معرفی
Alexander Nikitin is a Professor of Pathology at Cornell University's College of Veterinary Medicine, Department of Biomedical Sciences. His research focuses on molecular mechanisms linking tissue homeostasis to cancer development using autochthonous mouse models.
- Key Affiliation: Cornell University, Ithaca, NY
- Research Niche: Cancer-prone stem cell niches in female reproductive tract and prostate
Research Interests
Dr. Nikitin investigates how aberrations in p53/miR-34/MET and Rb networks drive malignant transformation of adult stem cells. His work includes:
- Identification of ovarian surface epithelium stem cell niche
- Technology-oriented cross-disciplinary collaborations
- Characterization of cancer initiation mechanisms in reproductive tissues
Article Trends
His publications span 2003–2025, emphasizing:
- Mouse models for epithelial cancers
- Role of tumor suppressor genes (p53, Rb) in cancer
- miR-34 family's tumor suppression functions
- Stem cell niche mapping in reproductive tract cancers
- Genetic drivers of high-grade serous carcinomas
- Translational research applications
Lab Members
Current lab personnel include:
- Andrea Flesken-Nikitin (Assistant Research Professor)
- Christopher Ashe (Research Support Specialist)
- Technicians and student researchers
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