جستجوی استاد راهنمای دانشگاهی

Tim Lewensمشاهده پروفایل

استاد

• Philosophy of Biology
• Philosophy of Science
• Bioethics
• +۳ مورد دیگر

Tim Lewens is Professor of Philosophy of Science and Head of the Department of History and Philosophy of Science at the University of Cambridge, currently on leave for the 2024/25 academic year. His career bridges philosophy, biology, and bioethics with significant institutional roles including Deputy Director of CRASSH (2014-2017) and Council Member of the Nuffield Council on Bioethics (2009-2015). His research focuses on philosophy of biology, evolutionary theory, and bioethics, with particular expertise in human nature debates, extended evolutionary synthesis, and medical ethics. Key contributions include critical analyses of mitochondrial replacement therapy ethics, genome editing implications, and conceptual challenges in cultural evolution. His work consistently addresses interdisciplinary tensions between biological determinism and social constructivism. Analysis of his 15 most recent publications reveals dominant themes in evolutionary philosophy (40%), bioethics (35%), and conceptual foundations of science (25%). Notable trends include re-examining Paleyan design arguments in modern biology, ethical frameworks for emerging biotechnologies, and interdisciplinary approaches to human nature that challenge essentialist perspectives. Lewens has secured major research funding including an ERC grant for 'A Science of Human Nature?' (2011-2016) and Templeton Foundation funding for 'Putting the Extended Evolutionary Synthesis to the Test' (2016-2019). His policy impact is evident through contributions to Nuffield Council reports on mitochondrial DNA disorders (2012) and human body donation (2011), demonstrating applied philosophical engagement with contemporary medical ethics.

Irina A. Anselmمشاهده پروفایل

استادیار

• Genetics
• Neurology
• Metabolic Disorders
• +۵ مورد دیگر

Irina A. Anselm, MD is Assistant Professor of Neurology at Harvard Medical School and Director of the Mitochondrial Program at Boston Children's Hospital. She co-directs the Neurometabolic Program and serves as clinical expert for the hospital's Precision Medicine Service. Her work spans pediatric neurology , neurogenetics , and mitochondrial medicine . Medical School: St. Petersburg Pediatric Medical Academy (1984) Residency: University of Massachusetts Medical Center (1995) Fellowship: New England Medical Center (1998) Dr. Anselm specializes in mitochondrial disorders and neurometabolic syndromes affecting children. Her research focuses on genetic diagnosis , experimental therapies , and clinical management of these complex conditions. She leads clinical trials evaluating novel treatments like dichloroacetate (DCA) for lactic acidemia and collaborates with biotech companies on gene therapy approaches. Key publication areas include mitochondrial disease pathophysiology , neurodevelopmental genetic mutations , and experimental treatment outcomes . She has authored consensus guidelines for mitochondrial disease management and serves as reviewer for multiple journals including Journal of Pediatric Neurology and Current Pediatric Reviews .

Torsten Ochsenreiterمشاهده پروفایل

استاد

• Molecular Parasitology
• Mitochondrial Biogenesis
• Protozoan Parasites
• +۵ مورد دیگر

Prof. Torsten Ochsenreiter is a Group Leader at the Institute of Cell Biology, University of Bern, and part of the Multidisciplinary Center for Infectious Diseases (MCID). His research focuses on molecular parasitology, particularly on trypanosomes and malaria parasites, utilizing advanced microscopy techniques to study fundamental biological processes. His primary research interests include mitochondrial biogenesis, kinetoplast genome maintenance, RNA editing mechanisms, and cytoskeletal dynamics in Trypanosoma brucei . He investigates how mitochondrial DNA is segregated during cell division and how post-translational modifications regulate parasite transmission. His work bridges cell biology, structural biology, and infectious disease research to understand pathogenic mechanisms in neglected tropical diseases. Analysis of his recent publications reveals a consistent focus on the tripartite attachment complex (TAC), mitochondrial genome inheritance, and expansion microscopy applications. His research demonstrates how structural adaptations in parasite organelles enable survival and transmission, with significant implications for developing novel therapeutic strategies against African sleeping sickness and malaria. No scientific awards were mentioned in the provided text. Prof. Ochsenreiter advises students and leads an active research team at the University of Bern. The Ochsenreiter lab provides opportunities for undergraduate and graduate students to engage in cutting-edge parasitology research, though specific grant funding details were not provided in the text. The Ochsenreiter lab operates within the Institute of Cell Biology and specializes in molecular parasitology techniques including expansion microscopy, cryo-electron tomography, and genetic manipulation of trypanosomes. The team investigates mitochondrial biology and cytoskeletal organization to uncover vulnerabilities in parasite life cycles.

