جست‌وجوی استاد و پژوهشگر

Jill Bargonettiمشاهده پروفایل

استاد

• Cancer Biology
• Breast Cancer Research
• Molecular Biology
• +۵ مورد دیگر

Jill Bargonetti is a Professor of Biological Sciences at Hunter College, City University of New York, where she holds the Hesselbach Professorship. She serves as Professor and past chair of the Molecular, Cellular, and Developmental Biology subprogram of the Ph.D. Program in Biology at The CUNY Graduate Center, and directs the NSF-funded NYRaMP.org post-baccalaureate program. Since 1994, she has led the Bargonetti Lab at Hunter College, conducting groundbreaking research in cancer biology. Dr. Bargonetti earned her B.A. at SUNY College at Purchase, followed by M.S. and Ph.D. degrees from New York University. She completed postdoctoral work at Columbia University (1990-1994). Her research focuses on signal transduction pathways converging on the tumor suppressor p53, particularly studying mutant p53 (mtp53), MDM2, and MDMX molecular pathways in breast cancer. She investigates p53-independent cell death pathways using human cancer cell line models, xenograft models, and C. elegans nematode models. Her innovative work includes developing the 'Choreographing Genomics' course that teaches genome information flow through post-modern dance movement and choreography, reflecting her background as a professional dancer. Her recent publications reveal strong trends in targeting mutant p53 pathways, particularly the mtp53-PARP-MCM axis, and exploring MDM2/MDMX roles in breast cancer metastasis. Her research spans molecular mechanisms of cancer, DNA repair pathways, and developing novel therapeutic approaches for treatment-resistant cancers, with significant emphasis on triple-negative breast cancer. Presidential Early Career Award for Scientists and Engineers (from President Bill Clinton) New York City Mayor's Award for Excellence in Science and Technology New York Voice Award Kathy Keeton Mountain Top Award from the NAACP Outstanding Woman Scientist Award from Association for Women in Science NYU and SUNY Purchase Outstanding Alumnae Achievement Awards Bronx High School of Science Hall of Fame Profiled by Working Mother as a 'Stellar Mom' Dr. Bargonetti has secured substantial research funding from the National Institutes of Health, National Science Foundation, Breast Cancer Research Foundation, METAvivor, American Cancer Society, and Department of Defense. She previously served on the NIH Tumor Cell Biology study section grant review panel (2012-2018). Her laboratory actively mentors undergraduate students through the Introduction to Experimental Biology course, with research opportunities in cancer biology and C. elegans genetics. The Bargonetti Lab continues to investigate mutant p53 pathways and develop novel approaches to target treatment-resistant breast cancer subtypes.

• Lipid systems
• Surface chemistry
• Lipid membranes
• +۶ مورد دیگر

Victor Agmo Hernandez is a Senior Lecturer and Associate Professor at Uppsala University's Department of Medicinal Chemistry, specializing in Analytical Pharmaceutical Chemistry and Pharmaceutical Physical Chemistry. His research focuses on lipid membrane systems and their applications in drug delivery and biosensing. Dr. Agmo Hernandez obtained his B.Sc. in Chemical Sciences from the Monterrey Institute of Technology in Mexico in 2002, followed by a Ph.D. in Analytical Chemistry from the University of Greifswald, Germany in 2008. After completing a postdoc at Uppsala University starting in 2008, he became a researcher at the Department of Chemistry-BMC in 2013 and was appointed Associate Professor (Docent) in 2014. His primary research interests include: Self-associated lipid systems and surface chemistry Properties of lipid membranes and their interactions with solutes Electrochemical and nanogravimetric (QCM-D) methods for studying lipid modified substrates Interactions of lipid membranes with peptides, proteins, and inorganic materials Development of lipodisks and other lipid-based drug delivery systems Analysis of his recent publications reveals a consistent focus on lipid membrane structure, stability, and interactions. His work spans fundamental biophysical studies of membrane properties to applied research in drug delivery systems, particularly using lipodisks for therapeutic applications. A notable trend is his expertise in using specialized measurement techniques like QCM-D, neutron reflectometry, and electrochemical methods to study membrane phenomena with high precision. Dr. Agmo Hernandez has received recognition for his work, with publications referenced in patents and cited by numerous researchers on platforms like Mendeley. His research group appears to focus on advancing our understanding of lipid membrane behavior while developing practical applications in drug delivery, particularly for cancer therapies and targeted treatments. Recent work shows continued innovation in optimizing lipodisk properties for specific therapeutic applications.

