جست‌وجوی استاد و پژوهشگر

Harris H. Wangمشاهده پروفایل

دانشیار

• Systems Biology
• Synthetic Biology
• Genome Engineering
• +۱۷ مورد دیگر

Harris H. Wang is an Associate Professor in the Department of Systems Biology and Department of Pathology and Cell Biology at Columbia University's Vagelos College of Physicians and Surgeons, where he also serves as Interim Chair of Systems Biology. He is affiliated with the Center for Computational Biology and Bioinformatics (C2B2) and the Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS). B.S., Physics and Mathematics, MIT Ph.D., Biophysics, Harvard University Dr. Wang's research lies at the intersection of systems and synthetic biology, focusing on developing foundational technologies for genome engineering, microbiome manipulation, and synthetic genomics. His lab pioneers methods such as MAGE, MAGIC, CAST, and CAMII to enable high-throughput genetic manipulation, in situ microbiome engineering, and AI-driven microbial culturomics. Key research themes include understanding microbial community dynamics, engineering cellular memory systems, designing biocontained genetic circuits, and applying synthetic biology to human health challenges in personalized medicine and infectious disease. His recent publications reveal a strong trend in spatial and functional metagenomics, CRISPR-based microbiome editing, and synthetic biology tools for data storage and genetic stability. The articles span high-impact journals like Nature , Science , and Nature Biotechnology , reflecting his leadership in developing scalable, programmable biological systems. Scientific Awards: NIH Director’s Early Independence Award Forbes 30 Under 30 in Science Sloan Research Fellowship NSF CAREER Award ONR Young Investigator Award Burroughs Wellcome Fund PATH Award Schaefer Scholar Blavatnik National Award Vilcek Prize PECASE Dr. Wang has advised numerous PhD and postdoctoral researchers, many of whom have gone on to independent scientific careers. His lab is supported by major grants from NIH, NSF, DARPA, DOE, and foundations including the Bill & Melinda Gates Foundation and CZ Biohub NY. He is actively involved in educational initiatives, including organizing Columbia’s iGEM team and the Cold Spring Harbor Laboratory Synthetic Biology course. The Wang Lab is based at the Columbia University Irving Medical Center and is part of national consortia such as the Engineering Biology Research Consortium (EBRC) and the Genome Project-Write (GP-Write) initiative. The lab develops and applies cutting-edge technologies in automation, machine learning, and synthetic biology to engineer microbiomes for applications in medicine, global health, and climate change.

Ning Zhangمشاهده پروفایل

استادیار

• Plant Defense Mechanisms
• Genome Editing Technologies
• Crop Improvement
• +۳ مورد دیگر

Ning Zhang is an Assistant Professor in the Biology Department at James Madison University (JMU), joining in 2024. Her research focuses on enhancing crop resilience through molecular and biochemical studies of plant defense mechanisms against bacterial pathogens, alongside developing genome editing technologies for trait improvement. She holds a PhD in Horticulture and Crop Science from The Ohio State University (2016), an MS in Silviculture from Zhejiang Agriculture and Forestry University (2011), and a BS in Landscape Architecture from Shandong Agricultural University (2008). Research Interests: Dr. Zhang's lab investigates plant immunity pathways, CRISPR/Cas9 genome editing applications, and engineering crops for disease resistance. Her work integrates molecular biology, genetics, and biochemistry to tackle challenges posed by climate change and biotic/abiotic stresses. Recent Trends in Publications: Her articles concentrate on MAPK signaling pathways, NLR protein interactions, PP2C phosphatase regulation, and bacterial effector mechanisms in tomato and other crops. Key themes include immune system activation, pathogen recognition diversity, and transgenic plant development. Lab Information: The Zhang Lab at JMU is part of the Department of Biology, focusing on plant biotechnology solutions for agricultural sustainability. They collaborate on projects involving CRISPR-based gene editing and stress tolerance research.

