جست‌وجوی استاد و پژوهشگر

Pierre-Marie Lledoمشاهده پروفایل

پژوهشگر

• Sensory systems
• Neuroplasticity
• Adult neurogenesis
• +۵ مورد دیگر

Pierre-Marie Lledo is a leading neuroscientist at the Pasteur Institute in Paris, France. He serves as Head of the Perception and Memory Laboratory , Director of the CNRS Unit Genes, Synapses and Cognition , and Director of the Teaching Graduate Program in Neuroscience . A dual citizen of France and international neuroscience collaboration through his CoNCEPT project with McMaster University, Lledo maintains affiliations with prestigious institutions including CNRS (since 2004) and Academia Europaea (since 2006). His research focuses on adult neurogenesis and olfactory system plasticity , exploring how sensory experiences shape lifelong brain wiring. This work bridges molecular and systems neuroscience, with implications for developmental disorders , learning mechanisms , and mood regulation . Notably, Lledo's team investigates the microbiota-gut-brain axis , neuroimmune interactions , and amygdala circuitry in affective disorders. Recent publications highlight his groundbreaking work on depression models and neurodegenerative mechanisms , particularly exploring venous lymphatic brain clearance and vagal pathways in sepsis-related brain dysfunction. His 2025 Neuron study on olfactory hedonic biases in depression models demonstrates his continued leadership in affective neuroscience. Scientific distinctions : CNRS Medal for best Junior Scientist (1995) Prime d'Excellence Scientifique (CNRS, 2011) NRJ Award (French Academy of Science, 2005) Educational contributions include: Coordinating the intensive Pasteur Course on Development and Plasticity of the Nervous System Organizing international symposia on neurogenesis and brain plasticity Mentoring 22 Ph.D. and Master's students since 1993

• Mammalian circadian oscillators
• Pancreatic islet cell clocks
• Chrono-immunometabolism
• +۷ مورد دیگر

Dr. Charna Dibner is an Associate Professor and Head of the Laboratory of Circadian Endocrinology at the Faculty of Medicine, University of Geneva . Her research bridges molecular circadian oscillators with metabolic diseases and cancer , utilizing genetic rodent models and human primary cell methodologies . Key collaborations span Departments of Surgery, Medicine, Oncology, and Pathology at Hôpitaux Universitaires de Genève (HUG). Education: PhD in Medical Sciences, Department of Biochemistry, Technion Israel Institute of Technology (2003) MSc in Pharmacology, Technion Israel Institute of Technology BSc in Biology, cum laude, Technion Israel Institute of Technology Research Focus: The Dibner lab investigates cell-specific circadian clocks in pancreatic α- and β-cells, their role in islet function and regeneration , and clock dis-regulation in diabetes and cancer. Her team pioneers real-time bioluminescence recording and chrono-immunometabolism approaches in human tissues. Publications Trends: Recent works emphasize circadian lipid metabolism , chronotherapeutics , and clock-immune interactions in cancer immunotherapy. Collaborative studies map diurnal lipid oscillations and clock-driven purine synthesis . Scientific Recognition: Roche Research Foundation Postdoctoral Fellowship (2003) & Award (2004) Takeda Foundation Award (2011) Leenaards Prize (2019) ISREC Tandem Grant (2023) Funding: Continuously supported by Swiss National Science Foundation , European Foundation for the Study of Diabetes , Swiss Cancer League , and private foundations since 2009. Laboratory: Part of the Faculty Diabetes Center and Translational Chronobiology and Chronomedicine group, developing chrono-based clinical applications and personalized time-dependent treatments .