Joseph A. Murrayمشاهده پروفایل

استاد

• Celiac Disease
• Gluten Sensitivity
• Gastroenterology
• +۷ مورد دیگر

Joseph A. Murray is a Professor of Medicine at Mayo Clinic in Rochester, Minnesota, where he serves as a Consultant in the Division of Gastroenterology and Hepatology, Department of Internal Medicine, and holds a joint appointment in the Department of Immunology. He is affiliated with key research centers including the Robert and Arlene Kogod Center on Aging, the Immunology Research Center, and the Center for Cell Signaling in Gastroenterology (C-SiG). Education: MD, National University of Ireland, Galway Fellow, Gastroenterology-Hepatology, University of Iowa Hospitals and Clinics Tutor/Registrar, Medicine and GI, St. Laurences and Beaumont Hospitals, Dublin Senior House Officer, Internal Medicine, University of Dublin, Trinity College DCH, Child Health, National University of Ireland, University College of Dublin Internship in Medicine and Surgery, Regional Hospital, Galway MB BCh/BAO, National University of Ireland, Galway Dr. Murray's research focuses on celiac disease, gluten sensitivity, mucosal immunology, and autoimmune gastrointestinal disorders. His work integrates clinical investigation with molecular and immunological approaches, particularly in understanding the mechanisms of gluten-induced immune activation and developing novel diagnostic and therapeutic strategies. He has pioneered research on HLA mouse models of gluten sensitivity and clinical trials of enzyme-based therapies like latiglutenase. The trends in his recent publications reflect a strong emphasis on celiac disease pathogenesis, biomarker discovery, and therapeutic interventions. His studies explore T-cell activation, mucosal healing, biopsy quantification, and cross-disease autoimmunity, often involving multidisciplinary collaboration and translational applications. Scientific Awards: Dr. Murray has been principal or co-principal investigator on multiple NIH-funded grants, including projects from NIDDK, NIAID, and NCCIH, supporting research on tissue destruction and healing in celiac disease, clinical trials of latiglutenase, and the development of animal models for gluten sensitivity. While no formal students are listed, his leadership in large collaborative projects suggests mentorship of junior researchers and fellows. He is actively involved in the Clinical Immunology and Immunotherapeutics Program and has contributed to advancing the scientific understanding of celiac disease through sustained, high-impact research. Labs and Research Teams: Center for Cell Signaling in Gastroenterology (C-SiG) Clinical Immunology and Immunotherapeutics Program Collaborative research network involving Mayo Clinic, University of Chicago, Stanford, and University of Southern Denmark

• Leukemia
• Biostatistics
• Computational Biology
• +۶ مورد دیگر

Tim Triche, Jr., Ph.D., is an Associate Professor at the Van Andel Institute in the Department of Epigenetics . He earned his A.B. in chemistry from Cornell University , followed by an M.S. in biostatistics and a Ph.D. in statistical genetics from the University of Southern California . Before joining Van Andel in 2017, he was a postdoctoral fellow at USC's Norris Comprehensive Cancer Center focusing on cellular senescence in blood disorders. As a key member of The Cancer Genome Atlas Research Network since 2011 with over a dozen high-impact publications in Nature , Cell , and NEJM , Dr. Triche specializes in epigenetics , biostatistics , and computational biology . His lab develops innovative approaches for pediatric AML research, integrating next-generation sequencing with clinical trial design to improve patient outcomes. His work emphasizes statistical learning for patient stratification, molecular profiling of hematological cancers, and interpretable machine learning in biomedical contexts. He leads the Bioinformatics and Biostatistics Core as faculty advisor and maintains active collaborations across institutions. 2025 Nature Cancer study on developmental heterogeneity in cancer susceptibility 2024 NAR methods paper on BISCUIT multi-omics tools 2023 PLOS One validation of MAX regulation in pituitary adenomas 2022 Nature Metabolism obesity subtyping analysis Scientific contributions include: Chan Zuckerberg Initiative grant (2022) for biomedical computing NCI SPORE grant (2021) as co-recipient Key role in Pediatric AML molecular mapping (2017)

