جست‌وجوی استاد و پژوهشگر

• Pulmonary vasculature
• Heart Failure
• Cardiopulmonary Immunology

Michael Yeager, PhD, serves as an Associate Clinical Professor in the School of Medicine at the University of Colorado Denver, focusing on cardiopulmonary pathophysiology with emphasis on pulmonary hypertension and heart failure mechanisms. He completed his PhD at the University of Colorado Health Sciences Center in 2002, establishing foundational expertise in vascular biology. His research program investigates immunological and molecular drivers of pulmonary vascular disease, particularly the roles of autoantibodies, fibrocytes, and inflammatory cascades in disease progression. Analysis of his 14 publications (2012-2015) reveals consistent exploration of biomarker discovery, vascular remodeling, and immune dysregulation across pediatric and adult pulmonary hypertension. Key methodological approaches include proteomics, animal modeling, and molecular interrogation of cellular stress responses, with significant translational implications for personalized therapeutic strategies. Professional recognitions include: Outstanding Faculty award from Tau Beta Pi (2019) Chancellor's Teaching Recognition Award from the University of Colorado (2016) Dr. Yeager maintains active clinical research collaborations at Children's Hospital Colorado while mentoring within the medical school curriculum. His work bridges basic science discovery with clinical application through ongoing investigations into endothelial dysfunction and inflammatory mediators. Affiliated with the Department of Medicine, he contributes to pulmonary vascular research initiatives and participates in professional societies including the American Thoracic Society, American Heart Association, and T21 Research Society.

Simon Schäferمشاهده پروفایل

استاد

• Neuroscience
• Developmental Biology
• Stem Cell Research
• +۴ مورد دیگر

Prof. Dr. Simon Schäfer leads the Schäfer Lab at the Technische Universität München , focusing on engineering advanced organoid systems to study human brain development, disease modeling, and repair mechanisms. His work bridges stem cell biology, gene editing, and bioengineering to develop personalized therapies for brain disorders. Stem Cell & Organoid Technology Neurodevelopmental Mechanisms Neurodegenerative Disease Models Gene Editing & Neuroimmune Interactions Translational Neuroscience Recent research emphasizes brain organoid development, microglia phenotypes, and neurodevelopmental timing anomalies in autism. His team’s work also explores zika virus interactions with glioblastoma stem cells and neuronal plasticity in psychiatric disorders. Scientific awards and funding include support from the Deutsche Forschungsgemeinschaft (DFG), Brain & Behavior Research Foundation (BBRF), and Munich Cluster for Systems Neurology (SyNergy). Collaborations span institutions like the TUM Center for Organoid Systems. Advises 6 students (2 PhD, 1 MSc, 3 associated) Labs include Schäfer Lab, COS@TranslaTUM Contact: simon.schafer@tum.de

Lars Engstrandمشاهده پروفایل

استاد

• Microbiome Research
• Women's Reproductive Health
• Gastroenterology
• +۷ مورد دیگر

Lars Engstrand is a Professor in infection control at Karolinska Institutet, heading the Translational Microbiome Research and Pandemic Preparedness group within the Department of Microbiology, Tumor and Cell Biology. His research spans multiple disciplines with a focus on translational microbiome research and pandemic preparedness. Engstrand's research interests center on understanding the human microbiome's role in health and disease, particularly in women's reproductive health and gastroenterology. His group has established multiple large-scale clinical studies including SweMaMi (Swedish Maternal Microbiome project), BASIC (associations between microbiota and preterm birth), VaMiGyn (Vaginal Microbiota in Gynaecological health), and several others investigating the vaginal microbiome's relationship to pregnancy outcomes, HPV infection, and cervical cancer. His team also conducts significant research on gut microbiome in inflammatory bowel disease and colorectal conditions through projects like PopCol and KOLBIBAKT. Analysis of Engstrand's most recent publications reveals a strong focus on the relationship between microbiome composition and women's health outcomes. His research consistently examines how vaginal, gut, and oral microbiomes influence pregnancy complications, preterm birth, HPV infection, and mental health during pregnancy. The work often employs large cohort studies with comprehensive sampling strategies across multiple body sites and time points, providing robust data for understanding microbiome dynamics in health and disease. Engstrand leads the Microbiome Exploration and Development for Intervention (MEDI) initiative and the National Pandemic Center (NPC) at Karolinska Institutet. The NPC conducted large-scale sequencing during the COVID-19 pandemic and has amassed over 1.5 million samples. His research group includes multiple specialized teams focusing on culturomics, bioinformatics, labcore operations, women's health research, and pandemic preparedness.

