جست‌وجوی استاد و پژوهشگر

Johann Bauersachsمشاهده پروفایل

استاد

• Acute and chronic heart failure
• Acute coronary syndromes
• Aldosterone and mineralocorticoid receptor-mediated mechanisms
• +۴ مورد دیگر

Professor Johann Bauersachs serves as Full Professor and Director of the Department of Cardiology and Angiology at Hannover Medical School (MHH) since 2010, with a distinguished career in cardiovascular research and clinical cardiology. He is a Fellow of the American Heart Association, European Society of Cardiology, and Heart Failure Association, and holds leadership positions including Chair of the HFA Committee on Peripartum Cardiomyopathies and Spokesperson of the DFG-funded Clinical Research Group KFO 311. His primary research interests focus on acute and chronic heart failure , acute coronary syndromes , left ventricular healing and remodeling , and the pathophysiology and treatment of peripartum cardiomyopathy . His work particularly emphasizes aldosterone and mineralocorticoid receptor-mediated mechanisms and the role of non-coding RNAs in cardiovascular disease. With over 1,133 publications and impressive H-indices (107 in Web of Science, 135 in Google Scholar), his recent research has centered on microRNA-based therapies like the HF-REVERT trial with CDR132L and the DIGIT-HF study investigating digitoxin for advanced heart failure. His most recent publications (2023-2024) demonstrate a clear trajectory toward translational research bridging molecular mechanisms with clinical applications, particularly in heart failure management. Key themes include the synergistic effects of SGLT2 inhibitors with mineralocorticoid receptor antagonists, novel therapeutic approaches for peripartum cardiomyopathy, and innovative diagnostic and treatment strategies for heart failure with preserved ejection fraction. Highly cited researcher in Clinical Medicine (Clarivate, 2023) ScholarGPS Highly Ranked Scholar (2022) Silver Badge of Honour, German Cardiac Society (2021) Paul-Morawitz-Award, German Cardiac Society (2018) Bernard and Joan Marshall Distinguished Investigator Award (2012) Parmley-Award, American College of Cardiology (2006) As Principal Investigator of multiple clinical trials including HF-REVERT and DIGIT-HF, Professor Bauersachs has secured significant funding from organizations including the Deutsche Forschungsgemeinschaft (DFG) and the Federal Ministry of Education and Research. His laboratory at MHH (Building I3) focuses on cardiac wound healing and remodeling after ischemia, with particular emphasis on mineralocorticoid receptor function in myeloid cells. He also serves in editorial capacities including Deputy Editor of the European Heart Journal and Associate Editor of Cardiovascular Research, while maintaining active advisory roles with Cardior Pharmaceuticals and Heartbeat.bio.

Gioacchino Natoliمشاهده پروفایل

استاد

• Transcription
• Epigenetics
• Innate Immunity
• +۳ مورد دیگر

Gioacchino Natoli is a Professor of Biochemistry at Humanitas University, School of Medicine, Milan, and serves as a Group Leader at the European Institute of Oncology (IEO) where he heads the Transcriptional Control in Inflammation and Cancer research program. Elected to the Academy of Europe in 2017 and an EMBO member since 2013, his work bridges molecular oncology and immunology with significant contributions to epigenetic regulation. Education: Medical Doctor with honors, University of Rome, La Sapienza (1991) Residency in Internal Medicine, University of Rome, La Sapienza (1991-1996) Post-doctoral fellow, University of California San Diego under Prof. Michael Karin (1998-2000) His research centers on transcriptional and epigenetic mechanisms governing innate immunity and cancer, with specific expertise in macrophage biology, chromatin dynamics, and non-coding transcription. He investigates how enhancers and cis-regulatory elements control inflammatory gene expression programs and maintain cellular identity in tumorigenesis, employing genomic and biochemical approaches to dissect disease-relevant pathways. Analysis of his publication record reveals consistent focus on epigenetic control of inflammation-cancer crosstalk, with landmark studies on histone modifiers (Jmjd3, Mll4) and enhancer functionality published in Nature Immunology, Cell, and Molecular Cell. His work demonstrates how environmental signals are integrated at genomic loci to shape immune responses. Scientific Awards: European Research Council (ERC) Advanced Grant (2016-2021) EMBO member (2013) European Research Council (ERC) Advanced Grant (2011-2015) Chiara D’Onofrio prize for Italian researchers below 43 years (2009) Marie Curie Excellence Grant (2007-2010) Damon Runyon-Walter Winchell Cancer Research Fund Long Term Fellowship (1998-2000) Natoli has secured substantial competitive funding including dual ERC Advanced Grants to investigate transcriptional networks linking inflammation and cancer. His laboratory at IEO mentors doctoral candidates and postdoctoral researchers, fostering expertise in genomic technologies and molecular pathogenesis while advancing therapeutic target discovery. He leads the Transcriptional Control in Inflammation and Cancer program within IEO's research infrastructure, utilizing advanced sequencing and imaging platforms to map regulatory landscapes in disease models. The group collaborates extensively with clinical teams to translate mechanistic insights into oncology applications.