• Molecular Ecology
• Amphibian Conservation
• Phylogeography
• +۵ مورد دیگر

Dr. Inga Zeisset is a Senior Lecturer in the School of Applied Sciences at the University of Brighton, where she is part of the Ecology, Conservation and Society Research Excellence Group. Her work bridges molecular ecology with practical conservation applications, focusing particularly on amphibian species in Europe. Zeisset earned her BSc (Hons) in Ecology and Conservation with First Class honors from the University of Sussex (1994-1997), followed by a PhD in Molecular Ecology of North European Water Frogs from the same institution (1997-2001). Her doctoral research laid the foundation for her ongoing work in amphibian phylogeography and conservation genetics. Her research interests center on molecular ecology approaches to conservation challenges, with particular expertise in phylogeography, invasive species dynamics, the relationship between genetic diversity and fitness, adaptive genetic variation, and environmental DNA applications. Zeisset has developed specialized knowledge in amphibian conservation, particularly regarding pool frogs (Pelophylax lessonae) and their reintroduction to the UK. Her work frequently employs molecular methods including microsatellite analysis and MHC (Major Histocompatibility Complex) studies to address conservation questions. Analysis of her publication record shows a consistent research trajectory focused on amphibian conservation genetics, with recent work emphasizing practical conservation applications like species reintroduction monitoring and environmental DNA techniques. Her publications span molecular methodology development, phylogeographic studies, and applied conservation research, demonstrating how fundamental genetic research can inform conservation practice. The work shows increasing emphasis on practical conservation applications in recent years. Zeisset led the significant research project "Reintroduction of northern clade pool frogs (Pelophylax lessonae) to the UK" from 2014-2018, which represents a major contribution to amphibian conservation practice in Britain. Her supervisory interests include molecular ecology, amphibian ecology and conservation, phylogeography, species distribution, invasive species, and eDNA applications, indicating her commitment to training the next generation of conservation scientists. Her teaching philosophy emphasizes student-centered approaches, inquiry-based and cooperative learning. She incorporates practical sessions and group work into her lectures, providing guided reading and online resources to support deeper student engagement with course material outside the classroom.

Irene Athanassakisمشاهده پروفایل

استاد

• Immunology
• Molecular Biology
• Cell Biology
• +۳ مورد دیگر

Professor Irene Athanassakis is a faculty member at the Biology Department of the University of Crete. She holds a PhD in Biochemistry, Molecular Biology, Cellular and Developmental Biology from the University of Alberta (1988). Her research focuses on immunology, reproductive biology, and cancer diagnosis, with particular emphasis on MHC molecule regulation, T cell activation, and nonlinear optical imaging techniques. She leads a laboratory in the Biology building (Office: Γ 125, Lab: Ε 130) and has contributed extensively to understanding immune tolerance mechanisms and developing implantable vaccine technologies. Key research areas include soluble MHC antigens' role in immune modulation, diagnostic applications of third/harmonic generation microscopy for cancer grading, and the interplay between L-carnitine and endometriosis. Her work bridges molecular immunology with biomedical engineering, addressing clinical challenges in autoimmune diseases and cancer. Recent research trends highlight her contributions to SARS-CoV-2 immunogenicity studies, implantable vaccine design using laser-structured scaffolds, and machine learning-based analysis of biological samples. These studies underscore her interdisciplinary approach to solving complex biomedical problems. No scientific awards are explicitly listed in the provided materials. She advises no listed PhD/Master’s students but collaborates widely across disciplines. Her lab's activities include developing novel diagnostic tools and immunotherapeutic strategies, reflecting her commitment to translational research.

