جستجوی استاد راهنمای دانشگاهی

Joshua J. Solanoمشاهده پروفایل

دانشیار

• Emergency Medicine
• Geriatric Emergency Care
• Medical Education
• +۴ مورد دیگر

Joshua J. Solano, M.D., FAAEM is an Associate Professor of Emergency Medicine and Clerkship Director for the Emergency Medicine Residency program at the Florida Atlantic University Charles E. Schmidt College of Medicine. As Clerkship Director, he works alongside residents to promote best practices for emergency department patient care. Dr. Solano is board certified in emergency medicine and maintains active membership in the American College of Emergency Physicians and the American Academy of Emergency Medicine. Dr. Solano's educational background includes a BS in Biology and BA in History from Duke University, followed by his MD from the University of Florida. He completed his emergency medicine residency at Beth Israel Deaconess Medical Center in Boston and served on faculty at Harvard Medical School as an instructor and assistant program director before joining FAU. In his final year in Boston, he completed the Rabkin Medical Education Fellowship. Dr. Solano's research focuses on geriatric emergency medicine, particularly head trauma management in elderly patients, anticoagulation risks, and emergency department quality assurance. His recent publications demonstrate a strong emphasis on developing clinical decision rules for geriatric head trauma and understanding medication interactions in older emergency patients. He has also contributed significantly to medical education literature, developing innovative residency training curricula. His scholarly work shows a clear progression toward establishing evidence-based guidelines for geriatric emergency care, with numerous publications on intracranial hemorrhage risk assessment, anticoagulation management, and fall prevention strategies. Dr. Solano's research bridges clinical practice with educational innovation, making significant contributions to both patient care protocols and emergency medicine training. 2017: Attending Role Model Award, Beth Israel Deaconess Medical Center 2016-2017: Rabkin Medical Education Fellowship 2011: Alpha Omega Alpha Medical Honor Society 2011: Chapman Humanism Society 2010: Equal Access Clinic Service Award 2010: Lawrence M. Goodman Award for Medical Student Research 2010: Community Service Award As Clerkship Director, Dr. Solano oversees medical student education in emergency medicine and has implemented electronic evaluation systems that have increased the quality and quantity of student assessments. His clinical work includes staff positions at Bethesda East Hospital and Delray Medical Center. Dr. Solano's research program demonstrates strong institutional support through multiple publications and ongoing investigations into geriatric emergency care protocols.

• Metabolic Signaling
• Pancreatic Islet Biology
• Signal Transduction Pathways
• +۴ مورد دیگر

Dr Amin Ardestani , Senior Lecturer in Metabolic Signaling at the Biomedical Institute for Multimorbidity (BIM), Hull York Medical School (HYMS) , specializes in unraveling molecular mechanisms of pancreatic β-cell failure in diabetes. His research program identifies novel therapeutic targets through signal transduction studies in metabolic disorders. Bachelor's in Biology, Tarbiat Moalem University (2004) Master's in Biochemistry, Institute of Biochemistry and Biophysics (2007) PhD in Biology, University of Bremen (2013) Junior Group Leader at University of Bremen (2014-2023) Research focuses on Hippo and mTOR signaling pathways in β-cell biology, autoimmunity, and regeneration. His work bridges mechanistic biology with drug discovery for diabetes, with significant findings on PHLPP1/2 phosphatases and MST1/2 kinases. Recent publications highlight therapeutic strategies for β-cell protection , including small molecule inhibitors (e.g., MST1/2 inhibitors) and metabolic enzyme modulation (LDHA). Collaborative studies explore SARS-CoV-2 interactions with pancreatic cells and cross-talk between acinar and β-cells in diabetes. 2019 JDRF Advanced Postdoctoral Fellowship 2018 Impulse grant & Career Advancement Award 2017 Early Investigators awards (Endocrine Society, EFSD/Lilly Programme) 2014 Albert Renold Fellowship & Bremer Studienpreis Professional roles include Editorial Board Member at Scientific Reports and Associate Editor at Frontiers in Endocrinology . He reviews grants for DFG, Diabetes UK, and ISF, and evaluates manuscripts for top-tier journals like Cell Metabolism and Nature Communications.

