Mikael Thollesson is a Senior Lecturer at Uppsala University, affiliated with the Department of Organismal Biology; Systematic Biology and Klubban’s Biological Station. His research focuses on evolutionary biology, phylogenetics, taxonomy, and molecular biology, particularly in marine and freshwater sponges (Porifera), bacterial pathogens, and computational methods in evolutionary analysis. Evolutionary Biology Marine Biology Taxonomy His recent publications highlight trends in sponge biodiversity, phylogeography, bacterial horizontal gene transfer, and mitochondrial gene evolution. Key articles include studies on Swedish demosponge faunas, Silene sect. Arenosae systematics, and computational tools like SPRIT for detecting gene transfers. No explicit awards or grants are mentioned.
Dr. Steven G. Clarke is a Distinguished Professor at UCLA Department of Chemistry & Biochemistry and director of research at the Molecular Biology Institute . His work bridges protein chemistry , methylation biology , and aging research through studies of spontaneous protein damage and its repair mechanisms. Education: BA in Chemistry and Zoology, Pomona College (magna cum laude, Phi Beta Kappa) PhD in Biochemistry and Molecular Biology, Harvard University (NSF Fellow) Postdoctoral Fellowship at UC Berkeley (Miller Fellow) Dr. Clarke's research focuses on protein isoaspartyl repair via PCMT1/PIMT enzymes , ribosomal protein methylation in Saccharomyces cerevisiae , and PRMT family characterization including PRMT7 and PRMT9. His lab combines biochemical assays , genetic models , and structural analysis to investigate aging mechanisms and disease implications. Recent publications highlight: COQ5 structure-function analysis in coenzyme Q biosynthesis PCMTD1 ubiquitin ligase interactions PRMT7 substrate specificity in histone H2B Protein isoaspartyl impacts on T cell function in lupus Novel PRMT inhibitors for cancer therapy Methionine addiction in osteosarcoma malignancy Major scientific awards: American Chemical Society Ralph F. Hirschmann Award in Peptide Chemistry NIH MERIT Award Ellison Medical Foundation Senior Scholar Award William C. Rose Award, ASBMB UCLA Distinguished Teaching Award (Eby Award winner) Current lab members include PhD candidates Eric Pang (UCSB) and Sining "Cindy" Wang (UCLA), while undergraduates Celeste Medina-Seymoure , Elizabeth Oroudjeva , Olivia Pacheco , and Jasmine Winter contribute to ongoing proteostasis studies. Collaborations with Profs. Jose Rodriguez and Catherine Clarke demonstrate interdisciplinary research approaches.
Michele Klingbeil is a Professor in the Department of Microbiology at the University of Massachusetts Amherst, where she leads the Klingbeil DNA Replication Laboratory. She received her PhD in Cell and Molecular Biology from the University of Toledo in 1996 and previously worked at Johns Hopkins School of Medicine before moving to UMass in July 2007. Her educational background includes: PhD in Cell and Molecular Biology, University of Toledo, 1996 Dr. Klingbeil's research focuses on the unique biology of trypanosomatid parasites, particularly Trypanosoma brucei , the causative agent of African sleeping sickness. Her laboratory investigates two main areas: (1) replication of the unusual mitochondrial DNA network called kinetoplast DNA (kDNA), and (2) nuclear DNA replication initiation. Her work on kDNA is particularly significant as this structure is essential for parasite survival but has no counterpart in mammalian hosts, making it an attractive drug target. She employs a combination of reverse genetics (RNAi), cell biology, and biochemistry to understand the replication and repair mechanisms of kDNA, with a special focus on a family of four DNA polymerases related to bacterial Pol I. Dr. Klingbeil's recent publications reveal her laboratory's deep investigation into mitochondrial DNA polymerases in trypanosomatids, with discoveries showing multiple polymerases having specialized functions in kDNA replication and repair. Her research has established that several of these polymerases are essential for parasite viability, opening new avenues for drug development. She has also made significant contributions to understanding the simplified Origin Recognition Complex in trypanosomatids compared to other eukaryotes. Dr. Klingbeil has received the Thomas G. Lessie Distinguished Lectureship Award for her impact on teaching at the graduate level. Her research is funded by the National Institutes of Health, U.S. Department of Agriculture, the Joeph P. Healey Endowment, and the University of Massachusetts Amherst. She has mentored numerous graduate and undergraduate students, including current PhD candidates Dave Bruhn, Jeniffer Concepción, and Juemin Luo, as well as visiting scholar Eva Vidal Rico. Her former students have gone on to positions at institutions including Dana Farber/Broad Institute, Regis College, and Flagship Ventures. The laboratory regularly participates in scientific conferences including the Molecular Parasitology Meeting at Woods Hole and the Kinetoplastid Molecular Cell Biology conference. Dr. Klingbeil teaches several courses including Parasitology (MICRO 590S), Parasitology Lab (MICRO 590L), Molecular Mechanisms of Pathogenesis (MICRO 797P), Advanced Cell Biology (MCB 641), and Writing in Microbiology (MICRO 360). Her laboratory organizes regular social events including pumpkin carving parties and outings to Six Flags New England and Mt. Sugarloaf.
Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788
Jennifer L. Clarke is a Professor in the Department of Statistics at the University of Nebraska–Lincoln and Director of the Quantitative Life Science Initiative. She holds leadership roles in enabling big data integration across the University of Nebraska system through collaborative research programs. Her affiliations include the Institute of Agriculture and Natural Resources (IANR) and the College of Agriculture and Natural Resources. Dr. Clarke's research focuses on statistical methodology for high-dimensional data, computational biology, bioinformatics, and bacterial genomics. Her work bridges statistical innovation with applications in oncology, microbiome analysis, and agricultural phenomics. Key areas include predictive modeling, machine learning, and genomic/metagenomic data integration. Her recent publications span cancer biomarker discovery, plant phenotyping methodologies, and microbial community analysis, reflecting her interdisciplinary approach. Articles emphasize translational applications like therapeutic target identification and precision agriculture. Dr. Clarke leads initiatives fostering collaboration between statisticians and domain scientists, including the Quantitative Life Science Initiative and contributions to the Agricultural Genome-to-Phenome Initiative (AG2PI). Her work advances data-driven solutions for healthcare and food security challenges. Notable projects include developing statistical tools for microbiome studies, analyzing root architecture via 3D imaging, and investigating cranberry-derived compounds' cancer-inhibitory mechanisms. Her methodological contributions include hybrid clustering techniques and predictive model validation frameworks.
Professor Thomas Meier is a Visiting Professor at the Department of Life Sciences, Imperial College London (since 2015), and Director of the Centre for Structural Biology (2017–2021). He leads research on ATP synthase structure, drug targets for tuberculosis, and molecular mechanisms of disease. Previously, he was a Group Leader at the Max-Planck-Institute of Biophysics (2006–2015) and ETH Zurich's Institute of Microbiology. His work combines structural biology (X-ray crystallography, electron microscopy) with biochemical studies. Education: Dr. sc. nat. (2002) and Dipl. sc. nat. (1998) from ETH Zurich. Awards include the Wellcome Trust Investigator (2015–present). Research focuses on ATP synthase's role in energy conversion, drug development, and structural biology. His lab includes postdocs and students like Lisa Uhrig and Anthony Cheuk. Key affiliations: Centre for Structural Biology, Membrane Biology Group, and Bacterial Pathogenesis studies. Languages: German, English, French (fluent), Latin (read/write). Publications span structural biology, planetary science, and drug discovery. His work on ATP synthase inhibitors for TB has clinical implications, while astrophysical studies explore planetary formation via giant impacts.
George Perry is a Professor of Anthropology at Pennsylvania State University, with research intersections in Biology, Evolutionary Medicine, and Genomics. He is affiliated with the Huck Institutes' Center for Infectious Disease Dynamics, Ecology, Molecular Cellular and Integrative Biosciences, and Bioinformatics and Genomics programs. Perry directs the Anthropological Genomics Lab , focusing on paleogenomics and evolutionary adaptation. Research areas: anthropological genomics, parasite evolution, human body size transitions, and evolutionary medicine Key collaborations: international teams in Madagascar, Europe, and Africa Leadership: Bioinformatics and Genomics Chair (2019–2023) His 2025–2022 publications span evolutionary responses to invasive species, human migration health impacts, chemosensory gene adaptation, and primate genomic diversity. Notable methodological contributions include ancient DNA recovery and comparative paleogenomics. Perry advises graduate students like Vanessa Garcia and Annette Mercedes, with grants including NIH support for Cuban health disparity studies. Scientific leadership includes tenure-line promotions (2023) and NASA Space Grant collaborations.