• Immunobiology of Herpesviruses
• Virology
• Infection and Immunity
• +۴ مورد دیگر

Professor Allison Abendroth is a faculty member at the University of Sydney, affiliated with the Central Clinical School and the Department of Infectious Diseases and Immunology. She holds the academic rank of Professor and leads the VZV Research Laboratory, the only lab in Australia dedicated to studying Varicella-Zoster Virus (VZV) immunobiology and pathogenesis. Her research focuses on herpesvirus immune evasion mechanisms, particularly VZV and cytomegalovirus (CMV), with a focus on antigen presentation, neuronal infection, and host-pathogen interactions. Abendroth completed her B.Sc (Hons) and PhD at the University of Adelaide/IMVS as a Dawes Scholar, followed by postdoctoral work at Stanford University under Prof. Ann Arvin. She has held roles as Sesqui Lecturer in Immunology and Honours Coordinator, while teaching senior immunology courses. Her work spans viral modulation of MHC molecules, cytokine regulation, and immune cell dysfunction. Key research interests include VZV’s impact on MR1 antigen presentation, MAIT cell suppression, and mechanisms of herpesvirus-induced apoptosis inhibition. She has contributed to studies on CMV latency in stem cell transplant recipients and the role of cytokines in viral reactivation. Her team uses models of neuronal infection and human ganglia studies to understand VZV neuropathogenesis. Abendroth has secured grants from NHMRC and other bodies for projects on viral immune evasion, latency, and host responses. The VZV Research Lab develops models for studying herpesvirus infection in neurons and immune cells, aiming to identify therapeutic targets for VZV-related diseases like herpes zoster and post-herpetic neuralgia.

• Cell Biology
• Immunology
• Molecular Biology
• +۳ مورد دیگر

Willem Stoorvogel is a Professor in the Department of Biomolecular Health Sciences at the Faculty of Veterinary Medicine, University of Utrecht. His research focuses on molecular mechanisms regulating endosome dynamics, antigen presentation via MHC class II molecules, and the immunological role of exosomes. He also investigates prostasomes in prostate biology. Department: Biomolecular Health Sciences School: Faculty of Veterinary Medicine University: University of Utrecht Research interests include: Endosome dynamics and sorting of medically relevant cargo molecules MHC class II processing and antigen presentation in immune responses Exosome biogenesis and immunological functions in antigen-presenting cells Prostasomes derived from prostate epithelial cells in semen Ubiquitination and intracellular transport mechanisms

Chelisa Cardinezمشاهده پروفایل

پژوهشگر ارشد

• Immunology
• Cancer Immunology
• Genomics
• +۴ مورد دیگر

Dr Chelisa Cardinez is a Postdoctoral Fellow at the Division of Genome Sciences and Cancer within the John Curtin School of Medical Research at ANU. Her research focuses on immunology, cancer immunology, and genetic disorders, with emphasis on mechanisms underlying immunodeficiencies and T-cell biology. She holds a BMedSci (Honours) degree and is registered to supervise research students. Her work combines molecular genetics (CRISPR/Cas9) and immunological approaches to study human immune deficiencies. Key projects include investigating gain-of-function mutations in IKBKB causing combined immunodeficiency and exploring CTLA4's role in T-cell cytotoxicity regulation. She collaborates with the Burr Group in cancer immunology and epigenetics. Current research highlights include a Tour De Cure-funded project (2023-2024) investigating MHC class II expression modulation to enhance anti-tumour immunity in melanoma. Her contributions bridge basic immunology research with translational applications in cancer therapy and genetic disease modeling.

• Glaucoma
• Open Angle Glaucoma
• Cataract Surgery
• +۵ مورد دیگر

Priv.-Doz. Dr. Andrea Zurl is a Research Associate at the University of Salzburg's Department of Ophthalmology, specializing in Experimental Ophthalmology and Glaucoma Research. With 86 peer-reviewed publications and 9 funded projects, her work focuses on retinal immunology, vascular degeneration, and pericyte biology. Glaucoma pathophysiology Retinal vascular remodeling Leukotriene receptor mechanisms Corneal regeneration techniques Alzheimer's disease ocular manifestations Recent articles demonstrate expertise in neuroimmune interactions (2025), gut-brain axis modulation (2025), and advanced imaging of optic nerve repair (2023). Current projects investigate pericyte-targeted therapies for neuroregeneration and diabetic retinal degeneration timelines.

