جستجوی استاد راهنمای دانشگاهی

Dr. Keith Alexander Sharkey is a Professor in the Department of Physiology and Pharmacology at the Cumming School of Medicine, University of Calgary. He is also a Full Member of both the Hotchkiss Brain Institute and The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases. Dr. Sharkey has been at the University of Calgary since his appointment as Assistant Professor in 1990, dedicating his career to understanding the neural control of the gastrointestinal tract. From 2005-2021, he held the Crohn's and Colitis Canada Chair in Inflammatory Bowel Disease Research, demonstrating his longstanding commitment to advancing knowledge in gastrointestinal sciences. Dr. Sharkey's educational journey began with a BSc (Hons) in Nutrition from the University of London in 1981, followed by a PhD in Physiology from the University of Liverpool in 1985. After completing postdoctoral training in Hungary, the UK, and Canada, he joined the University of Calgary faculty in 1990, where he has remained throughout his distinguished academic career. Dr. Sharkey's research program centers on understanding the physiology and pathophysiology of the neural control of the gastrointestinal tract and brain-gut interactions in health and disease. His laboratory investigates two main areas: the role of the endocannabinoid system in regulating GI motility and intestinal barrier function, and the physiology of the enteric nervous system in controlling motility and barrier function. His work employs state-of-the-art approaches including live cell imaging and molecular genetics. Recent publications show his expanding interest in connections between gut function and neurodegenerative conditions like ALS, with multiple 2024-2025 papers examining sexual dimorphism in disease processes and gut-brain axis mechanisms. Fellow, Royal Society of Canada (2024) Cumming School of Medicine's van de Sande Distinguished Achievement Award for Mentorship (2021) Distinguished Research Award, American Physiological Society (2021) Finkelstein Award for Excellence, Crohn's and Colitis Canada (2016) Fellow, Canadian Academy of Health Sciences (2015) Fellow, Canadian Association of Gastroenterology (2015) Killam Annual Professor Award, University of Calgary (2013) Dr. Sharkey has mentored numerous students throughout his career, as evidenced by his 2021 Mentorship Award. His research is supported by significant funding, including a CIHR Foundation grant exploring how enteric nerves and glia maintain intestinal homeostasis. He has also participated in university strategic initiatives focused on Brain and Mental Health (2015-2021) and Infections, Inflammations and Chronic Diseases (2015-2021), demonstrating his interdisciplinary approach. The Sharkey Lab provides a safe, inclusive, and diverse research environment that encourages open scientific exchange from diverse viewpoints. His laboratory is actively engaged in multiple collaborative projects, including investigations with UBC Okanagan on diet and probiotics targeting the gut-brain metabolic interactome, and with University of Calgary colleagues studying gut microbiota's role in ALS. Dr. Sharkey continues to advance our understanding of neural mechanisms controlling gastrointestinal function with upcoming courses scheduled for Fall 2024 and Winter 2025.

• Enteric nervous system
• Gut-brain axis
• Endocannabinoid system
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Calliope Dendrou is an Associate Professor in Clinical Pathology and Inflammation at the Kennedy Institute of Rheumatology (KIR), University of Oxford, leading the Immune Disease Multiomics Laboratory. She previously held a Wellcome & Royal Society Sir Henry Dale Fellowship at the University of Oxford’s Centre for Human Genetics before joining KIR in 2023. Her research focuses on immune disease mechanisms using multiomics approaches, including genomic profiling to identify therapeutic targets across tissues and immune-mediated diseases. She co-leads large-scale projects like the Oxford-J&J Cartography Consortium and the Chan Zuckerberg Initiative’s LEGACY Network, and teaches on the MSc in Genomic Medicine program. Educational Background: BSc (Biology, Imperial College London, 2005; Forbes Memorial Medal Winner); PhD in Infection & Immunity (University of Cambridge, 2010). Postdoctoral training at the Weatherall Institute of Molecular Medicine under Prof. Lars Fugger. Research interests include immunogenetics, cytokine signaling pathways, drug repositioning, and cross-disease pathophysiology. Her work integrates single-cell and spatial transcriptomics to dissect immune-cell interactions in diseases like rheumatoid arthritis, inflammatory bowel disease, and celiac disease. Recent articles highlight her contributions to understanding vaccine adjuvant responses, Th17 cell roles in spondyloarthritis, and immune-epithelial networks in celiac disease. Collaborations emphasize multi-omic data analysis (e.g., Panpipes pipeline) and translational studies toward precision medicine. Awards: Forbes Memorial Medal (BSc), Wellcome & Royal Society Sir Henry Dale Fellowship. Leadership roles include Equality, Diversity, and Inclusion Champion and 'Single-Cell & Spatial Omics for Precision Medicine' Module Lead. Lab & Teams: Immune Disease Multiomics Lab at KIR. Active in collaborative initiatives such as the LEGACY Network, focusing on large-scale immune profiling in ancestrally diverse populations.