Geir Selbækمشاهده پروفایل

استاد

• Dementia Research
• Geriatric Psychiatry
• Neurodegenerative Diseases
• +۴ مورد دیگر

Geir Selbæk is a Professor II at the University of Oslo in the Department of Geriatric Medicine . His research focuses on dementia , neurodegenerative diseases , and aging-related mental health , with extensive work on the HUNT study —a large Norwegian population-based cohort. He investigates risk factors like depression , loneliness , metabolic health , and social determinants to understand dementia progression. Key research areas: Dementia epidemiology, geriatric mental health, neurodegenerative disease, aging, cognitive impairment Recent publications analyze AI in diagnostics, genetic risk scores, social media's role in pandemic isolation, and metabolic markers Collaborations Selbæk collaborates with international teams across Alzheimer's & Dementia , Nature Genetics , PLOS ONE , and other high-impact journals. His work integrates epidemiological data , neuropsychological testing , and molecular biology to address dementia prevention and care.

Nikolaus Rajewskyمشاهده پروفایل

استاد

• RNA Biology
• Gene Regulation
• Single-Cell Transcriptomics
• +۶ مورد دیگر

Nikolaus Rajewsky is a leading Professor at the Max Delbrück Center for Molecular Medicine (MDC) and Charité – Universitätsmedizin Berlin , where he founded and directs the Berlin Institute for Medical Systems Biology (BIMSB) . His lab integrates experimental (biochemistry, molecular biology) and computational (bioinformatics, physics) approaches to study RNA regulation in gene expression , with applications to developmental biology, regeneration, neurodegenerative diseases, and cancer . Using model systems like C. elegans , planaria, and human brain organoids, his team pioneers cutting-edge methods such as MirDeep , DistMap , and FLAM-seq for RNA analysis. His research focuses on single-cell transcriptomics , spatial RNA sequencing , and circular RNA (circRNA) regulation , revealing novel roles for circRNAs like CDR1as in neuropsychiatric disorders. Recent work includes 3D tumor microenvironment mapping and computational modeling of RNA metabolism in diseases. Scientific Awards : Gottfried Wilhelm Leibniz Prize (2012) EMBO Membership (2010) Honorary PhD, Sapienza University of Rome (2014) Berlin Science Award (2009) His team's recent articles highlight breakthroughs in 3D spatial transcriptomics , circRNA degradation mechanisms , and mitochondrial disease modeling using human brain organoids. The lab actively collaborates with clinical partners across Charité and European institutions, driving the LifeTime initiative for cell-based interceptive medicine.

Jingwei Chengمشاهده پروفایل

استادیار

• Virology
• Cancer Biology
• Epigenetics
• +۷ مورد دیگر

Jingwei Cheng is an Assistant Professor in the Department of Molecular, Cellular, and Biomedical Sciences at the University of New Hampshire's College of Life Sciences and Agriculture. His research focuses on understanding the molecular mechanisms of DNA tumor viruses, particularly polyomaviruses, and their roles in cancer development. Specifically, his work investigates how Merkel cell polyomavirus (MCV) contributes to Merkel cell carcinoma (MCC) through interactions with tumor suppressors like p53 and RB, and the epigenetic regulation of transcriptional complexes. Cheng completed his B.S. in Biotechnology at Peking University and earned his Ph.D. in Biochemistry from the University of Illinois at Urbana-Champaign. His lab explores viral oncogenesis, MYC-driven cancers, and the interplay between transcriptional activation (via the SLaP complex) and repression (via PRC1.6) in neuroendocrine tumors. He also studies RNA methylation and splicing regulation in cancer cells with MYC overexpression. Cheng's research has identified druggable targets such as PRMT5 and the Tip60-p400 complex, aiming to develop therapies targeting MYC-driven cancers. His work bridges virology and cancer biology, with implications for neuroendocrine tumors like MCC and small cell lung cancer. He teaches courses on virology and cancer biochemistry and mentors students in molecular oncology research. His recent publications focus on viral mechanisms of immune evasion, molecular markers in MCC subtypes, and the therapeutic potential of targeting viral and epigenetic pathways. Cheng collaborates on genome-scale CRISPR screens and omics technologies to uncover cancer dependencies.

