Dr. Lukas Frey is a Researcher at ETH Zurich, affiliated with the Chair of Physical Chemistry and the Institute of Molecular Physical Sciences (IMPS). His work focuses on biophysical studies of membrane proteins, lipid dynamics, and protein aggregation mechanisms. Key research areas include structural biology of ion channels, NMR spectroscopy of membrane proteins in nanodiscs, and the role of lipid environments in modulating protein dynamics. Frey employs advanced techniques like mass photometry and solid-state NMR to investigate molecular mechanisms in biological systems. His recent studies address amyloid fibril formation, pH-dependent α-synuclein polymorphism, and cholesterol-mediated modulation of membrane protein behavior. Based at the HCI F 228 facility in Zurich, Frey collaborates on projects involving lipid bilayer environments, ion channel function, and the structural basis of protein aggregation. His email is lukas.frey@phys.chem.ethz.ch, and he holds an ORCID identifier 0000-0002-1052-1104. Research contributions span from fundamental biophysical insights to methodological advancements in membrane protein analysis.
Dr. Yi Shen is a Senior Lecturer at the School of Chemical and Biomolecular Engineering, The University of Sydney, and Chair of RACI Women in Chemistry. She is also affiliated with multiple research institutes including Sydney Institute of Agriculture, Sydney Southeast Asia Centre, The Centre for Drug Discovery Innovation, and The University of Sydney Nano Institute. PhD in Soft Materials from ETH Zurich Postdoctoral research at University of Cambridge and Harvard University Her research focuses on protein phase behavior and functional biomaterials development, utilizing soft matter approaches and microfluidic techniques to address challenges in neurodegenerative diseases, sustainable materials, and biomedical engineering. She has published extensively in top journals like Nature Nanotechnology and PNAS, with a particular emphasis on: Protein liquid-liquid phase separation mechanisms Biomaterials from protein nanofibrils Microfluidic manipulation of biological systems Biodegradable bioplastics development Shear force effects on biomolecular systems Pathological protein aggregation dynamics Key scientific achievements include: 2022 ARC DECRA Fellowship 2022 Sydney Nano Frontier award 2018 ETH Zurich Spark Award (for Fe delivery system invention) 2012 Princeton Grand Challenges Program 2 patents pending 2 Nature Nanotechnology cover articles As an educator, she coordinates CHNG2802 Chemical Engineering Modelling and Analysis, co-teaches CHNG3804 Biochemical Engineering and CHNG5605 Bio-products: Laboratory to Marketplace, and guest lectures across biomedical and nanotechnology programs. Her lab actively collaborates with institutions in Switzerland (ETH Zurich), UK (Cambridge), and US (Harvard, Princeton), focusing on transforming biomolecular understanding into real-world applications in health, industry, and environmental sustainability.
Aditi Das is a Full Professor in the School of Chemistry and Biochemistry at the Georgia Institute of Technology, College of Sciences. She leads the Das Laboratory, which focuses on the biochemistry and chemical biology of lipids, particularly studying cytochrome P450 enzymes and their role in lipid metabolism, endocannabinoid systems, and inflammatory pathways. Her educational background includes: B.Sc. in Chemistry from St. Stephen's College M.Sc. in Chemistry from Indian Institute of Technology, Kanpur (I.I.T) Ph.D. in Chemistry from Princeton University Postdoctoral research at Northwestern University (NSF-NSEC fellow) and Beckman Institute for Advanced Science and Technology, University of Illinois UC Professor Das's research interests center around understanding the physiological role of lipids in sustaining homeostasis and their implications in disease states such as neurodegenerative disorders, cancer, and cardiovascular diseases. Her laboratory specializes in: Enzymology of cytochrome P450s, particularly CYP2J2 epoxygenase Metabolism of ω-3 and ω-6 fatty acids and their derivatives Minor cannabinoid metabolism by cytochrome P450 enzymes Discovery of novel anti-inflammatory lipid metabolites and endocannabinoids Mechanistic studies of membrane proteins using nanodisc technology Her work bridges biochemistry, chemical biology, and pharmacology to uncover novel therapeutic targets related to lipid signaling pathways. Analysis of Professor Das's recent publications (2023-2025) reveals a strong focus on cannabinoid metabolism by cytochrome P450 enzymes, with particular emphasis on how these metabolic processes generate bioactive compounds that interact with the endocannabinoid system. Her research increasingly explores the therapeutic potential of omega-3 derived endocannabinoid epoxides in inflammatory and neurodegenerative conditions. The use of nanodisc technology