جستجوی استاد راهنمای دانشگاهی

Phyllis Fung-Yi Cheungمشاهده پروفایل

پژوهشگر

• Tumor Heterogeneity
• Drug Resistance
• Cancer Immunology
• +۴ مورد دیگر

Dr. Phyllis Fung-Yi Cheung is a researcher at the German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, affiliated with University Hospital Essen. Her work focuses on spatiotemporal tumor heterogeneity and therapy-induced dynamics in the tumor microenvironment (TME), particularly in solid cancers like pancreatic and hepatocellular carcinoma. Research Interests : Therapy-induced dynamics in tumor microenvironment Spatial multi-omic analysis of cancer-associated fibroblasts Translational applications for drug resistance in solid tumors Publication Trends : Her research spans drug resistance mechanisms, cancer immunology, and TME interactions. Key areas include pancreatic cancer, hepatocellular carcinoma, fibroblast activation, and immune evasion strategies using progranulin and MHCI regulation. Scientific Awards : AIO Science Award 2022 Labs & Collaborations : Leads the DKTK research group on spatiotemporal tumor heterogeneity, collaborating across institutions to integrate dynamic and spatial heterogeneity studies for precision oncology.

• Mitochondrial physiology
• Exercise physiology
• Metabolism
• +۶ مورد دیگر

Steen Larsen is an Associate Professor in the Department of Biomedical Sciences at the University of Copenhagen's Faculty of Health and Medical Sciences. He also holds a Visiting Professor position at the Medical University of Bialystok in Poland since 2018. Dr. Larsen leads the Exercise and Muscle Center for Healthy Aging and has established a laboratory specializing in mitochondrial analysis across various tissues since becoming an Assistant Professor in 2015. His educational background includes a Doctor of Medical Sciences (2014), M.Sc. in Human Physiology (2008), and B.Sc. in Chemistry (2007), all from the University of Copenhagen. Dr. Larsen's primary research focuses on understanding how lifestyle interventions (exercise, diet, drugs) affect whole-body metabolism and mitochondrial function, with particular attention to skeletal muscle and adipose tissue. His laboratory primarily studies human subjects but occasionally employs animal models. Dr. Larsen's recent publications (2024-2025) demonstrate a strong emphasis on mitochondrial physiology across various conditions including diabetes, obesity, statin treatments, and aging. His work spans from basic molecular mechanisms to clinical applications, with publications appearing in high-impact journals such as Cell Metabolism, Diabetologia, and Nature Communications. His research consistently connects mitochondrial function with metabolic health outcomes across different populations. As an educator, Dr. Larsen teaches medical students during their 4th and 5th semesters and supervises numerous bachelor's, master's, and currently four PhD students. He is frequently invited to present at major conferences including the European College of Sport Science and the American College of Sports Medicine.

Juan José Lasarte Sagastibelzaمشاهده پروفایل

استاد

• Immunology
• Antitumor Immunotherapy
• Antiviral Immunotherapy
• +۴ مورد دیگر

Juan José Lasarte Sagastibelza is a Full Professor of Immunology at the University of Navarra, affiliated with the School of Medicine and the Department of Internal Medicine. He serves as a Principal Investigator in the Immunomodulation and Tumor Microenvironment group at Cima Universidad de Navarra, while also contributing to the Cancer Center Clínica Universidad de Navarra. PhD in Sciences, University of Navarra (1992) Bachelor in Biological Sciences, University of Navarra (1988) Research Interests: His work focuses on immunology and the development of antiviral/antitumor immunotherapies. Key areas include: Characterization of mechanisms inducing cellular/humoral immune responses Development of synthetic peptides as biological process inhibitors Study of tumor immune evasion and regulatory T cell function CAR-T cell therapies and EDA vaccination platform (licensed to Formune Vaccines) Scientific Contributions: He has co-invented 20 patents, including p144 (anti-TGF-beta peptide for systemic sclerosis clinical trial), and developed CD25-targeted nanoliposomes for tumor regression. His research spans EU Horizon 2020, Carlos III Health Institute, and private-industry collaborations (e.g., Hoffman-La Roche). Teaching & Leadership: He has supervised 15 PhD theses (5 awarded Extraordinary Doctorate) and authored 6 books. Active in academic leadership as co-director of the Immunology and Immunotherapy Program and coordinator of the Spanish Network of Cancer Immunotherapy (REINCA).