Shaji K Chackoمشاهده پروفایل

دانشگاهی

• Glucose Metabolism
• Gluconeogenesis
• Glycogenolysis
• +۱۲ مورد دیگر

Shaji K Chacko, Ph.D., is an Instructor in the Department of Pediatrics – Nutrition at Baylor College of Medicine, where he leads an independent research laboratory at the USDA/ARS Children's Nutrition Research Center in Houston, Texas. His work focuses on metabolic regulation, particularly glucose production pathways in health and disease. BS, Nagpur University (1990) MS, Barkatullah University (1992) MS, University of Houston, Clear Lake (2000) PhD, University of Groningen (2011) Dr. Chacko's research centers on glucose metabolism , specifically gluconeogenesis and glycogenolysis , using stable isotope tracers and mass spectrometry. His lab investigates metabolic dysfunctions in conditions such as insulin resistance, type 2 diabetes, and post-surgical states, with a strong focus on pediatric and neonatal populations. He also studies total energy expenditure using the doubly labeled water method in free-living subjects. The 15 most recent publications reflect a consistent focus on metabolic regulation, particularly in insulin resistance , obesity , diabetes , and parenteral nutrition . Key themes include hormonal regulation (e.g., leptin), amino acid metabolism (glycine, BCAA), liver function, and therapeutic interventions like metformin and nutritional supplements. His work frequently involves translational models, including human clinical studies and genetically modified animal models. Dr. Chacko has not received any explicitly mentioned scientific awards in the provided texts. He mentors lab members such as Zhensheng Chen (Research Associate) and collaborates extensively with clinicians and scientists, including M.W. Haymond and F. Jahoor. While no specific grants are listed, his research likely involves externally funded projects given the scope and equipment required for stable isotope and mass spectrometry studies. His lab benefits from the state-of-the-art facilities at the Children's Nutrition Research Center, including a metabolic kitchen, greenhouse, and advanced instrumentation. The Shaji Chacko Lab is embedded within the USDA/ARS Children's Nutrition Research Center, a multidisciplinary hub housing elite scientists conducting cutting-edge research in pediatric nutrition and metabolism. The center provides extensive resources including specialized laboratories, research accommodations, and a collaborative scientific environment.

Feyruz V. Rassoolمشاهده پروفایل

استاد

• DNA damage and repair
• Genomic instability
• Epigenetic therapy
• +۷ مورد دیگر

Feyruz V. Rassool is a Professor at the University of Maryland School of Medicine, with primary appointment in Radiation Oncology. She serves as Co-director of the Experimental Therapeutics Program at the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC) and holds an adjunct Associate Professor position at VARI’s Center for Epigenetics. Her research focuses on DNA damage/repair pathways in cancer, particularly their therapeutic exploitation through PARP and DNMT inhibitors. Education: B.Sc. in Human Genetics (1983, University College London), Ph.D. in Biological Sciences (1990, Royal Postgraduate Medical School) Postdoctoral Training: University of Chicago (1990-1994) Her work explores the intersection of DNA repair , epigenetics , and mitochondrial dysfunction to develop novel therapies for breast, ovarian, lung, and leukemias. Key projects include STING-dependent interferon signaling , pathogen mimicry in cancer cells, and metastasis suppression through PARPi/epigenetic combinations. Dr. Rassool is part of the SU2C Epigenetics Dream Team and has secured multiple grants from NCI, NIH, and the Adelson Medical Research Foundation. Her recent preclinical studies with PARP/DNMT inhibitors are being translated into Phase I/II trials for AML and TNBC. Scientific Awards Ziskin Award (2012) NCI-SPORE Grant Co-Leader NIH/NCI P30 CA134274 Support Grant She has mentored 13 PhD/postgraduate researchers and collaborates on clinical trials with Pfizer, VARI-SU2C, and ASTRO. Her lab employs techniques like DNA repair assays , RNAseq , and mouse xenograft models to investigate mechanisms of action for epigenetic drugs.