• Immunology
• Genomics
• Multiomics Analysis
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Manuel R. Amieva is a Professor at Stanford University School of Medicine , holding joint appointments in Pediatrics - Infectious Diseases and Microbiology & Immunology . He is also a member of the Maternal & Child Health Research Institute (MCHRI) . His clinical practice at Stanford Medicine Children's Health focuses on pediatric infectious diseases. Education: Medical Education: Stanford University School of Medicine (1997) Fellowship: Stanford University Pediatric Infectious Disease Fellowship (2004) Internship & Residency: Stanford Health Care at Lucile Packard Children's Hospital (1998-1999) Dr. Amieva's research investigates host-pathogen interactions at epithelial barriers, with specific expertise in Helicobacter pylori , Listeria monocytogenes , Salmonella enterica , and Staphylococcus aureus . His lab develops innovative organoid culture systems with controlled polarity to study microbial colonization and oncogenic mechanisms. Key discoveries include: H. pylori's manipulation of epithelial junctions via the CagA protein Listeria's exploitation of cell extrusion sites for invasion Staphylococcus toxin interactions with adherens junctions Gastric stem cell activation by pathogens Recent publication trends show continued leadership in infectious disease mechanisms (2020-2025), with a focus on: Pathogen-specific epithelial breach strategies Organoid modeling of viral/bacterial interactions Redox-dependent host factor regulation Single-cell spatial transcriptomic analyses Multi-institutional educational frameworks His scientific collaborations span disciplines including: Gastric cancer genomics initiatives COVID-19 lung infection models Stem cell-microbe interactions Medical education reform projects Dr. Amieva maintains active clinical research while mentoring students in both the Microbiology & Immunology and Pediatrics programs. His lab at Stanford employs advanced 3D confocal microscopy and organ-on-a-chip technologies to visualize epithelial colonization dynamics.

• Microbiology
• Infectious Diseases
• Cell Biology
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Dr. Michael Baym is an Associate Professor of Biomedical Informatics at Harvard Medical School with affiliate appointments in Microbiology and the Laboratory of Systems Pharmacology, and as an Associate Member of the Broad Institute. He leads the Baym Lab, which studies microbial evolutionary genomics and antibiotic resistance through a hybrid of experimental, computational, and theoretical approaches. His research focuses on: Antibiotic Resistance Evolution and practical interventions Mobile Genetic Elements (plasmids, phages, transposons) Computational Genomic Algorithms for big data analysis Synthetic Biology tools and technologies Key recent publications explore phage discovery systems , phylogenetic compression of microbial genomes, and RNA-guided gene drives in plasmids. His work is supported by multiple NIH/NIGMS and NSF grants including a MIRA award. Scientific honors include: Packard Fellowship (2018) Pew Biomedical Scholarship (2020) Sloan Research Fellowship (2020) A. Clifford Barger Excellence in Mentoring Award (2021) SSQBio Mentorship Award (2022) The lab actively trains PhD students and postdoctoral fellows with alumni occupying academic and industry positions globally. Current team members include researchers from interdisciplinary backgrounds working at the intersection of experiment, computation, and theory .