• TGF-β family signaling
• Multiple myeloma
• Cancer research
• +۷ مورد دیگر

Toril Holien is Professor at the Department of Biomedical Laboratory Science, Faculty of Natural Sciences, Norwegian University of Science and Technology (NTNU). Her research centers on TGF-β family signaling in multiple myeloma and other cancers, dissecting how ligands such as TGF-β, activins, BMPs and GDFs modulate SMAD-dependent transcription and apoptosis. She leads a vibrant group that welcomes graduate and visiting students, and she has co-authored >50 peer-reviewed papers since 2008. Research Interests Transforming growth factor-β (TGF-β) superfamily signaling in cancer Multiple myeloma biology and therapy resistance SMAD1/5-mediated apoptosis and c-MYC repression Tumor microenvironment, angiogenesis and dissemination Bone morphogenetic proteins (BMPs) and bone disease in myeloma Translational use of photodynamic therapy and extracorporeal photopheresis Her recent publications reveal a translational trajectory spanning in-vitro mechanistic studies, pre-clinical mouse models and early-phase clinical trials. A dominant theme is the exploitation of BMP/SMAD signaling to overcome myeloma cell survival, alongside biomarker-driven prediction of drug sensitivity. Scientific Recognition Principal Investigator on multiple national and international projects Extensive collaboration network evidenced by multi-institutional publications Invited reviews in Cytokine & Growth Factor Reviews and other high-impact journals Advising & Grants Current PhD students: Md Abu Hanif (Edan), Eli Svorkdal Hess Current master’s students: Iben Qiu Yang Brøgger, Fenne Pien Breukink Former graduates: Ingrid Quist-Løkken (PhD/MD 2025), Clara Andersson-Rusch (PhD 2024), Oddrun Elise Olsen (PhD 2017 & 2020) Hosts Erasmus and visiting trainees annually Her laboratory is embedded within NTNU’s translational cancer research environment, offering cutting-edge facilities for cell biology, molecular profiling and animal models.

• Neuromuscular physiology
• Synaptic plasticity
• Skeletal muscle regeneration
• +۶ مورد دیگر

Paola Lorenzon is an Associate Professor of Physiology at the University of Trieste 's Department of Life Sciences since 2002. She coordinates the International Master's Degree in Neuroscience , serves as Coordinator of the OPBA program , and holds key roles in multiple PhD cycles including Neuroscience and Cognitive Science (XXVIII to XXXVIII cycles) and Biology (SM50). Her research focuses on neuromuscular plasticity , aging effects, and microgravity adaptation mechanisms. Education : Bachelor's in Biological Sciences and PhD in Biochemistry from University of Trieste Research Experience : University of Milan, San Raffaele Milan, University of Ljubljana, University of Bonn Her research spans three main areas: neuromuscular junction plasticity , electrostimulation protocols for muscle regeneration, and Piezo1 ion channels in mechanotransduction. Current projects funded by the Italian Space Agency (MIAG, NEMUSY) investigate muscle atrophy in spaceflight and aging. Notable collaborations include working with Annalisa Bernareggi (electrophysiology), Marina Sciancalepore (electrostimulation), and Alessandra Bosutti (project coordination). Her lab employs primary satellite cell cultures , electrophysiology , and mechanotransduction studies to explore muscle regeneration mechanisms.

Mayumi Ito Suzukiمشاهده پروفایل

استاد

• Pharmacology
• Stem Cell Biology
• Dermatology
• +۳ مورد دیگر

Mayumi Ito Suzuki is a Professor at the Grossman School of Medicine, New York University , with dual appointments in the Ronald O. Perelman Department of Dermatology and the Department of Cell Biology . Her research focuses on stem cell biology , skin regeneration , and melanocyte dynamics . Education: PhD from Nagoya University Research Interests: Mayumi's work spans hair follicle neogenesis , melanocyte stem cell behavior , and nichemechanics . Key areas include: Role of β-catenin and Hedgehog signaling in skin regeneration Stem cell aging in the dermal niche Interactions between immune cells and skin tissue during wound healing Mechanisms of melanoma metastasis and pigmentation disorders Publication Trends: Her recent studies (2020–2025) emphasize dermatology , cell biology , and regenerative medicine , with subtopics like Wnt signaling , stem cell plasticity , and fibrotic healing . Advising & Grants: While specific students are not listed, her work has been supported by grants for early melanoma metastasis research and chronic wound healing studies . She collaborates extensively in multidisciplinary teams investigating skin biology and aging.

