جست‌وجوی استاد و پژوهشگر

Daiwei Zhangمشاهده پروفایل

استادیار

• Artificial Intelligence
• Machine Learning
• Spatial Omics
• +۳ مورد دیگر

Daiwei (David) Zhang, PhD, is an Assistant Professor (tenure-track) in the Department of Biostatistics at the University of North Carolina at Chapel Hill School of Medicine, with a joint appointment in the Department of Genetics. His research focuses on developing AI frameworks for analyzing high-dimensional biomedical data, particularly in spatial omics, computational pathology, and medical imaging. Education: MS (Biostatistics) and PhD (Biostatistics and Scientific Computing) from the University of Michigan. Postdoctoral Training: University of Pennsylvania. Research interests include applying machine learning to address biomedical challenges such as tumor heterogeneity, immune interactions, and tissue architecture. His work spans computational methods for spatial transcriptomics, proteomics, and histology integration. Recent publications emphasize spatial multi-omics analysis of cancer ecosystems, tertiary lymphoid structures, and metabolic coordination. These studies leverage advanced machine learning algorithms and interdisciplinary approaches to advance precision medicine. No scientific awards are explicitly mentioned, but his work reflects significant contributions to biomedical AI research. Grants and advising details are not provided in the text.

Aaron Loganمشاهده پروفایل

دانشیار بالینی

• Hematology
• Oncology
• Immunology
• +۳ مورد دیگر

Dr. Aaron Logan is a Clinical Associate Professor of Medicine at the University of California, San Francisco (UCSF). He specializes in the clinical management of acute leukemias, myelodysplastic syndromes, aplastic anemia, and hemophagocytic lymphohistiocytosis. Additionally, he directs a research laboratory focused on immune repertoire profiling following hematopoietic cell transplantation. MD and PhD in Molecular Microbiology and Immunology from Keck School of Medicine (2006) MPhil in History of Medicine from University of Cambridge (2005) Internal Medicine Residency and Hematology Fellowship at Stanford University Dr. Logan's research explores clonotypic diversity in B and T lymphocyte repertoires, utilizing techniques like TREC/KREC quantification, high-throughput sequencing, and mixed lymphocyte reactions. His work has significant applications in tracking immune responses post-transplantation and quantifying measurable residual disease in lymphoid cancers. Notable scientific contributions include advancements in CAR T-cell therapy and immune profiling for blood malignancies. His publications cover topics in B-cell ALL , AML , and measurable residual disease monitoring. 2020 - UCSF Hematology-Oncology Fellowship Teaching Award 2011 - ASH Abstract Award and Research Training Award 2003 - Keck School of Medicine Outstanding Teaching Award As director of the UCSF Hematologic Malignancies Tissue Bank, Dr. Logan provides deidentified patient samples to support collaborative research on blood cancers and post-transplantation immune dynamics.

Omer Bayraktarمشاهده پروفایل

پژوهشگر

• Neural Diversity
• Spatial Transcriptomics
• Glia Biology
• +۳ مورد دیگر

Omer Bayraktar is a Group Leader at the Wellcome Sanger Institute , leading research in the Cellular Genomics Programme. His work focuses on decoding human brain cellular diversity using spatial transcriptomics , imaging , and functional screening to study neural complexity in health and disease. Bayraktar's educational background includes a PhD from HHMI under Chris Doe, investigating neural diversity development in Drosophila , followed by postdoctoral work at University of California, San Francisco and University of Cambridge as a Life Sciences Research Foundation Fellow. He developed a spatial transcriptomic pipeline during his postdoc to analyze astrocyte heterogeneity in the cerebral cortex. His research explores neural cell type mapping , glial-neuronal interactions , and cellular pathways in neurodevelopmental disorders . Recent publications emphasize 3D tissue mapping , multi-omic integration , and computational tools like Cell2fate and WebAtlas. His work bridges neurogenetics and computational biology to advance understanding of human tissue ecosystems. Bayraktar's lab collaborates with the Human Cell Atlas initiative and develops technologies such as automated histology pipelines and highly-multiplexed smFISH for molecular cell typing. His team also investigates glia-based therapies and astrocyte functional heterogeneity in neurodevelopmental contexts. Key scientific contributions include: Discovering astrocyte layer patterns independent of neuronal laminae Developing cell2location for spatial cell mapping Characterizing Drosophila neural stem cell models with human relevance Notable awards include the Life Sciences Research Foundation Fellowship during his postdoctoral training. His current group includes a PhD student , Senior Data Scientists , and Bioinformaticians .