• Cancer Biology
• Gene Regulation
• Breast Cancer
• +۶ مورد دیگر

Dr. Thomas A. Hughes is an Associate Professor of Cancer Biology at the University of Leeds and Professor of Biosciences at York St John University. As a Group Leader at the Leeds Institute of Medical Research, he focuses on gene regulation, tumour microenvironment, and nanomedicine approaches to improve cancer outcomes. Specializes in breast cancer, colorectal cancer, and rare diseases Develops therapeutic strategies using microRNAs and biomarkers Collaborates with clinicians, engineers, and chemists for translational research His research integrates molecular pathology with clinical data through partnerships with Leeds NHS Trusts, aiming to identify novel biomarkers and targets for therapy. Recent work emphasizes cholesterol metabolism, oxysterol signaling, and nanomedicine-based drug delivery systems. Key contributions include: Over 80 peer-reviewed publications in cancer biology and molecular therapeutics Leadership in MSc programs in Molecular Medicine and Cancer Biology and Therapy Extensive experience in grant review, editorial work, and doctoral supervision Scientific awards include Fellowship of the Higher Education Academy. His lab has mentored 26 doctoral students and numerous alumni in academia, clinical practice, and industry.

Christina Leslieمشاهده پروفایل

استاد پژوهشی

• Computational Biology
• Systems Biology
• Machine Learning
• +۷ مورد دیگر

Dr. Christina Leslie is a Research Professor and Member of the Computational & Systems Biology Program at Memorial Sloan Kettering Cancer Center (MSK). She leads an active research laboratory focused on developing computational approaches to understand complex biological systems. Dr. Leslie earned her PhD from the University of California, Berkeley and has established herself as a leading computational biologist in cancer research and immunology. Computational & Systems Biology Program, Memorial Sloan Kettering Cancer Center Gerstner Sloan Kettering Graduate School of Biomedical Sciences Dr. Leslie's research focuses on developing novel computational methods to study cellular biological systems from a global and data-driven perspective. Her lab exploits diverse high-throughput functional and genomic data to understand molecular networks underlying fundamental cellular processes, including transcription regulation, pre-mRNA processing, signaling, and post-transcriptional gene silencing. Her algorithmic methods draw heavily on machine learning to build accurate predictive models from noisy and high-dimensional biological data. Key areas of interest include modeling cell-type specific transcriptional programs and dissecting co- and post-transcriptional regulation, particularly microRNA-mediated gene regulation. Analysis of Dr. Leslie's publication record over the last five years reveals a strong focus on computational approaches to cancer genomics, immunology, and epigenetics. Her work bridges multiple disciplines, with a particular emphasis on developing machine learning methods to interpret complex biological data. The publications demonstrate increasing sophistication in integrating multiple data types (genomic, transcriptomic, epigenomic) to understand cancer biology and immune responses. Recent work shows a growing emphasis on single-cell technologies and spatial analysis of tumor microenvironments. Introduction of string kernel methodology for SVM classification of biological sequences Development of algorithms for predictive modeling of gene regulation First systems-level analyses of competition between microRNAs and between target transcripts Dr. Leslie actively mentors numerous graduate students and research associates, with current lab members including Vianne Gao, Alireza Karbalaghareh, Erik Ladewig, and several others. Her lab has received significant research funding to support their work on computational approaches to cancer biology and immunology. The Leslie Lab maintains close collaborations with multiple experimental groups at MSK, facilitating the translation of computational insights into biological understanding. The Leslie Lab operates within the Computational & Systems Biology Program at MSK, with strong ties to both the research and clinical missions of the institution. The lab maintains state-of-the-art computational infrastructure for analyzing large-scale genomic and proteomic datasets and collaborates extensively with wet-lab researchers to validate computational predictions experimentally.