Rachelle Crosbieمشاهده پروفایل

استاد

• Duchenne muscular dystrophy
• Protein biochemistry
• Muscle physiology
• +۵ مورد دیگر

Rachelle Crosbie is a Professor and Department Chair at the University of California, Los Angeles (UCLA), specializing in Integrative Biology and Physiology. Her research focuses on Duchenne muscular dystrophy (DMD), sarcospan, and extracellular matrix interactions in muscle health and disease. She earned her B.S. in Biochemistry from Texas A&M University (1989) and her Ph.D. in Biochemistry from UCLA (1994). Postdoctoral work was conducted at the University of Iowa Carver College of Medicine, supported by the Muscular Dystrophy Association. Her lab investigates sarcospan's role in ameliorating dystrophic muscle by activating compensatory mechanisms. Research includes developing small molecule therapies, in vitro platforms for fibrosis studies, and multi-omics approaches to cytoskeletal remodeling. She leads an NIH T32 training grant for muscle research. Scientific awards include the UCLA Chancellor’s Distinguished Teaching Award, Coalition Duchenne Lotus Award, and National Academies Education Scholar recognition. She developed an online DMD course for UC campuses and contributed to education research on student engagement in asynchronous learning.

Kate Beecher Matthewsمشاهده پروفایل

پژوهشگر ارشد

• Breast Cancer
• Neuroscience
• Brain Metastasis
• +۷ مورد دیگر

Dr. Kate Beecher Matthews is an Early Career Postdoctoral Research Fellow at the University of Queensland's UQ Centre for Clinical Research within the Faculty of Health, Medicine and Behavioural Sciences . She works in the Molecular Breast Pathology Lab collaborating with Prof. Sunil Lakhani, A/Prof Amy McCart Reed, A/Prof Peter Simpson, and Dr. Vaibhavi Joshi. Masters (Research) of Biomedical Science, Queensland University of Technology (2018) Doctor of Philosophy, Queensland University of Technology (2022) Dr. Matthews focuses on breast cancer and brain metastasis , with a unique interest in the interaction between the nervous system and breast cancer cells in the brain. Her work integrates neuroscience with oncology , particularly examining serotonin and dopamine signaling in neurocognitive effects of dietary factors and fetal growth restriction . Her recent publications analyze neuroinflammation from high-sugar diets, genomic landscapes of breast cancers, and neurotransmitter regulation in metabolic disorders. She also contributes to neuroscience education through virtual dissection tools. Dr. Matthews is available for research supervision and leads projects on TSPO biomarkers and peer review dynamics in scientific publishing. Her lab work investigates neuroprotective strategies for fetal growth restriction and neural circuits in appetite regulation.

Maria Castroمشاهده پروفایل

استاد

• Neuro-oncology
• Glioblastoma research
• Brain tumor treatment
• +۵ مورد دیگر

Maria Castro is a Professor in the Department of Neurosurgery at the University of Michigan Medical School, where she leads groundbreaking research in neuro-oncology with a specific focus on brain tumor treatment and glioblastoma research. Her work bridges laboratory science with clinical applications, developing innovative therapies for some of the most challenging brain cancers. Dr. Castro's research primarily centers on developing novel therapeutic approaches for glioblastoma and other malignant brain tumors. Her work spans multiple cutting-edge areas including nanoparticle therapy for brain tumors, oncolytic virotherapy, epigenetic reprogramming in gliomas, and artificial intelligence applications in neurosurgery. She has made significant contributions to understanding how cholesterol metabolism affects glioma progression and has developed HDL nanodisc technology to target brain tumors. Her research on oncolytic viruses has opened new avenues for cancer immunotherapy, while her work on FastGlioma represents a major breakthrough in intraoperative brain tumor detection technology. Analysis of Dr. Castro's recent publications reveals a strong focus on translating basic science discoveries into clinical applications. Her work spans multiple disciplines including neuro-oncology, cancer immunology, nanomedicine, epigenetics, and artificial intelligence. A common thread throughout her research is the development of targeted therapies that address specific molecular vulnerabilities in brain tumors, particularly focusing on IDH-mutant gliomas and pediatric high-grade gliomas. Her publications demonstrate increasing collaboration with interdisciplinary teams including engineers, computer scientists, and clinicians to develop comprehensive treatment approaches. Dr. Castro actively collaborates with numerous researchers, most notably with Dr. Pedro Lowenstein on oncolytic virus therapies and with Dr. Anna Schwendeman on nanodisc technology. Her work has attracted significant research funding for developing novel brain tumor treatments, particularly in the areas of targeted drug delivery systems and immunotherapies. She is involved in multiple translational research projects aiming to move laboratory discoveries into clinical trials for brain tumor patients. Her laboratory operates at the intersection of multiple research areas, with teams focused on nanomedicine development, viral vector engineering, AI applications in neurosurgery, and molecular characterization of brain tumors. The lab utilizes sophisticated mouse models of glioma and works closely with clinicians to ensure research is clinically relevant. Recent work has expanded into studying the tumor microenvironment and how immune cells interact with brain tumor cells, opening new possibilities for combination therapies.