Derek J. Taylorمشاهده پروفایل

استاد

• Evolutionary Biology
• Molecular Evolution
• Genetics
• +۴ مورد دیگر

Derek J. Taylor is a Professor in the Department of Biological Sciences at the University at Buffalo (College of Arts and Sciences), specializing in evolutionary biology and molecular evolution. His research focuses on the evolutionary genetics of aquatic invertebrates, particularly cladocerans (e.g., Daphnia species), and integrates molecular, genomic, and phylogenetic approaches to study speciation, hybridization, species introductions, and paleovirology. He leads the Taylor Lab, which explores topics such as viral evolution in insects and microbats, and the evolutionary history of freshwater crustaceans. Education: PhD in Biology from the University of Guelph, followed by postdoctoral research at the University of Michigan. Research Interests: Molecular evolution of species complexes, host-virus coevolution, phylogeography, and the evolutionary maintenance of viral genes in host genomes. His work bridges genetics, ecology, and systematics to address questions in evolutionary biology. Key contributions include studies on filovirus evolution in bats, the phylogenetics of Daphnia species, and the origins of biodiversity in Holarctic freshwater ecosystems. His lab’s findings have been published in journals like Zoological Journal of the Linnean Society , Virus Evolution , and Ecography . Contact: Hochstetter Hall H530, Buffalo, NY | Office Hours: Thursdays 2:00–4:00 PM.

• Neurology
• Neuromuscular Diseases
• Inherited Neuropathies
• +۶ مورد دیگر

Professor Mary M. Reilly is a distinguished academic and clinician serving as Professor of Neurology in the Department of Neuromuscular Diseases at University College London's Queen Square Institute of Neurology. She is also a consultant neurologist at the National Hospital for Neurology and Neurosurgery, Queen Square, London. Her academic appointments include: Professor of Neurology, University College London, Department of Neuromuscular Diseases Head of the Division of Clinical Neurology, UCL Queen Square Institute of Neurology Lead of the peripheral nerve clinical and research group Professor Reilly's research focuses on inherited neuropathies, with particular emphasis on Charcot-Marie-Tooth disease (CMT) and hereditary transthyretin amyloidosis (hTTRA). Her work spans the entire translational pipeline, from gene identification and pathogenetic studies through natural history studies and outcome measure development to clinical trials. She approaches her research with a patient-centered perspective, with questions arising directly from clinical encounters. Her extensive publication record demonstrates consistent contributions to understanding various forms of Charcot-Marie-Tooth disease, amyloid neuropathies, and other inherited peripheral nerve disorders. Her research employs diverse methodologies including genomic analysis, biomarker development, imaging techniques, and international collaborative studies to advance understanding and treatment of these conditions. Professor Reilly has received significant recognition for her work: Elected Fellow of the Academy of Medical Sciences (2020) Awarded Fellow of the European Academy of Neurology (2023) Past President of the Association of British Neurologists (ABN) Past President of the British Peripheral Nerve Society (BPNS) Past President of the international Peripheral Nerve Society (PNS) Current chair of the Guarantors of Brain Professor Reilly has made substantial contributions to education and mentorship in the field. As Director of Training in the inherited neuropathy consortium (INC), she developed and runs an international inherited neuropathy fellowship scheme since 2009, with 14 fellows completed. She established and directed an international fellowship program through the International Centre for Genomic Medicine in Neuromuscular Diseases (ICGNDM) between 2019-2024, connecting institutions across UK, Brazil, India, South Africa, Zambia and Turkey. She also successfully ran the MRC Neuromuscular PhD programme between 2008 and 2018, mentoring 39 students. She leads the MRC Centre for Neuromuscular Diseases Biobank London, which plays a crucial role in advancing research on rare and neuromuscular diseases through the collection and analysis of biological samples.