• Microbiology
• Infectious Diseases
• Cell Biology
• +۷ مورد دیگر

Manuel R. Amieva is a Professor at Stanford University School of Medicine , holding joint appointments in Pediatrics - Infectious Diseases and Microbiology & Immunology . He is also a member of the Maternal & Child Health Research Institute (MCHRI) . His clinical practice at Stanford Medicine Children's Health focuses on pediatric infectious diseases. Education: Medical Education: Stanford University School of Medicine (1997) Fellowship: Stanford University Pediatric Infectious Disease Fellowship (2004) Internship & Residency: Stanford Health Care at Lucile Packard Children's Hospital (1998-1999) Dr. Amieva's research investigates host-pathogen interactions at epithelial barriers, with specific expertise in Helicobacter pylori , Listeria monocytogenes , Salmonella enterica , and Staphylococcus aureus . His lab develops innovative organoid culture systems with controlled polarity to study microbial colonization and oncogenic mechanisms. Key discoveries include: H. pylori's manipulation of epithelial junctions via the CagA protein Listeria's exploitation of cell extrusion sites for invasion Staphylococcus toxin interactions with adherens junctions Gastric stem cell activation by pathogens Recent publication trends show continued leadership in infectious disease mechanisms (2020-2025), with a focus on: Pathogen-specific epithelial breach strategies Organoid modeling of viral/bacterial interactions Redox-dependent host factor regulation Single-cell spatial transcriptomic analyses Multi-institutional educational frameworks His scientific collaborations span disciplines including: Gastric cancer genomics initiatives COVID-19 lung infection models Stem cell-microbe interactions Medical education reform projects Dr. Amieva maintains active clinical research while mentoring students in both the Microbiology & Immunology and Pediatrics programs. His lab at Stanford employs advanced 3D confocal microscopy and organ-on-a-chip technologies to visualize epithelial colonization dynamics.

• Pathogen Ecology
• Microbial Evolution
• Antibiotic Resistance
• +۴ مورد دیگر

Prof. Dr. Alex Hall is an Associate Professor at the Department of Environmental Systems Science and Head of the Institute of Integrative Biology at ETH Zürich , Switzerland. He holds a PhD from the University of Edinburgh (2008), followed by postdoctoral work at the University of Oxford and ETH Zürich, including prestigious SNSF Ambizione and Marie Curie Intra-European fellowships. Research Focus: The Hall lab investigates Microbial interactions in human microbiomes Antibiotic resistance evolution Horizontal gene transfer dynamics Computational and in vitro modeling of microbial communities Evolutionary medicine applications Scientific Contributions: His recent studies analyze probiotic treatments for Staphylococcus aureus decolonization, strain-specific ecological success in gut microbiomes, and CRISPR-Cas system roles in plasmid conflicts. The lab employs computational frameworks combined with experimental validations. Scientific Awards: SNSF Ambizione fellowship Marie Curie Intra-European fellowship He also serves on the SNSF PRIMA fellowship evaluation panel and the ETH Zürich Coordination Council Medicine .

Waldemar Kolanusمشاهده پروفایل

استاد

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +۴ مورد دیگر

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

Lucas Paoliمشاهده پروفایل

پژوهشگر

• Microbiome Research
• Microbial Immunity
• Ecological Genomics
• +۴ مورد دیگر

Lucas Paoli is a Researcher and Course Instructor at École Polytechnique Fédérale de Lausanne (EPFL), Switzerland. He leads the Paoli Lab (Microbiome Immunity and Ecology) within the Global Health Institute (GHI) under the School of Life Sciences (SV). His roles include scientific collaboration and teaching responsibilities in life sciences engineering. Paoli holds a PhD in Microbiome Research from ETH Zürich (2018-2023), an M.Phil. in Environmental Policy from the University of Cambridge (2017-2018), and an M.Sc. in Ecology and Evolution from École normale supérieure (2015-2017). Research Focus: His work bridges microbial immunity and ecology, investigating how microbes defend against viral infections across ecosystems like oceans and human microbiomes. Techniques include global-scale metagenomics and functional genomics to study immune strategies and ecological interactions. Key themes involve microbial community dynamics, viral defense mechanisms, and the impact of environmental factors on microbial immunity. Lab & Education: The Paoli Lab explores microbiome-immunity interactions with a focus on ecological contexts. Paoli supervises PhD students in Life Sciences Engineering. His research outputs span microbial ecology, metagenomic tool development, and marine microbiome studies. Contact: lucas.paoli@epfl.ch, AAB 1 39, +41 21 693 16 99.