Hidde Ploeghمشاهده پروفایل

استاد

• Immunology
• Biochemistry
• Antigen processing and presentation
• +۶ مورد دیگر

Hidde Ploegh is a Professor in the Department of Immunology at Harvard Medical School, where he leads a research laboratory at Boston Children's Hospital. His work bridges biochemistry and immunology, with a focus on understanding immune recognition mechanisms and pathogen evasion strategies. Harvard Medical School, Department of Immunology Boston Children's Hospital research lab Extensive research in molecular immunology and protein engineering Dr. Ploegh's research focuses on the biochemistry of immune recognition, particularly antigen processing and presentation through MHC molecules. His lab pioneered the use of 'sortagging' techniques and alpaca-derived nanobodies for both fundamental research and therapeutic applications. Current work emphasizes using nanobodies for non-invasive imaging of immune responses, particularly through positron emission tomography (PET), and developing novel approaches to modulate immune responses for cancer and autoimmune diseases. The Ploegh lab's publication record demonstrates consistent contributions to understanding immune recognition, with recent work highlighting applications of nanobody technology across immunology, cancer research, and protein engineering. Their research shows a clear trajectory from fundamental biochemical studies toward translational applications. Extensive work on nanobody technology and applications Innovative approaches to protein modification using enzymatic methods Development of imaging techniques for immune responses Applications in cancer immunotherapy and autoimmune disease Dr. Ploegh's laboratory has secured significant research funding to support their work on immune recognition mechanisms and nanobody applications. The lab actively trains graduate students and postdoctoral fellows, contributing to the next generation of immunologists and protein engineers. Recent collaborations demonstrate strong connections with clinical researchers working on cancer immunotherapy and autoimmune diseases. The Ploegh lab utilizes advanced techniques including sortase-mediated protein labeling, nanobody engineering, and mouse models of immune response. They maintain strong collaborations with chemistry and imaging specialists to advance their research goals, particularly in developing new approaches for visualizing and modulating immune responses.

Karen T. Hastingsمشاهده پروفایل

استاد

• Skin Cancer
• Immunology
• Dermatology
• +۶ مورد دیگر

Karen T. Hastings is a Professor and Inaugural Chair of the Department of Dermatology at the University of Arizona College of Medicine - Phoenix . Her research program focuses on antigen presentation , T cell responses , and neoantigen dynamics in skin cancer (melanoma and cutaneous squamous cell carcinoma). She leads a multidisciplinary team combining immunological , bioinformatic , and molecular biological approaches. Education: MD, PhD (Immunology) - Harvard University (2000) Residency - Yale New Haven Hospital (Dermatology, 2004) Postdoctoral Fellowship - Yale University (Immunobiology, 2006) Research Interests encompass skin cancer immunobiology , antigen processing , immune checkpoint regulation , and bioinformatics modeling of neoantigen landscapes. Her lab has defined GILT as a critical enzyme in MHC class II antigen presentation and investigates its role in tumor-immune interactions using: Genetically engineered mouse models Human tumor specimen analysis Transcriptomic profiling Multi-omics integration Immune cell deconvolution Her scientific contributions include: Elucidating GILT's role in central T cell tolerance Developing neoantigen prediction frameworks Characterizing immune infiltration patterns in viral-mediated HCC Identifying sex-based molecular differences in HCC Trainees under her mentorship have received NIH F30 grants , Medical Student Awards , and travel awards to international conferences. The Hastings Lab collaborates with researchers at Arizona State University and participates in translational cancer research initiatives.