• Entomology
• Molecular Biology & Genetics
• Genetics & Heredity
• +۵ مورد دیگر

Cengiz İkten is an Associate Professor at Akdeniz University , Faculty of Agriculture, Department of Plant Protection. He holds a PhD in Entomology from the University of Nebraska-Lincoln (2002) and has been with Akdeniz University since 2003, rising from Research Assistant to Associate Professor in 2020. Education : PhD: University of Nebraska-Lincoln (Entomology) MSc: University of Nebraska-Lincoln (Ianr) BSc: Ankara University (Plant Protection) Research Focus spans entomology, molecular genetics, plant protection, and agricultural biotechnology. His work addresses insecticide resistance in pests like whiteflies and thrips, develops molecular markers for crop resistance (chickpea, sesame), and explores genetic relationships in legume species. Recent Publications highlight his expertise in molecular diagnostics (AFLP, SSR, qPCR), phytoplasma resistance in sesame, and pest management strategies for chickpea and sorghum. He collaborates on genetic linkage mapping and transgressive segregation studies. Projects include TUBITAK-funded research on cowpea seed bug resistance (2009-2012) and EU-grant studies on genetic markers for Fusarium resistance. He serves as Deputy Head of Department and Erasmus Coordinator.

Christoph J. Fahrniمشاهده پروفایل

استاد

• Bioinorganic Chemistry
• Fluorescent Probes
• Metal Ion Homeostasis
• +۴ مورد دیگر

Christoph J. Fahrni is a Professor at the School of Chemistry and Biochemistry, Georgia Institute of Technology. He earned his M.S. from the Federal Institute of Technology (ETH) in Zurich and a Ph.D. in Chemistry from the University of Basel in 1995. After postdoctoral work at Northwestern University, he joined Georgia Tech in 1999, where his research focuses on metal ion biochemistry, particularly copper and zinc, using fluorescent probes and X-ray fluorescence imaging. Education: M.S., Federal Institute of Technology (ETH), Zurich Ph.D., University of Basel, 1995 His research integrates synthetic fluorescent probes and X-ray fluorescence microscopy to study intracellular metal ion dynamics, including copper trafficking, zinc homeostasis, and their roles in diseases like Menkes syndrome. The lab develops high-affinity ligands for copper buffering, investigates P-type ATPase transporters, and uses 3D X-ray tomography to map metals in zebrafish embryos. Key methodologies include ratiometric two-photon microscopy and bioorganometallic catalyst design. Recent publications highlight advancements in subzeptomolar copper probes, dynamic zinc imaging during development, and metal chelation therapy applications. Collaborative projects with Prof. Robert Dickson explore low-background fluorescent protein imaging. The Fahrni group trains graduate students like Daisy Bourassa and Adam McCallum, focusing on biochemical copper/zinc interactions and probe development.

Ralph G. Meyerمشاهده پروفایل

استاد

• Molecular Cell Biology
• Reproductive Toxicology
• Developmental Biology
• +۵ مورد دیگر

Ralph G. Meyer is a Professor and Department Head at the College of Veterinary Medicine , Utah State University (USU). He holds a PhD in Molecular Cell Biology (University of Kaiserslautern, 1998) and completed postdoctoral training in Molecular Toxicology at University of Tuebingen and University of Arizona. Education : PhD (1998), MS (1994) in Molecular Cell Biology Academic Roles : Faculty at University of Pennsylvania, Interim Head at USU CVM’s VCLS department Research Interests focus on: Reproductive toxicology and developmental biology Epigenetic regulation of sperm chromatin NAD+ metabolism in aging and disease Scientific Awards : Biology of Reproduction Top Reviewing Editor (2017, 2018) NIH Ruth-Kirschstein-NRSA Fellowship (T32, 2002-2004) Edward A. Smuckler Memorial AACR Poster Award (2004) Teaching : Course director for Fundamentals of Pharmacology (VM7522) and Veterinary Toxicology (VM7523) since 2013. Mentored graduate students including Renata Hoskova and Chelsea Ketchum.