Seth Parkerمشاهده پروفایل

استادیار

• Cancer Metabolism
• Nutrient Transporter Biology
• Childhood Leukemia
• +۶ مورد دیگر

Dr. Seth Parker is an Assistant Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia Faculty of Medicine . Based at BC Children’s Hospital, his research group deciphers how nutrient transporters and metabolic reprogramming drive diseases such as cancer, with a special focus on childhood leukemia. He combines biochemical assays, molecular biology, and cutting-edge mass-spectrometry platforms to reveal druggable metabolic vulnerabilities. Research Interests Transporter Biology: Discovery and functional characterization of solute carrier (SLC) transporters that dictate nutrient flux in diseased cells. Compartmentalized Metabolism: Development of organelle-specific metabolomics to understand how enzyme isoform localization provides a proliferative advantage to tumors. Pediatric Leukemia: Identification of selective metabolic dependencies in relapsed childhood leukemia and evaluation of transporter-targeted therapies as alternatives to systemic nutrient depletion. Research Output & Trends Across 2020-2024, Dr. Parker has co-authored multiple high-impact studies ( Nature, Cell, Nat Cancer, Cancer Discov ) that collectively map metabolic rewiring in pancreatic cancer, glioma, Ewing sarcoma, and leukemia. A consistent theme is the integration of metabolomics, proteomics, and in vivo models to translate metabolic findings into therapeutic strategies. Scientific Awards No specific awards were listed in the provided text. Training & Mentorship Dr. Parker actively recruits graduate students, post-doctoral fellows, and research associates. His lab website invites prospective trainees to inquire about opportunities in metabolomics, transporter biology, and pediatric cancer research. Labs & Teams The Parker Laboratory is located in the BC Children’s Hospital Research Institute, with access to core facilities for mass spectrometry, flow cytometry, and animal models, fostering collaborative networks across UBC and the BC Cancer Research Centre.

• Viral Oncology
• NF-kB Signaling
• Innate Antiviral Immunity
• +۴ مورد دیگر

Dr. Edward Harhaj is a Professor at the Department of Cell and Biological Systems within the Penn State College of Medicine , affiliated with the Penn State Cancer Institute (Mechanisms of Carcinogenesis program). His research focuses on the molecular mechanisms of viral-induced malignancy and innate antiviral immunity . Education: PhD in Microbiology and Immunology, Penn State College of Medicine (1999) Postdoctoral Training in Immunobiology, Howard Hughes Medical Institute (2001) MS and BA in Biology, Bucknell University (1994 and 1992) Research Interests: Dr. Harhaj investigates HTLV-1 (Human T-cell leukemia virus type 1) , which causes adult T-cell leukemia (ATL) and HAM/TSP. His lab explores how the viral protein Tax activates the NF-kB/Rel transcription factor family , critical for tumor cell survival. Additionally, he studies negative regulation of innate immune pathways like RIG-I-MAVS and cGAS-STING, aiming to prevent excessive inflammation during antiviral responses. Recent Research Trends: His work emphasizes autophagy and ubiquitin pathway components in Tax-mediated oncogenesis, as well as mitophagy and interferon signaling in innate immunity. Key subfields include signal transduction , transcription factor regulation , and immune homeostasis . Grants & Projects: Active NIH-funded projects (NIAID) include studies on TAX1BP1 , VEGFR2 regulation of HTLV-1 , and ZFAND6 in antiviral immunity (2021–2026). Past projects (2015–2024) address innate immune signaling and autoimmune pancreatitis. Laboratory Focus: The Harhaj lab employs multidisciplinary approaches to dissect virus-host interactions , oncogenic signaling , and innate immune regulation , with collaborations spanning molecular biology, virology, and immunology.