Anthony Rosenzweigمشاهده پروفایل

استاد

• Cardiovascular Research
• Heart Failure
• Exercise Physiology
• +۵ مورد دیگر

Dr. Anthony Rosenzweig, Professor of Internal Medicine - Cardiology at the University of Michigan Medical School, is a leading figure in cardiovascular research with a focus on heart failure, exercise physiology, and molecular cardiology. He previously held the Paul Dudley White Professorship of Medicine at Harvard Medical School (2015-2022) and served as Chief of Cardiology and Director of Cardiovascular Research at Massachusetts General Hospital. Harvard College (Biochemistry & Molecular Biology) Harvard Medical School (MD) Massachusetts General Hospital (Residency & Fellowship) University of Pennsylvania (Predoctoral Fellowship) Harvard Medical School (Postdoctoral Training) His research spans multiple groundbreaking areas including: Exercise-induced cardiac lymphatic remodeling for aging heart inflammation miRNA-based therapies for chemotherapy-induced cardiotoxicity Traditional Chinese Medicine applications in heart failure treatment (QLQX clinical trials) Stem cell-derived cardiomyocyte purification techniques Neural pathways linking stress to cardiovascular benefits Placental senescence mechanisms in peripartum cardiomyopathy Scientific contributions include leadership in the QUEST trial showing Qiliqiangxin's efficacy for HFrEF and pioneering work on exercise-regulated noncoding RNAs reversing vascular aging. He currently directs the Stanley and Judith Frankel Institute for Heart and Brain Health at University of Michigan. Paul Dudley White Professor of Medicine (2015-2022) Inaugural Director, Frankel Institute for Heart and Brain Health Leadership roles at MGH, Beth Israel Deaconess, and Harvard Stem Cell Institute Active in clinical translation, his work bridges molecular cardiology with regenerative medicine and metabolic research, while maintaining significant advisory roles in major cardiovascular organizations.

Sinem Karamanمشاهده پروفایل

دانشیار

• Vascular Biology
• Genetic Engineering
• Obesity
• +۶ مورد دیگر

Sinem Karaman is an Academy Research Fellow and Docent in Cell and Molecular Biology at the University of Helsinki's Faculty of Medicine. She serves as Principal Investigator of the Organotypic Vasculature Lab and supervises doctoral programs in Integrative Life Science and Biomedicine. Education: B.Sc. and M.Sc. in Molecular Biology from Istanbul Technical University (2006, 2008), Ph.D. from ETH Zurich (2012), Docent (2018). Her research focuses on organ-specific blood and lymphatic vasculature in development and disease, with expertise in obesity, diabetes, and inflammation . She applies intravital imaging and single-cell RNA sequencing to study vascular leakage and lymphatic dysfunction. Recent work includes multi-omics analyses of lymphedema-induced adipose tissue , Notch-WNT crosstalk in melanoma metastasis , and VEGFR3 signaling in dural lymphatics . She has published extensively in journals like Nature Cardiovascular Research and Cell Reports Medicine . Scientific Awards: Academy Research Fellow (2020) Early Career Researcher (2018) Research Grant (2018) Travel Award for Poster (2018) She leads projects funded by the Sigrid Jusélius Foundation , Finska Läkaresällskapet , and Åland Foundations , focusing on lymphatic regulation in metabolic diseases and adipose tissue dysfunction . Her lab supervises doctoral theses and collaborates internationally.

• Neuroscience
• Lymphatic Biology
• Cardiovascular Research
• +۳ مورد دیگر

Salli Antila is a researcher at HUS Neurocenter, University of Helsinki, specializing in the intersection of lymphatic biology and neurological disorders. Her work bridges cardiovascular and neuroscience domains with a focus on molecular mechanisms. Her primary research investigates meningeal and dural lymphatic systems in brain pathology, particularly examining VEGF signaling pathways in Alzheimer's disease, stroke, and neuroinflammation. Recent studies demonstrate her expertise in vascular biology techniques including lymphatic vessel imaging, genetic manipulation of VEGF pathways, and analysis of neurodegenerative models. She explores critical questions about how lymphatic dysfunction contributes to amyloid pathology and stroke outcomes. Analysis of her 2023-2024 publications reveals a concentrated focus on dural/meningeal lymphatics, with consistent use of transgenic mouse models and molecular profiling. Her work challenges assumptions about lymphatic-amyloid interactions in Alzheimer's while establishing new connections between VEGF-C signaling and stroke recovery. Antila operates within Kari Alitalo's renowned research ecosystem at the University of Helsinki, evidenced by co-authorship on all recent publications. Her collaborative network spans neuroscience, immunology, and cardiovascular research groups across European institutions, though specific lab leadership roles aren't documented in the provided text.

