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نمایش ۱-۱۵ از ۱۳۰ استاد راهنما

اطلاعات پروفایل‌ها از صفحات عمومی دانشگاه‌ها گرفته شده و ممکن است به‌روز نباشد.

Hokyung Kay Chungمشاهده پروفایل

استادیار

University of North Carolina at Chapel HillUnited States

Hokyung Kay Chung, PhD is an Assistant Professor in the Department of Cell Biology and Physiology at the University of North Carolina at Chapel Hill School of Medicine and a member of the UNC Lineberger Comprehensive Cancer Center. Her research program integrates synthetic biology, immunology, and cancer biology to engineer T cells for enhanced anti-tumor efficacy. Dr. Chung's research focuses on harnessing synthetic biology to reprogram T cell differentiation states for cancer immunotherapy. Her laboratory employs protein engineering, next-generation sequencing, CRISPR screening, and bioinformatics to develop three core platforms: (1) Transcription factor recipes for T cell programming using multiomics atlas-based analysis and in vivo CRISPR screening; (2) Synthetic toolkits for designer immunity including drug-inducible transcription factor circuits and signal rewiring platforms; (3) Hijacking tumors via engineered oncolytic viruses to encode immune modulators. Her work aims to create context-specific cell state programming that enhances T cell therapy efficacy across diverse cancer types. Her publication portfolio demonstrates significant contributions to synthetic immunology, with high-impact papers in Science, Nature Chemical Biology, Cell, and Immunity covering protease-based control systems, T cell differentiation engineering, and tumor microenvironment remodeling. Recent work includes developing sonogenetic CAR-T cells controllable by ultrasound and elucidating metabolic mechanisms of T cell exhaustion. K01 Research Scientist Development Award, NIH, 2023 Keystone Symposia Future of Science Fund Scholarship, 2020 Damon Runyon Fellowship Award, 2019 Salk Women & Science Special Award, 2019 Hans Neurath Outstanding Promise Travel Award, 2017 Dr. Chung leads the Chung Lab at the UNC Lineberger Comprehensive Cancer Center, where she directs research on synthetic T cell engineering. Her lab utilizes advanced techniques including single-cell CRISPR screening, protein engineering, and oncolytic virology to develop next-generation immunotherapies. Current projects focus on creating artificial T cell differentiation pathways and engineering the tumor microenvironment to support persistent anti-tumor immunity.

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Sara Liinمشاهده پروفایل

دانشیار

Linköping UniversitySweden

Sara Liin is a Senior Associate Professor at Linköping University, affiliated with the Department of Biomedical and Clinical Sciences within the Faculty of Medicine and Health Sciences. Her research focuses on ion channel dysfunction in cardiac arrhythmias, particularly exploring polyunsaturated fatty acids and endocannabinoids as therapeutic avenues. She holds a PhD in Neurobiology (2011) and a Master in Medical Biology (2005). Her work emphasizes understanding how genetic mutations in cardiac ion channels lead to arrhythmias and developing targeted treatments. Recent studies highlight the role of estrogen in exacerbating arrhythmia risk and the potential of endocannabinoids like ARA-S to rescue mutant channels. Liin has secured grants totaling SEK 64 million and leads a research group investigating lipid-channel interactions and drug development strategies. Key achievements include the Eric K Fernström award (2021) and collaborative projects with institutions like the University of Miami and SciLifeLab. Her lab, part of the Division of Cell and Neurobiology, explores translational applications of ion channel research to combat heart rhythm disorders.

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Jaideep K. Malhotraمشاهده پروفایل

استادیار بالینی

Weill Cornell MedicineUnited States

Jaideep K. Malhotra, M.D., is an Assistant Professor of Clinical Anesthesiology at Weill Cornell Medical College, Cornell University, and an Assistant Attending Anesthesiologist at NewYork-Presbyterian Hospital. His clinical expertise focuses on Thoracic Anesthesia. He has been affiliated with Weill Cornell since 2011. Dr. Malhotra earned his B.A. from the University of Vermont (1994) and his M.D. from the Medical College of Wisconsin (1999). His research interests span anesthesiology, pharmacology, and cardiology, with a focus on neuromuscular blocking agents, cardiopulmonary effects, and cardiac electrophysiology. His work includes studies on novel drugs like CW002, preclinical safety evaluations, and molecular mechanisms in atrial tissue. His publications emphasize drug efficacy, pharmacodynamics, and translational research across human and animal models. No external relationships or reported awards are noted in the provided texts.