C. Perry Chouمشاهده پروفایل

استاد

• biochemical engineering
• bioprocessing
• biomanufacturing
• +۷ مورد دیگر

C. Perry Chou is a full professor in the Chemical Engineering Department at the University of Waterloo, with a cross-appointment in Biology. He holds a BSc and MSc from National Taiwan University and a PhD from Rice University, all in Chemical Engineering. His research focuses on integrating biochemical, genetic, and metabolic engineering strategies to enhance biomanufacturing using microbial cell factories. Key areas include recombinant protein production, microbial biotechnology, and biofuel development. Education: PhD in Chemical Engineering, Rice University (1995) MSc in Chemical Engineering, National Taiwan University (1987) BSc in Chemical Engineering, National Taiwan University (1984) Research Interests: Dr. Chou’s work spans biochemical engineering, bioprocessing, and metabolic engineering. He develops strategies for microbial strain construction, fermentation optimization, and bioproduct purification. His research bridges fundamental biological sciences with applied engineering to advance biomanufacturing. Publications: His 90+ peer-reviewed articles highlight contributions to strain engineering, CRISPR-Cas9 tools, and microbial production of chemicals like 5-aminolevulinic acid and propionate. Recent trends emphasize nanomaterial applications (e.g., graphene oxide) and sustainable biofuel pathways. Awards: Canada Research Chair (Canada) 1000-talent Award (China) Advising & Grants: Dr. Chou actively mentors graduate students and contributes to editorial roles at journals like Biotechnology Advances and Scientific Reports . He teaches courses such as CHE 161 (Engineering Biology) and CHE 562 (Advanced Bioprocess Engineering). Labs/Teams: Collaborates with interdisciplinary teams to advance bioprocess development, though specific lab names are not explicitly mentioned in the text.

Michael Baymمشاهده پروفایل

دانشیار

• Microbial Evolutionary Genomics
• Antibiotic Resistance
• Computational Biology
• +۷ مورد دیگر

Dr. Michael Baym is an Associate Professor of Biomedical Informatics at Harvard Medical School with affiliate appointments in Microbiology and the Laboratory of Systems Pharmacology, and as an Associate Member of the Broad Institute. He leads the Baym Lab, which studies microbial evolutionary genomics and antibiotic resistance through a hybrid of experimental, computational, and theoretical approaches. His research focuses on: Antibiotic Resistance Evolution and practical interventions Mobile Genetic Elements (plasmids, phages, transposons) Computational Genomic Algorithms for big data analysis Synthetic Biology tools and technologies Key recent publications explore phage discovery systems , phylogenetic compression of microbial genomes, and RNA-guided gene drives in plasmids. His work is supported by multiple NIH/NIGMS and NSF grants including a MIRA award. Scientific honors include: Packard Fellowship (2018) Pew Biomedical Scholarship (2020) Sloan Research Fellowship (2020) A. Clifford Barger Excellence in Mentoring Award (2021) SSQBio Mentorship Award (2022) The lab actively trains PhD students and postdoctoral fellows with alumni occupying academic and industry positions globally. Current team members include researchers from interdisciplinary backgrounds working at the intersection of experiment, computation, and theory .