Harri Nurmiمشاهده پروفایل

پژوهشگر

• Biomedicine
• Genetics
• Developmental Biology
• +۴ مورد دیگر

Harri Nurmi is a researcher affiliated with the University of Helsinki 's Department of Biomedicine within the Faculty of Medicine. His work spans interdisciplinary areas including biomedicine, physiology, and developmental biology, with a focus on vascular and lymphatic systems in diverse pathological contexts. Key Research Areas : Biomedicine, Genetics, Developmental Biology, Physiology, Immunology, Cardiovascular Research Publications reveal a sustained focus on lymphatic vessel dynamics (e.g., meningeal and dermal networks), neuroinflammation in Alzheimer's disease, cardiovascular complications in hypertension, and immunological responses in allergic airway inflammation. His collaborative studies often intersect with lymphatic signaling pathways (VEGF/VEGFR) and their roles in disease progression. Collaborations include prominent researchers like Kari Alitalo, Eero Mervaala, and Tanja Kivela, with affiliations to institutions such as the University of Helsinki and University of Chicago. His research outputs are frequently published in high-impact journals like Nature Cardiovascular Research , Science Immunology , and Nature Communications .

David Paniaguaمشاهده پروفایل

استادیار

• Interventional Cardiology
• Coronary Stents
• Structural Heart Disease
• +۳ مورد دیگر

David Paniagua, M.D. is an Assistant Professor at Baylor College of Medicine, affiliated with the Veterans Affairs Medical Center in Houston. His expertise lies in interventional cardiology, coronary stents, structural heart disease, and percutaneous heart valve procedures. He holds an M.D. from the University of Costa Rica and completed advanced training at Baylor College of Medicine, Mount Sinai Medical Center, and Japan's National Cardiovascular Center. Dr. Paniagua's research focuses on innovative cardiovascular interventions, including the world's first retrograde percutaneous heart valve implantation. His work spans both clinical and basic science domains, such as lymphatic venom transport and computational modeling of hemodynamics in cardiac devices. Awards: Pioneered the first retrograde percutaneous aortic valve implantation in humans. Labs/Teams: Contributed to the development of transcatheter aortic valve programs and heart valve teams at VA facilities. Grants: While specific grants are not listed, his publications indicate active research collaboration in cardiovascular innovation.

• Mucosal Immunology
• Anatomy of the Eye
• Cell Biology of the Pancreas
• +۳ مورد دیگر

Eugenio Bertelli is an Associate Professor of Human Anatomy at the University of Siena since 2002. He holds editorial board roles at J Histochem Cytochem , J Mol Histol , and Anat Cell Biol . His teaching spans Human Anatomy courses for Biological Sciences, Pharmacy, Ophthalmology, and Surgical Specialties. Bertelli’s research focuses on mucosal immunology, pancreatic cell biology, ocular anatomy, and vascular anatomy. Key contributions include studies on pancreatic islet-ductal interactions, M-cell antigen transport, and Salmonella-induced immune responses. His work bridges histology, clinical anatomy, and immunopathology. Recent publications explore anatomical variations, hepatic steatosis mechanisms, and epiretinal membrane biology. He has authored textbooks like Atlante Fotografico Anatomia Macroscopica . Education: MD, University of Siena (1988) PhD in Morphological Sciences (1996) Postdoctoral Fellowships at Université de Montréal (1995-1997) and University of Siena (1997-1998) Research Interests: Mucosal Immunology: Focus on M-cells, antigen transport, and gut immunity Pancreatic Cell Biology: Endocrine-exocrine interactions, islet-ductal relationships Ocular Anatomy: Retinal pathologies, epiretinal membrane composition Vascular Anatomical Variations: Clinical implications in surgery and imaging Recent Research Trends: His articles emphasize anatomical variation documentation (e.g., temporal arteries, ethmoidal foramina), experimental models of metabolic disease (liver steatosis), and translational studies on epiretinal membrane proteins. Collaborations include investigations into Salmonella pathogenesis and lymphatic dysfunction in lymphedema. Professional Activities: Active in anatomical education, editorial work, and clinical-anatomical interface research. No grants/advising details explicitly reported in sources.