Kenneth Hoehnمشاهده پروفایل

استادیار

• Computational Immunology
• Evolutionary Biology
• B Cell Biology
• +۵ مورد دیگر

Kenneth Hoehn is an Assistant Professor in the Department of Biomedical Data Science at the Geisel School of Medicine, Dartmouth College. As a computational immunologist with expertise in evolutionary biology, he develops computational evolutionary approaches to trace cellular lineages, particularly B cells, in contexts such as infection, vaccination, cancer, and autoimmune diseases. His research focuses on understanding adaptive immunity in conditions like COVID-19 Food allergies Myasthenia gravis through collaborations with experimental teams. Key projects include: Phylogenetic modeling of B cell responses Evolutionary signatures in immune repertoires Tracking B cell dissemination in autoimmune diseases Epigenetic regulation of memory B cells Recent publications highlight trends in single-cell immunology , phylogenetic inference , and computational tools for analyzing B cell dynamics. His lab at Dartmouth integrates evolutionary genetics with high-resolution immune profiling.

Pierette Appasamyمشاهده پروفایل

مدرس

• Development and evolution of the immune system
• Skin and mucosal immune responses
• Gamma delta T cell biology
• +۷ مورد دیگر

Pierette Appasamy is a Lecturer in the Department of Biology at Chatham University’s College of Arts & Sciences. With a Ph.D. in Anatomy & Developmental Biology from Thomas Jefferson University, she has over three decades of experience in immunology research and education. Her career spans roles at the University of Pittsburgh School of Medicine, NIH-funded research, and current work at Chatham since 2007. B.S., Biology, cum laude, Xavier University (1982) Ph.D., Anatomy & Developmental Biology, Thomas Jefferson University (1988) Post-Doctoral Fellowship, Immunology, University of Pennsylvania (1987-1990) Her research focuses on the evolution and development of gamma delta T cells , IL-7 signaling pathways in amphibians, and psychosocial-immune interactions in college students . She employs Xenopus frogs as a model organism to study non-conventional lymphocyte biology and wound healing immunology. Recent publications highlight her work on cytokine evolution and stress-immune-microbiome dynamics , with collaborations at the University of Pittsburgh’s Center for Medicine and the Microbiome. Her pedagogical innovations include role-playing and analogies to enhance immunology education. NIH R29 Grant (Principal Investigator) NIH R01 Grant (Co-Investigator) MacArthur Foundation Grant (Yale Subcontract) American Cancer Society Grant Chatham University Technology Fellowship Award American Association of Immunologists Travel Grant She mentors students in laboratory research and serves as Chatham’s Pre-Med Advisor. Her lab combines molecular techniques, tadpole thymus microsurgery, and behavioral studies to explore immunological questions with clinical relevance.

