biology , Biochemistry , and Therapeutics . Funding includes NIH and American Heart Association grants. Awards include AHA Established Investigator and Cancer Research Foundation Young Investigator. Lab updates note new members and a 2025 publication on PreP.

Kathrin Langمشاهده پروفایل

استاد

• Chemical Biology
• Protein Engineering
• Genetic Code Expansion
• +۳ مورد دیگر

Kathrin Lang is a Full Professor at the Department of Chemistry and Applied Biosciences, ETH Zurich, and Head of the Organic Chemistry Laboratory. Her research focuses on chemical biology, particularly the development of tools for genetic code expansion to incorporate non-canonical amino acids into proteins and advance bioorthogonal chemistries for studying biological processes. Keywords: Genetic Code Expansion, Bioorthogonal Chemistry, Protein Engineering, Ubiquitylation Networks, Post-Translational Modifications. Lang’s work emphasizes proximity-triggered crosslinking reactions, bioorthogonal labeling, and in vivo chemistries to address challenges in protein interaction mapping and structural elucidation. Her group’s recent publications highlight methodologies for dual protein labeling, deciphering ubiquitin code, and enhancing cycloaddition reactivity. Current projects include exploring cyclopropene-fused dibenzocyclooctynes for improved labeling and investigating methylated lysine as a conformational regulator in Hsp90. Funding sources include the ERC (Ubl-tool), DFG (SFB1035, SPP1926), and ETH Zurich. She contributes to education through courses like Genetic Code Expansion for Studying Posttranslational Modifications and Chemical Biology and Synthetic Biochemistry . Collaborative efforts span structural biology, microbiology, and synthetic biochemistry, with applications in ubiquitin research and cellular imaging.

Hector Aguilar-Carrenoمشاهده پروفایل

استاد

• Virology
• Paramyxoviruses
• Viral Entry Mechanisms
• +۷ مورد دیگر

Hector Aguilar-Carreno is a Professor of Virology in the Department of Microbiology and Immunology at Cornell University's College of Veterinary Medicine, where he also serves as Associate Vice Provost in the Office of the Vice President for Research and Innovation. His research focuses on high-mortality paramyxoviruses including Nipah virus (NiV) and Hendra virus (HeV), as well as coronaviruses and other enveloped viruses. Dr. Aguilar-Carreno received his BS in Biochemical Engineering from Instituto Tecnologico de Tepic, Mexico, followed by an MS in Biology from California State University, Los Angeles, and a PhD in Biochemistry and Molecular Biology from the University of Southern California. He completed postdoctoral training in Virology at UCLA under Dr. Benhur Lee before becoming an Assistant Professor at Washington State University's Paul G. Allen School for Global Animal Health. His research spans four main areas: (1) Viral entry mechanisms, where his lab has identified novel domains in viral glycoproteins important for membrane fusion; (2) Viral egress, using multi-omics approaches to study viral assembly and budding; (3) Vaccine development using viral-like particles to generate neutralizing antibodies; and (4) Antiviral discovery targeting enveloped viruses. His lab employs innovative techniques including Flow Virometry and Raman Spectroscopy to study viral entry processes. Analysis of his recent publications reveals a strong focus on paramyxoviruses (particularly Nipah and Hendra viruses), coronavirus research, and the development of broad-spectrum antivirals. His work spans fundamental virology to translational applications, with numerous publications in high-impact journals including Nature, Science, and Cell Reports. President Elect of the American Society of Virology Chair of the American Society of Virology Diversity, Equity, and Inclusion committee Chair of the Cornell CVM Diversity Committee Director of the Cornell Program for Achieving Career Excellence Chair of 16 PhD student thesis committees Dr. Aguilar-Carreno has served on numerous scientific committees including the American Society for Virology Education Committee, the American Society of Microbiology Committee for Minority Education, and as a Standing Member of the VIR-A NIH study section. His leadership extends to chairing the Cornell CVM Diversity Committee and serving on the Cornell presidential postdoctoral fellowship committee, demonstrating significant commitment to diversity and mentorship in science.

Hang Luمشاهده پروفایل

دانشیار

• Science Communication
• Health Communication
• Environmental Communication
• +۴ مورد دیگر

Hang Lu is an Associate Professor in the Department of Communication and Media at the University of Michigan's College of Literature, Science, and the Arts. He specializes in science, health, environmental, and risk communication (ComSHER), with a focus on media psychology. His research explores audience responses to media messages about sensitive topics and strategies to enhance message effectiveness. Lu holds a Ph.D. in Communication from Cornell University (2018), along with advanced degrees from Cornell, Marquette University, and Central South University in China. He directs the Media and Risk (MaR) Lab and previously served as a postdoctoral fellow at the Annenberg Public Policy Center. His research spans four main areas: 1) emotion dynamics in media responses, 2) predictors of information behaviors, 3) media effects on stigmatization, and 4) AI applications in sensitive domains. He has published in journals like Journal of Communication , Risk Analysis , and Public Understanding of Science , earning multiple top paper awards. As Vice Chair of the Environmental Communication Division at the International Communication Association, Lu contributes to interdisciplinary dialogue. His work addresses critical societal issues such as climate change communication, vaccination hesitancy, and emerging technology ethics.