Jessica Rosenholmمشاهده پروفایل

استاد

• Drug Delivery Systems
• Nanomedicine
• Biomaterials Engineering
• +۶ مورد دیگر

Jessica Rosenholm is a Professor at the Faculty of Science and Engineering, Department of Pharmacy at Åbo Akademi University. Her research focuses on drug delivery systems, nanomedicine, and biomaterials engineering. She holds a D.Sc.(Tech.) and has authored over 200 publications. Key research areas include mesoporous silica nanoparticles, 3D bioprinting, and antimicrobial resistance solutions. Her work contributes to UN Sustainable Development Goals, particularly in advancing health technologies. Notable achievements include the Akzo Nobel Nordic Research Prize 2009 and the Knight, First Class, of the Order of the White Rose of Finland (2022). She leads projects like the MADNESS Centre of Excellence, exploring materials-driven solutions against antimicrobial resistance. Education: Doctor of Science (Technology) Research Interests: Nanoformulations, biomedical imaging, microfluidics, and tissue engineering. Recent articles highlight innovations in programmable nanocomposites for hearing loss treatment, microfluidic assembly of nanostructures, and 3D printing of drug delivery systems. Awards: ÅAU Chancellor’s Prize (2013), Forskarpriset ur Harry Elvings legat (2009) Grants: Projects funded by EU, Finnish Research Council, and Sigrid Jusélius Foundation. Labs/Teams: BioNanoMaterials group explores cutting-edge technologies like nanomedical agents and microfluidics. Current projects include the NAP4DIVE initiative for blood-brain barrier drug delivery.

Igor Jurisicaمشاهده پروفایل

استاد

• Data Science and Computational Biology
• Machine Learning
• Artificial Intelligence
• +۶ مورد دیگر

Igor Jurisica is a Professor at the University of Toronto and a Senior Scientist at the Krembil Research Institute’s Data Science Discovery Centre for Chronic Diseases. He also serves as Visiting Scientist at IBM CAS, Scientific Director of the World Community Grid, and Chief Scientist at the Creative Destruction Lab (Rotman School of Management). His research focuses on integrative computational biology, data mining, and AI-driven models for cancer mechanisms, drug discovery, and chronic disease management. Key affiliations include the Osteoarthritis Research Program, Schroeder Arthritis Institute, and leadership roles in open science initiatives like the World Community Grid, a global distributed computing platform with 810,000+ volunteers. Jurisica’s work bridges computational tools (e.g., NAViGaTOR visualization platform, MirDIP databases) and clinical applications, emphasizing explainable AI in healthcare. Research interests span proteomics, microRNA regulation, systems vaccinology, and multi-omics integration for disease stratification. Notable contributions include identifying prognostic signatures in cancer and osteoarthritis, machine learning models for drug repurposing, and sportomics analyses of athletic biomarkers. He has been recognized as a Thomson Reuters Highly Cited Researcher (2014-2016) and ranked among the Top 100 AI Leaders in Oncology (2023). His labs develop open-access tools like PathDIP, OsteoDIP, and miRAnno to advance translational research.