Dana Pe'er is a Professor and Chair of the Computational and Systems Biology Program at the Sloan Kettering Institute (SKI) of Memorial Sloan Kettering Cancer Center. She is also an Investigator of the Howard Hughes Medical Institute and holds the Alan and Sandra Gerry Endowed Chair. Dr. Pe'er leads an interdisciplinary research group that combines advanced genomics approaches with machine learning to address fundamental questions in biomedical science, with particular focus on cancer biology, developmental biology, and immunology. Dr. Pe'er earned her PhD from Hebrew University in Jerusalem, Israel. Her academic journey includes a postdoctoral fellowship with George Church at Harvard Medical School. Before joining Memorial Sloan Kettering Cancer Center in 2016, she held faculty positions at Columbia University. Dr. Pe'er's research focuses on understanding cellular plasticity, the consequences of intra-tumor heterogeneity, cancer evolution and metastasis, and the mechanisms by which regulatory circuits go awry in disease. Her lab combines single-cell and spatial profiling technologies with machine learning approaches to investigate gene regulation, cellular plasticity, and cell-cell communication in the contexts of cancer, immunity, and development. They are particularly interested in how organisms develop from a single cell to generate diverse cell types, how epigenetic control rewires during development, and how cells communicate to execute multicellular responses. Analysis of Dr. Pe'er's recent publications reveals a strong focus on developing computational methods for single-cell and spatial genomics data analysis. Her work spans cancer types including pancreatic, prostate, colorectal, and breast cancer, with emphasis on tumor heterogeneity, metastasis mechanisms, and cellular plasticity. A significant portion of her research involves creating novel algorithms and tools like CellRank, REUNION, and SEACells that enable researchers to extract meaningful biological insights from complex genomic datasets. 2023 Class of 2023 Inductee - American Academy of Cancer Research (AACR) Academy 2023 Innovator Award - International Society for Computational Biology (ISCB) 2021 Fellow - International Society for Computational Biology (ISCB) Howard Hughes Medical Institute Investigator (2021) 2019 Ernst W. Bertner Memorial Award - University of Texas MD Anderson Cancer Center 2016 Lenfest Distinguished Faculty Award - Columbia University 2014 Director's Pioneer Award - National Institutes of Health 2014 Overton Prize - International Society for Computational Biology (ISCB) Dr. Pe'er is known for her dedicated mentorship approach, describing herself as "a mama bear" who cares deeply about her trainees while expecting independence, innovation, and hard work. She mentors numerous PhD students and postdocs in her lab. Her HHMI Investigator award provides approximately $9 million over seven years, enabling ambitious research directions. She also collaborates extensively with the Single-cell Analytics and Innovation Lab (SAIL) at MSK to generate new data from emerging technologies, working closely with wet-lab collaborators at MSK and beyond to apply computational methods to cutting-edge datasets across multiple disease areas. The Pe'er Lab is an interdisciplinary group of computational biologists with diverse backgrounds ranging from pure mathematics to clinical medicine. They work closely with wet-lab collaborators to apply their computational methods to cutting-edge datasets across cancer, immunology, and developmental biology. The lab is described as open, supportive, collaborative, and fun, with access to world-class facilities at the Sloan Kettering Institute. Dr. Pe'er's work continues to push the boundaries of computational biology and cancer research, with the ultimate goal of developing more effective, personalized therapies for cancer patients.
Hector Aguilar-Carreno is a Professor of Virology in the Department of Microbiology and Immunology at Cornell University's College of Veterinary Medicine, where he also serves as Associate Vice Provost in the Office of the Vice President for Research and Innovation. His research focuses on high-mortality paramyxoviruses including Nipah virus (NiV) and Hendra virus (HeV), as well as coronaviruses and other enveloped viruses. Dr. Aguilar-Carreno received his BS in Biochemical Engineering from Instituto Tecnologico de Tepic, Mexico, followed by an MS in Biology from California State University, Los Angeles, and a PhD in Biochemistry and Molecular Biology from the University of Southern California. He completed postdoctoral training in Virology at UCLA under Dr. Benhur Lee before becoming an Assistant Professor at Washington State University's Paul G. Allen School for Global Animal Health. His research spans four main areas: (1) Viral entry mechanisms, where his lab has identified novel domains in viral glycoproteins important for membrane fusion; (2) Viral egress, using multi-omics approaches to study viral assembly and budding; (3) Vaccine development using viral-like particles to generate neutralizing antibodies; and (4) Antiviral discovery targeting enveloped viruses. His lab employs innovative techniques including Flow Virometry and Raman Spectroscopy to study viral entry processes. Analysis of his recent publications reveals a strong focus on paramyxoviruses (particularly Nipah and Hendra viruses), coronavirus research, and the development of broad-spectrum antivirals. His work spans fundamental virology to translational applications, with numerous publications in high-impact journals including Nature, Science, and Cell Reports. President Elect of the American Society of Virology Chair of the American Society of Virology Diversity, Equity, and Inclusion committee Chair of the Cornell CVM Diversity Committee Director of the Cornell Program for Achieving Career Excellence Chair of 16 PhD student thesis committees Dr. Aguilar-Carreno has served on numerous scientific committees including the American Society for Virology Education Committee, the American Society of Microbiology Committee for Minority Education, and as a Standing Member of the VIR-A NIH study section. His leadership extends to chairing the Cornell CVM Diversity Committee and serving on the Cornell presidential postdoctoral fellowship committee, demonstrating significant commitment to diversity and mentorship in science.