Sabine Dittmannمشاهده پروفایل

استاد

• Coastal Ecosystem Ecology
• Benthic Community Ecology
• Mangrove and Saltmarsh Ecology
• +۴ مورد دیگر

Professor Sabine Dittmann is a leading expert in coastal ecosystem ecology and marine sciences at Flinders University, Australia. As a Professor of Marine Biology in the College of Science and Engineering, her work bridges research and environmental management, focusing on hypersaline estuaries, blue carbon restoration, and invasive species control. She holds a Habilitation in Ecology from the University of Bremen (2001), PhD from the University of Göttingen (1987), and MSc from the same institution (1984). Her research interests include coastal ecosystem health, mangrove and saltmarsh restoration, and decision support frameworks for marine conservation. She has advised government agencies on marine parks, Commonwealth Marine Reserves, and the Coorong ecosystem. Key roles include national president of the Australian Marine Sciences Association (2012–2014), current president of the Royal Society of South Australia, and member of the Australian Antarctic Science Council since 2019. Her recent work emphasizes the global challenges of hypersaline wetland restoration, invasive species impact, and blue carbon methodologies. Over 112 publications span estuarine dynamics, benthic macrofauna, and policy-relevant ecosystem assessments. Projects like the Coorong benthic surveys highlight her commitment to translating science into conservation action.

James Shorterمشاهده پروفایل

استاد

• Protein Folding and Proteostasis
• Neurodegenerative Diseases
• Prion and Amyloid Biology
• +۷ مورد دیگر

James Shorter is a Professor of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania. He is affiliated with multiple prestigious institutes, including the Institute on Aging (IOA), the Institute for Translational Medicine and Therapeutics (ITMAT), the Penn Center for AIDS Research (CFAR), the Chemistry-Biology Interface (CBI), and the Penn Institute for RNA Innovation. He mentors several training programs such as the Penn Summer Undergraduate Internship Program (SUIP), PennPREP, and the Translational Research Immersion Program (TRIP), and serves as a Primary Trainer at the Center for Neurodegenerative Research (CNDR). Ph.D. in Cell Biology, University of London, 2000 M.A. in Biology, University of Oxford, 1995 Dr. Shorter’s research focuses on protein homeostasis, particularly the mechanisms of protein disaggregation and the role of prion-like domains in neurodegenerative diseases such as ALS, Alzheimer’s, Parkinson’s, and frontotemporal lobar degeneration. His lab investigates the Hsp104 disaggregase from yeast and has engineered variants to combat human proteinopathies. They also identified the mammalian disaggregase system (Hsp110/Hsp70/Hsp40) and explore how small molecules and nuclear import receptors can reverse pathological phase transitions of RNA-binding proteins like TDP-43 and FUS. His work bridges structural biology, genetics, and translational neuroscience. His recent publications highlight trends in targeting TDP-43 and FUS proteinopathies, engineering Hsp104 for selective detoxification, understanding mitochondrial disaggregases like Skd3, and modulating phase transitions with nuclear import receptors. His research spans from fundamental mechanisms of protein folding to therapeutic development for neurodegenerative diseases. Faculty Member, Institute on Aging (IOA) Faculty Member, Institute for Translational Medicine and Therapeutics (ITMAT) Mentor, Penn Summer Undergraduate Internship Program (SUIP) Primary Trainer, Center for Neurodegenerative Research (CNDR) Faculty Member, Penn Center for AIDS Research (CFAR) Member, Penn Institute for RNA Innovation Mentor, Translational Research Immersion Program (TRIP) Dr. Shorter advises numerous graduate students and postdoctoral researchers through the Biochemistry and Molecular Biophysics, Pharmacology, Neuroscience, and Cell and Molecular Biology graduate groups. His lab receives funding from NIH and other sources to support research on protein disaggregation, phase separation, and neurodegenerative disease mechanisms. He has trained many scientists now active in academia and biotech. His lab, located in Stellar-Chance Laboratories, operates at the intersection of biochemistry, cell biology, and translational medicine, with active projects on Hsp104 engineering, mitochondrial proteostasis, and the role of RNA-binding proteins in disease. The lab collaborates widely across Penn and with international partners to advance understanding and treatment of protein misfolding disorders.