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Gregory Dickمشاهده پروفایل

استاد پژوهش

University of North Texas Health Science CenterUnited States

Gregory Dick, PhD, is a Research Professor in the Department of Physiology & Anatomy at the University of North Texas Health Science Center's College of Biomedical and Translational Sciences. His research focuses on ion channel regulation in coronary arteries, particularly how potassium channels control vascular tone under normal and pathological conditions (e.g., obesity, diabetes). He has led multiple NIH-funded projects exploring coronary vascular dysfunction and metabolic signaling. Education: Bachelor of Science in Physiology, Oklahoma State University Doctor of Philosophy in Physiology, University of Missouri Research Interests: Electro-metabolic signaling in coronary vasodilation Role of K+ channels in coronary blood flow regulation Impact of metabolic syndrome and obesity on cardiovascular health Vascular smooth muscle plasticity in disease states Key Projects (2024–2026): Role of potassium as a coronary metabolic vasodilator (Principal Investigator) Disentangling the Mechanisms of Coronary Dysfunction (Co-Investigator) Grants & Funding: NIH R01 Grant: Mineralocorticoid Receptor-Dependent Coronary Vascular Dysfunction in Obesity Multiple collaborative grants with University of Michigan and University of Missouri Collaborations: Active partnerships with institutions studying coronary autoregulation, metabolic syndrome, and swine models of cardiovascular disease.

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Nikita Kavokineمشاهده پروفایل

استادیار

Swiss Federal Institute of Technology in LausanneSwitzerland

Nikita Kavokine serves as Tenure Track Assistant Professor at École Polytechnique Fédérale de Lausanne (EPFL) within the School of Basic Sciences . His dual appointments span the Institute of Chemical Sciences and Engineering (ISIC) and the School of Chemical Sciences and Engineering (SCGC) , where he leads the Quantum Plumbing Lab (LNQ) and contributes to graduate teaching. Based at Building CH A2 398 in Lausanne, he maintains active research and instructional roles across EPFL's chemistry and chemical engineering programs. His research pioneers quantum nanofluidics and nanoscale transport phenomena , focusing on electron-ion coupling mechanisms in confined geometries. Key investigations include quantum friction in water-carbon interfaces, hydroelectric energy conversion through nanochannels, and plasmon-hydron resonances in two-dimensional materials. His work bridges condensed matter physics, electrochemistry, and fluid dynamics to develop fundamental principles for next-generation nanofluidic devices and quantum sensors. Analysis of his 15 most recent publications (2023-2025) reveals three dominant research thrusts: quantum-enhanced energy conversion (evident in hydroelectric drag and electron cooling studies), non-classical ion transport (including ionic Coulomb blockade and interaction confinement), and emergent quantum hydrodynamics (momentum tunneling, collective modes). These publications consistently integrate advanced numerical methods with nanoscale experimental systems, establishing new paradigms for solid-liquid quantum interactions. Kavokine currently supervises three PhD students: Gispert Peter , Lu Hao , and Rigaux Killian David . His teaching portfolio includes graduate courses in Statistical Mechanics for Chemistry and Nanofluidics , emphasizing theoretical frameworks for many-particle systems and nanoscale fluid dynamics. Research funding supports his laboratory's exploration of quantum effects in nanofluidic channels, though specific grant details are not provided in source materials. The Quantum Plumbing Lab (LNQ) operates at the forefront of nanoscale quantum transport research, utilizing advanced nanofabrication and characterization techniques to probe electron-ion coupling phenomena. The lab's interdisciplinary team combines expertise in quantum physics, electrochemistry, and fluid dynamics to investigate fundamental limits of energy conversion and transport at atomic scales, with particular focus on graphene-based systems and angstrom-scale confinement.

