Phyllis Fung-Yi Cheung

Dr. Phyllis Fung-Yi Cheung is a researcher at the German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, affiliated with University Hospital Essen. Her work focuses on spatiotemporal tumor heterogeneity and therapy-induced dynamics in the tumor microenvironment (TME), particularly in solid cancers like pancreatic and hepatocellular carcinoma.

Research Interests:

• Therapy-induced dynamics in tumor microenvironment
• Spatial multi-omic analysis of cancer-associated fibroblasts
• Translational applications for drug resistance in solid tumors

Publication Trends: Her research spans drug resistance mechanisms, cancer immunology, and TME interactions. Key areas include pancreatic cancer, hepatocellular carcinoma, fibroblast activation, and immune evasion strategies using progranulin and MHCI regulation.

Scientific Awards:

• AIO Science Award 2022

Labs & Collaborations: Leads the DKTK research group on spatiotemporal tumor heterogeneity, collaborating across institutions to integrate dynamic and spatial heterogeneity studies for precision oncology.