Kathleen Caronمشاهده پروفایل

استاد

• Cardiovascular Development
• G Protein-Coupled Receptors
• Cardiovascular Physiology
• +۳ مورد دیگر

Kathleen Caron is a Professor and Chair of the Department of Cell Biology & Physiology at the University of North Carolina School of Medicine. She holds additional appointments in the Department of Genetics and is affiliated with the McAllister Heart Institute, Lineberger Comprehensive Cancer Center, and other interdisciplinary programs. Her research focuses on G protein-coupled receptor (GPCR) signaling pathways critical to cardiovascular development and disease, particularly the roles of RAMP proteins and adrenomedullin in lymphatic and vascular physiology. Her work integrates gene-targeted animal models with cell biological systems to uncover mechanisms underlying cardiovascular dysfunction. Notable achievements include discovering fundamental roles for secretin- and chemokine-family receptors in cardiovascular health, and elucidating RAMP-receptor interactions that govern lymphatic vessel formation and function. Dr. Caron received the 2019 OGE Best Mentor Award for her dedication to student development. Current research emphasizes adrenomedullin’s role as a prognostic marker in diseases like preeclampsia and its therapeutic potential in cardiovascular conditions. Her lab’s publications reflect interdisciplinary approaches to understanding vascular biology, with recent studies exploring lymphatic signaling in migraine, pregnancy-related cardiac remodeling, and environmental toxin impacts on development. Dr. Caron leads a collaborative lab within the UNC Genetics and Cell Biology curricula, fostering translational research at the intersection of physiology, genetics, and disease. Her affiliations span multiple centers, reflecting her broad impact in cardiovascular and cancer research.

Reid Landesمشاهده پروفایل

استاد

• Biostatistics
• Radiation Effects on Health
• Statistical Methods for Dose-response Analysis
• +۵ مورد دیگر

Reid Landes, Ph.D., is a Professor in the Department of Biostatistics at the Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences (UAMS). He specializes in biostatistical methodologies with a focus on radiation effects, dose-response analysis, and public health research. His work spans clinical trials, animal studies, and epidemiological analyses. Education: Ph.D. in Statistics, Iowa State University (2005) MS in Biometry, University of Nebraska (1999) BSE in Mathematics, Southern Arkansas University (1994) Dr. Landes' research interests include power and sample size calculations, statistical methods for evaluating radiation exposure risks, neuroeconomics discounting models, and hierarchical modeling. He has contributed to studies on atomic bomb survivors' radiation effects, cardiovascular responses to ionizing radiation, and pediatric obesity mechanisms. His recent publications emphasize interdisciplinary collaborations, such as analyzing lymphatic dysfunction in hypertension, evaluating campus writing programs, and bridging healthcare gaps for Parkinson's disease patients in rural areas. Methodologically, he addresses challenges like cage effects in animal studies and correction of statistical biases in regression analyses. Dr. Landes' work bridges statistical rigor with practical health applications, addressing both clinical and public health challenges.