for studying membrane proteins in near-native environments remains a consistent methodological thread throughout her work, enabling detailed mechanistic insights into enzyme function. Professor Das has received numerous prestigious awards recognizing her research excellence and teaching: 2024 NIH Outstanding Researcher Award (MIRA R35) for established investigators 2024 Vasser Woolley Faculty Fellowship 2023 Plenary Lecture at the International Society of the Study of Xenobiotics (ISSX) 2021 E.L.R. Stokstad Award 2019-2021 List of Teachers Ranked as Excellent 2019 Eicosanoid Research Foundation Young Investigator Award 2019 Zoetis Research Excellence Award 2019 Mary Swartz Rose Young Investigator Award 2015 National Scientist Development Award from the American Heart Association 2022 El Sohly Award from the American Chemical Society Professor Das actively mentors a diverse group of students and postdoctoral researchers, with several former lab members now holding faculty positions or working at prestigious institutions. Her laboratory has secured significant funding from NIH, NSF, and other sources to support research on lipid metabolism, cannabinoid pharmacology, and membrane protein biochemistry. Notable grants include an NIH R35 Outstanding Investigator Award (MIRA), an NIH R21 grant from NIDA, and multiple collaborative grants with other research groups. The Das Laboratory operates within the Petit Institute of Bioengineering and Biosciences (IBB) at Georgia Tech, utilizing state-of-the-art facilities for biochemical and biophysical studies. The lab specializes in nanodisc technology to study membrane proteins in near-native environments, with particular expertise in cytochrome P450 enzymes and their interactions with lipid substrates. Recent work has expanded into collaborative projects involving lipidomics, structural biology, and translational applications of lipid signaling research.
Chris Chipot is a Researcher and former Research Director at the CNRS, affiliated with the University of Lorraine. He holds adjunct faculty positions at the University of Illinois (Department of Physics) and the University of Chicago (Department of Biochemistry and Molecular Biology). He directs an Associate International Laboratory between CNRS and the University of Illinois at Urbana-Champaign. His expertise spans theoretical chemistry, molecular dynamics simulations, and membrane protein studies. Education: PhD in Theoretical Chemistry (1994, Henri Poincaré University, France) with a fellowship from Roussel Uclaf Institute. Habilitation (2000, University of Lorraine). Research Interests: Focuses on protein-ligand binding free energies, membrane protein dynamics, computational methods for molecular simulations, and biophysical techniques. His work integrates theoretical approaches with experimental validations, particularly in drug design and membrane biology. Publications: Recent articles highlight advancements in free-energy calculations, membrane protein dynamics, and scalable molecular dynamics software (NAMD). His research bridges computational and experimental biophysics, addressing challenges in structural biology and drug discovery. Awards: Fellowship from the Roussel Uclaf Institute during PhD studies. Advising & Grants: Leads collaborative projects via the CNRS-UIUC lab, fostering international research partnerships. His work has been supported by institutional and international grants, though specific funding details are not detailed here. Labs/Teams: Directs the CNRS-UIUC Associate International Laboratory, promoting interdisciplinary research in computational biophysics and membrane protein studies.
Professor Thomas Meier is a Visiting Professor at the Department of Life Sciences, Imperial College London (since 2015), and Director of the Centre for Structural Biology (2017–2021). He leads research on ATP synthase structure, drug targets for tuberculosis, and molecular mechanisms of disease. Previously, he was a Group Leader at the Max-Planck-Institute of Biophysics (2006–2015) and ETH Zurich's Institute of Microbiology. His work combines structural biology (X-ray crystallography, electron microscopy) with biochemical studies. Education: Dr. sc. nat. (2002) and Dipl. sc. nat. (1998) from ETH Zurich. Awards include the Wellcome Trust Investigator (2015–present). Research focuses on ATP synthase's role in energy conversion, drug development, and structural biology. His lab includes postdocs and students like Lisa Uhrig and Anthony Cheuk. Key affiliations: Centre for Structural Biology, Membrane Biology Group, and Bacterial Pathogenesis studies. Languages: German, English, French (fluent), Latin (read/write). Publications span structural biology, planetary science, and drug discovery. His work on ATP synthase inhibitors for TB has clinical implications, while astrophysical studies explore planetary formation via giant impacts.