Kathleen C.F. Sheehanمشاهده پروفایل

استاد

• Cytokine Biology
• Interferons
• Tumor Necrosis Factor (TNF)
• +۷ مورد دیگر

Kathleen C.F. Sheehan, PhD is a Professor in the Department of Pathology and Immunology at Washington University in St. Louis (WUSM). She holds leadership roles as Director of the Hybridoma Center, Co-Head of the Immunomonitoring Laboratory (IML) within the Bursky Center for Human Immunology and Immunotherapy Programs (CHiiPs), and Director of the Immunoassays Group. Education: BS, University of Notre Dame (1980) PhD, St. Louis University School of Medicine (1986) Her research focuses on cytokine biology, particularly the role of interferons and tumor necrosis factor in immune diseases, cancer immunotherapy, and infectious disease mechanisms. She specializes in developing monoclonal antibodies (mAb) using Armenian hamster models and genetic immunization techniques for both research and clinical applications. Sheehan’s work includes high-dimensional analyses of immune cell populations during immune checkpoint therapy (ICT), combinatorial cancer treatment strategies, and immunoassay development. Her antibody-based therapies have demonstrated efficacy in murine tumor rejection models. Scientific Awards: Member, Alpha Sigma Nu honor society She oversees two shared resource facilities: the Hybridoma Center for mAb development and the IML for immunomonitoring in human/mouse models.

Cecelia C. Yatesمشاهده پروفایل

دانشیار

• Fibrosis
• Tissue Remodeling
• Extracellular Matrix
• +۴ مورد دیگر

Dr. Cecelia C. Yates is an Associate Professor in the Department of Nurse Anesthesia at the University of Pittsburgh's School of Nursing. She directs a cellular/molecular laboratory researching chemokine-matrix interactions in fibrosis (Systemic Sclerosis, Idiopathic Pulmonary Fibrosis) and develops small-molecule/cellular therapies for tissue remodeling. She teaches graduate Pathophysiology and undergraduate Anatomy & Physiology labs, mentors pre-doctoral/undergraduate researchers, and participates in the Undergraduate Research Mentorship Program (URMP). Her research explores: Chemokine/extracellular matrix dynamics in fibrotic diseases Genomic regulation of fibrosis progression Biomimetic therapeutics (e.g., FibroKine peptides) Stem cell applications in scar minimization Publications emphasize fibrosis mechanisms, wound healing, and therapeutic innovations, with recent focus on COVID-19/fibrosis convergence and macrophage polarization. Awarded: Prestigious Early Career Award NAI Senior Member recognition She secured a $250,000 CSL Behring grant (2020) for FibroKine development and a patent for anti-fibrotic technologies. Her lab collaborates nationally on projects like glaucoma fibrosis therapy and cardiac remodeling.

• Stem cell biology
• Tissue engineering
• Bioprinting
• +۳ مورد دیگر

Dr. Kerstin Schneeberger-Verjaal is an Assistant Professor at the Department of Clinical Sciences, Internal Medicine of Companion Animals, Faculty of Veterinary Medicine, Utrecht University. She also serves as a Scientific Advisor at Orgonex B.V. Her research focuses on stem cell biology and tissue engineering, particularly developing mini-livers from patient-derived stem cells to address organ shortages for transplantation. VenI grant recipient (2018) for liver research Co-developer of synthetic growth gel for large-scale liver cell culture Principal investigator in €1.4 million Horizon 2020 bioprinting project Her recent publications highlight advancements in bioprinting technology , hydrogel development , and organoid scalability . Key research collaborations include Dr. Bart Spee and European experts in the ORGANTRANS consortium. Scientific awards: 2018 NWO Veni grant 2018 WFIRM Young Investigator Award 2017 Aegean award (Tissue Engineering Conference) 2017 Best selected presentation at HEPRO symposium 2014 EMBO workshop attendance grant 2013 Best oral presentation (Dutch Stem Cell Meeting) In her ancillary role at Orgonex B.V., she contributes to commercial applications of organoid technology. Her work has generated multiple patents and translational grants for clinical implementation of synthetic growth gels.

Gürkan Bebekمشاهده پروفایل

استادیار

• Bioinformatics
• Systems Biology
• Precision Medicine
• +۴ مورد دیگر

Gürkan Bebek is an Assistant Professor at Case Western Reserve University with cross-departmental affiliations: Department of Nutrition, School of Medicine Center for Proteomics and Bioinformatics, School of Medicine Department of Computer and Data Sciences, Case School of Engineering Gürkan Bebek specializes in bioinformatics analysis of complex biological networks, focusing on precision medicine for cancer and systems biology of Alzheimer's disease. His research explores Shared mechanisms in COPD and lung cancer Causal regulatory network inference Functional subgraph mining in cancer Proteomic differences in Alzheimer's progression Notch signaling in glioma stem cells as reflected in his publications spanning 2007-2025. Key collaborative networks include Alzheimer's disease proteomics with Miyagi Lab Glioblastoma research with Yu/Man/Bao teams Breast cancer metastasis studies with Keri Lab Network biology methodologies with Chance/Koyutürk groups