Christina Leslieمشاهده پروفایل

استاد پژوهشی

• Computational Biology
• Systems Biology
• Machine Learning
• +۷ مورد دیگر

Dr. Christina Leslie is a Research Professor and Member of the Computational & Systems Biology Program at Memorial Sloan Kettering Cancer Center (MSK). She leads an active research laboratory focused on developing computational approaches to understand complex biological systems. Dr. Leslie earned her PhD from the University of California, Berkeley and has established herself as a leading computational biologist in cancer research and immunology. Computational & Systems Biology Program, Memorial Sloan Kettering Cancer Center Gerstner Sloan Kettering Graduate School of Biomedical Sciences Dr. Leslie's research focuses on developing novel computational methods to study cellular biological systems from a global and data-driven perspective. Her lab exploits diverse high-throughput functional and genomic data to understand molecular networks underlying fundamental cellular processes, including transcription regulation, pre-mRNA processing, signaling, and post-transcriptional gene silencing. Her algorithmic methods draw heavily on machine learning to build accurate predictive models from noisy and high-dimensional biological data. Key areas of interest include modeling cell-type specific transcriptional programs and dissecting co- and post-transcriptional regulation, particularly microRNA-mediated gene regulation. Analysis of Dr. Leslie's publication record over the last five years reveals a strong focus on computational approaches to cancer genomics, immunology, and epigenetics. Her work bridges multiple disciplines, with a particular emphasis on developing machine learning methods to interpret complex biological data. The publications demonstrate increasing sophistication in integrating multiple data types (genomic, transcriptomic, epigenomic) to understand cancer biology and immune responses. Recent work shows a growing emphasis on single-cell technologies and spatial analysis of tumor microenvironments. Introduction of string kernel methodology for SVM classification of biological sequences Development of algorithms for predictive modeling of gene regulation First systems-level analyses of competition between microRNAs and between target transcripts Dr. Leslie actively mentors numerous graduate students and research associates, with current lab members including Vianne Gao, Alireza Karbalaghareh, Erik Ladewig, and several others. Her lab has received significant research funding to support their work on computational approaches to cancer biology and immunology. The Leslie Lab maintains close collaborations with multiple experimental groups at MSK, facilitating the translation of computational insights into biological understanding. The Leslie Lab operates within the Computational & Systems Biology Program at MSK, with strong ties to both the research and clinical missions of the institution. The lab maintains state-of-the-art computational infrastructure for analyzing large-scale genomic and proteomic datasets and collaborates extensively with wet-lab researchers to validate computational predictions experimentally.

• Cancer Immunology
• Innate Lymphoid Cells
• Regulatory T Cells
• +۵ مورد دیگر

Dr. Tim Halim is a Sir Henry Dale Fellow and Junior Group Leader at the Cancer Research UK Cambridge Institute (CRUK Cambridge Institute), University of Cambridge. His primary research program focuses on pancreatic cancer, with thoracic cancer as a secondary research focus within the CRUK Cambridge Centre's structured research programs. Dr. Halim's research expertise lies at the intersection of cancer biology and immunology, with particular emphasis on innate lymphoid cells (especially ILC2) and regulatory T cells within the tumor microenvironment. His work investigates how these immune cell populations interact with cancer cells and influence tumor progression, metastasis, and response to therapy. His research has significant implications for developing novel immunotherapeutic approaches for pancreatic and thoracic cancers. His publication record demonstrates a consistent focus on the role of innate lymphoid cells in cancer, with recent work examining IL-33 and ILC2 in pancreatic cancer, cross-talk between ILC2 and regulatory T cells, and the influence of innate lymphoid cells on pancreatic stromal composition. His research employs advanced techniques including in vivo labeling, single-cell analysis, and fate-mapping approaches to understand immune cell behavior in cancer contexts. Dr. Halim has been awarded the prestigious Sir Henry Dale Fellowship, a joint fellowship from the Royal Society and Wellcome Trust that supports early-career researchers of outstanding promise working at the interface of basic and clinical science.

• Cancer Genomics
• Liquid Biopsies
• Machine Learning in Oncology
• +۷ مورد دیگر