Prof. Veronika Somoza is a leading academic in Nutritional Systems Biology, currently affiliated with the University of Vienna and Technical University of Munich (TUM). She holds a professorship in Molecular Food Science and has led key research groups such as the Institute of Physiological Chemistry and the Christian Doppler Laboratory for Bioactive Aromatics. Her career includes roles at institutions like the German Research Institute for Food Chemistry (Garching) and the University of Wisconsin-Madison. Education: Diplom (Justus Liebig University Giessen, 1991), PhD (University of Vienna, 1995), Habilitation (Kiel University, 2002) Research Focus: Bioactive food compounds, flavor chemistry, taste receptor signaling, and gastrointestinal physiology Her work bridges food science and human health, particularly in understanding how food ingredients influence digestion, inflammation, and disease. Notable contributions include discoveries on bitter peptide effects on gastric acid secretion and flavor perception modulation. Awards: FEMA Excellence in Flavor Science (2016), ACS AGFD Fellow (2020), Hans Adolf Krebs Prize (2004) Prof. Somoza has pioneered methodologies in atomic force microscopy for foodborne virus detection and developed bitterness-masking compounds for pharmaceuticals. Her interdisciplinary approach integrates nanobiophysics with nutrition to advance functional food design and clinical applications.
Prof. Dr. Markus Meissner is a Professor at the Faculty of Veterinary Medicine, Ludwig Maximilian University of Munich, leading the Chair of Experimental Parasitology. His research focuses on the molecular mechanisms of host cell invasion and modulation by Apicomplexan parasites, particularly Toxoplasma gondii and Plasmodium species. Research Group: Meissner Laboratory Location: Lena-Christ-Str. 48, 82152 Planegg-Martinsried Contact: markus.meissner@lmu.de His work investigates the secretory pathway of parasites, vesicular trafficking systems, and essential genes involved in host cell invasion and intracellular development. Toxoplasma gondii serves as a model organism for studying Apicomplexan biology, including nuclear division and CRMP complex functionality. Recent publications highlight the role of Rab GTPases in protein trafficking, chromatin remodeling in Plasmodium, and actin dynamics in parasite motility. Articles span topics such as egress factors, Golgi pathways, and lineage-specific organelle emergence, reflecting a multidisciplinary approach combining molecular biology, cell biology, and evolutionary analysis. The Meissner Lab includes PhD students (Peipei Qin, Yuan Song, Ella Schadt, Vitoria Catschor dos Santos) and postdocs (Dr. Wei Li, Dr. Miriam Rafajlovic). Research is conducted in Lena-Christ-Str. 48, Planegg-Martinsried, with a focus on experimental systems for studying parasite mechanisms.
Ana Damjanovic is an Assistant Research Professor in the Thomas C. Jenkins Department of Biophysics at Johns Hopkins University (JHU), affiliated with the Zanvyl Krieger School of Arts & Sciences. Her research focuses on ion channels, protein and membrane electrostatics, and computational biophysics. She holds a Ph.D. in Physics from the University of Illinois at Urbana-Champaign, where she studied quantum physics of photosynthetic light harvesting under Prof. Klaus Schulten. Subsequent postdoctoral research included work on photosynthesis with Prof. Graham Fleming at UC Berkeley, and molecular dynamics studies of protein ionization at JHU. Her current lab investigates ion channel mechanisms, protonation dynamics, and electrostatic effects in biological systems using advanced computational tools. Group members include graduate student Nauman Sultan (co-supervised with NIH's Bernard Brooks) and undergraduates Marianne Ri and Vivek Booshan. Past advisees include Ada Chen (now a NIH postdoc) and Maggie Li. Key research contributions include developing pH replica exchange methods, protein pKa prediction using machine learning, and structural-functional studies of voltage-gated sodium channels. Her work has been published in high-impact journals like Proceedings of the National Academy of Sciences and Biophysical Journal . Lab affiliations include the Computational Biophysics Group at JHU, with access to cutting-edge simulation techniques and experimental validation platforms. Ongoing projects explore ion channel selectivity, membrane protein dynamics, and computational modeling of protonation-dependent phenomena.
Dr. Igor V. Pivkin is a Full Professor at the Institute of Computing within the Faculty of Informatics at the Università della Svizzera italiana (USI) in Lugano, Switzerland. His academic journey includes degrees from Novosibirsk State University (B.Sc./M.Sc. Mathematics), Brown University (M.Sc. Computer Science and Ph.D. Applied Mathematics), and postdoctoral research at MIT's Department of Materials Science and Engineering. His research focuses on multiscale/multiphysics modeling , numerical methods , and large-scale simulations of biological and physical systems. Key areas include biophysics, cellular/molecular biomechanics, stochastic modeling, and coarse-grained molecular simulations. He leverages high-performance computing (HPC) and particle-based methods to address complex biological phenomena. His work spans diverse applications, from understanding cellular mechanosensitivity and biofilm engineering to modeling cancer cell behavior and red blood cell dynamics in the spleen. His contributions bridge computational science, biotechnology, and biomedical research. He has published extensively in top-tier journals, with recent work advancing automated biofilm analysis, deep learning for microbial classification, and systems biology approaches to metal bioleaching. His lab collaborates on interdisciplinary projects, emphasizing computational innovation for real-world biological challenges.