• Microbial Evolutionary Genomics
• Antibiotic Resistance
• Computational Biology
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Joseph P. Bressler is an Associate Professor at Johns Hopkins University, jointly affiliated with the Bloomberg School of Public Health and the Krieger School of Arts and Sciences. He is a member of the Department of Environmental Health and Engineering and conducts research at the Kennedy Krieger Institute in Baltimore, Maryland. His work bridges public health, neuroscience, and molecular toxicology, focusing on environmental impacts on brain development. Education: PhD, Rutgers University, 1978 Dr. Bressler’s research centers on neurotoxicology, particularly how environmental pollutants such as lead, cadmium, and aluminum disrupt metal transport systems and affect neurodevelopment. His laboratory investigates the role of iron and other metal transporters at the blood-brain barrier and in glial cells, revealing mechanisms of metal uptake and toxicity. His work has implications for understanding autism, fetal alcohol syndrome, and other neurodevelopmental disorders. His recent publications highlight ongoing research into metal homeostasis, cytotoxicity in cancer and neuronal cell lines, e-cigarette aerosol variability, and epigenetic changes in sex chromosome aneuploidies. The research spans molecular mechanisms, in vitro models, and human health outcomes, demonstrating a multidisciplinary approach to environmental health. Scientific Contributions: Elucidated how lead and cadmium hijack iron transporters to enter the brain Demonstrated aluminum activation of iron uptake pathways in glial cells Investigated flavoring agents like ethyl maltol in enhancing metal toxicity Explored epigenetic and behavioral impacts in rare genetic conditions Dr. Bressler has advised numerous researchers and collaborators across disciplines. His work has been supported by federal and institutional grants, though specific funding details are not provided in the source text. He actively publishes in high-impact toxicology and environmental health journals, with research cited in policy and public health discussions. He leads a research laboratory focused on cellular and molecular mechanisms of neurotoxicity, utilizing in vitro models of the blood-brain barrier, astrocytes, and neuronal cell lines. His team collaborates widely across neuroscience, public health, and environmental engineering domains.

• Neurotoxicology
• Environmental Health Sciences
• Metal Transporters
• +۱۲ مورد دیگر

Konstantinos Kalogeropoulos is an Assistant Professor at the Department of Biotechnology and Biomedicine, Technical University of Denmark (DTU), leading research at the Cell Diversity Lab. His work bridges proteomics, computational biology, and snake venom research. Current projects: "The Proteomic Landscape during Influenza Infection" (2022-2025) Supervisor for PhD projects on protease network rewiring in psoriasis and wound exudate degradomics Research interests include: Proteomic analysis of inflammatory diseases Snake venom toxin structure prediction Extracellular matrix biomechanics De novo peptide sequencing algorithms Computational modeling of protease networks Recent article trends demonstrate his work in • Database-free proteomics (InstaNovo/InstaNexus) • Snake venom pathophysiology (V-ToCs clustering) • Inflammatory disease biomarkers (psoriasis, impaired healing) • Extracellular matrix mechanics (fibronectin tension, gut inflammation) Advising: Supervises PhD students Polhaus, C. J. M. and Haack, A. M., focusing on protease networks and wound healing.

• Proteomics
• Snake Venom Research
• Protein Structure Prediction
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Thomas Winkler is an Associate Professor at the Division of Micro and Nanosystems, KTH Royal Institute of Technology, Sweden, and collaborates with TU Braunschweig, Germany. His research focuses on solving life science challenges using microsystems tools, particularly in neuropsychiatric disorders like schizophrenia. He develops organ-on-chip models, engineered microfluidic platforms, and biosensors for point-of-care diagnostics. Winkler leads an interdisciplinary ERC-funded team addressing metabolic coupling in neurovascular units and oxidative stress biomarkers. Key achievements include the ERC Starting Grant (2023) and work on electrochemical sensors for clozapine monitoring. He teaches courses such as Microsystem Technology (EK2350) and supervises PhD and postdoctoral researchers. Current projects include machine learning-guided robotic organoid maturation and electrochemical technology development for the CHIPzophrenia initiative. His lab actively seeks talent through open positions in Stockholm and Braunschweig. Scientific awards include the ERC Starting Grant and Marie Skłodowska-Curie Actions Fellowship. Research spans sensor development, microfabrication, and biomaterials, with a focus on translating lab technologies to clinical applications. Collaborations bridge engineering and life sciences, emphasizing personalized mental healthcare solutions.