Karen Kiemnec-Tyburczyمشاهده پروفایل

دانشیار

• Evolutionary Biology
• Molecular Biology
• Zoology
• +۵ مورد دیگر

Karen Kiemnec-Tyburczy is an Associate Professor in the Department of Biological Sciences at California State Polytechnic University, Humboldt. With a PhD in Zoology from Oregon State University and postdoctoral experience at Cornell University, her research focuses on the evolution of natural vertebrate populations, particularly amphibians, integrating molecular biology, genetics, and behavior. BS & PhD: Oregon State University Postdoc: Cornell University Current role: Associate Professor (tenured since Fall 2025) Her research spans three major areas: Chemical communication in salamanders - Examining olfactory morphology and gene expression patterns across species with diverse life histories, funded by an NSF IOS grant Amphibian population genetics - Investigating evolutionary relationships in Rhyacotriton variegatus and Ascaphus truei through population genetics Pathogen detection in amphibians - Collaborative work with U.S. Bureau of Land Management and Save the Redwoods League on ranavirus and chytrid fungus surveillance Recent publications highlight her work in immunogenetics (MHC gene evolution), behavioral ecology (courtship dynamics), and conservation biology (pathogen impacts). She has received multiple grants including an NSF IOS grant and CSUBIOTECH travel grant for Oxford Nanopore Technologies training. NSF IOS grant: 'Smelling in water and air: Evolution of olfaction in plethodontid salamanders' CSUBIOTECH travel grant Ferguson grant for undergraduate research support Karen co-advises graduate students including Emily Gremling, Giusy Lanzilli, and Marilyn Sandoval, whose theses explore olfactory system morphology and gene expression in plethodontid salamanders. Her lab maintains active collaborations with researchers like John Reiss and focuses on integrating biotechnology into STEM education through courses like 'Becoming a STEM Scientist' (SCI 100).

Georg Dudaمشاهده پروفایل

استاد

• Protein Biochemistry
• RNA Biochemistry
• Antigen Presentation
• +۳ مورد دیگر

Georg Duda is a Coopted Professor affiliated with the Department of Biochemistry under the School of Chemistry and Biochemistry at Freie Universität Berlin. His research is associated with multiple groups, including the Freund Group and Knaus Group, focusing on protein-RNA interactions and membrane dynamics. Research Focus: Antigen presentation by MHC Class II proteins, RNA metabolism, and membrane trafficking mechanisms. Awards: Einstein Visiting Fellow by the Einstein Foundation Berlin. Recent Work: Investigated SARS-CoV-2 Nucleocapsid protein interactions with human NMD factors, revealing molecular pathways in viral pathogenesis.

Gerhard Eckerمشاهده پروفایل

استاد

• Pharmacoinformatics
• Drug Design
• Transmembrane Transport Proteins
• +۴ مورد دیگر

Gerhard Ecker is a Professor of Pharmacoinformatics and Head of the Pharmacoinformatics Research Group at the Division of Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna. He serves as Director of Corporate Program and has held significant leadership roles including Dean of the Faculty of Life Sciences (2018-2022) and Vice-Dean (2014-2018). His educational background includes Pharmacy studies at the University of Vienna (1981-1986), Ph.D. in Medicinal Chemistry (1986-1991), a post-doctoral stay at the Research Center in Borstel, Germany (1995), and Habilitation for Pharmaceutical Chemistry at the University of Vienna (1998). He was appointed as full professor for Pharmacoinformatics at the University of Vienna in October 2009. Professor Ecker's research focuses on computational drug design with special emphasis on drug-transporter interactions and in silico safety assessment. His work spans ligand- and structure-based drug design , particularly focused on transmembrane transport proteins , prediction of on- and off-kinetics , and semantic data integration . His group employs advanced computational techniques including machine learning, neural networks, protein homology modeling, and molecular dynamics simulations to address challenges in pharmacology and toxicology. An analysis of his recent publications reveals a strong focus on solute carrier (SLC) transporters, with numerous studies on SLC6 family members and their role in disease. His work increasingly integrates machine learning approaches with structural biology to predict mutation pathogenicity, transporter inhibition, and drug safety profiles. The research demonstrates a clear trajectory toward more sophisticated computational models that combine chemical and biological fingerprints for improved prediction accuracy. Fellow of the Royal Society of Chemistry (2013) Professor Ecker has coordinated or participated in numerous significant research projects including the Open PHACTS project (semantic integration of public databases), and serves as Speaker of the FWF doctoral programme "Molecular Drug Targets." He has been involved in multiple EU-funded initiatives such as eTOX, K4DD, eTRANSAFE, TransQST, ReSOLUTE, and Risk-Hunt3r, as well as FWF projects like InSilify DrugTox and Vienna Business Agency's AI4HEALTH. He leads the Pharmacoinformatics Research Group at the University of Vienna, which focuses on developing computational methods for drug design and safety assessment. The group is actively involved in several major collaborative projects including RISK-HUNT3R (focusing on chemical risk assessment) and ReSOLUTE (research on solute carriers for drug discovery). Their work bridges computational approaches with experimental validation to address key challenges in pharmaceutical sciences.