Devin Oglesbee

Dr. Devin Oglesbee is a Professor and current Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic College of Medicine in Rochester, Minnesota. He serves as Clinical Competency Committee Chair for the Division of Laboratory Genetics and Genomics and maintains active roles in multiple professional organizations including the American College of Medical Genetics and Genomics.

• PhD in Molecular Biology from University of Oregon (2004)
• BS with Distinction from University of Oregon (1997)
• Post-Baccalaureate Program at Universite Lumiere, Lyon (1999)
• Residency and Fellowship training at Mayo Clinic in Clinical Molecular Genetics and Clinical Biochemical Genetics (2006-2007)

Dr. Oglesbee's research focuses on molecular and biochemical genetics with particular emphasis on mitochondrial diseases, inborn errors of metabolism, and newborn screening methodologies. His work bridges laboratory medicine and clinical practice, developing innovative diagnostic approaches for rare genetic disorders. He has pioneered techniques in metabolomics, mass spectrometry-based diagnostics, and biomarker discovery for mitochondrial disorders.

His publication record demonstrates consistent contributions to understanding genetic mechanisms of neurodevelopmental disorders, lysosomal storage diseases, and metabolic conditions. Recent work shows increasing focus on multi-omics integration, telehealth applications in rare disease diagnosis, and development of novel diagnostic methodologies for challenging genetic conditions. His research often involves collaboration through the Undiagnosed Diseases Network, highlighting his role in solving complex diagnostic cases.

• Excellence Through Teamwork Award from Mayo Clinic (2022)
• Multiple Travel Awards from Society of Inherited Metabolic Disease (2005-2006)
• William Sistrom Family Bioenergetics Scholarship from University of Oregon (2003)
• Molecular Biology Training Grant from National Institutes of Health (2000)

As Department Chair, Dr. Oglesbee oversees laboratory operations while continuing active research in genetic diagnostics. His work has significantly influenced newborn screening protocols and diagnostic algorithms for metabolic disorders. He serves on numerous committees including the Clinical Laboratory Standards Institute Document Development Committee and as an Ad Hoc Reviewer for the College of American Pathologists, demonstrating leadership in establishing standards for laboratory medicine.

Dr. Oglesbee is actively involved with the Mayo Clinic's Undiagnosed Diseases Network site, contributing to the diagnosis of rare genetic conditions through advanced genomic and metabolomic approaches. His laboratory focuses on developing and implementing novel diagnostic methodologies for mitochondrial disorders and inborn errors of metabolism, with particular expertise in mass spectrometry-based techniques.