• Microsystems Technology
• Organ-on-Chip
• Neuropsychiatric Disorders
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Elin Org is a Professor of Microbiomics at the University of Tartu's Institute of Genomics, where she also serves as Head of the Estonian Genome Centre and Vice Director of the Institute. Her academic career spans over two decades with significant contributions to microbiome and genomic research. Education: PhD in Genetics, University of Tartu (2006) Master's Degree in Molecular Biotechnology and Biomedicine, University of Tartu (2000) Bachelor's Degree, University of Tartu (1997) Classical Singing, Heino Eller Tartu Music School (1996) Professor Org's research primarily focuses on the intricate relationships between host and gut microbiota and their influence on metabolism and common complex diseases. Her work bridges microbiomics, genomics, and complex disease research, with particular emphasis on understanding how gut microbiome composition affects human health. She has pioneered research connecting long-term antibiotic usage with microbiota-dependent effects and has made significant contributions to understanding the role of gut microbiome in conditions such as gestational diabetes, endometriosis, and polycystic ovary syndrome. Her approach integrates advanced computational methods with comprehensive health data to uncover causal relationships in microbiome research. Her recent publications demonstrate a strong trend toward integrating microbiome data with extensive digital health metrics, using machine learning approaches to identify microbial predictors of health outcomes. This work is increasingly focused on translating microbiome research into clinical applications for disease prediction and personalized medicine approaches, particularly in the context of the Estonian Biobank initiative. Major Scientific Recognition: 2025 National Science Award in medical and health sciences 2023 and 2022: Recognized among the world's top 1% most cited researchers by Clarivate Analytics 2020: Member of AcademiaNet, a portal for top female researchers 2017: EMBO Installation grant 2013: Marie Curie International Outgoing Fellowship Professor Org has secured substantial research funding as principal investigator for multiple significant projects, including 'DISCERN - Discovering the causes of three poorly understood cancers in Europe' (€245,466, European Commission) and 'Improving colorectal cancer screening and prediction using microbiome-based biomarkers' (€760,450, Estonian Research Council). She has served as an opponent for numerous PhD theses across European institutions, contributing to the development of emerging researchers in her field. As Head of the Estonian Genome Centre, Professor Org leads a multidisciplinary research team that plays a crucial role in Estonia's transition from biobanking to personalized medicine applications. She is actively involved in international collaborations through COST networks including INFOGUT (focused on in vitro colon models) and ML4Microbiome (statistical and machine learning techniques in human microbiome studies), positioning her at the forefront of global microbiome research initiatives.

• Microbiomics
• Genomics
• Complex Diseases
• +۴ مورد دیگر

John F. Brooks II is an Assistant Professor in the Department of Molecular Biology at Princeton University, where he leads the Brooks Lab. His research focuses on the circadian regulation of host-microbe dynamics, particularly how the circadian clock interfaces with the immune system to maintain gut microbiome harmony. Education: Ph.D., Northwestern University Feinberg School of Medicine, Walter S. and Lucienne Driskill Graduate Training Program in Life Sciences B.S., University of Michigan, Microbiology Research Interests: Dr. Brooks investigates how the circadian clock controls the rhythmic secretion of antimicrobial proteins (AMPs) in the small intestine and how persistent infections override these rhythms to sustain AMP production. His work integrates cell and molecular immunology, mouse genetics, and genomics to uncover mechanisms of circadian-immune crosstalk. This research has broad implications for disorders linked to circadian disruption, including obesity, diabetes, and chronic gut inflammation. Recent Publication Trends: His recent publications emphasize the coordination between microbial signals and host circadian rhythms in regulating innate immunity. Key themes include diurnal patterns in immune function, microbiota-driven immune modulation, and the physiological consequences of circadian misalignment in infection and disease. Scientific Awards: Pew Scholar in the Biomedical Sciences (2024) Advising and Grants: Dr. Brooks mentors graduate students and postdoctoral researchers, including Talia Akoh-Arrey and Urbashi Basu. His lab has received significant funding, notably the Pew Biomedical Scholars Award, supporting innovative research at the intersection of immunology, microbiology, and chronobiology. Labs and Teams: The Brooks Lab at Princeton employs interdisciplinary approaches to study host-microbe interactions. The team collaborates with experts in immunology and circadian biology, including Lora Hooper and Joseph Takahashi, to advance understanding of temporal regulation in immunity.

• Circadian Biology
• Immunology
• Microbiome
• +۷ مورد دیگر

Dr. Rebecca Clark is an Associate Professor in the Department of Biosciences at Durham University. Her research focuses on understanding intestinal function in health and disease using the Drosophila model. She investigates how the intestinal epithelium balances barrier function, nutrient absorption, microbial symbiosis, and cell turnover, particularly during aging and disease states. Key research questions include mechanisms of intestinal barrier failure and the interplay between nutrition and intestinal homeostasis. Her work integrates genetic, microbiological, and physiological approaches to explore aging-related pathologies. Current projects aim to identify molecular pathways linking intestinal health to longevity. Supervised postgraduate students include Ale Acevedo Marcelin, Beñat Yanez, and Fanila Shahzad. Dr. Clark’s lab uses Drosophila as a model system due to its powerful genetic tools and evolutionary relevance. Research has implications for understanding human conditions such as inflammatory bowel disease and age-related metabolic disorders. Recent findings highlight microbiota-independent aging mechanisms and the role of tricellular junctions in stem cell regulation. No scientific awards are explicitly listed in the provided materials. Her research has been published in journals like Cell , Nature Cell Biology , and Proceedings of the National Academy of Sciences .