Irene Bozzoniمشاهده پروفایل

استاد

• Non-coding RNA
• Gene Expression Regulation
• Long Non-coding RNA
• +۳ مورد دیگر

Irene Bozzoni serves as Full Professor of Molecular Biology at Sapienza University of Rome, a position held continuously since 1994 following her promotion from Associate Professor (1986-1994). Her academic career began with research appointments at Rome's Center for Nucleic Acid Research (CNR) and a post-doctoral fellowship at University of Zurich's Institute of Molecular Biology. Her research expertise centers on non-coding RNA mechanisms with specific focus: Mechanism and regulation of non-coding RNA function in mammalian cells Role of non-coding RNA in gene expression control Long non-coding RNA biology Therapeutic RNA applications This work bridges molecular and cellular biology, advancing understanding of RNA-mediated genetic regulation. Her contributions have earned significant recognition: Accademia Nazionale dei Lincei Prizes (2003, 2006) Sapienza Ricerca Award (2010) Membership in European Molecular Biology Organization (EMBO) Membership in Academia Europaea As an ordinary member of the Academy of Europe's CELL & DEVELOPMENTAL BIOLOGY section since 2002, she maintains active engagement in international scientific discourse while continuing her research leadership at Sapienza University.

• Microbiology
• Genetics and Molecular Biology
• RNA Biology
• +۳ مورد دیگر

Dr. Benjamin Coltman is an active researcher affiliated with the Centre for Microbiology and Environmental Systems Science and the Department of Microbiology and Ecosystem Science . His work focuses on molecular biology, genomics, and RNA sequencing, with particular emphasis on long non-coding RNAs (lncRNAs) in yeast biotechnology. Research Areas: Genetics and molecular biology, RNA sequencing, microbial systems science, bioinformatics, and biotechnology applications. Recent Publication: Lead author on a 2025 Computational and Structural Biotechnology Journal article analyzing lncRNA functionality in Komagataella phaffii . Collaborations: Engaged in external collaborations across academic institutions, focusing on microbial genomics and biotechnological applications.

• Bioinformatics
• Genomics
• Cancer Research
• +۵ مورد دیگر

Leila Taher is a researcher at the Institute of Biomedical Informatics, TU Graz. Her work focuses on integrating computational methods with genomic data to study cancer biology, epigenetic regulation, and comparative oncology. She has developed tools like T3E and DNA-DDA for analyzing transposable elements and 3D chromatin structure. Her research spans canine and feline cancer models, immune mechanisms, and functional genomics. Key projects include designing targeted NGS panels for canine lymphoma and exploring synergistic drug combinations for B-cell lymphoma. Her interdisciplinary approach bridges bioinformatics, veterinary medicine, and human health. Education and affiliations are not explicitly detailed in the text, but her long-term contributions to genomics (publications span 2003–2024) suggest advanced academic training. Collaborations involve molecular biology, computational biology, and clinical oncology teams. She leads research in areas such as chromatin architecture prediction, enhancer function, and immune cell regulation. Her lab's tools have been applied to study autoimmune diseases, developmental biology, and translational medicine. Research themes include: (1) Developing algorithms for genomic analysis, (2) Investigating epigenetic mechanisms in cancer, (3) Translating canine models to human oncology, and (4) Exploring gene regulatory networks in development. Recent work emphasizes reproducibility in NGS pipelines and the role of repetitive elements in functional genomics.

Andrea Tanzerمشاهده پروفایل

پژوهشگر

• RNA Biology
• Transcriptomics
• Non-Coding RNA
• +۴ مورد دیگر

Andrea Tanzer is a researcher at the Max Perutz Labs, Department of Biochemistry and Cell Biology. Her work focuses on RNA biology, particularly RNA structure and function, non-coding RNA, and bioinformatics tools for genomic analysis. She leads the RNALands project (2015–2019), developing methods for RNA folding landscape analysis. Her research contributes to understanding RNA editing mechanisms, epigenetic regulation, and host-pathogen interactions. Key research interests include RNA structure prediction, transcriptome-wide analyses, and the role of RNA modifications in gene regulation. Tanzer has presented on topics such as RNA bioinformatics, structureomics, and G-quadruplexes in RNA. Her work bridges computational methods and experimental biology, with applications in both fundamental science and biomedical diagnostics. Notable contributions include the RNAxplorer tool for RNA structure sampling and collaborations on the GENCODE project. Media highlights include coverage of her work on mouse genome applications for human diagnostics.