Pingfu Fuمشاهده پروفایل

استاد

• Survival analysis
• Clinical trials
• Cancer research
• +۴ مورد دیگر

Pingfu Fu, PhD, is a Professor in the Department of Population and Quantitative Health Sciences at Case Western Reserve University's School of Medicine. He is also a member of the Developmental Therapeutics Program at the Case Comprehensive Cancer Center. His expertise spans biostatistics, mathematics, and computer science, with a focus on cancer research and HIV/AIDS. Dr. Fu advises researchers on study design and statistical methodology for clinical and pre-clinical studies. He teaches courses in survival data analysis and clinical trials, and was recognized as 'Professor of the Year' in 2010 by the Department of Epidemiology and Biostatistics. Education: PhD in Biostatistics (Case Western Reserve University, 2001), MS in Statistics (Case Western Reserve University, 1996), MS in Mathematics (Xiangtan University, 1988), and BS in Mathematics (Jiangxi Normal University, 1984). His research interests include survival analysis, tree-based methods, clinical trials, and statistical applications in medical research. He has co-authored numerous peer-reviewed articles, focusing on cancer disparities, radiomics, and computational pathology. Professional memberships include the American Statistical Association, American Mathematical Society, and American Cancer Society. Dr. Fu holds editorial roles at Reviews on Recent Clinical Trials , Journal of Clinical Oncology , and Journal of the National Cancer Center . His work has addressed mathematical challenges in stochastic processes and resolved statistical issues in study design and tree-based models. Notable contributions include developing risk prediction models for cancer outcomes and advancing interdisciplinary collaborations across oncology, biostatistics, and computer science. His lab focuses on integrating computational methods with clinical data to improve patient outcomes.

• Machine Learning
• Computational Biology
• Bioinformatics
• +۴ مورد دیگر

Catherine Mooney is a Professor in the School of Computer Science at University College Dublin (UCD), leading the Life Science Data Analytics Group (LiSDA). Her research focuses on applying machine learning to healthcare challenges, including biomarker development, clinical decision support systems, and addressing ethical and technical barriers in healthcare AI. Education: BSc in [field unspecified] from Trinity College Dublin PhD in Computer Science from UCD Prof Dip University Teaching & Learning from UCD Research Interests: Machine Learning applications in healthcare Biomarker discovery for neurological and metabolic conditions Explainable AI for clinical decision support Promoting diversity and inclusion in STEM education Her work bridges computational methods with medical challenges, emphasizing ethical AI and translational research. Notable Awards: Best Paper Award in Applied Biosciences (2023) UCD Long-Service Award (2022) Best Poster Award at ITiCSE ’20 (2020) Her research has led to impactful tools like LiSDA’s clinical decision support systems for epilepsy and pregnancy care. She also advocates for gender diversity in computing, serving in leadership roles like Vice Principal for EDI in UCD’s College of Science (2022–2024).

• Biomaterials
• Tissue Engineering
• Regenerative Medicine
• +۵ مورد دیگر

João F. Mano is a Full Professor at the Department of Chemistry, University of Aveiro, and Director of the Doctoral Program on Biotechnology. He leads the COMPASS Research Group and serves as Vice-Director at CICECO - Aveiro Institute of Materials. His academic appointments include Invited Professor at University of Lorraine (France), Visiting Professor at KAIST (South Korea), and Adjunct Professor at Ajou University (South Korea). Education: PhD in Chemistry (1996, Technical University of Lisbon); D.Sc. in Tissue Engineering, Regenerative Medicine and Stem Cells (2012, University of Minho) Research Interests focus on Biomaterials for Regenerative Medicine , integrating Nanotechnology , Microtechnology , and Biofabrication . His group develops Bioinspired Materials using polymer chemistry, Decellularized Extracellular Matrix , and 3D Bioprinting to engineer Cell Microenvironments for therapeutic applications. Recent Publications highlight advancements in Human-Derived Hydrogels , Photopolymerizable Scaffolds , Magneto-Responsive Biomaterials , and Programmable Bioinks . Trends show emphasis on Organ-on-a-Chip integration, Smart Living Materials , and Green Bioprinting methodologies. Scientific Awards include: European Research Council Advanced Grants (2015, 2020) Fellow at IUPAC, European Academy of Sciences, and American Institute of Medical and Biological Engineering ERC Proof of Concept Grants Doctor Honoris Causa from University of Lorraine and Utrecht UNESCO Chair on Biomaterials George Winter Award (European Society for Biomaterials) Supervisions & Collaborations encompass 74+ MSc, 26+ PhD students, and 40+ postdocs. He co-founded METATISSUE and CELLULARIS Biomodels , and serves as Editor-in-Chief of Materials Today Bio .