• Intestinal Homeostasis
• Aging Biology
• Microbial Ecology
• +۳ مورد دیگر

Manuel Kleiner is an Associate Professor in the Department of Plant and Microbial Biology at North Carolina State University. His research focuses on metabolic and physiological interactions in host-microbe systems, microbial ecology, and the application of metagenomics and high-resolution mass spectrometry to study complex microbiota-host relationships. Research Highlights: Development of metaproteomic techniques to quantify protein expression, analyze community structure via biomass contributions, and track isotope ratios to understand nutrient flow between hosts and microbiota. Creator of the "transductomics" approach to detect horizontal gene transfer via viral transduction in intestinal systems. Collaborates with researchers such as Theriot, Sartor, Sheikh, Ziegler, and Gonzalez. Recent Trends: His 2025 publications emphasize gut microbiome dynamics, maize root-microbe interactions, transplantation biology, and advancements in metaproteomic methodologies. Key themes include dietary impacts on microbiota, stable isotope probing, and synthetic microbial communities for plant and human health. Laboratory Tools: The Kleiner Lab utilizes quantitative metagenomics, high-resolution mass spectrometry, and computational modeling to dissect functional interactions in symbiotic systems across diverse environments, from marine organisms to agricultural crops.

• Host-Microbe Interactions
• Microbial Ecology
• Metaproteomics
• +۷ مورد دیگر

David Walker is a Professor and Vice Chair of Academic Personnel in the Department of Integrative Biology and Physiology at the University of California, Los Angeles. He leads a research lab focused on understanding the molecular and cellular basis of aging, utilizing Drosophila melanogaster to investigate mechanisms such as mitochondrial dysfunction, autophagy, and intestinal barrier integrity. His work aims to identify therapeutic targets for age-related diseases. Education: B.S., Genetics, Queen's University Belfast (1995) MRes, Molecular Biology, University of Manchester (1996) Ph.D., Genetics, University of Manchester (2000) Walker's research interests center on the biological processes driving aging, with emphasis on mitochondrial dynamics, neurodegeneration, and gut-microbiota interactions. His lab employs genetic, molecular, and physiological approaches in Drosophila to dissect how cellular deterioration impacts lifespan and healthspan, bridging insights to human aging pathologies. Key themes include the role of autophagy adaptors (e.g., p62/SQSTM1), mitochondrial fission, and intestinal homeostasis in longevity. His recent publications (2014–2024) reveal a consistent focus on brain aging, mitophagy, and gut-brain axis disruptions, with trends toward identifying midlife interventions for healthspan extension. Articles frequently integrate cellular stress responses, metabolic regulation, and neurodegeneration, highlighting Drosophila as a versatile model for translational aging research. No scientific awards, prizes, or fellowships are mentioned in the provided text. While specific grants or student advisees are not detailed, Walker's lab actively mentors researchers and contributes to collaborative projects on aging mechanisms. Future directions may involve exploring mitochondrial-immune interactions and novel longevity pathways. Walker directs a Drosophila-focused laboratory at UCLA, emphasizing genetic screens and mechanistic studies to uncover evolutionarily conserved aging pathways. The team investigates tissue-specific aging cascades, including neuronal and intestinal systems, to develop strategies for mitigating age-related decline.