• Cerebral Microcirculation
• Vascular Biology
• Endothelial Cell Function
• +۶ مورد دیگر

William Mayhan is a Professor in Biomedical Sciences at the University of South Dakota . His research focuses on cerebral microcirculation and vascular biology , particularly examining endothelial cell function in disease states like diabetes and alcohol consumption. Education: PhD in Biomedical Sciences, University of Nebraska Medical Center (1983) Post-Doctoral Fellowship, University of Iowa (1985) BS in Biology, Creighton University (1977) His work investigates blood-brain barrier permeability and cerebral vasculature responses to hypertension, diabetes, and alcohol. Key findings include mechanisms of nitric oxide synthase (NOS) dysfunction and oxidative stress in diabetic and alcoholic models. Recent publications analyze prenatal alcohol exposure effects on cerebral arterioles and CB2 receptor agonists for vascular protection in diabetes. His studies span in vivo models, potassium channel dynamics , and inflammatory mediators in stroke pathogenesis.

James Turnerمشاهده پروفایل

دانشیار

• Exercise Immunology
• Cancer Immunology
• Ageing and Immunosenescence
• +۳ مورد دیگر

James Turner is an Associate Professor in Exercise Physiology and Immunology at the University of Birmingham's School of Sport, Exercise and Rehabilitation Sciences. Previously, he held roles at the University of Bath as a Lecturer (Assistant Professor) from 2013 to 2018 and promoted to Senior Lecturer (Associate Professor) in 2018 before moving to Birmingham in 2022. His research focuses on lifestyle impacts on ageing and chronic disease, particularly adipose tissue immunology and cancer immunology (e.g., breast cancer). He leads projects examining obesity, immune system ageing, and factors influencing cancer treatment outcomes. His work aligns with UN Sustainable Development Goals related to health and well-being. Education: BSc (Hons) Sport and Exercise Science (University of Bath, 2006); PhD in Exercise Biochemistry and Immunology (University of Birmingham, 2011). Post-doctoral training in cancer immunology followed. He has mentored 9 PhD/MSc students as lead or co-supervisor and contributed to grants from bodies like Cancer Research UK and the Biotechnology and Biological Sciences Research Council. Current research includes projects on adipose tissue inflammation and muscle mass regulation in older adults. Labs/Teams: Active in collaborative projects with institutions globally, focusing on exercise immunology and cancer treatment efficacy. Editor for journals like Frontiers in Physiology and International Journal of Sport Nutrition and Exercise Metabolism .

Stelios Andreadisمشاهده پروفایل

استاد

• Stem Cell Engineering
• Tissue Engineering
• Cell Adhesion Signaling
• +۳ مورد دیگر

Stelios Andreadis is the SUNY Distinguished Professor of Chemical and Biological Engineering at the University at Buffalo, affiliated with the School of Engineering and Applied Sciences. He directs the Cell, Gene and Tissue Engineering Center and previously led the Stem Cells in Regenerative Medicine (SCiRM) Training Program. His research focuses on stem cell bioengineering, vascular and gland tissue engineering, and biomaterials design. He holds a PhD in Chemical Engineering from the University of Michigan and has been funded by NIH, NSF, and NYSTEM, totaling over $20M. His awards include the NSF CAREER Award, SUNY Chancellor’s Excellence in Scholarship, and AIMBE and BMES Fellowships. Research interests span stem cell rejuvenation, cell-free vascular grafts, and metabolic reprogramming. He has published 140+ papers and advised 28 PhD students, many now in academia or industry. His lab co-founded Angiograft, LLC to commercialize vascular grafts. Key achievements include developing self-healing vascular grafts and demonstrating monocyte recruitment for vascular regeneration. His work bridges basic science and clinical applications in regenerative medicine.