William Newmanمشاهده پروفایل

استاد بالینی

• Pharmacogenetics
• Rare Inherited Conditions
• Genomics
• +۳ مورد دیگر

William Newman is a Clinical Professor of Translational Genomic Medicine at the University of Manchester and Honorary Consultant at Manchester University NHS Foundation Trust. He serves as President of the European Society of Human Genetics (2024-25) and Clinical Director of the NW Genomic Medicine Service Alliance. His roles include co-leading the BRC Theme on Rare Conditions and leading the NHSE Network of Excellence in Pharmacogenetics and Medicines Optimisation. Education: BSc (hons) Experimental Immunology and Oncology MB ChB (hons) from the University of Manchester PhD in genetics from the Wellcome Trust Cell Matrix Centre MA in Healthcare Ethics and Law Research Interests: Rare Conditions : Discovery of genetic causes using next-generation sequencing, focusing on Perrault syndrome, lower urinary tract disorders, and infection-triggered neuropathies. Pharmacogenetics : Clinical implementation of genetic testing to optimize medication responses, including the PALOH study for gentamicin-induced hearing loss prevention. Lower Urinary Tract Malformations : Studies on HPSE2 and LRIG2 genes in urofacial syndrome and bladder exstrophy, supported by the MRC-NIHR Rare Disease Node (REOLUT). Genetics of Perrault Syndrome : Identification of CLPP, MRPL49, PRORP, and DAP3 genes, exploring mitochondrial dysfunction mechanisms. Spliceosomal Disorders : Investigating craniofacial syndromes like Burn McKeown syndrome using mouse and stem cell models. Key Awards: New Statesman Healthcare Positive Impact Award 2022 Times Higher Education (THE) Research Project of the Year: STEM Award 2024 Teaching and Collaborations: Established MSc in Genomic Medicine and PGCert in Clinical Genetics with international partners. Collaborates with institutions like Newcastle University, UCL, and Cambridge on rare disease projects. Leadership in European Society of Human Genetics training programs for cardiac genetics professionals. Labs and Platforms: Manchester Centre for Genomic Medicine, Manchester Regenerative Medicine Network, and the Lydia Becker Institute.

• Genetic Disorders
• Human Infertility
• Embryonic Development
• +۳ مورد دیگر

Odelya Hartung Kaufman, MD, PhD, is a Clinical Geneticist and Associate Research Scientist in the Department of Genetics at Yale School of Medicine. She specializes in diagnosing and managing genetic conditions in children and adults, with expertise in developmental disabilities, inherited eye disorders, hearing loss, and congenital birth defects. Her research focuses on genetic mechanisms underlying early embryonic defects, human infertility (e.g., unexplained female infertility and recurrent pregnancy loss), and rare undiagnosed diseases via the Undiagnosed Disease Network. Education & Training: MD and PhD in Biomedical Sciences from Albert Einstein College of Medicine (2016) Pediatrics and Medical Genetics Residency at Mount Sinai Hospital (2020) Research Interests: Dr. Kaufman’s work combines clinical practice with research into genetic causes of rare diseases. Her studies utilize zebrafish models to investigate RNA binding proteins’ roles in ovary development and Balbiani body architecture. Recent publications highlight advancements in understanding nutrient sensing pathways and genetic mutations linked to syndromes like Shwachman–Diamond syndrome. Awards & Grants: No specific awards listed, though her work aligns with NIH-funded initiatives through the Undiagnosed Disease Network. Grants and funding sources are not detailed in the provided text. Labs & Teams: Member of the Jiang Lab at Yale School of Medicine, collaborating on interdisciplinary projects at the intersection of genetics and clinical care.