Dr. Silu Wang is an Assistant Professor in the Department of Biological Sciences at the University at Buffalo. Her research focuses on speciation, adaptation, and forest evolutionary genomics, particularly in avian species. She leads the Forest Speciation Lab, studying the genomic and ecological mechanisms underlying species divergence in North American and global forest ecosystems. Her work integrates field studies, genomic analyses, and computational modeling to address biodiversity conservation challenges under climate change. Education: BS in Behavior Genetics and Neurobiology, University of Toronto MA in Ecology, Evolution and Behavior, University of Texas, Austin PhD in Zoology, University of British Columbia Postdoctoral Research at University of California Berkeley and UC Davis Research Interests: Dr. Wang investigates how hybridization, climate adaptation, and reproductive isolation shape avian biodiversity. Her lab uses old-growth forest bird species as models to study early-stage speciation processes, including mate choice, genetic incompatibilities, and mitochondrial-nuclear interactions. Key themes include understanding organismal responses to environmental changes and developing genomic tools for conservation prioritization. Lab and Teams: The Forest Speciation Lab collaborates with institutions globally, focusing on fieldwork in temperate and tropical forests. Current projects include studies on warbler hybrid zones, tinamou speciation, and the genomic architecture of mitonuclear coevolution. Teaching: Dr. Wang teaches courses on Speciation, Tropical Ecology, and Evolutionary Biology, emphasizing hands-on research training for students.
Jeremy Wang, PhD is an Assistant Professor in the Department of Genetics at the UNC School of Medicine . His research focuses on applying high-performance computational methods and machine learning to analyze high-throughput sequence data using long-read technologies (e.g., Oxford Nanopore) to advance precision personalized medicine . Key disease areas include Inflammatory Bowel Diseases (IBD) Respiratory Infectious Diseases His lab specializes in microbiome analysis , host-pathogen interactions , and computational genomics , working with collaborators in clinical, translational, and computational domains. His publications demonstrate expertise in long-read sequencing applications for Pediatric cancer classification SARS-CoV-2 genomic epidemiology Microbiome spatiotemporal dynamics Murine disease models Drosophilid genome assemblies Metagenomic bias analysis Collaborations span UNC and global institutions, with current work extending to clinical laboratory partnerships for pathogen sequencing and oral microbiome sampling methodology.
Lonny R. Levin is a Professor of Pharmacology at Weill Cornell Medical College , where he has worked since 2009. Collaborating extensively with Dr. Jochen Buck, he pioneered research on bicarbonate-regulated soluble adenylyl cyclase (sAC) , a critical enzyme in cAMP signaling. Education : B.S. from Cornell University (1983), Ph.D. from State University of New York at Stony Brook (1989) His research focuses on: cAMP signaling microdomains in mammalian cells Mitochondrial metabolism and pH sensing Sperm capacitation and energy regulation Nonhormonal contraceptive development via sAC inhibition Recent publications (2025-2023) highlight: Structural insights into sAC activation Metabolic adaptations during sperm capacitation Emerging role in corneal endothelium signaling Drug discovery for on-demand male contraception Grants from NIH (NIAID, NICHD) support his work on: Intravaginal rings for dual HIV/herpes prevention and contraception Metabolic communication in reproductive systems Signalosome regulation in mitochondria He maintains collaborations with institutions like EMD Millipore Corporation and co-founded Sacyl Pharmaceuticals, Inc. , holding proprietary interests in sAC-related intellectual property.