Mercedes Taylorمشاهده پروفایل

استادیار

• Inorganic and Organic Synthesis
• Porous Materials
• Supramolecular Assembly
• +۳ مورد دیگر

Dr. Mercedes Taylor is an Assistant Professor in the Department of Chemistry and Biochemistry at the University of Maryland, College Park. She holds the Nathan Drake Faculty Fellowship. Previously, she was a Jill Hruby Fellow in National Security Science and Engineering at Sandia National Labs (2018–2021) and a Post-Baccalaureate Intramural Research Training Awardee at the NIH (2011–2013). She earned her Ph.D. in Chemistry from UC Berkeley (2018) and a B.A. in Chemistry from Amherst College (2011). Her research focuses on synthesizing novel materials like supramolecular cages, covalent organic frameworks, and porous polymers for applications in water purification and critical metal capture. Her lab emphasizes controlling material structure to achieve selectivity for target molecules and enhance aqueous stability. Key projects include ion separations, environmental remediation, and energy storage solutions. Dr. Taylor’s work has been recognized through awards such as the 2024 Doctoral New Investigator Award (ACS), 2023 DOE Separation Science Core Award, and the 2023 Moore Inventor Fellowship. She mentors a dynamic research group, including graduate students and post-baccalaureate researchers, and actively engages in interdisciplinary collaborations. Her lab is part of the Taylor Group at UMD, which develops advanced materials for ion capture and water treatment. Alumni of her group include researchers at Sandia National Labs and academic institutions, contributing to both industry and academia.

George Hendersonمشاهده پروفایل

استاد

• Developmental Neuroscience
• Neurotoxicity
• Oxidative Stress
• +۳ مورد دیگر

George Henderson is a Professor at the Texas Tech University Health Sciences Center in the Department of Pharmacology & Neuroscience . His research focuses on the neurotoxic effects of ethanol and environmental toxins during development, particularly mechanisms of apoptosis and oxidative stress in the brain and placenta. Primary Affiliation: Texas Tech University Health Sciences Center Research Areas: Developmental neuroscience, neurotoxicity, oxidative stress, fetal alcohol spectrum disorder, nanoparticle drug delivery Research Trends: His publications from 1972–2023 show sustained expertise in ethanol-induced developmental damage, placental drug transport mechanisms, and antioxidant therapeutic strategies. Recent work (2023) explores chlorogenic acid as a neuroprotective agent via NFATc4/CSE pathways. Key Collaborations: Institute for One Health Innovation and translational neuroscience teams at TTUHSC.

Bjoern Bauerمشاهده پروفایل

استاد

• Neuroscience
• Alzheimer’s Disease
• Blood-Brain Barrier Physiology
• +۳ مورد دیگر

Bjoern Bauer, PhD is a Professor in the Department of Pharmaceutical Sciences at the University of Kentucky, affiliated with the Sanders-Brown Center on Aging. His research focuses on blood-brain barrier (BBB) biology, Alzheimer’s disease mechanisms, and drug delivery strategies for neurological disorders. Bauer’s work explores how BBB dysfunction contributes to neurodegenerative diseases and cancer, with particular attention to efflux transporters like P-glycoprotein (ABCB1) and their roles in drug resistance and amyloid beta pathology. Key research areas include: 1) BBB leakage and its role in Alzheimer’s disease progression, 2) development of therapeutic strategies to modulate BBB transporters, 3) preclinical models of glioblastoma and neurodegeneration, and 4) biomarker discovery for early disease detection. His lab utilizes advanced in vitro BBB models, transgenic mouse models (e.g., 5xFAD), and imaging techniques to study these processes. Bauer’s contributions span over 40 peer-reviewed publications since 2001, with recent work emphasizing oxidative stress mechanisms, tumor drug resistance, and translational approaches to BBB targeting. Current efforts include investigating S100β as a plasma biomarker and exploring proteasome inhibition as a therapeutic avenue for restoring BBB integrity. He leads the Bauer-Hartz Lab, collaborating extensively with neurologists, oncologists, and pharmacologists to advance CNS drug delivery technologies. He holds a PhD in Pharmacology and has been a faculty member at the University of Kentucky since joining Sanders-Brown in [year not explicitly stated]. His research is supported by grants focusing on BBB biology, Alzheimer’s disease, and cancer pharmacology.