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Mary Collinsمشاهده پروفایل

استاد

University of SydneyAustralia

Professor Mary Collins is a Professor of Pharmaceutical Neuroscience at the University of Sydney , affiliated with the Sydney School of Medical Sciences . She serves as Interim Associate Dean, Research and Head of School . Member of the Centre for Drug Discovery Innovation Member of the Brain and Mind Centre Research Interests GABA Receptors : Focus on subtype-selective modulators, binding site identification, and roles in anxiety, sleep disorders, and epilepsy. Nicotinic Acetylcholine Receptors : Structure-function studies using site-directed mutagenesis and reactive probes to understand ligand binding. Drug Discovery : SAR studies for selective agents targeting Cys-loop receptors, including flavonoids and cannabinoids. Scientific Contributions Her 15 most recent articles (2020-2024) span epilepsy genetics , receptor stoichiometry , neuroprotective flavonoids , and cannabinoid interactions . Key themes include precision medicine for receptor variants and neurotransmitter modulation in disorders. ASCEPT Young Investigator Award RACI Biota Award Fellow of RACI (2006) Supervision Award (University of Sydney, 2008) Advising Current students: Jacinda HOLTSMARK (epilepsy neurophysiology), Sze Hon KAN (genetic epilepsies), Fiona WANG (neurological mechanisms).

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Antonios Pantazisمشاهده پروفایل

دانشیار

Linköping UniversitySweden

Antonios Pantazis is an Associate Professor and Docent at Linköping University, affiliated with the Department of Biomedical and Clinical Sciences (BKV) within the Faculty of Medicine and Health Sciences. He leads the Pantazis Laboratory of Cellular Excitability (PaLaCE), focusing on ion channel biophysics and their role in health and disease. His work integrates electrophysiological, optical, and computational methods to study ion channel structure-function relationships, particularly in cardiac and neuronal systems. Research interests include voltage-gated ion channels, cellular excitability, and the molecular mechanisms underlying arrhythmias and neurological disorders. Key contributions involve understanding mutations in genes like SCN5A and KCNA2, which are linked to epilepsy and cardiac arrhythmias. He has been awarded the Swedish Fernström Prize (2021) for his work on ion channels. Publications span topics such as ion channel regulation, molecular transitions in voltage-dependent processes, and drug targets for arrhythmia suppression. His laboratory also explores cutting-edge techniques like voltage-clamp fluorometry and optical methods to visualize protein dynamics. Collaborations include institutions like the Wallenberg Centre for Molecular Medicine (WCMM) at Linköping University, emphasizing translational research in medical technology and bioengineering.

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Jan de Hoonمشاهده پروفایل

استاد

KU LeuvenBelgium

Jan de Hoon serves as a full Professor at KU Leuven's Faculty of Medicine within the Department of Clinical Pharmacology and Pharmacotherapy. He holds dual leadership roles as Head of both the Subdivision and Division of Clinical Pharmacology, and is an active member of the Department of Pharmaceutical and Pharmacological Sciences. His institutional affiliations include membership on the Ethics Committee for Research at UZ/KU Leuven, the Council of the Faculty of Medicine, the POC Geneeskunde, and the Departmental Council. His research centers on TRP channel mechanisms in pain pathways and chemotherapy-induced peripheral neuropathy (CIPN), with significant translational focus from bench to bedside. Key projects include Targeting TRP channels to relief pain (2023-2027) and TRP - Tackling the Roots of Pain (2021-2025). His recent publications demonstrate expertise in neurovascular pharmacology, PET ligand development, and vascular biomarkers for TRP channel functionality. Analysis of his 2024-2025 publications reveals strong emphasis on TRP channel subtypes (TRPA1, TRPV1, TRPM3) in pain mechanisms, vascular readouts for drug effects, and translational models bridging preclinical findings to clinical applications in oncology and neurology. His work frequently employs human tissue studies, healthy volunteer trials, and cancer patient cohorts. As an academic leader, he supervises doctoral candidates including H. Marynissen (2024 thesis on TRP channels in CIPN) and contributes to medical education through courses in Pharmacology, Pharmaceutical Medicine, and Internal Medicine supplements. His research is supported by multiple active grants focusing on TRP channel therapeutics and biomarker development.