Ash A. Alizadeh is the Moghadam Family Professor of Medicine, Oncology, and Hematology (by courtesy) at Stanford University, where he serves as leader of the Cancer Genomics Program at Stanford Cancer Institute. He holds multiple academic appointments including Professor in Medicine - Oncology, and membership in Bio-X, the Institute for Stem Cell Biology and Regenerative Medicine, and the Maternal & Child Health Research Institute (MCHRI). Dr. Alizadeh received his BS in Biochemistry from UCLA (1994), MD from Stanford Medical School, and PhD in Biophysics from Stanford. He completed additional training at the National Cancer Institute (NCI), the National Institutes of Health (NIH), and the Howard Hughes Medical Institute (HHMI). His primary research focuses on developing and applying genome technologies and computing (machine learning & data science) to problems in human disease, with special emphasis on cancer detection, classification, monitoring, and tumor immunology. His laboratory pioneers noninvasive cancer genomic techniques including CAPP-Seq, PhasED-Seq, and EPIC-Seq for "liquid biopsies" that analyze circulating nucleic acids for early cancer detection and monitoring therapeutic response. Using machine learning approaches, his group studies how cellular compositional variation impacts cancer behavior and therapeutic response, including anti-tumor immunity. His work spans molecular, cellular, organism and population levels of tumor behavior analysis. Dr. Alizadeh has received numerous prestigious awards including the Scholar Award from the American Society of Hematology (ASH), the Leukemia & Lymphoma Society (LLS), the V-Foundation, as well as awards from the American Red Cross, Damon Runyon Cancer Research Foundation, and Doris Duke Charitable Research Foundation. He is an elected member of the American Society for Clinical Investigation (ASCI) and serves on the Scientific Advisory Board of the Lymphoma Research Foundation (LRF). As an educator and mentor, Dr. Alizadeh advises numerous doctoral students, postdoctoral fellows, and medical scholars. He teaches in the Department of Medicine and Immunology and serves on various admissions panels at Stanford. His laboratory, the Alizadeh Lab, is a hub for interdisciplinary cancer genomics research that combines computational biology, molecular genetics, and clinical oncology to develop novel cancer diagnostics and therapeutics.

• Mucosal Immunology
• Intestinal Microbiota
• Host-Immune System Interaction
• +۳ مورد دیگر

Dame Fiona Powrie is a Professor of Musculoskeletal Sciences at the University of Oxford and Director of the Kennedy Institute of Rheumatology . She leads the Mucosal Immunology Research Group and serves as Director of the Oxford Centre for Microbiome Studies (OCMS) and Cluster Lead in the MRC National Mouse Genetics Network Microbiome Cluster . Roles: Director of Kennedy Institute, Professor, Research Group Leader Relevant Affiliations: Wellcome Trust Governor (2018–present), Deputy Chair (2022), Royal Society Fellow (2011) Research Interests : Fiona specializes in the interplay between the intestinal microbiota and the host immune system, focusing on how dysregulation leads to inflammatory bowel disease (IBD) . Her work has elucidated the role of regulatory T cells in maintaining gut homeostasis and identified the IL-23 pathway as critical in chronic intestinal inflammation. Current efforts aim to translate these findings into clinical therapies for IBD patients. Scientific Awards and Fellowships : Ita Askonas Award (European Federation of Immunological Societies) Louis-Jeantet Prize for Medicine (2012) Honorary Lifetime Membership (British Society of Immunology, 2021) Fellow of the Royal Society (2011), EMBO (2013), Academy of Medical Sciences (2014) International Fellow of the National Academy of Sciences (2020) Advising and Leadership : Fiona leads the Mucosal Immunology group at the Kennedy Institute, mentors researchers, and contributes to national and international scientific governance. She has been instrumental in advancing microbiome and immunology research through leadership roles at the Oxford Centre for Microbiome Studies and the MRC National Mouse Genetics Network . Labs and Teams : Fiona's research group at the Kennedy Institute of Rheumatology investigates mucosal immunity and microbiome interactions, combining experimental and clinical approaches to address inflammatory diseases.