Bozzoni Ireneمشاهده پروفایل

استاد

• Mechanism and regulation of non coding RNA function in mammalian cells
• Role of non coding RNA in gene expression control
• Long non coding RNA
• +۱ مورد دیگر

Irene Bozzoni is a Full Professor of Molecular Biology at the University of Rome, specializing in non-coding RNA research. Her work explores the regulatory mechanisms of non-coding RNA in mammalian cells, their role in gene expression control, and their therapeutic applications in diseases like Duchenne Muscular Dystrophy. Current: Full Professor of Molecular Biology, University of Rome Past: Associate Professor (1986-1994), Staff Scientist (1980-1986), Research Fellow (1978-1980) at CNR, Rome Her research focuses on long non-coding RNAs, microRNA biogenesis, and RNA-based therapies. Publications highlight RNA-gene interactions, muscle differentiation, and molecular circuitries in diseases. Scientific honors include Accademia Nazionale dei Lincei Prizes (2003, 2006), the Sapienza Ricerca Award (2010), and memberships in EMBO and Academia Europaea.

• RNA binding proteins
• Epigenetics
• Root architecture
• +۵ مورد دیگر

Martin Crespi is a CNRS Researcher at the Institute of Plant Sciences Paris-Saclay (IPS2) since 2018 and has led the "Regulatory RNAs in root plasticity" team since 2003. He served as Director of IPS2 (2015-2024), Director of the Plant Genomics Unit (2014-2015), and held leadership roles at CNRS institutions since 1994. Current Position: Researcher, CNRS, IPS2 Leadership: 14-member team (7 permanent) His research focuses on non-coding RNAs, epigenetics, and root development, exploring how riboregulators interact with splicing/chromatin factors to modulate root adaptability. His work bridges plant molecular biology, symbiosis, and environmental stress responses. Recent publications highlight his contributions to understanding RNA-mediated regulation in Arabidopsis and Medicago truncatula, covering topics like alternative splicing, chromatin looping, and miRNAome plasticity. These studies integrate genomics and molecular biology to decode root-soil interactions. Scientific Awards: Prix Dr. Pedro Berdoy (Argentina), National Society of Experimental Biology Award (Argentina) He has supervised 18 PhD students, 43 postdocs, and 14 Masters while leading 61 projects (including 9 EU grants and 7 Marie Curie grants) and participating in over 30 international scientific committees or review panels.

• Molecular Biology
• Biochemistry
• Cell Biology
• +۶ مورد دیگر

Eleonora Candi is a Full Professor in Molecular Biology at the Department of Experimental Medicine, University of Rome Tor Vergata, and Head of the Biochemistry laboratory at IDI-IRCCS hospital in Rome, Italy. Her research focuses on epithelial development, programmed cell death (apoptosis), and the roles of p63, microRNAs, and long non-coding RNAs in skin biology and squamous cell carcinomas. PhD (1995, Rome) in Skin Biochemistry BSc (1991, Rome) in Biology Her expertise spans epithelial differentiation, cancer epigenetics, and transgenic mouse models. She previously held roles as Assistant and Associate Professor at the same university, with fellowships at NIAMS-NIH (USA) and European laboratories. Her editorial roles include Editor-in-Chief of Discover Oncology and membership on multiple journal editorial boards. Alternate of the Shadow Committee for Horizon Europe (2019–2020) Telethon Research Fellow (1999–2001) ECDO Academy Member (2012–present) Dr. Candi has contributed to 158 scientific articles with an H-index of 53, focusing on p63's oncogenic roles and epigenetic regulation in epithelial cancers. She uses biochemical, molecular, and animal model approaches to study cancer cell fate and therapeutic strategies.