Prof. Dr. Ralph Bock serves as Director of Department 3: Organelle Biology, Biotechnology and Molecular Ecophysiology at the Max Planck Institute of Molecular Plant Physiology in Potsdam, Germany, where he also leads the Organelle Biology and Biotechnology research group. Previously, he held positions as C4 Professor for Plant Biochemistry and Biotechnology at the University of Münster (2001-2004) and Group Leader at the Institute of Biology III, University of Freiburg (1996-2001). His academic credentials include: Habilitation: University of Freiburg, 1999 Doctorate: University of Freiburg, 1996 Diploma: University of Halle, 1993 Prof. Bock's research focuses on plant molecular biology with particular emphasis on chloroplast biology, organelle biotechnology, and molecular ecophysiology. His work spans genetic engineering of plastids, photosynthesis research, plant biotechnology applications, and understanding organelle-nucleus communication. He has made significant contributions to developing chloroplast transformation systems and applying them to molecular farming, metabolic engineering, and understanding fundamental processes in plant cell biology. His research has important implications for sustainable agriculture, bioenergy, and pharmaceutical production, particularly through the development of plant-based systems for producing vaccines and therapeutic proteins. Analysis of Prof. Bock's recent publications (2023-2025) reveals a strong focus on chloroplast biology, genetic engineering, and molecular farming applications. His work spans fundamental research on organelle genetics, photosynthesis, and stress responses, as well as applied research on using plant and algal systems for biopharmaceutical production. A notable trend is the increasing use of advanced genetic engineering techniques, including CRISPR-based approaches, to manipulate organelle genomes. His research also shows growing interest in algal systems as alternative expression platforms for molecular farming, particularly red algae like Porphyridium for producing viral antigens and glycoproteins.
Jeff S Abramson is a Professor of Physiology in the David Geffen School of Medicine at the University of California Los Angeles (UCLA). His research focuses on the structural and functional characterization of membrane transport proteins, particularly sugar transporters and mitochondrial channels. He maintains an active laboratory investigating the molecular mechanisms of cellular transport processes. Dr. Abramson's primary research interests center on membrane transport proteins, with particular emphasis on sugar symporters and voltage-dependent anion channels (VDACs). His work combines structural biology, biophysics, and biochemistry to understand the molecular mechanisms of transport, including conformational changes during transport cycles, substrate recognition, and regulation by membrane potential. His research has significant implications for understanding metabolic disorders, mitochondrial function, and potential therapeutic targets. Analysis of Dr. Abramson's publication record reveals a consistent focus on membrane protein structure-function relationships over the past two decades. His work demonstrates expertise in X-ray crystallography, cryo-electron microscopy, and functional assays to characterize transport proteins. Recent publications show increasing emphasis on mitochondrial biology, particularly VDAC structure and function, while maintaining his longstanding interest in sugar transport mechanisms. His research bridges fundamental biophysical principles with potential biomedical applications in metabolic diseases. Dr. Abramson has been awarded multiple NIH grants supporting his research, including the R35GM135175 grant titled 'Deciphering molecular details of cellular sugar transport and their roles in disease' (2020-2024), R01GM124783 'Functional and structural studies of unique pathogenic transporters involved in glycobiology' (2017-2021), and R01GM078844 'Structural and functional characterization of sugar transporters in health and disease' (2006-2020). As Principal Investigator, Dr. Abramson has mentored numerous graduate students and postdoctoral researchers. His laboratory has made significant contributions to understanding the structure-function relationships of membrane transport proteins through collaborations with researchers across multiple disciplines. The lab utilizes advanced techniques including X-ray crystallography, cryo-EM, electrophysiology, and computational modeling to address fundamental questions about membrane protein mechanisms. Dr. Abramson's laboratory is part of UCLA's broader research ecosystem focused on structural biology and membrane protein research. His work intersects with several research centers at UCLA including those focused on metabolic diseases and structural biology. The lab maintains active collaborations with researchers specializing in biophysics, computational modeling, and disease mechanisms to translate basic findings into potential biomedical applications.
Martin Jastroch is a Professor at Stockholm University's Department of Molecular Biosciences, The Wenner-Gren Institute. His research focuses on the physiology and molecular mechanisms of energy metabolism from organism to molecule level. His primary research interests include: Energy metabolism physiology and molecular mechanisms Obesity and metabolic aspects Adipose tissue biology Mitochondrial mechanisms Thermogenesis and brown fat function Metabolic regulation in health and disease Professor Jastroch's research spans multiple disciplines, connecting molecular mechanisms with whole-organism physiology. His work on mitochondrial bioenergetics and thermogenesis has contributed significantly to understanding how energy metabolism is regulated across different biological scales. Recent publications show a growing interest in the evolutionary aspects of thermogenesis and the role of brown adipose tissue in metabolic diseases, with particular focus on UCP1 function, mitochondrial adaptations, and metabolic reprogramming in disease states. His scientific contributions include important findings on: UCP1 (Uncoupling Protein 1) function and regulation Mitochondrial bioenergetics in different tissue types Evolutionary aspects of mammalian thermogenesis Metabolic regulation in obesity and related disorders Links between mitochondrial dysfunction and neurodegenerative diseases Professor Jastroch leads 'Group Jastroch' at Stockholm University, where his team investigates the complex interplay between cellular energy metabolism and whole-body physiology, with implications for understanding and treating metabolic disorders.