• Mathematical Biology
• Cancer Evolution
• Computational Biology
• +۴ مورد دیگر

Dr. Calum Gabbutt is a Chapman-Schmidt AI in Science Postdoctoral Research Fellow at Imperial College London's Department of Mathematics (Faculty of Natural Sciences) and a Postdoctoral Training Fellow at the Institute of Cancer Research (ICR), London. He holds a PhD in Mathematical Biology from Queen Mary University of London (2017–2021) and an MPhys from the University of Oxford (2013–2017). His research focuses on mathematical and computational methods to understand clonal dynamics and cancer evolution, particularly leveraging genomic and lineage tracing data. He develops Bayesian inference models to analyze evolutionary processes in cancer, aiming to improve clinical outcomes through precision medicine. Key areas include genetic barcoding, methylation-based molecular clocks, and phylogenetic reconstruction of tumor evolution. Recent work spans large-scale genomic analyses of cancer evolution, computational tools like PISCA-box for somatic chromosomal alterations, and studies on phenotypic plasticity in metastasis and therapy resistance. His research integrates AI-driven approaches to decode cancer heterogeneity and temporal dynamics in human tissues. Collaborations span institutions like the ICR and Queen Mary University of London, emphasizing interdisciplinary methods at the intersection of mathematics, computational biology, and oncology.

Richard Gaultمشاهده پروفایل

مدرس

• Computer Vision
• Medical Image Analysis
• Artificial Intelligence
• +۳ مورد دیگر

Dr. Richard Gault is a Lecturer in the School of Electronics, Electrical Engineering and Computer Science at Queen's University Belfast. His research focuses on computer vision and deep learning applied to microscopy data, particularly in medicine, health, and life sciences. He leads a team developing novel methods for medical image analysis, including histopathology and digital pathology, with applications in cancer diagnosis and environmental science. He is actively involved in teaching, having received Excellence in Teaching awards from Queen's University Belfast in 2019 and 2022. His work bridges computational intelligence and healthcare, with notable contributions to AI-driven diagnostics, stain normalization in histopathology, and multimodal data fusion. Dr. Gault's research interests include ensemble learning, fuzzy systems, and generative models like diffusion networks. He supervises multiple PhD students and has mentored graduates now working in machine learning engineering and postdoctoral research. His team’s achievements include awards such as the 2023 Best Oral Presentation at the Pan Ireland Ophthalmology Day and a 2021 Best Paper Award from his school. Key contributions include the LymphoSight AI application for detecting lymphoid structures and HistoClean , open-source software for improving CNN development in histopathology. He has been recognized as a Senior Member of IEEE and a Fellow of the Higher Education Academy. His work is supported by grants such as the R5131ECI project on 3D quantifier approximation via 2D video analysis (2019–2025). He actively engages in academic activities, including conference organization and PhD external examinations across Europe.

Anne Berit C. Samuelsenمشاهده پروفایل

دانشیار

• Polysaccharide Chemistry
• Pharmacognosy
• Carbohydrate Polymers
• +۴ مورد دیگر

Anne Berit C. Samuelsen serves as Associate Professor at the Department of Pharmacy, University of Oslo, where she also holds the position of Head of Education. Her academic foundation includes a Cand.pharm. degree and Dr.scient. doctorate, establishing her expertise in pharmaceutical sciences. Her research centers on polysaccharides from natural sources—particularly higher plants, cereals, and fungi (Basidiomycota)—with specialized focus on β-glucans. Key interests include carbohydrate chemistry, pharmacognosy, and the development of biopolymer-based pharmaceutical applications. Her work bridges fundamental structural characterization with practical drug delivery solutions, notably through liposome coating technologies and immunomodulatory compound development. Recent publications reveal a strong trajectory in fungal polysaccharide research, particularly with Pleurotus eryngii and Albatrellus ovinus species. Her team employs advanced techniques like diffusion-ordered NMR spectroscopy to analyze polysaccharide structures while investigating biological activities related to immune receptor binding (Dectin-1, Toll-like receptors) and therapeutic applications. This work demonstrates consistent output in high-impact journals including Carbohydrate Polymers and ACS Applied Bio Materials . She actively contributes to academic instruction through courses such as FARM1150 (Pharmaceutically Oriented Biochemistry), FARM3100 (Pharmacognosy), and FARM5200 (Use of Biopolymers in Pharmaceuticals). Her leadership extends to the Bioactive Natural Substances and Health Effects (BioNatH) research group and the Glyconor Consortium, where she investigates natural product applications for health improvement.