• RNA Biology
• RNA Synthesis
• RNA Degradation
• +۴ مورد دیگر

David Tollervey is a Professor of RNA Biology and Wellcome Principal Research Fellow at the Wellcome Centre for Cell Biology , University of Edinburgh. He has held this position since 1997 and served as Director of the Centre from 2011 to 2021. His academic journey includes postdoctoral training at UC San Francisco and a PhD in Genetics from the University of Cambridge. Research Interests: Tollervey specializes in RNA biology, focusing on RNA synthesis, degradation, and surveillance mechanisms. His work explores ribosome synthesis, non-coding RNAs in disease, and the interplay between RNA and protein synthesis. Key contributions include defining exosome function and RNA interactome mapping. Education: BSc (Hons) in Microbiology, University of Edinburgh (1973–1977) PhD in Genetics, University of Cambridge (1977–1980) Awards & Honours: Fellow of the Royal Society (2004) President of the RNA Society (2007–2008) Biochemical Society Novartis Medal (2016) Fellow of the Academy of Medical Sciences (2022) Labs & Teams: Leads the RNA Biology group at the Wellcome Centre, focusing on mechanistic and functional studies of RNA processing. Collaborates extensively with global research networks.

• Molecular Biotechnology
• Cellular Senescence
• Aging and Gerontology
• +۱۰ مورد دیگر

Johannes Grillari is Associate Professor at the Institute of Molecular Biotechnology, Department of Biotechnology and Food Science, University of Natural Resources and Life Sciences, Vienna (BOKU), and Director of the Ludwig Boltzmann Institute for Traumatology in collaboration with AUVA. His research bridges molecular biotechnology, aging, and regenerative medicine, with a focus on extracellular vesicles (EVs) and microRNAs in cellular senescence and tissue regeneration. Research Interests: Molecular mechanisms of cellular and organismal aging Role of miRNAs and EVs in senescence and regeneration Targeted delivery of EVs for regenerative medicine Discovery of biomarkers for aging and age-related diseases Senolytic therapies and ribosomal heterogeneity in aging His work has pioneered the understanding that EVs from senescent cells inhibit regeneration, whereas those from mesenchymal stromal cells have therapeutic potential. He has authored over 230 SCI publications and holds 15 patents, with recent research focusing on engineered EVs, EV-based diagnostics, and senolytic drug development. Scientific Awards: Walter Doberauer Prize for Aging Research (2012) Best Presentation Award, telomerase: a crystal ball for the future? (2011) Poster Prize at ECONAG 2006 Poster Prize at EMBO/Harden Conference 2004 Advising, Grants, and Leadership: Johannes Grillari leads multiple research projects funded by the Christian Doppler Research Society and the Austrian Science Fund (FWF), including the CD Laboratory for Multimodal Analytical Imaging of Skin Aging and Senescence. He is a co-founder of biotech companies in the field of senescence and EVs, and actively mentors students and early-career researchers. Labs and Research Teams: His research is conducted at the Institute of Molecular Biotechnology at BOKU and the Ludwig Boltzmann Institute for Traumatology. His team focuses on EV biology, miRNA signaling, skin and bone aging, and the development of novel therapeutic and diagnostic tools.

Tartaglia Gian Gaetanoمشاهده پروفایل

استاد

• Molecular Biology
• RNA Interactions
• Biochemistry of Phase Separation
• +۷ مورد دیگر

Gian Gaetano Tartaglia is a Full Professor of Biochemistry at the University of Rome La Sapienza and Senior Group Leader at the Italian Institute of Technology (IIT) in Genoa. He holds tenured positions including ICREA Research Professor (Catalonia) and leads the RNA Systems Biology Lab. His research focuses on RNA interactions, phase-separated assemblies, and neurodegenerative diseases. Education: MPhil in Biophysics, University of Rome Sapienza (1996-2001) PhD in Biochemistry, University of Zurich (2001-2006) Post-Doc in Chemistry/Genetics, University of Cambridge (2005-2010) Research Interests: Molecular mechanisms of RNA-protein interactions, amyloid formation, systems biology approaches to neurodegenerative diseases (e.g., ALS, Alzheimer's), and bioinformatics tools like catRAPID for predicting RNA-binding proteins. Specializes in autogenous feedback loops and X-chromosome inactivation via long non-coding RNAs. Awards: ERC Synergy Grant (2020) ICREA Professorship (2014) Over 10,000 citations with h-index 58 (Google Scholar) Grants & Labs: Secured € multimillion grants including Target ALS (2023) and EIC Pathfinder. Leads teams developing algorithms for RNA-protein interaction prediction (e.g., catRAPID , PAnDA ). Holds a 2022 patent on aptamer design through IIT.