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Yijun Panمشاهده پروفایل

پژوهشگر ارشد

Monash UniversityAustralia

Yijun Pan is a Senior Research Fellow in the Department of Neuroscience at the Monash Institute of Pharmaceutical Sciences (MIPS), Monash University. He holds an adjunct lecturer position at Tohoku University, Japan. His research focuses on the role of Fatty Acid-Binding Proteins (FABPs) in immunometabolism and drug delivery in neurodegenerative diseases such as Alzheimer’s disease and Motor Neuron Disease. Bachelor of Pharmacy, Monash University PhD in Pharmaceutical Sciences, Monash University, supervised by Associate Professor Joseph Nicolazzo, Professor Christopher Porter, and Professor Martin Scanlon Dr Pan’s research interests center on the molecular mechanisms of FABPs in brain endothelial cells, microglia, and astrocytes, particularly in the context of neuroinflammation and lipid metabolism. His work explores how these proteins influence drug transport across the blood-brain barrier and contribute to disease progression in dementia and motor neuron disorders. He employs in vitro and in vivo models to study immunometabolic pathways and optimize therapeutic delivery. His recent publications demonstrate a strong trend in neuropharmacology, focusing on blood-brain barrier function, fatty acid transport, neuroinflammation, and cognitive outcomes in animal models. Key themes include the modulation of drug transporters, the role of ion channels in neuroprotection, and immune cell involvement in neurodegeneration. American Chemical Society Editors’ Choice Award, Molecular Pharmaceutics (2015) Best Oral Presentation Award, 8th Victorian Association of Chinese PhD Students and Young Scholars Research Symposium (2014) Honourable Geoffrey Connard AM Student Travelling Scholarship (2013) JSPS Postdoctoral Research Fellowship (2018) Neil Naismith Award (2012) Dr Pan is actively involved in mentoring and supervision, contributing to Honours and PhD projects at MIPS. He has served as a Chief Investigator on multiple competitive grants, including those from Dementia Australia and FightMND. He regularly engages in peer review for journals such as Molecular Pharmaceutics , Diagnosis , and Biomolecules , and has presented his work at institutions including RMIT and the National University of Singapore. He is a key member of the Drug Delivery, Disposition and Dynamics Theme at MIPS and collaborates internationally, particularly with Tohoku University. His research is supported by significant funding from the Japan Society for the Promotion of Science, Dementia Australia, and FightMND.

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Scott Chandlerمشاهده پروفایل

استاد

University of California, Los AngelesUnited States

Scott Chandler is a Professor in the Department of Integrative Biology and Physiology at the University of California, Los Angeles (UCLA). His research focuses on understanding the central nervous system's control of rhythmic movements and neurodegenerative diseases like ALS. B.S., Neurobiology, University of California, Berkeley Ph.D., Physiology/Neurophysiology, University of California, Los Angeles (1979) Chandler's research explores how small brainstem neuronal networks generate rhythmic movements (e.g., mastication, respiration) and how ion channels contribute to these processes. His lab investigates early ALS-related neuronal dysfunction using transgenic mouse models, aiming to identify molecular targets for drug therapies. 2023 study on GABA inhibition and L-type calcium currents in ALS mouse jaw neurons 2020 work on single-cell RNA-seq in ALS brainstem analysis 2019 publications on resurgent sodium currents and circuit-specific ALS impairments 2015 studies on sensory neuron enrichment and membrane homeostasis in ALS 2007-2009 work on Kv1 channels and Nav1.6 sodium currents in trigeminal neurons Chandler's lab combines electrophysiological recordings, computational modeling, and bioinformatics to unravel the cellular mechanisms underlying movement control and neurodegeneration.