• Cancer Immunology
• Immunotherapy
• Tumor Microenvironment
• +۳ مورد دیگر

Kelli Connolly is an Associate Research Scientist at the Yale School of Medicine, Yale University. Her research focuses on cancer immunology, with a particular emphasis on tumor immunity, T cell biology, and neoantigen-driven immune responses. She develops and utilizes mouse models to investigate mechanisms underlying anti-tumor immunity, including T cell exhaustion, tertiary lymphoid structures in cancer, and the role of stem-like T cells in sustaining immune responses. Her work bridges basic immunology and translational cancer research, aiming to improve immunotherapy strategies. Key Collaborations: Works closely with researchers like Nikhil Joshi, Gena Gora Foster, and Julie F. Cheung. Research Themes: Neoantigen expression, tumor-draining lymph node dynamics, and combination therapies targeting the immune microenvironment. Her studies highlight the importance of lineage fidelity in CD8 T cells and the role of transcription factors like KLF2 in suppressing exhaustion. She also explores how modulating chemokine axes (e.g., CCR2/CCR5) enhances radiotherapy efficacy. Connolly’s contributions span preclinical models for lung and pancreatic cancers, emphasizing the interplay between tumor biology and immunological mechanisms. Publications span journals like Science , Cell , and Nature Biotechnology , reflecting her impact in cancer immunology and translational research.

Rex Hungمشاهده پروفایل

دانشیار

• Bone and Soft Tissue Pathology
• Cardiovascular Pathology
• Pulmonary Pathology
• +۳ مورد دیگر

Rex Hung is an Associate Professor of Pathology at Harvard Medical School and serves as an Associate Pathologist at Massachusetts General Hospital . His academic career focuses on Bone and Soft Tissue Pathology , Cardiovascular Pathology , and Pulmonary Pathology , with significant contributions to cancer research.

• Gastrointestinal Pathology
• Inflammatory Bowel Disease
• Colorectal Carcinoma
• +۷ مورد دیگر

Lindsay Alpert is an Associate Professor in the Department of Pathology at the University of Chicago's Pritzker School of Medicine. As a surgical pathologist specializing in gastrointestinal pathology, Dr. Alpert provides expert diagnostic services for neoplastic and non-neoplastic diseases of the gastrointestinal tract, biliary tree, and pancreas. Dr. Alpert received her MD from Columbia University College of Physicians and Surgeons in 2012. She completed her residency in Anatomic Pathology and fellowship in Gastrointestinal and Hepatic Pathology at the University of Chicago, finishing her fellowship in 2016 and residency in 2017. Dr. Alpert's research focuses on gastrointestinal pathology with particular expertise in inflammatory bowel disease, colorectal carcinoma, and the gut microbiome. Her work examines dysplasia patterns in IBD patients, histologic features of enteropathies, and the impact of therapeutic interventions on gastrointestinal tissues. She has made significant contributions to understanding the histologic spectrum of various gastrointestinal conditions and their clinical implications, with numerous publications in high-impact journals like Modern Pathology and Gastroenterology. Analysis of Dr. Alpert's recent publications reveals a strong focus on gastrointestinal pathology, particularly inflammatory bowel disease and colorectal neoplasia. Her work spans diagnostic pathology, molecular characterization of gastrointestinal tumors, and the impact of therapeutic interventions. Many studies examine dysplasia patterns in IBD patients across different age groups and presentations, while others investigate rare gastrointestinal conditions and their histologic features. Her research often bridges basic science with clinical applications, examining how dietary and pharmacological factors influence gastrointestinal pathology. Dr. Alpert actively collaborates with numerous researchers and clinicians at the University of Chicago and beyond, contributing to multidisciplinary studies that bridge pathology with clinical gastroenterology and oncology. Her network includes prominent colleagues such as John Hart, Namrata Setia, and Shu-Yuan Xiao. Dr. Alpert maintains an active research laboratory focused on gastrointestinal pathology, where she mentors trainees and collaborates with colleagues on various research projects examining the histopathology of gastrointestinal diseases. Her team works closely with clinicians to translate pathological findings into improved diagnostic criteria and patient care, particularly for complex cases involving inflammatory bowel disease and gastrointestinal neoplasia.