Celeste Sagui is a Professor in the Department of Physics at North Carolina State University (NC State), affiliated with the College of Sciences. She holds additional roles as a faculty affiliate in Genomics Sciences at NC State and is a member of the Center for High Performance Simulation. Her research focuses on computational biophysics, biomolecular simulations, and free energy methods applied to nucleic acid structures, protein dynamics, and nanotechnology systems. She has contributed to the AMBER simulation package development, co-authoring versions from 10 to 14. Education: Doctorate in Physics, University of Toronto (1995) Licentiate degree, National University of San Luis, Argentina Research Interests: Sagui’s work explores DNA/RNA structure and phase transitions, electrostatic interactions, and methodologies for large-scale molecular simulations. Recent studies include nucleic acid hairpin instabilities linked to neurodegenerative diseases, polyglutamine aggregation mechanisms, and novel DNA motifs like the eGZ structure in Z-DNA. She employs quantum chemistry, density functional theory, and phase-field models to investigate systems ranging from biomolecules to nanomaterials. Publications: Her recent work emphasizes nucleic acid dynamics, free energy landscapes, and computational methods for studying diseases such as Friedreich’s ataxia and polyglutamine disorders. Key contributions include advancements in laser-driven simulations and infrared spectroscopy analysis of protein structures. Labs/Teams: Active in the Center for High Performance Simulation, focusing on high-throughput computational modeling and collaborative software development for biomolecular research.
Simon Sharpe is a Professor in the Department of Biochemistry at the University of Toronto and a Senior Scientist at The Hospital for Sick Children. His research focuses on the structural and dynamic properties of self-assembling proteins, particularly those involved in degenerative diseases, elastomeric proteins, and biological phase separation. The Sharpe Lab utilizes advanced biophysical techniques such as NMR spectroscopy, X-ray scattering, and electron microscopy to investigate these phenomena. BSc: Memorial University of Newfoundland (Cell Biology and Biochemistry, 1997) PhD: University of Western Ontario (Biochemistry, 2002) Postdoctoral Training: NIH (Solid-State NMR, 2002-2006) Research interests include: Protein self-assembly mechanisms Amyloid formation in neurodegenerative diseases Elastin and resilin biophysics Lipid-protein interactions Biological phase separation Structure-function relationships Lab members include Research Associate Dr. Sean Reichheld and PhD students James Otis, Asal Nady, and Robert Lu. The lab has dedicated access to 600 and 700 MHz NMR spectrometers and collaborates with SickKids facilities including the SBC Facility and Imaging Facility. Scientific awards: Canada Research Chair (2006-2016) Ontario Early Researcher Award (2010) Dr. Sharpe has taught courses including BCH374Y1 (Research Project in Biochemistry) and BCH425H (Structural Biology: Principles and Practice). His recent publications examine topics ranging from serum amyloid A structure to bacterial phase separation defenses, with methodologies combining solid-state NMR, fluorescence microscopy, and computational approaches.
James C. Gumbart is an Adjunct Professor in the School of Physics at Georgia Institute of Technology, with additional affiliation to the School of Chemistry and the Institute for Bioengineering and Bioscience . His research leverages molecular dynamics simulations to decode the atomic-level mechanisms of bacterial proteins and cellular structures. B.S., Physics and Mathematics, Western Illinois University, 2003 Ph.D., Physics, University of Illinois at Urbana Champaign, 2009 Dr. Gumbart's work bridges computational biophysics and biochemistry to understand: Mechanisms of bacterial membrane protein insertion and nutrient import Structural dynamics of cell wall mechanics SARS-CoV-2 spike protein interactions with ACE2 Free-energy calculations for protein-ligand binding Applications of machine learning in biomolecular simulations His publications reflect trends in membrane protein biophysics , viral dynamics , and computational drug design , with a strong emphasis on interdisciplinary techniques. Awards include multiple fellowships and grants from NSF , DOE , and NIAID . He has mentored numerous PhD students, including Zijian Zhang , David Ryoo , and Andrew Pang , whose work has advanced understanding of bacterial systems and viral proteins. The Gumbart Lab integrates high-powered supercomputing and advanced software to model biomolecular processes, fostering collaborations with institutions like the National Institutes of Health and Argonne National Laboratory .