Nicole Tillquistمشاهده پروفایل

پژوهشگر

• Ruminant Nutrition
• Maternal Nutrition Effects
• Fetal Development
• +۳ مورد دیگر

Nicole Tillquist is a Postdoctoral Research Associate at the University of Connecticut in the Department of Animal Sciences. She earned her BS (2018), MS (2020), and PhD (2023) in Animal Sciences from Colorado State University and the University of Connecticut, respectively. She works in Dr. Kristen Govoni’s lab, focusing on the impacts of maternal nutrition on fetal development and offspring health in ruminant species. Education: PhD in Animal Sciences, University of Connecticut (2023) MS in Animal Sciences, Colorado State University (2020) BS in Animal Sciences, Colorado State University (2018) Her research spans nutrient restriction effects on fetal small intestine development, mineral metabolism in ruminants, and how poor maternal diet impacts offspring growth, feed efficiency, and organ function. She investigates these mechanisms using sheep models to identify pathways like hormonal dysregulation, oxidative stress, and epigenetic modifications. Her recent work includes multigenerational studies on mitochondrial function and transgenerational effects of maternal nutrition on offspring immune status, glucose tolerance, and microbiome dynamics. She has presented award-winning talks on metabolic programming in sheep and antioxidant interventions in equine health. Scientific Awards: Awardee Talk: Poor Maternal Nutrition Impacts Metabolic Factors and Glucose Tolerance in Sheep Offspring (2022) Awardee Talk: Astaxanthin Supplementation Reduces Oxidative Stress in Polo Ponies (2022) Her work in Dr. Govoni’s lab integrates ruminant nutrition with developmental biology to address how maternal dietary choices program lifelong health in livestock species.

Coleen T. Murphyمشاهده پروفایل

استاد

• Aging
• Molecular Biology
• Genetics & Genomics
• +۷ مورد دیگر

Coleen T. Murphy is the James A. Elkins Jr. Professor in the Life Sciences and Professor of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics at Princeton University. She serves as Director of the Lewis-Sigler Institute and Director of the Paul F. Glenn Laboratories for Aging Research, highlighting her leadership in aging and genomics research. Her work bridges molecular biology, genetics, and computational approaches to understand aging and age-related decline. Her research focuses on the molecular mechanisms of aging, particularly using the nematode C. elegans as a model organism. Key interests include longevity pathways, insulin/IGF-1 signaling, reproductive aging, neurodegenerative diseases, transgenerational inheritance, and mitochondrial function. Her lab integrates genomic, transcriptomic, and functional screening techniques to identify genes and pathways that regulate aging and healthspan. The recent publications of her lab demonstrate a strong trend in interdisciplinary research combining genetics, neuroscience, and computational biology. Themes include cognitive aging, learned behavior, pathogen avoidance, metabolic regulation, and drug discovery in neurodegenerative models. Her work increasingly employs high-throughput methods and cross-omics analysis to uncover conserved mechanisms relevant to human health. HHMI Faculty Scholar, Howard Hughes Medical Institute (2016) Pioneer Award, National Institutes of Health (2015) Innovation Award, Department of Molecular Biology, Princeton University (2014) Glenn Foundation for Medical Research Award (2012) Dr. Murphy leads a vibrant research group and mentors numerous students and postdoctoral researchers. Her lab has secured significant funding from HHMI, NIH, and the Glenn Foundation, supporting innovative projects in aging and longevity. She also directs major research initiatives, including the Simons Foundation’s SCPAB (Plasticity and the Aging Brain), underscoring her national leadership. The Murphy Lab at Princeton is a multidisciplinary team employing C. elegans to study aging, cognitive decline, and intergenerational signaling. The lab utilizes cutting-edge tools including microfluidics (e.g., CeLab), transcriptomics, and behavioral assays. It is part of the Department of Molecular Biology and the Lewis-Sigler Institute, fostering collaboration across genomics, neuroscience, and computational biology.