Eulàlia de Nadalمشاهده پروفایل

استاد

• Cellular Signaling
• Stress Responses
• Transcription Regulation
• +۳ مورد دیگر

Eulàlia de Nadal is the Rector of the University Pompeu Fabra (UPF, Barcelona) since 2023 and a Full Professor in the Department of Medicine and Life Sciences (MELIS). She has held leadership roles including Vice-rector for Knowledge Transfer (2021–2023) and Vice-director of the Department of Experimental and Health Sciences (2015–2019). She earned a Veterinary Medicine degree (UAB, 1995) and a Ph.D. in Biochemistry & Molecular Biology (UAB, 2000). Her research focuses on cellular signaling, stress responses, and transcription regulation, with a particular emphasis on genomic stability and cancer biology. Key research contributions include studies on histone modifications under stress, genomic integrity mechanisms, and RB protein regulation in cancer. She leads the Cell Signaling group at UPF and is an Affiliated Group Leader at IRB Barcelona. Her work has been supported by 6 Spanish Government grants and multiple international collaborations. She has published 54 original articles (43 in the last decade) with an h-index of 34. Awards : Two ICREA Acadèmia Awards (2012–2016 & 2021–2025), Special Doctoral Thesis Award (2001). Advising : Co-supervised 14 doctoral theses and currently supervises 5 pre-doctoral students. Grants : Principal investigator of 6 national projects (2005–2023); collaborations with EU, Catalan Government, and private entities. Her lab integrates epigenetic, genomic, and proteomic approaches to study stress signaling pathways and their translational impact on health and disease.

Fátima Gebauerمشاهده پروفایل

پژوهشگر

• mRNA translation
• Post-transcriptional regulation
• RNA binding proteins
• +۲ مورد دیگر

Dr. Fátima Gebauer is a Group Leader at the Centre for Genomic Regulation (CRG) in Barcelona, Spain, since 2002. Her research focuses on RNA-binding proteins and their role in translational control , particularly in cancer progression and Drosophila development . She leads a research team studying how RNA networks maintain cell homeostasis and how their deregulation contributes to diseases like melanoma. PhD in Biological Sciences (1990) from the Department of Biochemistry and Molecular Biology, Autónoma University of Madrid Postdoctoral training at Worcester Foundation for Biomedical Research (1992-1996), EMBL (1996-2000) Her research bridges post-transcriptional regulation and oncogenesis , targeting mechanisms like mRNA translation and RNA networks in melanoma metastasis. Current projects include exploring RNA-based therapeutics for brain disorders funded by the BIST Ignite Grant. Scientific awards include: EMBO Membership (2017) Ramón y Cajal Award (2002) Marie Curie Postdoctoral Fellowship (1996) Spanish Ministry of Science Postdoctoral Fellowship (1993) NATO Postdoctoral Fellowship (1992) Spanish Ministry of Science PhD Fellowship (1987) Her lab at CRG collaborates with institutions like the Institute for Bioengineering of Catalonia (IBEC) and receives funding from organizations such as the Spanish Ministry of Economy and Innovation, AGAUR, La Caixa Foundation, and the Melanoma Research Alliance.

• Cardiovascular Disease
• Non-coding RNAs
• Molecular Biology
• +۴ مورد دیگر

Li Peifeng is a distinguished Professor and Dean at the Institute of Translational Medicine, College of Medicine, Qingdao University, China. He also serves as Director of the Key Laboratory of Nucleic Acid Biology in Cardiovascular Disease (Shandong) and the International Research Centre for Non-coding RNAs and Translational Medicine (Qingdao). His academic career includes roles as Distinguished Professor at the Chinese Academy of Sciences (2006–2013) and a Medical Researcher at the Max-Delbrück-Center for Molecular Medicine in Berlin (1995–2005). Li Peifeng holds an MD and PhD from the Chinese Academy of Medical Science (1990–1993). His research focuses on cardiovascular biology, non-coding RNAs, and molecular mechanisms underlying myocardial infarction, heart failure, and apoptosis. He has led groundbreaking studies on miRNA regulation in cardiac pathologies and oxidative stress responses. Notable awards include the World’s Top 2% Scientists (2020), Highly Cited Chinese Researchers (2020), and multiple national and provincial accolades. He is an editorial board member for journals like Molecular Biotechnology and Circulation Research , and has reviewed grants for institutions including the European Research Council and the American Heart Association. Awards: Taishan Scholar (2018), Leading Innovative Scientist (2018), Tip-top Talent (2017). Leadership Roles: Organized major conferences, including the Annual Conference on Cell Biology (2018) and International Cardiology Conferences (2014–2015). Key Labs: Directs research centers focused on nucleic acid biology and non-coding RNAs in cardiovascular disease.