J. Christopher Loveمشاهده پروفایل

استاد

• Nano-based drugs
• Precision medicine
• Immunology
• +۳ مورد دیگر

J. Christopher Love is the Raymond A. (1921) and Helen E. St. Laurent Professor of Chemical Engineering at MIT, with affiliations to the Koch Institute for Integrative Cancer Research, Broad Institute, and Ragon Institute. He earned a BS in Chemistry from the University of Virginia and a PhD in Physical Chemistry from Harvard University under George Whitesides, followed by postdoctoral work under Hidde Ploegh at Harvard Medical School. His research focuses on single-cell analysis, precision medicine, and biomanufacturing. The Love Lab develops technologies for drug discovery, vaccine development, and equitable biologic medicine production. Notable successes include pioneering single-cell analysis platforms, advancing metastatic cancer diagnostics via liquid biopsies, and engineering yeast-based vaccine manufacturing. Recent articles highlight innovations in liquid biopsy sensitivity, AI-driven ECG diagnostics, and CAR T-cell therapies. Awards include the Keck Young Scholar (2009), Dana Scholar (2009), and Camille Dreyfus Teacher-Scholar. He co-founded OneCyte, HoneyComb, and Sunflower Therapeutics, and advises multiple biotech companies. His lab emphasizes translational research, integrating chemical and biological engineering principles to address global healthcare challenges. Current work explores manufacturability-by-design for vaccines, tumor immunology, and mucosal vaccine delivery systems.

• RNA Therapeutics
• MicroRNA Research
• Molecular Biology
• +۲ مورد دیگر

Jennifer Broderick is a Lecturer at the RNA Therapeutics Institute within UMass Chan Medical School in Worcester, MA. Her academic journey includes a BA from the University of Wisconsin School of Medicine and Public Health, a BS in Molecular Biology from the University of Wisconsin-Madison, and a PhD in Philosophy from the University of Massachusetts Medical School. Her research focuses on RNA therapeutics, microRNA function, and molecular biology mechanisms. Key areas include: RNA interference and silencing pathways MicroRNA quantification and therapeutic applications Gene regulation through splicing mechanisms Protein-RNA interactions in mammalian systems Her publications show consistent focus on RNA biology, with recent work advancing therapeutic RNA design and microRNA quantification techniques. Earlier research explored tau protein splicing and RNA silencing mechanisms. Dr. Broderick collaborates with prominent researchers including Phillip Zamore and Guangping Gao, and is part of the RNA Therapeutics Institute research community.