Devin Oglesbeeمشاهده پروفایل

استاد

• Molecular Genetics
• Biochemical Genetics
• Mitochondrial Diseases
• +۵ مورد دیگر

Dr. Devin Oglesbee is a Professor and current Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic College of Medicine in Rochester, Minnesota. He serves as Clinical Competency Committee Chair for the Division of Laboratory Genetics and Genomics and maintains active roles in multiple professional organizations including the American College of Medical Genetics and Genomics. PhD in Molecular Biology from University of Oregon (2004) BS with Distinction from University of Oregon (1997) Post-Baccalaureate Program at Universite Lumiere, Lyon (1999) Residency and Fellowship training at Mayo Clinic in Clinical Molecular Genetics and Clinical Biochemical Genetics (2006-2007) Dr. Oglesbee's research focuses on molecular and biochemical genetics with particular emphasis on mitochondrial diseases, inborn errors of metabolism, and newborn screening methodologies. His work bridges laboratory medicine and clinical practice, developing innovative diagnostic approaches for rare genetic disorders. He has pioneered techniques in metabolomics, mass spectrometry-based diagnostics, and biomarker discovery for mitochondrial disorders. His publication record demonstrates consistent contributions to understanding genetic mechanisms of neurodevelopmental disorders, lysosomal storage diseases, and metabolic conditions. Recent work shows increasing focus on multi-omics integration, telehealth applications in rare disease diagnosis, and development of novel diagnostic methodologies for challenging genetic conditions. His research often involves collaboration through the Undiagnosed Diseases Network, highlighting his role in solving complex diagnostic cases. Excellence Through Teamwork Award from Mayo Clinic (2022) Multiple Travel Awards from Society of Inherited Metabolic Disease (2005-2006) William Sistrom Family Bioenergetics Scholarship from University of Oregon (2003) Molecular Biology Training Grant from National Institutes of Health (2000) As Department Chair, Dr. Oglesbee oversees laboratory operations while continuing active research in genetic diagnostics. His work has significantly influenced newborn screening protocols and diagnostic algorithms for metabolic disorders. He serves on numerous committees including the Clinical Laboratory Standards Institute Document Development Committee and as an Ad Hoc Reviewer for the College of American Pathologists, demonstrating leadership in establishing standards for laboratory medicine. Dr. Oglesbee is actively involved with the Mayo Clinic's Undiagnosed Diseases Network site, contributing to the diagnosis of rare genetic conditions through advanced genomic and metabolomic approaches. His laboratory focuses on developing and implementing novel diagnostic methodologies for mitochondrial disorders and inborn errors of metabolism, with particular expertise in mass spectrometry-based techniques.