Jonathan Conwayمشاهده پروفایل

استادیار

• Plant-microbe interactions
• Biomolecular engineering
• Systems biology
• +۴ مورد دیگر

Jonathan Conway is an Assistant Professor in the Department of Chemical and Biological Engineering at Princeton University and an associated faculty member of the High Meadows Environmental Institute (HMEI). He leads the Conway Lab, which focuses on engineering plant-microbe interactions for applications in bioagriculture, bioenergy, and biochemical industries. Education: B.S. Chemical Engineering, University of Notre Dame (2011) M.S. Chemical Engineering, North Carolina State University (2013) Ph.D. Chemical Engineering, North Carolina State University (2017) Postdoctoral Fellow, University of North Carolina Chapel Hill & Howard Hughes Medical Institute (2017-2021) Research Interests: The Conway Lab develops genetic engineering approaches for non-model bacteria at plant-microbe interfaces. Key research areas include: chemical signaling between plants and microbes, microbiome impacts on plant immunity, environmental stress responses in agricultural systems, and enzymatic degradation of lignocellulosic biomass using thermophilic bacteria. The lab employs bacterial genetics, systems biology, and biomolecular engineering to create technologies for sustainable bioindustries. Publication Trends: Recent work demonstrates strong emphasis on molecular mechanisms of plant-microbe communication (2020-2024), enzyme characterization in biomass degradation (2024-2025), and development of synthetic microbial communities for climate resilience (2024). Earlier research focused on extremophile enzymology and metabolic engineering (2012-2019). Student Advising: Currently mentors 4 graduate students and 8 undergraduates. Alumni include 9 former advisees who graduated between 2022-2024. The lab actively recruits students through Princeton's Chemical Engineering graduate program and undergraduate research initiatives. Laboratory: The Conway Lab develops microfluidic systems for root microbiome studies and genetic tools for engineering plant-associated bacteria. Current projects include designing thermophilic microbial consortia for consolidated bioprocessing and characterizing bacterial immune evasion strategies.

Pamela D. Robertsمشاهده پروفایل

استاد

• Sustainable Disease Management
• Plant Pathology
• Integrated Pest Management
• +۳ مورد دیگر

Dr. Pamela D. Roberts is a Professor of Plant Pathology and State Extension Specialist for Vegetable Pathology at the University of Florida's Southwest Florida Research and Education Center (SWFREC) in Immokalee, FL. She holds a B.Sc. in Horticultural Sciences from Kansas State University, an M.S. in Plant Pathology from the University of Hawaii, and a Ph.D. in Plant Pathology from the University of Florida. Her research focuses on sustainable disease management in vegetables and specialty crops, emphasizing integrated management strategies for bacterial and fungal-like pathogens. She leads the Florida Extension Plant Disease Diagnostic Laboratory at SWFREC, offering diagnostic services and disease management recommendations. Her extension programs include educational outreach on plant diseases and field demonstrations of integrated management techniques. Dr. Roberts has received prestigious awards such as the UF/IFAS Jim App Team Award and the Dallas Townsend Distinguished Extension Award. She serves as Editor-in-Chief of the American Phytopathological Society journal Plant Health Progress . Her work spans disease diagnosis, epidemiology, and pathogen evolution, with a strong emphasis on crops like tomato, pepper, and citrus. Her research publications address topics such as Xanthomonas pathogen diversity, remote sensing for disease detection, and sustainable agricultural practices. She collaborates on projects involving molecular diagnostics, pest management strategies, and crop resilience. Ongoing efforts include combating bacterial spot diseases, whitefly-transmitted viruses, and citrus black spot.