• Redox Biology
• Cancer Research
• Drug Metabolism
• +۴ مورد دیگر

Zhiwei Ye is an Associate Professor in the Department of Pharmacology & Immunology at the College of Medicine, Medical University of South Carolina. His research focuses on redox biology, cancer mechanisms, and drug metabolism with a particular emphasis on mitochondrial function, oxidative stress, and therapeutic resistance. He holds a PhD in Pharmaceutical Science from Katholieke Universiteit Leuven (Belgium, 2009) and prior degrees from Zhejiang University (China). PhD in Pharmaceutical Science, 2009 – Katholieke Universiteit Leuven, Belgium Master in Pharmaceutical Science, 2005 – Katholieke Universiteit Leuven, Belgium Master in Medicine, 2003 – Zhejiang University, China B.S. in Pharmacy, 2000 – Zhejiang University, China Dr. Ye’s research explores how redox regulation impacts cancer progression, drug resistance, and metabolic disorders. His work integrates enzymology (e.g., GSTP, PDI), mitochondrial dynamics, and zebrafish models to study mechanisms like S-glutathionylation, VDAC targeting, and drug-transporter interactions. Recent studies highlight novel therapeutic strategies for hepatocellular carcinoma, melanoma, and myeloma through modulation of redox pathways. Publications emphasize translational research bridging basic biology and clinical applications, including drug development (e.g., Telintra) and understanding treatment resistance in malignancies. His work also addresses metabolic disease mechanisms, such as hepatic steatosis and drug-induced renal toxicity. No scientific awards explicitly mentioned in provided texts. Active in grant-funded research areas like cancer biology and redox signaling. Collaborates on projects involving drug-transporter profiling in hepatocytes and cellular stress responses.

Naftali Razمشاهده پروفایل

استاد

• Human Brain Aging
• Cognitive Aging
• Metabolic Risk Factors
• +۴ مورد دیگر

Naftali Raz is a Professor of Psychology at Stony Brook University, specializing in Integrative Neuroscience. He holds a Ph.D. from the University of Texas at Austin (1985) and a B.A. from the Hebrew University of Jerusalem (1979). His research focuses on understanding age-related changes in the brain and cognition, particularly exploring metabolic, vascular, and inflammatory risk factors influencing cognitive aging. He employs neuroimaging techniques such as MRI, MRS, and fMRI to study brain structure, function, and metabolism in healthy aging populations. Raz’s research emphasizes the 'FRIENDS' model (Free-Radical Induced Energetic and Neural Decline in Senescence), linking aging to energy production decline. His work includes longitudinal studies on brain atrophy, myelin content, and iron accumulation. He investigates how physiological risk factors like cardiovascular disease and metabolic syndrome impact neurocognitive trajectories. Current grants include NIA funding for neural correlates of cognitive aging and hippocampal glutamate modulation studies. Education: Ph.D. in Psychology, University of Texas at Austin (1985) B.A. in Psychology, Hebrew University, Jerusalem, Israel (1979) Labs/Facilities: Integrative Neuroscience Group, SCAN Center (Stony Brook Advanced Neuroimaging) His publications span over three decades, with recent works on recognition memory strategies, hippocampal subfield analysis, and cerebral blood flow dynamics. Collaborations include multi-institutional projects on neuroimaging protocols and aging mechanisms.