• Neuroimmunology
• Multiple Sclerosis
• Neurodegeneration
• +۲ مورد دیگر

Fredrik Piehl is Professor of Neurology at Karolinska Institutet's Department of Clinical Neuroscience, where he leads the research group 'Inflammation and neurodegeneration after neurotrauma'. His research focuses on neuroinflammatory conditions including multiple sclerosis (MS) and myasthenia gravis (MG), with emphasis on B-cell mechanisms, biomarker development, and optimizing immunotherapies. The group's clinical-translational approach combines experimental immunology, epidemiological methods, and clinical trials to improve treatment outcomes. Research spans: Pathogenic B-cell/T-cell interactions in MS Neurodegeneration biomarkers (neurofilament light, GFAP) Rituximab therapy mechanisms in MS/MG Kynurenine pathway in viral neuroinflammation Real-world treatment effectiveness and safety Recent publications demonstrate strong focus on: Personalized treatment algorithms using serum biomarkers Multi-national registry studies on disease burden Immunometabolic dysregulation in neurological infections Novel mechanisms of meningeal lymphatic function Publications show consistent themes in neuroimmunology, biomarker validation, and treatment optimization across 300+ articles. Leads a 20+ member team including 11 PhD students investigating neuroimmunology, clinical trial design, and biomarker discovery. The group actively collaborates with international consortia and has significantly influenced MS treatment paradigms in Sweden.

Kumar Sambamurtiمشاهده پروفایل

استاد

• Alzheimer Disease
• Down Syndrome
• Sensory degeneration
• +۷ مورد دیگر

Kumar Sambamurti is a tenured Professor in the Department of Neuroscience at the Medical University of South Carolina (MUSC). He holds a PhD and serves as Co-Director of the Carroll A. Campbell, Jr. Neuropathology Laboratory. His research focuses on Alzheimer’s Disease (AD), Down Syndrome, and mechanisms of neurodegeneration, with an emphasis on Amyloid Precursor Protein (APP) processing and Aβ peptide regulation. He has extensively studied APP biology, γ-secretase function, and Aβ clearance pathways, including novel mechanisms involving low-dose γ-secretase inhibitors and environmental factors like homocysteine. Education: Ph.D. in Biochemistry (not explicitly stated, inferred from academic role). Key Positions: Tenured Professor, MUSC; Co-Director, Neuropathology Laboratory; Collaborator on mouse models with Dr. Granholm. His research interests include neuroinflammation, cholesterol’s role in AD, and dietary interventions (e.g., vitamin D3, GLP-1 agonists). He has developed biomarker measurement techniques and collaborated on drug candidates like Posiphen and melatonin therapies. His lab investigates γ-secretase regulation, APP turnover, and Aβ clearance via lymphatic pathways. He has trained over 9 postdoctoral fellows, graduated one Ph.D. student, and mentored multiple master’s students and co-Ph.D. candidates. Recent work explores gut-brain axis interactions, indole mediators, and sex-specific β-secretase regulation. His articles highlight neuroprotective strategies, including DPP-4 inhibitors for Parkinson’s and T cell dysfunction in neurodegeneration. Grants & Collaborations: Active grants on Aβ clearance mechanisms, neuroinflammation resolution, and drug development. Collaborates with Drs. Greig, Pappolla, and Lahiri on drug targets and biomarkers. Labs/Teams: Leads a lab focused on molecular biology, protein biochemistry, and mouse model studies. Maintains cutting-edge analytical methods for AD biomarkers and neuropathology assessments.