• Aging
• Mitochondrial Biology
• Neurodegeneration
• +۳ مورد دیگر

Jashvant Unadkat, Ph.D. is a Professor of Pharmaceutics at the University of Washington School of Pharmacy. He holds appointments in the Department of Pharmaceutics and is actively involved with the UWPKDAP (Program on Pharmacokinetics of Drugs of Abuse during Pregnancy). His research spans drug transport, metabolism, and pharmacokinetics with special emphasis on pregnancy and fetal pharmacology. Dr. Unadkat received his B.Pharm. from the University of London (1977), his Ph.D. from the University of Manchester (1982), and completed postdoctoral training at the University of California at San Francisco (1982-85). His educational background laid the foundation for his extensive career in pharmaceutical sciences. His research interests focus on mechanisms of drug transport and metabolism, particularly during pregnancy. Dr. Unadkat has made significant contributions to understanding placental drug transporters, blood-brain barrier function, and quantitative approaches to pharmacokinetics-pharmacodynamics. His work bridges computational modeling with experimental approaches to address complex questions in drug disposition. Analysis of his recent publications reveals a strong trend toward understanding drug interactions during pregnancy, cannabinoid pharmacology, and the application of physiologically based pharmacokinetic (PBPK) modeling to predict drug behavior in special populations. His research spans pharmacology, computational biology, obstetrics, and toxicology with particular emphasis on drug transporters and their regulation. Fellow of AAAS Fellow of AAPS Fellow of JSSX AAPS Research Achievement Award (2012) ISSX Research Achievement Award (2023) Founding co-chair (1999-2001) of AAPS focus group on Drug Transport and Uptake Dr. Unadkat has led significant research initiatives including the UW Research Affiliates Program on Transporters (UWRAPT) for 10 years, the NIDA-funded UWPKDAP program on drug disposition during pregnancy, and co-leads the NICHD-funded UW Transporter Elucidation Center. His work has generated over 250 peer-reviewed publications and has significantly influenced regulatory science and drug development practices. He is actively involved in research teams focusing on placental transport, hepatic drug metabolism, and quantitative pharmacology. His current work with the UW Transporter Elucidation Center aims to identify and characterize novel transporters in the placenta and developing intestine, with implications for drug safety during pregnancy and pediatric pharmacotherapy.

• Pharmacokinetics
• Pharmacodynamics
• Drug Transporters
• +۷ مورد دیگر

Felix Schweizer is Professor of Neurobiology at the David Geffen School of Medicine, University of California, Los Angeles, and concurrently serves as Interim Director of the Brain Research Institute and Chair of the Graduate Interdepartmental Program for Neuroscience, reflecting his leadership in both research and graduate training. Education Ph.D. in Biochemistry (summa cum laude), University of Basel, 1989 Research Interests Schweizer’s laboratory focuses on the molecular mechanisms of synaptic transmission and neuronal communication. Using electrophysiology, optical imaging, and quantitative proteomics, his group investigates how protein ubiquitination dynamically regulates neurotransmitter release and neuronal excitability. Recent projects explore microbial metabolite sensing by vagal afferents, the synaptic impact of environmental toxicants linked to Parkinson’s disease, and how gravitational load alters vestibular synaptic architecture. Collaborations with Drs. James Wohlschlegel (multiplexed SILAC proteomics), David Krantz (pesticide neurotoxicology), and Larry Hoffman (vestibular biology in altered gravity) extend the lab’s reach from molecular mechanisms to systems-level neuroscience. Scientific Awards No specific awards are listed in the provided text. Advising & Grants As Chair of the Graduate Interdepartmental Program for Neuroscience, Schweizer oversees interdisciplinary Ph.D. training across UCLA. The laboratory continuously hosts post-doctoral fellows and graduate students, and recent funding supports work on ubiquitin-mediated synaptic modulation, pesticide-induced neurodegeneration, and spaceflight-induced synaptic plasticity in the vestibular system. Labs & Teams The Schweizer laboratory, located in the Center for Health Sciences at UCLA, integrates electrophysiology, advanced imaging (serial EM and EM tomography), and biochemical approaches to dissect synaptic function across rodent, Drosophila, and human tissue models.

• Neurobiology
• Synaptic transmission
• Neurotransmitter release
• +۵ مورد دیگر

Toni M. Antalis, PhD, is a Professor in the Department of Pharmacology & Physiology at the University of Maryland School of Medicine. She serves as Associate Director of Training and Education for the Marlene and Stewart Greenebaum Comprehensive Cancer Center and Director of the Program in Molecular Medicine. Her research bridges vascular biology and cancer, focusing on membrane-anchored serine proteases and their role in tumor metastasis, inflammation, and coagulation. Doctorate in Biochemistry from Rice University Postdoctoral training in Cell Biology at Baylor College of Medicine Her laboratory investigates how protease-activated receptors (PARs) and the plasminogen activation system influence vascular disease and ovarian cancer progression. Current projects include studying fibrinolysis in thrombus resolution and developing protease-targeted therapies for metastatic ovarian cancer. Recent publications highlight roles of matriptase, testisin, and PAI-2 in tumor dissemination and vascular permeability. Dr. Antalis' research is funded by the National Institutes of Health (NIH), the Department of Defense, and a VA Merit Award. She has previously received support from the Lance Armstrong Foundation and Rivkin Center. She co-directs NIH-funded T32 and PREP programs for cancer training. Mentored numerous PhD students and postdoctoral fellows Developed engineered anthrax toxin prodrugs for ovarian cancer therapy (patents 10,568,929 and 11,013,784)

• Vascular Biology
• Ovarian Cancer
• Inflammation
• +۶ مورد دیگر