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Timothy J. Lewisمشاهده پروفایل

استاد

University of California, DavisUnited States

Timothy J. Lewis is a Professor in the Department of Mathematics at the University of California, Davis, with a research focus on mathematical physiology, neurobiology, and excitable media. He has held positions at UC Davis since 2004, progressing from Assistant to Associate to Full Professor. Ph.D. in Mathematics (University of Utah, 1998) M.S. in Mathematics (University of Utah, 1993) M.Sc. in Physiology (McGill University, 1991) B.Sc. in Physiology and Physics (McGill University, 1988) His research interests include: Mathematical modeling of excitable media Neurobiology of electrically coupled neurons Cardiac electrophysiology and pharmacology Weakly coupled oscillator theory Dynamical systems in biological contexts His recent work spans computational neuroscience, cardiac drug interactions, and biomechanical systems. Key trends include: Modeling subcellular cAMP compartmentation Optimizing neurocardiac digital twins Analyzing sodium channel blocker efficacy Investigating spiral wave stability in excitable tissue Scientific awards include: 2011 G. Thomas Sallee Award for undergraduate teaching 2007 Galois Group Service Award He has mentored numerous graduate and undergraduate students, including: Jiawei Zhang (Ph.D. 2013, now at University of Arizona) Michael Schwemmer (Ph.D. 2010, now at Battelle Memorial Institute) Steffen Docken (current Ph.D. candidate)

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Tamir Gonenمشاهده پروفایل

استاد

University of California, Los AngelesUnited States

Tamir Gonen is a Professor of Biological Chemistry and Physiology at the David Geffen School of Medicine, University of California, Los Angeles (UCLA) , and an Investigator at the Howard Hughes Medical Institute (HHMI) . He is a pioneer in microcrystal electron diffraction (MicroED) , a transformative cryo-EM method for atomic-resolution structure determination. Education: Doctor of Science (DSc), University of Auckland (2025) PhD in Structural Biology, Harvard Medical School (2005) PhD in Biochemistry, University of Auckland (2002) BSc (Hons) in Inorganic Chemistry and Biochemistry, University of Auckland (1998) His research focuses on membrane protein structure and function , particularly those in the blood-brain barrier , using MicroED, X-ray crystallography, NMR, and molecular dynamics. He has determined structures of ion channels, transporters, and drug compounds at resolutions better than 1 Å, advancing drug discovery and understanding disease mechanisms. Recent work includes high-throughput MicroED for ion channel dynamics, energy filtering to enhance resolution, and polymorphic drug characterization . His lab also develops protocols for suspended drop crystallization and focused ion-beam milling of samples. Scientific Awards: Fellow, American Crystallographic Association (2025) Doctor of Science, University of Auckland (2025) Carl Branden Award, The Protein Society (2024) Investigator, HHMI (2017) Member, Royal Society of New Zealand (2017) American Diabetes Association Career Development Award (2009) He leads the Gonen Lab , which emphasizes multidisciplinary approaches and method development in structural biology. His trainees have become faculty at top global institutions, extending his impact on the field.

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Dobrev Dobromirمشاهده پروفایل

استاد

Graz University of TechnologyAustria

Dobrev Dobromir is a Full Professor and Director of the Institute of Pharmacology at the Faculty of Medicine, University Duisburg-Essen (Germany). He also holds adjunct professorships at Baylor College of Medicine (USA) and the Montreal Heart Institute (Canada). His research focuses on molecular mechanisms of atrial fibrillation, calcium handling, cardiac inflammation, and drug discovery for arrhythmias. He has authored over 400 peer-reviewed articles and serves as Editor-in-Chief of International Journal of Cardiology: Heart and Vasculature . Education and career highlights include roles as Chair of Experimental Cardiology at Heidelberg University (2010-2012), Postdoctoral Fellow at Dresden University of Technology (1994-1999), and leadership in the Transatlantic Networks of Excellence in Cardiovascular Research (2007-2013). He has received prestigious awards including an Honorary Doctorate from Carol Davila University (2022), Fellowships from the Heart Rhythm Society (FHRS, 2022), and multiple teaching awards (2021). His research bridges basic science and clinical applications, emphasizing inflammatory pathways in atrial remodeling and identifying novel therapeutic targets. He actively contributes to professional organizations including the European Society of Cardiology (ESC), serving as Chair-Elect of its Cardiovascular Pharmacotherapy Working Group. Dr. Dobrev’s work has been published in high-impact journals like Nature Reviews Cardiology , Circulation , and The Lancet , reflecting his global influence in cardiovascular research.