Yousif Shamooمشاهده پروفایل

استاد

• Antibiotic Resistance
• Bacterial Evolution
• Biophysics
• +۳ مورد دیگر

Yousif Shamoo is the Ralph and Dorothy Looney Professor of BioSciences at Rice University, where he has been a faculty member since 1998. He previously served as Vice Provost for Research (2014-2022) and Director of the Institute of Biosciences and Bioengineering (2008-2014). He holds a Ph.D. in Molecular Biophysics and Biochemistry from Yale University (1988). His research focuses on combating multi-drug resistant bacteria through experimental evolution and biophysical approaches. Key interests include: Evolutionary trajectories of antibiotic resistance in pathogens like Enterococcus and Acinetobacter Biochemical basis of adaptation using microfluidics, genomics, and structural biology Discovery of novel antimicrobial strategies targeting cell membrane stress pathways Microbial interactions in spatially structured environments Publications emphasize antimicrobial resistance mechanisms, evolutionary biophysics, and microfluidic technology development. Recent work explores daptomycin resistance pathways ( LiaFSR ), membrane lipid signaling, and high-throughput evolution platforms. Awards & Honors: AAAS Fellow (2024) Ralph and Dorothy Looney Professorship (2020) George R. Brown Award for Excellence in Teaching (2015) George R. Brown Superior Teaching Award (4×, 2009 onward) ASM Distinguished Lecturer (2011-2013) He leads an active research group funded by NIH and DoD, advising 15+ graduate students. Current projects integrate synthetic biology with Streptomyces-derived drug discovery and microfluidic biosurveillance platforms.

Eduardo Rochaمشاهده پروفایل

استاد

• Microbial Evolutionary Genomics
• Genome Organization
• Mobile Genetic Elements
• +۱۳ مورد دیگر

Eduardo Rocha is a Professor and Head of the Microbial Evolutionary Genomics laboratory at the Institut Pasteur, within the Department of Genomes and Genetics. His research integrates bioinformatics, molecular evolution, and genomics to understand bacterial genome organization and dynamics, particularly focusing on mobile genetic elements and their role in adaptation and antibiotic resistance. His research interests include microbial evolutionary genomics, genome organization, horizontal gene transfer, mobile genetic elements (plasmids, phages, integrons), bacterial pathogen evolution, and computational biology. His work lies at the intersection of molecular evolution, population genetics, and molecular epidemiology, with strong translational implications for understanding antimicrobial resistance and infectious disease emergence. The recent publications highlight a consistent focus on mobile genetic elements, genome plasticity, and bacterial adaptation. Key themes include the role of integrons and CRISPR-Cas systems in bacterial immunity, plasmid-mediated spread of antibiotic resistance, phage-plasmid interactions, and the development of bioinformatics tools for microbial genomics. These works frequently appear in high-impact journals such as Science , Nature Microbiology , and PLoS Biology , reflecting significant contributions to the field. Eduardo Rocha leads multiple funded research projects, including ERC-2011-StG EVOMOBILOME, ANR Magisbac, and ANR SHAPE. He has developed and maintains several widely used bioinformatics software tools: IntegronFinder, MacSyFinder, PanACoTA, SatelliteFinder, CapsuleFinder, TXSScan, and others. He mentors a large team of PhD students, postdoctoral researchers, and engineers, and has supervised numerous former students who now hold independent research positions worldwide. Eduardo Rocha has received research funding from major agencies including the European Research Council (ERC) and the French National Research Agency (ANR). His work is central to the LabEx IBEID and the INCEPTION convergence program, where he serves on the steering committee, promoting interdisciplinary research in infectious disease emergence. His laboratory, part of the Genomes and Genetics department, actively contributes to microbial evolutionary genomics through both methodological development and biological discovery. The team participates in networks such as Phages.fr, GDR BIM, and GDR AIEM, reinforcing its collaborative and integrative approach.

Tessa Quaxمشاهده پروفایل

دانشیار

• Archaeal Virology
• Virus-Host Interactions
• Microbial Cell Biology
• +۳ مورد دیگر