Daniel Catchpooleمشاهده پروفایل

استاد

• Childhood Cancer Research
• Genomics
• Biomedical Data Science
• +۶ مورد دیگر

Professor Daniel Catchpoole serves as Deputy Head of School (Research) at the School of Computer Science, University of Technology Sydney (UTS), holding dual appointments at UTS and The Children's Hospital at Westmead. With over 20 years of research experience, he bridges computational sciences and pediatric cancer research through the Biomedical Data Science Lab in the Australian Artificial Intelligence Institute. His work integrates data analytics, artificial intelligence, and software development with molecular cancer biology to transform pediatric cancer treatment pathways. PhD in Cancer Cell Biology, University of New South Wales (1991-1995) Founding Fellow, Royal College of Pathologists Australasia (2010-present) Head, Children's Hospital at Westmead Tumour Bank (2001-present) Professor Catchpoole's research focuses on translational applications of genomics in childhood cancers, particularly acute lymphoblastic leukemia and neuroblastoma. His work combines high-throughput genomic technologies with advanced computational analysis to develop systems biology approaches for cancer patient assessment. Recent projects explore virtual reality applications for complex genomic data visualization and copper chelation therapies to enhance neuroblastoma immunotherapy. His research has received significant funding from Cancer Institute NSW, Sony Foundation, ARC, and NHMRC. His publication record spans biomedical data science, cancer genomics, and virtual reality applications in oncology. Recent work demonstrates leadership in 3D latent diffusion models for tumor segmentation, biobank economics, and innovative immunotherapies. His research consistently addresses the critical need for actionable knowledge from complex multidimensional biomedical data. Editorial Board Member, Cancers (2023) Associate Editor, Innovations in Digital Health, Diagnostics and Biomarkers (2019) Founding member and first President, Australasian Biospecimens Network Association Professor Catchpoole has supervised 17 Honours students (including 6 First Class Honours), 3 MSc students, and 12 PhD candidates across multiple institutions, with 6 current PhD students. His collaborative research bridges UTS's Faculty of Engineering and IT with The Children's Cancer Research Unit at The Children's Hospital at Westmead. Significant research funding includes Cancer Institute NSW grants, Sony Foundation VR projects, and ARC Discovery Projects focused on genomic data analysis and clinical decision support systems. His leadership extends to building frameworks for translational research, managing biobanks and clinical data linkages, and navigating governance requirements for cancer research. The Tumour Bank at Kids Research, CCRU, represents his long-standing commitment to pediatric cancer infrastructure development.

Alexander Nikitinمشاهده پروفایل

استاد

• Cancer Biology
• Molecular Pathology
• Stem Cell Research
• +۳ مورد دیگر

Alexander Nikitin is a Professor of Pathology at Cornell University's College of Veterinary Medicine, Department of Biomedical Sciences. His research focuses on molecular mechanisms linking tissue homeostasis to cancer development using autochthonous mouse models. Key Affiliation: Cornell University, Ithaca, NY Research Niche: Cancer-prone stem cell niches in female reproductive tract and prostate Research Interests Dr. Nikitin investigates how aberrations in p53/miR-34/MET and Rb networks drive malignant transformation of adult stem cells. His work includes: Identification of ovarian surface epithelium stem cell niche Technology-oriented cross-disciplinary collaborations Characterization of cancer initiation mechanisms in reproductive tissues Article Trends His publications span 2003–2025, emphasizing: Mouse models for epithelial cancers Role of tumor suppressor genes (p53, Rb) in cancer miR-34 family's tumor suppression functions Stem cell niche mapping in reproductive tract cancers Genetic drivers of high-grade serous carcinomas Translational research applications Lab Members Current lab personnel include: Andrea Flesken-Nikitin (Assistant Research Professor) Christopher Ashe (Research Support Specialist) Technicians and student researchers

Peter Barnesمشاهده پروفایل

استاد

• Respiratory Science
• Asthma
• COPD
• +۵ مورد دیگر

Professor Sir Peter Barnes is a leading figure in respiratory science at Imperial College London's National Heart and Lung Institute (NHLI) . As Professor of Thoracic Medicine , his work focuses on Asthma, COPD, and cellular senescence in lung disease , with over four decades of contributions to understanding inflammatory pathways and therapeutic innovations. Research Interests Mechanisms of chronic airway inflammation in Asthma and COPD Cellular senescence in lung aging and disease progression MicroRNA transfer via extracellular vesicles in COPD pathogenesis Targeted drug delivery for respiratory conditions Global health implications of lung disease Recent Publications highlight trends in: MicroRNA regulation of senescence and inflammation Extracellular vesicle dynamics in lung disease Biologics and corticosteroid efficacy in respiratory conditions Environmental factors influencing COPD and asthma Scientific Recognition Knighthood (2023) for services to respiratory science Fellow of the Royal Society (FRS) and Academy of Medical Sciences (FMedSci) Collaborative Leadership at NHLI has mentored numerous postdocs and researchers. His work intersects with global initiatives like GOLD (Global Initiative for COPD) , influencing clinical guidelines and public health policy.