Kathrin Lang is a Full Professor at the Department of Chemistry and Applied Biosciences, ETH Zurich, and Head of the Organic Chemistry Laboratory. Her research focuses on chemical biology, particularly the development of tools for genetic code expansion to incorporate non-canonical amino acids into proteins and advance bioorthogonal chemistries for studying biological processes. Keywords: Genetic Code Expansion, Bioorthogonal Chemistry, Protein Engineering, Ubiquitylation Networks, Post-Translational Modifications. Lang’s work emphasizes proximity-triggered crosslinking reactions, bioorthogonal labeling, and in vivo chemistries to address challenges in protein interaction mapping and structural elucidation. Her group’s recent publications highlight methodologies for dual protein labeling, deciphering ubiquitin code, and enhancing cycloaddition reactivity. Current projects include exploring cyclopropene-fused dibenzocyclooctynes for improved labeling and investigating methylated lysine as a conformational regulator in Hsp90. Funding sources include the ERC (Ubl-tool), DFG (SFB1035, SPP1926), and ETH Zurich. She contributes to education through courses like Genetic Code Expansion for Studying Posttranslational Modifications and Chemical Biology and Synthetic Biochemistry . Collaborative efforts span structural biology, microbiology, and synthetic biochemistry, with applications in ubiquitin research and cellular imaging.
Dr. Hillel Adesnik is a Professor in the Department of Neuroscience at the University of California, Berkeley, and a leading researcher in the neural basis of sensory perception. His lab focuses on cortical microcircuits, optogenetics, and neural coding, with emphasis on visual processing and memory formation. Key Research Areas: Cortical Microcircuits Optogenetic Tools Gamma Band Rhythms Neural Coding Mechanisms Dr. Adesnik has pioneered high-speed optical methods like 3D-MAP and 3D-SHOT to manipulate neural activity. His work spans cortical dynamics, synaptic plasticity, and cortical layer interactions, with applications in understanding learning algorithms and sensory inference. Selected Trends from Publications: Recent preprints and papers highlight advancements in cortical VIP neuron function, channelrhodopsin structures, and inter-areal computations. His team utilizes two-photon holography, cryo-EM, and computational modeling to decode perception-related neural codes. Scientific Awards: NIH Director's New Innovator Award (2013) Dr. Adesnik's lab collaborates with institutions like NIH and develops tools for awake animal studies. Funding includes grants from the Beckman Young Investigator Program and NIH.
Hector Aguilar-Carreno is a Professor of Virology in the Department of Microbiology and Immunology at Cornell University's College of Veterinary Medicine, where he also serves as Associate Vice Provost in the Office of the Vice President for Research and Innovation. His research focuses on high-mortality paramyxoviruses including Nipah virus (NiV) and Hendra virus (HeV), as well as coronaviruses and other enveloped viruses. Dr. Aguilar-Carreno received his BS in Biochemical Engineering from Instituto Tecnologico de Tepic, Mexico, followed by an MS in Biology from California State University, Los Angeles, and a PhD in Biochemistry and Molecular Biology from the University of Southern California. He completed postdoctoral training in Virology at UCLA under Dr. Benhur Lee before becoming an Assistant Professor at Washington State University's Paul G. Allen School for Global Animal Health. His research spans four main areas: (1) Viral entry mechanisms, where his lab has identified novel domains in viral glycoproteins important for membrane fusion; (2) Viral egress, using multi-omics approaches to study viral assembly and budding; (3) Vaccine development using viral-like particles to generate neutralizing antibodies; and (4) Antiviral discovery targeting enveloped viruses. His lab employs innovative techniques including Flow Virometry and Raman Spectroscopy to study viral entry processes. Analysis of his recent publications reveals a strong focus on paramyxoviruses (particularly Nipah and Hendra viruses), coronavirus research, and the development of broad-spectrum antivirals. His work spans fundamental virology to translational applications, with numerous publications in high-impact journals including Nature, Science, and Cell Reports. President Elect of the American Society of Virology Chair of the American Society of Virology Diversity, Equity, and Inclusion committee Chair of the Cornell CVM Diversity Committee Director of the Cornell Program for Achieving Career Excellence Chair of 16 PhD student thesis committees Dr. Aguilar-Carreno has served on numerous scientific committees including the American Society for Virology Education Committee, the American Society of Microbiology Committee for Minority Education, and as a Standing Member of the VIR-A NIH study section. His leadership extends to chairing the Cornell CVM Diversity Committee and serving on the Cornell presidential postdoctoral fellowship committee, demonstrating significant commitment to diversity and mentorship in science.