Reena Karthaمشاهده پروفایل

دانشیار

• Rare Diseases
• Pharmacology
• Oxidative Stress
• +۵ مورد دیگر

Dr. Reena Kartha is an Associate Professor in the Department of Experimental and Clinical Pharmacology at the University of Minnesota College of Pharmacy, where she also serves as the Associate Director of Translational Pharmacology. Her research focuses on rare diseases, particularly investigating the pathophysiological role of oxidative stress and inflammation in rare disorders occurring due to inherited errors of metabolism. Dr. Kartha directs the Center for Orphan Drug Research and leads multiple translational research projects with pharmaceutical industry partners including Sanofi, Takeda, and Pfizer. Dr. Kartha's educational background includes: Molecular and Cellular Biology from Indian Institute of Science, Bangalore, India Biotechnology from Tamil Nadu Agricultural University, India Agriculture from Kerala Agricultural University, India Dr. Kartha's research program is dedicated to deciphering the pathophysiological role of oxidative stress and inflammation in rare disorders, particularly those caused by inherited metabolic errors. Her laboratory conducts studies to elucidate the mechanism of action of drugs using cellular and animal models, with the long-term goal of developing new therapies or optimizing existing treatments for rare diseases. A significant focus of her work involves the identification of novel protein- or miRNA-based biomarkers for early diagnosis, prognosis, and treatment response using patient-derived samples. Her expertise spans molecular pharmacology, biomarker analysis, and rare inherited metabolic disorders, particularly Gaucher disease and adrenoleukodystrophy. Analysis of Dr. Kartha's recent publications reveals a strong focus on rare diseases, particularly Gaucher disease and related lysosomal storage disorders. Her work consistently explores the role of oxidative stress and inflammation in these conditions, and investigates potential therapeutic interventions such as N-acetylcysteine. There is a clear progression from basic mechanistic studies to clinical applications, with an increasing emphasis on biomarker discovery and validation. Her research demonstrates significant collaboration with clinical teams and pharmaceutical industry partners, reflecting the translational nature of her work. Dr. Kartha has received numerous awards and recognitions for her contributions to research and mentorship: CTSI Outstanding Junior Mentor of the Year (2017) NIH Rare Disease Clinical Research Network (RDCRN) Certificate Training Scholar (2016-17) Lysosomal Disease Network Clinical Fellow (2016-18) Senior Research Fellowship from Council for Scientific and Industrial Research, New Delhi, India M.S. Swaminathan award for best scholar in Biotechnology, Coimbatore, India Merit scholarship from Department of Biotechnology, New Delhi, India Dr. Kartha is actively involved in mentoring students and junior researchers, as evidenced by her CTSI Outstanding Junior Mentor award. She leads multiple significant research projects funded by pharmaceutical companies including Sanofi, Takeda, and Pfizer, with a focus on translational pharmacology for rare diseases. Her current projects include investigating extracellular vesicles as potential biomarkers and therapeutic targets in Gaucher disease, and exploring the use of antioxidant or anti-inflammatory medications to mitigate oxidative stress in Type 1 Gaucher Disease. Dr. Kartha directs research activities at the Center for Orphan Drug Research within the Department of Experimental and Clinical Pharmacology. Her laboratory collaborates with multiple research teams across the University of Minnesota and with external partners in the pharmaceutical industry. Her work frequently involves interdisciplinary teams including pharmacologists, biochemists, clinicians specializing in rare diseases, and bioinformaticians for biomarker analysis.

Wendy Robinsonمشاهده پروفایل

استاد

• Medical Genetics
• Epigenetics
• Fetal Development
• +۴ مورد دیگر

Wendy P. Robinson is a Professor in the Department of Medical Genetics at the University of British Columbia Faculty of Medicine , and a Senior Scientist at the BC Children’s Hospital Research Institute . She holds the CIHR Sex and Gender Science Chair . Research Interests: Genetics and epigenetics of early human development, placental function in pregnancy complications (fetal growth restriction, preterm birth), DNA methylation, non-coding RNA, sex differences, and polymorphisms. Her lab employs genomic and bioinformatic tools to study placental health and its impact on newborn outcomes. Recent Publications (2025-2024) focus on X-chromosome inactivation patterns in placenta, cell-type specific DNA methylation, maternal socioeconomic effects on placental epigenetics, and modeling placental development with organoids. Key themes include sex-specific epigenetic regulation , maternal-fetal interactions , and human placental methylome . Awards: UBC Faculty of Medicine Distinguished Achievement Award (2018), with trainees receiving the James Miller Memorial Prize and Mary-Jane Carroll Trainee Award. Students & Collaborations: Supervised PhD/MSc students include Li Qing Wang, Icíar Fernández Boyano, Giulia Del Gobbo, Victor Yuan, and Magda Price. Collaborators span the Alex Beristain Lab and University of Toronto institutions. Laboratory Activities: Regular team-building events like mountain hikes, climbing outings, and kayaking trips, alongside providing open access to epigenetic tools (e.g., Bisearch, SeqDoc) for the research community.