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Rachel C Mylesمشاهده پروفایل

استاد

University of GlasgowUnited Kingdom

Professor Rachel C Myles is the Chair of Cardiac Electrophysiology at the University of Glasgow’s School of Cardiovascular and Metabolic Health, and an Honorary Consultant Cardiologist in the West of Scotland Inherited Cardiac Conditions Service. She holds a first-class degree in Physiological Sciences from the University of Oxford and trained in medicine at Guy’s and St. Thomas’ before completing a PhD in experimental electrophysiology under Prof Godfrey Smith. Her research combines clinical expertise in inherited arrhythmias with experimental work investigating arrhythmia mechanisms in heart failure and cardiomyopathy. Key areas include ventricular arrhythmia initiation, calcium handling defects, and therapeutic target identification. She has held a Wellcome Trust Intermediate Fellowship to establish her independent lab and currently leads projects on cardiac tissue engineering, cardiotoxicity screening in cardio-oncology, and electrophysiological biomarkers for sudden death risk stratification. Education: MB ChB from Guy’s/King’s/St Thomas’ Medical School; DPhil in Cardiovascular Physiology from University of Glasgow. Research focuses on cellular mechanisms underlying ventricular arrhythmias, particularly the role of repolarization alternans and ryanodine receptor dysfunction. Her group uses optical mapping, stem cell-derived models, and computational approaches to bridge cellular findings with clinical arrhythmia outcomes. Notable contributions include defining adrenergic receptor subtype roles in arrhythmia promotion and developing methods to assess myocardial infarction models in small animals. Recent work highlights include engineering heart tissues for cardiac repair, identifying IL-6 as a prognostic marker in heart failure, and investigating hypothermia’s dual effects on arrhythmia risk. Over 35 peer-reviewed papers published in journals like Circulation Research and Cardiovascular Research, with grants from BHF, Wellcome Trust, and Academy of Medical Sciences. Supervised students Eleanor Dickson-Murray (palmitoylation studies) and Kyle Shead (cardio-oncology toxicity screening). Grants/Awards: Wellcome Trust Intermediate Fellowship (2015-2020), multiple BHF Project Grants (2010-2025), Academy of Medical Sciences Starter Grant (2013-2015).

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Toby Allenمشاهده پروفایل

استاد

RMIT UniversityAustralia

Professor Toby Allen is a computational biophysicist at RMIT University (School of Science, City Campus Australia). His work focuses on membrane transport phenomena, ion channel mechanisms, and computational modeling of biological systems. He holds an ORCID 0000-0002-3521-7950 and is open to supervising Masters/PhD students. PhD, Australian National University (1998) Revson Fellow & Keck Fellow, Cornell University (2001-2004) Assistant Professor, UC Davis (2004-2009) Vice Chancellor’s Senior Research Fellow, RMIT University (2011-present) Research spans Biophysics , Computational Modeling , and Membrane Protein Dynamics . Key areas include: Ion channel selectivity mechanisms Membrane transport of charged molecules Computational pharmacology of ion channels Structural dynamics of ATPases Role of membrane electrostatics in transport Scientific contributions recognized through: Revson Fellowship , Cornell University Keck Fellowship , Cornell University NSF Career Award , UC Davis Chancellor’s Fellow , UC Davis His group receives funding from the Australian Research Council , NHMRC , NIH , and supercomputing agencies. Teaching responsibilities include Statistical Physics and Electromagnetism courses.

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