Prof. dr. Tessa Quax is an Associate Professor at the Faculty of Science and Engineering, University of Groningen, leading research in Molecular Microbiology . Her work focuses on archaeal virology and virus-host interactions, supported by prestigious grants including an ERC Starting Grant (2022) and NWO Vidi Grant (2023). Key Research Areas: Archaeal virus entry/egress mechanisms Cell surface dynamics and motility Extreme environment microbiology Genetic tool development for archaea Recent publications in Nature Reviews Microbiology (2025) and Current Opinion in Microbiology (2024) highlight her work on viral host recognition and structural diversity. Her lab's 44 research outputs span archaeal cell biology, viral evolution, and ecological impacts of virus-induced lysis. Scientific Recognition: KNAW Beijerinck Premium (2022) KNAW Early Career Award (2021) Hector Research Career Development Award (2021) ERC Starting Grant (2022) As Chair of the International Society for Viruses of Microbes SAB and Speaker of the German Microbiology Society's Microbial Viruses group, she coordinates global research networks including a HFSP grant (2023) with Japan/Australia/USA collaborators. Her lab currently includes PhD candidate Zaloa Aguirre Sourrouille and multiple postdoctoral researchers.

Joseph Baileyمشاهده پروفایل

استاد

• Plant-animal interactions
• Evolutionary ecology
• Ecology
• +۲ مورد دیگر

Joseph Bailey is a Professor in the Department of Ecology & Evolutionary Biology at the University of Tennessee, Knoxville. His research focuses on evolutionary ecology, particularly how species interactions link genes to ecosystems, natural selection in community contexts, and scaling genetic processes across geographic and molecular resolutions. He holds a Ph.D. from Northern Arizona University (2003). Education: 2003 – Ph.D., Northern Arizona University Research interests include plant-animal interactions, evolutionary ecology, and the genetic underpinnings of community dynamics. His work integrates molecular, ecological, and evolutionary approaches across diverse systems, including native and invasive species interactions. He has published extensively on topics such as genetic structure of foundation species, plant-microbe interactions, and herbivore-induced ecosystem changes. Lab and Affiliations: His research group operates out of the Joseph Bailey Lab ( http://joebaileylab.com/ ). Publications reflect a focus on community genetics, indirect ecological interactions, and the genetic basis of species interactions.

Jos Ruytinxمشاهده پروفایل

استاد

• Mycorrhizal Symbiosis
• Fungal Genetics
• Zinc Homeostasis
• +۵ مورد دیگر

Jos Ruytinx is a faculty member in the Department of Bio-engineering Sciences at Vrije Universiteit Brussel (VUB), Belgium. His research focuses on plant-fungal interactions, particularly ectomycorrhizal symbiosis and metal homeostasis mechanisms. He actively supervises graduate students and serves on PhD committees, contributing significantly to the academic community at VUB. Dr. Ruytinx's research interests span several interconnected fields: Mycorrhizal symbiosis between plants and fungi Zinc and heavy metal homeostasis in ectomycorrhizal systems Molecular mechanisms of fungal adaptation to metal stress Transport physiology in plant-fungal symbiotic relationships Evolutionary aspects of ectomycorrhizal fungi Responses to ionizing radiation in plant-microbe systems His recent publications demonstrate a strong focus on understanding how ectomycorrhizal fungi like Laccaria bicolor and Suillus luteus interact with their plant hosts under metal stress conditions, particularly zinc. Through comparative transcriptomics and functional characterization of transporters, his work reveals genetic determinants of symbiotic compatibility and mechanisms of metal tolerance. This research has implications for phytoremediation and sustainable agriculture in contaminated soils. Dr. Ruytinx has received recognition for his work with an h-index of 17 and over 2151 citations. His research is supported by multiple grants including: FWOAL1080: Zinc homeostasis in ectomycorrhizal symbiosis: nutrition and beyond (2023-2026) FWOTM1079: Reactive oxygen species in ectomycorrhizal fungi: damage, signaling or both? (2021-2025) OZR4191: Bilateral cooperation for joint PhD VUB-UHasselt (2023-2027) HERC66: 3D-CELLMAP project (2024-2028) As an academic advisor, Dr. Ruytinx has supervised 7 students through their theses, including Master's and Doctoral candidates. His laboratory focuses on fungal genetics and plant-microbe interactions, with particular expertise in zinc transport mechanisms in ectomycorrhizal systems. He actively participates in public engagement activities, including field samplings and expert commentary on fungi as biofertilizers.