Antoine Louveauمشاهده پروفایل

استادیار

• Neuroscience
• Neuroimmunology
• Meningeal Lymphatics
• +۴ مورد دیگر

Dr. Antoine Louveau is an Assistant Professor of Molecular Medicine at the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University (CCLCM-CWRU), where he serves as Principal Investigator of the Louveau Laboratory within the Lerner Research Institute. His research focuses on the critical interface between the brain and immune system, specifically investigating the role of meningeal lymphatic vessels in normal and pathological brain function. Dr. Louveau's research interests span multiple areas of neuroimmunology and neuroscience: Meningeal lymphatic system and its role in CNS immunity Neuroimmune interactions in neurological disorders Alzheimer's disease and multiple sclerosis pathogenesis Brain barriers and immune cell trafficking Neuroinflammation and therapeutic interventions His laboratory has made significant contributions to understanding how meningeal lymphatic vessels regulate CNS drainage and immune responses. Dr. Louveau's research has revealed connections between meningeal lymphatic dysfunction and neurological disorders including Alzheimer's disease and multiple sclerosis. His team has demonstrated how meningeal lymphatics impact microglial responses and the efficacy of immunotherapies for neurodegenerative conditions. Analysis of his publication record shows consistent focus on meningeal lymphatic structure, function, and therapeutic potential across neurological conditions. Dr. Louveau has received recognition as a "CIMER Trained Mentor," indicating completion of specialized mentorship training aimed at advancing mentoring relationships and promoting cultural change in research. As a principal investigator, Dr. Louveau mentors several trainees including postdoctoral fellows, graduate students, and undergraduate research students. His laboratory collaborates extensively with other researchers at Cleveland Clinic and beyond to investigate the complex relationships between the nervous and immune systems. The Louveau Laboratory is part of the Lerner Research Institute at Cleveland Clinic, a premier biomedical research institution that provides state-of-the-art facilities and resources for cutting-edge neuroscience research.

• Tissue Engineering
• Plastic Surgery
• Regenerative Medicine
• +۴ مورد دیگر

Wayne Morrison serves as an Adjunct Professor in the School of Behavioural and Health Sciences within the Faculty of Health Sciences. His academic career spans decades of innovation in tissue engineering and reconstructive surgery, with a focus on translating laboratory discoveries into clinical applications for tissue regeneration and defect repair. Dr. Morrison's research program centers on vascularization strategies for engineered tissues, adipose stem cell applications, and liver bioengineering. His pioneering work on the vascularized tissue engineering chamber model has revolutionized approaches to creating functional tissue flaps and organoids. Key investigations include the role of macrophages in adipogenesis, development of iPSC-derived vascular networks, and novel methods for enhancing fat graft survival through anti-inflammatory interventions. Analysis of his publication trajectory reveals consistent advancement in vascularized tissue engineering, with recent emphasis on liver regeneration using iPSC technologies and lymphatic network reconstruction. His collaborative work demonstrates integration of biomaterials science, stem cell biology, and microsurgical techniques to address complex tissue defects. The 2024 publication on liver specification represents the culmination of years of research toward functional organ engineering. Dr. Morrison has significantly contributed to surgical knowledge through book chapters on pharyngeal reconstruction, digital replantation, and foundational plastic surgery techniques. His research group maintains strong collaborations with tissue engineering specialists and clinical surgeons across Australia, focusing on solutions for radiation injury, traumatic defects, and organ failure. The vascularized chamber model remains central to ongoing investigations in vascularized tissue generation and in vivo bioreactor applications.

Bo Zhuمشاهده پروفایل

پژوهشگر ارشد

• Vascular Biology
• Atherosclerosis
• Lymphatic System
• +۴ مورد دیگر

Bo Zhu is a Research Fellow specializing in vascular biology, atherosclerosis, lymphatic system development, and computational approaches to single-cell analysis. His work bridges experimental biology and machine learning to investigate molecular mechanisms in vascular diseases, immune responses, and tissue repair processes. His primary research domains include: Vascular Biology and Endothelial Cell Function Atherosclerosis and Foam Cell Formation Lymphatic System Development and Valve Formation Single-Cell Genomics and Computational Biology Diabetic Wound Healing Mechanisms Metabolite-Mediated Intercellular Communication Oxidative Stress in Metabolic Disorders Recent publications demonstrate a strong focus on chemokine signaling (CXCR4/CXCL12), epsin-mediated regulation in macrophages, S1PR1-dependent lymphatic development, and machine learning applications for cell identity gene discovery. His interdisciplinary approach combines wet-lab experimentation with bioinformatics to address complex questions in vascular pathophysiology, with emerging work on neuro-lymphatic communication and metabolite signaling networks. No scientific awards were documented in the available information. There is no evidence of student advising or research grant management in the current records. His work appears to be conducted within collaborative research teams focused on vascular biology and computational genomics, though specific laboratory affiliations or team structures remain unreported in the provided materials.