Silu Wangمشاهده پروفایل

استادیار

• Speciation
• Adaptation
• Forest Evolutionary Genomics
• +۳ مورد دیگر

Dr. Silu Wang is an Assistant Professor in the Department of Biological Sciences at the University at Buffalo. Her research focuses on speciation, adaptation, and forest evolutionary genomics, particularly in avian species. She leads the Forest Speciation Lab, studying the genomic and ecological mechanisms underlying species divergence in North American and global forest ecosystems. Her work integrates field studies, genomic analyses, and computational modeling to address biodiversity conservation challenges under climate change. Education: BS in Behavior Genetics and Neurobiology, University of Toronto MA in Ecology, Evolution and Behavior, University of Texas, Austin PhD in Zoology, University of British Columbia Postdoctoral Research at University of California Berkeley and UC Davis Research Interests: Dr. Wang investigates how hybridization, climate adaptation, and reproductive isolation shape avian biodiversity. Her lab uses old-growth forest bird species as models to study early-stage speciation processes, including mate choice, genetic incompatibilities, and mitochondrial-nuclear interactions. Key themes include understanding organismal responses to environmental changes and developing genomic tools for conservation prioritization. Lab and Teams: The Forest Speciation Lab collaborates with institutions globally, focusing on fieldwork in temperate and tropical forests. Current projects include studies on warbler hybrid zones, tinamou speciation, and the genomic architecture of mitonuclear coevolution. Teaching: Dr. Wang teaches courses on Speciation, Tropical Ecology, and Evolutionary Biology, emphasizing hands-on research training for students.

Kristina Schoonjansمشاهده پروفایل

دانشیار

• Bile acid signaling
• Nutrient sensing
• Intermediary metabolism
• +۱۱ مورد دیگر

Kristina Schoonjans is an Associate Professor at EPFL’s School of Life Sciences, where she leads the Laboratory of Metabolic Signaling (UPSCHOONJANS). Her research focuses on the molecular mechanisms of bile acid signaling, nutrient sensing, and intermediary metabolism, particularly in the context of metabolic disorders such as obesity, fatty liver disease, and cancer. She investigates how the liver-gut-brain axis integrates metabolic signals through nuclear receptors and mitochondrial dynamics. Her research interests include: Bile acid signaling and its role as a hormonal regulator Nutrient and metabolite sensing in energy homeostasis Intermediary metabolism and metabolic disorders Role of nuclear receptors (e.g., TGR5, LRH-1) in liver, gut, and adipose tissue Mitochondrial dynamics and fission in metabolic regulation Organoid models for studying liver and intestinal metabolism Systems genetics using BXD mouse populations The most recent articles highlight a strong focus on bile acid signaling, particularly through TGR5 and LRH-1, in regulating metabolic health. Themes include the conversion of white fat to beige fat (beiging), hepatic tumorigenesis, mitochondrial fission, and the use of organoid and genetically engineered mouse models. There is a consistent emphasis on translational applications for obesity, fatty liver disease, and cancer. Scientific honors include: Windaus Prize from the Dr. Falk Foundation (2010, shared with Johan Auwerx) for the discovery of the signaling/endocrine function of bile acids Prof. Schoonjans actively supervises PhD students and has advised numerous doctoral candidates who have since completed their theses. Her lab is supported by multiple grants from Swiss and international funding agencies, including the Swiss National Science Foundation, EPFL, CONACYT, and the Foundation for Health and Education. She teaches in several doctoral programs at EPFL, including Life Sciences Engineering, and contributes to education through the SSV and EDBB/EDCB/EDMS-ENS programs. The Schoonjans Lab brings together scientists, doctoral assistants, and technicians working on projects related to metabolic signaling. The team uses advanced techniques such as genetically modified mouse models, organoid cultures, and multi-omics (metabolomics, proteomics, transcriptomics) to study the liver-gut and brain-liver axes. The lab has a strong track record of high-impact publications and collaborations with institutions worldwide.

Joshua D. Rabinowitzمشاهده پروفایل

استاد

• Cellular Metabolism
• Metabolomics
• Systems Biology
• +۵ مورد دیگر

Joshua D. Rabinowitz is a Professor of Chemistry and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, where he also serves as Director of the Ludwig Princeton Branch. His research focuses on achieving a quantitative, comprehensive understanding of cellular metabolism, with applications in both basic science and medical research. Dr. Rabinowitz's research interests span multiple areas of metabolism and systems biology: Quantitative analysis of metabolic networks and regulation Metabolomics and measurement of metabolite concentrations and fluxes Cancer cell metabolism and therapeutic targeting Metabolic regulation in microbes (E. coli, Saccharomyces cerevisiae) Biofuel production (focusing on Clostridium acetobutylicum) Metabolic impact of pathogen infection (viral infection of human cells) His laboratory has developed innovative methods for measuring cellular metabolites using state-of-the-art mass spectrometry technology and approaches for quantitating metabolic fluxes through isotope-labeling data interpretation. Analysis of recent publications reveals a strong focus on NAD+ metabolism, cancer metabolism, metabolic adaptations in disease states, and the intersection of metabolism with immunology and neuroscience, particularly in areas like T cell metabolism, Alzheimer's disease, and cardiac function. Dr. Rabinowitz has received recognition as a Highly Cited Researcher by Web of Science, indicating significant impact in his field. He advises several graduate students and has mentored numerous alumni, including Michel I. Nofal, Edmundo Leiva III, and Sean Hackett. His research is supported by multiple programs including NIH NHGRI Training Program and QCB Graduate Program. The Rabinowitz Lab operates at the intersection of chemistry, biology, and computational science, with all projects involving a mix of biological experiments, metabolomics, and computation to achieve their goal of a holistic understanding of cellular metabolism.